SPIRILLA RESEMBLING CHOLERA. 341 In alkaline peptone solution a slow but luxuriant growth takes place. Spirillum Milleri.—This spirillum (Fig. 96) was found in the mouth by Miller in 1885. It: resembles the cholera ^. f, ^~ ; , FIG. 96.—Spirillum Milleri, from an agar-agar culture; x 1000 (Itzerott and Niemann). spirillum somewhat, but is much more like the spirillum of Pinkler and Prior, with which many bacteriologists think it identical. Upon gelatin the colonies are small, finely granular, have a narrow border-zone and a pale-brown color. The gelatin is rapidly liquefied. Upon agar-agar a thick yellowish layer is produced. The organism seems not to be pathogenic. Spirillum Aquatilis.—Giinther in 1892 found this or- ganism (Fig. 97) in the water of the river Spree. It is similar to the cholera spirillum in shape, has a long terminal flagellum, and is motile. The colonies which form upon gelatin are circular, have smooth borders, and look very much as if bored out with a tool. They have a brown color and are finely granular. In gelatin puncture-cultures the growth occurs almost exclusively at the surface. The agar-agar cultures are similar to those of cholera. Scarcely any development occurs in bouillon. By the