i88 PA THOGENIC BACTERIA. of color-production, so that the centre of the growth is distinctly golden ; the edges may be white. Upon potato the growth is luxuriant, producing an orange-yellow coating over a large part of the surface. The potato-cultures give off a sour odor. When grown in bouillon the organism causes a diffuse cloudiness. In milk coagulation takes place, and is followed by gradual digestion of the casein. The Staphylococcus albus is exactly the same as the aureus, with the exception that in all media it is con- stantly colorless. Experiments have shown that the Staphylococcus aureus, like its congener, the albus, exists in an atten- uated form, and there is every reason to believe that in the majority of instances it inhabits the surface of the body in that condition. When virulent the golden Staphylococcus is a danger- ous and often deadly organism. Its pathogeny among animals is decided. When introduced subcutaneously, abscesses almost invariably follow, except in a certain few comparatively immune species, and not infrequently lead to a fatal termination. In such cases the organisms may be cultivated from the blood of the large vessels, though by far the greater number collect in, and fre- quently obstruct, the capillaries. In the lungs and spleen, and still more frequently in the kidneys, infarcts are formed by the bacterial emboli. The Malpighian tufts of the kidneys sometimes are full of cocci, and become the centres of small abscesses. The coccus is almost equally pathogenic for man, though the fatal outcome is much more rare. It enters the system through scratches, punctures, or abrasions, and when virulent generally causes an abscess, as various experimenters who inoculated themselves have discov- ered to their cost. Garre applied the organism in pure culture to the uninjured skin of his arm, and in four days developed a large carbuncle with a surrounding