PROBLEMS OF HEREDITY 155 through undifferentiating cell-divisions with the original germ-cell from which the parental body developed. Even in ancient times men pondered over the re- semblances and differences between children and their parents—for like only tends to beget like — and wondered as to the nature of the bond which links generation to generation. But although the problems are old, the precise study of them is altogether modern. The first great step towards clearness was the formulation of the cell-theory by Schwann and Schleiden (1838-9), by Goodsir and Virchow, which made it clear that all but the simplest organisms are built up of cells or modifications of cells, and that the individual life usually begins as a fertilised egg-cell which proceeds by division and re-division, by differ- entiation and integration, to develop a more or less complex " body." It has become gradually clear that while the fertilised egg-cell gives rise to body-cells which become specialised, it also gives rise to un- specialised descendant-cells, which take no share in body-making, but become the germ-cells—the potential starting-points of another generation. A second great step was the accumulation of facts of inheritance showing that all sorts of qualities innate or inborn in the parents, essential and trivial, normal and abnormal, bodily and mental, may be transmitted to the offspring as part of the organic heritage. A third great step was implied in the acceptance which Darwin in par- ticular won for the general idea of descent, for it is hardly too much to say that the scientific study of the problems of heredity began when it was recognised that heredity is a fundamental condition of evolution* scientific and trans- s intrinsic incoherence; worthless as