PATHOGENIC BACTERIA. PART I. GENERAL CONSIDERATIONS. INTRODUCTION. IT is incorrect to begin the consideration of bacteriol- ogy, as is so often done, with the probable discoverer of bacteria, Leeuwenhoek, or with the so-called u Father of bacteriology," Henle. The controversies and ideas which stimulated the investigations and researches which have brought us to our present state of knowledge were begun hundreds of years before the beginning of the Christian era. Excepting such as taught and believed that u in six days the Lord made heaven and earth, the sea and all that in them is,1' or a kindred theory of the origin of things, the thinkers of antiquity never seem to have doubted that under favorable conditions life, both animal and vegetable, might arise spontaneously. Among the early Greeks we find that Anaximander (43d Olympiad, 610 B. c.) of Miletus held the theory that animals were formed from moisture. Empedocles of Agrigentum (450 B. c.) attributed to spontaneous genera- tion all the living beings which he found peopling the earth. Aristotle (B. c. 384) is not so general in his view of the subject, but asserts that ^sometimes animals are formed in putrefying soil, sometimes in plants, and some- times in the fluids of other animals".5' He also formulated a principle that u every dry substance which becomes moist, and every moist body which becomes dried, pro- duces living creatures, provided it is fit to nourish them.'* 2 17