jes ies CLES Yi ‘ eae fs : ¢ - < : oe A * - P . ‘ 3 . ot < 2 ’ ae & : ¢ P Spee RA rapaesnenresr ee rrp meets: hires nad ss crn ent oe MEET a a al eee POLONIA DIE RINE PALLETS MOEA EPL SPLATT OO AINE IRIS OO ITF SO LEILA DIT, PPR IL DL OE PITRE III i is ee pe Ey rae aie Glass_¢> /~F¢, Rook eRe g ) Te Copyright N° COPYRIGHT DEPOSIT: ~ 4 Pu =¥ VETERINARY MEDICINE SERIES No. 5 Edited by D. M. CAMPBELL, D. V. S. CANINE MEDICINE AND SURGERY BY CHAS. G. SAUNDERS, V.S., B. V. Se. SENIOR PROFESSOR ONTARIO VETERINARY COLLEGE, PROFESSOR CANINE AND FELINE MEDICINE ONTARIO VETERINARY COLLEGE, EDITOR CANINE DEPARTMENT AMER- ICAN JOURNAL OF VETERINARY MEDI- CINE, O. C. No. 2 SEcT. CANADIAN ARMY VETERINARY Corps, Etc. Chicago AMERICAN JOURNAL OF VETERINARY MEDICINE 1915 a te ; | ? a CopyricHt, 1915, bs D. M. CAMPBELL PREFACE i: offering this little work to the profession the author wishes to point out that it is published mainly for the use of senior students and practi- tioners. It presumes a knowledge of pathology, histology and anatomy, and aims to deal only with the clinical aspect of the various diseases. It does not presume to be an encyclopedia, but deals merely with the conditions commonly found in everyday practice. If it succeeds in arousing more interest in and deeper study of canine practice, the author feels that his labor will not have been in vain. Toronto, Ont. Ce Ges. SENATOR VEST’S EULOGY ON THE DOG The best friend a man has in this world may turn against him and become his enemy. His son and daughter that he has reared with loving care may become ungrateful. Those who are nearest and dearest to us, those whom we trust with our happiness and our good name, may become traitors to their faith. The money that a man has he may lose. It flies away from him when he may need it most. Man's reputation may be sacrificed in a moment of ill-considered action. The people who are prone to fall on their knees and do us honor when success is with us may be the first to throw the stone of malice when failure settles its cloud upon our heads. The one absolutely unselfish friend a man may have in this selfish world, the one that never deserts him, the one that never proves ungrateful or treacherous, is the dog. A man’s dog stands by him in prosperity and poverty, in health and in sickness. He will sleep on the cold ground, when the winiry winds blow and the snow drives fiercely, if only he may be near his master’s side. He will kiss the hand that has no food to offer, he will lick the wounds and sores that come in encounter with the roughness of the world. He guards the sleep of his pauper master as if he were a prince. When all other friends desert, he remains. When riches take wings and reputation falls to pieces he is as constant in his love as the sun in its journey through the heavens. If fortune drives the master forth an outcast into the world, friendless and homeless, the faithful dog asks no higher privilege than that of accompanying him, to guard him against danger, to fight against his enemies, and when the last scene of all comes and death takes his master in its embrace and his body is laid away in the cold ground, no matter if all other friends pursue their way, there by his graveside will the noble dog be found, his head between his paws and his eyes sad, but open in alert watchfulness, faithful and true even to death. CONTENTS PACE | SECTION I. CUA TOTES CURIS WTO cg SIG ee aa ik ee Ra SECTION II. DISEASES OF THE UPPER RESPIRATORY PASSAGES............ Simple Nasal Catarrh— Rhinitis — Coryza — Epis- _taxis—Laryngitis—Chronic Laryngitis. SECTION III. DISEASES OF THE BRONCHI AND LUNGS... <¢ ..c/c csi see cee's Bronchitis—Acute Bronchitis—Chronie Bronchitis —Pneumonia—Lobar (Croupous) Pneumonia—Lobu- lar (Catarrhal) Pneumonia. SECTION IV. RSMAS MOR UTETH ETM UR.) wie «ote ars SpIritus; SUETIS: MILTOSI. Ji... wis 's/exs-oy s 0.0.808'e Min; xxx LTHEUSTOMS DILCEUNT wcaleNs)e esyeidnr boaters, enaratesaleyns es drs. iv M. Give four drams without water twice daily. The cough may be regulated by one-fourth-grain doses of codein sulphate every hour. In the second stage an expectorant cough mixture should be given, and stimulants as needed, of which there is none better than 1-200 to 1-60 grain of strychnin. Either of the following prescriptions may be used with good results: Pa ELeroin My OrOCHlOLIGI. isn oste et s\erbibis eo ee ess Spot Syr. tolutani, SCN FSC W IE CAE: Th SR BA VR Cee a, ni Ae Et IE drs. vi PAU HUE OM LOMOLO GINS: s2\) 554 Ses ielal ade Wiel b teeta Sretecs ozs. Vi M. Give two to four drams in water three times daily. vam V ahh: TNCCACUAMMGO:) cies s cin c auc ew weet ae min. xii Liquor ammonii acetatis, SMC OMCs it vista tclara eiavelersiapece. eral erate eaten dr. ss SA GSLCHUIE SRE RR sae RN eee eee min. xv PAM Re ter Geert e Peatetd te atom ye vids, sola eeuescvere,». ia drs. iv M. Give four drams three times daily. Should the bronchial tubes become loaded with mucus of which they are not able to rid themselves, and the animal’s breathing becomes greatly dis- tressed because of its interference with the passage of air, an emetic, of which the most effective is one thirtieth to one-tenth of a grain of apomorphin hydrochlorid, will give great relief, often averting suffocation. The after-treatment consists of a liberal diet and 20 CANINE MEDICINE AND SURGERY tonics, such as Blaud’s pills, one pill three times a day, or a granule composed of Be 4Stryehmim -arseniales nace soc 5 eee gr. 1-128 Iron arsenate, Quininarsenate;, advan seek cee noe gr. 1-64 Nucléin’ solugion J c5..2cdtere ate eee ence min. iv M. Give one half to three, three times daily, or give ferri et quinine arsenas, two to ten grains, three times daily. Chronic Bronchitis This is a sequel to cases of acute bronchitis which, owing to neglect or other reasons, merge into the chronic. It runs a varied course of from a few weeks to several months. Symptoms.—Continual coughing and _ expectora- _ tion is a symptom of chronic bronchitis. The cough is easily started by exertion or excitement, and the expectorated matter is tenacious and often of an offensive odor. The pulse and temperature as a rule are disturbed but little, although in some cases the latter may be slightly elevated. The animal’s appetite is variable, and it generally loses flesh and becomes more or less emaciated. Treatment.—The treatment consists in controlling the cough and the exhibition of expectorants, steam- ing with stimulating medicated inhalations, and the administration of tonics. In this condition “Guaialyptol,” a combination of guaiacol, eucalyptus, camphor, and phenic acid in _ oil has a markedly beneficial effect upon the mu- cous membrane and disinfects the entire respiratory tract. Cod-liver oil is also a most valuable re- constructive and should be given a trial. A liberal diet must be prescribed, and, as in all diseases of the organs of respiration, the importance of proper hygienic conditions must not be overlooked. PNEUMONIA 21 Pneumonia Like bronchitis, inflammation of the substance of the lungs is due to infection (pneumoccoccus, or Diplococcus pneumonie, and various Streptococci and Micrococci). ‘It may also be caused by the spread of inflammation from other parts, as from the bronchial tubes in bronchitis or from the pleura in pleurisy. Again, it may be developed by the direct action of mechanical or other irritation, such as the inhalation of irritant gases or dust, or by vomition; or it may spring from the presence of emboli in the branches of the pulmonary artery or oi: tubercles or clots in the lung tissue; it may also occur as a complication of heart disease, kid- ney disease, rheumatism, debilitating diseases, dis- temper, tuberculosis, or echinococcosis. “Cold and wet, unhealthful surroundings, and a lowered vitality are undoubtedly — predisposing causes. Clinically, in the dog we have to deal with two forms of pneumonia, namely, lobar pneumonia, which is of rare occurrence, and lobular pneumonia, which is common. The words “diffuse” and “cir- cumscribed,” however, might be used to better ad- vantage, the type of the former variety being fur- nished by the idiopathic affection; that of the latter by the condition which is secondary to diseases of the air passages. The two varieties, however, merge into one another. Lobar (Croupous) Pneumonia This type begins with hyperemia of the small vessels which are distributed in the walls of the air cells and bronchial passages, a swelling and tend- ency to proliferation of the epithelial cells of these parts, and an exudation of serum and cellular ele- ments of the blood. The air vesicles and passages 22 CANINE MEDICINE AND SURGERY communicating with them gradually become filled and finally distended with this exudate, the air in them is expelled or absorbed by degrees, and the affected lung tissue becomes solid and heavy. If the parts be now examined microscopically, the dilated blood vessels will be found crowded with their corpuscular contents, and the alveoli full of cells, all blended together into a common mass either by an amorphous, glutinous cement, or by a delicate, fibrillated network. With the progress of the disease the contents of the air vesicles liquefy and acquire a purulent character. This liquefied exudate is removed partly by expectora- tion and partly by gradual absorption. Occasion- ally, however, this breaking up of the exudate is followed by a breaking down of the lung substance, abscess formation, and gangrene. The progress of a case of pneumonia through its various phases is quite gradual, but there are at least three stages that are more or less well marked. The first of these is the stage of en- gorgement (congestion, hyperemia), the second that of red hepatization, the third that of gray hepatiza- tion. In the first stage the lung still contains air, though in diminished quantity; it 1s deeply con- gested, exudes more moisture than is natural, is increased in weight, and is more friable than nor- mal lung tissue. This condition of the lung tissue is difficult to distinguish from hypostatic conges- tion, for which it must not be mistaken if found on autopsy. In the second Stage the lung is con- solidated; the cells have lost their air and the cavities are filled with adherent masses of cells; it is distended to its full size, and its constituent lobules are distinctly mapped out upon the sur- face. In this stage the lung will sink in water PNEUMONIA 23 and when sectioned it appears fairly dry and slightly granular, presenting a marbled aspect which is due to the intermixture of nearly colorless inflammiatory extfdate and areas of congestion. The third” stage differs from the second mainly in the assumption by the affected lung tissue of a fairly uniform, opaque, grayish, yellowish, or greenish tinge, in its largely increased friability, and in the ready exudation from the cut surface of a thick, turbid, purulent fluid; in some cases this exudate is comparatively scanty; in others it is so abund- ant that the lung is like a sponge saturated with pus. Since pneumonia tends to spread, it naturally follows that different portions of the affected lung often present well-marked differences of condition, and that we occasionally find all the recognized stages of pneumonia present at the same time in the, same case. Inflammation may involve the lung to a varied extent; thus it may be limited to a section no larger than a walnut or it may include the whole lobe or even a whole lung; and further, it may affect both lungs. The right lung is affected more frequently than the left, and the lower lobe more often than the upper. Symptoms.—Although of somewhat rare occur- rence, the symptoms of lobar pneumonia should be known by the veterinarian. The disease is ushered in with a day or two of lassitude and dullness, anorexia, and restlessness. The invasion of the dis- ease is generally marked by a rigor or a succession of rigors, and the temperature rises to 104 or 106 degrees Fahrenheit; the respirations are increased, in some cases up to sixty a minute. The breath- ing is shallow and labored and accompanied by more or less dyspnea; the cheeks are puffed out 24 CANINE MEDICINE AND SURGERY at each expiration. -There is a short, dry, painful cough. The pulse is full and bounding, running at the rate of 150 to 190 a minute- during the hyperemic stage, but becoming softer and weaker but still fast in the second and third stages. In cases approaching a favorable termination the pulse gradually regains its normal tone and rate, but in those cases that do not recover the pulse becomes weaker and weaker, until it is barely perceptible. While pneumonia is in progress the systemic veins are apt to become overloaded and the mucous membranes may assume a cyanotic tint, although usually they are congested and of a reddish color. Thirst is always increased, but loss of appetite is invariable. The condition of the bowels varies, and though the patient is usually constipated, some- times there is more or less diarrhea. The urine is scanty and dark colored. In the first stage of lobar or croupous pneumonia the most observable auscultatory phenomenon is minute crepitation, which may be audible during the whole of inspiration, sometimes during expira- tion as well, and not: infrequently at the end of a deep inspiration, such as that which precedes a cough. In association with this there may be no change or percussion or there may be high-pitched resonance. The second stage is marked by the supervention over the consolidated portion of the lung of cessation of the fine crepitation and the development in its place of well-marked tubular breathing; when, however, the bronchial tubes lead- ing to these consolidated areas are completely ob- structed there is total absence of respiratory sounds. When pleurisy is coexistent with pneumonia, as is often the case, the friction sound indicative of PNEUMONIA 25 that condition will also be heard. At a later stage, when the lung tissue is breaking down or resolu- tion is taking place, tubular breathing gives way to a sort of coarse crepitation to which the name crepitatio redux has been given. This gradually passes into the ordinary bronchitic rales. The sputum expectorated is of little diagnostic value in the dog, as it is almost invariably swal- lowed immediately it is coughed up. It is, however, at first transparent, very viscid, and tinged with blood, later it loses its sanguineous tint and_be- comes opaque and greenish, acquiring, in fact, a mucopurulent character, and then gradually dimin- ishes in quantity. In some cases, instead of undergoing these changes, which may be regarded as the normal changes, the sputum acquires a deep purplish or reddish-brown tint, and at the same time a more watery consistency. This form of sputum has been likened to prune juice and is gen- erally the sign not only of increased congestion and escape of blood but of the onset of the third stage. If attended by a disgusting fetor, it~ indi- cates the onset of pulmonary gangrene. In either case, it cannot but be regarded as an unfavorable symptom. Lobular (Catarrhal) Pneumonia This is the commonest pneumonia of the dog. In typical cases the lung is studded with pneu- monic patches varying in size from that of a pea to that of a walnut, each involving one or more pulmonary lobules, circumscribed by the interlobu- lar connective tissue and. separated from one an- other by a network of still crepitant, and, it may be, of perfectly healthy lung tissue. The pneumonic patches may be in the hyperemic condition only, in which case they may not be recognized or may 26 CANINE MEDICINE AND SURGERY present the features of ordinary red or gray hepa- tization. Further, by an extension of “the ‘disease; ime neighboring diseased areas may coalesce and thus extensive tracts of lung tissue become involved. Full lobular pneumonia is always secondary to the blocking up of ‘air passages, and especially those of capillary size; it may be excited either by the gradual extension of the inflammatory process from the tubes to the air vesicles, or by the entrance into the vesicles during inspiration of the inflamma- tory products of the tubes, which then act as irri- tants and carriers of infection. Closely related to lobular pneumonia is the dis- seminated pneumonia due to obstruction of small branches of the pulmonary artery, either by em- bolism or thrombosis, or in the course of pyemia. In these cases, as in the other, the affected areas are of small size and limited by the margin of the lobules. But there is a greater variety of result, especially in pyemia; in which, while the affected areas sometimes present simple hyperemia, or red or gray hepatization, they not infrequently are the seat of hemorrhage, or undergo rapid suppuration or gangrene. In all forms of pneumonia, even in such as are not of bronchitic origin, there is a tendency to the development sooner or later of bronchitis. But apart from this there is a marked disposition early in the course of pneumonia to the effusion into the tubes from the inflamed air cells of a transparent, very viscid fluid, uniformly stained with blood and containing cells; and in some rare cases this fluid, like that in the air cells whence it is derived, under- goes coagulation in the bronchial tubes, which thus PNEUMONIA 27 become filled to a greater or less extent with casts consisting of coagulated fibrin and cells. Fortunately, abscess formation is the exception rather than the rule in lobular pneunionia, the dis- ease seldom going beyond the third stage. Gangrene seldom occurs in idiopathic pneumonia, it being met with chiefly in those cases in which the pneumonia is secondary to or complicated with some other affection. It is characterized by the breaking down of the lung tissue into a fetid, dirty, greenish-yellow pulp, and by more or less greenish discoloration of the surrounding consoli- dated tissue. The gangrenous condition may involve either an extensive tract of lung tissue of several scattered areas or even a single small patch. The complications of pneumonia are pleurisy, bronchitis, icterus, and intestinal congestion. It is common to find on autopsy the right side of the heart filled with a fibrinous coagulum which is prolonged into the pulmonary artery (antemortem clot), while the left side is contracted and almost empty. Symptoms.—The lobular type, the common pneu- monia of the dog, attacks its victims insidiously during the progress of some. other disease, such as distemper or bronchitis. Its onset is not usually marked by rigors or the violent circulatory dis- turbances noted in the lobar form. In _ patients suffering from bronchitis or distemper the super- vention of this form of pneumonia may be sus- pected by an aggravation of the respiratory dis- turbance. The temperature mounts higher, the respirations are more labored, and the puffing out of the cheeks at each expiration more marked. Auscultatory and percussive phenomena are not so distinctive as in the idiopathic form, but apart from its insidious approach, longer course, and greater 28 CANINE MEDICINE AND SURGERY mortality, lobular pneumonia, with the exception noted, presents the same clinical symptoms as the idiopathic variety. Treatment.—The treatment of pneumonia of either the lobar or lobular, type, resolves itself into the treatment of conditions found, and the upkeep of the vital forces of the patient until the disease runs its course. The most modern method of treating pneumonia is by the pneumobacterin and antipneumococcic serum. The former combats the disease by raising the opsonic index of the patient, thus enabling the leukocytes to more effectually cope with the in- vading organisms (active immunity), and should be employed as soon as the diagnosis of pneumonia is positive. It may be used in doses corresponding to those used in human practice, namely twenty- five to fifty million dead bacteria injected hypoder- mically. It is not necessary to obtain the opsonic index, as variations in the temperature constitute a sufficient clinical guide. In cases responding to bacterin treatment the temperature will fall after the injection and then gradually rise again, when another injection should be given. The antiserum is used to neutralize the toxins already liberated by the organism and often produces great ameliora- tion of the symptoms (passive immunity). One of the most important factors in treating this, or for that matter, any other infectious dis- ease, is to secure free elimination for both the toxins produced by the infecting agents, and also for those manufactured in the animal’s own ali- mentary canal. In health these toxins are elimi- nated or neutralized, and their producers kept under control by the excretory organs and _ digestive juices. In disease, on the other hand, the functions PNEUMONIA 29 of the excretory organs and, in fact, the whole mechanism of the body, is more or less interfered with and thrown out of its normal equilibrium. In other words, we have to deal not only with toxins’ produced by the invading organisms, but with toxins produced by the animal itself, that is, with an autointoxication. Thus free elimination, both by the intestinal tract and the kidneys, must be maintained as the most essential part of the treatment. This may be accomplished by small doses of calomel, one- fourth grain every two hours to effect, or until one to two grains have been taken, and by the diuretic mixture given for the treatment of bronchitis. Constipation must never be allowed to persist. In sthenic cases, with a full, bounding pulse, the circulation must be equalized either by bleeding or, better still, by small, repeated doses of 1-1600 to 1-800 grain of aconitin every thirty minutes to effect, and then at intervals sufficient to keep the pulse within bounds. The same application to the chest wall as given under bronchitis should be applied, or equal parts of guaiacol and camphorated oil rubbed in and the thorax covered with a padded jacket. Abundance of fresh air should be allowed. The cough may be controlled by the administration of codein, one- fourth grain as required, and expectoration facili- tated by. inhalations and expectorant mixtures. Guaiacol is an extremely useful drug in this con- dition, being an antipyretic, stimulant, and respira- tory disinfectant. In the second and third stages an ever-watchful eye must be kept on the heart, and stimulants given as conditions indicate. Strychnin, 1-200 to 1-60 grain, is the drug most useful here, and it may be advantageously combined with 1-50 grain of digi- 30 CANINE MEDICINE AND SURGERY talin. Throughout the illness the diet must be light, nourishing, and easily digested. Milk, beef tea, and small quantities of finely chopped raw beef are appropriate articles of diet. In cases where the animal refuses to eat at all, extract of meat, made into pills, may be administered, or a teaspoonful each of brandy and beef tea may be given every two hours. The after-treatment of pneumonia consists of liberal diet, moderate exercise, and a good, iron tonic. In cases of pneumonia that take on a septic char- acter due to secondary infection (pyogenic bac- teria), all the usual symptoms are accentuated, there is the addition of great prostration, and the case only too often ends fatally. However, antt- streptococcic serum in full and repeated doses has in many cases saved life, and should be resorted to as soon as the secondary infection is diagnosed. Subcutaneous injections of camphor are particu- larly useful in these cases and should be repeated’ as required. Thirty to sixty minims of spirit of camphor may be given, or it may be given as fol- lows: Camphone. 22: S604 Sevens ot dae cog ean grs. Xv EXtheris sulphunicit sn ceincwase oes dr. ss Ole VOW Vee 5 xcs. s ho eon oe et COn he eee drs. ii M. Inject fifteen to thirty minims, according to the cir- cumstances. Gangrene of the lung is often the sequel of the secondary invasion in pneumonia and 1s_ nearly always fatal, but the above treatment should be persisted in, in the hope of inducing a favorable termination, See PONS bv DISEASES OF THE PLEURZ Pleurisy (Inflammation of the Pleura; Pleuritis) The disease is found in two forms, primary and secondary pleuritis. The primary form is usually , caused by exposure to cold, especially when the coat is wet, as in sporting dogs after swimming, or running through wet underbrush. Secondary pleurisy appears as a complication of other dis- eases, such as pneumonia, pericarditis, peritonitis (extending from the abdominal cavity through the diaphragm), fractured ribs, punctured wounds of the thorax, perforation of the esophagus by for- eign bodies, tuberculosis, or pyemia. Morbid Anatomy.—The pleura is dull and tume- fied and very hyperemic. Its surface is roughened by accumulations of fibrin and in appearance may be likened to the surfaces of two pieces of bread and butter that have been placed together and then separated. When there is no accumulation of fluid it is termed dry pleurisy, or pleuritis fibrinosa. Usually, however, exudation takes place and an accumulation of a serous fluid in which fibrinous coagula float, is found between the pleural folds. This pleuritic fluid, closely resembling blood serum, contains cells, and, according to the number of red blood corpuscles it contains, is of a straw color or of a sanguineous color. In secondary pleuritis, infection with pyogenic organisms may take place and then the fluid be- ; 31 32 CANINE MEDICINE AND SURGERY comes purulent, constituting the condition known as septic pleuritis or empyema. In primary pleur- itis the condition as a rule affects only one side of the chest, while in secondary pleuritis it affects both sides, but this is no hard and fast rule. The prognosis in primary pleuritis is generally favorable, though convalescence may be slow; that of the secondary variety depends entirely on the primary cause, or trauma. Symptoms.—Pleurisy may or may not be ushered in by rigors, but there is always malaise and great stiffness in action, and disinclination to move or bend the body, the condition being very painful. The respiratory movements are painful and almost entirely abdominal, the animal, on account of the pain attending thoracic movement, trying to fix the chest walls as much as possible. The constitu- tional disturbance is great, thirst is greatly in- creased, anorexia generally complete; the bowels are costive; the urine is scanty, highly colored, and contains albumin; the pulse is fast and wiry, the temperature 104 to 105 degrees Fahrenheit; the mucous membranes are congested. Until the effusion has taken place percussion yields negative results. Afterwards a dull sound is heard up to the level of the accumulated fluid. Auscultation reveals the characteristic friction sounds of pleurisy, or later the fluid may be heard splashing during respiration. Since the accumula- tion of fluid in the pleural cavity compresses the lung, sometimes to complete collapse, dyspnea is always well marked when effusion has taken place, and when the effusion is great symptoms of asphyxia manifest themselves; the compression of the heart and great blood vessels also leads to their . disturbed and impaired action. = tania PLEURISY 33 Where the effusion is great in amount the inter- costal spaces may be seen to bulge outward and the whole side of the chest is thus altered in ap- pearance. If empyema supervenes, the pulse be- comes rapid and weak, and the temperature is inter- mittent but always high. Sometimes, however, the first indication of the empyemic condition is the expectoration of pus or a pointing in an intercostal space; as the evacuation of the pus in empyema must not be delayed, every endeavor should be made to diagnose it early. If the presence of pus is at all suspected, an exploratory puncture should be made, Cough may or may not be present in pleurisy; ‘when present it is always painful, dry and sup- pressed. — Treatment.—At the onset of the disease there is hardly any drug that will combat the pain and fever and equalize the circulation better than aconite or its alkaloid aconitin. Either may be ad- ministered in small doses every fifteen minutes for two hours, and then hourly, until the effusion takes place. The tincture of aconite in two ‘minim doses, or 1-800 grain of aconitin, or a defervescent compound (aconitin, 1-800 grain; diditalin, 1-64 grain; veratrin, 1-128 grain), is perhaps the most useful. Aconitin, it must be remembered, is a. powerful drug, and its frequent administration must be stopped as soon as either the desired effect is pro- duced or the physiological action of the drug brought about, as manifested by the softening of the pulse, champing movements of the jaws, and general relaxation of the patient. When this has been attained the dose is given at longer inter- vals to maintain the effect. Counter-irritants should 34 CANINE MEDICINE AND SURGERY be applied to the thoracic walls, either in the form of cataplasma kaolini, or mustard or oleum sinapis, and a firm Supporting bandage placed around the chest to immobilize the ribs. The relief from pain given by thus fixing the ribs is most marked. When effusion has taken place, efforts must be made to hasten its reabsorption and_ elimination. This may be done by purgatives and diuretics. By their alterative and diuretic actions potassium iodid or ammonium iodid is of great service here. Codein in one-fourth grain doses, repeated as re- quired, will control the cough which, if present, is always distressing. Where the effusion is so exces- sive as to cause great difficulty in breathing, with symptoms of asphyxia, paracentesis thoracis should not be delayed, but promptly performed. The main danger lies in delaying the operation after the necessity for it is recognized, the patient’s vitality then not. being sufficient for it to recuperate. The after-treatment consists in protecting the animal from exposure to cold and wet, liberal diet, and a line of alterative and tonic treatment. Hydrothorax (Dropsy of the Thoracic Cavity) Hydrothorax, strictly speaking, is true dropsy of the chest, although the term has been loosely used in connection with the effusion found in pleurisy. Hydrothorax is a transudation, non-inflammatory in origin, and is the result of some other pathologic condition, such as cardiac or renal disease. Symptoms.—A gradual filling up of the thoracic cavity with the transuded fluid, with corresponding difficulty in respiration, is the usual symptom of hydrothorax. Percussion reveals a distinct level of the fluid in the cavity, parallel to the horizon. PLEURODYNIA 35 The normal respiratory sounds may be _ heard above the level of the fluid, and indistinctly or not at all below the level. Splashing sounds are also in evidence. The other symptoms will depend upon the primary condition. Treatment.—Treatment for this disease is usually unsatisfactory. It must first of all be directed to the primary disease, and unless this can be diagnosed and corrected the treatment of the hydrothorax can be only palliative. It consists in the exhibition of diuretics and in resorting to paracentesis thoracis. This operation is harmless and may be repeatedly performed to relieve the dyspnea, but as a rule gives no permanent relief unless the primary cause is curable. On the other hand, by its repeated per- formance the life of an old favorite may often be prolonged for a considerable time. Pleurodynia Pleurodynia is essentially rheumatism of the mus- cular walls of the thorax. This exceedingly pain- ful condition might possible be mistaken for pleurisy unless a careful examination is made. It is due undoubtedly to exposure to wet and cold, more especially in rheumatic subjects. Symptoms.—The animal is dull and listless, and evinces pain on movement and upon being handled. The breathing is shallow and abdominal, the patient trying to use his respiratory muscles as little as possible. When compelled to move, the animal shows great stiffness and disinclination to bend the body. The pulse may be a little more rapid than normal, but has not the wiry characteristic of the pulse in pleurisy. The temperature, as a rule, is about normal, or a little above it. Auscultation and percussion reveal nothing. 36 CANINE MEDICINE AND SURGERY Treatment.—Counterirritants to the affected mus- cles, capsicum linament or mustard, and the appli- cation of the padded pneumonia jacket should be resorted to. The region on.each side of the spine should be palpated, and spots tender to pressure should receive smart counterirritation. The patient should receive a saline laxative, such as one to four drams of magnesium sulphate, Its head being kept elevated for twenty minutes after its admin- istration to prevent’ it being vomited, and acetyl salicylic acid in doses of five to fifteen grains. Asperin (acetyl salicylic acid) is far superior to the ordinary salicylates, because it is soluble only in an alkaline medium and it does not cause the gas- tric disturbances that other salicylates cause. Bryonin, 1-20 to 1-40 grain, every two to six hours, will usually give prompt relief. In addition to the medical treatment, the patient must be kept in a warm, dry kennel and not ex- posed to cold or wet. The diet should be of a light and easily digested nature, such as milk, oatmeal porridge, or dog biscuit, while meat should be with- held until the attack is over. SCL bern ¥ DISEASES OF THE MOUTH, PHARYNX, AND ESOPHAGUS Stomatitis TOMATITIS, or inflammation of the buccal mucous membrane, is the result of either chem- ical, thermal or mechanical irritants, and is often a complication or symptom of some other disease or condition. It is also common during teething, and where there are decayed teeth. Symptoms.—The patient is observed to be slow and careful in eating, large pieces of food being discarded and smaller portions bolted without mas- tication. Salivation is a prominent symptom, the saliva hanging out at the corners of the mouth in glairy.strings. Upon examination the mucous mem- brane of the mouth will be found to be red, swollen, and inflamed, the amount of inflammation depend- ing on the cause. In the case of corrosive poisons having been taken into the mouth the mucous mem- branes may be greatly eroded and hanging in shreds, the gums and tongue are also inflamed and tender, and ulcers sometimes appear on different parts of the mouth. Treatment.—The dog’s diet must consist of bland and non-irritating liquids or mashes, such as soups, milk, beef tea, bread and milk, and boiled rice; plenty of cold water should be supplied constantly. The mouth should be kept clean by means of antiseptic and mild astringent washes, applied either with a camel’s-hair brush or an atomizer; decayed 37 38 CANINE MEDICINE AND SURGERY and loose teeth must be removed and the tartar cleaned from the remaining teeth. In teething, the inflamed gums may be lanced. Any of the following solutions constitutes a useful mouth wash for this ‘condition: 1. Potassium permanganate, one-per-cent solution. 2. Peroxid of hydrogen, one to five parts water. 3. Borax, 130 grains; sodium bicarbonate, 130 grains; carbolic acid, twenty-five grains; glycerin, five one-half drams, and water to make twenty fluid ounces. Ulcers may be touched with tincture of iodin or a strong solution of alum. The tender gums may be painted with a tincture of myrrh, or one part tannic acid to four parts glycerin. Stomatitis Ulcerosa, or Necrotic Stomatitis This condition is a necrotic inflammation of the mucous membrane of the mouth. It attacks the gums more frequently than other parts. Cause.—This serious condition is generally seen in old, debilitated dogs and in weakly, anemic, and pampered animals of all ages. It is usually associ- ated with decayed teeth, and is no doubt due to some microorganism, probably the Bacillus necro- phorus, or possibly to various organisms. It is possible that the “Black Tongue” of the Southern states is a modified (intestinal), type of this same infection. Symptoms.—The gums in the neighborhood of certain teeth become swollen, red, and painful to the touch. In a day or so there is marked increase of the swelling, and the affected gum is of a dark red, brown-red, or of a purplish hue, while the tis- sue affected is spongy, bleeds on the slightest pres- sure, and is seen to have receded from the teeth. Later, beginning with the swollen region next to STOMATITIS 39 the teeth, the affected part takes on a yellowish or greenish-yellow color. This necrotic tissue is of a pulpy, greasy consistency, and if removed, either by the sloughing process or by force, leaves a large ulcer about one sixteenth of an inch deep, with irregular, ragged edges. The walls of the ulcer are hard and hyperemic and raised above the general surface of the gum. As the gangrenous process proceeds, abscesses form in the alveolar process, and the teeth become loose and fall out; in extreme cases, the jaw itself may become necrotic and portions of the bone exfoliate. The morbid process extends from the gums to the lips and to the cheek, corners of the mouth, an in rare cases to the tongue. There is always a profuse salivation, the discharge being ropy, glairy, blood-stained, and of an intolerably fetid odor. There is usually a rise of temperature to 103 degrees Fahrenheit, or even higher if septic absorption takes place, in which case the patient usually dies of septicemia. The appetite is generally good, although mastica- tion is both painful and difficult. In cases that run a benign course the necrosis is usually confined to the mucous membrane, and after the separation of the slough, the ulcers heal rapidly, often being entire- ly well in from eight to ten days. In the case of old, debilitated subjects the disease more often assumes a malignant type, the gangrenous and necrotic proc- esses extend rapidly, and the animal dies from septic absorption. Treatment.—All loose and decayed teeth must first be extracted and abscesses evacuated. The mouth must be frequently swabbed with a deodorant mouth wash, such as potassium permanganate in one-per-cent solution or hydrogen peroxid, and after- 40 CANINE MEDICINE AND SURGERY wards strong disinfectants applied. Creolin in two- per-cent solution, painted on with a camel’s-hair brush, is most effectual. Lugol’s solution* of iodin applied in the same manner often gives good re- sults, and touching up the ulcers with caustics is also effective. Internally the patient should receive an occasional laxative and an iron tonic, Nuclein (eight minims hypodermically twice daily) should be given from the beginning of the treatment, and the animal’s strength kept up by a liberal and easily digested diet. Glossitis Inflammation of the tongue is usually the result of injury by foreign bodies becoming em- bedded in or lacerating the substances of the tongue. Among the common causes of this condition may be mentioned spicules of bone that become lodged between the molar teeth, elastic bands placed around the tongue either by children in play or by some malicious person, irritant medicines, and caustics, new growths (carcinoma, sarcoma), etc. Symptoms.—The animal shows difficulty in mas- tication and in lapping water. Salivation is pres- ent, the tongue is red, swollen,.and tender, and the breath is often offensive. Treatment.—A careful examination of the tongue must be made for foreign bodies, which, if present, must be removed. The teeth must also be examined for particles of bone wedged between them, and if any are found they must be removed. Wounds of the tongue heal with remarkable rapidity, and often the removal of the cause and the use of some mild antiseptic mouth wash complete the cure. *Lugol’s solution consists of: Iodin 5 parts; potassium iodid 10 parts; water q. s. 100 parts. EPULIS 41 Ranula Ranula is a large, fluctuating swelling which ap- pears at the lateral or under surface of the tongue, usually near the frenum. It is painful, produces profuse salivation, and may attain such size as to prevent the complete closure of the mouth. Cause.—This trouble is due to the blocking up or closure of the mucous gland and the consequent enlargement of the gland. An obstruction of Whar- ton’s duct sometimes produces a similar condition. The contents of ranule are of a thick, glairy, mucoid nature. Treatment.—This should be surgical, the instru- ments required are a mouth speculum, a_ small scalpel, scissors, and tissue forceps. The instrument having been sterilized by boiling for twenty min- ‘utes, the mouth is fixed open with a mouth specu- lum and the tongue drawn into such a position as to place the ranula in the most suitable situation for removal. The sac is then punctured with the scalpel and the whole of the wall dissected out; unless this is thoroughly done, the ranula will recur. After-treatment consists in washing out the wound three or four times a day with an antiseptic and astringent mouth wash. Boracic*acid, ten grains to the ounce, and chinosol, one-half*grain to the ounce of water, make useful antiseptic washes. Epulis This name is given to a hard, smooth, periosteal tumor which appears on the gums at the edge of the alveoli. There may be only one tumor, or they may be numerous, and may be benign or malig- nant in character. Unless these tumors cause pain and undue inconvenience in eating it is better not to interfere with them. If an operation is decided upon, they may be removed with a scalpel or scis- 42 CANINE MEDICINE AND SURGERY sors and the hemorrhage controlled by styptics. Occasionally a bony attachment may be found, in which cases bone forceps will be necessary to com- plete their removal. Papilloma or Wart Papillomas are often multiple, and may cover nearly the entire surface or the mucous membrane of the lips. Cause.—These tumors are of infectious origin. Treatment.—In many instances papillomas disap- pear spontaneously without treatment, and the ani- mal is immune against a second infection. Where they are very numerous, local applications of a satu- rated tannic-acid solution should be applied and Fowler’s solution given internally for at least a month before resorting to surgical means. If, how- ever, there are only a few tumors present, or the above treatment is futile, they may be removed by ligature or with the thermo cautery. It is best not to excise them with the scalpel or scissors, as the blood may infect a new area. Tumors of the Mouth The new growths met with in the mouth and pharynx of the dog are mostly carcinoma, sarcoma, and adenoma. Usually they are found affecting the ‘soft palate, the pharynx, and the vicinity of the tonsils, sometimes even invading the eustachian tubes. The cause of new growths is unknown. Symptoms.—At first the patient shows some diffi- culty in swallowing, and the appetite may be capri- cous. Upon examination the growth may be dis- covered or, if deep seated, an unhealthy looking ulcer with ragged edges may be seen. This may be mistaken for an injury caused by a bone or some other foreign body, but the involvement of the TEETH 43 neighboring lymphatic glands and the non-response to treatment in time reveal its true character. The diagnosis may be absolutely confirmed if a small portion be excised and submitted to an_ expert pathologist for microscopic examination. In all cases there is rapid emaciation, and sooner or later death relieves the sufferer. Treatment.—There is no successful treatment for this condition. Surgical interference appears to stimulate the malignant properties of these neoplasms, and the most humane course, once the diagnosis of malignancy is positive, is to end the animal’s suffer- ing by an overdose of chloroform. Harelip and Cleft Palate These congenital malformations may occur con- jointly or singly, and are serious defects. More especially is this true of the latter, as it is impos? sible for the puppy to feed in the natural way and it has to be fed from a feeding bottle with a nipple large enough to reach to the back of the mouth. A harelip “may be double or single. A.~cleft palate may be wide or narrow, existing either in the anterior or posterior portion of the mouth, or it may extend the whole length. Treatment.—The treatment is surgical, and con- sists of scarifying the edges of the lips or palate and uniting them by sutures. The details of this operation are given in Part II (see page 191). The Teeth The dog has forty-two teeth, formulated thus: i. 3-3 Ge 1-1) apm, 4-40 mi2-2 42 3-3 1-1 4-4 3-3 INCISORS CANINES PREMOLARS MOLARS JAW. Lip i i fs oe 1; Tis 1; Upper .....3 3 1 af 4 4 2 2 Lower ....3 3 1 il 4 4 3 3 44 CANINE MEDICINE AND SURGERY The first incisors and the canines, and the second, third, and fourth molars appear in the dog at the end of five weeks. The permanent teeth begin to appear about the third or fourth month; the canine and middle incisors about the fourth month, and the remaining incisors at the end of five months, as well as the second, third, and fourth molars, the fifth molar about five months, the sixth about the sixth month, and the seventh about the end of the seventh month. Then the dog has a “full mouth” at the end of the seventh month. During teething the gums become red and tender and the flow of saliva is increased. In some case3 the appetite may be entirely suspended and convul- sions may occur from reflex nervous irritation. In such cases the proper treatment is the administra- tion of simple sedatives, such as potassium bromid (five grains three times daily), and scarification of the gums. Tartar Tartar is a calcareous deposit on the neck of the tooth at the border of the gums. It is deposited chiefly around the canine and molar teeth, and causes great irritation of the gums, sometimes even loosening the teeth and giving the breath an offen- sive odor. ‘Tartar should be removed by scraping the tooth with a specially constructed instrument termed a “scaler,” the mouth either \being closed with a tape or kept open by means of mouth specu- lum. In powerful, violent patients a general anes- thetic may be necessary to facilitate the operation of removal. The teeth should then be cleaned with a toothbrush and camphorated chalk or other suit- able dentifrice. CARIES 45 Caries Dentum (Caries of the Teeth) True caries of the teeth—that is, molecular de- struction—is rare in the dog, but such cases have been observed. It begins on the upper surface and mainly in the cavity of the crown, appearing as a black spot. This spot, which is the decaying part of the tooth, gradually penetrates the tooth toward the pulp cavity, and finally exposes the nerve, tooth- ache being the result. In necrosis of the teeth there is usually an alveolar periostitis associated with it, the tooth becoming loose and yellow in color. In these cases alveolar abscesses may form and pyorrhea alveolaris, or dental fistula, remain. An animal affected with toothache becomes irritable, resents any manipula- tion of the mouth, has difficulty in mastication, and is salivated. The affected tooth is very tender; if struck with a sound or key causes the animal to cry. Treatment.—In true caries, if treated before the nerve is exposed, the tooth may be saved by care- fully drilling out the cavity, removing all diseased tooth substance, and filling the cavity with dental cement or amalgam. If, however, the case has gone too far for filling, extraction is the only remedy. For this purpose the mouth is held open by a specu- lum or gag, the forceps applied -as far on the tooth as possible, the tooth loosened by a few lateral twists and finally extracted by a strong pull in the direction of its roots. Immediately after the ex- traction the gums should be firmly compressed and the mouth washed out with an antiseptic lotion. 46 CANINE MEDICINE AND SURGERY Empyema of the Superior Maxillary Sinus Necrosis of the fourth upper premolar often leads to empyema of the superior maxillary sinus, into which its roots penetrate, the pus discharging by a fistula just below the eye. This fistula may heal for a time under an antiseptic treatment, but sooner or later the discharge is reéstablished. By the use of a probe and tapping the affected tooth the signifi- cance of the fistula is recognized. Treatment.—The fourth premolar must be ex- . tracted, the probe pushed down the fistula into the mouth, the sinus syringed out with an antiseptic, and free drainage maintained. The syringing 1s continued until healing takes place. Pharyngitis, or Sore Throat Cause.—Pharyngitis, or inflammation of the mu- cous membrane of the pharynx, may be caused by the extension or spread of inflammation from con- tiguous organs, by irritant medicines and chemicals, foreign bodies, or by injuries caused by unskillful attempts at removing obstructions lodged in the throat or in passing the probang. Symptoms.—Pharyngitis is manifested by a some- what stiff carriage of the head; difficulty in swal- lowing solids; sometimes by coughing, especially if laryngitis exists also, and by a congested appear- ance of the affected mucous membrane. Treatment.—The throat must be examined for foreign bodies, and if any are found they must be removed; this often presents considerable difficulty in the case of needles or pins, and great care must be exercised to avoid. breaking them. The throat should then be sprayed either with iodin solution, PAROTITIS 47 hydrogen peroxid, or Dobell’s solution of the fol- lowing formula: TENE TRIS: | 2S UR de hale Al ccd Cgc NOR ee tac Pik Cece ar De grs. 130 Sagi MICATMONALE |G 6. b. weiss aes wren crave’ grs. 130 Mie ITs OCR Leia LG UL perv cite vay a, ee lala «(os neh oiahe’ th abs) oes, gers. _ 25 PAGMOUIE ik eee le cee ee deer es eee sees fl. ozs. 5% MHC Mao FTL c eveh alate ofarais eka eke. aee ie Sieiee ietane’ os fl. ozs. 20. The diet must be restricted to liquids and soft foods to avoid irritation of the inflamed mucous membrane. Parotitis (Inflammation of the Parotid Gland—Mumps) Cause.—There are four varieties of parotitis (or parotiditis), the causes of which differ. Vhey may be classed as follows: Contagious parotitis, the specific organism of which has not yet been determined; traumatic parotitis, produced by injuries; metastatic parotitis, due to a metastasis of pyogenic organisms during attacks of distemper, pyemia, or septicemia; and parotitis caused by the extension of a neighboring inflammatory focus, as in pharyngitis, mastoiditis, or similar diseases. Symptoms.—In the contagious form the whole gland, or both glands, are swollen and tender, but there is no tendency to suppuration. In the other varieties the swelling is more circumscribed and suppuration usually takes places. The swollen glands are hot and tender and the act of swallowing is difficult and painful. Constitutional symptoms are fever, anorexia, and lassitude, while in sup- purative cases fluctuation is detected and the fever is usually high. Treatment.—The patient should receive a_ mild laxative—olive oil or cascara—and the affected glands, after being freely fomented with hot water, 48 CANINE MEDICINE AND SURGERY should receive an inunction of warm camphorated oil or have calaplasma kaolini applied. Moist heat in the form of Priessnitz compresses* often gives great relief by lessening the tension of the parts, and in cases where abscess formation is taking place it hastens the formation of the pus. Abscesses should be evacuated, drainage established, and the wound treated antiseptically. The diet must be of a liquid nature, such as beef tea, milk, and soft mushes. Foreign Bodies in the Esophagus, and Choking Choking is caused by the lodgment in the throat or esophagus of some foreign body, and is usually the result of greediness in feeding. The most com- mon foreign bodies are bones, gristle, needles, and pieces of wood. Symptoms.—The patient is greatly distressed, efforts at deglutition are greatly increased, and there is a return of food and drink through the nostrils. Treatment.—Sometimes the offending article may be forced back into the mouth by manipulation of the exterior parts, and in some cases extraction with throat forceps is easy; but in cases where neither of these methods is successful the probang must be *Describing the Priessnitz bandage or compress and its use, Glass says: “The object of the compress or bandage is to maintain-a con- tinual heat, either dry or moist, to certain parts of the animal's body. We first apply to the part affected a piece of absorbent cotton, thick wool, or dry felt; or if moisture is required, it is soaked in warm water or a medicated solution and wrung out to remove the excess of fluid; this is then held in position by a cov- ering, of some light material—a wide bandage of cheese-cloth is. the best—next a layer of oiled silk or rubber cloth (the object of this is to retain the heat and in case of a wet compress, the moisture), and finally over this is placed a compress or bandage of flannel. This last is to prevent loss of heat by radiation. Some- times the inner layer of cheese-cloth is omitted, or it may be put on the outside of all. > “The above procedure may seem to the hurried practitioner a rather long,and unnecessary method, but after one has tried it and found the great advantages it has in the retention of heat, especially in diseases of lungs, in hastening the maturing of an abscess, or in the lessening of a _tumefaction by the constant and direct application of heat and moisture, he will realize its benefits,” So a es ie PAROTITIS 49 passed and the offending body cautiously pushed on-to the stomach. In the case of fish bones or needles the operator may be able to entangle them in the horse-hair portion of the probang and ex- tract them. Great caution must be exercised not to use undue force or the esophagus may be ruptured, with seri- ous, if not fatal, results. Fuller directions for pass- ing the probang and for esophagotomy are given in-Part II, Section II (see page 192). 5 EAC A Ne Sana DISEASES OF THE STOMACH AND INTESTINES N the dog, impaction of the stomach and gas- tritis constitute about sixty per cent of all dis- eases of digestion. This is due mainly to the want of proper attention to the animal’s diet and to the practice of feeding only once a day, whereby the animal seeks to satisfy its hunger in a voracious manner. Impaction of the Stomach Cause.—Overfeeding and improper food are the principal causes of impaction. Symptoms.—Vomiting is an evidence of this trou- ble, and if it takes place may empty the stomach and so relieve the condition, but in the majority of cases vomiting is not violent enough to give much relief, and the patient will retch, slaver, and eruc- tate gas. Pressure over the epigastric région pro- duces pain, the respirations are accelerated, and the patient is greatly depressed. There are colicky symptoms, with ‘great uneasiness and a_ frequent: desire to change positions. The animal groans or whines, and may be irritable and “snappy.” Treatment.—Empty the stomach by a hypodermic injection: - of 4-20. to. 1-10 grain. “ot apomorphin. Enormous masses of undigested or partially di- gested food are usually vomited, and relief is almost instantaneous. The stomach may then be washed out by means of the stomach pump, or eight to ten ounces of water may be administered and the 50 GASTRITIS ; 51 dose of apomorphin repeated to more thoroughly clean the stomach. A_ gastric sedative, such as from five to twenty grains of bismuth subnitrate, may then be administered and the animal’s diet restricted for a week or longer to small quantities of easily digested food. Gastritis This ailment, due to inflammation of the mucous membrane of the stomach, occurs both in the acute and the chronic forms. Acute Gastritis Cause.—Acute gastritis is caused by irritating foods or medicines, such as decomposing meat or arsenic, corrosive sublimate, or phosphorus, as well as by foreign bodies. Acute gastritis also occurs as a symptom of distemper. Symptoms.—There is vomiting, with little or no appetite, and increased thirst, great quantities of water sometimes being taken, only to be immedi- ately vomited. There is more or less constipation. The temperature is raised and the pulse accelerated. Pressure on the stomach causes pain. The patient is greatly depressed, lying down a great deal and assuming an almost diagnostic attitude, by trying to rest its abdomen on the floor. Treatment.—If an irritant-poison, decayed meat, or a foreign body is suspected to be the cause, an emetic should be administered to clean out the stomach. The vomiting may be controlled with from five to twenty grains of bismuth subnitrate, combined with three grains of cerium oxalate or five grains of chloretone. The constipation may be overcome ‘by laxatives and enemas. If the pain 52 CANINE MEDICINE AND SURGERY indicates it, morphin in one-fourth-grain doses’ may be given subcutaneously, but chloral hydrate must never be used on account of its irritating effect on mucous membranes. .In cases where there is _ex- cessive tenderness on pressure, warm fomentations or turpentine stupes, or even the application of mus- tard over the epigastric region, often afford great relief. The animal must be kept on a low diet for some days; equal parts of milk and lime water may be given, and beef tea or finely minced, raw beef in small quantities. The after-treatment consists of a stomachic, such as a combination of quassia and strychnin, or tincture of rhei and tincture of nux vomica. Chronic Gastritis This disease is often the sequel to repeated at- tacks of the acute form; it may appear also as a secondary complication in other diseases. Gen- erally, however, it is the result of continued im- proper diet, associated with a debilitated state of the system. Symptoms.—Evidences of chronic gastritis are somewhat similar to those of acute gastritis, with the difference that the appetite is not entirely lost but is extremely capricious. Vomiting comes on only after eating, and there is no fever, and seldom is there evidence of pain on pressure over the epigas- trium. The patient gradually becomes emaciated. Treatment.—Constipation or diarrhea must be cor- rected at the outset and the diet previously indi- cated for acute gastritis prescribed. Internally a combination of two grains of pepsin, two and one- half grains of bismuth subnitrate, and 1-100 grain of strychnin may be given immediately after meals GASTRITIS 53 three times daily, followed later with an alterative and tonic mixture such as: K BUTEA PTINIGIS WOT CH rn) 2) aioe ai etal aesbat (eta aicys's drs. 4 SATO Me ACTON “ULSCNIOSL< ste is <1 vues ave tre.eva's 3/0 drs. 1 CUA gad 23) 00 PG Sa ae oe oz. 1 Ray beme CLINE UIT DAN Serene oreiss) avatars feteee aharer suste’s OVAS sal PNCIRISE RMN Sela are ans Sig.c\ Sista stone eieta see ei ste aus, oe ozs. 4 M. Give two drams three times daily. Or Kk AG RironyaTOCHlOTICH <2 5 cok 6 sc eels a's drs. 2 iret OL Lalies. COMM eta sis ceeds feiae Ga ves ete oz. 1 SHVIR DARD cha) tle ee en eae ae oz. 1 /NCUTTIEESM (0 ae Kc pea Ro CG ne a PAPO ate eC ozs. 4 M. Give one dram three times daily, after meals. The diet must be carefully regulated to avoid a recurrence of the trouble, the animal being fed small quantities at a time and several times daily. Proper exercise, grooming with a hound glove, and sanitary surroundings are valuable aids to treat- ment that are frequently overlooked. Foreign Bodies in the Stomach The variety of substances which may be swallowed either intentionally or accidentally while at play is so extensive as to prohibit a coniplete list; but sticks, stones, pins, needles, bones, coins, rubber balls, and corks are among those generally met with. Symptoms.—In many instances the patient shows no ill effects unless the foreign body either perfo- rates the stomach or, passing on, blocks the in- testines. Silver coins may remain in the stomach for years and cause no illness whatever, but copper coins undergo corrosion in the stomach or intes- tine and in time cause serious illness or death. In the case of pins, hat pins, and needles, their pres- ence in the stomach is often unsuspected until an abscess forms either in the esophageal region, be- 54 CANINE MEDICINE AND SURGERY tween some of the posterior ribs, or in the flank. The history of the case should be obtained and the habits of the animal inquired into, to determine whether the patient has actually been seen to swal- low something, or is in the habit of picking up and swallowing odds and ends. The most prominent symptoms are attempts at vomiting, poor appetite, general dullness and depression, irregularity of the bowels, blood in the feces, general unthriftiness, and emaciation. An examination with the Roentgen rays makes the diagnosis more positive. Distemper HIS is the most widespread, the most common, the most fatal, and with the exception of rabies the most dreaded malady of dogs. When first dis- covered in France, from which country it was im- ported into Great Britain, it was and is still named distemper, yet that name seems unhappily chosen as being too indefinite for correct application to a disease marked by such varying phases. Distemper is also known as “dog.ill”. in some parts of Eng- land, and the Scotch term it “the snifters.” This latter term, although unscientific, certainly graphi- cally conveys to the mind one important character- istic of the disease, namely, the snifting noise— half-cough, half-sneeze—made by the dog in _ his efforts to get rid of the exudate which accumulates in the upper air passages; but “snifting” is a term too limited to adequately describe a disease which has well been called the “scourge of the kennel,” and which assumes so many forms and complica- tions. Etiology.—Until quite recently the causative agent of this disease was simply a matter of specu- lation, many theories being advanced as to the etio- logical factor. The microdrganism now definitely determined as the sole cause of distemper is the Bacillus bronchisepticus*, discovered and isolated in pure culture by Dr. N. S. Ferry. Although respon- sible for the primary symptoms of the disease, the Bacillus bronchisepticus is by no means responsible *Many able observers have been unable to verify the findings of Ferry, and the causative factor in canine distemper may be said to be unsettled in the minds of many bacteriologists, not a few of whom believe the agent to be a protozoan, 148 DISTEMPER 149 for the complications which generally ensue during the course of the malady. There are always closely associated with it the various strains of Staphylo- cocci and Streptococci, and it is the effect of their combined toxins that gives us the clinical picture which an animal presents when sufferirig from dis- temper. Among the predisposing causes of dis- temper may be mentioned youth, unhygienic sur- roundings, in-breeding, in fact, any circumstance which tends to lower the animal’s vitality and its powers of resistance to disease or unfavorable con- ditions. Symptoms.—The symptoms of distemper vary considerably according to the particular local com- plications which are developed; they are also de- pendent upon the severity of the attack, the powers of resistance of the patient, the rapidity with which the disease progresses and the treatment the pa- tient receives. As a rule, the first observable symp- toms are pronounced lassitude and dullness, a great disinclination to play or exercise, a decided prefer- ence for warmth, the dog creeping into’ the warm- est corner or crouching before the fire, and a gen- eral languor that appears to benumb the dog’s ener- gies; so that the hitherto lively dog, instead of jumping with delight at his master’s call, merely replies with a spiritless wag of his tail and a dis- mal, woe-begone look. Loss of appetite is an in- variable symptom and_ feverishness ensues, as shown by the hot, dry nose, rigors, and by the clinical thermometer; considerable thirst is present; the bowels are generally deranged, sometimes re- laxed, sometimes constipated; the urine is scanty and high-colored; the coat is usually rough and staring; retching and vomiting often oc- cur; there is a thin, watery discharge from the nose and eyes, and a hyperemic condition of the 150 CANINE MEDICINE AND SURGERY conjunctive; and the eyes appear unusually sensi- tive to light. A short, dry, husky cough and sneezing occur, especially when the animal is brought into the open air. ‘The discharge from the eyes and nose gradu- ally becomes more purulent, sticking the nostrils and eyelids together, causing the patient much dis- comfort and inconvenience and interfering with respiration, and resulting in constant efforts to clear the nostrils which produce that peculiar noise that has earned for the disease the popular name above mentioned. In many cases the eyes are seriously affected. A small bluish-white opacity may be observed which gradually widens and deepens until an ulcer is formed. This ulcer, which, by perforating the an- terior layers of the cornea, may cause the con- dition known as staphyloma or may even allow the aqueous humor of the eye to escape. Such cases, although of alarming appearance, usually do well under appropriate treatment, although in some cases of extreme severity some slight opacity of the cornea may remain. As the progress of the disease advances, special symptoms present themselves, de- pending upon what -organ or organs are chiefly involved. However, a constant and unvarying symptom in all cases of distemper, irrespective of local complications, is rapid emaciation and loss of strength. In cases where the respiratory tract is chiefly involved the symptoms of bronchopneumonia pre- dominate. When the digestive tract is the subject of serious invasion, digestive disturbances are em- phasized and there is vomiting, profuse watery and offensive diarrhea, and in many instances an icterus. When the central nervous system is_ involved DISTEMPER 151 symptoms of cerebral congestion, accompanied by convulsions and sometimes by attacks of mania closely resembling those of rabies, make their ap- pearance. Again the patient may become partially or eyen completely paralyzed, or it may develop the persistent clonic convulsion of some group or groups of muscles, known as chorea. In distemper the skin, especially that inside the thighs, on the chest, and on the belly, is often the seat of a pustular eruption (the exanthema of dis- temper). These pustules discharge their contents, dry up, and form scabs. The scabs later on fall off, leaving small depigmented areas. The significance of the appearance of this exan- thema is still a debated question among practition- ers, some contending that it foreshadows a fatal termination, others that its appearance is a favor- able symptom. The author’s experience is that it is merely a manifestation of the disease and has no significance either one way or the other. Another prominent symptom in distemper is the characteristic and exceedingly offensive odor ema- nating from the patient’s exhalations and from the skin, the latter also having a peculiar greasy feel to the touch which can hardly be mistaken when once experienced. Treatment.—The therapeutic indications for dis- temper vary with the particular complications the case presents. ‘In other words, symptoms must be treated as they arise, but. the whole rationale of treatment may be summed up by saying that the patient’s powers of resistance must be raised to resist the invading organisms, and free elimination must be established to carry off both the microbic toxins and those toxins produced by the normal flora of the intestinal canal, which in disease are 152 CANINE MEDICINE AND SURGERY absorbed into the system because of imperfect elimination and perverted metabolism. Thus we have to deal not only with the toxemia produced by the primary invading organism, but also with the condition known as autointoxication or auto- toxemia. . Elimination may be secured by medicines caus- ing free evacuations of the bowels and by those stimulating the free excretion of urine. To obtain the former, a dose of calomel should be given, preferably in repeated small doses to effect; the latter may be attained by appropriate doses of such diuretic medicines as spirits of nitrous ether, potas- sium nitrate, potassium acetate, or potassium citrate. In addition to this cleaning-out process, the flora of the alimentary tract must be kept under control by the use of intestinal antiseptics, such as calcium creosote, the sulphocarbolates of zinc, calcium, and sodium advantageously combined with a_ bismuth salt, acetozone, (fifteen grains to the quart of water and given ad libitum in the drinking water), creo- sote, or salol in enteric-coated pills or capsules. To raise the patient’s powers of resistance a bacterin composed of Bacillus bronchisepticus com- bined with Staphylococcus, aureus and albus, must be administered hypodermically every three days in ascending doses. The action of the bacterin treat- ment is much increased, especially if the patient has not come under observation until the disease is well advanced, if a simultaneous hypodermic in- jection of nuclein is administered. The respiratory complications must be treated as they arise, under the directions given previously for handling respira- tory diseases (see pp. 12-30). DISTEMPER — 153 A useful combination for general routine of cases is as follows: Paes er OME TONING | ass, 0.5 a er arajcla Ghee Syetewe aisles aa © oz. liss Semele SOLD: 5 ps onde oaivis Co 8 s'w ove « oz. iiss PeiSelWE CLITALE recis occulorum, when affected by spasm, cause the eyes to retract within their orbits and the membrana nictitans to protrude over the eyeballs. The whole body becomes rigid; the extremities stiff and stilt- like, the neck outstretched, and the tail elevated. Breathing is interfered with by the spasm of the inspiratory muscles. Depending upon which group of muscles is mainly affected, the patient’s body assumes various positions when the spasms are present. The head and tail may be elevated and the back depressed; the back may be arched and the abdomen tucked up; or the body may be curved laterally. The tem- perature is at first only moderately elevated, but in cases approaching a fatal termination it may | 160 CANINE MEDICINE AND SURGERY reach 108 to 110 degrees Fahrenheit and continue to rise for some time after death. The prognosis should be guarded. As a rule it is slightly more favorable in the dog than in the horse. Treatment.—Good nursing and the avoidance ot all excitement and noise are essential. The patient should be placed in a darkened room and kept ab- solutely quiet, as on account of the extreme irrita- bility of the nervous reflexes the slightest sound or movement may induce or aggravate the spasms. Nerve sedatives are the drugs indicated, in order to endeavor to control the spasms, the most valu- able being gelsemium and lobelia. In exceptionally acute cases chloroform combined with H-M-C in full doses must be used to induce complete anes- thesia in order to relax the patient. It must @he remembered that to produce the desired effect te- tanus patients require doses far in excess of those usually administered, and that these drugs may be pushed with safety. Elimination per anum and through the kidneys must be provided for, and enemas of predigested milk or beef given to sustain life, if the patient is unable to eat. Tetanus antitoxin is useless as a curative, but as a prophylactic is of undoubted benefit if ad- ministered before the appearance of symptoms. Anthrax Anthrax is an infective disease caused by the Bacillus anthracis. Young dogs are extremely sus- ceptible to anthrax, but mature animals appear to develop a comparative immunity. Eating meat con- taining anthrax germs is the usual cause of the disease in the dog. On this account the animal ordinarily suffers from the intestinal form of the TUBERCULOSIS 161 disease and from local anthrax of the mouth and pharynx. It must be remembered that the blood of an in- fected animal is the medium of infection and also that while the bacilli themselves are comparatively easily destroyed, that the spores are extremely re- sistant to the action of disinfectants. The gastric juice has no effect upon the spores of anthrax, although it is bactericidal for the bacilli themselves. Symptoms.—Suddenness of attack, high fever, dyspnea, violent intestinal disturbances, hemorrhages from all the natural openings of the body, the local manifestations in the mouth and pharynx—saliva- tion, the presence of vesicles on the mucous mem- brane, swelling of the throat, cyanosis, are all indicative of this disease. The diagnosis is com- pleted by the microscopical examination of the blood and the identification of the Bacillus anthracis. Treatment.—Needless to say, suspected cases should be handled with extreme caution, as the disease is communicable to other animals and man. All blood and discharges should be carefully dis- infected and the carcasses should be cremated. At- tempts to cure the patient are futile. Tuberculosis Tuberculosis is not a common disease of the dog, but cases do occur and such can nearly always be traced to infection from mankind. It has been amply proved that the patient becomes infected by inhaling the dust from a room inhabited by a tu- berculous person, or by licking up tuberculous spu- tum or from eating food from the plate of a person affected with tuberculosis. Symptoms.—Usually the disease assumes the as- pect of a chronic pneumonia or a chronic bronchial 162 CANINE MEDICINE AND SURGERY catarrh, quite unyielding to treatment. The tem- perature is fluctuating, there usually being a rise towards night. There is often weakness and a rapid, progressive emaciation. Auscultation reveals areas of dullness, the presence of cavities, rales, suppressed respiratory murmur and so on. Diagnosis is assisted by the history of the case and a knowledge of the owner’s state of health. It may be confirmed except in advanced cases by the tuberculin test. Treatment.—Owing to the danger to human _ be- ings, treatment should not be attempted. The pa- tient should be sent to the happy hunting grounds immediately. Granuloma This is a disease of true infection, a venereal dis- ease of dogs, affecting chiefly the mucous mem- brane of the vagina and of the penis and prepuce. It is transmissible by coition and by inoculation. Cause——The causative agent is unidentified as yet. Symptoms in the Female.—Although the lesions are usually confined to the genital organs, other parts of the body may become affected in conjunc- tion or independently. The lesions are generally found on the skin of the neck, throat, back, groin, abdomen and limbs. Metastatic growths are also often found in the abdominal and mesenteric lymphatic glands, kid- neys, spleen, liver and lungs. In the genital organs of the bitch the lesion gen- erally begins as a circumscribed swelling of the mucous membrane, deep red in color and by a grad- ual elevation of the tissue and develops into round nodular sessile tumors, these become lobulated, pre- senting a warty and cauliflower-like appearance. INFECTIOUS, GRANULOMA 163 These growths are friable and bleed freely upon the slightest manipulation. They are most commonly situated in close prox- imity to the urethral opening. The presence of these- infective venereal tumors is usually unsus- pected until a sanious, muco-purulent discharge is - noticed at the vulva, when an examination reveals their presence. In severe cases the whole vagina may become blocked up, rendering coition painful and parturition impossible. After about three months retrograde changes take place in the tumors which break down and disappear but invariably leave the vaginal wall inelastic by reason of cicatricial contraction, so that if numerous parturition is attended with grave dif- ficulties. Treatment.—The growths should be removed by dissecting them off the vaginal walls, their bases freely curretted and painted with tincture of iodine. Hemorrhage is easily controlled by packing the vagina with aseptic gauze. Symptoms in the Male.—Hemorrhage after co- ition, refusal. to serve and sometimes difficulty in urination (if the growth involves the urethral open- ing) should lead to an examination for venereal warts. Exposing the penis by drawing back the prepuce of course reveals the condition. In the male the infective tumors, in the early stages of the affection, appear as small yellowish- white raised patches about the size of a mustard seed. Later on the growths take on the character- istic cauliflower-like appearance and bleed readily when touched. They may be situated at the ex- meme vendor the ,penis; wpon the sides. or at its base. Treatment.—Secure the patient in the dorsal po- 164 CANINE MEDICINE AND SURGERY sition and then fill prepuce with a five per cent solution of cocaine. After waiting ten minutes to allow the parts to become properly anesthetized, expose the penis, pick up the growths with rat-tooth forceps and snip them off with sharp scissors, cut- ting well into the surrounding healthy tissue. The resulting wound should be treated antiseptically and, if extensive, sutured with fine silk (No. 00). ue CATT Ori, ae OX INTERNAL PARASITES AND PARASITISMS ONTRARY to the popular belief, intestinal parasites, unless the infestation is particularly heavy, do not cause any very serious constitutional disturbances. However, large numbers of parasites, especially in puppies, may give rise to alarming symptoms and in some instances even cause death. Intestinal parasites are detrimental to their host by reason of the irritation they produce, their in- terference with the digestive process, the deleterious effect of their waste products, the abstraction of blood, or by mechanical obstruction. We may, therefore, look for a definite train of symptoms when the infestation is heavy. The general symptoms of parasitism are a general unthrifty condition of the patient—a rough, dry coat, appetite variable but usually voracious, anemia, gradual emaciation and alternate constipation and diarrhea. Convulsions are common and in certain special cases there is bleeding from the nose. Pru- ritus ani is well marked in cases where the parasites inhabit the rectum. The diagnosis, however, 1s positive only when the parasites or their ova are detected in’ the feces. Notwithstanding the com- parative harmlessness of parasitism to the patient itself, every means should be employed to rid him of these pests and to destroy their ova and thus prevent their reproduction, on account of the danger from some of them to both man and other animals. Of these Tzenia echinococcus and Tzenia ccenurus are examples producing respectively hydatid disease 165 166 CANINE MEDICINE AND SURGERY in man and “gid” in sheep. Only brief reference to the morphology and life history is given here, the student being referred to the standard works on parasitology for more detailed information. Spiroptera Sanguinolenta This parasite is a small, round worm that 1in- habits the walls of the esophagus and stomach. The intermediate host is the Blatta orientalis. This nematode worm is readily recognized by its blood- red color, and in addition to its normal habitat as stated above, it may be found in the aorta, lungs, and lymphatic glands. Its presence in the esophagus and stomach forms tumors consisting of indurated tissues in which there are chambers containing the rolled-up worms. Symptoms.—Repeated vomiting and rapid emacia- tion give evidence of infestation by this parasite. Sometimes, too, there is rabiform convulsions. Ascaris Marginata The Ascaris marginata is a nematode worm, the male from five to ten centimeters long, the female from nine to twelve centimeters long. In color it 1s white or reddish white. These worms are more especially common in puppies, who may be infested with them at three or four weeks old, but it 1s at the age of three or four months that they are most abundant. Their habitat is the small intestine and frequently the stomach. Symptoms.—Unthrifty coat, emaciation, enlarged abdomen (pot-belly), variable appetite, sometimes convulsions, colics, and constipation or diarrhea re- sult from infestation by this parasite. By collecting in rolled-up masses the parasites sometimes cause complete intestinal obstruction, which is followed by death. In one case in the author’s practice the PARASITES 167 stomach and intestines of a month-old puppy were found on‘ postmortem examination to be tightly packed with worms, which, when removed, com- pletely filled a six-ounce bottle. Treatment.—All solid food must be withheld for twelve hours, when capsules containing calomel and santonin, one-half grain of each, should be admin- istered every three hours until purgation takes place. The following prescription has given complete satis- faction to the author in numerous cases: i Fluidextracti spigelia, PuMigextracti SMM, AA .8 6... sisi ote ues OVAR Sig.—Give 15 to 30 minims every morning until three doses have been given. There are many other vermifuges applicable, but whatever one is used, a laxative should either be combined with it or administered after the last dose, and in every case of worm infestation the treatment should be repeated every two weeks until the feces show no evidence of parasites or of their ova. All feces of infected dogs should be burned to prevent other animals from becoming infested. Oxyuris Vermicularis This is a small, white, thread-like worm, the male from two to three millimeters long, the female from nine to ten millimeters long. These parasites in- habit the rectum and cause considerable irritation and anal pruritus; the patient continually drags the anus along the floor to relieve the itching. Symptoms.—Anal pruritus and the presence of the parasites in the feces prove the presence of the parasite. Treatment.—A laxative should be administered, followed by enemas of a saturated solution of sodi- um chlorid or a strong infusion of quassia chips. 168 CANINE MEDICINE AND SURGERY Ankylostomum Trigonocephalum The hookworm is white in color, the male from nine to twelve millimeters long, the female from nine to twenty-one millimeters long. These para- sites inhabit the small intestines and produce grave symptoms. They are true bloodsuckers, producing pernicious anemia. Symptoms.—The symptoms are those of grave anemia—a gradual but progressive emaciation, and debility. The appetite is unaffected at first, but later on becomes capricious and finally disappears. The coat is staring, the skin scaly and dry. The nose is tumefied and becomes excoriated with the mucosanguinolent discharge. Later) a . copioas epistaxis supervenes, two or three ounces of blood being lost at each attack. These attacks of epis- taxis recur at intervals of a few days to several weeks, during which the mucosanguinolent dis- charge continues. In some cases convulsions occur. Intermittent edematous swellings make their appearance on the limbs, which finally become permanently edematous. In the last stage there are ulcerations, gangrenous patches, and persistent diarrhea, which may give place to dysentery. The course of this condition is extremely chronic, the animals lingering for months or even a year. Treatment.—When pernicious anemia appears in a pack of hounds extreme care should be taken to thoroughly clean and disinfect the kennels. The sick should be isolated and prevented from soiling the drinking troughs, they should be ted and watered in individual utensils which should be boiled immediately after use, and their feces should be burned. The anthelmintic which has been proved to be PARASITES 169 of the greatest service is thymol given in large doses and followed up by a saline laxative. Oil ct male fern is also very effectual. This latter should be given only after the patient has been fasted for twenty-four hours, having previously received a purgative. Six to eight hours after the exhibition of the male fern a saline purgative should be given to clean the intestinal canal. The strength of the patient must be carefully maintained by nutritious and easily digested foods—milk, and raw meat— with tonics of iron and a bitter tonic such as quas- sia or gentian. Tricocephalus Depressiusculus A white worm forty-five to seventy-five milli- meters long. This parasite inhabits the cecum of the dog and is often found in conjunction with the Ankylostomum trigonocephalum. It produces anemia and often typhlitis—appendicitis. Treatment.—The same as for Ankylostomum trig- onacephalum. Tznia—Tapeworms The tapeworms most commonly. met with in the dog are merely mentioned here and the reader is again referred to works on parasitology for a more extended description. The fcliuwing table gives the name, the intermediate host, and the larval form: NAME LENGTH INTERMEDIATE Larva Form ; Host Tenia Serrata....}50 cm. to 2 m...}Hare and rabbit..|Cysticercus pisi- formis Tenia Serialis....]45 cm. to 75 cm.]Rodents ........ Ceenurus serialis Tenia Marginata. PeBaeW tO. Ay tite phe | CEMA ATTES: Wotecs «las Cysticercus tenui- collis Tenia Coenurus..|so cm. to 75 cm.|Sheep ..........- Ceenurus cerebralis T. Echinococcus../4 mm. to 5 mm..}]Man, swine, rumi- STATES si atisia ah «eines Echinococcus poly- é . morphous Msria | CARS sc eee. to cm. to 40 cm.}Louse and flea...|Cryptocystus trich- odectis Aretiial ISEADPENs, «-eclfits ‘Liles wa/State wieie air Remdeer «2. sys 0 Cryptocystus serra- ticeps 170 CANINE MEDICINE AND SURGERY Of these tapeworms the most important from an economic standpoint are the Tenia echinococcus and the Tzenia ccenurus, the first producing hydatid disease in man, the second “gid” in sheep. The symptoms of tapeworm infestation are those of general parasitism, and the diagnosis is positive when the segments are found in the feces. Treatment.—After thoroughly preparing the ani- mal by fasting and laxatives, administer on an empty stomach fifteen minims to one dram of oil of male fern, followed in eight to ten hours by a saline cathartic in full doses. The expelled para- sites should be carefully examined to ascertain if the head has been expelled, and if not the treatment should be repeated in ten days. The same precau- tions as to burning worm segments and the bowel discharges must be taken as mentioned before in this section. ai CP LO Nox AT POISONS AND POISONING OISONING in the dog may be accidental or intentional. The former may come about by the animal picking up poisoned meat or other food laid down for vermin, or the patient may ,show symptoms after an overdose of some drug given empirically. Some animals show a great suscepti- bility to the action of some drugs, notably strych- nin, symptoms of poisoning appearing after even moderate medicinal doses. Poisons cause death 1. By their corrosive or tissue-destroying proper- ties ; 2. By their physiological action; 3. By a combination of (1) and (2). Poisoning in canine patients, whether intentional or accidental, is only too often fatal, the quantity of the drug ingested in nearly every case being large and the patient’s condition often not discovered until irreparable damage has been done. The usual portals through which poisons are absorbed are the respiratory and digestive system, with air or food. Occasionally they are absorbed through wounds in the skin. Pathology of Poisoning Local Effects.—These are the results of the action of the poison on the living cells with which it comes in contact and consist of more or less violent irritation, varying in degree from congestion or in- flammation to mortification, and these local effects react on the whole system, giving rise to fever, col- lapse, and other serious conditions. 171 172 CANINE MEDICINE AND SURGERY Absorption.—The rapidity with which poisons are absorbed depends to a great extent on the poison itself, the portal by which it gains entrance to the animal’s economy, the condition of the diges- tive tract—wnether full or empty, and also the nature of the stomach contents. For instance, the unbroken skin will easily and rapidly absorb gases, but solids or liquids hardly at all; on the other hand, irritated or woundea skin becomes very ab- sorbent. Again, an empty stomach will absorb far more readily and rapidly than a full one, and yet again, the digestive tract just after a imeal of fatty substances, even milk, is far more impene- trable than when a meal with no fat has been par- taken of. The exception to this is phosphorous, the absorption of which is accelerated by oils and fats. Elimination.—Poisons are eliminated in the excre- tions. Nearly all mineral poisons are eliminated through the kidneys, some by the bowels. Gases, vapors, and volatile poisons are eliminated by the lungs. Some poisons undergo changes during elimi- nation, others are eliminated unaltered. Treatment.—The main objects to be attained are to delay or prevent absorption, to neutralize the poison or render it insoluble, to eliminate from the system both what is absorbed and what is unab- sorbed, and to counteract the effects produced by the poison absorbed and the resulting lesions. The first can be accomplished by emetics and purgatives, the former by reason of their rapidity of action being the most valuable. Purgatives are chiefly valuable when combined with agents that retard absorption or with those that unite with poisons and form insoluble or inert compounds. Antidotes act in three ways: they neutralize the poison, render it insoluble, or arrest its injurious effects. —————<— POISONING 173 Arsenic Arsenic, or rather arsenious acid (arsenic trioxid), is one of the commonest of vermin poisons, and dogs are frequently poisoned on that account. Dogs may also become poisoned by the arsenic in an overdose of Fowler’s solution given for medicinal purposes. The toxic dose of arsenic is two grains. Arsenic is a corrosive irritant, producing gastroenteritis, with its corresponding effects. Arsenical poisoning may be either acute or sub- ° acute. Symptoms of Acute Arsenical Poisoning.—About an hour after ingestion there suddenly appears profuse salivation, swallowing movements, and great thirst. The patient is restless and anxious, with convulsive action of the lips, acute colicky pains, and vomiting. There is great pain over the ept- gastric region, and intolerance to pressure. At first there is constipation, which later on gives way to a fetid dysentery. The pulse at first is full, but soon becomes small, irregular, and impercepti- ble; respiration is difficult, urine scanty and often bloody, and the temperature is subnormal and the extremities cold. Later on rigors set in, with weakness and paresis, the gait is staggering, the pupils dilated. The pain is excruciating, and the animal dies in a state of collapse in from four to five hours. Symptoms of Subacute Arsenical Poisoning.—There are much the same as in the acute form, but not sQ@ violent. There is dryness of the mouth, great thirst, colicky pains, vomiting, fetid diarrhea, and tympanites. The mucous membranes are _ pale, the pulse irregular but frequent, the urine scanty. These symptoms may persist for about twenty-four 174 CANINE MEDICINE AND SURGERY hours, when the patient seems to improve. This improvement, however, is_ short-lived, the patient soon relapsing and becoming worse. There is great depression and weakness and he is unable to stand. Dyspnea is present, and the pulse is weak and almost imperceptible. Convulsions may occur, or the patient may lapse into coma. There may be edema of the eyelids and dependent parts; paralysis of the hind quarters then sets in, and death fol- lows in a day or two. Treatment.—Administer an emetic, 1-20 to 1-10 grain of apomorphin, and follow with an antidote. Antidote: Sesquioxid of iron prepared by pre- cipitating tincture of iron perchlorid with an alkali. Large amounts of this antidote should be given every twenty minutes or so, followed up by a purgative of magnesium sulphate. Three ounces tincture of iron perchlorid, and one ounce of sodium carbonate, dissolved in water and mixed together, will produce sufficient sesquioxid to neutralize ten grains of arsenious acid. Insoluble arsenate of iron is formed and is swept out by the magnesium sulphate. In acute cases hypodermic injections of morphin every half hour will retard absorption and ease pain. Later on and in subacute cases, opium com- bined with a demulcent has the same effect and tends to soothe the inflamed mucous surfaces. Fo hasten elimination, spiritus etheris nitrosis should be given in full doses, well diluted with water. Collapse must be combated wth stimulants. Phosphorus Phosphorus poisoning in dogs is usually acci- dental, and due to their picking up pieces of bread or meat smeared with vermin paste of which phos- phorus is the chief constituent. Symptoms.—The first symptoms of phosphorus POISONING 175 poisoning generally appear about an hour after the ingestion of the poison, manifestations of acute gas- tritis, increased flow of saliva, acute pain, bloody diarrhea, extreme prostration, convulsions, and coma occurring in rapid succession. A _ garlicky odor of breath and icterus complete the clinical picture. If the patient is taken into a darkened room, his breath, feces, and urine appear luminous. If the patient survives the acute symptoms, fatty degener- ation, chiefly of the liver, takes place, from which the animal may die later on. Treatment.—An emetic of two grains of copper sulphate in water should be given and repeated until the stomach is completely emptied. Copper sulphate is both an emetic and an antidote for phosphorus, forming an insoluble phosphid of cop- per. . Afterall -the poison: has’ been ejected by vomiting that it is possible to eject in this way, demulcents and opiates should be given, but on no account should oil or milk be used, as they hasten the absorption of the phosphorus. To coun- teract the extreme prostration and collapse asso- ciated with phosphorus poisoning, subcutaneous in- jections of strychnin sulphate (gr. 1-200 to gr. 1-60) or one-half to one ounce of spirits of camphor should be given. Strychnin Strychnin poisoning is probably the most com- mon form of poisoning with which the veterinarian has to deal. The dog poisoner generally chooses this powerful alkaloid to attain his nefarious ob- ject. In addition, canine patients are extremely susceptible to strychnin and poisoning frequently results from overdosage of this drug. These lat- ter cases, however, are usually quickly amenable to treatment, In malicious poisoning, on the other 176 CANINE MEDICINE AND SURGERY hand, the mortality is high on account of the mass- ive doses employed. The length of time which elapses before symp- toms of poisoning appear after the ingestion of toxic quantities of strychnin varies considerably, depending on the nature and amount of food in the stomach. Absorption is retarded by a full stomach and by food stuffs of a fatty nature. The author has records of a case in which this delayed ab- sorption is well illustrated. The patient on her return home was given a bowl of milk, after which she was under continual observation until the symp- toms of strychnin poisoning developed, a period of four hours. The dose in this instance must have been a large one, as the bitch was saved only by heroic doses of H-M-C, being nee narcotized for twenty-four hours. Symptoms.—Uneasiness, an anxious expression, and panting, followed by acute tetanic spasms at varying intervals, are indications of strychnin poisoning. The spasms affect the whole body, the limbs become stiffened, and the animal, unable to stand, falls to the ground. The jaws are in a state of trismus, the lips being drawn back, espe- cially at the commissures, producing the character- istic risus sardonicus. The spine is curved (lordosis), inspiration is labored, and the mucous membranes are cyanotic. The eyes are prominent, the pupils dilated, the heart action tumultuous, and the pulse small and quick, but the artery full and_ hard. After the spasm the muscles relax and the fore- going symptoms abate until another paroxysm sets in, and these become more and more frequent, with shorter intervals, until ultimately the patient dies from asphyxia during one of the convulsions. Treatment.—Immediately an emetic of 1-10 to 1-20 grain of apomorphin hydrochlorid should be — POISONING 177 administered hypodermically to produce prompt vomi- tion of the unabsorbed portion of the poison. No mat- ter what treatment is resorted to for the purpose of allaying the spasms, this emetic must be given first of all; unless the quantity of strychnin ingested be very small, all other treatment is futile, and a fatal termi- nation certain if this is neglected. If the patient can swallow, the emetic may be followed by a liberal dose of oil. To control the spasms, the animal must be chloroformed, or an intravenous injection of chloral hydrate may be given. Large doses of morphin sulphate may also be used subcutaneously; but the treatment that has given the best results, and has in addition the ad- vantage of easy administration, is the hypodermic injection, after the production of emesis, of from three to five tablets of H-M-C (No. 1). The main object is to keep the patient free from spasms until the poison is eliminated. These injections of the H-M-C tablets should be repeated in sufficient dose to attain the result, the procedure being entirely without danger. The patient when completely nar- cotized should be placed in a dark and quiet place and all noise and excitement avoided,- or a return of the paroxysms will result. Hydrocyanic Acid and Potassium Cyanid These poisons are sometimes used by the dog poisoner, the latter being the more used of the two. Symptoms.—The rapidity with which this poison usually acts does not allow of the development of definite symptoms, but when relatively small toxic doses have been given (luckily the commercial potas- ‘sium cyanid is often impure) the following symptoms appear in a few minutes after the ingestion of the poison: Great distress, difficulty in breathing, head and neck extended, and convulsive movements of 178 CANINE MEDICINE AND SURGERY the fore limbs. The patient next falls on his side and goes into convulsions, the spine being alter- nately arched (kyphosis) and curved (lordosis). There is champing of the jaws, an increased flow of saliva, spasms of the diaphragm, asphyxia, and death. Treatment.—Death usually takes place so quickly as to preclude treatment, but if there is time, 1-10 to 1-20 grain of apomorphin hydrochlorid should be given for its emetic effect, and the poison neutral- ized with a solution in water of ten grains of iron sulphate. Complete anesthesia should then be: in- duced by the administration of ether. Carbolic Acid (Phenol) Dogs are extremely susceptible to the effects of carbolic acid and are often poisoned by being washed in a strong solution for the eradication of vermin, or by licking wounds to which carbolic dressings have been applied. Symptoms.—When taken by the mouth the caustic action of carbolic acid is observed by the stomatitis, pharyngitis, and gastroenteritis which it produces. The mucous membranes that have been touched by _it appear white in patches. When phenol is absorbed into the general circulation the following symptoms appear: The patient is anxious and distressed; there are fits of rigors and convulsions followed by paralysis of the hind quarters; the pulse is small, irregular, and barely perceptible; the respiration is quick and difficult; the temperature subnormal, and the urine high colored. Treatment.—Alcohol neutralizes carbolic acid and is, in addition, a stimulant. It should be given in full doses, one to two ounces, or if it be obtainable give gin, one to four ounces. A full dose of sodium sul- phate should then be given for a purgative. This POISONING 179 also in a measure neutralizes the poison. The in- flamed mucous membranes should be soothed by the administration of oil or demulcents. The failing res- piration should be combatted by repeated full doses of atropin sulphate (1-100 to 1-25) administered hypodermically. . Iodoform Poisoning from this agent is usually due to absorp- tion from wound dressings or from the patient lick- ing wounds that have been dressed with iodoform. Symptoms.—Gastric disturbances, vomiting, con- stipation, and convulsions alternating with coma, are produced by the ingestion or absorption of toxic quantities of iodoform. In some cases there is great excitement and difficult breathing. The pulse is irregular. Treatment.—Eliminate by emetics and give starch to form insoluble starch iodid. The foregoing list of poisons comprises those usu- ally met with in practice; for a more extended list, the reader is referred to special works on toxicology. PARE eT SURGICAL OPERATIONS Sy Lal OU ak PRELIMINARIES HE successful carrying out of an operative pro- cedure depends partly on the skill of the oper- ator and still more on the rigid adherence to the rules of asepsis and antisepsis. To attain these es- sentials, some means of restraining the patient’s movements must be provided for. There are numer- ous and varied types of operating tables to be found on the market, but for all practical purposes a per- fectly efficient table may be devised at home. An ordinary kitchen table, enameled white, makes a thoroughly practicable and cheap substitute for the high-priced tables sold by the surgical supply houses. The top of the table should be removed and fixed on again with hinges at one end, to allow the top to be tilted at any angle. At the other end of the framework of the table a square frame is hinged, the top of which butts against slats screwed on the inferior surface of the table top. In this way vari- ous angles of inclination may be obtained. On the table top are screwed four cleats, one at each corner, to which to affix the hopples. The hopples themselves may be made of tape, small- sized cotton rope, or webbing. A loop is made in one end of the hopples and a slipknot formed by passing the other end through the loop. In secur- ing the patient the slipknots are placed on each leg, above the carpus or the tarsus, as the case may be, the patient stretched out, and the ends of the hop- 180 ANESTHESIA 181 ples passed round the cleats in figure-of-eight style. The positions in which the patient is placed are the abdominal and the ventral. In the former the patient is stretched on the table on his belly; in the jatter, on his back. Occasionally the position of lateral recumbency is required, when the patient is placed on his side and the feet secured to the cleats opposite to each other. Anesthesia To obtain the best results, as well as for humani- tarian reasons, all operations (with the exception, perhaps, of evacuating an abscess, which as a rule requires only one bold stroke of the knife) should be performed under anesthesia. Anesthesia may be either local or general. As a general rule local anesthesia is applicable only in minor operations of short duration. It is applied by a spray to the part to be operated on, or the part is injected subcutaneously, by means of an ordinary hypodermic syringe, with the anesthetic selected. Ethyl chlorid is sprayed on the site of operation until the tissues are nearly frozen. It is of use only in such operations as opening an abscess or giving an intravenous injection, because the anesthesia is only fleeting and cannot be pushed on account of the danger of the tissues sloughing from too prolonged freezing. The anesthetics admin- istered hypodermically are solutions of cocain, eucain, urea and quinin hydrochlorid, alypin, acoin, novocain, and stovain. Of these cocain is probably the most used and is quite safe, provided that the amount injected does not exceed three-fourths of a grain. Although solutions of varied strength may be used with the above limitation as to dose, a four-per-cent solution is found to be the most suit- able for general work. It must be remembered that 182 CANINE MEDICINE AND SURGERY cocain has toxic properties and that no more than a tenth of a grain per pound weight of the patient should be injected at one time. The addition of adrenalin to the solution not only delays absorption into the circulation and so diminishes the risk of poisoning, but by constricting the capillaries it renders the operative field comparatively bloodless— a great advantage in some operative procedures. Technic.—The site of operation is shaved and cleaned up as described hereafter, and a sterilized hypodermic syringe is filled with the anesthetic solution. A sterilized needle is introduced under the skin in the usual manner, the syringe attached, Chloroform Inhaler. a few drops injected, and the needle withdrawn. Within the wheal produced by the first injection the needle is again introduced and another injection made, and so on until the whole operative area 1s injected. Gentle massage to the part is then applied for a minute or so in order to distribute the solu- tion. A pause of about fifteen minutes must be made before commencing the operation. General Anesthesia Being so easily and safely induced, general anes- thesia in canine practice is by far the most prac- ticable and satisfactory. The general anesthetics most in vogue are chloroform and ether, but various mixtures of these, with or without the addition of alcohol, are often substituted, but with no advan- ANESTHESIA ‘88 tage to the patient. The safest and most desirable method of inducing general anesthesia is as follows: About one hour previous to the operation the pa- tient should receive a hypodermic injection of H-M-C (hyosein, 1-100; morphin, 1-4; catin, 1-64), this usually produces vomiting in ten minutes. The dose must be gauged by the animal’s age and gen- eral condition, and varies from one No. 1 tablet for a puppy or small dog to five No. 1 tablets for a collie or bull terrier. The anesthetic is then com- pleted by a few whiffs of chloroform administered by means of a Funker’s inhaler or some _ similar apparatus. The advantages gained by using this method are (1) the emptying of the stomach; (2) the small amount of chloroform required to produce profound but safe anesthesia; (3) the long post- operative hypnosis that the patient enjoys, with corre- sponding benefit to the healing process. Chloroform alone may be quite safely administered -if due considerations are given to the following de- tails: 1. The patient must be prepared by fasting and the exhibition of a laxative twelve hours previous to operation, 2. The anesthetic must be administered slowly and be largely diluted with air. 3. The anesthetic must be administered only in sufficient quantity to inhibit the reflexes. 4. A sharp lookout must be kept for the danger signal, namely, shallow respirations. It. must be remembered that it is the respiratory center that first becomes paralyzed, and that respiratory failure . precedes cardiac failure. 5. At the first sign of respiratory trouble the anesthetic must be immediately discontinued, stimu- lants given, and if need be artificial respiration per- 184 CANINE MEDICINE AND SURGERY severed with until normal breathing is again estab- lished. 6. In case of sudden collapse, every effort must be made to reéstablish respiration. Remove the chloroform mask at once, pull the tongue forward with the tongue forceps, and drop on the back of the tongue the requisite dose of Scheele’s acid.* The dose of the acid is one-eighth of a minim for each pound in weight of the animal. The sudden gasping which immediately takes place-on the administering of hydrocyanic acid in a large majority of cases starts the respirations again. Then give the patient a smell of strong ammonia and a hypodermic of 1-100 to 1-50 grain of strychnin, according to its size. If these measures fail, give adrenalin solution (1-1000) hypodermically. In addition to this medicinal treat- ment, artificial respiration must be resorted to. Technic.—The following apparatus, instruments, and drugs are required to be ready to hand: Chloro- form apparatus as illustrated, chloroform, strong ammonia, Scheele’s acid (one eighth minim to a pound weight of patient), medicine dropper, hypo- dermic syringe filled with strychnin solution (1-50 grain), adrenalin solution (1-1000), and tongue forceps. Administration.—The patient should be secured in the abdominal position on the table and the mask applied over the nose and mouth. |The anesthetist then gently squeezes the bulb of the apparatus, taking care to give the patient plenty of time, after the first struggles have subsided, and the patient passes into the second or narcotic stage, recognized by a series of short, sharp yelps or whining. Then the chloroform may be pushed faster until the anes- *A five-per-cent aqueous solution of absolute hydrocyanie acid; named for Carl Wilhelm Scheele (1742-1786), a Swedish chemist, ~ discoverer of chlorin and oxygen. STERILIZATION OF INSTRUMENTS 185 thetic stage is reached, as shown by the abolition of reflex action. The administration of the anesthetic must then be continued with great caution, the bulb being squeezed only often enough to maintain anestiesia. If due regard is given to this method of anes- thetizing, the patient is kept well within the safety zone and accidents will be of rare occurrence. The author has anesthetized hundreds of cases by this method, which is followed by Professor Hobday, without a single fatality. Preparatory Treatment of the Operative Area This most important preliminary must in all cases be rigidly carried out, as only by surgical cleanliness can healing by primary union be brought about. Technic.—All hair should be removed by clippers or scissors, the part thoroughly scrubbed with anti- septic soap and boiled water, and then shaved. The site of operation should then be rinsed with boiled water, or rubbed with swabs dipped in ether or gasolin, to remove the greasy secretion of the skin. This must be persisted in until the swabs come away perfectly clean. Tincture of iodin is then applied and allowed to dry, the process being repeated three times. The body of the patient should be covered with gauze wrung out in boiled water, to prevent hairs or dust getting into the wound during the operation. Preparation of Instruments One of the most important factors in the success- ful healing of surgical wounds is the prevention of pathogenic organisms being introduced either by instruments, sutures, dressings, or the operator’s hands. In other words, everything that comes in contact with a wound must first of all be rendered aseptic. Instruments can readily be sterilized by 186 CANINE MEDICINE AND SURGERY boiling for fifteen minutes.