Professor Pimentel emphasizes the importance of reaction rate in determining the utility of chemical reactions. The reaction H2 + I2 -> 2HI is discussed in terms of activation energy and collision geometry. The reaction 4HBr + 02 2H20 + 2Br2 is shown to proceed by a series of two- particle collisions. The reaction 21 —» I2 is used as an example of a reaction in which a third particle must be involved in the collision to carry off the energy, or an alternate reaction path must be provided. The role of I2 in catalyzing this reaction is explained.