- €alcutta: (LA & PHARMACOGRAPHIA INDICA HISTORY “G &% OF THE PRINCIPAL DRU OF V#HGETABLE UORIGIR, BRITISH INDIA BY. WILLIAM DYMOCK, BRIGADE-SU RGEON, RETIRED, LATE PRINCIPAL MEDICAL STGREKEEPER TO GOVEKNMENT, C. J. H. WARDEN, DAVID HOOPE: 2, Ghar SURGEON-MAJOR, BENGAL ARMY, QUINOLOGIST TO THE GOV14RN- ee PROFESSOR OF CHEMISTRY IN AND ay THE OALCUTTA MEDICAL COLLEGE, MENT OF MADRAS, OCOTACAMUND, aeaaekt (VC | Zonton:—KUGAN, PAUL, TRENCH, TRUBNER & Go “Lo, | Bombay :—EDUCATION SOCIETY'S PRESS, BYCULLA. —THACKER, SPINK & Co. 1892, OPINIONS OF THE PRESS. PHARMACOGRAPHIA INDICA... By W. Dymocr, C. J. H. WarpDEN, AND Davip Hooper. Parr IV.* Tux undertaking of the authors, in the preface of the first volume, to supplement the previous work published by Dr. Dymock with original investigation concerning the chemical composition and physiological action of Indian drugs, and to give toxicological statistics relating to the more important drugs, has been most conscientiously carried out. Consequently the present part, which completes the second volume, does not extend further than Nicotiana Tabacum, and the two volumes already published contain, as nearly as possible, twice as much matter as can be found in the ‘ Materia Medica of Western India,’ up to the same point, Yet there still remains enough matter to be treated of to fill at least one more volume. Several new alkaloids have been discovered during the chemical examination to which some of the hitherto unexamined articles of materia medica have been subjected. Of these some have received a name, but of others only sufficient has been obtained to indicate their presence, Of those which have received a name may be mentioned—Bahmanine from red behen root; Nyctanthine from Nyctanthes arbor tristis; Jasminine from Jasminum grandifiorum ; Salvadorine from Salvadora persica; Tylophorine from Tylophora asthmatica ; Demine from Demia extensa; and Cuscutine from a species of Cuscuta. A neéw glucoside, to which the name of Dregein has been given, has been discovered in Dregea volubilis, an asclepia- daceous plant, and another, viz., gymnemic acid, in Gymiema ileite>, a plant belonging to the same natural order. Toxicological statistics form a marked feature in the present volume, the recorded cases of poisoning by Plumbago rosea, Nertum odorum, nux vomica and stramonium are given in a tabulated form. The last two appear to be the poisons most commonly in use for criminal purposes in India, for the tables extend over twenty-seven pages in the case of nux vomica and thirty-two in that of stramonium. In some instances interesting information is contri- © Saliten « Kegan Paul, Trench, Triibner and Co. 1891. Demy pp. 305-644, i buted concerning plants that are common in this country, but of . which the medicinal properties are almost unknown here. . Thus Anagallis arvensis is said to be used in India as a fish poison and to kill leeches, and Orfila’s statement to the effect that three drachms of an extract of the plant proved fatal to a dog, and M. Gronier’s that the plant has a poisonous effect on hares is probably known to but few. Sonchus oleraceus, a common weed in this country, is mentioned as possessing active hydrogogue properties and being likely to be useful in ascites and hydrothorax, Pharatedographick Indica’ thus forms a work, the usefulness of which is by no means confined to India. Being brought quite up to date, it will be found very valuable for purposes of reference on materia medica generally. Here and there throughout the volume interesting historical notes appear. In one of these, nepenthe is identified with henbane, Baron Hammer Purgstall’s observation to this effect being quoted. “ Bendj,” the plural of which in Coptie is ‘“*nibendj,” re without doubt the same plant as nepenthe, which has so much perplexed the commentators of Homer, Helen evidently brought the nepenthe from Egypt, and bendj is there still reputed to possess all the wonderful qualities which Homer attributes to it. ‘ Pharmacographia Indica,’ like its namesake, isa work of reference that no student of materia medica can afford to be without, and which is not only valuable for the accuracy of its statements, but so far as its historical matter concerns cannot fail to prove most interesting to the student of Eastern languages, almost as much so as to the student of materia medica. The articles on poisons also _ _ should prove of great value to medical. jurists, more particularly in ‘India. Even the indefatigable searcher for new remedies will pro- bably find scope for his energies in the long list of articles of medica as yet untried in this country. One of the most promisi. -§ of these seems to be Cosmostigmu racemosum, the root= bark of which, in doses of five grains, has been found by the authors to be “ a most efficient. cholagogue, without purgative effect, but restoring the natural colour of the stools after the usual reme- dies, “mineral, Or dee red ete., had bases aban- doned in despair. iii ©. J. H. Warden, David Hooper, authors. Part ay pages 305— 642, with Index to second volume. In noticing preceding numbers of this monk which have come. to hand we have remarked that these authors are doing work for the materia medica of India, which for completeness, value and interest entitled it to compare with the work done by Fliickiger and Han- bury in their famous Pharmacographia. In the present number we have in the pages before us an account of about 100 drugs, which represent the following orders: Com- posite, Campanulaces, Ericacese, Plumbaginex, Primulacee, Myr- sinew, Sapotacee, Ebenacew, Styracee, Oleacew, Salvadoracee, Apocynaces, Asclepiadew, Loganiacew, Gentianacee, Boraginer, Convolvulaceee, Solanacee. The excellence of the contributions will receive the acknowledg- ment of all botanists, and the reliability of the material is assured from the names of the authors, hence the work may be regarded as having all the information at present known of the respective drugs — mentioned. The contributions to science by these gentlemen entitle them to warm praise. (Pharm, Record. July 30th, 1891.) Pharmacographia Indica,—A History of the principal Drugs of Vegetable Origin met with in India, By Wm. Dymock, Brigade- Surgeon, retired, ete,; C. J. H. Warden, Surgeon-Major, Bengal Army, ete.; and D. Hooper, als etc. _ tou don: Kegan Paul, Trench, Triibner & Co. 1891 Part IV. of this work, now oe us, completes its second volume, and besides several orders of minor importance treats of the drugs procured from the orders of Sapotacem, Styracem, Apocynacee, Asclepiadew, Loganiacew, Gentianacew, Convolvulacex, and Solan- acewx, This part is characterized by all the excellencies upon which we have commented in connection with the preceding parts on their publication. Among the plants a number are noticed which are either indigenous or spontaneous in North America, like chicory, taraxacum, Sonchus oleraceus, Anagallis arvensis, dulcamara, Stin< monium, ete.; while others are cultivated either for ornament OF other purposes, like Tagetes erecta, calendula, jessamine, oleander, = Ipomea Bona-nox, capsicum, tobacco and others. Far more nasi ous are those plants which are either indigenous to India or have become naturalized there from other tropical countries, (Ame Tourn, of Pharmacy. Ca 1891,) foe iv Part VI is in the Press and will be ready at-Midsummer. pendix, together with a copious Index of more than 1 0 app double-column pages, is under preparation, and will be published as soon as the work is completed, ve PHARMACOGRAPHIA INDICA. SCROPHULARINE. VERBASCUM THAPSUS, Tann. Fig.—£ng. Bot. viit., t. 549; Woodv. Med. Bot., #. 125, Great Mullein (Zng.), Bouillon blanc, Moléne (F*.). Hab.—Temperate Himalaya. Westwards to Britain, The root, leaves, and flowers. Vernacular.—Philla, Ban-tambéké ( Hind.), History, Uses, &c.—The Hindi names for this plant are well chosen: Phiilla signifies “covered with flowers ” and Ban-tambaékt “wild tobacco.” As far as we know it is not mentioned by Sanskrit medical writers. The Arabians describe it under the names of Adin-ed-dubb, “ bear’s-car,”’ and Mahizah- raj, ‘‘fish poison’’; it is also called Sikrén-el-hut, ‘fishes’ hem~ lock,” and in modern Arabic, idat-el-baida, “ white felt plant, ” and Busir. Mahizahreh and Busir are Persian names for Mullein, which is deseribed very exactly by Haji Zein in the Ikhtiérét. Mahometan physicians consider it to be hot and dry i in the third degree, and ‘prescribe it in gout and rheumatism in com- bination with aperients. They identify it with the ¢dspos or Propis of the Greeks of which several kinds are described by Dioscorides as useful in diarrhwa and cough, and externally as an emollient; one kind, $Aoyis kuywris, was used for — The nareotic action of cn g SCROPHULARINES. be well known to the Arabs and Persians. According to Dr. Stewart, the roots are used in Northern India as 4 febrifuge. In Europe Mullein has ae had a reputation in the pul- monary diseases of cattle, on which account it bears the name ‘of Cow’s Lungwort. In Germany the plant is placed in grana- ries to drive away mice. The stalks covered with pitch were ~ formerly used as flambeaux, from this practice the plant derived its names of Cierge de Notre-Dame and Fleur de grand Chandeler in France,-and High Taper in England. The leaves and flowers are considered to be demulcent, diuretic, anodyne, and anti- spasmodic, and have long been in use in diarrhea and pulmonary affections. An infusion of the flowers is used in France as 4 diuretic, anda cataplasm of the leaves as an emollient. The — seeds are said to be narcotic, and to have been used in asthma 4 and infantile convulsions. In 1883 Dr. F. J. B. Quinlan (Brit. a : Med. Journ.) drew attention to the popular use of the leaves 4 : boiled in milk as a remedy for phthisical cough and diarrhea in 4 Treland, and stated that the plant was cultivated in gardens on rather an extensive scale. and curative powers similar to those possessed by cod liver oil. ~ Description.—The root-leaves are from 6 to 18 inches 10 a He claims for it weight-increasing q ; length, the cauline oblong, the upper ones being acuminate and q 1 sessile on the stem, more or less crenate, thickly covered with what bitter taste, and a disagreeable odour when fresh, which is : | lost on drying. | The flowers form a spike 6 to 10 inches in length, the corolla : ’ | only i is collected. It is from 4 to ?inch in diameter, bright — ~ yellow, 5-lobed, smooth - aboye, and - stellately tomentose _ beneath; attached to the tube are the stamens, of which the | _ thre 1 ae lower jonger, and se | it, whitish, stellate hairs. They have a mucilaginous some: s + ON es ol ll 4 | water acidified with hydrochloric acid. When agitated with __ petroleum ether the acid solution yielded some colour to it, Pada to be an easily , daca compo SOROPHULARINES. er. The seeds are about z', of an inch in length, cone-shaped, finely pitted, very tough and difficult to powder, nearly inodorous, and have a somewhat acrid taste. Chemical composition.—Morin (Journ. Chim. Med. w., p. 223) obtained from the flowers a yellow volatile oil, a fatty acid, free malic and phosphoric acids, malate and phosphate of lime, _ acetate of potash, uncrystallizable sugar, gum, chlorophyll, and a yellow resinous colouring matter. _ Adolph Latin submitted the leaves to proximate analysis and found the constituents to be 0°50 per cent. of a crystalline wax, a trace of volatile oil, 0°78 per cent. of resin soluble in ether, 1:00 per cent. of resin insoluble in ether, but soluble in absolute alcohol, a small quantity of tannin, a bitter principle, sugar, mucilage, &c.. The moisture in the air-dried sample amounted to 5°90 per cent., and the ash to 12°60 per cent. He concludes that the plant contains many of the usual constituents, and a bitter principle which may be prepared by exhausting the drug with alcohol, dissolving the alcoholic extract in water and agitating with ether or chloroform. Several trials failed to secure this substance in a crystalline condition. It was found | to be soluble in water, ether, alcohol, and chloroform, and to possess a decidedly bitter taste. It responded to none of the tests for a glucoside or alkaloid. (Am. Journ. Pharm Feb. 1890. E. Li. Janson (1890) found that petroleum ether aia stronger ether used successively, extracted from the flowers about 4 per cent. in each case. A decided change i in the colour of the ei was noticed after the extraction with ether, which removed the yellow colour, leaving the residue of a dark green. _ The yellow colouring matter was either a part of, or else it was retained by, the resin dissolved by ether, and it was not found possible to Separate it in the pure state. The drug after exhaustion with ether yielded 10°06 per cent, to absolute alcohol. A considerable portion of this alcoholic extract was soluble in’ 4 SCROPHULARINEZ. crystalline extractive was obtained by making the above acid — solution of the alcoholic extract alkaline and agitating with ether; while chloroform subsequently extracted a red-brown amorphous mass. ere 7 Both of these extractives reduced Fehling’s solution, and many changes in colour were noticed, indicating that these substances take some part in the colouring matter of the flowers. 4 The drug was also found to contain 2°49 per cent. of mucilage, 11-76 per cent. of carbohydrate corresponding to dextrin, 5°48 per cent, of glucose, 1:29 per cent. of saccharose, 16-76 per cent. of moisture, 4°11 per cent. of ash, and 82°75 per cent. of — cellulose and lignin. No reaction indicating tannin was obtained with iron salts, but an aqueous solution of the alcoholic — extract yielded a slight precipitate with gelatin. The seeds — yielded to petroleum ether 20°75 per cent. of a bright green fixed oil. The acrid principle was obtained.from the aleoholic extract soluble in water by agitating with petroleum ether. The mois- — ture was 10°86 per cent., and the ash 3-90 per cent. (Amer. 4 | Journ. Pharm., Dec. 1890.). on gi a Celsia coromandeliana, Vahl, Wight Ic., ¢. 1406, is 7 an annual plant having the characters of Verbascum, which is | ‘common in many parts of India -in the cold weather, usually — appearing in fields or in the beds of rivers, It has much the — same medicinal properties as Verbaseum Thapsus, and has been — brought to notice by Dr. B. M. Chatterjee asa sedative and — gent in diarrhea. (Phar. of Ind., p. 161.) The plant is — ‘tightly bitter and abounds in mucilage. The natives usually express the juice (ang-ras) and administer it in ounce-doses as @ — cooling medicine in fever, skin eruptions, dysentery, and such — _ diseases as they consider to be due to heat of blood. : __ The plant is herbaceous, pubescent, and viscid; lower leaves lyrate, floral cordate, stem clasping ; 5 Lor longer than the _ calyx; calyeine segments ovate, sli y toothed, or oblong- Si ace a eS PK ee ee ee ee ee See ee — SCROPHULARINEA:. dD SCHWEINFURTHIA SPHAROCARPA, . A. Braun. Fig.—Burm. F. Ind., t. 39, f. 2; Wight Ic., t. 1459. Hab.—Aind, Biluchistan, Afghanistan. The herb in fruit. Vernacular.—Sannipat (Ind. Bazars). History, Uses, &c.—In Hindu medical literature and in popular use, San-nipdta is a term which signifies a combined derangement of the three humors, Vata, Pitta, and Kafa (air, bile, and phlegm), which is supposed to produce Sannipdtazvara, or fever with typhoid symptoms, The remedy for this condition is said to be.a plant called Sannipéta-nud, “ driving away sanni- pat,” and Nepala-nimba, “‘Nepal Neem ”’ or ‘“ Nepal. bitter.” At the present time the drug sold in the shops is S. spherocarpa, but whether it is the original Nepal Neem is difficult to decide, as at present we do not even know whether this plant is found in Nepal. In typhoid conditions the drug is considered-to act asa tonic, to promote diuresis, subdue fever, and remove the derangement of the humors. We are not aware of any experi- ments having been made with it by European physicians in India, though its near relationship with the Antirrhinums, which contain glucosides similar to those of Digitalis, would, we should have thought, have excited eur sin in regard to its physiological action. Description.—The drug consists of the Bast in’ fruit, broken up into small pieces. The fruit is a globular dry papery mucronate capsule, firmly attached to the calyx; the upper part of the capsule to which the placenta is attached is double; the placenta, which is large and oblong, is supported upon a thick peduncle, and occupies the centre of the capsule; to it are attached numerous straight 5-angled wedge-shaped seeds, which are packed closely together and fill the remaining space. The calyx is 5-partite, the upper segment very large and extend- ing over the fruit like a hood. Leaves ovate, leathery, about 1 inch long with short blunt hairs; margin much lighter in col ae than the rest of the leaf; seed straight, wedge-shaped, if 6 SCROPHULARINE &. prominent longitudinal ridges ; testa tubercular, each tuberele ’ minutely granular. The portions of stem, which are numerous, : are woody and covered by a thin grey bark; the central pith is = very large. The drug has a slightly bitter somewhat tea-like 7 taste. Chemical composition.—The powdered drug. treated with ether ' yielded a dark olive-green extract, consisting of chlorophyll _ and uncrystallizable fatty matter. Subsequent percolation with alcohol removed a deep brown extract, from which cubical crystals of alkaline chlorides separated on evaporation. J An aqueous solution of this extract had a saltish taste and gave : distinct precipitates with alkaloidal tests. The alkaloid was removed by ether in an amorphous condition, and gave no well- | marked colour reactions with the strong mineral acids. By continuing the exhaustion of the powdered drug with water, a a deep reddish brown extract was obtained having a bitterish and nauseous taste, and containing saccharine and. other matters which readily fermented. In order to ascertain if the drug contained a substance similar to digitalin, a fresh decoction of the powder was filtered and precipitated by tannin, the preci-_ pitate washed, mixed with an excess of alkali, and shaken with ether. The result was the separation of an alkaloid similar to ~ that previously found. As more recent investigators prepare . digitalin by exhausting with alcohol after treatment of the drug” with water, this process was adopted with Schweinfurthia. _+he resinous matter collected had an acrid taste, but no princip! : could = be obtained possessing the properties of digitalin, digitonin or digitoxin, to which, according to Schmiedeberg, the _ Poisonous qualities of digitalis are due. Besides the alkaloid, call ioe a. ae ere which we consider to be the active principle, the drug yielded 18°6 per cent. of mineral matter, , Lindenbergia urticefolia, Lem, Hook. Ie. Pls = K8r5, EER Cagn Plant throughout [India upon walls and ih nea tenia the Concanin chronic bronchitis, and SCROPHULARINEZ. 7 Marathi name in the neighbourhood of Bombay is Dho/. Rox- burgh, under the name of Stemodia ruderalis, gives the following description of it :—‘‘ Root ramous, seems perennial. Stems many, ascending, ramous, herbaceous, woody, somewhat viscous, the whole plant about 12 or 18 inches high. Leaves opposite, petioled, ovate, deeply serrate, soft, a little hairy; about an inch long. Petioles shorter than the leaves, channelled. Stipules none. Flowers axillary, subsessile, solitary, opposite, small, yellow. Calyx 10-furrowed, 5-toothed, permanent. Corol personate ; tube the length of the calyx; both lips projecting, and shut; apex of the under lip broad, depending, 3-toothed, of the upper one very narrow, bifid; inside of both hairy, and beautifully marked with small purple dots. Jilaments and anthers as in the genus. Stigma slightly 2-lobed.” (Flora Indica, I11., 94.) LIMNOPHILA GRATIOLOIDES, Br. Fig.—Lheede, Hort. Mal. iv., t. 85, and xii., t. 36, Hab,.—Throughout India, in swamps. The plant. Vernacular.—Kuttra (Hind.), Karpur (Beng.), Ambuli (Mar.), Manga-néri (Ma/.). | History, Uses, &c.—This small aquatic plant, in Sans- krit Ambu-ja, “water born,” and Amra-gandhaka, having’ an odour of mangoes,’ is considered to be antiseptic by the Hindus, and its juice is rubbed over the body in pestilent fevers. Rheede notices its use for this purpose, and also internally in dysentery combined with ginger, cumin, and other aromatics. He also states that a linimentis made from the plant with cocoanut oil which is used in elephantiasis. Roxburgh, under the name of Co/umnea balsamea, describes the plant and notices its grateful odour and aromatic taste. The Bengal name signifies “camphor.” The odour of the fresh plant is remarkably refresh- ing and agreeable and calls to mind that of camphor and oil of lemons. ————— eh ee VP eeeee et, ih E q 3 L. gratissima, Rheede, Hort, Mal. 2., 6, has similar pr perties and bears the same vernacular names; it. is also 1 8 SCRKOPHULARINEA.- medicinally as a cooling medicine in fever, and given to women who are nursing when the milk is sour. Description.—In its most common form a simple or ~ branched plant 4—8 in. high, with whorled pinnatifid leaves 4—? in. long, which, in wetter places, appears to acquire a few i emersed, opposite, entire leaves at the top of the stem, and numerous capillaceo-multifid ones at its base. The stems are stout or slender. Very small specimens from Rohilkund S| (Kuttra, Edgeworth) have very wiry simple stems 3 in. high, : and capillary peduncles three times as long as the leaves; E others have stout stems and peduncles, the latter shorter than _ we’ leaves.” Calyx t=} in. long, rarely larger. Corolla } in., : blue. (FV. Br. Ind.) HERPESTIS MONNIERA, J¥. B. et K. Fig.—Bot. Mag., t. 2557; Roxb, Cor. Pi. ii., t. 178; Bheede, © Hort. Mal. x., t.14. Gratiole de Inde (Fr.). a Hab.—Throughout India, in marshy ground. The — herb. q Vernacular.— Sufed-chamni, Barambhi ( Hind.), Dhop-chamni, 4 Brihmi-sék (Beng.), Nir-brami, Bdmba (Mar.), Nir-brami — (Tam.), Sémbr&éni-aku, Sémbrni-chettu (Tel.). | _. History, Uses, &c.—Dutt states that this plant is the Brahmi of the native physicians of Calcutta, where it is 4 __ considered to be a nervine tonic useful in insanity, epilepsy, _ fever, &c. Itis certainly not the Brahmi of the Nighantas, but — would appear to be the plant called J ala-brahmi or “ Water — _ Brahmi” by Sanskrit writers. Owing to a similarity in the — _ ames it has frequently been confounded with Hydrocotyle ' asiatiea, which is the Brahmi or Brahmi-manduka of the . Ainslie says that in Southern India the Gratiola ' considered ‘diuretic and : per nd useful in that sort o -SCROPHULARINEZ. 9 stoppage of urine whichis accompanied with ebstinate costiveness. Roxburgh mentions the use of the juice mixed with petroleum as an external remedy in rheumatism. These accounts do not agree with the properties ascribed to Brahmi by Sanskrit writers. Rheede says of it: —“Ex frequenti hujus plant usu, vacearum ubera lacte turgent; sit ef decoctum ex illa in lacte vaccino et recenti butyre, centra delirium temporibus inunguendum ; Pipere, Calamo aromatico, Myrobalanis et aqua oryze trita et assumpta, vocem redditsonoram.” In Pondicherry itis considered to be aphrodisiac, and in Ceylon, under the name of Loonoo- eweela, it is prescribed in fevers, Description.—Stems several, annual, creeping, round, jointed, smooth, succulent; leaves opposite, sessile, obovate, wedge-shaped, or oblong, smooth, entire, ebtuse, fleshy, dotted with minute spets ; peduncles axillary, alternate, solitary, reund, smooth, shorter than the leaves, one-flowered ; flowers blue; bracts 2-awled, pressing on the calyx laterally; calyx 3-leaved, the exterior three leaflets large, oblong, the two interior small, linear, all are concave, smooth, pointed and permanent, corel campanu- late, border 4-partite, nearly equal; anthers 2-cleft atthe base, blue; stigma large, somewhat 2-lobed ; capsule ovate, 2-celled, 2-valved; seeds very numerous, (Roxb., Flora Ind., 1., p. 141.) Chemical composition.—For the analysis the whole plant was used, dried at a low temperature and exhausted with 80 per cent. alcohol. The aleohol freed extractive was then agitated with petroleum ether; ether from an acid solution, and again with ether from an alkaline solution, and finally with chlosotived from an alkaline solution. Operating i in this manner, a trace of oily matter was obtained, soluble in alcohol with acid reaction ; two resins, one easily soluble in ether, the other soluble with difficulty, but both soluble in alkaline solutions and reprecipitated by acids ; an organic acid, and a tannin affording a green coloration with ferric chloride. An alkaloidal principal was also isolated, soluble in ether and in chlorefeorm, and affording a cherry red colora- oe tion in the cold with Fréhde’s reagent. No a tet reacly o were no 12 vey 10 SCROPHULARINEA. PICRORHIZA KURROOA, Benth. Fig.—Royle Ii., t. 71. Hab.—Alpine Himalaya; from Cashmere to Sikkim. _ The root. Vernacular.—Katki, Kutki (Hind., Beng.), Katuku-rogani — (Tam.), Katuku-roni (Ze/.), Bal-kadu (Mar.), Kutaki (Guz.). History, Uses, &c.—This well-known drug is the | Kutaki of Sanskrit writers, who speak of it as Dhanvantari- grasta, “the plant eaten by Dhanvantari,” the physician of the gods, whe was produced at the churning of the Ocean, holding © ) a cup of amrita in his hands; he was the author of the Ayurveda. In the Nighantas it bears the following synonyms: Rohini, Katu-rohini, Vakragra, Matsya-pitta, Matsya-vinna, ~ Kanda-ruha, Krishna-bhedi, Dvijéngika, Asoka-rehini, Saku- ladani and Chakriénga. It is described as digestive, bitter, _ pungent, dry, aperient, light and cold; andis recommended 4s a remedy for worms, asthma, bile, phlegm, and fever. — Kutaki is a favorite remedy in bilious dyspepsia accompanied by fever, and is given daily in decoction, with liquorice, raisins, and Neem bark, half.a tola (90 grains) of each, water 32 tolas, . In dyspepsia and dysentery itis — combined with aromatics and is given in doses of ten to boiled down to one-fourth, twenty grains. which the secretions are scanty and the bowels costive, and is often prescribed for children suffering fr Marathi name Bélakadu, “ children’s bitter.” for black Hellebore, and its medicinal prope: European writers upon Indian describes the drug in Pree: It is considered to be specially indicated in those cases in om worms, whence the © and unmistakably describe the latter plant _ thes. This mistake has misled most _ ian drugs, but Ainslie, though he 4 his article upon black Hellebore _ ees SCROPHULARINEZ. 1] (Mat. Ind.,1., p. 164), has the following remarks :—“ I have given: the names Kadagoreganie end Kali-kootkie as the Tamool and Dukhanie appellations of the black Hellebore, as the root procured in the Indian bazars is commonly said to be so; but I have great doubts of it, and I here offer a caution respect- ing it, as it by no means. agrees in appearance with the black Hellebore of the European shops.” Royle (Z7/. i, p. 291) notices that the root of P. Kurrooa possesses much bitterness and is employed medicinally by the natives. Irvine (Mat. Med.,. p. 58) mentions the use of Kutki as a tonic, but owing to a general impression that the bazar drug was Hellebore root, European medical men appear to have generally avoided making experiments with it. Mr. Moodin Sheriff was the first modern writer to clearly demonstrate that the bazar drug has no dangerous properties, but is a valuable tonic and antiperiodic. He also identified it with the P. Kurrooa of Royle, an identification which we are now able to eonfirm through the kindness of Mr. J. F. Duthie who has supplied us with a specimen of the plant collected in Kumaon. As regards the medicinal properties of the drug, the accounts given by Sanskrit writers appear to be correct. Mr..M. Sheriff speaks favourably of it as a powerful bitter tonic and anti- periodic. Other medical men in India have expressed a similar opinion, and we can state from personal observation that it is used. successfully as an antiperiodic in native practice; its slight laxative action is rather beneficial than otherwise. The dose as a tonic is from 10 to 20 grains, as an antiperiodic from 40 to 50 grains; it is best administered in combination with aromatics. Description.—The drug consists of a. rhizome, generally about the size of a goose-quill, but often no larger than a crow- quill, the lower portion of which is covered by a shrivelled, greyish-brown, corky bark, and marked by prominent. scars, the remains of rootlets; towards the: upper end it becomes larger (} inch in diameter),.and is thickly. set with dark greyish- brown scales, and terminates in a scaly leaf-bud or stem. The rhizome is generally broken into short pieces, from 1 to.2 12 SCROPHULARINEZ.. 2 inches long; the fracture is short, the root very fragile and: a light, and black internally; it has no odour, and a very bitter — taste. | Microscopie structure.—The corky bark is made up of numer- ous rows of empty brick-shaped cells ; within this is a cellular — parenchyma of oblong brown cells, containing a little granular — matter; next a dark brown line composed of wood cells, form- 4 ing the boundary of the inner column of the root; within this several very large bundles of dotted vessels arranged so as to — form a broken ring, which surrounds a central cellular paren- — chyma. 2 Chemical composition—A proximate analysis of this drug showed the following percentage composition :— i ot nt =e ee eae 1:06 Bitter principle (Picrorhizin) ...... ooo 14°96 D>: pees 3-85 Organic acid ppt. by lead .......... oot Glucose 11°53 Cathartic acid, &e. (water extract)... 9°33 Substances dissolved by NaHO ...... 7°62 Arabin bodies from erude fibre ...... 14°56 . Fibre .... | 24:00 Moisture 5-73 Ash 3°82 __ The bitter principle is a glucoside Picrorhizin, freely soluble _ in water and alcohol, but. almost insoluble in pure ether. Itis _ acid in reaction, is not precipitated from solution by lead salts or tannin, but is absorbed by animal charcoal together with any colouring matter that is present. Itis best obtained by © exhausting the powdered drug with crude ether, and is left, _ after the evaporation of the ether, in brown resinoid drops — which form ramified crystals on standing. It is difficult to obtain the picrorhizin in a crystalline conditi a or after ion i : SCROPHULARINE Zi. 18 picrorhizin is decomposed by hydrolizing it with a boiling I per cent. solution of hydrochloric acid for three hours, and a decomposition product, which we have named Picrorhizetin, is formed together with glucose. In obtaining 0-7 gram of picrorhizetin *368 gram separated during the first hour, -219 gram in the second hour, 113 gram in the third hour, and none in the fourth. Weighed quantities of the picrorhizin, after drying at 100°C., afforded, on hydrolysis, 62°48 and 62:79 per cent. of bicrorhizetin: as the result of two experiments. The glucose obtained from the decomposition was inactive towards polarized light. An infusion or tincture of the root boiled with diluted acid gradually loses its bitterness, and a large increase in the sugar is detected by Fehling’s solution. Picrorhizetin is a red-brown, brittle, resinous, tasteless body soluble in aqueous alkalies. It is insoluble in water, and its solution in alcohol is precipitated by ether. By heating with strong sulphuric acid or when being burnt it evolves an odour of benzoin. The wax after bleaching, and purifying by reerystallization from hot alcohol, had a melting point of 51°C. The organic acid. separated by lead was red-coloured and gave a greenish colour with ferric salts. No tannic acid’ was present. Some — picrorhizetin was naturally formed in the drug, and existed in a much smaller proportion in the freshly dried rhizome. After removing the bitter principle by continued percolation with alcohol, the mare was dried and exhausted with water, the dark red-brown solution was evaporated to dryness, and *2 gram of the residue was found to act asa decided purge. The aqueous extract treated with four volumes of alcohol afforded precipitates containing 145 and 15:3 per cent. of mineral matter, and with six volumes a precipitate was obtain- ed with 10°8 per cent. of ash. We rely upon the physiological action of this extract in considering cece ies acid to bea constituent. Commerce.—Value, Rs. 9 per maund of 374 a Kumaon . = annually exports about five tons of this drug. - 14, SCROPHULARINEZ. Plants of minor importance belonging to this order, which have a certain amount of medicinal reputation, are :— Torenia asiatica, Linn., Rheede, Hort. Mal. iz., t. 53, the juice of which is given on the Malabar Coast for gonorrhea, Vandellia erecta, Benth., Rheede, Hort. Mal. iz., t. 51, called Vaka-pushpi, or “crane flower,” in Marathi, is also used — in a ghrita as a remedy for gonorrhea, and the juice is given t0 ~ children who pass green-coloured stools. V. pedunculata, — Benth. Griff. Ic. Pl. “As., t, 418, 7. 2, in Marathi Gadagvel, 18 _ considered to have similar properties. Veronica Beccabunga, Linn. Reichb. Ic. Fl. Germ, — t. 1701, is used in Northern India under the name of Tezak, ‘‘cress,” as a diuretic and antiscorbutic. It is the Bachbunge of the Germans, Cressonée of the French, and Brooklime of the English. V. Anagallis, Linn. Reichb. Ic. Fl. Germ. t. 1762, which has similar properties, takes its place in otha parts of India. Sopubia delphinifolia, G. Don, Roxb. Cor. Pi. él ¢. 90, is an elegant annual, common in wet fields in the rainy season. The juice is applied by field labourers to their feet to heal sores caused by exposure to wet; it is astringent and stains the skin yellow at first but afterwards black. ‘Fhe plant was formerly named Gerardia, after John Gerarde, our old i botanist, and author of the “Herbal,” published it Pedicularis pectinata, Waill., and several other species are used in Northern India under the name of Mishran on | account of their astringent and hemostatic properties. Sip pada lat er or BIGNONIACE. 15 BIGNONIACEZ. OROXYLUM INDICUM, Pent. Fig.— Wight Ic., t. 13387; Bureau Monogr. Bign., t. 9; Rheede, Hort. Mal. t., t. 48. Hab.—Throughout India, The root-bark. Vernacular.—Arlu, Phalphala, Sona (Hind.), Nasona, Sona (Beng.), Mulin, Talpalang, Miringa (Punj.), Tetu, Jagdala (Mar.), Tetu( Guz.), Vanga adanthay ( Tam.), Tigdu-mara, Sone- patta (Can.), Pamania, Dundillam (Zel.), Peiani (Mai.). History, Uses, &c.—This is a small tree, remarkable for its terminal spikes of large fleshy lurid flowers, which appear at the commencement of the rainy season, and are follow- ed by very large, retrofracted, transversely compressed, some- what curved pods, with the convexity upwards. ‘The seeds are numerous, membranaceous, surrounded with a large, delicate, membranaceous wing. ‘The leaves are supra-decompound, and from four to six feet long., The root-bark is of considerable importance in Hindu medicine, as it is an ingredient of the Dasamula (see Tribulus terrestris); it is considered to be astrin- gent, tonic, and useful in diarrhoea and dysentery. Saran- gadhara recommends the juice of Syonaka expressed from the roasted bark in combination with Mocharas (see Bombax mala- baricum) as a remedy in diarrhoea and dysentery. He also says that the root-bark boiled in Sesamum oil is a good application in otorrhea, In the Nighantas the tree bears many synonyms, ‘ amongst which may be mentioned Prathu-simbih, “ having broad _ pods,” Siika-nasa, “having a nose like a parrot’s beak,” in allusion to the flower buds, Aralu, and Bhalluka-priya, “dear to bears.” It is described as digestive, appetising, bitter, astringent, cold, pungent; a remedy for wind, phlegm, bile, and cough. The bark is much used by the agricultural classes as an application to the sore-backs of draught cattle. It is ground to _ apaste with water and an equal proportion of turmeric, and _ rubbed on the part. Rheede notices the use of the bark as an s which are a 16 BIGNONIACE A application to wounds, fractures, &c., and of the root in decoction in dropsy. =z found it to be most powerfully diaphoretic; the drug has slig anodyne properties; also a bath, prepared with the bark, have frequently employed in rheumatism. Twenty-eight cases of acute rheumatism were treated with this drug, and in all the ~ results have been most satisfactory. The dose of the powder is from 5 to 15 grains, thrice daily; of the infusion (1 oun¢ of bark to 10 ounces of boiling water) an ounce three times 4 — day. Combined with opium it forms a much more powerful — sudorific than the compound powder of ipecacuanha, The drug — does not. possess any febrifuge properties.” —Jndian Medica Gazette, February and March, 1875, . Description.—The bark of the root is brown externally yellow internally, thick,. breaking with a short fracture. ‘Tha of the stem is soft and spongy externally, and of a pale brow2 colour, furrowed longitudinally ; the internal surface is fibrou and greenish yellow. The minute’ structure does not eall fo remark, but upon placing a section of the fresh bark under __ microscope in a little water the whole field is seen to be fille ___-with-delicate needle-shaped crystals which have escaped fro _ the cut cells of the parenchyma; in entire cells the erystal: e of an inorganic nature, can be scen in situ. The b 80. BIGNONIACEZ. 17 vegetable wax, which was subsequently identified as such after re-solution in limited quantities of ether and separation there- from. The latter on evaporation gave a brownish-yellow residue small in quantity and crystalline. When further purified by extraction with ether and the ethereal residue by benzol it was golden yellow, unctuous to the touch, and pronouncedly aerid. Under the microscope it presented the appearance of long, wavy, branching crystals, which dissolved readily in aleohol, chloro- form ether, petroleum ether, and benzol, B. The mare was next percolated with cold ether. After distilling off the greater portion of the ether, and allowing the remainder to evaporate spontaneously, a yellow mass studded with minute interlacing crystals was obtained, which when air- dried weighed about 4 grams. This product was treated with boiling proof spirit and filtered while hot; on cooling small yellow crystals fell out of solution, When quite cold the crop of crystals was collected and subjected to the action of boiling petroleum ether until freed from every trace of fat. It was then cystallized from boiling proof spirit until it had a con- stant melting point, and was no longer contaminated with un- erystallizable matter. The resulting crystals were dried under the receiver of an air-pump, and when constant weighed 0:9 gram, They were of a lemon yellow colour, about } inch in length, and melted at 228:5°—229° C. Alcohol, ether, glacial acetic acid, and hot benzol dissolved them readily, but they were practically insoluble in water hot or cold. The following reactions in connection with this interesting body have been noted, of which the most striking is its behaviour with the caustic alkalies. A minute quantity brought into contact with one drop of a weak solution of sodium potassium or ammonium hydrates causes it to assume immediately a cherry-red colour, which quickly passes into brick-red and olive- green. Owing to the insolubility of the crystals in water a proof ‘Spirit solution was used in applying the following tests:— 1. A solution of silver nitrate in proof spirit produced a bluish-black colour immediately, and after the liquid had sto IIL.—3 . ; ee 18 BIGNONTACE. fora few minutes black particles of reduced silver were preci~ pitated. 2. A solution of neutral acetate of lead in proof spirit g gave a ahi bulky precipitate insoluble in boiling acetic acid. 8. Lime water imparted an orange colour, which quickly changed to olive-green, followed by a precipitate of the same colour. 4. An aqueous solution of sulphate of copper gave a golden yellow colour, quickly followed by a dirty brown precipitate, the supernatant liquid being distinctly greenish. 5. Solution of ferric chloride (acid) produced a brownish-red colour, which, in a few minutes, turned smoke-colour. 6. Solution of subacetate of wines gave a golden yellow precipi- tate. 7. An aqueous solution of ; mercuric chloride produced a white precipitate. 3 8. An aqueous solution of permanganate of potash, acidified with sulphuric acid, was instantly decolorized. ae 3 solution of the crystals in proof spirit did not. reduce Fehling. The authors say :-—“ We have attempted to Lvackrss this body, by subjecting a strong alcoholic solution to the prolonged action of 10 per cent. solution of paces acid at a boiling © temperature, but without success. v have also inquired into its nature and sentosimal com=— n, bi t the results so far obtained are not sufficiently con- rp rated in this paper. We hope to be able ; i gablisk “ehortly a eseipemnentary. note Pores with ae in Lenton of in Mea BIGNONTACEA. 19 examination, proved to be largely composed of the yellow crystalline body oroxylin. The cold proof spirit solution of the alcoholic residue was evaporated to dryness and the extract treated with water and filtered. ‘The filtrate was treated successively with neutral and basic acetate of lead, and the “precipitates after washing were suspended in water, decom- posed by a current of sulphuretted hydrogen and the resultant plumbic sulphide removed by filtration. Sulphuretted hydrogen was also passed through the iiltrate from the basic or plumbic acetate and the pr pol pitated lead sulphide removed by filtration. The three liquids thus obtained, which for convenience may be denominated i., ii., iii., were then evaporated down and the respective residues examined. (i.) It was dissolved in the smallest quantity possible of cold water and diluted with many timesits volume of alcohol. After setting aside for twenty-four hours a precipitate.fell, giving the general characters of parapectin. The supernatant liquid on evaporation left a scaly residue, astringent to the taste, and perfectly soluble in water. Its aqueous solution reduced Feh- ling and gave a copious bluish black precipitate with ferric chloride. Lime-water produced a bright golden-yellow colour, followed by a reddish-brown precipitate. From the tannins — proper it differed in that it was not precipitated by solution of gelatine. (ii.) This residue apparently consisted of pectin Salsriised with small portions of No. iii. (iii.) This was a dark uncrystallizable treacly-looking resi- due, which imparted to the palate a feeble sensation of sweet- ness. It was very soluble in water and reduced Febling’s solution abundantly. A strong aqueous solution was precise tated by absolute alcohol. D. The mare from the alcoholic extraction was finally perco- lated to exhaustion with cold water, The liquor was evaporat- ed down and the extract obtained taken up with hot’ water, A considerable amcuat of albuminous matter, which ‘rem: insoluble, was removed by filtration. The filtrate was 20 BIGNONIACEA. successively With neutral and subacetate of lead and the preci- — pitates decomposed in the same manner as described under @. ~ ‘The three liquids obtained, i., ii., iii., were evaporated down. (i.) This residue was the smallest of thethree. After stand- 4 ing for a considerable time some crystals were deposited, which on examination proved to be citric acid. | ii.) Nothing of a crystalline nature was found in this resi- ~ due. It appeared.to consist chiefly of extractive matter. 7 (iii.) This residue after treatment with alcohol had the same 3 characters and oma the same properties as C. i, It was not further examin The result of our examination of this bark may be summariz- ed by stating the different principles which we have found— (1) crystalline fat; (2) wax; (3) acrid principle ; (4) oroxylin (8) chlorophyll; (6) pectinous substances; (7) Fehling-reduc- ing principle; (8) astringent principle; (9) citric acid; (10) : extractive matter.—Pharm. Journ. pees 27, 1890. . : -STEREOSPERMUM SUAVEOLENS, De. Fig.— Wight Ic., t. 1342. _ Hab.—Throughout the moister parts of India. The root 3 bark and flowers. ee oe tn ay Hisdas Pédri-gida (Can. : Padri, Pandan (Guz.). : a ; ine Madana-kama-pu (South India). History, Uses, &c.—This tree is the Pétala or Pita of Sanskrit writers, the flowers of which are said by the poets to so intoxicate the bee that he is unable to distinguish + ‘flower from another. The tree is sacred to Durga, the wife 0 Siva. it bears among other - aebage thos BIGNONIACEZ. 21 is described as cooling, sweet, diuretic, and tonic, and is recom- mended in dyspepsia, dropsy, cough, and heat of blood. P. 8. Mootoosawmy says that in Tanjore the flowers are taken in the form of aconfection as an aphrodisiac. The flowers pounded with honey are said to stop troublesome hiccough, and the ashes of the bark are used in preparing alkaline ley and caustic pastes. The bark is in use throughout India from its being one of the ingredients in the Dasamula or “ten barks.” (See Tribulus terrestris.) Tn parts of India where this tree is not found, various substitutes are allowed to be used. In Malabar and in the Concan 8. chelonoides, DC., is used as PAdri. (See Kiheede, Hort. Mal, vi., t. 25; Ainslie, Mat. Ind. it., p. 272.) Description.—Trunk tolerably erect, though not straight. Bark ash-coloured, and somewhat scabrous. Leaves opposite, pinnate, with an odd one, from 12 to 24 inches long. Leaflets opposite, from two to four pairs, oval, with lon g bluntish, narrow points slightly serrate, having both sides downy while young, and when full grown not downy and feeling harsh ; the exterior pair and odd one about six inches long, by three or four broad; the inferior pair, or pairs, smaller. Petioles swelled at the base, — roundish, when old scabrous. Panicles terminal, composed of a few spreading branchlets; the first and second pairs thereof opposite; the superior dichotomous, with a solitary pedicelled flower in the forks; all are downy, and somewhat viscid. Flowers large, of a dark, dull crimson colour, exquisitely fra- grant. Calyx campanulate. Border 4-cleft ; upper divisions with two minute points, outside a little villous. Corol, throat ample, woolly, convex above, flat and plaited beneath. Border, the upper divisions shorter, erect ; the three inferior ones longer and projecting, with the margins ofall much curled, Filaments 4, fertile, and between them a small sterile one. Anthers twin. Germ oblong, elevated on a glandular receptacle. Stigma 2-lobed. (Rovburgh.) Sir W. Jones gives the following descrip- tion of the flowers: —Corolla externally light purple above, ae brownish purple below, hairy at its convexity ; internally dark yellow below, aimethystine above, exquisitely fragrant; prefe ee 22 BIGNONIACE Z. by bees to all other flowers, and compared by the poets to the — quiver of Kamadeva (the Indian Cupid) £3 Chemical composition.—An infusion of the dried flowers con a tained saccharine, mucilaginous and albuminous matters, but no ~ alkaloid could be detected in either the aqueous or alcoholic ~ extract. Ether removed a small quantity of a wax-like solid a from the powdered corollas. STEREOSPERMUM CHELONOIDES, D¢. q Fig.—Wight Ic. t. 1841; Bedd. Fh. Sylv., t. 72: Rheede, — | Hort. Mal. vi, 26. Favas da Cobre (Port.), Adderbonen (Dutch). : Hab.—Throughout the moister parts of India. The flowers, leaves, and root. — Vernacular.—Pader, PaAdri (Hind.), Dharmara (Beng.), Padal (Mar.), Padri (Zam., Mai.), Tagada (Zei.), Padrigida Can.). : . 4 History, Uses, &c.—In the Concan and Malabar, where S. suaveolens is not found, this tree is used as the Pétala of the Nighantas. Rheede says of it :— ' intolerabilem dispellit foliorum decoctum. Limonis hujusque commixti succi medentur manie. Corticis vero succus, cum 3 fructu Pere subactus, immodicum inhibet fluxum menstruum. 5 Radicis cutis cum Calamo aromatico, zinzibere contrita, folio- -Tumqué Padri succo admixta exhibetur morsis & putrefaciente _ colubro, Malabaribus Polenga dicto.” Ainslie (ii., 272) says:— This pleasant tasted root, as well as the fragrant flowers of the tree, the Vytians prescribe in infusion as a cooling drink in “Viscerum rigorem fevers.” : : The tender fruit and flowers of S. chelonoides are used as vegetables by the natives of Western India. oo Deseri iption.—Tronk strajoht. ats va hi _ Description. —Trunk straight, of a greatheight and thie pee thick, scabs hace ae 1g | the inferior | orizo BIGNONIACEZ. 23 more erect to the top ; leaves opposite, pinnate, with an“odd one; about twenty inches long; leaflets opposite, short petioled, gener- ally four pair, the inferior smallest, obliquely oval, pointed, sometimes slightly notched about the margins, when young downy, afterwards smooth, about 4 inches long by two broad ; petioles about 9 inches long, channelled, smooth ; stipules none ; panicles terminal, the larger ramifications decussate, the smaller or terminal 2-forked, with a sessile flower in the cleft; pedun- cles and pedicels round, covered with oblong grey scabrous specks; bracts small, caducous; flowers pretty large, yellow, very fragrant; calyx 5-notched ; nectary, a yellow fleshy ring surrounding the base of the germ; filaments, there is a fifth sterile one between the lower pair; anthers double; stigma 2-cleft; silique very long, slender, twisted; receptacle of the seeds spongy, white, with alternate notches on the sides for the seeds to lodge in. (Rozb., Fl. Ind., II1., 106.) STEREOSPERMUM XYLOCARPUM, Wigit. Fig. Wight Ic., t. 1335-6 ; Bedd. Fl, Sylv., t. 70. Hab.—Deccan Peninsula. The wood and tar. Vernacular,—Kharsing (Mar.), Ghansing (Can.). oe History, Uses, &c.—This tree is a native of the forests of Western India from Khandesh to Malabar. It wasintroduced by Dr. Andrew Berry into the Botanic Garden at Calcutta, and is minutely described by Roxburgh. - The natives by a rough process of the same nature as that 1 which tar is obtained from Pine wood, extract from the wood a thick fluid of the colour and Boscistence of Stockholm tar, which: they use asa remedy for scaly eruptions on the skin. Two globular earthen pots are used, the upper contains the wood in small pieces; it has a perforated bottom and is fitted with a cover, and is luted to the mouth of the lower pot. Cowdung cakes are then piled up round the two pots and set fire to. 2 q Dr. Gibson appears to have been the first to draw attention | _. the use of this substance by’ the natives. From— some _ 24 BIGNONIACE#. which we have made with it, we conclude that its prope 1 are similar to those of Pine tar. Description.—The wood is hard, but easily split ; when sawn across it presents a yellow resinous surface; section examined with the microscope show that the yellow colou due to a solid resinous deposit in the pitted vascular system The tar has exactly the odour, colour, and consistence. of Stockholm tar. Heterophragma Roxburghii, DC., Roxb. Cor. Pl #., ¢. 145, yields a similar product. Its vernacular names are Waras (Mar.), Baro-kala-goru (Tam.), Bondagu (Te/.). - Dolichandrone Rheedii, Scem., is the Nir-pongelion of Rheede (vi., 29), who states that the seeds with ginger and Pavetta root are administered in spasmodic affections, and that name and Bocks tee 2 as he Dutch, Dolichandrone falcata, Seem. Bedd. Fl. Sylvs i. 7], a native of Oudh, Rajputana, Central and South India, has the reputation of being used to procure abortion, and the bark i is, it is stated, used as a fish poison. Dr. Lyon, Chemical Analyser to the Government of Bombay, | found, however, no ill effects to follow the administration of # which are about a foot in length by 3 of an inch in © Weoue and somewhat curved, may be used as abortion sticks, CRESCENTIA CUJETE, Linn. Fig.—Jacq. Amb., t. 111; Plumb. Gen., t. 109. Calabash: — | tree (Eng.), Calebassier (F.), sake -Hab.—South Specie “Cullivated 3 in India, ‘The fra te Vernavul a ees ’ fete pet BIGNONIACEA, | 25 History, Uses, &c.—The Calabash - tree - introduced from South America is now pretty well known in India, and. latterly we have observed the fruit being offered for sale by the herbalists for use as a pectoral in the form of a poultice of the pulp applied to the chest. In the West Indies a syrup is made from the pulp, which is much used in dysentery and as a pectoral, The tree has. oblong cuneate, often obovate, entire, shining leaves, and flowers variegated with green, purple, red and yellow. The fruit is large, gourd-like and green ; it varies much in size, being from 2 inches to a foot in diameter. Dr. Peckolt, of Rio Janeiro, states that an alcoholic extract of the not quite ripe fruit in doses. of 0:10 gram. acts as. a mild aperient, and that 0°5 gram. proves strongly drastic, without griping or ill effects. As an application against erysipelas, the fresh pulp is boiled with water until it forms a black paste, to _ which vinegar is added and the whole boiled together and spread upon. linen. Corre and Lejanne state that in Western Africa the: leaves, along with those of Adansonia digitata, are boiled and eaten, and the seeds are eaten roasted. The pulp of the fruit macerated in water is. considered to be depurative, cooling, and febrifuge ; it is applied to the head in headache caused. by insolation and to burns: roasted in ashes it is mildly purgative and diuretic, according to P, Labat; in the Antilles, Chevalier has recom-— mended it in dropsies. ae ee Description.—Fruit ovoid or nearly round, with a hard, green, woody shell: very variable in size. It is filled witha _ white, slightly acid pulp, in which are contained the flattened, somewhat cordiform seeds. Chemical composition.—A chemical examination of the fresh _ fruit pulp yielded a new organic acid, crystallizing in plates, _ to.which the name ‘erescentic acid’ has been. given. It was _ obtained by exhausting with water an alcoholic extract -6f _ the pulp, treating. the aqueous solution with lead acetate, 4 suspending the lead precipitate in water. and decomposing ang 7 nee 5: a as ee a _ prolonged penance. The 26 PEDALINEZ:. removing the lead, then evaporating to a syrupy consistence and leaving it to crystallize in a cool place. Besides crescentic acid, there were found tartaric, citric and tannic acids, two resins, a bitter and an aromatic extractive substance, and a colouring matter that appeared to resemble indigo. (Peckolt, Pharm Rundschau, Aug. 1884; Year Book of Pharm., 1885, p. 168.) PEDALINE. _SESAMUM INDICUM, DC. Fig.— Wight Ili., t. 163; Bot. Mag., t. 1688; Benti. ant Trim., t, 198. Sesame (Eng.), Sésame de l’Inde (Fr.). Hab.—Throughout the warmer parts of India, cultivated. The leaves, seeds, and oil. Vernacular.—Til (Hind., Beng.), Ellu (Tam.), Nuavvula (Tei.), Ellu, Kérellu (Mai), Yellu (Can.), Mothetil (Mar.), Tal (Guz.). History, Uses, &c.—In Hindu mythology Sesamum | seed is symbolic of immortality. According to the “Brahma — purana,” Tila was created by Yama, the “king of death,” after Grihyasutra of Asvaléyana directs 7 in honour of the dead, SesamuD PEDALINEA. 27 Hindus hope to obtain delivery from sin, poverty, and other evils, and secure a place in Indra’s heaven. These acts are, tilodvarti, “ bathing in water containing the seeds” ; édasnay?, ‘anointing the body with the pounded seeds ”; ¢idahomi, ‘making a burnt offering of the seeds”’ ; tilaprada, “ offering the seeds to the dead”’; tilabhuy, “eating the seeds”; and tilavapi, ‘throwing out the seeds.” Water and Sesamum seeds are offered to the Manes of the deceased. In the first act of Sakuntala this prac- tice (called Ti/-anjii) is alluded to by the anchorite’s daughter in love with King Dushyanta, when she tells her companions that if they do not give their assistance, they will soon have to offer her water and Sesamum seeds. (De Gubernatis.) In proverbial language a grain of Sesamum signifies the least quan- tity of anything—Ti/ chor so bajjar chor, ‘‘who steals a grain will —_ a sack”; Til til ka hisab, “to exact the uttermost farthing.” A worthless person is compared to wild Sesamum (J artila, Sans.) which yields no oil—ZIn tilon men tel nahin, ‘there is no. good in him.” Dutt remarks :—‘ The word Taila, the Sanskrit for oil, is derived from Tila; it would therefore seem that Sesa- mum oil was one of the first, if not the first oil manufactured from oil-seeds by the ancient Hindus. The Bhavaprakasa describes three varieties of Til seeds, namely, black, white, and red. Of these the black is regarded as the best suited for medicinal use ; it yields also the largest quantity of oil. White Tilis of intermediate quality. Til of red or other colours is said to be inferior and unfit for medicinal use. Sesamum seeds are _ used as an article of diet, being made into confectionery with _ Sugar or ground into meal. Sesamum oil forms the basis of most _ of the fragrant or scented oils used by the natives for inunction before bathing, and of the medicated oils prepared with various vegetable drugs. It is preferred for these purposes from the circumstance of its being little liable to turn rancid or thick, and from its possessing no strong taste or odour of its own. Sesa- mum seeds are considered emollient, nourishing, tonic, diuretic, and lactagogue. They are said to be especially ——- by regulating the bowels and removing cons eee te eer et 4 : : 28 PEDALINEZ. poultice made of the seeds is applied to ulcers. Both the seeds and the oil are used as demulcents in dysentery and wnnniet? diseases in combination with other medicines of their class.” (Mat. Med. of the Hindus, p. 216.) Mahometan writers describe the seed under the Arabic name of Simsim. In Africa it is called J uljuldn,* and in Persia Kun- jad. The Mahometan bakers always sprinkle the seeds upon their bread, the sweetmeat-makers mix them with their sweets. The following Delhi street-ery indicates the properties attribut- ed to them by the latter class of people : — : é “Til, tikhur, tisi, dana, Ghi, shakkar men sana Khaé buddha, hoe javana,.”” * Sesamum, tikhur, and linseed, Butter and sugar, Poppy seed, Old men it makes quite young with speed.” (Fallon.) » Phe oil, which is called in Arabic Duhn-el-hal, is used for the Same purpose as olive oil is in Europe. Sesamum is considered fattening, emollient, and laxative. In decoction it is said to be emmenagogue; the same preparation sweetened with sugal is preseribed: in cough; a compound decoction with linseed is used as an aphrodisiac; a plaster made of the ground seeds is applied to burns, scalds, &c.; a lotion made from the leaves is used as a hair-wash, and is supposed to promote the growth Of the hair and make it black; a decoction of the root is said to have the same properties; a powder made from the _ Yoasted and decorticated seed is called Réhishi in Arabic and == That which is Ugla (a thing) great in estimation. (ibm — _ Abbad in T4j-el- ) — ~ _ nd)—The fruit of Coriander. (Sigh, Mughrib, Kémis.) _ Ora) Sesame. (Sibih, “Ez-Zamakhsher}, Mughrib, T4j-el- Aris-) . Gece before itis reaped. (Sihéh.) The grain of Sesame: *y ’s core. PEDALINEA,. 29 Arwah-i-Kunjad in Persian ; it is used as an emollient, both externally and internally, Sesamum (ovjrapov) 18 frequently mentioned by Greek and Latin authors. Lucian (Pise. 41) speaks of a onoapaios ee this was probably similar to the t:7 ka laddu of India. Sesame oil was an export from Sind to Europe, by way of the Red Sea, in the days of Pliny. In the Middle Ages the plant was known as Suseman or Sempsen, a corruption of the Arabic Simsin or Samsim, It is now called by Europeans, both in India and Europe, Jinjili, Jugeoline, Gigeri, Gengeli, or Gingelly, which appear to be corruptions of the word Juljulén. The oil is one of the most valuable of Indian vegetable oils; it keeps for a long time without becoming rancid, and is produced in large quantities in almost every part of the Peninsula. The following mode of preparation is described in the Jury reports of the Madras Exhibition :—“The method sometimes adopted is that of throwing the fresh seeds, without any cleansing process, into the common mill, and expressing in the usual way. The oil thus becomes mixed with a large portion of the colouring matter of the epidermis of the seed, and is neither ‘so pleasant to the eye nor so agreeable to the taste as that obtained by first repeatedly washing the seeds in cold water, or by boiling them for a short time, until the whole of the reddish-brown colour- ing matter is removed and the sceds have become perfectly white. They are then dried in the sun, and the oil expressed - as usual. The process yields from 40 to 44 per cent. of a very pale straw-coloured ee oil, an excellent substitute for olive oil.” Hydraulic presses are now in use in the more civilized parts of India for extracting the oil, but have as yet by no means - superseded the native oil mill. Sesamum oil may be used for plaster-making, but it takes more oxide of lead than groundnut oil, and does not make so light-coloured or so hard a plaster. After a prolonged trial at the Government Medical Store Department in me its use : was abandoned in favour of the latter. oil for the 30 PEDALINE. reasons :—The rolls of Sesame oil plaster soften in hot weather. The plaster has a disagreeable odour. It darkens in colour when kept for any time. For liniments and ointments, except Ung. Hydr. Nitratis, it appears to be a perfectly satisfactory substitute for olive oil. F. H. Alcock (Pharm. Journ. [3], Xv-s 282) recommends its use in making Lin. Ammoniz B. P. Sesame or Benne leaves, preferably in the fresh state, are much used in America as a demulcent in disorders of the bowels; they yield an abundant mucilage, Description.—Annual, 2 to 3 feet; leaves opposite or upper ones alternate, ovate, oblong or lanceolate, the lower ones often 3-lobed, or 3-divided, feather-nerved ; at the base of the peduncles are remarkable yellow glands ; flowers solitary in the - axils, resembling those of the fox-glove, from dirty white to rose-coloured, capsule velvetty and pubescent, mucronate, at first 2-celled, afterwards 4-celled; seeds numerous, without wings, ovoid, flat, white, brown, or black, rather smaller than linseed. : "Chemical composition.—The following table shows the relative composition of the brown or Levantine, and yellowish or Indian, seeds :— Levantine. Indian. Oil 55°63 50°84 ; Organic matter...........; 30°95 35°25 Re Aah... Perey i 6-85 oo ee aS 3:90 7-06 the albuminoids fen equal to 21°42 and 22-30 per cent. respectively i in the two varieties. In the manufacture of the oil the seeds are generally pressed three times: twice cold. and the third time warm. In i. Calcutta, where the seeds are Oany. pressed twice, the average yield is— ee ‘Ast Pressing of fine Oiler phen der 88 = cent fig 6: PEDALINE, 31 The oil-cake has the following composition :— Water : sees O20 Fat 7°63 Non-nitrogenous matter,..... 40°90 Albumenoids containing 5:25 per cent. nitrogen ......... 32°82 AB As . 10°40 (Brannt.) For further information on Sesame oil we would refer the reader to Vol. II. of Allen’s Commercial Organic Analysis, and to Brannt’s work on Oils and Fats. The authors of the Pharmacographia say :— The oil is a mixture of olein, stearin, and other compounds of glycerin with acids of the fatty series. We prepared with it in the usual way a lead plaster, and treated the latter with ether in order to remove the oleate of lead. The solution was then decomposed by sulphuretted hydrogen _ evaporated and exposed to hyponitric vapours. By this process we obtained 72°6 per cent. of Elaidic acid. The specimen of Sesame oil prepared by ourselves, consequently, contained 76-0 per cent. of olein, inasmuch as it must be supposed to be present in the form of triolein. In commercial oils the amount of | olein is certainly not constant. ee “As to the solid part of the oil, we succeeded in removing fatty acids, freely melting after repeated crystallizations at 67° C., which may consist of stearic acid mixed with one or more of the allied homologous acids as palmitic and myristic. By precipitating with acetate of magnesium, as proposed by Heintz, we finally isolated acids melting at 52°5 to 53°, 62 to 63°, and 69-2° C., which correspond to myristic, palmitic, and stearic acids. “ Sesame oil contains an extremely small quantity of a sub- _ Stance, perhaps resinoid, which has not yet been isolated. It may be obtained in solution by repeatedly shaking five vol 32 PEDALINEZ. of the oil with one of glacial acetic acid. If a cold mixture of equal weights of sulphuric and nitric acids is added in like volume, the acetic solution acquires a greenish yellow hue. The same experiment being made with spirit of wine substi- tuted for acetic acid, the mixture assumes a blue colour, quickly changing to greenish yellow. The oil itself being gently shaken with sulphuric and nitric acids takes a fine green hue, as shown in 1852 by Behrens, who at the same time pointed out that no other oil exhibits this reaction. It takes place even with the bleached and perfectly colourless oil. Sesame oil added to other oils, if to a larger extent than 10 per cent., may be recognised by this test. The reaction ought to be observed with small quantities, say 1 gram. of the oil and 1 gram. of the acid mixture previously cooled.” _ J. F. Tocher recommends the use of hydrochloric acid with a little pyrogallol for detecting the presence of Sesame oil; 14 parts of the acid and 1 part of pyrogallol are to be placed with an equal proportion of the oil to be tested in a test tube, which is corked and well shaken. The tube is then to be allowed to stand for five minutes, when, the upper layer of oil having been removed by a pipette, the acid solution is boiled for five minutes. If Sesame oil is present, it will show a purple colour when viewed by transmitted light, and a blue colour by reflect- ed light ; the latter colour is best observed when the fluid 1s poured into a porcelain capsule. After a time a slight blue ‘precipitate is thrown down. Olive oil tested with this re-agent afforded a faint yellowish colour, almond, groundnut and rape ‘oils no colour, and cotton-seed oil a very pale red. An admix- ‘ture of 1 to 2-per cent. of Sesame oil with olive oil may thus be detected. eye 4: 9 alee ee eas PED ALINB. |. with hydrochloric acid, collected on a filter, thoroughly washed | to free it from acid, and dried over a water bath. It was then soluble in alcohol and crystallized on cooling from its alcoholic solution in Jong needles melting at 117—118° ©. The needles were soluble in benzene, oil of turpentine, bisulphide of carbon, chloroform, and glacial acetic acid, but insoluble in water, alka- line solutions, and hydrochloric acid. They were neutral to test paper, and gave no colour reaction with the hydrochloric acid and pyrogallol solution, showing that this reaction is due to another principle in the oil which has not yet been isolated. (Pharm. Journ., Jan. 24th, 1891.) Sesame oil xiii by ether has a sp. gr. of 0°919 at 23° C, Commerce.—Sesamum is commonly cultivated in India; there are two varieties, the black-seeded and the white-seeded; the former being generally known as fi/, and the latter as til. Til ripens rather later than ti, and is more commonly grown, mixed with high crops, such as Sorghum vulgare, while tili does best when mixed with cotton. Tvli oil is preferred of the two for human consumption. (Duthie and Fuller.) The quantity of seed shipped from British India in the year 1871-72 was 565,854 ewts., of which France took-no less than 495,414 ewts. In 1881-82, the exports from Bombay alone were 994,120 ewts., valued at Rs. 64,84,475. France continued to take about 4-6ths of the total exports. Besides this, 105,344 gals. of oil, value Rs, 1,12,122, were exported to Eastern ports. Tn 1884-85, the exports from the whole of India were 2,654 _ thousand ecwts., and in 1887-88, 187 thousand tons, but in 1888-89 the exports fell to 77 thousand tons. This fall was probably due to an unfavourable season. No statistics of the consumption of the oil in India are available. It must be enormous, as Sesame oil i is the food oil of all who can afford it. PEDALIUM MUREX, Lon Fig. —Burm. Fi. Ind; t: 45, f.-2.° @artn: Fruct. i, 2+ oes ee 2 Wight Ie., t. 1615; Rheede Hort. Mal. ®ay (3s pips Hab. —Deccan Peninsula, Ceylon, The leaves, ae mn TiL—5 zi 4 PHDALINEZ.. Vernacular.—Bara-gokhru (Hind., Beng.), Peru-nerunji (Tam.), Pedda-palleru (Ye/.), Kéttu-nerinnil (Mai.), Anne- - galu-gida (Can.), Kadva-gokhru (Guz.), Karonta, Ubha-gokhru, Malvi-gokhru ( Mar.). History, Uses, &c.—This plant does not appear to have been used medicinally by the ancient Hindus, nor do we know of any Sanskrit name for it. It is supposed by Dr. Moodin Sheriff to be the Farid-biti (herb F arid), the plant upon which Shaik Farid-ed-din Shakar Ganj,* a Mahometan ascetic and poet, sustained life while he acquired the everlasting treasure of knowledge (Ganj-i-la-yaz4l-i-madrif). The follow- ing quatrain is attributed to him :— Shabnist keh khin-i-dil-i-chamnak narikht. { Riizi neh keh 4brié-i-man pak narikht, || Yak sharbat-i-4b-i-khtish nakhdrdam hameh ’umr. | Kan niz 2’rah-i-dideh bar khak narikht. || By night I am consumed with grief, By day I am overwhelmed with shame, No drop of sweet water passes my lips, But it pours in tears from my eyes. _ 2. Murex is the Caca-mullu of Rheede, who states that the powdered leaves are given in two-drachm doses with milk and sugar in gonorrhoea and gonorrheal rheumatism. The fresh plant agitated in water or milk renders it gelatinous without terially altering its taste, colour or odour. This thickening disappears after some hours. A watery infusion of this kind sweetened with sugar is a favourite and excellent demulcent in acute gonorrhea. The dried fruit is the Bara-gokhru of “ great Gokhru” of the shops, and a decoction of it is used when the fresh plant is not obtainable. In the Concan 4 Paushtik, or “ strengthening medicine,” is made of the * Shakarganj or “ sugar store.” Poison in his mouth became sugar— Mo 95 SS ,) e839 323 ae 02395 yp 9f-5 1 Cry Br) a Padhigr cbse (Hind., Beng.), Pén-ova (Mar.). History, Uses, &C.—This plant, found in every Indian garden, is the Coleus aromaticus of Loureiro, who describes it 23 resolvent, tonic and cephalic, and useful in asthma and chronic LABIAT A), 91 cough; also in epileptic and convulsive affections. Roxburgh _ (Fi. Ind., iii., 22) remarks that the leaves and all parts of the plant are delightfully fragrant, they are frequently eaten with bread and butter, also bruised and put into country beer, cool tankards, &c., being an excellent substitute for Borage. Amongst _ the natives of India the juice is a domestic remedy in colic and _ and irritation caused by the sting of the centipede. The chopped leaves, made into pellets and dipped in a paste made of the " flour of the chickpea, are fried in butter and eaten. Food pre- _ pared in this manner is a favorite Indian dish and is called ust | (bhajen). Dr. Wight speaks of the plant as a powerful aromatic carminative, given in cases of coli¢ in children, in the treatment - of which the expresssd juice is prescribed mixed with sugar or * other suitable vehicle. In his.own practice he observed it. to _ produce so decidedly an intoxicating effect that the patient, a had to discontinue it, though otherwise benefiting under its use. _ The Rev, J. Long (Journ. Agri-Hort. Soc., Ind., 1858, x., p. 23) also notices its intoxicating properties. In the Dict. Econ. _ Prod. of India, ii., 504, itis stated on the authority of Dr. A. C. _ Mookerjec that the expressed juice of the leaves is considered an anodyne and astringent, and is applied round the orbit in eases of conjunctivitis. One of us has taken large doses of the fresh juice of the leaves without observing any intoxicating fiect, and Mr. J. G. Prebble, who has experimented with a _ succus prepared from the fresh herb, informs us that in large ect. The swecws, a sample of which he has kindly supplied, had the smell and taste of weak infusion of liquorice root. Description.—The leaves of C. aromatieus, which. are road, ovate-crenated, and very thick, are about 3 inches long, nd thickly studded with hairs, which on the upper-surface are rincipally jointed and tapering, but a few are simple and surmounted by a globular, transparent, brilliant gland like a most numerous, and give rise to a frosted appearance. | 4 dyspepsia, and the crushed leaves are applied to relieve the pain _ _ European lady, who had taken it on native advice for dyspepsia, nd repeated doses it did not’ produce the slightest intoxicating ~ inute dewdrop. On the under-surface the glandular hairs are _ Z é 92 LABIATZ. epidermis is provided with numerous simple stomata, The — venation is reticulate, and remarkably prominent on the under- surface of the leaf. A few oil globules are met with in the — parenchyma, but the aroma is chiefly situated in the glandular hairs. The taste of the leaf is at first pleasantly aromatic, after- wards very pungent; the odour is agreeable and refreshing. » ANISOCHILUS CARNOSUS, Wal. Pig.— Wight Ii., t. 176 6, f. 1; Linn. Amen. Acad, «., 59, t. 3; Rheede, Hort. Mal. z., t..90. Hab.—Western Himalaya, Central and Southern India. The leaves and essential oil, 4 Vernacular.—Pin-jira (Hind.), Képérli, P4n-jiren (Mar) Karpptra-valli (Zam.), Roga-chettu, Omamu-aku (Zel.), Cho- mara, Karkha (Mal.), Dodda-patri (Can.). History, Uses, &c.— Ainslie states that the fresh juice of the leaves mixed with sugar-candy is prescribed by the Tamil physicians in cynanche, who also prepare with it, in conjunction with the juices of other herbs and gingelly oil, a cooling lini-: 4 thent for the head. Dr. G. Bidie (Madras Quart. Med. Journ, 1862, Vol. V., p. 269) describes it as a mild stimulant expec Be torant. Its properties depend upon a volatile oil. In the Dict. Econ. Prod. of India it is stated on the authority of Surgeon-Major North that the juice of the leaves mixed with sugar and human milk is a popular domestic remedy for children’s coughs in Mysore. Description.—Stem erect, tetragonal; leaves petioled, — ovate-rounded, obtuse crenated, cor date at the base, or rounded, thick, fleshy, hoary and tomentose, or villous on both sides; spikes long peduncled, at length cylindric; floral leaves ovate- obtuse; upper lip of calyx acute, glabrous, membranaceous, ciliated on the margin ; lower lip truncate, quite entire ; corol bilabiate; upper lip bluntly 3 to 4-cleft, lower lip entire; flowers lilac. ¢ i Se eo I LABIATE. 93 LAVANDULA STC:CHAS, Linn. a Fig.— Barrel. Ic., t. 301. Arabian or French Lavender 3 (Zng.), Steechas Arabique (/’r.). 3 Hab.— Mediterranean Coasts to Asia Minor and Arabia. _ The flower spikes. | Vernacular.—Dharu (Hind.), Ustukhudus (nd. Buzars). History, Uses, &c.—Dioscorides states that this plant is called Steechas from its growing on the Stochades, a group " of islands on the South Coast of Gaul near Massilia, now called “Isles d’Hyéres. It is the Cxyolbs! or Cw sighs! of Ibn Sina. It is much used by Mahometan physicians, who consider it to be cephalic, resolvent, deobstruent and carminative, and prescribe it in chest affections ; they also think that it assists in expelling bilious and phlegmatic humors. (Cf. Dios. iii., 28 ; Paul. Zig. vi.; Plin. 26, 27.) : _ The author of the Makhzan-el-Adwiya devotes a whole folio _ page to a description of its properties, and especially enlarges _ upon its cephalic virtues; he concludes by saying, “In short _ Ustukhudus is the broom of the brain, it sweeps away all phlegmatic impurities, and removes obstructions, strengthening _ its powers, expelling vain crudities, and rarifying the intel- & lect.” ; In Western India the drug is best known, though incor- _ rectly, under the Portuguese name of Alfazema,* which is _ corrupted by the natives into Alphajan. In European medicine the flowers furnish the base of the sirop de stechas composé, d are sometimes distilled for the sake of their essential oil, which is known as “false oil of Spike,” the true oil of Spike being the produce of LZ. Spica. ZL. Stechas is known in Spain as “Romero Santo” (sacred rosemary). Its essential oil (also that of D, dentata) is there 4 obtained for household use by suspending the fresh flowering © q * Lavandula vera, L. Stechas, is called Rosmarinho by the Portuguese _ a in Europe. re o — 94, LABIAT A. ~ stalks, flowers downward, in closed bottles and exposing them for some time in the sun’s rays; a mixture of water and essential — oil collects at the bottom, which is used as a hemostatic and for cleansing wounds. (J, C. Saver.) Description.—The purple flowers occur in short-stalked spikes and are situated in the axils of downy, heart-shaped bracts. The upper bracts, which are abortive, form a purple tuft at the top of the spike. a reddish-yellow colour, recalls that of oil of rosemary. Chemical composition—The specific gravity of Spanish oil of I. Stechas is 0:942 at 15°C. It boils between 180° and 245°. (J. C. Sawer, Chem. and Druggist, 1891, No. 567.) Commerce.-—The drug is largely imported from Europe. Value, Rs. 8 per maund of 37} lbs. : JADEH. ‘The 8942 of the Arabian physicians is generally considered be the Fuliyun (gédvor) of the Grecks; by some supposed to be th Poley-Germander (Teucrium Polium, Linn.).; it is described deobstruent, diuretic, anthelmintic, and tonic. (Diosc. iii., 1195 Plin., 21, 60, 84.) Dumolin, however, maintains the ré\.ov af the the “Lavender Cotton” of our gardens. Jadch as gid! wee 53, “a kind of Spaeanoal. Persian writers: on Materia Medica give Gul-i-urba and Amberbed as its: synonyms. Dr. Jayakar, Civil Surgeon at Muscat, and a distinguished Arabic scholar, forwarded to one of us in 1885 a plant growing on the hills near that town which is called Jadeh, and also 2 specimen of the Jadeh of the Muscat shops which comes from Bandar Abbas. Both of Dr. Jayakar’s specimens are woody, labiate plants, with linear leaves and terminal crowded spikes of flowers, both are densely a with. é cotton-like down, more 8 LABIATAE. 95 very closely related ; they are used in febrile affections by the Arabs, one ounce being steeped in cold water all night, and the infusion strained and taken in the morning. In infantile fevers the body is fumigated with the drug. = The specimens were forwarded to Kew, but have not, as far as we know, been identified. The Bander Abbas Jadeh, as sold in _ the shops, consists of the flowers mixed with a few leaves and stems. The flowers are about 3, of an inch long, and only _ protrude a little from the cottony calyx; they are permanent q and firmly attached to the seeds, which are black, rugose, and ¢ somewhat kidney-shaped. The odour of the drug somewhat resembles that of wormseed, while that of the Arabian plant is more like lavender. POGOSTEMON PARVIFLORUS, Benth. Syn.—P. purpuricaulis, Dalz, in Hook, Kew Journ, ti., 336. : : Hab. —Sub-tropical Himalaya, Decean Peninsula. The root and leaves, Vernacular.—Pangala, Phangala (Mar.). History, Uses, &c,—This plant hardly differs from _ P. purpurascens, and is very closely related to P. plectranthoides, _ P. glaber, and the variety suavis of P. Patchouli, It does not _ appear to be mentioned by Sanskrit medical writers, but the _ root has a popular reputation as a styptic. In the Ratnagiri _ District of Western India, the root has long been’ in use mongst the natives as a secret remedy for the bite of the hitirsa snake, and in February 1871, Mr. H. B. Boswell, the lector, addressed the Civil Surgeon in the following terms :— ‘I have the honor to send you a specimen of a root which I have reason to believe to be a cure for the bite of the Phiarsa _ snake, and I shall feel very much obliged to you if you can in - _ any way ascertain its medicinal properties and its effect on any _ one so bitten, 3 “* Tt is said to stop all the after ill-effects of this ‘poisonous - e ite, which is more than Liquor Ammonie will, I . id 96 LABIAT A. often do. The patient is to eat as much of it, after it has been : washed, as would make in bulk the size of the first joint of one’s first finger. This he is to do three times a day for seven days, — Tt is also to be applied externally to the wound. I cannot, of 3 course, vouch for the truth of this, or the efficacy of the cure, but E one of my sepoys, who was bitten by a Phiirsa a week ago, has been doctored by the Patel (village headman) of this place, in this manner, and is now apparently well. The Patel after much persuasion has shown me the root and the plant, one [know ~ well, but the name of which I am not at liberty at present to mention. He also assures me that this is all he uses.” _ The plant was forwarded in April 1871 to the: Chemical Analyser to Government, who identified it as a species of Perilla, and expressed an opinion that it was highly improbable that a plant belonging to the Labiatze would prove to be 4 — specific for snake-poisoning, and suggested that some trustworthy evidence of its value should be obtained before he undertook an analysis. In June of the same year, Dr. C. Joynt, the Civil Surgeon, reported the following case: —“ A sepoy, aged 27, was admitted on the night of the 29th; Liquor Ammoniz was applied to the wound after incising; next morning there was hemorrhage ~ from the wound, and also free hemorrhage from the gums and tongue, the blood escaping had a bright arterial hue. A scruple of the root was ordered three times a day. The first dose decidedly relieved the vertigo which he complained of, and» - next day there was a marked diminution in the haemorrhage _ from gums and tongue, which entirely ceased on the fourth day. _ No other medicine was given.” Dr. Joynt remarked :—“The- employment of the root in this case appears to have been _ singularly beneficial, and to deserve further investigation.” Unfortunately, Dr. Joynt left Ratnagiri shortly afterwards and was unable to continue his investigations. In the Annual Report of the Ratnagiri Police Hospital for the year 1873-74, | the following remarks by Dr. E.H. R. Langley, the Civil _ Surgeon, occur :—‘Snake-bites furnished two ‘cases; these- injuries were caused by snakes called ‘Phiirsa’ by the natives — (Echis carinata of-ophiologists). A rapid cure was effected by LABIAT#. 97 _ the internal administration, together with local application of _ the root of a shrub, ‘the Pogostemon purpuricaulis,’ very common all over the Concan.” In 1874 Dr. Langley made the follow-— ing report to the Deputy Surgeon-General :—“Thirteen cases arising from the bites of poisonous snakes were treated in the Civil Hospital, Ratnagiri. The only remedy used was the _ pounded root of a plant called Pang/a, the ‘ Pogostemon purpuri- _ caulis of botanists’; the root of this plant is given internally as ell as applied as a paste locally ; all these cases did well, and ere discharged from two to four days after admission.” In 1884 Dr. H. McCalman, Civil Surgeon, Ratnagiri, for- _ warded a communication, ‘‘On the treatment of Phoorsa bite by _ Pangls, root with illustrative case,” to the Bombay Medical and _ Physical Society,from which we extract the following remarks:— _ “The Echis curinata, a viperine snake, is very commen in the _ Ratnagiri District. Fayrer describes it as fierce, active and _ aggressive, always on the defensive, and ready to attack. The _ bite is eventually highly dangerous, although the symptoms may _ be slow in developing. In fatal cases death usually occurs in _ from 4 to 6 days, and is preceded by giddiness, great lethargy _ and depression, hemorrhagic discharges, albuminuria, and occasionally lockjaw.” : . . = *Pangla root, chewed in a fresh state, has been used for some years by Drs. Joynt, Langley, Barker and myself in the treat- ment of Phoorsa bite, and with invariable success.” The following is Dr. McCalman’s illustrative case :—Rowjee alsawant, Hindoo, police constable, aged 45, was admitted hospital on the 14th June 1884, at 6 a.m. An hour Previously he was bitten on the dorsum of the foot by a Phoorsa snake, afterwards recognized and killed. He was im- mediately given Pangla to chew, and a poultice of the leaves applied locally. At 9 a.m. there was. much pain in the part, _ edematous swelling of the foot and ankle, extending half-way 4 up the leg, giddiness, a feeling of great depression, and hzmor- _ rhage (dark-coloured) from the gums, under surface of the _ ©xpectorated did not coagulate. This bleeding had begun — q IIL.—13 oS _ tongue and buccal mucous membrane generally. The blood 98 LABIATZ. 6 a.m., an hour after the man had been bitten. Pulse 72, tem- 4 perature 98° F., no dyspnea. Finding the hemorrhage un — checked by the remedy, some perfectly fresh root just dug up wa substituted for that first given. The effect was soon apparent. At 2 p.m., giddiness less, pulse 78, temperature 99" expression tranquil, urine dark-coloured, depositing @ sligh flocculent sediment, reaction acid, sp. gr. 1012, albumen to considerable extent. Pain of the foot less. 6 p.m., bleeding from the mouth practically stopped, giddiness — increased, pulse 72, temperature 99°4. Urine shows bl corpuscules under the microscope. 15th.—No hemorrhage from the mouth; urine contains considerable quantity of blood; vertigo less. Swelling of i less. Pulse as yesterday and of fair volume. 16th.—No hemorrhage whatever. No giddiness. Us pale, no sediment, no albumen, sp. gr. 1008. Pulse 66. Stiffness — of foot, but no real pain, 17th.—Swelling rapidly disappearing. No head symptom Urine very pale and plentiful, sp. gr. 1004. 18th.—Pangla omitted. His convalescence was uninterrupt ed, and he left the hospital on the 22nd perfectly well. Dr. McCalman remarks :—‘‘I do not pretend to explain th : action of Pangla; that the remedy acts generally and physiolo- : gically is apparent from the early drying up of remote hemers rhages (¢.g., bleeding from the urinary tract) and the relief _ cerebral symptoms, effects due to a restoration of the natural ‘state of the blood, and, through it, of the nervous centres. Th. drug may also stimulate organs concerned in the elimination © the poison. The subject is one which calls for further careful experimental research.” Through the courtesy of Surgeon-General Pinkerton we have been supplied with further extracts from the records of the Ratnagiri Civil Hospital, which show that Pangla root is still used with the same success in the treatment of Pharsa bite . LABIATA. 99 Only one fatal case is recorded, and in that the remedy was administered in the form of tincture instead of in the usual manner. | Mr. G. W. Vidal, C.S., in a letter to the Bombay Gazette, dated January 30th, 1890, states that the bite of the Phirsa snake is apparently fatal in about 20 per cent. of cases, and the action of the poison is slow. He says: “In collecting materials for an account of the snakes of Ratnagiri for the Bombay Gazetteer, I found (in 1878) records of 62 fatal cases treated at the Civil Hospital. These cases showed that death occurred on an aver- age in four and a half days, though in some instances patients had lingered up to twenty days.’ In 1855-56 Dr. Imlach, then Civil Surgeon of Shikarpur, in a description of the ‘ Kapar’ (Echis carinata), published in the Transactions of the Bombay Medical and Physical Society (Vol. iii., New Series, p. 80), wrote that ‘‘a reference to police returns will show that in by far the majority of cases serious injury and death have been caused by the bite of this species.” In an article upon the “ Venomous Snakes of North Canara” (Journ. Nat. Hist. Soc. Bombay, Vol. v., No. 1, p. 69), Mr. Vidal says :—“ Thereis indeed no doubt that the Echis is a far more potent factor than any other venomous _ snake in swelling the mortality of the Bombay Presidency, and _ it is important that this fact should be more generally known and recognised than it has been hitherto. It is, of course, _ impossible to show the exact percentage of the deaths from _ snake-bite for which the Echis is responsible. In the returns no _ attempt is made to discriminate the species to which the recorded deaths are attributable, and little if any reliance could be placed in the statistics, even if such an attempt were made. But the conclusion stated above may, I think, be fairly drawn from the fact, which is very clear from the returns in their present shape, that in all those districts, where the Kehis is known to abound, the average mortality from the snake-bite is markedly high, while conversely, the mortality is insignificant in other dis- _ tricts where the Echis is either rare or absent. The following _ table, which I have compiled with some care and labour from 3 the official returns for the eight years, 1878—85, shows the as ba a ae ' I believe, in these Deccan 100 LABIATZ. population, the actual average mortality, and the mortality per mille of each district in the Bombay Presidency :—~ Average Populetion actual a — Tote? b mortalit Pe District. 7 y mille, Census of from snake- 1878 to 1881, | bite, 1878 | "7685 to 1885 : 1» Hydrabad .....,sececeeee 754,624 18i7 0°247 Thar te Parkar 48°7 0-239 Karac 478,688 87:2 0:18 : atnagiri 997,090 154°5 0-155 Thana 908,548 108:8 07119 aneh Mahals 255,479 30°5 0-119 hikarpur 852,986 72:8 0-085 urat 614,198 415 0-067 EPR Savendsvenie ais ciesbe ees 804,800 47-2 00586 Broach 326,930 19:1 0.0584 Upper Sind Frontier ... 124,181 6°7 0:053 Kolaba 1,649 19-8 0°052 PEE SSE et te ee eee 56,324 39-6 0-046 Sattara 1,062,350 41-0 0038 Cana’ 421,840 16-0 0°037 7 loaum 864,014 30°2 0-034 900,621 18°6 0-020 ) ose : 882,907 17-6 0-019 Khandeish 1,237,231 93-1 0-018 Bijapur 638,493 11:0 0-017 Nasik 781,206 108 0-0138 Ahmednagar | 751,228 10°3.| 0-0137 Sholapur 582,487 2-9 0 003 Thus three Sind districts and Ratnagiri, in all of which the Echis swarms in suitable localities, sional well at the top of the list with an average mortality, taking the four districts togethet : of “205 per 1,000. On the other hand, in the last four districts on the list, ciz,, Bijapur, Nasik, Ahmednagar and Sholapu, the combined average mortality per mille is only -0118. other words only one man dies of snake-bite in about 100,000 in these Deccan districts, while in the Echis-ridden tracts one man dies in every 5,000. Daboias and kraits are probably nowhere so common in Western India as to have much appre- ciable effect on the mortality. But cobras are quite as common, Norse a ey are in el or LABIATA. 101 Sind. This shows, I think, pretty conclusively that the Echis —and not the cobra, or any other venomous snake—is chiefly . responsible for deaths from snake-bite in Bombay.” The fresh leaves of P. parviflorus have a pungent taste, and when bruised are in general use in the Concan as a cataplasm to clean wounds and sores, and to stimulate healthy granulation. | Description.—A stout, erect, branched shrubby plant ; glabrous, pubescent, or scaberulous. Leaves long-petioled, ovate or ovate-lanceolate, singly or doubly crenate-toothed or serrate, 3 base cuneate, whorls subglobose, in dense cylindric or one-sided _ softly hairy spikes, bracts elliptic-ovate, exceeding the hirsute calyx, calyx-teeth short, triangular-lanceolate, ciliate. Nutlets very small, black, shining. The whole plant has a strong black currant odour. Roots woody, knotted; bark light brown, _ scabrous, with an aromatic odour like that of the plant, and a a pungent taste, benumbing the tongue and palate when chewed. Chemical composition. —The most interesting principle detected in the plant was an alkaloid. After repeated purification it was left as a yellow varnish with slightly bitter and mouse-like _ flavour. It was more soluble in chloroform than in ether. _ No special colour reactions were noted. We also detected the _ presence of trimethylamine, and a volatile principle with a _ cedar-wood odour. Resinous principles were also present, with astringent matter. We provisionally call the alkaloid Pogoste- monine. MENTHA SYLVESTRIS, Linn. Fig.—Reichb. Ie. Fl. Germ., t, 82; Eng. Bot. 686. Wild int (Eng.), Menthe sauvage (F.). Hab.—Temperate W. Himalaya, Persia. The herb. Vernacular.—Pudina or Pidina (Hind., Tam., Beng gi, Gus. ), : Chetni-maragu (Can.), Vatalau, Pudina ( (Mar.). History, Uses, &c.—A fragrant plant named pivéa je ivén, in Latin Mintha or Mentha, was known to the Greeks and Romans (Theophr., ii., 4; Plin., 19, 47; 20, Gia which was — 102 LABIAT&. probably a kind of mint. According to Pliny, the name of this plant was afterwards changed to j#dvocpoy on account of the q sweetness of its smell. It was used as an ingredient in sauces and for medicinal purposes ; it is impossible to determine with — certainty which species of mint was used by the ancients, but it 4 is generally supposed to have been M. sativa, Linn. J Ovid tells us that Myntha was a nymph beloved of Pluto, — who was turned into a plant by Proserpine out of jealousy. — De Gubernatis (Myth. des Plant., ii., 226) says:— Les Frangais Vappellent Menthe de Nostre Dame, les Allemands Unser Frauen Miintz, Pietro de Crescenzi, Herba sancte Marie. Dans la Na turale et generale Historia dell’ Indie Occidentali (Ramusio) on lit: “L’herba buona, che in aleune parti chiamano herba santa, e in molto altre menta.’ Dans les Allégories d’.Azz Eddin, traduit par Garcin de Tassy, la menthe semble jouer, au contraire, un assez vilain réle. Le basilic en parle ainsi au jasmin? — “Tu auras peut-étre entendu dire qu’il existe un délateur ( : menthe) parmi les étres de mon espéce ; mais, je t’en prie, ne hut fais pas de reproches; il ne répand que sa propre odeur; il ne di- vulgue qu’un secret qui le regarde; il ne dévoile enfin quece qui peut découvrir.” Quelle allusion peut contenir cette allégorie? Est-il possible que la vieille équivoque latine entre les mots mentha et mentula se soit répétée dans une langue orientale? : Quant a la premiére, elle est certaine, et les poétes porno- graphiques italiens en ont bien abusé. II faut sans doute en- core songer a cette équivoque, pour comprendre Vorigine de la superstition Sicilienne de Caltavuturo, dans la province de Pa- lerme; on y croit que si la femme dans ses mois s’approche de la menthe, la plante périra; autrefois, au lieu de menta, on enten- dait probablement mentula: d’od la croyance qui, autrement, serait inintelligible, = = Apulée, De Virtutibus Herbarum, indique le rite qu’il faut sure pour cueillirla menthe : “Lege eam mense Augusto, mane primo priusquam sol exeat, mundus, ad omnia sic dicens: Te precor, herba hedyosmos, per eum qui nasci te jussit, venias ad me oS OS alla a a * Immovero sic est, aixi idem valet. LABIA? A. 103 hilaris cum tae a ee et effectu tuo, et ea mihi prestes que de a te posco.” Mint does not appear to be mentioned by Sanskrit medical writers. In Arabic @*) (naanaa) and Gi (habak) are general names for the mints, but they are best known as Fuda- _ naj, the Arabic form of the Persian word Pidina or Padang. _ The author of the Makhzan describes three kinds of Fiidanaj, _ wild, mountain, and water mint; the latter, he says, is the Cala- _ mintha of the Greeks. Mountain mint is described as having 4 hoary leaves, but it is impossible from his description to form any opinion as to the exact species to which he refers, The mints are considered to be hot and dry, and are prescribed in dyspeptic affections, fluxes, and dropsy. Different kinds of _ mint are much cultivated in Indian gardens, and are used as _ domestic remedies on account of their stimulant and carminative _ properties. They are often made into a medicinal chutney, q which is eaten to remove a bad taste in the mouth in febrile _ conditions of the body, e.g., Piidina, khérik (dry dates), black _ pepper, rock salt, raisins, and cumin in equal proportions are _ rubbed into a chutney with limejuice. In colic, mint juice with a little black pepper and honey is is given. Description.—W. sy/vestris has leaves broadly or narrowly blong, obovate or lanceolate subacute, serrate, hoary beneath, horls in terminal spikes, calyx-teeth triangular or lanceolate, corolla hairy, glabrous within. Nutlets usually pale, smooth, etimes brown anddelicately reticulate. (#7. Br. Ind.) The plant varies much insize and habit. Aitchison observed Another variety was collected by him on the Harirud valley. : Mentha viridis (spear-mint), M. piperita and M. incana (pep- permint), Jf. sativa, and M. aquatica, oceur in Indian gardens, nd as escapes. M. arvensis is a native of the Western 104, LABIATA. Chemical composition—The most important constituent is th volatile oil, which has the same composition as oil of peppermin but differs from it in odour and flavour (see p. 107). The plant contains a little tannin, Commerce.—The dried plant of M. sylvestris is a reg article of import from Persia into Bombay. Value abou 2 annas per lb, MENTHA ARVENSIS, Linn, var. piperascens. Hab.—China and Japan. The essential oil, and Men! or Peppermint camphor. . Vernacular.—The oil.—Lin-tsao (Ohin.), Hakano Al (Japan), Pédine-ka-tél or atar (Hind. Beng.), Va cha-tél (Mar.), Phudino-nu-tél (Gus.), Pudina attar or -(Tam.), Pudina-attara or tailamu (TZel.), Pudina-attar yanne (Can.). Menthol.—Po-ho-yo (Chin.), Hatsca (J Pudine-ke- phil (Ind. Bazars). : History, Uses, &c.—-Peppermint was in use China and Japan at least 2,000 years ago. The Fuda el-tays, ‘Mentha hircina,” of Ibn Sina appears to have peppermint; he describes it as a very efficacious kind of anda good diuretic. Haji Zein el-attar (1868) men kind of mint called Filfilndn, te, “having the qualities pepper,” also known as Pidinch-i-kohi or “hill mint.” 20 the Arabs and Persians appear to have been well acquainted the value of this mint in neuralgic affections, It is interesti = to observe that in Hull’s British Flora, Manchester, 1799, pepPe mint is named Mentha hircina. Peppermint is not mentioned by Sanskrit writers on Materia Medica. From the Pharmacogré we learn that peper-minét was first observed by Dr. Eales communicated to Ray, who noticed it in his Synopsis in 1 mintsas aremedy for weakness of the stomach and for ¢ 5 Sa _ DABIATH. 105 7 Upon the Continent of Europe peppermint became practically _ known about the latter end of the last century (op. cit., 2nd ed., p. 481). Peppermint camphor was first described by Gmelin in 1829, who obtained it from the European plant. Pereira and 3 Guibourt notice the menthol of China, and in 1862 a memoir on crystallized oil of peppermint from Japan was presented to _the Chemical Society by Oppenheim, who speaks of it as _ coming to Europe in earthenware jars, and often adulterated _ with sulphate of magnesium to the extent of 10 to 20 per cent _ This, however, was not the case with a sample examined by Moss ' and also by G. H. Beckett and C, R. Alder Wright in 1874, _ When first brought to Europe it was used asa remedy for head- 4 ache and neuralgia, and was known in France as Gouttes | Japonaises. In 1879 Mr. Archibald Duncan, a student of the _ University of Edinburgh, drew attention in the Lancet to its _ value as an antiseptic. Dr. A. Rosenberg (Lancet, 1885) recom- ~mended an alcoholic or ethereal solution as a local anssthetic in affections of the nose, pharynx, and larynx. The use of menthol for these purposes has now become general in Europe and America. Dr. Lahnstein (Therap. Monatsh., 1890, No.5) é _has used menthol with striking success against vomiting in a child with traumatic peritonitis where opium and morphine d failed. — cae _ Dr. Drews (Therap. Monatsh., 1890, No. 7) has conditionally eonfirmed the communications of Gottschalk and Weiss con- cerning its value in obstinate vomiting of pregnancy. : Dr. Bronner of Bradford reported at the 62nd meeting of rman Scientists and Physicians in Heidelburg on the success ained by him with menthol (a few drops of a 20 per cent. olution in olive oil poured on pieces of pumice stone) in tinate swelling of the tubes as well as in some cases of lerosis. (Therap. Monatsh., 1890, No. 8.) _ Dr. Jones (Deutsch. Apoth-Zeit., 1890, p- 143) has used “Menthol successfully in 20 per cent. alcoholic solution for ir halation in asthmatic cases. Lastly, the suecess obtained with menthol against diphtheria must be mentioned. _ . wi.“ oo 106 ee LABIAT A. ‘Dr. Hermann Wolff (Therap. Monatsh., 1890, No. 9) has exhaustively reported on his experience of two years with the oil of peppermint, which is largely imported from Chi and Japan. One of us has found a large rectal injection essence of peppermint in warm water afford marked relief renal colic. - Description.—Chinese oil of peppermint is general! high coloured and very pungent, with a bitter after-taste. it from the Indian market. The menthol of China and Ja occurs in long hexagonal erystals, resembling sulphate of r nesium, which contain much water. E. B. Kyle (Amer. Jo of Pharm., 1885) mentions the following among the prope bee ofmenthol. When thrown upon water, currents are produced and from the dissolving crystals. Menthol liquifies with chlor thymol, and camphor ; and this action is particularly noti with thymol, crystals of the two substances placed in eontat being in a few minutes transformed into a thick. oily liqu On gently heating a mixture of 1 drachm of the aqueous sol tion of menthol with half a drachm of a solution of 1 grain iodine and 5 grains of potassium iodide in two drachms of agreeable odour, andon the addition of a little potassi mate becomes chrome-green, the colour remaining unal _ for several weeks. Menthol slightly warmed with nitric yields a thick, wine-coloured, oily liquid, and at a higher heat red fumes are given off; on neutralizing now with ammonia, ® precipitate is observed which is soluble in alcohol, and th solution when evaporated yields an indistinctly erystalli eae ee a cong OE eae EABIAT A. 107 The oil of M. arvensis, var. piperascens, distilled from the fresh plant, grown at Mitcham, by Moss had a decided yellow colour, . and asp. gr. of ‘9107 at 62° F. With the barometer at 30 in, it boiled at 402° F. The sp. gr. of the oil after determining the boiling point, was found to be ‘9117 at 62°F. Other specimens: of cil distilled in England from. the dry im- wrted herb; were found by Moss to be different'in. appearance d physical properties from: that distilled by him, One fabelled “non-rect.” was distinctly green; and had. a sp. gr. of 91 67 at 62°F, ; a second, labelled “‘ rect.,” was pale in:colour, with a faint green tis oe, and had asp. gr. of 9098. The sp. gr. of _ these alls confirm Todd’s generalization that pure coils fall ' between 908 and -917. (Pharm. Journ., p. 446, 1886.) None of - the three oils gave any coloration when subjected to the test a giv en in Todd’s paper above mentioned. It consists in adding’ ene drop of oil to a mixture ef 25 drops of alcohol with one drop ef nitric acid, sp. gr. 1:2. With the oil of M. piperiia a permanent blue er bluish-green colour is developed. | Chemical composition.-—Oil of peppermint owes its peculiar our to menthel (mint camphor, mint stearopten), C!°H°0, sting the oil to fractional distillation. [t forms colourless isms which fuse at 42°C. and beil at 212°C. Distilled th phosphoric anhydride, it yields menthene C!H!8, which a colourless liquid of an agreeable odour. According to loriga {1881), oil of peppermint contains probably leo an of the formula C'°H'®O, which may be prepared from thel by oxidation with potassium bichromate; but by tment with fuming nitric acid menthol yields at first an osive oil, afterward crystals of an acid (C°H°O ty2 H20, melting at 97°C.; this compound is not identical with pyro- ‘tartaric acid, with Viel it agrees in composition. A compound someric with borneol had been found by Beckett and Wright... (1875) in the liquid portion of Japanese peppermint oil, but, So sccording to Fliickiger and Power (1880), is not present in hich is chiefly contained in the last portions obtained on sub- 108 LABIATZ. the oil distilled at Mitcham, which contains, besides menthol, — several hydrocarbons of the formulas C!°H'® andC¥H", and — having a terebinthinate somewhat lemon-like odour. (Stillé q and Maisch.) Commerce.—Chinese oil of peppermint and menthol are imported into India in quarter-catty flat bottles, bearing 4 Chinese label. Four or more of these bottles are packed in a tin box. The Japanese oil is packed in tins of various sizes and has generally an English label, much of it is of very inferior quality, the menthol having been separated. Cocking’s isthe best brand, and is packed in glass bottles with paper cases. Value—oil, Rs. 4 to 5 per lb.; menthol, Rs. 8 per Ib. 4 Indian substitutes for peppermint are Mentha incané, a Wiild., much cultivated in gardens, and wild in Northern Tndia, 4 and Micromeria capitellata, Benth., a native of Behar, the Western Himalaya and the Western Ghats, described by Dalzell as rivalling the peppermint in its aromatic and carm native properties, ORIGANUM MARJORANA, Linv. Fig.-—Woodv. Med. Bot. t. 165. Sweet Marjoram (Eng), Marjolaine (Fr.), Hab.—Portugal to Western Asia. Cultivated in India q The herb. ; 4 _ Vernacular.—Marwa (Indian Bazars). 4 _ History, Uses, &c.—The name op/yavov, in modern Greek a -Ptyars, Was applied in ancient times to plants of this genus, but - O. marjorana was distinguished by the names capyvuxov aD spapaxes, A Greek myth informs us that Amaracus was a page to the king of Cyprus, who one day on letting fall a vessel of perfume became so frightened that he was turned into this plant. The Greeks and Romans decorated the newly married with it. Catullus says :— Cings tempora floribus LABIAT&A. 109 It is the Marjolaine of the French. De Gubernatisstates that in Southern Europe it is the symbol of honour and the protector of married women. It is the Maruva and Jambhira of the Raja Nirghanta and the Marwa or Marzangush of the Persians, Ibn Sina calls it Marzanjush. The Persian word signifies *‘mouse-ear,”’ a name given to it on account of the greyish downy character of the leaves, which is more marked in the Persian variety than in the European plant. Marjoram is cultivated as a pot-plant in most Indian gardens, and is used as a substitute _ for thyme in cookery. At Bandora, near Bombay, it is grown as a garden crop to supply bouquets for the Bombay market, which are much worn by women in their hair. The medicinal uses of Marjoram in the East are similar to those of mint. Description,—An annual herb. The leaves are spatu- late or oval, very obtuse, entire, gray green, soft-hairy, and pellucid punctate. The flowers are aggregated in small heads © and have a small whitish corolla. The plant is agreeably and pungently aromatic. Chemical composition.—The volatile oil (Oleum majorane) is thin, yellowish, of the specific gravity 0:89, boils above 163°C., __ is readily soluble in alcohol, has the aromatic odour of the herb, — and, according to Beilstein and E. Wiegand (1882), contains a terpene boiling at 178° C. and forming a liquid compound with HCI; the fraction boiling between 200° and 220° C. has the | _ composition C'*H*60, and is not affected by metallic sodium. _ (Stillé and Maisch.) THYMUS SERPYLLUM, Linz. Fig.— Engl. Bot., wvii., t. 1514. Wild Thyme (Eng.), Ser- polet (Fr.). Hab.— Western Temperate Himalaya, Persia, Europe. The herb. Vernacular.—Masho (Panj.), Hashé (Pers. Ind. Bazars). History, Uses, &c.—Hishé is the Persian name of ce T. serpylium, but it has been adopted by the Arabian and Persian 110 LABIATAE. physicians as the equivalent of the 6%pos of Dioscorides, a plant concerning the identity of which there is much doubt: some supposing it to be the Satureia capitata of Linneus, and others the Thymus vulgaris or T. Zygis of the same botanist. Ibn Sina in his description of Hash& quotes what Dioscorides says con- cerning pos, and does not notice the éprvAdos of the same author — usually identified with 7. serpy/lum, Haji Zein el-Attar follows Ibn Sina in identifying Hashé with the ios of the Greeks, and describes it as a kind of mountain mint with very numerous small flowers of a purplish colour, slender stems, and leaves lik the Jadeh. His description of its medicinal properties hardly differs from that of Pliny (21, 89), which is as follows: —“ Thyme it dispels chronic fluxes of the fauces, ag well as various affections of the, stomach and bowels; still, however, it must be used in moderation, as it ‘is of a heating nature, and acts as an astringent on the bowels. In cases of ulceration of the intestines, the dose should be one denarius of thyme to one sextarius of oxymel ; the same proportions, too, should be taken for pains in the sides, between the shoulder-blades, or in the thoracic organs. Taken with oxymel, it is used for the ewre of intestinal diseases, and is administered in cases of alienation of the senses and melancholy. Thyme is given also for epilepsy, ‘when the fits come on, the smell of it reviving the patient; it is said, too, that epileptic persons should sleep upon soft thyme. It is good also for hardness of breathing, and for asthma and obstructions of the catamenia. A decoction of thyme water, boiled down to one-third, brings away the dead foetus, and itis given to males with oxymel, as a remedy for a flatulency, and in cases of swelling of the abdomen or testes and. of pains inthe bladder, Applied with wine, it removes tumours — and fluxes, and in combination with vinegar, callosities and warts. Mixed with wine, it is used as an external application ~ LABIATZ. 111 for sciatica; and beaten up with oil and sprinkled upon wool, it is employed for diseases of the joints and for sprains, It is applied also to burns, mixed with lard. For maladies of the joints of recent date, thyme is administered in drink, in doses of three oboli to three cyathi of oxymel. For loss of appetite it is given beaten up with salt.” oe eR eT ss lela ie 3 eye The ancients appear to have been acquainted with the anti- septic properties of thyme. . Virgil (Georg. IV., 241) speaks of the fumigation of beehives with the smoke of the burning plant, and the name @vyos is derived from 4%, to burn incense. Macer Floridus (De Vir. Herb) recommends thyme as a remedy for the bites of venomous animals. In the Punjab the seeds of 7. serpyl/um are given as a vermifuge. (Stewart.) The plant is an indifferent substitute for 7. oulgaris, as it contains hardly any thymol. The latter principle is, however, afforded abundantly by the seeds of Oarum copticum, a plant _ largely cultivated in India. Thymol is a powerful antiseptic ; when absorbed it paralyses the nerve centres in the cord _ and medulla, and like carbolic acid lessens reflex action; _ slowing the respiration, and lowering the blood-pressure and temperature. In poisonous doses it causes weakness, _ drowsiness, coma and death. It differs from carbolic acid in being less volatile and less easily oxidised. Its action as a disinfectant is more permanent and at the same time more powerful than that of carbolic acid. It is less irritating _ to the skin or mucous membrane, and does not act as a eaustic like carbolic acid, and is a less powerful poison to ammals. Its action on the nerve-centres is a paralysing one from the first, and is not preceded by excitement as in the case f carbolic acid. While in the body it appears to effect tissue- ‘metabolism, for in animals poisoned by it the liver is found quite fatty, as in phosphorus-poisoning. It appears to be elimi- nat by the respiratory and urinary organs and rane is extremely congested, the secretion of mucous increased ce ae lungs congested, and sometimes consolidated; the kidneys EY2 LABIATA, inflamed, and the urine albuminous or bloody. Thymol has ‘ been used as an antiseptic, as an application to skin diseases, ringworm, eczema, psoriasis; as a gargle, spray, or inhalation in sore-throat, bronchiectasis and phthisis, or as an injection imozena. Internally it has been usedin diabetes and vesical — eatarrh. (Lauder Brunton.) _o Dr. Gross (Pharm. Zeitsch., 1890, p. 261) reports on the sue- cessful results obtained with thymol in the treatment of diph- theria, having found it the most effective remedy in 280 cases. He prescribed, according to the age of the child, a 0-1 to 0°3 per — cent. solution in doses of 10 to 12 drops every 5 to 10 minutes, according to the severity of the case. The solution was flavour- ed with some pleasant-tasting syrup and in severe cases a few — _ drops of brandy were added. The children soon become accus- ™\ LABIATAE, 113 _ has an aromatic thyme-like odour and a warm, pungent but _ scarcely caustic taste. It dissolves sparingly in water, requiring _ its weight of alcohol, ether, and chloroform, in 2 parts of soda solution sp. gr. 1:16, and freely in benzol, benzin, carbon _ disulphide, glacial acetic acid, and fixed and volatile oils. It | forms with soda a crystallizable and readily soluble compound, and does not change the colour of a solution of ferric chloride. Symes (1879) ascertained that on being triturated with one-half rt fo ten times its weight of camphor, a colourless syrupy liquid is 3 “obtained, butit does not liquefy with chloral hydrate. According _ to Gerrard, the strongest aqueous solution of thymol available is 1 in 1,000, and a solution of 4 grains of it ina fluid ounce of _ alcohol is miscible with water without becoming turbid; _ 3 grains of thymol are dissolved by 1 grain of caustic soda and 4 1} grains of caustic potash. Solid fats, when heated, are 4 excellent solvents of thymol. A solution of 1 part of thymol _ in 100 parts of warm glycerin remains clear. Thymol is also soluble in 4 parts of cold sulphuric acid; the solution has a 3 ‘yellowish colour, and, on being gently heated, becomes rose-red. the mixture with an excess of lead carbonate, and filtering, , e liquid becomes violet-blueon the addition of ferric chloride. This reaction is due to sudphothymoliec acid, C'°H"*SO’, discovered By Lallemand (1853). Hammarsten and Robert (1881) give the following as the most delicate test by which one-millionth thymol may still be detected: Mix the liquid with oue-half its volume of glacial acetic acid, then with at least an ual volume of sulphuric acid, and warm gently, when a bright lish-violet colour is produced which is not destroyed by ing. Acco ceording to Hirschsohn (1881), a solution of thymol 60,000 parts of water is rendered turbid by bromine-water, ut, according to Hammarsten, the precipitate is not crystalline e tribromophenol, (S¢il/é and Maisch.) Chemical composition.—The volatile oil of Thymus Serpyllum, 11L.—16 at 15° C. 1,100 to 1,200 parts for solution, but is solublein half - n pouring this solution into 10 volumes of water, digesting — n.» according to EH. Buri (1879), contains two phenols which not congeal at—10° C., and of which one imparts a relletiaies 2 ~ - atl1d5° C. was 0°917. , _ describe it as having properties similar to those of thyme and — ae mint. Dr. J ayakar of Muscat found the plant in flower in 114 LABIATA, green colour to ferric chloride, and yields a sulphonic acid, the 4 salts of which, like the thymol sulphonates, produce with ferric salts an intense blue colour. Jahns (1880) reported also the 4 presence of a little thymol and carvacrol. Messrs. Schimmel a & Co.(Report, April 1891) obtained by distillation of the leaves and stalks 0-3 per cent. of an oil having a very pleasant melissa a like aroma with a slight soupcon of thyme. Its specific gravity Thymus vulgaris, Linn., is the chief source of thymol i in Europe; upon Carum copticum. (Vol. ii., p. 116.) - Féidanaj-i-jibali, also called Pudineh-i-kohf, «hill mint,” is identified by Mahometan physicians with the Calamintha of re ancients (cf. Matth. Vaigr. v., 2, 76. J), Calamintha culgaris; Sweet, Hng. Bot. 1676. We bees not met with this drug in the Indian Bazars, but three species of Calamintha occur in the Himalayas. ZATARIA MULTIFLORA, Boiss. Hab.— Arabia, Persia. The herb in flower. Vernacular.—Saatar (Ind. Bazars). _ History, Uses, &c.-—The Mahometan physicians of the East identify this drug with the épiyavey of the Greeks, May 1885. on the hills near Muscat in Arabia, and kindly forwarded specimens, which were identified at Kew as Z. multi- flora. The drug i is much used in India in infusion 2s aD agreeable aromatic stimulant and diaphoretic; many other properties are ascribed to it in Persian medical works which it is unnecessary to recapitulate. LABIAT&. 115 q and numerous minute flowers, forming knotted clusters upon a _ slender spike ; each flower is furnished with a small bract, and ' when magnified the bracts and calices are seen to be densely _ eovered with jointed hairs. The calyx is unequally 4-cleft, the 4 corolla labiate, and of a red colour, the calyx and flower after q being soaked in water for 24 hours only measured 4 inch in length. The leaves when magnified present a mossy surface, hich is thickly pitted, each pit containing a granule of red, sinified essential oil. Chemical composition.—The leaves contain an aromatic essen- — al oil having a minty odour, a red, tasteless, acid resin, and some tannic acid giving a green precipitate with ferric chloride. - The bitterness is not due to an alkaloid, The leaves containing 10 per cent. of moisture yielded 15 per cent. of ash. ZIZIPHORA TENUIOR, Lina. Hab.—Persia, Beluchistan. The herb. Vernacular.—Mishk-i-taramashia (Jnd. Bazars). History, Uses, &c.—The Mahometans of the East d dry. Haji Zein in the Ikhtiardé states that it is called == ng in Shiraz, and that the milk of poats feeding upon it omes bloody. He describes it as a valuable expectorant and uses hematuria. He also mentions its use by Galen asa ppository in painful affections of the uterus, and by Ishak asa rininative addition to purgative medicines. The drug is also to be a powerful aphrodisiac. 2 oats states that the Description.—A very small plant, 2 to 3 inches high ; t as long as the plant, single, woody, with a few small fibres. The stems, which are 2 to 5 in number, are also woody, and branch from the ground; they are thickly set with jonree and entity this plant with the fvys or “wild thyme” of theGreeks. is the eso! yhSi.0 of Ibn Sina, who describes it as very hot 116 LABIATA, flowers, which reach to the apex and form a spike. The leaves 4 are linear-lanceolate, and have several prominent straight veins — on each side of the midrib. The calyx, which is purple, . encloses four oblong seeds of a brown colour, and is marked with . numerous ribs, and ends in five sharply cut claws; it is studded 4 with simple hairs, and is 3,ths of an inch long. The odour — and taste of the drug is pleasant, like peppermint, but sweeter. Zufah-i-yabis.* From an examination of the drug it which, is woody; root woody, seldom branched; flower heads — numerous, oblong; calyx striated, hairy, purple, with five sharp teeth ; seeds naked, four in number, oblong, 3-angled, of a pale : brown, studded with rows of small round tubercles ;on one side — of the hilum there is a fringe of smaller tubercles very closely set, and on the other two elongated. white prominences. AS found in commerce the plant is much broken up; it has a pleasant Odour like sweet hay. Taste bitter ; properties, according to native writers, stimulant, anthelmintic, and deobstruent. The drug is generally attributed to Hyssopus officinalis, OD _this cannot be correct, as the flowers are in oblong spikes. {tis imported from Persia, se -€ a. Parviflora, Benth., is a native of the temperate Himalaya. = Chemical composition.—Besides tannin, resin, fat, sugar, mucl- tage, &c., the most important constituent of Hyssop is ot/ of : _hyssop, of which the fresh herb yields } to 4 per cent. It 18 pale-yellow or greenish, limpid, of about the specific gravity 0°94, and freely soluble in alcohol; it contains oxygen, and com-— mences to boil at 142°C., the boiling-point rising to 180°C. It has the odour and taste of the herb. The hyssopin of Her- berger (1829) was found by Trommsdorff to be impure sulphate of calcium. ne * Sibthorp states that Satureea price, Linh; is the ccuxe of WE Tatil daa 22 on pe el nei me! r, DA BI ATH. 1 17 Badranjboya, © Baklat-el-Utrujiya (Arabd.). Imported from Persia. ao Description.—Calyx striated, hairy, 5-fid, not so long as that of Zifah-i-y4bis, and not coloured; seeds four, naked, brown, 8-angled, nearly smooth, a white patch on each side of the hilum; flowers in axillary clusters of about 6, upon a short peduncle; leaves ovate, margin deeply dentate, somewhat hairy. The drug is always much broken and consists chiefly of stem and fruit; the former is quadrangular, much larger than that of Zifah, of a purplish tint. Taste bitter, odour faintly aromatic. This herb is supposed to represent the pedrcoodvddov of Dioscorides and Theophrastus, generally known in Latin as Apiastrum. Virgil (G. 4, 63) calls it Melisphylla, and Theo- phrastus (4, 25) evodns pedirera. It is a plant beloved by bees, the Balm Gentle or Melissa officinalis of our gardens. When fresh it has a pleasant lemon odour, which is not retained by the dry plant. It was formerly valued as a corroborant in hypochon- driacal affections, and the Persian drug is still used for this purpose by Indian hAakims. In Europe, Balm tea is still a domestic remedy, and is given as a grateful diluent in febrile affections: it has a place in the French Codex. The different species of Melissa are widely diffused, being found in note, Central Asia, and North America. Chemical composition—The leaves of I. officinalis contain, besides the common constituents of plants, a small quantity of tannin and bitter principle, and about } to ¢ per cent. of volatile oil, which is colourless or yellowish, has a specific gravity of about 0°89 ; dissolves in about 5 parts of alcohol, sp. gr. 0- 85, and contains a stearopten. ee Mee ee MARRUBIUM VULGARE, Linn. - Fig.—Reichb. Ic. Fi. Germ., t. 1224, J- 1; Eng. Bot. , 410; Bent. and Trim., 210, es White Horcksnnd (Hing.); rube blane (F'’r.). Hab. — Western Temperate Selarsto Bas The herb, Vernacular.— Farasiytm (Ind. Bazars), 3 118 LABIATH. History, Uses, &c.—This plant is the gpéowy of Theo- phrastus(vi., 2), who mentions twokinds. Dioscorides (iii., 110) relates its medicinal uses, which are also noticed by Hippocrates (681, 3), Celsus (v., 11), and Pliny (20, 89). The ancients — considered it to be a general stimulant, expectorant, deobstruent, — carminative and local anodyne. Horehound has still a consi- derable reputation in Europe as a remedy for chronic bronchitis with Copious expectoration, and as a stomachic tonic in dys- expressed juice with honey, both internally and as a local appli- cation to foul ulcers and diseased mucous surfaces. Horehound is the Fardsiyin of Ibn Sina and other Arabian physicians, who reproduce the account given by Dioscorides of its medicinal uses. Hakim Ali Gildni, in his commentary upon the Kanun, gives Saf-el-ard, ‘‘earth wool,” and Hashishat-el- kalb, “dogs’ herb,” as Arabic names for the plant; he Bays that dogs always piss on smelling it. s Owing to the similarity between the Greek words tpaovor and Muatamid-el-muluk Syud Alyikhin points out this error, but falls into another, inasmuch as he identifies it with Arusa- (Adhatoda Vasica). Mahometan writers also mention a second kind of Far4siy(n called Baliti; this is our Black Horehound (Ballota nigra, Linn.). e M. vulgare is a common plant in Persia; Aitchison observed it growing abundantly i in Khorasan, In the bazars of the plains” of India it is not obtainable; if demanded, either Arusa, oF 4 kind of squill called Farésiy4n-i-piydzi, is supplied. Description. —The branching stem is about a foot high, rangular, much-branched, and covered with a white felt. The leaves are opposite, petiolate, about an inch long, roundish- ovate, somewhat heart-shaped or rounded at the base, obtuse, serrate or * coarsely crenate, wrinkled by the pong 7 LABIAT&. 119 7 pale-green and downy above and hoary beneath.. The flowers are in dense axillary whorls, with woolly, linear, and hooked bracts, a tubular ten-ribbed calyx divided into ten short, spreading, stiff, and hooked teeth, and a white bilabiate corolla enclosing four stamens. The four achenes are dark-brown. The herb has a peculiar aromatic and somewhat musky odour da pungent bitter taste; if kept for any time, the aroma dis- pears. Chemical composition.-—The plant has been recently examined y J. W. Morrison (Am. Journ. Pharm., 1890, p. 327). A roximate analysis gave the following result :— Per cent. Fat, wax and traces of volatile oil .....c...... sesseesee 2°05 Crystalline compound, soluble in ether ..............- “48 BPRAOPODEY! B50 TAG ele, cece tesisis sanconceniess crednas 2°29 Resin and bitter Ses aoe soluble in absolute alcohol 1°94 4°94 . 67 Extractive, soluble in water 5-93 Albuminoids 4:48 Pectin and undetermined antes . §93 2°30 Cellulose and lignin 37°48 6°72 ie 24 30 "49 The fat was soluble in hot 95 per cent. alcohol, and melted at. 6° C. The wax was insoluble in this solvent, but dissolved in carbon bisulphide. The crystalline principle was extracted from the drug with stronger ether, and purified by repeated atments with animal charcoal. The crystals were it sol erystallization from hot 95 per cént. alcohol, with one or more — te 120 | LABIATA. in water and in solution of potassium hydrate, very sparingly” 4 soluble in boiling water and in cold alcohol. Soluble in hot — 95 per cent. alcohol, also in ether and chloroform. They melted at 152° to 153° C. They were at first tasteless, but developed, when held on the tongue, a decided bitterness. The alcoholic solution was very bitter. Sulphuric or nitric acid gave a dark-brown colour, hydrochloric — acid produced no change and ferric chloride produced no change. This principle: reduced Fehling’s solution slightly by boiling, then on heating with Fehling’s solution an abundant precipitate of cuprous oxide was produced, thus showing it to be an easil, decomposable glucoside. A small quantity of a bitter principle was extracted from the drug by absolute alcohol, along with the resin. This appeared to be different from the previous one extracted by ether, for the purpose of further investigation, a larger quantity e drug was exhausted with ether, the solvent recovered the residue treated with petroleum ether to remove fat and W The remaining portion was dissolved in hot alcohol, trea with animal charcoal and crystallized. The crystals were pa fied by repeated crystallization and treatment with a charcoal. Melting point, 152° to 153° C. The Srerene of two combustions was:— Found. Calculated fore = (C+0H*80°) 20-95 70°38 eee 8:42 8-50 Oe 21°33 PA ie B: 100-00 100°00 Three samples of rystals, presented with a thesis of last yeat oe by Frederick G, Hertel, Ph.G. (American Journal of Pharmacy 1890, p. 278), and obtained by. him from the fluid extract, ¥ LABIAT A. 121 Bis: examined, One of these, which e had crystallized from 4 cold aleohol, melted at 153°5° to 154°5° C., was evidently near = ure ; the Ayetnge: of three combustions —— Cc 70°54 H a , B 9-08 O | 3 20°38 100-00 The other samples were evidently the same compound in an mpurer condition, as was found by combustion and melting point. The author here remarks :— ; “This compound as well as that obtained by myself is - evidently the marrubiin discovered by Mein in 1855. Harm (Archiv der Pharmacie, No. 83, p. 144) stated the melting point be 148°C. “Tn a later communication (No. 116, page 41), on elementary nalysis he found the substance to contain 8°52 per cent. of . ydrogen and more than 69 per cent. of carbon. “Kromayer (Archiv der Pharmacie, No. 108, p. 257). ‘gives e he yield of marrubiin as about 2 grams from 25 pounds of the hat itis not a glucoside. My results indicate its. composition o be very close to that of absinthiin, C*°H®*0°, but they do not” gree with all the properties of that substance as described by bsinthiin melts at 120°to 125° ©. Many of the properties, ever, are common asd both = prominent ‘among he residue treated with water and filtered. The filtrate, on agitation successively with ether and chloro 2 form, yielded to the former a. very. bitter = substan —TIL—16 g, and states the melting point to be about 160°C.,. and ae angled; leaves ovate-lanceolate, crenately serrated at the uppé a 2a about 5 inches long, and 13 inch broad; cal ; 122 LABIAT. with a narcotic odour, and to the latter a brownish substance especially after heating with dilute acid, during which process to the presence of two bitter principles besides marrubiin, whie isin agreement with Hertel’s statement, that after the separatio of marrubiin the fluid extract appeared to be as bitter as bef Anisomeles malabarica, Br. Bot. Magq., t. 2071 Wight Ic., t. 164, is well known in Southern India, where i called Peyameratti in Tamil and Mogbira in Telugu. phius, speaking of the juice of the plant, says:—“ Idem begat succus cum binis guttis olei sesamini propinatus, prodest mirifi asthmaticis, vel tussi mala laborantibus, quem in finem syru quoque preparatur ex foliorum succo cum saccharo cocto. (Hort. Amb. v., 8,65.) It is a native of Malabar, where | is called Karintoomba, and is noticed by Rheede. (Hort. Mal. p- 185, #93.) ‘Wight, Ainslie, and others mention that infusion of the leaves is given to children in colic, dy oP and fever arising from teething; in ague an infusion of leaves is used to promote perspiration ; a decoction of the or the essential oil distilled from it, is used externally rheumatism. The plant appears to have medicinal proper very similar to those of Horehound. Description.—Shrubby, 2 to 5 feet; branches ob =e) 5-cleft, thickly covered with long white rather viscid pubescence upper PI er lip of corolla entire, white, under one 3-cleft with the lateral divisions reflexed ; anthers deep purple ; whorls dispose in simple racemes, LEUCAS ASPERA, Spreng. _ Fig.—Rheede, Hort, Mal. x., t. 91. s Hab.—Plains of India, The herb. LABIATA. 123 LEUCAS LINIFOLIA, Spreng. — ~-Fig.—Jacg. Ie. Pl. Rar. i., 11, 4. 111; Rumph. Herb. _ Amb. vi., t. 16, f. 1. Hab.—Plains of India. The herb. LEUCAS ZEYLANICA, Br. Fig.— Wight Il., ¢. 176. Herbe Tombée (Fr.). Hab.—Assam to Ceylon. The herb. LEUCAS CEPHALOTES, Spreng. Fig.— Wight Ic., t. 337; Desf. in Mem. Mus. at., 8, t. 4. : Hab.—Himalaya. Plains of N. India and Deccan. The 4 herb. —~ Vernacular. —Ttimba-phél, Kimbha-phil, Bahdphili (Mar.), - Goma, Madha-péti (Hind.), Tigadi (Can.), Kibo, Kélén-né-phiil _ (Guz.), Tumba (Mal), Gul-dora, Chatra (Punj.), Halkasa (Beng.), Tumi (Zvi,). : History, Uses, &c.—At least four species of Leucas are used in Hindu medicine under the Sanskrit name of Drona- pushpi or “cup-flower,” so called from the resemblance of the calyx of these plants to a little cup. The synonyms for these plants are Kumbha-yoni, Kurumba, Kharva-yattra, Chitra- | pattrika, Chitrékshupa and Su-pushpa ; they are described in the Nighantas as heavy, dry, sweet, hot, and aperient, generators # wind and bile, and are prescribed for jaundice and to expel phlegmatic humors and worms; they are also considered to be timulant and diaphoretic. _ In the cough or catarrh of children, Tumba juice 1 part, - ’ with 2 parts of honey and a few grains of Borax, may bemixed, 4 and in intestinal catarrh 124 - LABIATAi. These plants are also used in Hindu-ritual ; during-the cere monial bath, early in the morning on the Naraka Chaturdasi, first day of the Divali, the religious manuals direct the whirlin, round the body, while bathing, of a sprig ef Drona- spushpt Re anthes aspera (apamarga), and of Cassia Tora ( prapund Vol. IL., p. 65. The Mahometan physicians have given th ae the name of Siséliyis, and use them as a substitute Rheede notice’ the use of L. aspera in Malabar, and the sam species is given in amenorrhea at Réunion. Under the name¢ Herba admirationis a species of Leucas, probably L. linifolia, _ described by Rumphius. In Western India JZ. zeylanica 7 much used, and in the Punjab D. eephalotes. These plants a popular local application to itch and mange, and the the leaves snuffed up by the nostrils is used as a remedy in bites, and for headache and colds. An infusion is known insecticide, and planters and others on the Nilgiris find that and insect pests may be kept away from trees by a dt application of this remedy. The flowers are offered i ' Hindu temples. In Réunion L. zeylanica is known as F Tombée, and is considered to be stimulant and antirheuma eto - Description.—L. aspera is annual, erect or diffuse stout, hispid or scabrid, leaves 1 to 3 inches, linear or © ichttia, entire or crenate, whorls large, terminal and a3 bracts long, linear and filiform, calyx } to ¢ of an inch, t lar, = smooth below, green and ribbed and scabrid aboy tracted above the nutlets, mouth small, glabrous, - flowers ese plant Dead-nettle (Lamium cin but D. aspera is more 2 fra than the others, | * : ; iteniéal avr afforded a very. decoction of the herb DLABIATHA, | 125 "given off, and on sondeeeie the vapour, ammonia and a volatile : alkaloid were detected in the distillate. The alkaloid was com- _ bined in the plant with an acid giving a green colour with ferric salts, The air-dried plant afforded 7°3 per cent, of ash. Leonotis nepetzefolia, Br. Bot. Reg., t. 281; WightIe. i £.867; Vern. Fee and (Beng. oa oot Matisil (Guz. )>. ‘It is easily recognised by its globular spinous heads of orange-coloured flowers. Roxburgh gives the following description of the plant:—“Stem anual straight, four-sided, simple, from 4 to 6 feet high. Leaves opposite, spreading, _ petioled, cordate, serrate, pointed, downy, from 4 to 8 inches long, and 2 to 3 broad. Floral leaves (dractes verticillorim) - the plant about 5 inches asunder. Involucres many, subulate: Flowers numerous, of a deep rich orange colour. Calyx, 10-striated, 8-toothed ; corol, under lip ~~ short, eencesaie at all times of a dirty withered colour.” ge O _ The ashes of the flower-heads mixed with curds are aie Be to ringworm and other itchy diseases of the skin. Dr, A. Fee at a decoction of the leaves is used as a tonic, the juice is also pressed and taken with limejuice. and rum asa febrifuge. r, Amadeo has used it in- combination with Piglanthas truri in intermittents. , uliun (odor ), the Poly-Germander ( Teucrium Polium, L. ‘ skurdiyun (cxop8iov), the Water-Germander (7. Scordiumy, and Kamazariyus (xa#ddpus), the Wall-Germander (7. Chamcedrys), are treated of in the Materia Medica of the Indian Mahometan physicians, but none of these plants are, as far as ant has an odour of garlic, and i is one of the augdienie t. Amadeo states that it is called. Rascamoito i in Porto-Rico, ‘and r experience goes, obtainable in the bazars, although x Score — un is a native of the Western Himalaya and Cashmere. This: a (126 PLANTAGINE. j Tiryak-ieFarik or Theriaca Andromachi, which is still sold in — the bazars of India. T. Polium is a native of Persia, and was 3 found by Aitchison in Khorasan, but he did not observe that it was used medicinally. He also notices 7. serratum, Benth., as having a strong odour of asafcctida. 7. Chamedrys was formerly used in Europe as a remedy for gout, and was an ingredient in the celebrated antiarthritic or Portland powder. PLANTAGINEZ. PLANTAGO OVATA, ssk. Fig.—-Benti. and Trim., t.211. Syn. P. Ispaghula. — Hab.—Punjab, Sind, Persia, The seeds. Spogel s (Eng.). Vernacular.—Isbaghol (Hind.), Esabgol (Mar.), Eshop: ol ( Beng.), Esopgol, Uthamu-jirun ( Gus.), Ishappukol-virai (TZ Isapagéla-vittulu (Te/.), Isabakolu ( Can.). | History, Uses, &c.—The seeds are not mentioned : the old Hindu writers, but the Guzerathi name appears to be | Sanskrit origin. In all the vernaculars corruptions of t Persian name Jspaghil are in use. This word is a compe ! of y! ‘a horse,” and Js “the ear,’’in allusion to the shape the seeds. In Mahometan works the seeds will be f described under thename of Bazr-i-Katina. The author Makhzan states that Kalién is the Greek, Isparzah the Isfah and Bangist and Shikam-daridah the Shirazi names for | In India, they are considered to be cooling and demulcent, am useful in inflammatory and bilious derangements of the di tive organs. The crushed seeds made into a poultice with vi garand oil are applied to rheumatic and gouty swelli With the mucilage a cooling lotion for the head is made. to three dirhems moistened with hot water and mixed sugar are given in dysentery and irritation of the ix PLANTAGINEA. 127 _ canal to procure an easy stool, The decoction is prescribed in a cough. The roasted seeds have an astringent effect, and are use- ful in irritation of the bowels in children, and in dysentery. _ The natives have an idea that the powdered seeds are injurious, and consequently always administer them whole. Fleming, wining, Ainslie, and others speak very favourably of the use of Ispaghil in the treatment of chronic diarrhea. Twining ives the dose for an adult as 24 drachms mixed with half a achm of sugar-candy. (Diseases of Bengal, Vol. I., p. 212.) n the Pharmacopwia of India the seeds have been made fficial, and directions are given for the preparation of a decoction. Description.—The seeds are boat-shaped, about { of an inch long and rather less than +; broad, translucent, with a pinkish tinge and a faint brown streak upon the convex side. Thecon- avity is covered with a thin white membrane. Soaked in water is free from taste and odour, The epidermis of the seeds is omposed of polyhedral cells, the walls of which are thickened y secondary deposits, the source of the mucilage; between ¢ and the albumen is a thin brownish layer. The albumen | formed of thick walled cells which contain granular natter. P. amplexicaulis, Can, tes it., t. 125, a plant of the unjab Plains, Malwa and Sind, extending to Southern Europe, arnishes the brown Ispaghdé/ not unfrequently to be met with the Indian bazars. The seeds have the same boat-shaped m as those of P. ovata, but are rather larger, averaging f an inch in length. They are probably as efficient as the true aghil seeds. Commerce.—Large quantities of these seeds are imported ~ nto Bombay from Persia. Value, Rs. 4 per maund — : 74 Ibs. They differ in colour, some being brown and some nearly ite-with a pinkish tinge; the latter are prelee 428 PLANTAQINEEE. PLANTAGO MAJOR, Linn. Fig,— Wight Iil., t. 177; Eng. Bot., 1558. Greater Pla tain (Zng.), Grand Plantain (F*.). Hab.— Temperate India, Persia, Europe. The seeds. Vernacular,—Bartang, Barhang (Indian bazars). History, Uses, &c.—Under the name of apyoyAcaoor corides describes two varieties of Plantago, the greater and Jesser, and states that the first is the best and most gen ‘used. - These plants were known tothe Romans as Plantago, according to Sibthorp are the P. dagopus and P. altiss modern botany ; they were considered to be very effectu arresting the fluxes known by the Greeks as “rheuma or “‘griping pains in the bowels” (Plin. 25, 39 ; 26, 47). leaves and roots were considered to be astringent an fuge (Galen). The Arabian physicians describe them ‘the name of Lisén-el-hamal, and state that they ‘Sabaat-azlaa and Kasrat-el-azlaa of Dioscorides (Arabi lations of énrdmevpor, and mohvvevpov) meaning ‘ seven: ‘many-ribbed’ ; they repeat what the Greeks have wie! few trifling additions. The seeds of P. : -was cured by these seeds when suffering from the disease d _ his travels in-Khorasan. The root and leaves are still _ Europe as domestic remedies on account. of their m i properties The seeds of P, Psyllium, fon. a native of the ‘Punjab, extending to Southern Europe, are used in a manner. This plant is often stated to be the source | Persian: Birhang, ae we pays ae obtained . _sowing these seeds. _ Dipactintias Stn eed are rata ‘aerkerg with waved, sin apa sslerniede) 3 dar ker PLANTAGINEE. 429 _ with a scar showing the attachment to. the ovary. They are insipid, and have an oily smell when crushed. Soaked in water they become coated with a transparent mucilage. Chemical composition.—The leaves of P. major have been examined chemically by Dr. Rosenbaum, but the results _ obtained do not indicate any active principle. He found that petroleum benzine extracted 4 per cent. of wax and chlorephyll, - the extract fusing at 83° C. Ether dissolved 4:4 per cent. of 2 resin and chlorophyll. Alcohol extracted 10 per cent., of which _ 6 per cent. was soluble in water and contained a considerable ~ amount of sugar; the remaining four parts were soluble in ammonia. Watertook up 13 per cent.,of which 7-2 per cent. was insoluble in 66 per cent. alcohol. Soda solution dissolved 6 per cent., and diluted acid 10 per cent., the latter containing a notable quantity of calcium oxalate. It may be noted here that Th. Koller, in 1868, found citric acid and oxalic acid in the _ three species, P. major, P. lanceolata, and P. media, besides the _ ordinary plant constituents, chlorophyll, resin, wax, albumen,and pectin. These constituents do not account for the reputation as a styptic and vulnerary in which the plant was held by ancient writers. The presence of sugar indicates the possibility of a _ glucoside being contained in the plant. The value of the seeds in diarrhea and dysentery is no doubt due in some measure to the quantity of mucilage they afford. (Amer. Journ. Pharm., Sept., 1886.) __ Plantago mucilage is neutral in reaction, is not altered by iodine or precipitated by borax, alcohol, or perchloride of iron. It is only sparingly soluble in water. Sa dat sgt ompound with phenylhydrazine. Wood-gum can be obtained soda and precipitating with alcohol and HCl. When this is hydrolysed, it yields Koch’s wood-sugar or xylose. Xylose sely resembles arabinose in all its properties, and, like Ul.—17 | , like trom beech wood, jute, or deal, by extracting with 5 per cent. _ os a NYCTAGINEH. latter, is dextrorotatory ; when treated with acids, it yields consi- derable quantities of furfuramide, but no levulose. The pheny 4 osazone has the composition C!7H®°N40%, so that xylose is 4 penta-glucose C°H?°O5, When treated with nitric acid, it is obtained, give thecherry-red coloration of arabin when warmed with phloroglucinol and hydrochloric acid. This reaction’ oat be employed for the detection of xylose and arabinose, (Journ, Chem. Soc., LVT., pp. 233, 847.) NYCTAGINE. BOERHAAVIA REPENS, Linn, Fig.—Delile, Fl. £4., t. 3, f.1; Wight Ic., t. 874; B. Hort. Mal. vii., t. 56, Spreading Hogweed (Hng.), Pa (f*.). ; Hab.—Throughout India. The herb and root. Vernacular.—Sént, Thikrt (Hind. ), Purna, Punarnaba (B Khipra, Punanava, Kélivasu, Ghetuli (Mar.), Mékku- (Tam.), Atika-m4 midi (Tel.), Vakha-khaparo, Sétod{ . (Guz.), Ganajali, Biléganjali (Can.). ae History, Uses, &c.—This plant is called by Sant medical writers Punar-naya, Punar-bhava, and Punar-bhu, account of its perennial habit, and Sothagni from its use a8 remedy for dropsy. It is described in the Nighantas as pun; dry, hot, swee diuretic, and stomachic in jaundice “nal inflammations, A compound de made of the roots, dried Neem bark, leaves of Trichosanthes dioica, dried ginger, root of Picrorhiza Kurrooa, chebulic myrobs stem of Tinospora cordifolia, and dried wood é (Dérhalad), each one quarter tola, water 32 tolas, NYOTAGINE AI. - Fi down to one-fourth, which is to be taken during the 24 hours, An oil and electuary are also used. Ainslie mentions the use of the root in powdelya in the quantity of a teaspoonful twice daily, as a laxative. In the Pharmacopeia of India its successful use as an expectorant in asthma is noticed, and it is said to act as an emetic when given’ in large doses, This has been confirmed by the experience of the _ French in the Antilles, where the plant is called Patagon or _ Patagonelle-Valeriane. In Western India the herb is used as a _ diuretic in gonorrhea, and as an external application the pounded leaves are applied to dropsical swellings. In the rainy season, when luxuriant, it is eaten as a potherb, after having been well boiled to remove its medicinal properties. The use of the root in gonorrhea appears to have been introduced by the Portuguese ; in the West Indies the plant is known as Bejuco _ de purgacion, and is the popular remedy for that disease. A _ decoction (1 oz. to a pint of water) is used in doses of a _ wineglassful every hour. a oe _ Description.—A common creeping weed on waste ground : and roadsides ; stalks numerous, about two feet long, slender, _ procumbent; leaves cordate-ovate, unequal, opposite, ed, _ waved, tinged with red ; flowers small, sessile on the apex of the pedicels, peduncles Scan the axils and ends of the branches; fruit _ oblong, dull green, or brownish, viscid, about the size of a _ caraway, longitudinally 5-grooved, studded all over with glan- q dular hairs ; root twisted, often as thick as the finger when q fresh, whitish, fleshy, 2 to 3-branched, a foot long or more; 3 taste bitterish, nauseous. A microscopic section shows that _ the parenchyme is loaded with needle-shaped crystals, other- : _Wise there is nothing peculiar. _ There are two varieties of the plant, one with white and the other with red flowers; in Bengal the former is called Svetapurna and the latter Gudha-purna. 4 Chemical composition—The whole plant was used for the : examination, and, with the exception of minute traces of a nciple soluble in ether, and affording reactions - with " 182 NYOTAGINES, alkaloidal reagents, nothing of interest was detected. Ni principle reacting with ferric salts was present. MIRABILIS JALAPA, Linn. Fig.— Bot. Mag., t. 871 ; Rheede, Hort. Mal.w., t. 75. Mi vel of Peru (£ing.), Belle de nuit (Fr.). Hab.—West Indies. Cultivated in India. The | and root. © Vernacular.—Gul A’bbas (Pers., Ind.), Krishna: keli (B Anthinarlu, Patharachi (Zum.), Batharachi (2 Madhyénhamallige (Can.), Antimalari (Mal.), Gulbés, Gu: -(Mar.). . History, Uses, &c.—Five varieties of this pla red, white, yellow, red and white, and red and yellow were introduced from the West Indies in 1596, and must been carried by the Portuguese to the East shortly a as the plant is said to have been introduced into Persia reign of Shah Abbas the first, and was established Malabar Coast in the time of Van Rheede. It was at supposed to produce the Jalap of commerce. UM. J been given the Sanskrit name of Sandhyakali, or re but is best known by its Persian name of G “flower of A’bbés” ; it is a favorite flower of the Per “belle de nuit”; it is the Fula quadrohoras, or * four flower,” of the = eae: as its flowers open at in the afternoo In India the — boiled in water are applied as oat u boils and buboes, and the j juice, which is considered to cooling, is applied to the body to allay the heat and itching urticaria arising sage Sere cutee the U. seit T.ab ti by bilaie: 18 : NYCTAGINE. 133) but Loureiro remarks, ‘‘ Hee radix non est apta ad medicinam, 4 nisi per aliquot annos in viva planta senescat ; tuncque sit subro- 2 tunda, rugosa, exterius subnigra, intus fusco-pallida, circulis. _ concentricis nigricantibus distincta.’’ In the Goncan the dried 3 root powdered, and fried in ghi with spices, is given with milk asa paushtik or strengthening medicine, and rubbed down with _‘ water to a paste it is applied to contusions, the same quantity of root with 24 drachms each of nutme > mace, and Atis root, ghi 1 oz., sugar and milk of each 10 ounces, Dose as above. Dr. Mootooswamy finds the root to act as an astringent in these preparations. Ainslie, quoting Fleming (Cat., p. 29), states that the root was tried as a purgative by Drs. Hunter and _ Shoolbred, but found to have so feeble a purgative action as to _ be useless. He also tried it himself with the same result. _ _ According to Thunberg, the Japanese prepare a kind of white _ paint for their complexions from the seeds, __ ee _ _Description.—The root of young plants is cylindrical above and tapering below, but in old plants it becomes napiform or subrotund, the external surface is dark brown and marked with numerous circular rings; internally it is dirty white or greyish. When dry, very old roots become hard, compact and heavy, and deepen in colour, but younger roots are of a lea consistence. It has a faintly nauseous odour, and a sweetish, subacrid taste. A transverse section of the root shows numer-~ ous concentric rings of a darker colour than the intervening substance ; it shows numerous acicular crystals when magnified, Chemical composition.—The roots were collected in into slices, and exposed to warm air, then d the desiccation completed at 100° (, FR eR Ta a ae wees ee ere rene thery reduced to powder July, cut 134 NYCTAGINEZ. - The fresh roots dried over sulphuric acid lost 81°136 per cent. in weight; the ash amounted to 6-135 per cent., and was free from manganese. The proximate analysis was made with the powdered roo dried at 100° C., and was conducted according to Dragendorfi’s plan with the following results :— Light petroleum ether extract 0-580 per cei Ether extract, soluble in water 0:09 per cent. alcohol 0-222 Residue insoluble in water or alcohol sows 0028. 5, OBA ae Absolute alcohol extract ......... 3040 ,, Aqueous extract containing glucose 1-6 per cent., saccharose or allied carbohydrate #o0 per cent. i.icis.. 30°62 a) The petroleum ether extractive was soft and pale yellor in colour, non-crystalline, and without any special odour. consisted of wax, anda pale yellow oil, soluble in absolute alco with neutral reaction. : The ethereal extract was soft and yellowish. The portic soluble in water had an acid reaction, but gave no colora with ferric chloride. Acidulated with sulphuric acid a slig! precipitate was afforded with Mayer’s reagent. The residue the ethereal extract soluble in alcohol was also yellowish, | | on standing became indistinctly crystalline. Treated reactions; with alkalies on gently warming it was slight soluble, with pale yellow coloration : the colour being destroy} wi i aa he AMARANTACEM. 435. ve js eet | ) amounted to 0°384 per cent. and contained a small amount of alkaloid with much colouring matter. An attempt was made to purify the alkaloid by reagitating this extract from an acid solution with ether, and then neutralizing and again agitating with ether ; an unweighable amount of the alkaloid was, however, obtained. No special colour reactions of the alkaloid were noted. An alkaline solution of the alcoholic extract was only slightly precipitated by acids, the solution remaining dark- _ coloured. e aqueous extract contained 1°6 per cent. of _ glucose calculated on the roots dried at 100°C. After boiling _ with dilute sulphuric acid a second determination with Fehling’s solution was made, and the result calculated as saccharose, which was equivalent to 7°97 per cent. SARS tee er ers In order to determine whether the plant had any injurious properties, the alcoholic extract from 10 grams of the dried and pounded roots was mixed with a few drops of ammonia and water and injected into a cat’s stomach; the cat vomited once, but was not otherwise inconvenienced. AMARANTACEA. ACHYRANTHES ASPERA, Linn. Fig.— Wight Ic., ¢. 1780. Prickly Chaff-flower (Eng.). Hab.—Throughout India and tropical Asia. The herb. _ -Vernacular.—Unga, Latchira, Chirchira (Aind.), Apang _ (Beng.)., Pandhara-4ghada, Aghada (Mar.), Sufed-4ghado _ ( Guz.), Na-yurivi (Tam.), Uttareni, Antisha (Te/.), Uttaréni, ’ Uttaréni (Can.), Katalaéti (Ma/.). History, Uses, &c.—This plant has given a name to the sacrificial offering called Apamarga Homa, which consisted of a handful of the flour of the seeds offered at daybreak, but which is not now, as far as we know, practised in India. According to the Black Yajurveda, Indra, having killed Vritra and other emons, was overcome by Namuchi and made peace with him, romising never to kill him with any solid or liquid, neither by nor by night. But Indra collected some foam, which is = = The ashes with honey are given to relieve cough; the root y doses of one told is given at bedtime for night blindness, am 136 AMARANTACEZ. neither solid nor liquid, and killed Namuchi in the mornin between night and daybreak. From the head of the demon sprung the herb Apamarga, with the assistance of which Indr was able tokillalldemons. Hence this plant has the reputati of being a powerful talisman, and is now popularly suppose day of the Divali (new year) festival. The Sanskrit synonyms for the plant are Shikhari, Kini Kinihi, Khara-manjari “having a rough flower-stalk,” Adh shalya “roadside rice,” Shateliorties: Pratyak- -pushpi “havin reverted flowers,” and Mayuraka “crested.” It is described it the Nighantas as purgative, pungent, digestive; a remedy 10 Bidcom. wind, inflammation of the internal organs, piles, iteh abdominal enlargements, and enlarged cervical glands. ashes are used by the Hindus in preparing caustic alkaline pre parations. The diuretic properties of the plant are well kno to the natives of India, and European physicians agree as to value in dropsical affections; one ounce of the plant may be bout ed in ten ounces of water for 15 minutes, and from 1 to 2 ow of the decoction be given 3 times a day. (Pharm. of Ti : p- 184.) Different parts of the plant are ingredients in many native prescriptions in combination with more active remedies. In Western India the j juice is applied to relieve toothac Tec: rubbed i into a paste with water it is used as an anjan (eye salve, in opacities of the cornea. The seeds are often used as a famine food in India, especially in pigeteos, where the plant is called Bharotha, wat (er ass). nee =e common weed, with 4 an erect, striated pubescent stem, generally about two feet high, but sometimes muchmore. Sid de branches in ie ree leaves antes : * Count with Serioaies Seow i 1 sy ) are reco -AMARANTACEA. -. io¢ 3 from the presence of a thick coat of long simple hairs, obovate, undulated, very obtuse, acuminated, base attenuated ; petiole _ short ; spikes long, lax ; flowers green; bracts rigid, prickly. Sections of the stem do not show any crystalline deposit in _ the parenchyma. The seeds are oblong, of a brown colour, from ,5, to $ of an inch in length; on one side a grooved prominence is séen which indicates the position of the embryo _ where it curves round the mealy albumen. The starch granules e very small, and areso closely packed that the large irregular- aped cells which contain them have almost the appearance of parenchymatous cells. Chemical composition.—The whole plant collected in August _ wasused. A proximate analysis failed to indicate the presence ' of any principle of special interest. No alkaloidal body was detected, and the alcoholic extract contained no principle reacting _ with ferric salts. For the ash determination, the roots, stems and leaves were separately examined with the following results:— | Leaves. Stems. Roots. ede ears es 3°0257 2°6939 1°8594 o* as fend 39°7192 12-9716 21°4219 wiv os 00 2°653 BU) cangiven sot 13°8893 13-1233 12°9335 oeevie 3°4778 3°5149 4419 17°8454 32-0008 28:5830 Wied). ae PEER tas ‘9860 See beecws sae 2°7931 3°0352 5 6297 eine, Traces, not jNot estimated. | Not estimated. estimated : 57 4) 2s rer ee 11770 15261 3-2951 socvay caus i 2°0651 |Not estimated. |Not estimated. 8-8687 13-629 110057 sapien "3297 ‘5525 \Not estimated. 100-2526 95-2232 95:1085 IlL—18 138 AMARANTACE. The leaves, stems, and roots dried at100°C. afforded respectiv aly the following percentages of ash :—Leaves, 24'334 ; stems, 8°672 ; : roots, 8°863. The large amount of sand present in the ash is due to the fact of the plants having been collected during the rains, and when received they were coated with finely divided silicious matter, The total potash calculated as K*O was equivalent in the leaves to 21:4986 per cent., in the stems to 38-0122 per cent., and m the roots to 28-5830 per cent. It is possible that the plant ~ might be of yalue as a cheap green manure on account of its potash content. (Warden, Chem. News, Vol. ii., 1891). Amarantus spinosus, Linn., Willd. Amar. 38, t.4,f.83 Vern.—Tanduliya (Sans.), Kaénteméth (Bomb.), Kéntanatia (Beng.), Mulluk-kirai(Tam.), Kéntélo-dambho ( Guz.), possesses mucilaginous properties. The Hindu ph ysicians prescribe the root in combination with other drugs in menorrhagia. It is considered to be a specific for selin. A poultice of the leaves was officinal in the Bengal Pharmacopeia. The authors of the pit ehe aoe of India regard the pla F 4ERUA JAVANICA, Juss. Fig.—Wigit Ic., t. 876. . Hab.—Plains of India. The herb, — ZERUA LANATA, Juss. Fig. —Wight Ic., t. 723; Rheede, Hort. Mal, w., t, 29. Hab.—Plains of India. The herb, : laser nt nee Beng.), Bhui-kallén (Puvj-); - _Kumra-pindi, teres sp naper phi (Mar, ), Pindiconda, _ Kamiupulai, Ni Nilapulai (7% ; ru Sirru-pulai (Pole AMARANTACEZ.. 139 History, Uses, &c.—These plants ave used by the 4 natives of India as diuretics, and are considered to be of great value in lithiasis; they are also thought to be antidotal in cases _ of poisoning by arsenic. ‘The flowers are sold in the bazars of _ Northern India under the name of Bhui-kall4n. 42. Janata is the Scherubala of Rheede, and Ainslie states that the Vytians consider the root to be demulcent and prescribe a decoction 3 in strangury; in the Concan it is used as a diuretic. _Z. java- nica has a great reputation in Hyderabad, Deccan, as a reme for lithiasis, and the flowers have been brought to us for iden- tification by the medical attendant of a gentleman in Bombay, who had been in the habit of obtaining them from Hyderabad under the Marathi name of Kumra-pindi, which is equivalent to _ the Telingi Pindi-conda, and signifies ‘“ cock’s pinda”’; we ' use. These plants resemble Achyranthes aspera in their _ medicinal properties. The flowers are very soft and woolly, and are used for stuffing pillows and mattresses in Sind and in _ Egypt. In Southern India the natives use the flowering 4 spikes during the Pongul festival for decorating their houses. ; Description.—The plants have a white tomentose appear- _ ance. The leaves are alternate. The minute flowers are in _ dense terminal or axillary spikes, those of 2. javanica being _ much the largest, often 4 to 5 inches in length ; they are herma- q phrodite, with three concave persistent bracts. The calyx q stamens are united into a cup at their base; the Ovary is one- 3 celled, with a single ovyule in each cell. The fruit is.a roundish 4 utricle, { CELOSIA ARGENTEA, Linn. Fig.— Wight Ic., t. 1767 ; Rheede, Hort. Mal. 2, t. 38, 30; Hab.—Throughout India and tropical Asia. The seeds. Vernaculay.—Sarwali, Suféd-murgha (H ind.), Svet- eng.), Lapadi (Guz.), Kurdu (Mar.), Gurugu (Zel.), Gor, Can.) saat with an equal quantity of sugar-candy, taken, daily in a the French, and Wasserampfer of the Germans. ea 140 AMARANTACEZL. History, Uses, &c,—This common annual plant is con- — sidered by some to be the Vitunna of Sanskrit writers ; wh young and tender it is eaten as a vegetable, but is considered t be very heating. The seeds are considered an efficaci remedy in diarrhea. Indian Mahometan writers on Mate Medica have adopted Sarwéli as a substitute for the Aperavey ¢ Dioscorides, and the Herba Britannica of Pliny, which has b identified by Prof. Muntingius of Groningen as Rumer Hy¢ lapathum, Huds., our Water Dock, the Patience aquatique ( of the Muffaridat-i-Nasiri states that 180 grains of the milk, is a most powerful aphrodisiac. Dr. Watt (Dict. Econ. Prod. Ind.,ii, 240) states, on the antih of the Rev. A. Campbell, that the Santals extract a medici from the seeds. - Description.—Stem 1 to 3 feet, stout or dcndaes sim branched ; leaves 1 to 6 inches, narrow ; spikes soli many, | to 8 by } to 1 inch; : pidanals slender ; flows w tipped with pink, glistening; bracts much shorter than thes sepals. Seeds lenticular, brown, ‘polished, ~; of an im “a diameter. : Chemical composition.— The following is an analysis Snel powdered seeds :— ; On re - Resin, soluble in ether .........02........ ‘81 Alocoholid-oxtract —....cwaiieie a 198 WRF GRUNER sires ccccinitc .. 24°70 Miah, See Sosehs coven EO BUDE eveswnciy sate cend doce osteherspg cay. A hae Ash ‘ 3 | Moisture cgi Sehgal delat he Mek SRY Se PT i me 10°80 r CHENOPODIACEE 141 The alcoholic extract contained an alkaloidal- principle precipitable by alkalies, soluble in ether, and giving a rose colour with strong sulphuric acid. CHENOPODIACE. USHNAN. Genera.—Arthrocnemum, Caroxylon, Salicornia, Salsola, Suzeda, Soda plants. History, Uses, &c.—Sarjikakshara has doubtless been prepared in India, as it is at the present time, from avery early date. In the time of Pliny a mineral alkali appears to have been prepared in Egypt from the ashes of certain plants and to have been known as Natrum, or in Greek vitpov (Plin. 31, 10), and Strabo, as cited by Beckman, mentions an alkaline water in Armenia used for washing clothes. (Hist. of Invent. iii., p. 233,) The plants from which Barilla was prepared were known to the Greeks as 7¢ dAwoy or salt-worts. (Theophr. H. P. iv., 20 ; Diosc.i.,105.) The Arabsalso were early inted with | the same substance, which seemsto have been sometimes potash, or a mixture of soda and potash in various proportions, and to which they gave the name of «J! El-kali or alkali. The Arabian writers describe Ushnén as good for the mange or scab, and the itch; clearing to the complexion, cleansing, emmenagogue and abortive, and a substance with which clothes and the hands are washed. The author of the Makhzan, speaking of Ushndén, states that it is a name applied to several plants, one of which has slender branches instead of leaves, upon which knob-like bodies form (Sueda fruticosa?). _ This plant is always fresh and j juicy, and isa large herb with q round woody stems. He then describes the manner in which : : 4 Bee te, pea So other plant with reddish stems and leaves three deep, at the bottom of which one or more inverted earthem 142 CHENOPODIACEZ. ‘i side and green on the other (Chenopodium atriplicis ?), yielding & juice which stains black ; this plant he says is very common — in Sind and Miltan, and is used for staining the black pattern on the Sind pottery. Lastly, he mentions a plant called Khuri- el-’asafir (sparrow’s dung) with white leaves (Chenopodium album ?), and another which is called in Persia Ghasool, and gives the following list of plants which are used in the manu- facture of Sajji-khar or Barilla :— Arthrocnemum indicum, Mov. Caroxylon foetidum, Moy. ar Griffithii, Moq. Salicornia brachiata, Roxb. Salsola Kali, Wild. Sueeda fruticosa, Forsk. 99 indica, Moq. - nudiflora, Mog. ; Aitchison states that the name Ishlan (probably a mispronun= ciation of Ushnén) is applied in the Hari-rud Valley to Anabasts erispoda, Benth. et Hook. f., which is used in preparing barilla. In the Report on Punjab Products, it is stated that the plants oS are cut down during the cold months, dried and burnt in @ pit of a hemispherical shape, about six feet in circumference pots, having small holes in their bottoms, are sunk. Th holes are kept closed at first, but when the alkali begins to run, they are cleared to allow it to fill the pots ; when cool it forms 4 porous mass of a greyish-white colour, consisting of carbonates” of soda and potash, sulphate of soda, and organic matter. : native practice this substance is prescribed like our preparations — of the caustic alkalies. It is the Sarjikékshdra of the Raja _ Nirghanta and the Saji of the bazars, | ee CHENOPODIACE&. 143 SHUKAIT. Hab.—Persia. The herb. Vernacular.—Shukai Und. Bazars). History, Uses, &c.—This drug is described in Maho- metan works as the Akran‘k(* or Afsharniki of the Greeks. _ Other Arabic names given are Shaukat-el-baida, Shaukat-el- _ Arabiya, and Kathir-el-rakab. Ibn Sina says it is the same as Baézaward (Bédaward, Pers.) Muhammad Husain very truly denies this; he says the Persian names are Charchah and Kangarkhér, and describes two varieties, one with a white flower and more slender stems than the other, which has purple flowers, and is the kind generally used. The latter, he says, has triangular stems, the size of a man’s finger or less, and thick, small, triangular, downy leaves terminating in thorns; the seeds are small, triangular, and of a greyish colour. The whole drag is of a yellowish white colour and sweetish taste. The plant _ and fruit are generally used, but the root is to be preferred. Shukai is more drying and astringent than Bédaward; it is _ attenuant and deobstruent, &c., &c. (Makhzan-el-Adwiya, article Shukai) Haji Zein-cl-Attar states that it is useful in _ palsy and other diseases caused by cold humors. He quotes Galen as recommending its use in melancholia, and Paulus as _ saying that it is useful in leprosy. In Persia it is said to have areputation as a remedy for ague. The dose is from 2 to 5 _ dirhams. 4 Description.—The drug as met with in India consists of all parts of the plant broken up, but very little of the root is present. The portions of the stem are of a greenish-yellow colour, round, crooked, channelled, with numerous branches springing from the axils of the leaves ; the external surface of the stem is siliceous, hard, and pubescent; internally it is full of soft pith. The petioles of the leaves are stem-clasping, the lower ones completely so. The lower leaves are of considerable ree ee Nee ar Ie ee eMe Hen Tee . aE ty eee = terminates in a thorn. Possibly from dxpévuxos, on account of its thick leaves, each — of aS 144 CHENOPODIACE Ai. size with a triangular midrib, channelled on the upper surface, and short, thick, spinous lobes which vary much in shape. The plant has a gummy, rather disagreeable taste. The fruit is occasionally found mixed with the drug in considerable quan- tity. It is a woody nut, } of an inch long, formed by the fusing together of the different parts of the perianth and ovary, somewhat triangular in form; at the base are spines formed by the calycine segments; at the apex the perianth forms a number of tooth-like processes which surround the top of the ovary: The seed is ovoid, horny, and has a terebinthinate odour. Chemical composition—The chopped plant, air-dried, was treated for several days with warm 80 per cent. spirit, the resulting tincture distilled to remove alcohol, and the residue finally deprived of the last traces of alcohol by spontaneous eva poration. The extract. was then mixed with water acidulated with sulphuric acid and agitated with petroleum ether. other alkaloidal reagents. ed of a bright yellow hue; basic acetate of lead gave a bright yellow precipitate, a similar precipitate, but smaller in amount, : being also afforded by lead acetate. The soft resinous residue ee ‘insoluble i in proof spirit, after standing deposited a smal] amount of bright yellow matter which was destitute of crystalline structure on microscopic examination. In ammonia the ac was insoluble. During agitation of the extract with petroleum ether a consi- derable amount of dark, soft resin separated ; this resin had @ marked peppermint odour, and was only partly soluble in ether- After repeated washing with ether, it was left as a dark, soft mass which could be kneaded by the fingers; on drying at 100°C. a nearly black brittle mass B wanlalt, easily pul ace Merny ee ee Serene ere ee CHENOPODIACEE. —=————«‘4.45 and forming a dark olive-brown coloured powder, odourless and tasteless, but bitter in an alcoholic solution, soluble in ammonia, forming a deep yellowish brown solution, from which it was reprecipitated by acids in dirty yellowish white flocks. In alcohol the resin was easily soluble with acid reaction; with ferric chloride the alcoholic solution was slightly darkened in tint, After agitation with petroleum ether the acid aqueous solution was agitated with ether: the ether extract was small in quantity, and though some small points separated on the sides of the dish which appeared crystalline on naked-eye inspection, on micros- copic examination no crystalline forms were visible. In water the extract was partly soluble with strong acid reaction : the aqueous solution gave with ferric chloride a dirty bluish-green precipitate, changing almost instantly to dirty whitish-brown. With alkalies a bright yellow coloration was afforded; the solution did not precipitate gelatine and gave no reaction with cyanide of potassium. The ether extract was treated with ammonia, in which, with the exception of some flocks, it appeared to be wholly soluble. The solution exhibited a marked greenish fluorescence; it was agitated with ether. The ether extractive formed a non-crystalline yellow varnish, soluble in alcohol without fluorescence, with a very bitter taste and neutral reaction; treated with dilute sulphuric acid a small portion dis- solved, and the solution afforded marked reactions with all alka- loidal reagents. The alkaline aqueous solution was acidulated, which caused whitish flocks to separate, and agitated with ether. The ether extract was a non-erystalline yellow varnish, partly soluble in water with strong acid reaction, the solution affording similar reactions to the original sortie solution of the ether ex- tract. Th solution exhibited a greenish fluorescence. The original aqueous acid solution was now rendered alkaline and reagitated with ether; a yellow varnish was obtained after spontaneous evaporation of the ether. The extract was treated with dilute sulphuric acid and agitated with ether, the ether separated, the aqueous solution rendered alkaline, anda a agitated with ether, in order to purify any alkaloidal princi ple oe 1IL—19 146 CHENOPODIACEZ. which might be present. The purified ether extract dried toa E yellow varnish; the solution in sulphuric acid gave a very marked yellowish precipitate with: Mayer’s reagent; a white precipitate with alkalies; with Fréhde’s reagent, a precipitate: first yellowish, rapidly changing to pale blue, and darkening, on standing or warming, to deep prussian blue; chromate of potash gave a yellow precipitate; bichromate of potash and concentrated sulphuric acid, a dirty orange-red ; ferric chloride no reaction; the solution was destitute of any bitter taste. Considerable loss of alkaloid occurred during its purification, the sulphate was somewhat soluble in ether. Finally the original alkaline aqueous solution was acidulated with sulphuric acid, and agitated with amylic alcohol. On evaporating off the amylic alcohol, a deep orange-red varnish was left, partly soluble in water with strong acid reaction, the solution giving an olive-brown coloration with ferric ‘chloride; no precipitate with gelatine; a bright yellow coloration with alkalies ; a bright yellow precipitate with basic acetate of lead and it reduced Fehling’s solution on boiling. The residu insoluble in water, was dissolved by ammonia, forming a deep orange-yellow solution from which acids afforded a whi precipitate, the yellow colour being destroyed, SPINACIA OLERACEA, Linn. _ Fig.—Lamk. Encycl., t. 814; Wight Iv., t. 818. Spinach _ (4ng.), Epinard (F+.). Syn. S. tetrandra, Stev. : ‘ ~Hab.—Persia. Cultivated in India. The herb and fruit. _ Vernacular.—Palak ( Hind.), Palang (Beng.), Vusayley-keeray (Tam). 7 : History, Uses, &c.—This potherb is a native of Persia; it is described in the Persian Burhén under the name of chee (ispanékh) as a potherb much used in broth. The name is now often incorrectly pronounced Ispand, ians, and Isfai.dj or Isfénaj by the Arabs. The plant has been int into India by the Mahometans, and is now cultivated in mam: CHENOPODIACEA. 147 parts of the country. The African Moors brought it to Spain, whence its use gradually spread to other parts of Europe. It was known in England as Spinach in 1568, and is noticed in Turner’s Herbal, published in that year, as “lately introduced and not much in use.” Aitchison, in his Botany of the Afghan Delimitation Commission, remarks that it grows profusely in the vicinity of Simkoh in the Badghis, and is collected as a potherb by the natives. He says:—‘‘I have no doubt Mr. De Candolle is correct in assuming QV. tetrandra to be the wild form of S. oleracea.” Spinach is much valued by the Mahometans on account of its cooling and emollient properties, and the seeds are sold in all the Indian bazars, A decoction of the plant is prescribed in febrile affections, in lithiasis, and in inflammation of the lungs or bowels. The juice of the leaves is also used asa _ diuretic and as a gargle in sore-throat. Poultices of the leaves ___ or boiled seeds are applied to soften tumours and promote the maturation of boils. The herb is considered one of the most digestible and wholesome of vegetables. Het SORES ere See c Description.—The plant has large, thick, succulent, deep- green leaves, of a somewhat triangular form, produced on long foot stalks. The stem is erect, large, round and hollow, about _ two feet high. The male plants are distinguished by their long _ terminal spikes of green flowers, while those of the females are axillary, sessile and clustered. The fruit is prickly in some varieties and smooth in others. Chemical composition.—Besides a large quantity of mucilage spinach contains so large a proportion of nitrates, that the water in which it has been boiled may be used for making touch- paper. The following figures give the mean percentage com- ‘position of three samples of spinach recorded by Kénig :— ter 88°47 Nitrogenous matter a. Sa Fat ‘ 0°58 Sugar 0°10 Nitrogen-free extractive ...........s06. 4°34 Fibre 0-93 Ash . Oa 148 © POLYGONACEZ. Anhydrous spinach contained, as the mean of three analyses of different samples,— : Nitrogen 4°94 Carbohydrat 37°93 Basella alba, Linn., Wight Ic., t. 896, is known as Indi spinach, or Malabar Nightshade, and the juice of the lea : which is demulcent and cooling, is a popular application — allay the heat and itching of urticaria arising from dyspep : an affection which the Hindus consider to be indicative of in the blood. The boiled leaves are also used as a poul This herb is extensively cultivated as a vegetable, and bears vernacular names of Poi (Hind.), Maydl (Mar.), Vasala - Bachchali (7el.), and Bili-basale (Can.). The generic n derived from the Tamil. The Sanskrit name is Potaki or Upodil Many plants of this order are used as potherbs in the East. Persia and Biluchistan, Chenopodium Botrys, Linn., ( Blitum, Hook. 7., and Atriplex Moneta, Bunge, are used. On the Indian coasts, Arthocnemum indicum a plant of the salt marshes, is used as a vegetable, and — pickled. Fryer, who visited Bombay in 1694, calls it “samphi Plants more generally known as vegetables are Cheno dium album, Linn., C. ambrosioides, Linn., E vulgaris, Iénn., and Atriplex hortensis, Lian. Th of the Beet are sold in Indian Bazars for medicinal use, - the-name of Chukandar. — - POLYGONACEA, _POLYGONUM AVICULARE, Linn. Fig.—Eng.. Bot., 1252, Knot-grass (Eng.), Renouée oiseaux (Fr.), ~ Hab.—Northern The root and seeds. Vernacular.—Machoti, Bijband, Kesri (Hind Asia, Europe. Introduced into ). per ee POLYGONACEZ:. 149 History, Uses, &c.—This plantis identified by Fée with the male modtyovey of Dioscorides, a vulnerary and astringent herb, the Polygonos of Pliny (27, 91). It was used by the ancients to arrest hemorrhage, the seeds were considered to be 3 laxative and diuretic and to arrest defluxions. For burning _ pains in the stomach the leaves were applied topically, and were used in the form of a liniment for pains in the bladder and for erysipelas. The juice was administered in fevers, _ tertian and quartan more particularly, in doses of two eyathi, just before the paroxysms. Scribonius (Comp. 46) says that it received its name ‘“ polygonos” from its being found everywhere. Ibn Sina and other Arabian physicians call the plant A’sa’r-ra’i-(cse lJ !Las) and Batbat (£45:); they consider it to be cold and dry, and reproduce what the Greeks _ have said concerning its medicinal uses. The Persians call _ it Hazar-bandak. It is the Polygonum mas of Matthiolus | {Vaigr. ii., 800). In India the plant is still used by the Hakims in the diseases _ named by Dioscorides. _ __ _Inour own times Polygonum root has-been used asa tebrituge _ in Algeria, and has been reported upon as being an excellent © _ remedy for chronic diarrhoea and stone in the bladder. Its _ value has apparently been much exaggerated. (J. RF. Jackson, _ Amer. Journ. Pharm., 1873, 247.) In the Lancet (1885, 658) it is said to be used in ee 4 under the name of Homeriana, as a popular remedy in lung _ affections. Dr. Rotschinin, who has experimented with the _ drug, found it really valuable in several cases of bronchitis, two = of which were capillary; also in three cases of whooping cough. It was tried in phthisis, but no definitely satisfactory results were obtained. A tumblerful of the decoction was given three times a day. Description,.—Root fibrous, long, very tough, and some- hat woody; branched below, simple at the crown. Stems veral, spreading in every direction, generally prostrate, much nee Oa 150 POLYGONACE. branched, round, striated, leafy at the numerous knots or joints. 4 Leaves alternate, stalked, hardly an inch long, elliptic | lanceolate, entire, obtuse, single-ribbed, smooth except at t rather cori ,colour greyishor glaucous. Flowers variegated with white, crimson and green. Seeds acutely triangular, of shining black. Polygonum Bistorta, Linn., is the Anjubar of the Western Arabs, and their description of it is still reproduced in - Indian medical works. P, viviparum, Linn. a nearly allied species, is used as a substitute for it in the Punjab, under the same Arabic name, and is called in the vernacular Maslun ané Bilauri. The Anjubar-i-Rumiof the bazars, imported from Persia, is a thick reddish-brown astringent root-bark, evidently obtained from a tree or shrub of some size, and it may. observed that Aitchison found an arboreous species of Polygonum growing in the Badghis and Paropamisus. | Other species of Polygonum which have been used medicin~ ally, and which occur in India, are:— P. glabrum, Wilid., P. Hydropiper, Linn., P. molle, Don., P. barbatum, Linn., and P, alatum, Ham, All these plants are astringent, but P. Hydropiper also contains a pangen volatile principle having acrid properties. -Chemical composition—Dr. ©. J. Rademaker (Amer. Journ: Pharm., Nov. . 1879) separated from P. Hydropiper a a : bat . Trim the plant with the following results:—They found that = peculiar pungent principle, although present in a alcoholic tincture, disa sappeared on distillation, the pungent taste of the herb being absent both from the distillate and the residue in the reto: From these experiments they conclude that the active prit- ciple is decomposed on ee eaing: and that the only POLYGONACEX. 151 q proper preparation of the drug would be one made without the application of heat. They prepared the polygonic acid of Dr. Rademaker, and conclude from their experiments that it is only a mixture of impure tannic and gallic acids, The following summary shows the amount of the most impor- tant constituents :— _ 4 : Per cent. a petroleum spirit — solution. _ Resin and chlorophyll ......... 154 From ether solution. Resin, tannin, andchlorophyll. 5-14 From alcoholic solution. i 1:44 *55 & From aqueous solution. 00 } From alkaline solution. 57°45 97°25 parately determined : tannin, 3°46 per cent. ; ash, 7°40 per cent. ear-Book of Pharm., 1885, p. 160.) Dr. C. J. Rademaker (Amer. Journ. Pharm., June 1886) asserted the existence in this plant of the active crystalline rinciple, described by him as polygonic acid, and supplied further details respecting its extraction and properties, together th a wood-cut illustration of its crystals. Hesays:— “ Poly- owing it to macerate for 24 hours; or by precipitating 152 POLYGONACE. a fluid extract with basic acetate of lead. In each case separate the base by means of sulphuric acid, and the organic acid b means of ether. Allow the ethereal solution to evaporate, treat the residue with distilled water, and filter; this sepa the resin (resinous acid). The filtrate is then filtered thro animal charcoal repeatedly, until all colouring matter is remo The filtrate is next treated with solution of gelatine, in order ' remove any tannic acid that might be present, again filte and evaporated to dryness, redissolved in ether, and the ethere: solution allowed to evaporate spontaneously. Polygonie act thus prepared crystallizes in needles, Its solution in wate: not precipitate gelatine nor produce a bluish- -green colora when added to a mixture of ferrous and ferric salts in so. showing absence both of gallic and tannic acids. It is soluble in water, less so in ether, and insoluble in pe spirit. The heat of a water-bath does not destroy any properties. ( Year-Book of Pharm., 1886, p.210.) - The other species of Polygonum which have been ex# contain starch and tannic and gallic acids. Bowman obtained 21 per cent. of tannic acid from Bistort root. In Bengal Chemical Examiner’s Report for 1884 we meet wit following notice of P. glabrum : “ Several specimens of @ called Bish-kurki were sent from Cachar for examination. was stated that the plant was frequently added to ¢ : spirit, which it was believed might have thus communicated! it some specially noxious property. The plant was iden by Dr. G. King as Polygonum glabrum, and on chemical nation and oe application was not found to | ~ toxic — ‘RHEUM OFFICINALE, Baillon. lg —Bentl. and Trim., t. 213. Rhubarb (Eng), 3 barbe (Fr.). . Hab, South-Basor Witt, Chinn _ The a oa POLYGONACEA.. 153 RHEUM PALMATUM, Linn. | Fig.—-Bentl. and Trim., t. 214. Rhubarb (E£ng.), Rhu- ___ barbe (F.). | Hab.—South-Eastern Tibet, China. The root. Vernacular.—Rewand-chini, Lakri-rewand-chini(Znd. Bazars). History, Uses, &c.—The Chinese appear to have been acquainted with the properties of rhubarb from a period long anterior to the Christian era, for the drug is treated of in the herbal called Pen-king, which is attributed to the Emperor Shen-nung, the father of Chinese agriculture and medicine, who reigned about 2700 B.C. The drug is named there Huang-hing, _ yellow, excellent, and Ta-huung, the great yellow. The latter name also occurs in the great Geography of China, where it is stated that rhubarb was a tribute of the province Si-ning-fu, eastward of Lake Kuku Nor, from about the 7th to the 10th _ centuries of our era. As regards Western Asia and Europe, we find a root called pa or fnov, mentioned by Dioscorides as brought from beyon _ the Bosphorus. Pliny describes a root pee & Rhacoma, which, _ when pounded, yielded a colour like that of wine, but inclining _ to saffron, and was brought from beyond Pontus. The drug _ thus described is usually regarded as rhubarb, or at least as the _ root of some species of Rheum. Lassen has shown that trading ™ caravans from Shensi in Northern China arrived at Bokhara as 2 early as the year 114 B.C. (Pharmacographia.) __ Riwas (the plant Ri in the Zend language) was known to the ancient Persians, and the same name is still applied to a species of Rheum in the province of Gilin in Persia. Aitchison found — f. Kibes, Gronov., on the Paropamisus range, to be known to the peasantry as Rewash, Rewand and Chukri; he states that the flowering branches are eaten, and the root used in colouring leather. Inthe Hari-rud Valley he found R. tataricum, Linn., £., to be known as Rewash-i-dewina, “ fools’ rhubar a the oh it and root being used as a purgative. Ibn! “sina ae 8) 11I.—20 Sas He : _ flowers are red, and have a slightly acid and sweetish taste. The 154 POLYGONACES, notices both the plant Ribiés (Riw&s, Pers.) and the drug q R4éwand (Rewand, Pers.) —the first an acid plant, and the second . evidently Chinese rhubarb. Mesue, early in the 11th century, distinguishes between Chinese and Khorasan rhubarb, and Haji Zein-el-attér, writing in 1368, says:—I consider Rewand to be the same as Ribdés. Ibn Jazla, the author of the Minhaj, states that there are two kinds, China and Khorasan rhubarb, and th the latter is known as R4wand-el-dawabb, and is used in vete 1- nary practice, whilst the Chinese is reserved for human beings. The latter is the best kind, and, when powdered, is of a saffron colour; the fractured surface has the grain of a cow’s hump, and is friable; it is called Rewand-i-lahmi (meaty rhubarb), and should be in large pieces like a horse’s hoof, and not»worm-eaten. In my experience there are three kinds of rhubarb—Chinese, Khorasan, and Indian. Masih (Mesue) states that rhubarb is hot in the third degree and dry in the first.” (Jkhtiarat, article Rdwand.) a The author of the Makhzan-el-Adwiya, himself a native of Khorasan, has the following account of Ribés:—‘ with 2 ee ae * aon = Aristolochias in a Discve ie ele Tenore, the Sang-pwan-hea of the Chinese growing wheat Pekia (Hance, Iuinn. Journ. Bot, xiii. (1872), 88), fi sured and de> scribed by Hanbury. "Beince Papert; 9 382) nda i PIPERACER. 167 pepper bears the same names with the addition or substitution of the adjective “ white.” History, Uses, &c.—The earliest travellers from the West who visited India, found the pepper vine in cultivationon the Malabar Coast. Theophrastus (H. P. ix., 22) mentionstwo kinds of pepper (térept or wémept) in the fourth century B. C., and _ Dioscorides (ii., 148) mentions «vxov rémepi, white pepper, Haxpév méemept, long pepper, and péAav mereps, black pepper. Pliny says:— “Tt is quite surprising that the use of pepper has come so much into fashion, seeing that in other substances which we use, it is sometimes their sweetness, and sometimes their appearance, — _ that has attracted our notice; whereas, pepper has nothing in it — __ that can plead as a recommendation to either fruit or berry, its only desirable quality being a certain pungency ; and yet it is for this that we import it all the way from India! Who was the first to make trial of it as an article of food ? and who, I _ wonder, was the man that was not content to prepare himself, by 4 hunger only, for the satisfying of a greedy appetite?” (12, 14.) In the Periplus of the Erythrean Sea, written about A.D. 64, it is stated that pepper is exported from Baraké, the shipping : _ place of Nelkunda. in which region, and there only, it grows in ee _ great quantity. These have been identified with places on the = _ Malabar Coast between Mangalore and Calicut. __ Long pepper and Black pepper are among the Indian spices _ on which the Romans levied duty at Alexandria about _ A.D.176. Cosmas Indicopleustes, a merchant, and in later life a monk, who wrote about A.D. 540, appears to have visited the Malabar Coast, or at all events had some information about the pepper- plant from an eye-witness. It is he who furnishes the first particulars about it, stating that it is a climbing plant, sticking close to high trees like a vine. Its native country he calls Male. The Arabian authors of the Middle Ages, as Ibn Khurdadbah (circa A.D. 869-885), Edrisi in the middle of the | 2th, and Ibn Batuta in the 14th century, furnished nearly similar accounts. . 168 PIPERACE. Among Europeans who described the pepper-plant with a Some exactness, one of the first was Benjamin of Tudela, who visited the Malabar Coast in A.D. 1166. Another was the — Catalan friar, Jordanus, about 1330 ; he described the plant as something like ivy, climbing trees and forming fruit, like that of the wild vine. “ This fruit,” he says, “is at first green, then, when it comes to maturity, black.”’ Nearly the same statements are repeated by Nicolo Conti, a Venetian, who, at the beginning of the 15th century, spent twenty-five years im the East. He observed the plant in Sumatra, and also described : it as resembling ivy. ( Pharmacographia.) j The high cost of pepper contributed to ineite the Portuguese to seek for a sea passage to India, and the trade in this spice continued to be a monopoly of the Crown of Portugal as late as the 18th century. It is worthy of remark that all the foreign names for black pepper are derived from Pippali, the Sanskrit name for long pepper, which leads one to suppose that the latter spice was the first kind of pepper known to the ancient Persians and Arabs, a particle of light or fire,” and appears to have been first applied to the aromatic berries known as Kakkola; diners d in the Nighantas as bitter, pungent, os — se and dry ; Synonyms for it are Valli-ja “creeper grown shana Tiksh na “pur : re : = oe reer pungent,’’ Ma black,’ &c, Tt is said to be useful in intermittent ee? ee , pens wVYOR, See PIPERACEA. 169 dyspepsia, cough, gonorrhea and flatulence, and to promote the secretion of bile. Together with long pepper and ginger it forms the much-used compound known as Trikatu, “the three acrids, ”’ or ‘‘ Ushana-chatu-rushana.” Externally, pepper is used as a rubefacient and stimulant of the skin. In obstinate intermittent fever and flatulent dyspepsia, the Hindus administer ___ white or black pepper in the following manner :—A tablespoon- ful is boiled overnight in one seer of water, until the water is reduced to one-fourth of its bulk, the decoction is allowed to cool during the night, and is taken in the morning. The pepper is then again boiled in the same manner and the decoction taken at night. This treatment is continued for seven successive days. A compound confection of pepper (Prénada gudika) is given as a remedy for piles ; it is made in the following manner :—Take of black pepper 82 tolas, ginger 24 tolas, long pepper 16 tolas, Piper chaba (chavya) 8 tolas, leaves of Tawus baceata (talisa) 8 tolas, flowers of Mesua ferrea (nagkesar) 4 tolas, long pepper root 16 tolas, cinnamon leaves and cinnamon one tola each, cardamoms and the root of Andropogon muricatus (usira) 2 tolas each, old treacle 240 tolas; rub them together. Dose about 2 drachms. When there is costiveness, chebulic myrobalans are substituted for ginger in the above prescription. (Chakradatta.) The use of pepper for the cure of intermittents is strongly recommended by Stephanus in his commentary on Galen, and recently some cases of refractory intermittent fever, in which, after the failure of quinine, piperine has been administered with advantage, are reported by Dr. C. S. Taylor (Brit. Med. Journ., Sept., 1886). In one case, immediately on the accession of an attack, three grains of piperine were given every hour, until eighteen grains had been taken, and on the following day, when the intermission was complete, the same dose was given every three hours. Mahometan physicians describe black pepper as deobstruent, resolvent, and alexipharmic; as a nervine tonic it is given internally, and applied externally in paralytic affections; in toothache it is used as a mouth-wash. Asa tonic and diges- tive, it is given in dyspepsia. With vinegar it forms a good IIL,—22 ; ; 170 - PIPERACE Zi. stimulating poultice. With honey it is useful in coughs and colds. Moreover, it is diuretic and emmenagogue, and a good stimulant in cases of bites by venomous reptiles. Strong friction with pepper, onions, and salt is said to make the hair grow again upon the bald patches left by ringworm of the scalp. They notice the use of the unripe fruit, preserved in salt and water as a pickle, by the natives of Malabar. De Gubernatis draws attention to the following passage from the travels of Vincenzo Maria da Santa Caterina (iv., 3) with reference to white pepper being offered by the Hindus to th gods in Malabar:—“Da Malavarié tenuto in stima grandissima, eli Gentili d’ordinario Voffrono a ‘loro Dei, si per la rarita come per la virti salutifera e medicinale, che da quello sperimentan riportandolo poi alli infermi.” For the early history of pepp in Europe, the Pharmacographia may be consulted. Cultivation.—Its cultivation is very simple, and is effected b cuttings or suckers put down before the commencement of rains in June. The soil should be rich, but if too much moistut be allowed to accumulate near the roots, the young plants apt to rot. In three years the vine begins to bear. They planted chiefly in hilly districts, but thrive well enough in low country in the moist climate of Malabar. They are usual planted at the base of trees which have rough or prickly such as the jack, the erythrina, cashewnut, mango-tree, ail others of similar description. They will climb about 20 or feet, but are purposely kept lower than that. During t growth it is requisite to remove all suckers, and the vine sho be pruned, thinned, and kept clean of weeds. After the ber _ have been gathered, they are dried on mats in the sun, turning from red to black. They must be plucked before they are q are smaller, of greyish-white colour, and have a less aromatic oF pungent taste. The pepper-vine is very common in the hilly districts of Travancore, especially in the Cottayam, M and Chenganacherry districts, where, at an average PIPERACEHA. iva about 5,000 candies are producedannually. Itisa Government monopoly. (Drury.) Description.—The immature fruit, known as Black Pepper, is globular, about 4 of an inch in diameter, much wrinkled, and of a brown-black colour; on one side are the remains of the peduncle, and on the other of the style and stigmas. ‘The pericarp is closely adherent to the seed. The latter consists of a thin reddish-brown testa and a copious albumen, the exterior portion of which is horny and the interior farinaceous. The embryo is wndeveloped. The mature seed, knownas White Pepper, is less acrid than Black, as the pericarp has been removed; it is also rather smaller and of a grey colour, striated from base to apex by about a dozen light stripes. The transverse section of a grain of black pepper exhibits a soft, yellowish epidermis covering the outer pericarp. This is formed of a closely-packed yellow layer of large, mostly radially arranged, thick-walled cells, each containing in its small cavity a mass of dark-brown resin, The middle layer of the pericarp consists of soft, tangentially-extended parenchyme, containing an abundance of extremely smallstarch granules and drops of oil. The shrinking of this loose middle layer is the chief cause of the deep wrinkles on the surface of the berry. The next inner layer of the pericarp exhibits towards its circumference, tangentially-arranged soft parenchyme, the cells of which _ possess either spiral striation or spiral fibres, but towards the interior, loose parenchyme free from starch and containing very _ large oil cells. ___ The testa is formed in the first place of a row of small yellow thick-walled cells. Next to them follows the true testa, as _ a dense, dark-brown layer of lignified cells, the individual out- __ lines of which are undistinguishable. The albumen of the seed consists of angular, radially arrang- , large-celled parenchyme. Most of its cells are colourless " loaded with starch ; others contain a soft, yellow, amorphous s. If thin slices are kept under glycerine for some time, 172 PIPERACEZ. these masses are slowly transformed into needle-shaped crystals @ of piperin. (Pharmacographia.) Chemical composition.—Black pepper contains an acrid resif, a volatile oil, starch, gum, a small quantity of fatty oil in the mesocarp, and about 5 per cent. of inorganic matter, besides alkaloid piperine, and a volatile alkaloid which is probably iden- tical with piperidine. The acrid resin is dark-green, soluble in alcohol, ether and alkalies, and, in connection with ot constituents of pepper, also in water. C. Heisch (Analyst 186-190) has shown that pepper should contain not less than per cent. of starch, which is characterised by the smallness of granules. The essential oil has been examined by L. A. 0°87352 at 15° C., and showed a Shige: 2 colour, due neit chlorophyll nor to copper. At 22° the oil had a leevorot power of 3-2°in acolumn 100mm. long. On recti a very small quantity passed over at 160°. Fractions obte at 170°, 176° and 180° were colourless; that obtained at faint green, and that at 250° green, that passing over at brown-green. Above 310° a brown, tenacious residue obtained in which phenol could not be detected. The ee tion, when rectified under reduced pressure, gave a boiling at 164°—165°, and showed a Tet herded 9 of 7°6° in 100 mm.; it gave numbers agreeing wi formula C*°H"*.. The composition of the other fractions was much the this. The oil consists of a levorotatory terpene and i compounds of higher boiling point. (Journ. Chem. Soe 1887; Year-Book Pharm., 1888. _ Pure piperine crystallizes in colourless flat, four-sided p' of a glassy lustre and almost tasteless, As usually met with, is of a yellowish colour, inodorous, and has at first a sligh ti a sharp. PIPERACEH. 173 and in 1 part of boiling 80 per cent. alcohol ( Witéstein), and freely in acetic acid; the last two solutions are precipitated on the addition of water. It is likewise soluble in chloroform, © benzol, and benzin. At 129° C. it melts like wax to a yellowish oily liquid, which on cooling congeals toa mass of resinous appearance ; when fused it may be ignited, and burns with a bright flame, leaving a light charcoal, which is readily consumed by heating it in the air. Sulphuric acid colours it blood-red, the colour disappearing on the addition of water, leaving the piperine unaltered if the action of the acid has not _been prolonged (Pelletier). The solution of piperine in sulphuric acid is yellow, becoming dark-brown, and finally green-brown (Dragendorff). Nitric acid colours piperine successively greenish- yellow, orange, and red, and dissolves it with a yellow colour, the solution separating yellow floccules on the addition of water ; by prolonging the action of the acid, oxalic acid and a yellow bitter compound are produced (Pelletier). The resin resulting _ from this reaction becomes blood-red on the addition of potassa, and on heating the mixture piperidine is given off (Anderson, 1850). Piperine is a very weak base, and its salts are decom- posed by water; crystallizable double salts, soluble in alcohol, may be obtained with the chlorides of mercury, platinum, and cadmium. By dry distillation with soda-lime piperidine is — obtained. Boiled with alcoholic solution of potassa, piperine was _ found by Babo and Keller (1856) to be resolved into piperic acid, C”’H'°O*, and piperidine, C?H'*N. Piperic acid is in hair- like, yellowish, needles which fuse at 150° C., and at a higher temperature volatilize partly unaltered, at the same time giving off a coumarin-like odour. Piperidine is a colourless liquid of an ammoniacal and pepper-like odour, and when largely diluted of a bitter taste. It boils at 106°C., has a strong alkaline reaction, dissolves freely in water and alcohol, and yields with acids crystallizable salts; the piperate of piperidine crystallizes in silky scales, which, on being heated, give off a part of the 4 ‘Pyridine with sodium. (National Dispensatory.) Heisch 174 PIPERACEZ. (Analyst, ne 8 Ler the following analysis of pure and com- 2/28 Sieelos ls es 23 Pe eet bss 1s Esl 3 Pee 5 Sy agian Gee ae a ee 3 $ |g8/25/23 \438| 8 | se 4 ae < BEY. ae an |< 9-22) 4°35) 1°54| 1-51] -36| -73| 48°53 Black berry “) to t to to | to 14-36] 8-93) 3°34 | 8-83) 4-38 |1-57| 56°67 ¢| 18°67) 1-28) -217) -84) +22 |... | 76-27 White berry ... t t ° oO to (| 17-32, 8-78] -618| 2-8o| -69 | -22| 77-68 Fine — saree vee L890, 1. “DSL “16 A, “531. ef TORE Bas pepne er vs. 12°15) 13°48) 2°28 | 5-52) 5-68 | -53) 58°78 Aes ound .. ..s...1 11°12) 14°7 | 2°02 | 4-07] 8-61 | -78| 35°85 W. Johnstone (Chem. News, Nov., 1889) has shown pepper. contains a volatile alkaloid probably identical 1 piperidine. Black pepper yielded 0°56 per cent., and the bi alone 0:74 per cent., of this base. White pepper yielded it: but in smaller qienkty and the larger proportion of pi in the husk, the author considers to be an explanation of greater pungency of black pepper as compared with ¥ pepper. Long pepper was found to yield 0°34 per cent. ‘ alkaloid. (Year-Book Pharm., 1889.) Commerce.—The exports of pepper from the Malabar C : —_ —_ a 6 years have been— oe ee me e PIPERACE. 175 Aduiter ation, —As pepper is always sold whole in India, it is seldom adulterated. We have occasionally met with an admix- ture of the berries of Embelia Ribes, and the fruit of Mirabilis Jalapa is stated to be sometimes mixed with it. The abortive berries of P. troicium, Rovd., now considered to be the wild form of P. nigrum, are known in Western India as Pokali-miri, and the plant as Kokervel in Marathi and Murial- tiga in Telugu. Garcia d’ Orta notices the drug under the name of Canarese pepper, and observes that it never finds its way to Portugal, but is valued as a medicine by the natives to purge the brain of phlegm, to relieve toothache, and as a remedy for cholera. This plant was first described by Roxburgh, who f6und it growing wild in the hills north of Samulcotta. It was growing plentifully about every valley among the hills, delighting in a moist rich soil, and well shaded by trees; the flowers appearing in September and October, and the berries ripening in March. Roxburgh commenced a large plantation, and in 1789 it contained about 40,000 or 50,000 pepper-vines, occupying about 50 acres of land. The produce was great, about 1,000 vines yielding from 500 to 1,000 lbs. of berries. He discovered that the pepper of the female vines did not ripen properly, but dropped while green, and that when dried it had not the pungency of the common pepper; whereas the pepper of those plants which had the hermaphrodite and female flowers mixed on the same ament was exceedingly pun- gent, and was reckoned by the merchants equal to the best Malabar pepper. Pliny (12,14) mentions abortive pepper seeds known by the name of ‘‘ Bregma,” a word which in the Indian language sig- nifies ‘dead. ’’ He remarks that it is the most pungent kind of pepper. Lendi-pipali. Globular catkins of a Species of pepper occasionally found in the Bombay market, said to come from _ Singapore, They are of the size of the pellets of sheep’s dung, hence the name Lend{-p{pali. The taste is very hot and acrid. 176 PIPERACEL. The individual fruits are nearly as large as cardamom seeds, the — whole catkin having much the appearance of a small black berry. PIPER CHABA, Hunter. Fig.—Miq. Ill. Pip., t. 34; Hayne, Arnz., Gewachs. t. 21; Wight Ic., t. 1927. Long Pepper (Zng.), Poivre to (Fr.). Hab.—Cultivated in India and the Malay Islands. fruit and stem. Vernacular.—Chab (Hind.), Chai (Beng.), Chavak (Mar.). PIPER LONGUM, Linn. Fig.—Bentl. and Trim., t. 244; Mig. Ill. Pip., t. 30; # Arnz. Gewachs. wiv., t. 20; Wight Ic., t. 1928; Rheede Mal. vii., ¢. 14. Hab.—Hotter provinces of India. The fruit and re Vernacular.—The fruit.—Pipal, Pippali (Hind.), (Zam.), Pippallu (Tel.), Tippali (Mai.), Yippali (Can. (Beng.), Bangéli-pipali(Mar.), Pipara (Guz.). The root palscart Pipla-mil, Pipla-mur (Hind.), Tippili-mulam, » pili-vér (Zam.), Modi, Pippali-katta (Tei.), Tonia Q epee (Beng.), Pipali-miil (Mar., Guz.). e History, Uses, &c.—Aswe have already stabil we _ ithighly probable that long pepper was the kind of pepper | known to the ancient inhabitants of Western Asia a au (See P. nigrum.) In Sanskrit works on medicine, P. 1 described under the name of Pippali, and bears the evn Chapalé, Péla, Mgadhi “growing in South Bihar,” : Shaundi, &c. It is considered to be digestive, sweet, cold, _- oMpeeoliont and io ‘useful in rheumatism, aoe PIPERACEA. 177 equal parts, is prescribed by several writers as a useful com- bination for catarrh and hoarseness. As an alterative tonic, long pepper is recommended for use in a peculiar manner. An infusion of three long peppers is to be taken with honey on the first day, then for ten successive days the dose is to be increased by three peppers every day, so that on the tenth day the patient will take thirty at one _ dose. Then the dose is to be gradually reduced by three daily, and finally the medicine is to be omitted. Thus administered, it is said to act as a valuable alterative tonic in paraplegia, _ chronic cough, enlargements of the spleen and other abdominal __ viscera. Long pepper and black pepper enter into the composi- tion of several irritating snuffs; boiled with ginger, mustard oil, buttermilk and curds it forms a liniment used in sciatica and paralysis. In the Concan the roasted aments. are beaten ap with honey and given in rheumatism; they are also given powdered with black pepper and rock salt (two. parts of long pepper, three of black, and one of salt) in half tola doses for colic. Mahometan writers, under the name of Darfilfil, describe long pepper as a resolvent. of cold humours; they say it removes. obstructions of the liver and spleen, and _ promotes.digestion by its tonic properties; moreover, it is.aphro- disiacal, diuretic, and emmenagogue. Both it and the root _ (Filfil-muiyeh) are much prescribed in palsy, gout, lumbago, _ and other diseases of a similar nature. A collyrium of long _ pepper is recommended for night blindness; made into. a lini- _ ment it is applied to the bites of venomous reptiles. We learn _ from Roxburgh ( Flora Indica, L., p. 155) “that it is in Bengal only that Piper longum is cultivated for its pepper. When the ament is full-grown, it is gathered and daily exposed to the. sun till perfectly dry; after which it is packed in bags for sale, The roots and thickest part of the creeping stems, when cut into small pieces and dried, form a considerable article of commerce all over India, under the name of Pippali-mula, for which pur- pose it is particularly cultivated in many of the valleys ae e Sircar mountains. This sort is more esteem d bears a higher price than that of Bengal, where by fin, pe ae 3 TH.—23 178 ‘PIPRRACEA. portion is cultivated. It, as well as the pepper, is chiefly 4 employed medicinally, and the consumption of beth these drugs a is very great.” Piper longum was formerly cultivated at Poway, near Bombay; it appears to grow well in gardens in Bombay, but requires plenty of manure. = Pippali-mula, with the synonyms Kana-mula, Katu-granthi, : Ushana-granthika, Chataka and Chataka-shira, is described m the Nighantas as having the same properties as long pepPe? P. Chaba, which produces the long pepper of European bens! merce, is the Chavi, Chavika and Chavya of Sanskrit writers. _It is considered to have the same properties as P. /ongw™. The aments are sold in the bazars as Mothi pippali, and the stem a8 Chab, Chai or Chavak, — The oblong black pepper of Theophrastus (H. P., ix., 22) was probably long pepper. Dioscorides, in his article upon the three peppers, mentions a pepper root, and says it resembles Costus, has : a hot taste, and causes salivation when chewed. This drug was “probably Galangal, which is known as Pén-ki-jar or root < e Piper Betle, because its odour somewhat resembles that © _ Betle leaves. ig tate men, © : is oceupied by the sm embryo. The colourof commercial long aie is greyish-white, as if it had been rolled in some earthy powder. When washed _the spikes are reddish-brown, The drug has a burning arom® — PIPERACE4. 199 aroma, but in the process of drying it gradually developes an aromatie taste and odour. Pippali-mula, or pepper root, when fresh, is a fleshy, crooked, and knotted root about the size of a goose-quill, with many smaller rootlets branching from it. The cortical portion is very thick, and covered by a thin smooth brown epidermis. The central woody column is.soft and divided into from 4 to 6 wedge- shaped portions by from 4 to 6 very conspicuous medullary rays, Microscopie structure.—The epidermis of the root consists of several rows of tangentially extended brown cells. ‘Fhe paren- chyme of the cortex is chiefly composed of large thin-walled cells loaded with starch, and containing drops of essential oil. Amongst them are scattered cells containing a refractive yel- low substance (resin). The central woody column is also loaded with starch, and contains as many resin-cells as. the cortex, The medullary rays are abundantly provided with large scalari-_ form vessels. Chemical compoesition.—The constituents ef long pepper are the same as those of black pepper. A third kind of long pepper is met with in the bazars, which is known as Swaheli or Sugandhi-pippali, and is imported from Zanzibar. It has a peculiarly fragrant odour, and is a tered with honey as a remedy for cough; it has not the svi _ of the other long peppers. : he aments are from 1 to 24 inches in length, flexuose, mang _ of them barren or nearly so, only one or two fruits having come _ to maturity. These aments are almost filiform. The peduncle is about one inch long. The mature fruit after being soaked in water is 345 inch in diameter, pyriform, mucronate {the mucro bifurcated), sessile ;it consists of a pulpy envelope enclosing a somewhat pyriform seed resembling in structure that of other peppers. Commerce.—Three kinds of long pepper are met with in the Indian market—Ilst, Singapore, which is identical with the long pepper of European commerce ; 2nd, Bangéli, the produce of P. longum, cultivated in Bengal; 3rd, Srenliclig imported from 180 PIPERACER. Value, Singapore, Rs. 7 to Rs. 12 per maund of 41 Ibs. Bengal, Rs. 9; Zanzibar, Rs. 5. Pippali-mul is also of three kinds: Mirzapore, Rs. 10 to Rs. 40; Bengal, Rs. 7 to Rs. 18 Malwa, Rs. 50 per maund of 41 lbs. PIPER CUBEBA, Linn. f. Fig.—Benti. and Trim.,t.248. Cubebs (Eng.), Cubébes (Ei) Hab.—Java. The fruit. Vernacular.— Kabéb-chini, Kankol (Hind. ’), Kankola (I Val-milaku (Zam.), Toka-miriyalu, Chalava-miriyalu (1 Val-mulaka (Ma/.), Bala-menasu (Can.), Chini-kabab (@ - History, Uses, &c.—Cubebs were introduced medicine by the Arabian physicians of the Middle 4 Masudi in the 10th century stated them to be a production | - Java, The author of the Sthah, who died in 1006, desert) Kababeh as a certain medicine of China. Ibn Sina, about t same time, notices it as having the properties of madder, b more agreeable taste, and states that it is said to possess and cold properties, but is really hot and dry in the degree, a good deobstruent, and useful as an applica’ putrid sores and pustules in the mouth ; it is also good for voice and for hepatic obstructions ;a valuable diuretic, expe gravel and stone from the kidneys and bladder. He con by stating that the application of the saliva, after chew increases “the sexual orgasm. Later Mahometan writer similar accounts of Kababeh, and say that it is called Hab-e “ bridegroom’s berry,” and that Greek names for it are Ma _ (#axAév?), and Karfiyun, evidently a corruption of xapmnqio% _ name of an aromatic wood mentioned by Paulus Aigineta. — appears that cubebs were at one time known as Fructus cay siorum in Europe. In the Raja Nirghanta, which was writt about 600 years ago, cubebs appear under the name of K and the samename appears inthe Hindi and Marathi Nighat Madanpal gives Katuka-kola, “pungent pepper,” as a synony for it. All the Sanskrit names appear to be of compere recent origin, The authors of the ree we PIP#RACEA. 181 attention to the fact that the action of cubebs upon the urino- genital organs, though known to the old Arabian physicians, was unknown to modern European writers on Materia Medica at the commencement of the present century. According to Crawfurd, its importation into Europe, which had long been discontinued, recommenced in 1815, in consequence of its medicinal virtues having been brought to the knowledge of the English medical officers serving in Java, by their Hindu servants. (Op. cit., 2nd Ed., p. 585.) In earlier times cubeb pepper was used in Europe asa spice, as it still is, to some extent, in the East. Description.—The fruits are elevated on a kind of stalk, formed from the contraction of the base of the fruit itself, so that they are not really but only apparently stalked. The dry berries are spherical, wrinkled, of a brown colour, and are easily distinguished from black pepper by the pedicel at their base; beneath the pericarp is a nut which contains the seed. The albumen is white and oily. As the fruit is gathered when immature, the drug usually consists of little else than the pericarp. The mature fruit which is sometimes met with in the Indian Bazars should be rejected. Microscopie structure.—The pericarp consists of an epidermis, beneath which is an interrupted row of small thick-walled cells. Within this the parenchyme is composed of cells containing starch and oil; in the latter, bundles of needle-shaped crystals of cubebin may be observed; lastly, the innermost layer of the pericarp is formed by several rows of tangentially extended cells containing essential oil. The nut is yellow and brittle The seed when present is seen to contain crystals of cubebin, Chemical composition.—The most obvious constituent of cubebs is the volatile oil, the proportion of which yielded by the drug varies from 4 to 13 per cent. The oil, when freshly distilled, is slightly greenish, but becomes colourless on rectification, It has the odour of cubebs, and a warm aromatic comphoraceous taste. Its density varies between 920 and 936 at 15°C. The causes of the great variation in the yield of oil may be found in- dissolves freely i in §iolling alcohol, but is mostly deposites 182 PIPERACE A. the constitution of the drug itself, as well as in thse alterabilit of the oil, and the fact that its prevailing constituents d not begin to boil below 264°C. Cubeb oil was shown Db Ovlialore to be a mixture of a turpene boiling at 158° 163°, which is present to a very small amount, and two of the formula C'°H**, boiling at 262° to 265° €. One the latter deviates: the plane ‘of polarization strongly to th left, and yields a erystalline compound, "HCl, melti at 118°C. The other hydrocarbon is less lwvegyrate, does not combine with HCl. (Deut. Chem. Ges. Ber., 1357.) Cubeb oil mixes with glacial acetic acid in all tions; iodine gives a violet coloration without perceptil reaction ; with nitric acid it becomes opaque, and on heating pale red tint is afforded. (Brannt.) One part of oil, dil with about 20 parts of bisulphide of carbon, assumes at irs greenish, and afterwards a blue coloration, if one drop af mixture of equal weights of concentrated sulphuric and niti acids is shaken with “the solution. The oil distilled f cubebs, on cooling after a time, is stated to deposit large, parent, inodorous octohedra of camphor of cubebs, C?°H* + 2 belonging to the rhombic system, which melt at 63°, pablime at 145°. But the authors of Pharmacographia f to obtain crystals after keeping the oil of fresh cubebs for years in contact with water, to which a little nitric acid been added. ' Another constituent of cubebs is ( Mubebin, crystals of © may sometimes be seen in the pericarp even with a commo ~ It was discovered by Soubeiran and Capitaine in 1839 ; inodorous substance, crystallizing in small needles or melting at 125°, having a bitter taste in alcoholic solution. ited u ; cooling; it requires 30 parts of cold ether for solution, and is —_— soluble in chloroform. Fliickiger and Ha d this solution to be slightly levogyre, a to turn ee of concentrated sulphuric acid. If the soluti eubebin in chloroform is shaken with phosphoric anhyd1 tees turns ~ and gradi red 0: n abso PIPERACEZ. 183 moisture. Cubebin is nearly insoluble in eold, but slightly soluble in hot water. Bernatzik (1866) obtained from ecubebs 0°40 per cent. of cubebin, Schmidt (1870) 2°5 per cent. The crystals, which are deposited in an alcoholic or ethereal extract of cubebs, consist of impure cubebin. Cubebin is devoid of any remarkable therapeutic action ; its composition, according to Weidel (1877), answers to the formula C’*H"°O* ; by melting it with caustic potash, if is resolved into acetic and protocatechuic acids. : 2 The resin extracted from cubebs consists of an indifferent portion nearly 3 per cent., and of Cubebic Acid, amounting to about 1 per cent. of the drug. Both are amorphous, according to Schmidt, like the salts of cubebic acid. Bernatzik, however, found some, as the barium salt, to be erystallizable. Schulze (1873) prepared cubebic acid from the crystallized sodium-salt, but was unable to obtain it crystalline. The resins, the indifferent as well as the acid, possess the therapeutic properties of the drag. Schmidt further pointed out the presence in cubebs of gum (8 per cent.), fatty oil, and malates of magnesium and calcium. The yield of ash, according to Warnecke, is 5°45 per cent. Commerce.—Bombay is supplied with the dreg from Singa- pore. There is a good demand for it, and the consumption in native practice appears to be increasing. Value—Formerly cubebs was obtainable in the Indian markets at from 4 to 5 annas per lb., but for the last eight years the price has been seldem less than Re. } per lb. PIPER BETLE, Linn. Fig.— Wight Ic., t. 2926 ; Mig. Til. Pip., ¢. 39; Bot. Mag., €. 3132; Rheede, Hort. Mal. vii., t.15. Betle Pepper (Enyg.), Porvrier de Betel (Fr.). Hab.—Cultivated in the hotter parts of India, Ceylon, and Malay Islands. The leaves. — Vernacular,—Pan (Hind., Beng., Guz., Mar. ), Vettilai ( Zam.), Naga-valli (7el.), Vetrila (Mad), Viledele (Can.). 184 , PIPERACE. History, Uses, &c.—According to the Hitopadesa, the Betle-leaf (taémbila) has thirteen properties (Tambilasya tray dasha gunih svarge’pi te durlabhah). It is sour, bitter, heatin, sweet, salt, astringent ; it expels flatulence (vataghna), phlegm (kaphanisana), worms (krimihara); it removes bad odours beautifies the mouth, cleans it, and excites voluptuous sensations. According to Hindu tradition, the plant (Ndga-valli) wa brought from heaven by Arjuna, who stole a branch of it, which he planted on his return toearth. The leaves with Betle-nut and spices form the vira, or pén-stipari, so much used by the nativ India as a token of civility oraffection. Itisalso given in confirm ation of a pledge, promise, or betrothal, and, among the Raj is Sometimes exchanged asa challenge; thus the expression uthana signifies “to take up the gauntlet,” or take upon © self any enterprise ; bira dalna, “to propose a premium” # the performance of a task: the phrase originated in a cus instance, in the first story of the “ Vetalapanchavinshati,” king, when he sends the courtesan to seduce the penitent W4 was suspended from a tree, nourishing himself with a sm Kt gives her a bira, ira dena signifies “‘to dismiss” either | courteous sense or otherwise. A dira is sometimes the ¢¢ of a bribe, and a bira of seven leaves (sat pan ka bira) 18 8&2 by the father of the bride to the bridegroom as a sign © betroth: t marriages the bride or bridegroom places a vi" cigarette-shaped viva between the teeth, for the other party . partake of by biting off the projecting half; one of the tricks played on such occasions is to conceal a small piece of stick _ this viri, so that the biting it in two is not an easy matter. The betle-leaf was probably the Malabathron or Indian 1 of the Greeks, sometimes called simply “leaf” (¢vAAsv), and sold in rolls in a dried state. Dioscorides speaks of its being thread- ed on strings to dry, a practice which, before the introduction _ of steam carriage by sea, was common in Bombay among the Indian traders who sent the leaves to their friends at foreig® ports. The passage in Dioscorides év tT@ pedavitely re dpavator ei PIPERACEA. 185 oAdcAnpov is probably corrupt, and should be as suggested by his commentator, M. Vergilius, €v Tw padaki€ew te GOpavorov Kai édoxAnpov, a reading which he found in one manuscript. As regards the fabulous growth of Malabathron as recorded by Dioscorides, it may possibly have originated from a confused account of the method of ripening betle leaves followed in some parts of India. The author of the Makhzan states that the leaves, which, when plucked, are always green, are packed in a large kind of basket and covered with rice or wheat straw. A hole is then dug in the ground, of the size of the basket, and a fire lighted in it until the ground becomes warm. The fire is then removed, and the basket of leaves is placed in the hole and covered with stones or any heavy weight so as to press the leaves together; it is kept in this position for 24 hours, and after removal the basket is exposed to the night dew, if it is the hot season, or kept in a warm place, if it is the eold season, until the leavesare of a pale yellow colour and become brittle. That Malabathron was not a cinnamon leaf, is, we think, clear from Dioscorides in his chapter on Cassia, describing its leaves as like those of the pepper plant, thus showing that he was acquainted with cinnamon leaves as distinct from Malabathron. Ibn Sima describes Témbitil as cold and dry, astringent and desiccative, and notices its use by the Hindus. The author of the Makhzan-el-Adwiya, who wrote in India, gives a full account of the different varieties of Betle-leaf produced by cultivation; of the method of ripening the leaves for the market; and of their properties and uses. Dott (Hind. Mat. Med., p. 244) has the following concise account of their uses:—< The leaves of this creeper are, as is well known, masticated by the natives of India. The poorer classes make their packet of betle with the addition of lime, catechu, and betle-nuts. The rich add cardamoms, nutmegs, cloves, camphor, and other aromatics; betle-leaf thus chewed acts as a gentle stimulant and exhilarant. Those accustomed to its use feel a sense of langour when deprived of it. The ancient Hindu writers recommend that betle-leaf should be taken early in the morning, after meals and at bed-time. According to IIT,—24 Jena, has found that the essential oil is of much use in cata 186 PIPERACED. a Susruta, it is aromatic, carminative, stimulant, and astringent It sweetens the breath, improves the voice, and removes all foulness from the mouth. According to other writers it acti as an aphrodisiac. Medicinally it is said to be useful in diseases supposed to be caused by deranged phlegm, and its juice much used as an adjunct to pills administered in these diseases, the pills being rubbed into an emulsion with the juice of used as a domestic remedy in various ways. ‘The stalk of the leaf smeared with oil is introduced into the rectum in consti] tion and tympanitis of children, with the object of inducing bowels to act. The leaves are applied to the temples in headae for relieving pain, to painful and swollen glands for promo checking the secretion of milk. Pén leaves are u a Aseeey for foul ulcers, which seem to improve 4 them The spittle, after chewing pan sipéri, is red, and is fi ejected by natives, preferably over recently white- walls ; the dry stains are often mistaken by the police for bl stains, and pieces of plaster, leaves, grass, &c., thus we have frequently been forwarded to the Chemical Exam Bengal, for detection of blood ! Of late years the medicinal properties of betle leaves been investigated in Europe. Dr. Kleinstuck of Zwatzen, Culdination, —The betle mer (pdén-mala) is a work of | The best site is the well-drained alluvial bank of a river or stream- : The vine is rather fond of an iron ob but lime, salt, or soda are fatal toit. The well must last throughout the year, be perf sweet, and not more than forty Se feet at deep, otherwise the . | PIPERACEA. 187 j raising the water eats up the greater part of the profits, The betle-leaf, it is said, cannot be grown from channel water, which is very cold. After the site has been chosen, the next point is to fence it from cattle, thieves, and strong winds. First is an outer line (kumpan) of substantial wicker-work, split bamboos, Zizyphus twigs, or other pliable material. Inside of this fence is a thick milk-bush hedge.* Then comes a belt of the large ___ castor plant, and last of all, a row of plantains. The garden is laid out in an invarying pattern. The whole, crosed by water _ channels and roads, forms beds of different shapes and sizes. Each bed, known by a particular name, such as the cheritang, the bertang, and the véfu, is stocked with a certain number of vines, so that the outturn and other particulars of a garden can be calculated with great nicety. After the ground has been laid out and properly levelled, tree seeds are sown for the vines _ totrainon. Round the edge of each bed is a line of shevri (Ses- bania egyptiaca), and in thecentre from two to three feet apart, the seeds of hadga (Sesbania grandiflora) and pangéra (Erythrina indica), and from four to six feet apart, single seeds of the nimb (Melia Azadirachta), are planted. In addition to these, the popar (Oarica Papaya), singly, and plantains in pairs are dotted about, according to the amount of shade required. These seeds are sown in the first week in June (mriga nakshatra), and after that, hand-weeding and watering every eight days is all that is wanted up to the end of December (pushya nakshatra), when the nurse-trees are eighteen inches to two feet high, or large enough for planting the-vines. From the tops of the best ripened _ shoots, in the old plantations, seven-inch cuttings are taken, _ They are first made into small bundles, wrapped in plantain leaves, soaked in the water they have been accustomed to, carried to the new plantation, soaked in the new water, and all but the tips buried in the ground. For some time water is given daily ; later on once in two days ; and afterwards, except during the hot months when it is given every other day, once in six days. From each unburied tip a shoot springs. When they are a few inches long, the shoots are led up the stems of the * Euphorbia neriifolia. s > 3k i haa, 188 PIPERACE. nurse-trees, and lightly tied with strips of a dried sedge — (path), so elastic that, without untying it, the pressure’ of the growing vine keeps it loose. When the vine has grown to the proper height, it is turned back and trained down until it reaches the ground, where it is layered in the earth — and again turned up. This is repeated until the tree-stem is” fully clothed with vines, when the whole is firmly tied with th dried reeds of the davéla* grass. After this the management of the plantation closely resembles the cultivation of the grape vine in Southern Europe. Leaf-pickmg may be begun eighteen months after planting, but in the best gardens it is put off ti the end of the second year. The leaves may be gathered green and ripened artificially, or they may be left to ripen on me — vine, though this reduces their value. Theleaf-picker uses both — which nip the leaves clean off without wrenching the p _ Fhe vine-grower is either himself a leaf-dealer, or he sells his crop in bulk to a leaf-dealer. 'Fheir table of measures is: 40 leaves make a kavli; 44 kavlis a kurtan; and four kurtans 70,400 leaves an ojhe. Im retail the leaves are sold at f p. 174.) 9 Description.—The leaves are about five inches I broadly ovate, acuminate, obliquely cordate at the base, 5 to i nerved, coriaceous, and. glossy on the upper surface : they hav a burning, aromatie and bitter taste. 2 Ms cashed composition.—L.. 8. Kemp of Bombay (1885), b peculiar odour of the leaf, but the light oil being more aromatic. These oils oxidised rapidly, losing their characteristic ethereal odour. The heavy oil was freely soluble in aleohol and ether; sparingly so in chloroform. It had a specific gravity of 1-046 at 84° F'., and was slightly levogyre, (a) j=—'54 for a eolumD 100 mm. long, Prof. J. F. Eijkman’s results with oil of betle, reper oot by this ata > » and mene wees Rak, are both PIPERACE, 189 distilled by himself from fresh leaves, which had been in part reported in 1888, have been communicated to the German Chemical Society (Berichte, 1889, pp. 2736-2754). The oil was pale greenish-yellow, became golden-yellow and brown on exposure, was slightly leevogyre, and had the sp. gr. 0-969 at 15°C. Caustic potash removed from the oil chavicol, a phenol of sp. gr. 1-030 at 15°C., boiling between 236° and 238°C., and having a peculiar odour, somewhat resembling that of creasote ; its composition is C9H'!°O ; its aqueous solution is coloured blue by ferric chloride, the colour disappearing on the addition of alcohol; its constitution is expressed by the formula OH (1) OF oops (3). The crude chavicol seems to contain a small quantity of a phenol of somewhat higher boiling point, and in aleoholic solution becoming blue with ferric chloride. Betle oil, freed from phenol, did not yield, on fractional distillation, a pure compound in sufficient quantity for examination. The ~ fraction between 173° and 176° contained several terpenes, but no pinene, and hada very agreeable lemon-like odour, while a mint-like odour was observed in the fraction between 190° and 220°, From the higher boiling fraction a hydrocarbon, sesquiterpene, was obtained, having a slight odour, boiling at 260° C., and in acetic solution acquiring a deep indigo-blue colour with bromine. Eijkman calls attention to the betle oil _ obtained by Schimmel & Co. from dried leaves, and shows that _ the oil did not contain the above compounds to which the fresh _ leaves owe their characteristic odour, and which must have been dissipated by drying, or oxidised by exposure, or lost by remaining dissolved in the water; the use of steam under pres- sure may have volatilized more of the high-boiling phenol than is obtainable by ordmary distillation. The oil distilled from the dry leaves by Messrs. Schimmel & Co. was a slightly brown-coloured liquid, sp. gr. 1024 at 15°C. It consisted up to about % or 3? of a phenol, the boiling point of which in partial vacuum, under a pressure of 12 mm., lay at 131°—132° C,; under ordinary atmospheric pressure it 190 PIPERAOE. underwent decomposition on boiling. The sp. gr. of the phenol — was 1-067 at 15°C. Examination of the oxidation products, acetyl compound and methyl ether, showed that this compound was not eugenol, but an isomer, the composition of the new compound (iso-eugenol) and of eugenol being represented as follows :— aa Tso-eugenol, Eugenol. Or (1) O° H® ¢f) O° H® {on (3) ag Be } ocr (3) OC H* (4) H (4) The second constituent of the oil boiled practically between — 250° and 275° C., had a very agreeable tea-like odour, a consisted for the greater part of a sesquiterpene Cc’ cubebene, which is characterized by its dihydrochlorate mé at 117°—118°C. (Berichte von Schimmel & Co., 1887.) _ At the Narturforscher Meeting in 1888, Professor Eijkm reported that among the constituents of the essential oil distill from fresh betle leaves, he had found a characteristic compout having the odour of the leaves and the constitution of p phenol, which he designated “chavicol,”? About the same u Messrs. Schimmel announced that the phenol present in higher-boiling factions of the oil distilled from air-dried leaves corresponded completely with eugenol, though su sequently they hey & ee ee Ere, ee ae ph 1 oht: ! ed by them was not eugenol, but an isomer (Pharm. Journ. xix., 803.) With a view to clearing up the apparent ¢ diction, Prof. Eijkman has re-examined the oil distilled himself from the fresh leaves, and some distilled from dry | ae Messrs. Schimmel, with the result of confirmin g the presence in the former of chayvicol, boiling at 236° to 238° C., and in thé latter of the isomer of eugenol, boiling at 254° to 255°, which ‘proved to be orthomethoxychavicol (Berichte, xxii., 2735) _ It would seem probable, therefore, that both phenols occur in the leaves, and that chavicol being the more volatile, had practically disappeared from the dried leaves, while the method of distill: Hon adopted by Messrs. Sc aimmel favoured the more comp! PIPBRACER. | 191 removal of the higher-boiling compound. Some experiments made with chavicol are said to have shown it to be a powerful antiseptic, it being five times stronger as a bacteriacide than carbolic acid, and twice as strong as eugenol, (Pharm. Journ., Nov. 30th, 1889.) A sample of oil distilled from fresh betel leaves in Manila, at the request of Messrs. Schimmel, is described as of a golden yellow colour, possessing a pronounced odour of betelphenol and having a specific gravity of 1-044 at 15° C, The phenol was separated from the oil by the method of Bertram and Gildemeister, and during the purification by distillation at a _ pressure of 11 mm. it passed over quite regularly between 128° 4 and 129°, a behaviour that pointed to a homogeneous body. _ By treatment of the phenol with benzoyl chloride a benzoyl 4 compound was obtained that crystallized in scales and melted 4 at 50°. It was evident that this was not a mixture of benzoyl _ compounds, as the portion that crystallized first had the same a melting-point as that which crystallized last; it followed, _ therefore, that it represented no other phenol than betelphenol. _ Other constituents occur in this oil only in a small quantity, and of these, to judge from the boiling point, terpenes form only a small fraction. The results of the examination of betel oil up to the present time may therefore be summed up as follows :— (1) Oil distilled from fresh leaves from Java (Eijkman), contained besides terpenes and other bodies, chavicol and betelphenol. _ (2) Oil from dried Siam leaves consisted of sesquiterpene and betelphenol. (3) Oil distilled from fresh leaves (Java) contained terpenes, betelphenol and a small quantity of another phenol (probably chavicol), the nature of which could not be determined, from want of material (melting point of the benzoyl composed 72°-73°). (4) Oil from fresh leaves distilled in Manila contained no her phenol than betelphenol. J 192 MYRISTICEA. Betelphenol was contained in all the oils, whether derived from Java, Siam or Manila, or from fresh or dry leaves; . would therefore appear to be a characteristic constituent | betle oil. (Berichte v. Schimmel & Co., Oct. 1891.) MYRISTICE, MYRISTICA FRAGRANS, Houtt. Fig.—Bentl. and Trim., t. 218 ; Reichb. des i. t. 276-2 Nees, Pl. Med., t. 1383; Rumph. Herb. Amb., ii., t. 4. Nut (Zing.), Muscade (Fr.), Mace (Eng.), Macis (F). Hab.—Moluccas. Cultivated in Penang, Malay I and Zanzibar. The seeds and arillus. Vernacular.—Nutmegs—Jaiphal (Hind., Beng., Guz. Jadikai (Tam.), Jaji-kaya (Tel.), Jéjikayi (Can.), Jatikka Mace—Javitri, Jépatri( Hind.), J&dipattiri (Tam.), Jépatri Tel.), Jétipattiri (Mal.), Jotri (Beng.), Jayapatri (Mar), oe Japatri (Guz.). History, Uses, &c.—Natmegs, in Sanskrit Tati Jatiphala, are mentioned by Susruta, and in the Nighantas various synonyms, such as J&ti-kosha, Jati-sara, Shélika, Majja-sdra ; they are considered to be hot, digestive, ca mi expectorant and anthelmintic. Mace iscalled J. Ati-pattri, a said to have similar properties. Both of these spices provi became known in India through the Hindu colonists in Java the Eastern Islands. From India they would appear reached Persia and Eastern Europe. The authors Pharmacographia remark that nutmegs were probably kn sant Constantinople about the year 540. The Arabs e first became acquainted with nutmegs through the Pe as their name Jouz-bawwa is a corruption of the P Gauz-i-buya, “fragrant nut.” Masudi, who travelled in | East in A.D. 916—920, oe ons they were MYRISTICR ZA. 193 from the Zerbid Islands. Ibn Sina describes both nutmegs and mace (Basbiseh). Edrisi, who wrote in the middle of the 12th century, mentions both nutmegs and mace (Basbdseh) as articles of impert into Aden. By the end of the 12th century both of these spices were well known in Continental EKurope. Mir Muhummad Husain says that the Dutch keep the trade in their own hands, but that he has heard that the tree is now. ____ cultivated inSounda in Southern India. Whether he was rightly informed with regard to Sounda, we are unable to say. But that his information was substantially correct, there can be no doubt, as Ainslie tells us that in his time the true nutmeg tree was growing in the Tinnevelly District, and produced pretty good fruit. The tree has also been introduced into Ceylen and Zanzibar, and appears to flourish in the warm moist climates of those islands. Mahometan doctors describe nutmegs and mace as stimulating, narcotic, digestive, tonic, and aphrodisiac, useful in choleraic external application in nervous headache, palsy, &c.; applied round the eyes it is thought to strengthen the sight. The expressed oil of nutmegs is imported into India from Banda, andis known | as Jawitri-ka-tel (oil of mace). It was formerly exclusively brought into European commerce v?é Holland, in oblong cakes having nearly the form of common bricks, but somewhat smaller, and packed in monocotyledonous leaves, commonly _ called “flag leaves.” At the present time much of the oil is _ Manufactured in Europe, and put up in the same shape, but packed in paper. When discoloured and hardened by age, the oil is called “ Banda soap.” Oil of mace is manufactured by exposing imperfect and broken nutmegs, reduced to a paste and enclosed in a bag, to steam, and then pressing the bag _ between heated iron plates. The yield is about 20 to 23 per cent. (Brannt.) The bark of the tree is astringent. (Pereira, Mat. Med., ii., p. 475.) We have found nutmegs and their — T.—25 194, MY RISTICEZ. essential oil a valuable adjunct to other drugs in the treatmen of diarrhea and dysentery ; they appear to relieve the pain. Description.—The following excellent description of the nutmeg fruit is taken from the Pharmacographia :— The fr of Myristica fragrans is a pendulous, globose drupe, abo 2 inches in diameter, and not unlike a small round pear. It marked by a furrow which passes round it, and by which a maturity its thick fleshy pericarp splits into two pieces, exhi- biting in its interior a single seed, enveloped in a fleshy foli ceous mantle or arillus, of fine erimson hue, which is m The dark-brown, shining ovate seed is marked with impressions corresponding to the lobes of the arillus; and on one side, whick is of paler hue and slightly flattened, a line indicating t raphe may be observed. _ The bony testa does not find its way into European commerce the so-called nutmeg being merely the kernel or nacleas of # seed. Nutmegs exhibit neatly the form of their outers with a corresponding diminution in size. The London des esteem them in proportion to their size, the largest, which a about one inch long by 8, of an inch broad, and four of w will weigh an ounce, fetching the highest price. If not dre with lime, they are of a greyish-brown, smooth yet coarsel rowed and veined lon gitudinally, marked on the flatter si with a shallow groove. A transverse section shows that inner seed coat (endopleura) penetrates into the albume long, narrow brown strips, reaching the centre of the s aromatic fragrance, with a spicy rather acrid taste.” The expressed oil of nutmeg is of the consistence of tallow, _more friable, orange-coloured, and of a fragrant, spicy 1 and odour. It has a Sp. gr. of 990 (Brannt), 2 MY RISTIOCLA. 195 Microscopie structure.—The brown covering of the nutmeg is formed by the endopleura, which also dips in and forms numer- eus processes which divide the albumen in every direction; it is composed of soft-walled brown cells, which on the external surface are small and flat, but much larger in the processes already mentioned. The cell-structure of the albumen is load- ed with starch and fatty matter, some of which is crystalline. Herr A. Tschirch states that the aril of Myristica fragrans furnishes a good illustration of the presence of amylodextrin as a normal cell-content in the place of starch. It is distinguish- ed from true starch by being stained reddish-brown instead of blue by an aqueous solution of iodine. The grains of amylo- dextrin are from 2 to 10 » in diameter, and do not appear to contain even a nucleus of starch. They have usually some- what the form of a rod, and are often curved or coiled ; less often they are roundish or disc-shaped; they do not usually exhibit any evident stratification. Chemical composition.—Nutmegs contain from 2 to 8 per cent. of volatile oil, 25 to 30 per cent. of fat, starch, protein compounds, &c. The most volatile portion of the oil, after treat- ment with sodium, was found, by Cloéz, to be a levogyre hy-. drocarbon, C!°H'®, having the odour: of the nut, and boiling at 165°C. It is the myristicene of Gladstone, who named the oxy- genated portion myristicol, C!°H!*O ; this is dextrogyre, boils at 224° C., and does not, like menthol and carvol, yield a crystalline eompound with H’S, The nutmeg camphor of John, or myristicin of Gmelin, which separates sometimes.on standing, was ascer- tained by Fliickiger to be myristic acid. From the expressed oil of nutmeg or nutmeg butter, cold alcohol dissolves about 6 per cent. of volatile oil and 24 per cent. of fat, accompanied by brown-yellow resinous matter, which has not been further examined. The remaining: pulverulent white fat is myristin, C°H*(C*H"0*)*, which crystallizes from hot alcohol or ether and fuses at 31°C. Heintz found the melting-point of myristic acid to be 53°8°C. Schmidt and Remer found 3 to 4 _ per cent. of free myristic acid, with a little stearic acid. -— : old Mahometan physicians ‘have been confirmed by Rumphius, 196 MY RISTICEA. The most important constituent of mace is the volatile o which is present to the amount of about 8 per cent., bul terpene, C'°H"®, called macene, which yields a crystallizab compound with ee acid gas, and appeurs to be aa to, but, by Koller, considered identical with, the myristicene ¢ oil of nutmeg. The oxygenated portion of the volatile is still less known than the terpene. Henry found red soluble, and yellow fat insoluble, in alcohel, but the 24°5 per ¢ residue obtained. by Fliickiger (Pharmacographia} with boil ether and drying at 100° C. appeared to have consisted sol resin and semi-resinified volatile oil. The same author 0 with aleohol I 04 per cent. of uncrystallizable sugar, hot water 1-8 per cent. of a body which turned blue, drying reddish-violet, with iodine, and is probably inte between starch and mucilage. (Wational Disp.) J. & ( Berichte, 23, 1803) has faolatad: by fractional distillation mace or rather nutmeg oil, a bod sessing the I of mace, which he jitls fh yristictn, and which has. the com represented by C’*H'"O*. The correctness of the fo controlled by the preparation of a bromine derivative myristicin, C’*H'*Br? O*, which melts at 105° C. | According to Warnecke, powdered nutmegs yield 41-2 cent. of fat when boiled for two hours in a reflux cond with benzol, and the dried residual powder gives 3°77 per of ash. Mace yields 1:39 per cent. of ash, and after 1 of 30°13 per cent. of fat, 2°74 per cent. | Toxicology.—The narcotic effects of nutmegs noticed D Lobel, Schmid and Cullen, and more ook ments upon man and animals agree in showing | that have a narcotic and intoxicating: ection. Ina a case Cullen, tw, MYRISTICEA,. 197 Commerce.—Value, Re. 1-4-0 to Re. 1-8-0 per Ib. The nut- megs imported into India run from 100 to 180 to the pound; the larger seeds never make their appearance in this market. In- deed the native retail dealers prefer small seeds, as they buy by weight and sell by number. MYRISTICA MALABARICA, Lamk. Fig.—Bedd. Fl. Sylv., t. 269; Rheede, Hort. Mail. iv., t. 5. Hab.—Concan, Canara, N. Malabar. The seed and arillus, Vernacular.—Ran-jaiphal, Rémphal (Mar.), Panam-palka (Mal.\. The Mace—Rémpatri (Mar., Guz.). History, Uses, &c,—This drug does not appear to have been known to the older Hindu and Mahometan medical writers, _ but the following extract from the Makhzan-el-Adwiya seems _ toapply toit. Speaking of true nutmegs, the author says :— _ ‘Latterly the English have discovered a kind of nutmeg in _ Southern India, which is longer than the true nutmeg and softer, but is much inferior to it in oiliness, odour, and medicinal properties,” (Makhzan, article “ Jouz-bawwa.”’) Itisthe Vue myristiea mas of Clusius, and the Panam-palea of _ Rheede, who says that the Turkish and Jewish merchants use _ the nutmegs and mace for adulteration. Rumpbius (i.,185) notices it under the name of Mannetjes-nooten, and states that it is used by the Javanese and Malays asa remedy for headache and as an aphrodisiac, and is worn round the neck as a protection from boils. It is also used by the Indians in Amboyna, com- bined with opium and roasted unripe plantains, in dysentery. According to the editor of the Pharmacopeia of India, the seed is used medicinally in the Madras Presidency; it yields, when bruised and subjected to boiling, a considerable quantity of - concrete oil, analogous to expressed oil of nutmeg, which is said _ to be an efficacious application to indolent ulcers, allaying pain _ and establishing healthy action. An ointment may be made by _ melting it with sweet oil. The seeds are used for similar pur- poses in Bombay in the form ofa /ép, and the oil is also extracted. 198 MYRISTICEZL. Recently, the arillus, under the name of ‘Bombay mace,” has — made its appearance in the European markets, for the purpose of adulterating true mace. (Confer. A. Fschireh in Phaxmaceut. Zeitung, 1881, No. 74.) In Bombay it is used as a spice. : Description.—M. malabarica bears an oblong, tawny, hairy fruit, 24 to 3 inches long, with a lucumose arillus, the lobes of which are twisted and folded into a cone at the top and are longer and thinner than those of true mace. 41 arillus is of a dark brownish-red colour, and on the inside h adhering to it a thin papery membrance of a light-brown colou The shell § is hard and brittle, and contains an elongated kernel resembling a nutmeg, and from 1} to 2 inches long; when cv in two it is seen to have the same ruminated structure, but t odour is fruity, with hardly any aroma, Similarly, the is deficient in odour and flavour. | Microscopic structure—The epidermal cells of the arillus radially elongated, narrow, and twice as high as those of | mace, which are tangentially elongated ; their walls show q cellulose reaction with iodine and sulphuric acid, and with chi ride of zinc and iodine swell and turn faintly blue. The ¢ cells are very numerous, located near the epidermis on bo sides, often close together in groups. of two or three, 0 shape, somewhat radially elongated, and contain a dark-y I usually, resinified oil, frequently also a brownish resin. Tschirch.) The external covering of the seed is formed by the compressed cells of the endopleura, and is thicker than that of the trué nutmeg; the processes which penetrate the albu are composed of very large cells loaded with a viscid reddish- brown substance, which has an astringent and somewhat taste. The albumen is composed of -large cells loaded with starch ; some of the cells and their contents are of a reddit brown colour. There is no crystalline fat visible. Towicology. —Rumphius relates that in 1683 a minister of Amboyna was given by his wife three roasted nuts, in mistake for ~ideepe. * to cure a chronic diarrhea; in a few hours he became giddy, ~— —— ee and aed ic nor LAURINEZ. 199 _ did he get any relief until he had taken several cups of tea and _ been blooded. He then slept profoundly and perspired very _ freely. On waking, no bad effects remained, and the diarrhea _ had ceased. Rumphius remarks that if he had taken three real nutmegs, he would have suffered much more. — Commerce.—Rémpatri is now worth about Rs. 10 per maund of 373 lbs.; formerly it was much cheaper. The nutmegs fetch Rs. 2 per maund of 37% Ibs. According to Dr. Hefelmann, the 4 adulteration of powdered mace in Germany generally consists in the addition of Bo.nbay mace, or of other vegetable material (leguminous fruits) coloured with turmeric. The presence of _ the latter is shown by the presence of starch cells which are not " present in mace. Bombay mace may be detected by boiling the suspected sample with alcohol and filtering through a white _ filter; in the case of pure mace, the filter is stained a faint _ yellow, but in the presence of Bombay mace, the filter, especially | 4 the edge, is coloured red. Another more delicate test is to _ add Goulard’s extract to the alcoholic filtrate; with pure mace _ only a white turbidity is occasioned, but when Bombay mace - is present, a red turbidity is obtained. The reaction given by _ turmeric is similar, but it may be distinguished from that of _ Bombay mace in the following manner:—A strip of filter paper is saturated with the alcoholic solution, the excess of fluid removed, and the strip drawn through a cold saturated solution of boric acid; when Bombay mace is present, the paper remains unchanged, but in the presence of turmeric it turns orange-brown. Ifa drop of potassium hydrate solution is now Placed on the strip of paper, it causes a blue ring if turmeric ‘is present, and a red ring if the adulterant is Bombay mace,— (Pharm. Zeit, 1891,.122.) LAURINEA. CINNAMOMUM CAMPHORA, Nees. Fig. —Bentl. and Trim., t. 222; Woodv. Med. Bot., t, 286; Nees, t. 180; Berg. et Sch., t. 10, €.; Wight Ic., t. 1818. Cam- -phor (£ng.), Camphre (Fr.), 200 LAURINEA. Hab.—China, Japan. Camphor and Oil of Camphor. -Vernacular.—Kafér (Hind.), Karppiram, Shédan (7 am.), i Karptram (7el., Mal.), Karpura (Qun.), Kapir, Kaphtr (Beng.), Kapir (Mar., Guz.). f History, Uses, &c.— ‘in the hall at Christmas. 298 LORANTHACEA. The dried berries sold in the bazars as Kismish-kawali, of more correctly Kismish-i-kdwaliydn, are also called Muizak-i-asli, and in Arabic, Dibk. a Kéwali or Kauli is the name of a gipsy tribe in Persia. 4 Baron ©. A. de Bode, in his Travels in Luristan and Arabistan — (Vol. IL., p. 100), mentions his being shown in the forests of : the Zagros mountains, on the road from Kirmanshah to Baghdad, “ a fruit called by the natives Angur-1-Kault, or grapes of the 3 Kauli, which grow on the Mazu or gall-tree (oak), of a yellows — ish transparent colour, sometimes used as glue. The hakim Déwid says of Dibk (in a passage which i¢ imperfect in the Téj el Ards) “it is found upon the tree in like manner as lichen (¢asJ!), but is a berry, like the ehiekpea ween) im roundness; . . . . the best thereof is the smooth, soft, with much moisture, inclining, in its exterior, to greenness, and it is mostly found upon the oak; when it is eooked with honey and ,.--? o (juice of fresh dates, &c.) . and drawn out into longish strings, and put upon trees, the birds become caught by it.” (Madd el Kémis.) The author of the Makhzan-el-Adwiya has the following account of it A berry ~smaller than the seed of Cicer arietinum, green whet fresh, but when dry shrivelled and of a brown colour, the com tents are moist and viscid, the seeds about the size of poppy” seeds. The plant is parasitic upon the pear and other tree and consists of several branches, the leaves are like those of the pomegranate, and of a pale green. Properties resolvent and laxative, a solvent of corrupt humors which it withdraws from the system. When steeped in hot water, strained, and beaten up with the kernels of the walnut or castor oil (which is the usual form of administration), it clears the system of adust bile and phlegm, removes obstructions, and is a remedy for Tambago, piles, &c. Applied externally it promotes the suppuration, oF barber the dispersion of tumors or enlargements. SportsmeP use it as birdlime, and dyers as a mordant for crimson.” _ OF recent years, mistleloe has again attracted attention a8 # — medicine. Dr. W. H. Long (New Remedies, 1878, p. 112) aftets ja ti SSRAME Righelig Wai a LORANTHACEH, 299 ten years’ experience of it as an oxytocic, arrived at the conclu- sion that it is superior to ergot. He used it also in the forms of infusion, tincture, decoetion and fluid extract in many cases of menorrhagia and post-partum hemorrhage with gratifying results. He conceived that it incited the nataral, rather than the tonic, contraction of the uterus. A physician in South Carolina refers to three cases of abortion in negroes produced by this plant. (Ded. Rec., xvii., 276 ; Stillé and Maisch., Nat. Disp., 1884, p. 1617.) Dr. R. Park speaks of a tineture of Viscum album as-a valuable substitute for Digitalis; the ecbolic action of the plant, he says, is more energetic than that of ergot. Dose, 10—60 grains. Description.—The dried berries are about 4 of an inch in diameter, soft, brown, and shrivelled ; they contain a small seed about the size of a poppy-seed. When crushed they are very sticky. Chemical composition.—M. Pavlevsky (Bull. Soc. Chim. (2), xxxiv., 348) has obtained from the leaves of V. album a erystallizable acid corresponding to the formula CH*O* or (CH?0*) HO. It forms large prisms insoluble in alcohol and ether, slightly soluble in water, and fusing at 101—103°C. It is obtained by boiling the leaves with water acidulated with nitric acid, and allowing the decoction to cool. The silver salt of this acid is explosive. (Year-Book of Pharm., 1881, p. 63.) The berries contain a substance which has been named Viscin by Reinsch, who obtained it from birdlime by digesting it with 90 per cent. alcohol as long as it coloured that liquid yellow, after which it was boiled repeatedly with alcohol to remove “wax. The remaining yellowish-brown mass, when treated five or six times with ether, gave up viscin, whilst viscaoutchin and woody fibre remained undissolved. The ethereal solution was then evaporated, and the viscid yellow mass thus obtained kneaded with alcohol so long as it gave off colouring matter, It was then kneaded under water, and heated to 120°, without access of air, until the whole of the water was expelled. Viscin is a clear transparent mass, of the consistence of honey 230 EORANTHACE 2. at ordinary temperatures, and capable of being drawn. out: into long threads; fluid at 100°, like oil of almonds; sp. gr. 1. It produces a greasy stain on paper, is nearly inodorous and tasteless, and has an acid reaction. Formula C*°H“0". Viscaoutchin remains behind, together with woody fibre, after the extraction of viscin by ether as above, and is taken up by 01 of turpentine. After distilling off the turpentine, the yellowish mass is dissolved in ether, in which it has now become soluble; _ the ethereal solution is evaporated, and the residue is washed with alcohol and water, and dried at 120°. At ordinary temperatures it is viscid, and resembles vegetable wax; at 120° it is of the consistence of olive oil. It is very elastic, and may be drawn out into long threads; sp. gr. 0°978. It is tasteless, of faint odour and neutral reaction. Formula C*°H370°. (Gmelin, xvii., p. 352.) Viscum et Loranthus, sp. var. In the Pharmacopwia or India, the leaves of a Viscum, doubtfully referred to . monoicum (Kuchila ke molung), growing on Nux Vomica trees in the neighbourhood of Cuttack, are stated to possess poisonous properties similar to those of the tree on which the plant grows. The subject was investigated in 1837 by Sir Ww. O’Shaughnessy, who is said to have detected in the powdered leaves the presence of strychnine and brucine: and the leaves were for a time used by Dr. Duncan Stewart and others 48 a substitute for Nux Vomica. A case of what is stated 1? have been fatal poisoning by the leaves is mentioned by Norman Chevers in his work on Indian Medical Jurisprudence. The symptoms were those of strychnia poisoning. In 1861 Mr. Leon Souberain (Pharm. Journ., p. 568) published an account of a poisonous species of Loranthus found on the Nilgiris, growing on Nux Vomica trees, and known to the natives as Poulourivi, : In Pudukota, a decoction of a species of Loranthus called Pillooroovi or Kooroonthoo, probably the same plant, is applied to skin diseases to relieve itching. ; Under the name of Bandékpushp, the flowers of Loranthus longiflorus, Desrouss., Rheede, Hort, Mal., z., t. 4, have been sent LORANTHACEH. 231 tous from Poona as having a reputation among the Hindus as a remedy in consumption, asthma, and mania; they are astringent. Dr. Buchanan-Hamilton, when in Mysore, was shown the — Loranthus faicatus, Linn. (‘Wotu,’ Canarese), the bark of which was used by the poorer natives in place of betel-nut; with _ quicklime it tinges the saliva and mouth of a fine red, brighter _ even than that communicated by the Areca. In Travancore, the Loranthaceous parasites on the Nux _ Vomica are called Kanjiram-eitthal in Malayalim, and are used in _ medicine by the natives, but when the parasites are scarce, the young leaves of the Nux Vomica tree are used as a substitute. A contribution by M. A. Chatin to the Paris Academy of - _ Sciences entirely contradicts the statement we have extracted from the Pharmacopeia of India, and the belief of the natives that these parasites partake of the nature of the plants upon _ which they grow; so that the old ideas concerning the non- _ elaboration of sap by parasitic plants will have to be abandoned. __ M. Chatin finds that the tannin of the mistletoe is not identical with that of the oak on which it grows, but gives a _ green colour and not a blue-black with iron salts; that the _ Loranthus, which grows on Strychnos Nuw Vomica, does not, as has been asserted, contain a trace of either strychnine or — colour of the wood of its host plant, nor does the Orobanche of he hemp possess the odour of the latter ; while Hydnora yfricana, used as food in South Africa by the Hottentots, grows m anacrid and even vesicating Euphorbia. It is evident, therefore, that the sap absorbed from the host plant must be modified by the parasite to form its own peculiar products. _ (Pharm. Journ., May 2nd, 1891.) The Forest Officer of Ganjam, a district where the Strychnos grows so plentifully, sent to one of us a specimen of a species Viscum taken from these trees, which was identified as e 232 SANTALACE. V. articulatum. The sample was asmall one, but it was sufficient to determine by analysis that the trace of alkaloid present was neither strychnine nor brucine. The leaves contained a pecu- iar tannic acid, giving a green precipitate with ferric salts, and a resin soluble in ether and alcohol, striking a blood-red colour with strong sulphuric acid. The chemical constituents of the leaves of the parasite were altogether different to those of the leaves of the Nux Vomica tree. SANTALACE/. SANTALUM ALBUM, Linn. Fig.— Bedd, Fl. Sylv., t. 256; Hayne, Arne. Gewachs. @, f.1; Bentl. and Trim., t. 292; Rumph. Amb, ii., t. 11. San- dalwood (£ng.), Santal blanc (F’r.). Hab.-—Deccan Peninsula. The wood and essential oil. Vernacular.—Chandan, Sufed-chandan (Hind.), Sandanak- kattai (Tam.), Gandhapu-chekka (Te/.), Chandana-mutti (Mal.), Gandhada-chekke (Can.), Chandon, Sada-chandon ( Beng-)s Chandana, Sukhada (Guz.), Chandana, Gandha-che-khor {Mar.). History, Uses, &c.—Sanskrit writers make two kinds of Chandana: the darker, heartwood, they call Pitachandana, or yellow Sandal ; and the lighter wood, Srikhanda, or white Sandal. Chandana is mentioned in the Nirukta, or writings of Yaska, the oldest Vedic commentary extant, said to be written not later than the 5th century B.C. It is also referred to in the ancient epic poems of the Hindus, the Ramayana and Mahabharata. According tothe Kathdsaritségara, it is one of the trees of the Buddhic paradise, and the chariot of the sun is made of it wood bound with gold. | Sanskrit medical writers describe sandalwood as_bittet cooling, astringent, and useful in bilious fever and heat of body + SANTALACEH. 033 FS? ROAST NEON Sel ee EM zi a paste of the wood is directed to be applied externally to in- : flammatory affections of the skin, and is adomestic remedy forall kinds of pains andaches. Under the name of gandh (perfume), it is largely used in Hindu ceremonial, being smeared upon idols and upon the foreheads of their worshippers. The wood ‘is chiefly consumed at the chita or funeral pile, even compara- tively poor people spending as much as fifty rupees upon it. The Parsees also use it at their funeral ceremonies. Mahometan medical writers, commencing with Masih and Ibn Sina, call the wood Sandal, and follow the Hindus in distinguishing the dark-coloured portion from the light. The author of the Makhzan describes it as cold anddry, cardiacal, tonic, astringent, alexipharmic, antaphrodisiac, a resolvent of inflammatory swellings, &c. He recommends an emulsion in bilious fever, on account of its cooling and protective influence over the heart, brain, stomach, &c, Asan external application a paste made with rosewater and camphor, or with sarcocolla and white ofegg, may be applied to relieve headache, or to any kind of inflammatory swelling or skin affection. Sometimes the paste is made with the juices of herbs, such as purslane, nightshade, &c. Ainslie states that in Southern India sandalwood given with milk is regarded as a valuable remedy in gonorrhea. Rumpbhius (ii., p. 42) mentions a similar use of it at Amboyna. In the Concan sandalwood oil with cardamoms and bamboo manna is given in gonorrhea, and mixed with limejuice and camphor it is used as a cooling application to eruptions, &c. A conserve of sandal- wood is also made by boiling the wood cut in small pieces in bangar-khér (impure carbonate of potash) and water (4 seers sandal, half a seer bangar-khér, and 32 seers water), until it is quite soft. It is then preserved ina thick syrup. Sandalwood _ was known to the Greeks from the time of Alexander. Arrian mentions éiAa cayadiva among the Indian imports into Oman in the Persian Gulf. Constantinus Africanus, a physician of the School of Salerno, appears to have been the first to use it medicinally in Europe. In the Pharmacopeia of India, Dr. Ai. Ross is stated to have subjected the wood to me: and _ found that whilst its effects as a stimulant were be? & III.—30 ‘Si URAC arts Cees re yee a lee eee eee 2. oS Ae ee ee eee) eds ba * TE Ee ee SO a CT en ree ee Ce ee ; d “284 SANTALACEZ. secondary effect was that of a sedative on the circulation. In remittent fevers in which it was administered, it acted asa diaphoretic, diminishing at the same time the rapidity rather than the violence of the heart’s action. Dr. Henderson, of Glasgow, and, in France, Drs. Panas, Gubler and Simmonet, have directed the attention of European physicians to the valuable properties of the oil as remedy for gonorrheea, in doses of from 30 to 40 minims three times a day, and there is new some demand for it in India for this purpose. Petes Dr. Henderson asserts that he always found it inoffensive, evel in strong doses ; that at the expiration of forty-eight hourscom- = plete relief is effected ; besides, it has the important qualification : of pleasing the patient and being agreeable to the stomach ; itis superior to copaiba and cubebs, succeeding where the latter have failed, and with a delicate subject it is to be highly valued as @ remedy uniting a real stomachic to a great specific action, and that, in short, during the last five years, he is indebted to it for a great number of successful cases. (Medical Times and Gaz., June 1865.) In a communication to the Paris Chirurgical Society, Dr. Panas (1865) equally advoeated ita use. Oleum Santali has also been prescribed in chronic catarrh of the bladder, where it performs the same offices as oil of turpentine, without - its injurious effect on the kidneys and alimentary canal. In all cases it is best administered in the form of Midy’s Capsules, teB to twelve of which may be given daily at first, divided into three doses, each of which may be taken a quarter of an hour before meals; the number of capsules taken daily may be gradually increased to 24, but as soon as the discharge becomes serous, the dose should be gradually diminished. M. CO. Méhw has observ that after the internal administration of oil of sandalwood, # resinous substance is found in the urine having the odour of the wood, which appears to be kept in solution by phosphate of soda, and which has the properties of a very weak acid. Tb resinous substance can only be obtained in very small quantities = eG ee thea Fe ee PRT Wily a oe tba PENI AES Rf Se OF SS SRT NP tase tk ho et. eda | oo ae by shaking the urine with ether ; to obtain it in larger quantity; an acid must be used (phosphoric or tartaric), which makes ¢ he resinous matter, Ifthe utné Pon. 3 SANTALACE®, 235 P is now shaken with ether, and the ether evaporated, the resinous matter is obtained of a light-brown colour, and having the odour _ f sandalwood. This substance in contact with concentrated pure oil of sandalwood, M. Méhu has also observed that the pure sandal oil does not communicate a violet odour to the urine, as is the case when the oil is adulterated with copaiba and tur- pentine. (Journ. de Pharm. et de Chim., Sept. 1st, 1886.) The fact ofa resin being precipitated by acids from the urine in eases in which sandalwood oil has been administered, has therefore to be remembered in testing for albumen with nitric : Description.—Sandalweod logs are about a yard in length and 5 to 6 inches in diameter; they are stripped of the bark and a portion ef the sapwood. Andreas Petersen of Copen- hagen, who mde in 1886 a very careful investigation of the Rood, says :—‘‘ It is very homogeneous, rather hard and pon- ; derous, although it does not sink in water. The heartwood is pale reddish, with darker reddish-brown and brighter yellowish concentric zones, which, when examined under the microscope, _ prove to be annual rings. In the inner part of the wood they q are sometimes very wide, measuring, for instance, as much as seven millimetres. Possibly, charafone they do not correspond _ to one year’s growth, but to-that of a longer period. “The transverse section, examined by means of a lens, dis- _ plays the numerous narrow medullary rays ; the vessels are _ partly empty, partly loaded with yellow resin. In the bright yellowish sapwood both vessels and medullary rays are less distinct. The sapwood is scentless, whereas the heartw ood, especially when freshly cut, is in a high degree possessed of the very agreeable and remarkably persistent odour of sandal oil. ‘‘ The miscroscope shows the prevailing part of the tissue of the wood to be made up of ligneous fibres (libriform), the thick walls of which are marked with small annular pits (behétte Tiipfel). e woody tissue is traversed by medullary rays consisting of the same difference, although less distinctly. Thus the dark 236 SANTALACEA., one or two rows of somewhat irregular cells. On a transverse section, the distance of the medullary rays from each other is very different. According to the size and position of the vessels, the medullary rays are somewhat undulated. Most of the vessels are very large, the largest as much as 89 mkm. im diameter. They are very regularly distributed, either isolated, or in groups of two or three, very seldom more. Their walls — are very thick, being marked with numerous annular pits, communicating with those of the surrounding cells, There is also to be met with in the wood, parenchymatous tissue to some ~ extent, which is made up either of isolated cells or of short tangential or oblique rays of two to five cells; these parenchy- matous layers very seldom run from one medullary ray bed another. Crystals of oxalate of calcium are also found; and in longitudinal sections they are seen to be enclosed in long ducts, containing each 10—15 crystals. As to the concentri¢ zones of darker and brighter tint, as mentioned above, the ; vessels of the latter zones are much smaller and less numerous — ‘than those of the dark ones; the libriform cells likewise show zones in all probability represent the wood built up in spmng The vessels have an average diameter of 74 mkm., those of the — vessels in the other rings being only 47 mkm. ; _ “The darker colouris due partly to the actual cell-walls, partly to the resin contained in numerous vessels, On the whole, the concentric markings or zones are more distinct to the naked ey® than under the microscope. On a vertical section the medullary rays are seen to be built up of usually less than eighteen layoyy” ch consisting of two or three rows of cells, The position lullary rays and pits does not allow this wood to be classed among the woods which were described by Héhnel as showing the remarkably regular arrangement of layers or series Ke stories, which he termed a ‘stockwerkihnliche’ structure. If these slices of the wood are boiled for some minutes with nitric. acid (1°185), a little chlorate of potassium being added, the single cells are easily isolated. The libriform cells are distinotly Seen to e: typic form alluded to above, a few 4 SANTALACEH, 037 them reminding one extremely of the fibres, of which the ynewood is made up. I have also noticed intermediate fibres, marked with both true annular and laterally extended pn 3 Bisuring matter. The parenchymatous part of the wood, the medullary rays and numerous vessels are loaded with a yellow-brownish resinous matter. Thin slices, examined under water or glycerine, display a great many smaller and larger ops, soluble in alcohol and reducing osmic acid (1 part dis- ed in 100 parts of water); no doubt they are drops of essential These drops, flowing out of the ducts, on thin sections are most abounding along the primary membranes of the cells in their pits. But if rather thick sections are treated with mic acid, the woody parenchyme and the medullary rays also sume a black colour, due to reduced osmium. If, on the con- y, the sections, before being treated with osmic acid, have | well washed with alcohol, the just mentioned parenchyme ot at all or but extremely faintly blackened. The cells chromate of potassium and chloride of iron, the reduction of 6 osmic acid is consequently not due to tannic matter. Small of the heartwood were further treated for some days with lution of osmic acid, then extracted by means of alcohol and ed. When sections were made from these pieces, I ascertained that nearly all the parenchymatous parts had assumed a black colour. Sometimes also the libriform cells contain a small nount of oil, but the experiments just mentioned prove the nchymatous tissue of the wood to be the principal seat of the ial of, When treated with a mixture of ei pa 238 SANTALACE. glycerine and solution of potash (5 per cent.), oil drops are also distinctly seen in the parenchyme. I ascertained that there is no corky membrane in the walls of these cells, like a that occurring in many other cases. From a physiological — point of view, the absence of corky walls of the cells the heartwood might be expected.” (Pharm. Journ. (8) xvi., 757.) Pe Chemical composition.—The wood treated with boiling alcohol — yields about 7 per cent. of a blackish extract, from which a tannate is precipitated by alcoholic solution of acetate of lead. — Decomposed by sulphuretted hydrogen, the tannate yields a — tannic acid having but little colour, and striking a greenish hue with a ferric salt. The extract also contains a dark resin. (Pharmacographia.) The most interesting constituent of sandal- wood is the fragrant essential oil. It is a yellowish, remark: ably thick liquid, having a high specific gravity (usually more than 0-960); and is a mixture of hydrocarbons and oxygenated — oils, boiling at a very high temperature. The specific gravity of a pure sample of oil distilled at Hunsur from the roots was 0°9745 at 15°-5. M. Chapoteaut (Bull. Soc. Chim., XXXIV 303) has shown that it is composed of two oils, one boiling at 300° and the other at 310°, and that the composition of the oil boiling at 300° is C%H240, and of the oil boiling at 310° CHO, This chemist has been able to obtain with the latter oil a series of ethers under the influence of the different acids he brought to act upon it, and has announced the important fact that the oil C!*H°*O is a _ alcohol, the aldehyde of which is the oil ©'5H24O. Phosphori¢ anhydride absorbs water from both, converting them into. hydrocarbons of the formule C1°H?? and C!#H?+, respectively. By the Indian process only 2°5 per cent. of oil is obtained from the wood, but the powerful apparatus of Messrs. Schimmel & Oo. of Leipzig affords as much as 5 per cent. 8 Collection and Commerce.—Mr. C. E. M. Russell, Superinten™ _ Sent of Forests in Mysore, in a Report upon sandalwood (1889), ~~ cee — ‘ood is the most important source of Forest ~ SANTALACEH, 239 evenuein Mysore. Itisamonopoly of the Mysore Government, d, except by Government Agency, no sandal tree can be uprooted or cut down even upon land which is private property. The only exceptions are the Jahgirdar of Yelandur and the Guru of the Sringeri Matt, who are permitted to cut and dispose £ the sandalwood of theirown Jahgirs. The tree is plentifulin e Mysore country, and occurs also, but in far less quantities, in those portions of the Madras territory which border upon ysore; for practical purposes, however, Mysore may be said to almost hold the monopoly of the sandal supply. It isa dent upon a volatile oil which is contained in the heartwood only, and in order that this oil may be developed in the highest : Bele degree, it is necessary that the growth of the tree should be slow, consequently sandalwood grown in arid situations on poor stony soil is, though small, of far more value han is that produced by large well-grown trees growing in moist situations and in richer soil. The maturation period of ‘the sandal tree is variously stated at from 40 to 60 years, Sandalwood is not eaten by white ants, and its contained oil reserves it from decay in a remarkable degree, of which the . collection of old sandal roots left in the ground for . a custom not to uproot, but to fell, sandal trees, whereas for “many years past the trees have been uprooted, and the roots, which contain a higher percentage of oil than the wood, are in great demand and command high prices. _ “Even in periods of depression of the sandal market, a fair demand for roots has always been noticeable. The method of preparation is as follows :— “ The trees having been uprooted are roughly deprived of bark jnto the nearest of the sandal Kothis, of which nine exist in the Mysore Province, 240 SANTALACEZ. “The distribution of the various sandal Kothis and their names are :-— District. Number of Kothis. Names. Mysore 2 Hunsur and Seringapatam. Bangalore 1 Bangalore. Shimoga 4 Shimoga, Tirthahalli, Anantapur, and Shikarpur. Hassan x Hassan. Kadar — Chikmagalur. “On arrival at the Kothis, the trunks are sawn off above the roots, cut into lengths, all the white wood removed, the billets adzed and subsequently planed and smoothed, the roots adzed and freed of all adhering bark, mud, and white wood, and the various products —billets, ‘ehigs, small pieces, hollow wood, saw powder, &c.—collected and classified according to the classes represented by the specimens forming the sandal trophy: About the months of November and December auction-sales of the various classes are held in all the Kothis of the Province, and are so arranged, as regards the dates fixed for holding the same, that purchasers may, if they choose, attend the sales in Shimoga, Kadur and Hassan, and yet be in time for those in Mysore and in Bangalore. if Tir Mysore. Shimoga, Bangalore, Hassan. Kadur Years, a , di ; di ; d ; a ‘ i Sold. 5 i Sold. 3 : od i Sold. i fe 5 a jo @ jcoia| a | 5 a |5|a| @ Tons. ‘Tons. Rs. | Tons.| Tons.| Rs, |Tons/Tons) Rs. | Tons.| Tons.| Rs. ee Tons} Rs. 1882—83...... 574] 260} 96,877) 817} 849} 2,70,716)141%) 393) 17,049) 1853) 1623) 47,180)225 124 | 39,644 1883—84...... 217%} 808%) 73,728) 806 | 845] 2,71,626)108 ? 615] 241%) 2114] 70,550]1153) 90 | 20,220 1884—85...... 809} 3933) 1,15,082} 8843) 140 75,643) 13/2282) 52,595) 2603! 1933] 63,489] 683) 482) 12,954 1885—86...... 2613; 454) 1,57,308) 2612) 580 | 1,79,489]182 |1583) 38,405] 2273) 2743) 94,218] 782.1453 45,492 1886—87......| 521}, 493%) 1,46,367! 8963) 754}! 2,58,471,113 '164 | 63,604! 1874 194 71,490) 1662033) 75,480 1887—88......} 9403] 866$| 2,28,215) 798%| 8353] 2,58,893]184 159%) 56,811) 2309) 2543) 95,245.2119144}) 47,281 eee ; ay 2,762 8,17,027 8,964) $,9938| 18, 04,788}7293,7533| 2,29,079] 1,333}) 1,291| 4,43,172. 8653) 756) 2,41,071 —:savok 9 OF soinsy ey} Ure}TOD MoTOq SyUeMIE}e}S OY], ‘“WAOF Ivnqvz ul uUAOYS oq ATJUeTUaATOO UvO WOIfo1EY} Peatlop onuUsAdI oy} puv ‘poo jo pyerk ‘esuvr oy, —pooaynpuny ‘uwoif pansap anuaaay pun ‘fo pax pun abun ,, TFG WHOVIVINVS 942 SANTALACEA. Average Summary calculated on the 6 years. District, Collection, Sold. Revenue. pipes Tons. Tons. Rs. Shimoga District...... 6603 666 | 2,17,465 326} Mysore do. s.s+ 4702 463 | 1,36,171 294 Hassan do. wu... 999% 215 | 78,862 3435 Bangalore do. ...... 1212 125 38,180 305% Radar < do. ~...... 1442 126 40,178 319 po rate Years. Collection, Sold, Revenue. | per ton sold Tons, Tons. Rs. 1882—83 ....... 1,9123 1,4843 | 4,70,966 3284 1888—84 weccceee( 1,489 1456 | 4,36,739 300 1884—85 .....ceeee| —1,5238 1,0433 | 3,19,718 3064 1885-66... ent 1,568 5,14,862 3295 1886—87 veorsererversee} 1,844 | 1,8093 | 6,10,412 |. 3978 1887—88 .....ccecse0e] 2,9653 2,261 6,82,445 302 Perna 2a ee 9,7163 9,568 | 30,35,137 3i7 _ “Thus, the revenue from sandalwood in 1887-88 amounted to _ ho less than Rs. 6,82,445, while the average revenue for the 6 years reaches Rs. 5,05,856, “ There i ae but a slight variation between the prices obtained ~ for the various classes of sandal at the sales held in the yarious $ Kothis of the Province, so the prices obtained last year in the sete paint, Boat x a lower than those obtained in Sh font ke tela == a fair idea of the value of - SANTALAOEZ, 243 “Rates obtained in auction in the Mysore Districtin December . = Rs. per ton Ist coe taekentes logs) «O14 2nd clas 496 Sud nis (aS) gi 486 4th class (do) sa OT 5th class (logs) Cevecys 2 ANE Roots . 883 Jajpokal (ordinary commer cial) . ee Bagaradad (do. inferior) ..... 372 Powder . vee Ain Bagar (inferior wood) 311 Ain Chilta (common chips) Bee a 3 Hutri Chilta ‘saris do.) 168 Basola Bukni (adzed do.).. 47 Milva Chips (mixed do.) ....ce.ecssesey exe. Seay 85 “The yield of sandalwood from the Mysore Province is cap- _ able of expansion. Until recently little attention was paid to artificial reproduction and the encouragement and artificial _ enhancement of natural reproduction, the supply being obtained solely from natural growth. Now, however, extensive measures, pone for their object Sandal reproduction throughout the ~ Province, are being carried out, and no practical limit to the gs _ possible supply of this valuable tree, beyond the necessary ae question of demand, is conceivable. ee “ Ohief Markets for Sandalwood.—It will be matter for surprise that so valuable a wood, and one of- which a single Province _ may almost be said to hold the monopoly; should be so little _ known outside India. “The fact is that the trade in Mysore sandalwood has hitherto _ been confined to a ring, consisting chiefly of Muhammadan Seits, _ who either as principals or as agents of Bombay Firms, attend _ the local sales and send the sandalwood purchased by them to Bombay. The transit to Bombay from the coast is by sea in native craft. The Railways might perhaps secure this traffie if they offered special rates. eee «SANT ALACH AR. “The carts that convey the sandalwood to the coast are hired at low rates, as they are certain of return loads of salt and other merchandise to Mysore. Until recently, nearly all the sandal- wood sold in the auctions held by the Mysore Government, went to Bombay, but a demand haying lately arisen for sandal oil for medicinal purposes, some direct shipments of wood for extrac- tion of oil to France and Germany, and, probably, also to America, have been made.”’ A small quantity of sandalwood is produced in the Madras Presidency, and in the Bombay districts of North Canara and Dharwar. The following figures show the revenue obtained ‘from the wood in the Madras distwicts § in 1889-90 :— North Arcot...... Rs. 5,688 Average price, Bag ; per owt, South Arcot... Page 385 a) ”» ras PHN se 9 5,679 ry) ” ” 18 9 North Coimhatore ,, 194 39 % yw 1a x ESA oa vecee ing to ‘Horsfield, t ee call it Kayoo-oorb, also use LEE sh te Ae HUPHORBIACEA. O53 itasavesicant. Virey (i ist. Nat., p. 299) says :—II guérit tras bien |’affection venérienne ; il est aussi purgatif et vomitif.” Loureiro notices its caustic nature: ‘‘Occulos si tangat ex- eocat.” (Ainslie, Mat, Ind., ii., 183 and 425.) In the Concan 1 to 4 drops of the milky juice are given with treacle or the flour of Cicer arietinum as a purge, and the charcoal, which is very light, is used in making pastilles. Dr. G. Y. Hunter speaks of the j juice as a good application in neuralgia. In Goa it is used for poisoning fish. Description.—A shrub or il tree, 15—20 feet, with numerous slender branches, smooth, and of a bright~green colour, having afew, most minute leaves at the extremities, which soon fall off ; as the plant grows older, the stalks become stronger, and at length woody and of a brown colour. The wood of old trees is white, close-grained and strong ; it produces a good charcoal for gunpowder and other purposes. Chemical composition.—See next article, EUPHORBIA NERIIFOLIA, Jinn. Fig.--D0. Plant. Grasses, ii., t.46 ; Rumph. Herb. Amb. iv., t. 40. Hab.—Deccan Peninsula, Beluchistan, Malay Islands. Cultivated elsewhere. The juice and root. . Vernacular,—Sehund, Thohar (Hind.), Mansa-sij, Pata-sij (Beng.), Nevadunga, Mingtt (Mar.), Thohar-kantéro (Gus.), Tlaik- kalli (Tam.), Sioa ( Tel.), Yale-kalli (Can.), Elak- kalli (Mal.). EUPHORBIA ANTIQUOROD\M, Linz. Fig. — Wight Ic., t. 897 ; Rheede, Hort. Mal. i., ¢. 42. Hab .—tThroughout the hotter parts of India and Ceylon. The juice and root. Vernaculor.—Tidhaéra-sehund (Hind.), Tekéta-sij (Beng.), — Tridhéri-nevadunga, Nara-seja (Mar.), Shadhurak-kalli (Tam), 254, EUPHORBIACEA. Bomma-jemudu (TZe/.), Mudu-mula-kalli (Can.), Katak-kalli (Mal.), Tandhari-thohar (Guz.). History, Uses, &c.—These two plants are included under the Sanskrit names of Snuhi, Sehunda, Vajra, Vajra-tundi, Vajra-dantaka, Gandira and Maha-taru, and are supposed to ward off lightning strokes, on which account they are sometimes cultivated in pots placed on exposed positions in Hindu houses, They are sacred to Mansé, the goddess of serpents. In some parts of India, in July and August, on Tuesdays and Thurs- days, the natives approach the trees with offerings of rice, milk, and sugar, praying to be delivered from snake-bites. They also employ the root mixed with black pepper as 4 medicine for the cure of snake-bites internally and externally. Dutt informs us that in Bengal, on the fifth day after the full moon of the month Srawan, E. neriifolia is planted in the court- yard of Hindu houses and worshipped. In Western India there is a curious custom among the Con- cani Brahmins in connection with this plant. At the time of the Dewali they cut a portion of the stem, hollow it out, and fill it with oil, in which they place a wick. The little lamp thus formed is lighted and carried from house to house with the object of depositing it unextinguished in the house of some friend or acquaintance, saying at the same time, “A s0D- in-law for you,” that is, wishing them good fortune (Neva- dunga). The people of the house pretend not to want it, and try to extinguish the light by throwing water at it. These lamps are also placed upon little heaps of cowdung and _ worshipped. Tn the Nighantas the plants are described as purgative, pu- gent, digestive, bitter and heavy, and are said to be useful in constipation, flatulent distention, tumours, swellings, abdominal enlargements, rheumatism, spleen, leprosy, mania and jaundice, They abound in an acrid milky juice, which is a popular application to warts and other cutancous affections. The native doctors purity ‘arsenious acid by packing it in a hole lie aes ics io EUPHORBIACEZ. 255 made in a piece of the stem, closing the -hole and exposing the stem to the action of fire until it is charred. The milky juice of £. neriifolia is usually administered internally by soaking other purgatives and aromatics in it, so that by absorption of the juice their purgative properties become increased. A similar method is adopted when the juice is applied externally, a tent or issue pea being prepared with some finely powdered drug and steeped in it. Ainslie tells us that the native practitioners prescribe the juice as a purge and deobstruent, in those visceral obstructions and dropsical affec- tions which are consequent of long-continued intermittent fever, the quantity given for a dose being about 4 of a pagoda weight (20 grs.). Externally, mixed with margosa oil, it is applied to limbs which have become contracted from rheuma- tism. (Mat. Ind., Vol. II., p. 97.) In Bombay the root is mixed with country liquor to make it more intoxicating, and the juice is used to kill maggots in wounds, and is dropped into the ear to cure earache, a practice common to many parts of India, In the Concan the stem is roasted in ashes, and the expressed juice, with honey and borax, given in small doses to promote the expectoration of phlegm; sometimes the juice of Adulsa isadded. For asthma, Mudar flowers, Aghada root, and Gokaran root are steeped in the juice, powdered and given with honey and chebulic myrobalans. Dose about 4 grains. The author of the Makhzan-el-Adwiya, under the name of Zakim (Euphorbia), describes four Indian species, which are probably E. antiquorum, E. neriifolia, E. Nivulia and E. Tirucaili. The milky juice of the first, he says, is mixed with the flour of Cicer arietinum, roasted, and administered in pills as a remedy for gonorrhea. It has a strong purgative action. The juice of the second and third species is heated and dropped into the ear for the cure of earache ; heated with salt it is given as a remedy in whooping cough, asthma, dropsy, leprosy, enlarged ‘spleen, dyspepsia, jaundice, flatulence, colic, calculus, tumours, &c. The fourth species yields a milky juice, having similar properties. Spren- gel identifies H. neriifolia with the -i!o~° (Mahtdéneh) of Ibn Sina, also called Hab-el-mulik, a purgative seed of a reddish 256 EUPHORBIACE. brown colour and like avetch.* The author of the eol& jocosely remarks that the name should be -3lé) 4,4 and says:— Sod G8 Ald po 73) cg! mitiy m4 cg! “it is sufficient as a purgative without the assistance of any other drug.” Ibn Sina describes Mahidaneh as tricoccous and like a large filbert; he says, the name of the plant isShibib. It cannot be LZ. neriifolia, which has seeds no larger than a grain of mustard. In the Dict. of Econ. Prod., published by the Government of India, itis stated, on the authority of Dr. J. H. Thornton, that the juice of E. antiquorum mixed with burnt borax and common salt is used = as an application to painful joints and swellings. Dr. Thornton ‘says:—“The fresh milky juice is a direct irritant both when taken internally and applied externally. Taken in very small quantities, it is a drastic purgative.” EE. trigona, Haworth, the Kattimandu or “‘knife medicine” of the Telugus, so named because it is used for fixing knife blades in their handles, and E. Nivulia, Ham., have similar properties. Description.—Z. neriifolia is a small, fleshy, glabrous tree or shrub, branches jointed, cylindric or obscurely 5-angled, with short, sharp stipular thorns arising from thick tubercles ; leaves deciduous, fleshy, obovate oblong or obovate-acute; involucres in small, stout, dichotomous, short-peduncled cymes from the sinuses, hemispheric, smooth, styles connate high up, undivided, cocci compressed, glabrous; the fruit is tricoccous, but so deeply divided that it has the appearance of three radiating slender follicles. The seed is about the size and shape of a grain of mustard, and of a greyish-brown colour. : #. antiquorum is an erect, fleshy, glabrous tree or shrub, branches terete or obscurely 3—6 angled, branchlets with 3—9 thick sinuate wings, and a pair of sharp stipular thorns in the sinuses; leaves few and small, from the sides of the wing’; fleshy, obovate oblong, tip rounded; involucres 3-nate, forming short-peduncled cymes in the sinuses, styles free, 2-lobed, cocci compressed, glabrous. oes E, Nieulia and EB. trigona are very similar shrubs. pe _* Hab-el-muliik is the seed of Croton Tiglium. A, EUPHORBIACEZ, - ogy Chemical composition.—Henke (Archiv/ d. Pharm., Vol. 224 6), 729—759) has ascertained that the dried juice of Katti- du (EF. Nivculia) contains 35 per cent. of Huphorbon, 25°40 er cent. of resin soluble in ether, 13-70 of resin insoluble in her, 1:50 per cent, of caoutchouc, and the other constituents of mmercial gum euphorbium. The dried juice of H. Tirucalh s also found to be of a similar nature, and to contain 4 per euphorbon, so that we may fairly suppose it, as well as an acid sin, malate of calcium, and caoutchouc, to be a constant constituent of the milky juice of all the plants belonging to the genus. (See next article.) EUPHORBIA RESINIFERA, Berg. Fig.— Jackson, Account of Morocco, t. 6; Berg. et Sch., t. 34d, M—X; Benti. and Trim. 240. Hab.—Morocco. The dried juice (Gum Euphorbium). Vernacular.—Farbiyun, Afarbiyun, Farfiyun (Znd. Bazars). History, Uses, &c.—Euphorbium was known to the ancients. Dioscorides and Pliny both describe its collection on Mount Atlasin Africa, and notice its extreme acridity. Accord- ing to the latter writer, the drug received its name in honour of Euphorbus, Physician to Juba II., King of Mauritania. This monarch, who, after a long reign, died about A.D. 18, was distinguished for his literary attainments, and was the author of several books, which included treatises on opium and euphorbium. The latter work was apparently extant in the time of Pliny. - Euphorbium is mentioned by numerous vale early writers on medicine, as Rufus Ephesius, who probably flourished during the reign of Trajan, by Galen in the 2nd century, and _ by Vindicianus and Oribasius in the 4th. Altius and Paulus _ A®gineta, who lived respectively in the 6th and 7th centuries, . were likewise acquainted with it; and it was also a tothe I1I.—33 F 258 ; HUPHORBIACEZ. Arabian school of medicine. In describing the route from — Aghmat to Fez, El-Bekri of Granada, in 1068, mentioned the numerous plants of A/-Farbiyun growing in the country of the Beni Ouareth, a tribe of the Sanhadja. (Pharmacographia.) Ibn Sina notices the drug under the name of Farbiyun; Haji Zein states that it is called Farbiyun, Afarbiyun, Farfiyun and Taékib, and that the men who collect it have to tie up their faces to prevent the dust entering their mouths, as it would — cause all their teeth to fall out. He says that as soon as it is collected, it is mixed with husked beans to preserve its strength, and that when fresh it is of a yellow colour, translucent, and easily soluble in olive oil; when old it turns,reddish-yellow, the odour is acrid. As regards its medicinal properties, he states that it is a useful application in sciatica, palsy, colic, lumbago, ; and removes phlegmatic humors from the joints and limbs; internally administered it acts as a purgative of bile and phlegm. — However used, it should always be diluted with such substances as oil of roses (fatty extract), bdellium, extractof liquorice, tragacanth or gum arabic; the dose is from one carat to one dang- When given internally to women, it causes abortion, but a pessary containing one grain of euphorbium causes the mouth of the uterus to contract and prevents abortion. Mixed with honey it is used in purulent ophthalmia. Three dirhams is a fatal dose, causing ulceration of the stomach and intestines; the antidotes _ for it are sour milk, the juice of sour pomegranates, and cam- _ phor. _ The author of the Twhfat-el-muminin gives almost a literal lation of what Dioscorides says about euphorbium, and ‘oduce: a great part of Haji Zein’s account of it; he men- : tions its use as a snuff, when diluted with beet juice, in certain affections of the brain, as a dusting powder to remove proud flesh, and as an enema in obstructed menses. In modern medicine, euphorbium is ‘never given internally, but it is still sometimes employed as an ee after having been largely diluted with ili. in amaurosis, deafness, and other chronic irritant is now almo ¢ =e EUPHORBIACEA. 259 Description.—The drug consists of irregular pieces, eldom more than an inch across and mostly smaller, of a dull ellow or brown waxy- -looking substance, among which por- ions of the angular spiny stem of the plant may be met with he substance is brittle and translucent, and has a somewhat mnatic odour; it is extremely acrid, and the dust is | emical composition. —An analysis of selected Leoiuiite free rom extraneous matter by Flickiger (Vierteljahresschrift fur prakt. Pharm., xvii. (1868), 82—102) shows the composition of the drug to be as follows:— Amorphous resin, C!°H'®O? 38 Euphorbon, C'°H?20 22 Mucilage 18 Malates, chiefly of calcium and sodium .. 12 Mineral compounds 10 100 e amorphous resin is readily soluble in cold 70 per cent. petrol. The solution has no acid reaction, but an arsine From the he deprived of the nial resin ethene or pu: leum takes up the Euphorbon, which may be obtained in colour- free from acrid taste, but by repeated erystallizations, and finally boiling in a weak solution of permanganate of potash, may be so far purified as to be entirely tasteless. Euphorbon is insoluble in water; it requires about 60 parts of 80 per cent. alcohol for solution at ordinary temperatures. In boiling alcohol it is freely soluble, also in ether, benzole, amylic alcohol, _ chloroform, acetone or glacial acetic acid. odour. By dry distillation a brownish oily liquid is obtained, Euphorbon melts at 113 to 116° C. without emitting any a. 260 EUPHORBIACEZ. which requires further examination. If euphorbon dissolved in alcohol is allowed to form a thin film in a porcelain capsule, and is then moistened with a little concentrated sulphuric acid, a fine violet hue is produced in contact with strong nitric acid ‘slowly added by means of a glass rod. ‘The same reaction 1s ‘displayed by lactucerin, to which in its general characters euphorbon is closely allied. If a few drops of an alcoholic solution of euphorbon are allowed to dry on a piece of filtering paper, and then touched with adrop of nitric acid, a blue colour will be developed, Pure euphorbon, according to Henke, melts at 67° to 68°; its composition was found to be C*°H*O. Its rotatory pow dissolved in chloroform was [a]p= +15°°88. Hesse assigns be euphorbon the formula C’°H?*O. The mucilage of euphorbium is precipitated by neutral acetate of lead, as well as silicate or borate of sodium, it there- fore does not agree with gum arabic. a If an aqueous extract of euphorbium is mixed with spirit of wine, and the liquid evaporated, the residual matter assumes a somewhat crystalline appearance, and exhibits the reactions — of Malic Acid. Subjected to dry distillation, white scales and acicular crystals of Maleic and Fumarie acids, produced by the ‘decomposition of the malic acid, are sublimed into the neck of the retort. (Pharmacographia, 2nd Ed., p. 560.) Toxicology.—Kuphorbium causes the eyes to weep and grow ed, the nose to run with watery and even bloody mucus, and saliva to flow abundantly from the mouth. To prevent ‘these effects, says Pereira, some drug-grinders employ masks with gilass-eyes, others apply a wet sponge to the : nose and face; while others cover the face with rape. I was informed, he adds, of 7% ‘ly insane by it, and ¥ EUPHORBIACEA. 261 rrew suddently delirious, and presently became insensible and fell in a fit. His face was red and swollen, his pulse frequent and full, and his skin very hot. On being bled, his conscious ess returned and he complained of great neadache. 3 _ Under Euphorbiaceex, Norman Chevers, quoting Dr. H. "Cleghorn of Madras, says:—‘‘There are several species of Euphorbia, as the E. neriifolia, antiquorum, acaulis, and others ich abound ina milky juice. This produces a blister when rubbed on the integuments, and serious inflammation if dropped ‘into the eye. Several cases have happened within my _ knowledge, where the sight has been endangered frem this ~-eause.” (Indian Med. Jurisprudence.) Other species of Euphorbia found in India, and occasionally used medicinally, are E, helioscopia, Linn., the Sun Spurge, anative of Afghanistan and the Punjab, E. hypericifolia, Linn., and E. Royleana, Boiss., a native of the outer Himalaya. E. helioscopia is used as a hydragogue cathartic, and the juice is applied to remove warts. Dr. Baudry (Bull. Med. du Nord, 1887) has reported a case of severe ulceration esis p from the application of a poultice of the bruised plant. E. hypericifolia has not unfrequently been mistaken for E. pilulifera, but may be distinguished readily by its not having - the hairy stem of the latter plant: In Réunion it is used as an astringent in dysentery under the name of Herbe Jean-Robert. PHYLLANTHUS EMBLICA, Linn. Fig.— Brand, For. Fl., ¢. 52; Bedd. Fi. Syiv., t. 258; A. Juss. Tent. Euphorb., t. 5, f. 15; Rheede, Hort. Mal. i., t. 38. Emblic myrobalan (£ng.), Emblic officinal (/r.). Hab.—Throughout tropical India. The fruit, bark, and flowers. Vernacular.—Anvula (Hind.), Amlaki ( (Beng.), Avala, Aval- kéthi (Mar.), Nelli-kai, Toppi (Zam.), Nelli-kaya, Usirike-kay; (Tel.), Nelli-kaya (Mai), Nelli-kayi (Can.), Ambala (Guz.). 262 EUPHORBIACE. History, Uses, &c.—The fruit of this tree is the Dhitriphala, Amritaphala, Amalaka or Sriphala of the Nighantas, and is described as having all the properties of the chebulic myrobalan. It is used both fresh and dried ; in the former condition it is considered to be refrigerant, diuretic and laxative ; in the latter, astringent. It is pickled by the natives, and, on account of a peculiar flavour which it imparts, some of the forest tribes eat it before drinking water. A sherbet of the fruit, sweetened with sugar or honey, is a favourite cooling drink for sick people ; it is said to be diuretic. A country-side prescription for biliousness in the Concan is Avala, 4 massas, to be soaked all night in water, and in the morning be pounded and mixed with a quarter seer of milk and flavoured with sugar and cumin. Emblic myrobalans are a0 ingredient in many compound preparations described in Sanskrit works. A selection of these prescriptions will be found in Dutt’s Hindu Materia Medica; the following, translated from Chakradatta, may be taken as an example :— “ Dhatri lauha.—Take of powdered Emblic myrobalans 64 tolas, prepared iron 32 tolés, liquorice powder 16 tol4s, mix them together, and soak in the juice of Tinospora cordifolia seven times successively. This preparation is given in jaundice, anzmia and dyspepsia, in doses of from 20 to 40 grains.” Mahometan physicians esteem this myrobalan equally with the Hindus; they describe it as astringent, refrigerant, cardia- cal, and a purifier of the humors of the body. It is much prescribed by them in fluxes, and is also applied externally on _ account of its cooling and astringent properties. The Arabic name is Amlaj, and the Persian Amala. Ainslie states that the flowers, which have an odour resembling that of lemon peel, are supposed by the Vytians to have virtues of a cooling and aperient nature, and are prescribed in conjunction with other articles in the form of an electuary. (Mat. Ind. ii 244.) fn the © veils Tila at. Ind., ii., p. 2* of Dr. 28. Ross, that the root by. oo ae yields an astringent extract equal to Seach Godk od eaicihel EBUPHORBIACEH. 263 poses and in the arts; the chips of the wood or small oches thrown into impure or muddy water, according to the e authority, clear it effectually. In the Concan the juice of © fresh bark, with honey and turmeric, is given in gonorrhea. Description.— Fresh Emblic myrobalans are globular, , smooth, six-striated, of a yellowish-green colour, and imes as large as a walnut; they contain an obovate obtusely cular, 3-celled nut, each cell of which contains two triangu- The taste of the pulp is acid, astringent, and some- at acrid. The dried fruit is the size of a cob nut, sub- gonal, wrinkled, of a grey-black colour if it has been ollected when immature, but yellowish- -brown if mature; the latter upon pressure breaks up into six parts, each of which consists of a section of the pulp and nut, and contains one triangular brown seed. Chemical composition—The pulpy portion of the fruit dried ee and freed from the nuts, had the following composi- ~ Ether extract (gallic acid, &c.) ......... ee ae Alcoholic ,, (tannin, sugar, Go.) Wiriesws 36°10 Aqueous ,, (gum, &c.) 435 ARE Soda jy~ (albumen, 407) i acheniens 13°08 Crude cellulose 17°80 Mineral matter 4:12 Moisture and lose... cis. cies ce cui OSS 100-00 The acidity of the fruit was found to be equal to 9°6 per cent., calculated as acetic acid. The amount of tannic acid, estimated with acetete of lead solution, was 35 per cent., and 10’ per cent. of glucose was estimated by means of Fehling’s solu- ion on an infusion of the pulp after the removal of the tannin, Lowe considers this tannin to be identical with the ae mnie acid of Divi-divi. 264 EUPHORBIACEZ. Commerce.—Two kinds of Avala are found in commerce, one entire, and the other cut up, and the nut removed. The ~ fruit is collected in many parts of India. Value, about Rs, 32 per candy of 7 ewts. PHYLLANTHUS RETICULATUS, Pair. Fig.—A. Juss. Tent. Euphorb. 19, t. 4, f.1; Wight Ie, t. 1899; Burm, Thes. Zeyl., t. 88. Hab.—Throughout tropical India. The leaves and bark. Vernacular.—Pénjoli (Hind.), Pélagtda (Tel.), Pilavayt (Tam.), Panktishi (Beng.), Pavana, Puvana (Mar.), Kamobi (Sind.), Datwan (Guz.), Katu-nirdri (Ma/.). History, Uses, &c.—Ainslie (Mat. Ind., ii., 223) le Krishna-kémboji as the Sanskrit name of this plant. i 3 “coming from Kamboj,” is applied in that language to severm® plants, but none of them have been identified with P. reticulatus, 4 nor does it appear to be mentioned in the Nighantas under | other name. The leaves and bark are used as a diuretie and cooling medicine and as an alterative. Ainslie says :— = bark, as it appears in the Indian bazars, is commonly = pieces about a foot long, and as thick as the wrist, of c dark colour outside,.and of a faint sweetish taste; ce considered as alterative and attenuant, and is prescribed 3 decoction, in the quantity of 4 ounces or more twice daily. the Concan the juice of the leaves is made into a pill with ~~ phorand cubebs, and dissolved in the mouth asa remedy for bleed ing from the gums; it is also, along with the juice of — erative plants, reduced toa thin extract, and made into? vith aromatics. This pill is given twice a day, rubbed dow” \ alterative in heat of blood. __ Deseription.—Shrubby, climbing, primary branches : twiggy ; young shoots pubescent ; floriferous branchlets ese d leaven. av sobtus , bifarious; flowers axillary, aggres® i saree Ke usually one female; male flowers purplish ; le. This plant is common a ere it is found in the forests * i bs ay Spas aoe ace ae Oily he ears EUPHORBIACEZ. 265 great size, climbing to the tops of the highest trees. (Bomb. _ Flora.) The flowers have a peculiar and disagreeable smell. The bark is dark-brown externally, and thickly studded with little elliptic warty rings; beneath the suber is a deposit of chlorophyll, bit the substance of the bark is of a dull-red colour. Taste sweet and astringent, Microscopically there is little to remark beyond masses of deep purple pigmentary matter and groups of large stone cells. Chemical composition.—The leaves contained a tannic acid similar to that separated from other species of this genus, but no alkaloid. A crystalline principle soluble in ether was removed from the aqueous solution of the alcoholic extract; it gave a yellowish-brown colour with sulphuric acid, a brown colour with Fréhde’s reagent, anda yellow solution with alkalies, The powdered air-dried leaves afforded 7°83 per cent. of ash, and when mixed with water became very mucilaginous, and it was very difficult to filter this mixture through paper. Phyllanthus madraspatensis, Linn., Wight Ic., 1895, f. 3, yields the Kanocha seed of the bazars. The seeds are polished, triangular, of a grey colour, prettily marked with delicate dark-brown lines like basket-work; length 74 of an inch; breadth somewhat less; one side is arched, the other presents. two sloping surfaces united to form a longitudinal ridge, at the pointed end is asmall scar marking the attachment to the ovary; the testa is hard and brittle. When soaked in water they immediately become thickly coated with a semi- opaque mucilage ; the kernel is oily and has a sweet nutty taste; i the sceds are used medicinally on account of the mucilage which they afford. PHYLLANTHUS NIRURIJ, Linn. Fig.— Wight Ic., t. 1894; Rheede, Hort. Mal. tig 8. 1De PHYLLANTHUS URINARIA, Linn. Fig.— Wight Ic., t. 1895, f. 4; Rheede, Hort. Mai. z., t. 16. Hab.—Throughout India. The herbs. saiiaks IIL—s4 kA 266 EUPHORBIACE. Vernacular,—Bhumi-a’nvala (Hind.), Bhui-amla (Beng.), Bhui-a’vala (Mar.), Kizhkay-nelli (Zam.), Nelli-usirika (Tei), Kizha-nelli (Mal.), Kiranelli-gida (Can.), Bhui-amali (Gus), P. urinaria is distinguished by the addition of the adjective red to the above names. History, Uses, &c.—These plants are common weeds which appear in the cold season. They are called in Sanskrit Témra-yvalli (P. urinaria) and Bhumy-dmali (P. Nirwri), and bear among other synonyms those of Tamalika, Bhu-dhétri, and Bahu-pattra, “having many leaves.’”’ Hindu physicians consi- der them to be deobstruent, diuretic, astringent and cooling, an prescribe the dried plant in powder or decoction in jaundice. The dose of the powder is about a teaspoonful. Mir Muham- mad Husain in the Makhzan states that the milky juice As -a good application to offensive sores, and that a poultice of the leaves with salt cures scabby affections of the skin; without salt it may be applied to bruises, &c. From Ainslie we learn that these two plants are the Herba meroris alba and rubra of Rumphius, and that an infusion of the leaves of P. Nu" with fenugreek seed is considered a valuable remedy in chronic dysentery, also that the leaves are a good stomachic bitter. — In Bombay P. Niruriis used as a diuretic in gonorrhea and acidity of the urine. The dose is 2 tolds of the juice with 2 tolés of ghi twice a-day. The root rubbed down with rice-water given in the Concan as a remedy for menorrhagia. Dr. A. J. Amadeo states that the plant is known as Yerba de quininic at Porto-Rico, and is used in decoction in inter- _ mittent fevers ; he thinks favourably of it, and uses a tincture in 2-drachm doses; it acts as a gentle purgative, and: 38 especially useful when the liver and spleen are infarcted. It is diuretic, Description.—P. Niruri: Annual, erect-branched; branches herbaceous, ascending ; floriferous branchlets fili- pi sare elliptic, mucronate, entire, glabrous ; male on mae Mowers in separate axils, male on the lower On0S> dehiscence of anthers transverse ;. glands in the fe EUPHORBIACEZ. 267 nd trifid; capsule globose; two smooth seeds in each cell; eds triangular. P.urinaria:; Root generally annual, though in some soils biennial and even perennial. Stem erect, striated, of a pale reddish colour; branches several, ascending, striated from the insertions of the stipules; leaves scattered, spreading, pinnate, from one to two inches long, th Mpa ; leaflets nate, linear oblong, entire, smooth, ¢ of an inch long, and broad ; petioles compressed, somewhat triangular ; stipules of the petioles 3-fold, acute, membranaceous, those of the leaflets _ two, lateral; male flowers, exterior leaflets axillary, 2 to 3, subsessile ; Billy, nectary and stamens as in P, Niruri; female flowers, lower leaflet axillary, solitary, sessile ; calyx and nec- tary as in the male; capsules scabrous, 3-celled, 6-valved; _ seeds, two in each cell, transversely striated on the outside. It is immediately distivpulahed from P. Niruri by its sessile flowers and scabrous eapatiles: (Rowb.) _ Ohemical composition.—The alcoholic extract from the whole plant was mixed with water acidulated with sulphuric acid, and agitated first with petroleum ether, then with ether, and ly rendered alkaline and reagitated with ether. The petroleum ether extract was dark-coloured, and soft, with a tea-like odour, and extremely and persistently bitter. It was mixed with 8 per cent. caustic soda solution and reagi- tated with petroleum ether, which removed the bitter principle contaminated with traces of oil and colouring matter. This extract gave the euphorbon colour reaction when treated with sulphuric and nitric acids. For the bitter neutral principle, we propose the name of pseudochi atin. The acid ether extract contained green colouring matter, and was partly soluble in water with acid reaction, the solution giving a dirty bluish-green coloration with ferric chloride, slightly precipitating gelatine, but affording no reaction with _ cyanide of potassium, The alkaline ether extract contained an alkaloidal principle, which, after purification, was obtained in white feathery erystals 268 - RUPHORBIACE® ‘without any special taste. With Frohde’s reagent it gave a light yellowish-red coloration, changing to blue on heating; with concentrated nitric acid, yellowish. No reaction with dichromate of potassium and sulphuric acid. BRIDELIA RETUSA, Spreng. ; Fig.—Baill. Etudes Gen. Euphorb., t. 25, f. 25—34; Bedd, Fil. Sylv., t. 260 ; Rheede, Hort. Mal. ii., t. 16, Hab,—Throughout the hotter parts of India. The bark. Vernacular.--Khéja, Kharaka, Lamkana (Hind.), Mullv- vengai (Zam.), Dudhi-maddi, Kora-maddi (TZe/.), A’séna, Phattar-phoda, Paléhasan, Kéntehasan, Hasdni (Mar.), A’sdna, Gurige (Can,). History, Uses, &c.—The astringent properties of the bark of this tree appear to be well known throughout India, a8 it is in general use for tanning leather. The wood is also much used, on account of its durability under water, for making well-curbs. In Western India the bark has a reputation as a lithontriptic, and is in general use as an astringent medicine. The tree is with or without thorns, according to situation and soil; the natives of Western India consider the thornless tree to be a distinct species, and call it Pdlehasan, whilst the thorn-bearing tree is known to them as Kéntehasan. When wounded, the bark exudes a blood-red juice, which stains the hands, and is very astringent. EUPHORBIACE. 269° Chemical composition—The bark afforded 41°7 per cent. of water extract, containing 39-9 parts of tannic acid. The tannic acid gave a greyish-green precipitate with plumbic acetate, and a blue-black colour with ferric chloride. The air- dried bark left 7°35 per cent. of ash on incineration. Although this is one of the most astringent barks in India, it does not appear to be known to, or used by, Europeans in the arts. CLEISTANTHUS COLLINUS, Benth. Fig.—Beddome, Foresters’ Man., 203, t. 23, 7. 9 ; Roxb. Cor. Pleii., 37, ¢. 169. Syns.: Lebidieropsis orbicularis, Mull-Arg., Cluytia collina, Roxb. Hab.—Dry hills, in various parts of India, from Simla tt Behar. Deccan Peninsula. Vernacular.—Oduvan, Woodacha, Nachuta (Tam.), Kadishe (Te/.)., Kodasigina, Bodadaraga (Can.). History, Uses, &c.—Under the name of Andrachne Cadishaw, Ainslie describes the poisonous properties of the nut of this tree, called Wodoowunghai. He says:—‘ About one pagoda weight, pounded, the Tamools believe to be sufficient to kill a man; the leaves and roots of the plant are also considered poisonous; the first, which no animal will touch, is, in conjunction with Kadukai (chebulic myrobalans), supposed to be a good application to foul ulcers. (Mat. Ind., ii., 487.) Roxburgh remarks:—“ The bark or outer crust of the capsule is reported to be exceedingly poisonous.” (F7. Ind., iii., 733.) Description.—Capsule 3 of an inch in diameter, sessile, woody, rounded-3-gonous, top not lobed, dark-brown, shining and wrinkled when dry. Seeds 4 of an inch in diameter, globose, chestnut-brown; albumen scanty. Chemical composition.—The active principle of the plant does not appear to be an alkaloid, but, though its chemical nature has not yet been fully investigated, Mr. Newman, Assist. Chemical Examiner, Madras, has discovered that it gives a purple reaction with sulphuric acid, which disappears on oxidising with 270 EUPHORBIACEZ. alkaline dichromate, and with nitric acid a blue colour changing to green; these tests serve to identify it with some degree of probability. An extract of the leaves and fruit acts as a violent gastro-intestinal irritant. (Report, Madras Chem. Examiner; 1885.) Toxicology.—The Madras Chemical Examiner reported in 1885 that the poison had been found in two cases from South Arcot. “In one case a man being detected in an intrigue with his mother-in-law, her relations threatened to excommunicate her; whereupon both are supposed to have taken this poison and to have died very soon—from half an hour to an hour—after taking it. Both vomited. In the second case vomiting and purging were followed by recovery.” In 1886 .the same Chemical Examiner reported that the expressed juice of certain leaves (of Oduvan), the residue of which was sent for examination mixed with common salt, was supposed to have been taken by aman to cure itch. He suffered from vomiting and died ina few hours. In 1887 Odwvan was found, in a case from South Canara, in the stomach of a woman who poisoned herself when her husband was dying. She was suddenly seized with vomiting and died rapidly. In 1889 a woman was suspect of attempting suicide by poison; the leaves found in her possession were identified as those of this plant. In 1890 @ pregnant woman died with symptoms of gastro-intestinal irritation, after taking an abortifacient ; from her stomach was extracted a non-alkaloidal poison which gave reactions similar to those obtained from the extract of this plant. _ ‘The bark of Flueggia Leucopyrus, Willd., Wight Ie. ¢. 1875, ashrab of the Punjab Plain, the Deccan Peninsula, and Ceylon, is used both in Madras and Bombay as a fish-poiso”- The Sweet, white berries do not appear to have any injurious properties, as they are eaten by children, who call them adh thenag) The juice of the leaves is used to destroy worms 12 . Ohenieat: composition.—The bark contains 10 per cent. of a a ae Siving a-violet-black colour with ferric chloride, EUPHORBIACEZ. 271 * and the mixture becomes red on the addition of ammonia. An alkaloid is also present, giving a purplish-red colour, afterwards turning to green, with Fréhde’s reagent, and a violet colour with strong sulphuric acid and permanganate of potassium. The alkaloid is soluble in excess of alkalies, The infusion was somewhat frothy, but no sapogenin could be isolated from it after boiling with acid. — The bark of Flueggia microcarpa, Blume, Wight Ic., t. 1994, supplied by Mr. Hollingsworth as one of the South Indian fish-poisons, was in thin papery light-brown strips, and the powder had no odour and very little taste. Air-dried, it afforded 11°4 per cent. of mineral matter, and contained 8°9 per cent. of a tannin, giving a blue-black colour with ferric salts. The aqueous solution of the alcoholic extract furnished an alkaloidal principle similar in its reactions to that obtained from the bark of F. Leucopyrus. Breynia rhamnoides, Mill-Arg., Wight. Ic., t. 1898, is a shrub or small tree of tropical India. According to Ainslie, it was brought to Dr. F. Hamilton, while in Behar, as a medicine of some note; the dried leaves are smoked like tobacco, in cases in which the uvula and tonsils are swelled. The bark is astringent. Description.—Shrubby ; young shoots angular; leaves alternate, short-petioled, spreading, broad-oval ; exterior ones largest, below whitish, entire, half to three-quarters of an inch long; male flowers racemed from the lower axils ; female flowers in the upper axils, solitary, short-peduncled, drooping; capsule size of a pea. The nuts of Putranjiva Roxburghii, Wa//., in Sanskrit Putra-jiva or Putram-jiva, ‘that which makes the child live,” are hung round the necks of children to keep them in good health. They are mentioned in the Nighantas as being also Garbha-kara, “productive of impregnation,” and medicinal pro- perties are attributed to them. The hard wrinkled nuts are generally worn only as a charm, but are sometimes given inter- __ nally in colds on account of their supposed heating properties; 272 _ HUPHORBIACE Z#. they are called Jivapota in Hindi, Kurupale in Tamil, Kabra- juvi in Telugu, Pongalam in Maliyali, and Jivanputra ia Mara thi. = JATROPHA GLANDULIFERA, Roxwb. Hab.—Deccan Peninsula, Bengal, Northern Circars, and sparingly elsewhere. The juice, root, and oil. Vernacular.—Underbibi, Rén-erandi, Tadki-crandi (Iu), Lal-bherenda (Hind., Beng.), U’dalai (Tam.), Nela-amudamu ( Tei.). History, Uses, &c.—This plant appears to have been introduced into India, but it is not known from whence. Graham, in his Catalogue of Bombay Plants, published in 1839, says that in his time it was only to be found at Punderpore in the Deccan (a place much frequented by pilgrims, who come to visit the temple of Vithoba). There is a fabulous legend that it suddenly made its appearance at this place. The following is the story, for which we are indebted to Dr. Shantaram V. Kuntak of Punderpore :—“ A certain cultivator was sowing his field on the 10th day of Ashadh, during the Ashédhi fair; whilst thus engaged he was accosted by numbers of pilgetons who were passing by his field, on their way out of the town, to meet the palanquins of Dnydnoba, Nimdeo and Tukéram, which are brought to Punderpore at this season from Paithan, Alandi, and Dehu. All the pilgrims asked him what he was sowing, until the man got tired of answering their questions ; in a short time another pilgrim came up and asked the same question, —the man, » vexed beyond endurance, answered that he was sowing 4 (membrom virile). It is said that this last pilgrim was the god Vithoba in disguise, who was going to meet the palanquins of his wen ee and — » annoyed at the cultivator’s answer, he g, ‘ As you sow, so may you reap.’ So when harvest time came, instead of the usual crop, the whole field was covered — s igs ‘thick-stemmed plant.” Until within | EUPHORBIAOER. : 273 the last few years the field was called after the strange crop - which it bore. It is now cultivated by a Mahometan, an produces a regular crop, but the Jatropha has not been entirely extirpated. Since Graham’s time the plant has spread rapidly, and may be seen on waste ground in most parts of the island of Bombay, probably introduced along with the Castor seed of commerce. An oil is prepared from the seeds by roasting them in a perforated earthen vessel, fitted upon another vessel, - into which, when the whole apparatus is heated in a pit filled _ with burning cowdung fuel, the oil drops. This oil is valued as an application to chronic ulcerations, sinuses, ringworm, &e. The root brayed with water is given to children suffering from _ abdominal enlargement; it purges, and is said to reduce __ glandular swellings. The juice of the plant is used in various parts of India as an escharotic to remove films from the eyes ; it is greenish and viscid. The expressed oil of the seeds is yellow, has a specific gravity of 0-963, and solidifies at 5°C. (J. Lepine, Jour. Phar. [31, xl., 16.) | ; Description.—A small shrub, remarkable for the shin- ing reddish-brown colour of its young foliage. The leaves are palmate, 3 to 5-cleft, panicles terminal, short, few-flowered ; flowers small and red. The young branches and petioles of the leaves are thickly studded with sticky red glandular hairs. The capsules are 3-celled and 3-seeded, with an outer adherent fleshy epicarp, which dries up as the fruit ripens; when this takes place, the three triangular woody cells of which it is composed divide into six pieces suddenly with a sharp report, and the seeds are projected to a considerable distance; it is, therefore, necessary to gather the fruit before it is quite ripe and dry in a covered place. The seeds, including the strophiole, are three-tenths of an inch long and two-tenths broad ; they are of a grey colour with two brown stripes on the dorsum, which is convex, the underside has two flat surfaces, divided by a central ridge. The kernel is without smell, and very oily ; it has a sweet, nutty taste. Reena pee x « Chemical composition.-—See Jatropha Curcas. IIL,—35 274 HEUPHORBIACEZ. Jatropha nana, Dailzei/, Kirkundi (Mar.), is a rare plant, found in waste, stony places near Poona. The juice is employed as a counter-irritant in the same manner as that of J. glandulifera. Description.—A shrub 1 to 14 foot high, all smooth ; root tuberous, woody ; root-bark thick and full of milky juice; stem round, smooth, very little branched ; branches erect; leaves large for the size of the plant, sessile or shortly petioled, broadly ovate, entire or trilobate ; lobes obtuse, central much the largest, 4 to 6 inches long and broad, pale beneath, 3-nerved, flowers panicled, terminal, few, 3 to 5 on each division ; stipules minute; flower solitary, pedicelled, subtended by a subulate bract half its length ; calyx leaves six, small, subulate; fruit obovoid, flattened at the top, slightly six-suleated, as large asa nut. (Da/zeli.) JATROPHA CURCAS, Linn. Fig. — Jacq. Hort. Vind. iti., t. 63; A. Juss. Tent. Euphorbe ‘t. 11, p. 84 A. Physic Nut (Eng.), Medicinicr (F.). - Hab,—Throughout India and Ceylon, naturalized. Vernacular .—Baghrénda, Bagh-bherenda (Hind., Beng-); Moghli-erandi, Jepal (Mar.), Galamark (Goa), K4ttAmanakku (Zam.), Pépdlam (TZel.), Kétté-vanakka (Mai.), Bettada-haralu (Can.), Jangli-arandi (Guz.). History, Uses, &c.—This tree, introduced from AL ler ica, is called by recent Sanskrit writers Kanana- eranda. . seeds are sometimes used as a purgative and alterative by Ein oo but on account of their uncertain action ( ieation to iteh, herpes, chronic i octal and <— ma states that the blacks of Rio — “the oil with the ashes of the Papaya, and use 1 to heal the wounds caused by circumcision. | ubefacient and discutient, and a the secretion of milk in ee Saleen, Tey sea a ae v eee Pe EUPHORBIACE. 95 yomen. ‘The viscid juice which flows from the stem upon ncision is painted over cuts and wounds'to check bleeding and mote healing ; this it does by forming a thin film when dry ike that produced by collodion. The author of the Makhzan 1so notices this use of the juice, and calls the plant Baghréndeh. . Udoy Chund Dutt notices the haemostatic properties of the , and Dr. Evers has injected a drachm of it into a varicose rism. He says :— ‘ The result was astonishing ; in twenty tes time the pulsation was so faint that no non-professional son could have detected it; and by evening all pulsation ceased, and a good firm olct had been produced. No ill- : effects resulted fron the injection.” J. Curcas is said to have ‘been introduced from Brazil by the Portuguese ; it is now quite naturalized in many parts of India, and is a common hedge- plant in the Concans. The oil is used for burning. The juice, when dried in the sun, forms a bright reddish-brown, brittle ubstance like shell-lac, which may Ae be put to some useful he God rubbed with Castor oil are used by the natives as a J eae oil was formerly employed as a purgative by Hhire- pean physicians, under the names of Olewm Ricint majoris and Oleum infernale. At the present time it is much used for burn- ing and for soap-making; also for adulterating olive oil, and seemingly for making ni 8 oil. (#. WM. Horn, Zeit. Anal. ~Chem., xxvii., 163—165. Description.—The young rootsare soft, fleshy, and taper- ing, with a whity-brown sealy epidermis, and a few thin rootlets, bark yellowish-white internally, with a peculiar perfume like tuberose when freshly removed ; wood white and very soft. On — section the bark is seen to contain oil globules and very numer- oe ous conglomerate raphides; the vascular system | is full o a 276 EUPHORBIACE 2. yellowish viscid secretion; the wood is loaded with starch, The taste of the bark is acrid. The fruit is ovoid, 6-striated, tricoccous and fleshy ; when ripe it is of a pale greenish-yellow; as it gradually dries up it becomes black and partially dehiscent. There is one seed in each cell. The seeds (Pignons d’Inde) are of the same shape as Castor seeds, 3 of an inch long and rather less than half an inch broad ; the dorsal surface is arched and marked by a hardly perceptible ridge about the middle; the ventral surface has a well-marked ridge. At one end of the seed is a white scar. The testa is of a dull black and irregularly fissured all over, the fissures are yellowish. The kernel is enclosed in a thin, white membranous covering like that of the Castor seed. The cotyledons are foliaceous, the radicle short and thick, the _ albumen copious and oily. Chemical composition.—The kernels of the seeds of J. Cwreas were found by Arnaudon and Ubaldini ( Kopp’s Jahresber., 1858) to contain 7:2 per cent. water, 37:5 oil, 55°3 sugar, starch, bumin, casein, and inorganic matters. The kernels yielded 4°8 per cent. ash, and 4:2 per cent. nitrogen; the kernels and husks together 6 per cent. ash, and 2-9 per cent. nitrogen. The oil yielded by saponification, glycerine and an acid, which, well as the unsaponified oil, produced caprylic alcohol by distillation with hydrate of potassium. Bouis had previously separated from it a liquid and solid fatty acid, and named the latter Isoacetic Acid, C'5H5°O%. Cadet de Gassicourt (1824) found in the seeds an acrid resin. __ F.M, Horn (Zeit. Anal. Chem., xxvii., 163—165) states that the oil begins to crystallize at 9°, and is completely solid at 0°, at 15° its Sp- gr. is 09192. It differs from Castor oil in its very sparing solubility in alcohol. It appears to saponily . readily in the cold, but in reality forms only acid soaps; __ for complete saponification heat is required, and solid potash acts better than solution, _ ‘The fluid oleic acid obta; : doubtless be ‘rogurded as ricingleioaeidy OS® ™Y EUP AQE AA 277 | According to Dr. H. Stillmark, the seeds contain mess the onous principle of Castor seeds (see Ricinus). Toxicology.—Christison (Poisons, p. 591) found from 12 to 15 drops to have generally the same effect as an ounce of Castor oil. Stillé and Maisch remark that it is more like Croton oil in its action. The acrid emetic principle resides chiefly in the mbryo. It is stated that if the embryo is wholly removed, - or five of the seeds may be used as a purgative without producing either vomiting or griping. This opinion is sup- ted by experiments upon dogs. A number of cases have occurred of poisoning by eating the seeds entire. In one case, a man who had eaten five of them soon complained of burning in the mouth and throat, and the whole abdomen felt distended andsore. Inafew minutes vomiting occurred, and was repeated five times in the course of an hour, accompanied with active purging. The pain continued; the patient complained of _ feeling hot and giddy ; ; he then became delirious, and afterwards insensible. On regaining consciousness several hours later his face was pale, his hands cool, the pulse 110 and weak. He recovere | ae cases of accidental poisoning by the seeds have been = recorded in India, and Chevers mentions one in which, in addition to the usual symptoms, muscular twitchings, deafness, impairment of sight, and loss of memory were observed. Jatropha multifida, Linn., Salisb. Hort. Paradis., t. 91, the Medicinier d’Espagne of the French, and Coral tree of the English, is a common ornamental shrub in Indian gardens; it is not used medicinally, and only requires a brief notice on account of its seeds, which are powerfully purgative and emetic, sometimes giving rise to accidents when eaten by children. The plant is easily recognised by its multifid leaves and beautiful, red coral-like panicles of flowers. The fruit is bright-yellow when ripe, as large as a walnut, six-angled and ~ _three-celled, each cell contains a scabrous black seed resembling that of J. Curcas, We have found limejuice and stimulants to be the best remedies in cases of poisoning by the seeds. The 278 _ EUPHORBIACEZ. plant appears te have been introduced by the Portuguese 4 from Brazil, where the oil of the seeds is known as Pinhoen oil, i and is used as an emetic. / = At Martinique it is called Zeca pays, on account of its being used in a similar manner ; one seed acts as an emeto-cathartic, Corre and Lejanne state that the Creole women used to prepare an “Orange purgative”’ by macerating an orange in the oil for a month, and then drying it; this orange, when rubbed in the -hands and smelt, was believed to act as a purgative. According to Soubeiran, the oil of these seeds is very similar to, if not identical with, that of J. Curcas. . Towicology.—Cases of accidental poisoning by the fruits have been recorded in India, chiefly among children who have heen attracted by their temptiag colour. The symptoms have been similar to those produced by J. Curcas. = ia ALEURITES MOLUCCANA, Willd. — Pig.—Lamk. Wi, ¢. 791; A. Juss. Tent. Buphorb., t. 12; Rumph. Amb. ii., t. 58. Candleberry tree (Zng.), Aleurit des Mollugues (Fr). Hab,—Pacific Islands. Cultivated in India. The oil- Vernacular.—Jangli-akhrot (Hind.), Rén-akhrot, J aphala (Mar.), Jangli-akhroda (@uz.), Nattu-akhrotu (Tam., Tel.), Nat-akrodu (Can.). History, Uses, &c.—Rumphius (iii., 12) states that the ese and Macassars make candles of the seeds of this al ided and mixed with cocoanut or cotton seeds, or simply seeds are known as Indian walnuts. Whet arge proportion of oil, used as a drymg as country walnut oil, bankoul-nut lon it is called Kekuni oil, and EUPHORBIACEE. © | 279 s. bout 10,000 gallons are annually produded: It has been orted into Europe for soap-making, but not to any msiderable extent, and fetches about £20 per imperial ton. The oil is stated to possess powerful desiccative properties. The cake, after the oil has been expressed, is esteemed a manure. The root of the tree affords a brown dye, ch is used by the Sandwich Islanders for their native hs. In India the oil is used as a dressing for ulcers ; its icinal properties were examined by Dr. O. Rorke bina: ade rap., 1899, p. 117), who found that in doses varying from to 2 ounces it acted as a mild and sure purgative, producing in from three to six hours, after ingestion, free bilious evacuations, its operation being unattended either by nausea, colic or other ill-effects. (Phar. of India, p. 203.) From more recent experi- ments it appears that half an ounce of the oil is a sufficient _ aperient. MM. Corre and Lejanne (Résumé de le Mat. Med. et _ Tox. Coioniale) remark :—“ There is no doubt that the properties of this oil differ when the oil is prepared in different ways.” When cold drawn from the fresh nuts, Heckel, who used it at the Military Hospital at Nouméa, found that it was only purgative in 80 gram doses, that is to say, it simply acted as a fatty oil ; he found that the drastic resinous constituents remained the oil-cake. M. Jugant, at Nosi-Bé, found that the oil tracted by the hot process acted freely as a purgative in 40 gram doses. Many observations were made in the Military from 1 to 3} hours. Dr. Grasourdy considers the oil to equal castor oil in purgative properties. The oil, if intended to be used as a purgative, should be extracted by pressure between Description.—A tree of considerable magnitude, attain- ing the height of 30 to 40 fect. The leaves are alternate, four to eight inches long, stalked and without stipules, either See _ the young parts covered with a whitish starry pubescence The flowers are small and white, growing in clusters _ of the branches, the —_ and females tog oval-acute and entire, or fiom three to five-lobed, and like all a 280 EUP ACER same cluster, the former being the most numerous. The fruit is 2-celled, fleshy, roundish, and, when ripe, of an olive colour, its greatest diameter about 24 inches; each cell contains one ovoid somewhat flattened nut, the shell of which is very hard and thick ; the kernel is conform to the nut, white and oily. Chemical composition.—The nuts have been examined by Nallino (Gaz. Chim. Ital., ii., 257), who found the average weight of the husks to be 6°5 grams, of the almonds 3°3 grams. Composition of husks: water, 3°71; organic matter, 89°90; mineral matter, 6°39. Composition of almonds: water, 5°28; fat (extracted by carbon sulphide), 62°97 ; cellulose and other organic matters, 28°99; mineral matter, 2°79. Composition of the ash of the almond: lime, 18°69; magnesia, 6°01; potash, 11°33; phosphoric anhydride, 29°30. The fatty matter _ extracted from the almonds by carbon sulphide at ordinary temperatures forms a transparent, amber-yellow, syrupy liquid. en cooled to —10°, it becomes viscous, but neither loses its transparency nor changes colour. According to Brannt, the oil has a specific gravity of 1:940 at 59°F. It consists of an olein resembling linolein, besides myristin, palmatin and stearin. The purgative principle is probably an. acrid resin. The oil- cake from Indian and Tahitian seeds has respectively the following percentage composition :— Indian. Tahitian. Oil es 8-93 9-20 Organic matter 7404 74°24 8:96 9°36 7:07 7°20 were respectively equal to 52 and 51-7 per Aleurites cordata) has been examined by harm. Journ, [3] xv., 636). It is the aarkable drying properties. 7° is ted b, EUHPORBIACEZ:. : 281 sh to convert one thousand grams of oil into potash soap. fatty acids amounted to 94°] per cent., melting at 39°, ntaining some white crystalline plates melting at 67°. CROTON TIGLIUM, Linn. Fig. —Bentl. and Trim., t. 239; Rheede, Hort. Mal. ii., 3. Purging Croton (Hng.), Croton cathartique (fr.). -Hab.—China. Cultivated in India. The seeds and oil. PP ernacular. —Jaypél, Jamélgota (Hind.), Jaypal (Beng.), palo (Guz.), Jamélgota (Mar.), Nepéla (Can., Tel.), Nervalam (Tam.), Nirvélam (Mal.), Kanako (Burm.). History, Uses, &c.—Croton seeds were not known to the ancient Hindu physicians ; in recent Sanskrit works they — are noticed under the names of Jayapila, Tittiriphala and akaphala, and are described as heavy, mucilaginous and gative, useful in fever, constipation, enlargements of the ominal viscera, ascites, anasarca, cough, &c., expelling bile phlegm. They are directed to be boiled in milk, the outer and embryo having been removed, to fit them for internal inistration. The following prescription from the Bhava- casa may be taken as an example :— - Mahanaracha rasa.—Take Chebulie myrobalans, pulp of Jassia fistula, Emblic myrobalans, root of Baliospermum axillare amt Pier orhiza Kurrooa (tikta), milky juice of Euphorbia m to a coarse powder, and boil in four seers of water the latter is reduced to one-eighth. Then take a told of ked Croton seeds, tie them in a piece of thin cloth, and boil them in the abovementioned decoction, till the latter is reduced to the consistence of a fluid extract. To this extract add a powder composed of eight parts of purified Croton seeds, three parts of ginger, and two of black pepper, mercury, and sulphur — quantity sufficient to make a pill mass; rub them together twelve hours, and make into two-grain pills. These are IIl.—36 Sree 282 EUPHORBIACEZ. given with cold water in tympanitis, colic, ascites, &e., as a drastic purgative. After the operation of this medicine, rice should be given with curdled milk and sugar. The Indian names for Croton seeds lead us to suppose that they were first introduced into the country through Nepal. Under the name of Dand they were known to the Persians at a very early date, and were doubtless introduced into that country from China by the Caravan route through Central Asia. The Arabs retained the Persian name, but also called them Hab-el-khatai, “ Cathay seeds,” and Hab-el-saldtin, “Sultans” seeds.” Ibn Sina describes them under the name of Dand-el- : sini, ‘China Dand,” and also mentions an Indian Dand of smaller size (probably Baliospermum seeds). Ainslie states that Croton seeds were known to the Arabs under the name of Fill, but this is incorrect, as may be seen by referring to Tha Sina, who describes Fil as an Indian drug having the properties - of the Mandrake. Mahometan physicians describe the eed as detergent, a purgative of phlegm, black bile, and adus humors; and recommend their use in dropsy, calculus, gout, : and other diseases arising from cold humors, On account of its irritant action upon the fauces, the seed, after having been boiled in milk, is to be crushed and enclosed in a raisin for administration, The author of the Makhzan remarks that the Hindus give small doses with fresh ginger tea, to children, as a remedy for whooping cough: He also notices its irnitan action upon the skin, and its use as an external application to tumours, &e,; should excessive purging occur, he directs _limejuice to be administered. The envelopes of the seed and : plumule must always be rejected. Croton Tigliwm was first described by Christoval Acosta in 1578, afterwards by Rh in 1679, and Rumphius in 1743. In 1812, Drs, White and Marshall brought the use of the seeds as a purgative to the notice of Europeans in India. The former gentleman gives _ the following directions for their administration, which he ‘Feceived from a learned Parsee Vaidia of Surat :—“ After = having removed the shells from the seeds, tie the kernels n sg small piece of like a bag; then put this into as mut EUPHORBIACER. 283 ung water as will cover the bag, and let it boil; secondly, boiled, split the kernels in two and take a small leaf hem, which is said to be poisonous; and thirdly, pound hole into a mass, to which add two parts of Katha ), and divide into pills of two grains each, two of e sufficient for one dose.’ The addition of the Katha correct the acrimony of the drug, and to ‘prevent any of the bowels. , e (Mat. Indica, Vol. I., p. 105) notices the use of the oil (nervalum unnay) by the Tamils as an external ution in rheumatic affections, but it does not appear to ‘been used for internal administration until the year 1821. r. London Medical Depository for January 1822.) In modern European medicine, croton oil, more or less diluted, ed externally as a counter-irritant, and causes an abundant ar eruption. This effect is increased by the addition of alkali to the liniment. Internally it is given in doses tol minim asa purgative, and is particularly valuable cases in which the condition of the patient prevents om swallowing; it may be placed on the back of the The oil has also been used with success as an anthel- In modern pharmacy its chief consumption is in ation of castor oil capsules. Yescription.—Croton seeds (graines de Tilly) are oblong, t half an inch long, and not quite 3 of an inch broad. dorsal and ventral surfaces are arched, the former more ninently than the latter. The testa is black, but covered for 10st part by a thin cinnamon-coloured membrane; it is thin brittle, and contains an abundant oily Dien enclosed. delicate white membrane (endopleura). Between the two sof the albumen are two foliaceous cotyledons, and a thick radicle. The structure of these parts closely resembles that of the albumen and embryo of Ricinus communis, _ Chemical composition—The fats present in croton oil are ycerides of stearic, palmitic, myristic, and lauric acids, and of al volatile acids of the same series, like acetic, butyric, and 284 - _ EUPHORBIACEZ. valerianic acid; also the volatile ¢iglinic acid, C5H®O?, which was recognized by Geuther and Frélich (1870), but had previously been observed by Schlippe (1858), who considered it to be identical with angelicic acid. However, it melts at 64° C., boils at 198°5°C., and is identical with Frankland and Duppa’s methylerotonic acid. In the fraction boiling above the temperature named, capronic, cenanthylic, or similar acids are probably present. They did not succeed in obtaining from croton oil an acid having the composition of Schlippe’s erotonie acid, C*H°O’, E. Schmitt(1879) corroborated these statements, and found among the volatile acids also formic acid, Schlippe’s erotonol, C'8H*80*, has likewise not been obtained by other chemists; it was stated to be a yellowish viscid mass of a faint odour, and to be the rubefacient principle of croton oil. The drastic rubefacient properties, according to Buchheim (1873), reside in crotonoleic acid, which is present in the free state and as glyceride, and which seems to be related to ricinoleic acid, since, like the latter, it yields with nitric acid cenanthic acid, and on the distillation of its sodium salt gives cenanthol. (Stitlé and Maisch.) : _H. Senier (Pharm. Journ. [3], XIV., 446, 447) has shown that when alcohol (sp. gr. *794—-800) is mixed in equal volumes with English pressed croton oil, perfect solution takes place, the mixture being permanent at all ordinary tempet@ tures, and this is equally true when any less quantity of alcohol is used; when, however, the proportion of alcohol to croton oil becomes as seven volumes to six, or any large? proportion of alcohol, then a part of the croton oil separate’ This part varies in quantity in the case of different samples of oil. That part of the croton oil which separates when the alcohol is in excess is afterwards insoluble in any proportion of alcohol. But that portion of the oil dissolved by alcohol is; whee Separated, soluble in all proportions. The author has shown that the part of croton oil soluble in alcohol contains the ORE Principle, while the portion insoluble in alcohol 18 viene non-vesicating. He also shows that the purgative Properties of croton oil reside entirely in this insoluble, EUPHORBIACEZ. 285 © -vesicating part. The author has endeavoured to ascertain to hat constituent of the soluble portion of the oil the vesicating properties are due, and has traced these properties to the non- volatile fatty acids, chiefly to those which have the lowest melting points, are least readily saponified by alkalies, and are first liberated when the alkali soap is decomposed by acids. attributes the purgative action not to the free acids, but the combination in which they exist in the oil, These conclusions not appearing satisfactory to Brcko heydt, a pupil in the University of Dorpat. Upon the basis of the results obtained, Professor Kobert now (Chem. Zeit., April 6, 1887, p. 416) attributes the activity of croton oil, both asa vesicant and as a purgative, to crotonoleic acid, not to be free state, in which it is freely soluble in alcohol, and in combination as a glyceride. The glyceride does not possess poisonous properties, but the free acid acts as a powerful irritant to the skin and the intestines (purgative). According to Professor Kobert, the crotonolglyceride is attacked and split up like other glycerides by the ferments of the juices of — the stomach, and the crotonoleic acid being set free then exercises its purgative influence. 40* are obtained, which are sparingly soluble in cold alcohol and ether, and are not precipitated bv lead or silver salts. (National Dispensatory.) Messrs. A. G. Perkin and W. H. Perkin, Junr.(Berichte, 1886), have recently separated from Kamala a substance which they name Mallotorin, C'.H}°O? or C!®H'605, It was obtained by shaking powdered Kamala with bisulphide of carbon, evaporating the solution, and treating the residue with just enough bisulphide of carbon to remove the resinous impurities. It was finally purified by crystallization from benzine oF toluene. It formed small flesh-coloured needles, soluble in alkalies, aleohol and acetic acid, but insoluble in water. It appears to be identical with the rottlerin of Anderson. Later still, L. Jarvein (Ber., xx., 182) obtained a yellow crystalline substance from Kaméla, melting at 200°, to which he gave the same name and formula as Anderson’s rottlerin. The bark of this tree is astringent, and Professor Hummel found it to contain 6°5 per cent. of tannin. Carefully selected, Kaméla, according to P. Siedler, will not contain more than 1°5 per cent. of ash, whilst the commercial article yields from 21°8 to 49-1 per cent. By sifting, fractions may be obtained containing as low as 5-2 and as high as 25 pet cent. High percentage of mineral matter may be due to careless collection, or to adulteration ; in the latter case, the ash may range from 50 to 80 per cent. The percentage of ash has notably increased of late, and by sifting it is often impossible to get the drug containing less than 14 per cent. of ash. Of 45 samples examined by the author, only three contained less than 6 pet cent. (Pharm. Zeitg., 1891, 162.) Commerce.—Kaméla is collected in the N.-W. Provinces, the Concan and Madras, and is distinguished by the collectors a5 © two qualities, Kapila and Kapili; the latter is the best, and is obtained by shaking the fruit only in a basket to separate the glands. Kapila consists of the glands and other parts of the plant, and has a greenish tinge. The collection of the drug is industry of the hill Khonds in Ganjam, who sell a few measures for a few measures of rice or a yard of cloth. _ The average value of the best red Kaméla is Rs. 11 per maund of 41 lbs. The high winds laden with dust, which often prevail in India, cause a certain amount of impurity in the drug from the adherence of dust to the capsules and leaves of the Native dealers test the drug by taking it up on the moistened finger and rubbing it firmly upon a piece of white per; if of good quality, a smooth paste is formed and the paper is stained of a bright-yellow colour. RICINUS COMMUNIS, Linn. Fig.—Bentl. and Trim., t. 237; Sibth. Fl. Gree. x., t. 952 ; Hayne, Arneigew. x., t. 48; Rheede, Hort, Mal. ii., t. 32. Castor plant (Hxg.), Ricin commun (F’r.). _ Hab.—Africa P Cultivated throughout India. The leaves, seeds, root, and oil. _-~Vernacular.—Arandi (Hind.), Erandi (Mar.), Bherenda a (Beng.), Amanakkam-chedi (Tam.), Amudapu-chettu (Te.), _ Avanakku (Mal.), Karala-gida (Can.), Erando (Guwz.). 2 History, Uses, &c.—The Castor plant is called in : Sanskrit Eranda, Ruvu, Ruvuka and Uruvuka, and the red _ variety Raktairanda; the root and the oil obtained from the __ seeds have been used medicinally by the Hindus from a very remote period, and are mentioned by Susruta. Both root and oil are described as purgative and useful in costiveness, flatulence, rheumatism, fever and inflammatory affections; on account of its efficacy in rheumatism the plan bears the synonym of Vatéri (vdta-dri). As a purgative the oil is directed to be taken with cow’s urine or an infusion of ginger or the decoction of the ten roots known as dasamula (see ‘Vol. I., p. 248). The seeds freed from the husks and germs, and boiled in milk and water, form a decoction which is given in _ rheumatism; a decoction of the root with carbonate of potash Fea et ee) ey et eye ae : 309 EUP. ACER is also prescribed, and most compound medicines given in rheumatic and neuralgic affections contain the root. The leaves are applied to the breast to stop the secretion of milk, and, boiled with the root in goat’s milk and water, they are used as a local application in ophthalmia. When applied to the abdomen they are popularly thought to promote the menstrual flow; in Govardhana (203), the halikavadhu, or “ peasant woman,” is represented as lying in pain upon the leaves of the Eranda. In the proverbial language of the Indians the Castor plant is emblematic of frailty ; they say :—Naukri arand ki jar hai (ser- vice is like the root of the Castor plant). The Arabs appear to have first become acquainted with the tree in India, as they call the seeds Simsim-el-hindi, “Indian Sesamum,’’ and the plant Khirvaa (¢ 5»), a word which signifies any weak or frail plant; the properties they attribute to it are also those mentioned by Sanskrit writers. Again, in the Saptasataka of Hila, we find the large and swelling breasts of the peasant girl likened to the Eranda leaf, and in Arabic we have the expression é©) 4 31, 1688-80 W000 i _ Most of the castor seed goes to Italy, * - BUPHORBIACES. 811 The exports | ot oil, mostly from Bengal, during the same ee ” ” ” ” ” ” 888-89...2°7 ce) : ” ” 26 93 3%) BALIOSPERMUM AXILLARE, Blume. 3 Fig.— Wight Ic., t. 1885; Rheede, Hort. Mal. z., t. 76. ~Hab.—Tropical and Subtropical Himalaya. Deccan Peninsula. The root and seeds. Vernacular.—Danti (Hind., Beng.,Mar.,Gus. sogsinshiaee = (Tel.), N4ga-danti (Tam., Ma/.). _ History, Uses, &c.—This plant, in Sanskrit Danti, Nag4danti or Danta-mulika, with numerous synonyms, such as Upachitra, Makulaka, &c., is much used in Hindu medicine where purgation is indicated, the root being generally prescribed. _ The seeds (Danti-vija) are also used, and are sometimes sold in the shops as croton seeds. The following formula from Chakradatta _ will show how the root is prescribed :— ~~ § Danti haritaki.—Take 25 large chebulic myrobalans and enclose them ina piece of cloth, then take of the roots of Baliospermum axillare and Ipomea Turpethum, each 200 tolas, water 64 seers, boil them together till the water is reduced to 8 seers. Strain the decoction, take out the chebulic myrobalans and fry them in 32 tolas of sesamum oil. To the strained decoction add 200 tolas of old treacle, then boil till reduced to the proper consistence for a confection. Now add to the mass the following substances : powdered root of Ipomea Turpethum 32 tolas, long pepper and ginger, each 8 tolds, and stir them _ 312 EUPHORBIACEZ. well; when cool, add 32 tolas of honey ; cinnamon, cardamoms, d tejpat leaves, and the flowers of Mesua ferrea, each 8 tolas, and prepare a confection. The chebulic myrobalans should be kept embedded in the medicine. ‘Two tolas of the confection and one of the myrobalans are to be taken every morning.” A more. simple formula from the Bhavaprakasa is the Gudéshtaka. Take of danti, trivrit (Ipomea Turpethum), and plumbago root, black pepper, ginger and long pepper root, equal parts in fine powder; treacle, equal in weight to all the other ingredients, and mix. Dose about a tola every morning, — in flatulence, anasarca, jaundice, &c. Rheede says of Danti:—Folia, radix atque fructus, tanta purgandi pollent energia, ut solus odor catharsin excitet: folia extrinsice applicata articulari medentur morbo.” Roxburgh remarks :—“ The seeds are esteemed by the natives a good purgative ; they administer one seed bruised up with water for every evacuation they wish the patient to have. There © would appear to be little doubt that the seeds of this plant were the original Dand of the Arabian physicians, but were sub- sequently superseded by those of Croton Tiglium, as has been the case in India. Description.— Roots nearly straight, seldom branched, about as thick as the finger; bark brown, scabrous; wood yellow- ish-white, soft and tough. The outer layer of the bark consists of several rows of brick-shaped brown cells, mostly empty, but some of them containing a dark reddish-brown resin ; within this the parenchyma is so loaded with conglomerate raphides that its structure is with difficulty seen ; it has many cells filled with resin as in the suber, and very numerous yellow liber cells. The wood is loaded with starch. The seeds weigh about one and a half grains each, and are exactly similar to very small castor seeds. Commerce.—The seeds are no longer found in the bazars, having been superseded by the imported croton seeds; the root is also difficult to obtain, that sold in the shops us Danti-mul being usually the root of Ricinus communis. A : HISTORY 4 THE PRINCIPAL DR OF VEGETABLE ORIGIN BRLIISH INDEA, BY , WILLIAM DYMOCK, BRIGADE-SURGEON, RETIRED, "LATE PRINCIPAL MEDICAL STOREKEEPER TO GOVERNMENT, PC. J. H. WARDEN, DAVID HOO! E SURGEON-MaJOR, BENGAL ARMY, QUINOLOGIST TO THE Gol PROFESSOR OF CHEMISTRY IN AND MENT OF MADRAB, e THE CALCUTTA MEDICAL = ; COLLEGE, | OOTACAMUND. We; Bot. Garden, PAK? Vi. Zonvon: KEGAN, PAUL, TRENCH, TRUBNER & Co, Lp. Bombay :—EDUCATION SOCIETY'S PRESS, BYCULLA. Galeutta:—THACKER, SPINK & Co. PHARMACOGRAPHIA INDICA. A HISTORY THE PRINCIPAL DRUGS OF VEGETABLE ORIGIN BRITISH INDIA, a WILLIAM-.DYMOCK, BRIGADE-SURGEON, RETIRED, LATE PRINCIPAL MEDICAL STOREKEEPER TO GOVERNMENT, ). J. H. WARDEN, © DAVID HOOPER, : re GEON-MAJOR, BENGAL ARMY, QUINOLOGIST TO THE GOVERN- MENT oF MADRAS, OOTACAMUND. COLLEGE, PART Vi. “Zouvon:—KEGAN, PAUL, TRENCH, TRUBNER & Co., Lp. pmbay EDUCATION SOCIETY’S PRESS, BYCULLA. — tta: THACKER, SPINK & Co. 1893. Fak “PRINTED AT THE EDUCATION 5 ae » tah ray hr cong ey Sr Dr. William Dymork. issuing the sixth part of the “ Pharmacographia Indica,” with much regret we have to announce the death of the d was educated first at. Bristol, then at Rugby, and after- wards at Oxford where he took a B.A. degree. After a course _of medical studies, he became M.R.C.'S. Eng., he then joined the Indian Medical Service, and was appointed to the Bombay residency in 1857. He saw active service during the Mutiny “with the Kathiawar Field Force against the Wagheers, and was present at the capture of Dantal Hill. For two years he was England he was appointed in 187 1 to be Principal of ne Medical Store Department, ee and in this capacity he He largely increased the local manufacture of galenical pre- garations, and introduced modern and improved machinery in the Depét laboratory. For his skilful and efficient manage- ment he was thanked by Government on three separate occasions. Dr. Dymock was proficient in Arabic, Persian, mskrit, Hindustani, Mahratti and Guzrati; he was familiar sh Greek and Latin, and corresponded freely in F ench German and Portuguese. He was a Fellow and I ne author. This sad event, caused by influenza combined ae h cystitis, took place on the 30th April 1892, at his re- lence on Malabar Hill, Bombay, in the fifty-eighth year of his age. William Dymock belonged to the west of England, — ttac the Indian Navy, and visited the ports of the Persian Gulf and the East African Coast. In 1868 he served { 2 the University of Bombay, and being an eminent linguist he was for many years a member of the Presidency Board for the examination of officers in Oriental languages. Bombay being the drug market of the East, he TR himself of the many Gincslanitios of examining new and rare vegetable products, and having a good knowledge of botany, he was often able to identity dhs sources of the drugs. He was for some years Professor of Materia Medica i in fie Grant Medical College, and, as a teacher of this science, he was said not to have a rival aa India. Dr. Dymock’s literary contributions to the Pharmaceut Journal commenced in 1875 with a paper on “ The Asafeti das of the Bombay Market,” this was followed by others on *“ Ammoniacum and Dorema Root,” “ Myrrh” and “Chaul-— moogra Oil.” In 1876, the well-known “ Notes on Indian Drugs ” first appeared, and were a feature of the Journal for the next four years. Specimens of these drugs were at the 1888, and next year the first part of the ane ee Indica” was issued. The greater responsibility of this wor rested with him, and to it he gave his whole time until Ee total illness compelled him to cease from his labours a few days — re he died. The manuscript of the sixth part, as far as he uld prepare it, was written, and he compiled an index and an dix which will be printed as soon as possible. 4/t. Dymock was one of the founders of the Anthropologica ys of ‘Bombay, and most actively supported the Society 2 << Sevibens of member of the Council, President ad Literary SeerMery... The ocho his . India P Anthropogonic Trees,” ‘On the Narcotics and Spices of the ast,” “The Flowers of the Hindu Poets,” On the use of es ‘urmeric in Hindu Ceremonial and “On the use of Ganja 1d Bhang in the East.” He also read papers before the. S abay Natural History Society and the Medical and Physical He was honorary member of the Pharmaceutical and learned societies. In 1887 he was awarded the Hanbury Medal, for his researches in the natural history and y of drugs. a scientific investigator Dr. Dymock was thorough and ientious; in his literary researches he was careful and staking ; his disposition was kind and obliging. Although man of varied and great talents he was of very retiring habits, and had very few social acquaintances. His sub- ordinates regarded him as a father, and his correspondents in different parts of the world could always count upon a “punctual and friendly reply to their enquiries. He was the reatest pharmacognoscist in this country, and many besides ourselves will mourn that such a useful career was so suddenly rminated, ide C. J. H. WARDEN. bia delphinifolia .., edicularis pectinata we BIGNONIACER, hee ee ACANTHACER. phila spinosa eve = a wo Ecbolium Linneanum Poe Adhatoda Vasica ... . .., Rhinacanthus communis ... ee Lippia nodifiora ie Verbena officinalis ., iw a allicarpa lanata .. Wad Tectona grandis Premna integrifolia re ». herbacea ... ‘ tomen oe Gmelina arborea Vitex Ne a a » trifolia ee Bee Agnus-castus wae Olerodendron inerme we infortunatum es ne oe 35 oo Avicennia officinalis Ocimum basilicum... —.. vi gratissimum si... 9? be rae Salvia plebeia sae we “9D a5 ar Coleus aromaticus st lus carn . Lavandula Steechas ma 2: eee oe . ‘0 mon parviflorus Mentha sylvestris ... arvensis ve Aieromeria capitellata ‘ rigan mary} jorana eee aceite w ipvviaaatin Zataria multifiora ... iziphora tenuior .., Melissa officinalis .., arrubium vulgare Anisomeles malabarica ucas aspera, &c. Leonotis nepetefolia _ PLANTAGINES. ‘Plantago ovata .. a. ms ed se chy - Nycraginen. Boerhaavia ms .., ise Mablisdeaa AMARANTACER, Achyranthes aspera ae Amarantus spinosus ffrua javanica, eee coe ca ata Celosia argentea .., ae aN CHENOPODIACER. 130 ee 132 = Vise CONTENTS. PAGE THYMELMACE. . 126 Aquilaria Agallocha we Ly) 126 Malaccensis ... Lasiosiphon eriocephalus ,., LORANTHACES. album. Toantna sp. sae ee SANTALACER. s636 . 138° Santalum album ... ate ye 20d weutee EUPHORBIACE2. gag 408 tht Euphorbia pilulifera ss... ne thymifolia ... » ‘Tirucalli ... wiscd4] “ neriifolia a » 143 is antiquorum ... . 146 resinifera 2 Payllantivas 2 Emblica... j ticulatus ... te: eset vs 2 arina equisetifolia .., CUPULIFERZ. Betula utilis = ta ‘ Salix Caprea eos ooe GNETACER. Ex vulgaris .. iis ia pachy: clada. ConIFERm. Juniperus communis __... ‘Taxus baccata we por CycaDAcER OxcHIDER. campestris tos macraei : ghii te . wae Canna indica TRipEz. Tris oe TOCUS Sa’ Pasdanthus 0 es AMARYLLIDER, Curculigo So epigr Crinum asiati BRoMELIACE2R. 'Ananas sativa wes CoMMELINACER. Commelina bengalensis Tradescantia axillaris XYRIDER. Xyris indica ie cifer: Borassus flabellif liformia poetics ee < alhte Beas PANDANACER. Pandanus odoratissimus ... TYPHACER Typha angustifolia ee AROIDER, Acorus Calamus en officinalis Alo ocasi ia indica eam antiquo morp. hophall ‘campansiatas ‘ ynanther Se Lr ( metptood e spiralis ] icaria CONTENTS, PAGE ve. 507 . 538 GRAMINER. Andropogon Schcenanthus re niger lanig: re i citratus tee - Nardus * an odoratus.., a ite Coix1 : Era agrostis eynosnrades és Cynodon dactylon .. ies a entaceum ... Paspalum scrobiculatum ,.. Hygrorhiza aristata ca Eleusine coracana .., fou Sorghum saccharatum... BBTA -ve0 fhe Saccharum Fiticss. Polypodium vul vo quenieulaeel Adiantum venustum AP es prc dss falcatum tee LicHENEs. Parmelia mrscenmer perla ° oon oo Fonat. Mylitta lapidesoens prs Boletus val ae Pol seer ; odie inalis oa AIG. 2? cornenm ... tes Gracilaria lichenoides_ _... Laminaria saccharina... RUPHORBIACES. — 813 TRAGIA INVOLUCRATA, Linn. Fig.—Burm. Zeyl., t. 92; Rheede, Hort. Mal. ii. t. 39; cannabina, A. Juss. Tent. Euphorb., t. 15, 49 B. Hab.—Thronghout India. The root. Vernacular.—Barhanta (Hind.), Bichati (Beng.), Kanchuri, — Karchkuri, Khajkolti (Mar.),- Dulaghondi Feb), ? . Betory. ses. .. tie very variable plant, of which varieties are described in the Flora of British India, is the hik4li of the Raja Nirghanta, where it is said to bear the name in Marathi and to be called Haligilu in Canarese. It $ recommended in bilious fever, and as a diuretic and alterative. theede says of it:—‘‘ Conducit in febre ossium, ac servit pro pruritu corporis; in decocto data urinam suppressam movet.” Ze also notices its use on the doctrine of signatures as a emedy for the sting of the Ray fish. Ea inalic (ii., 61 and 389) says :—‘‘ The root, which is sometimes alled Coorundootievayr,’ has in its dried state but little taste or , though in its more succulent condition it has a rather sit odour ; it is considered as diaphoretic and alterative, is prescribed in decoction, together with other articles of e virtues, to correct the habit in cases of mayghim (cachexia), in old venereal complaints, attended with anomalous symptoms ; an infusion of it is also given as a drink in ardent r, in the quantity of half a teacupful twice daily.” n the Concan the roots of these plants are used to aid the ti of Guinea-worm, a paste made from them being lied to the part. A paste of the roots with Tulsi juice is o used as a cure for itchy eruption of the skin. In Tanjore, root is boiled with cow’s milk and taken at bedtime for dry ough. Description.—Shrubby, climbing, 4 to 5 feet high; leaves petioled, 3-divided, serrate, hairy, 2 to 4 inches long ; ipules half lanceolate; racemes erect, many-flowered ; male wers humerous on the upper part of the Bee's very su IIl.—40 314 EUPHORBIACE. yellow, each with three bracts; female flowers beneath the male, two on each raceme, with the calyx leaflets pinnatifid. The plant stings like the nettle. For a description of its varieties, the reader is referred to the Flora of British India. EXCACARIA AGALLOCHA, Linn. Fig.— Wight Ic., t. 1865 B; Rheede, Hort. Mal. v., t. 45, Blinding tree, Tiger’s milk tree (Eng.), Arbre aveuglant (F’.). Hab.—Tidal forests of India. The juice and cork. Vernacular.—Gaoura, Uguru, Gangwa, Geria (Beng:), Chilla (Zel.), Haro (Can.), Gevi, Phungali, Hura (Mar.), Tillai-cheddi (Zam.). History, Uses, &c.—This tree was named Agallocha by the old botanists, from a supposition that a kind of Aloe-wood was yielded by it; but Loureiro, speaking of EH. cochin-chinensis, remarks, “nec agallochum, quamvis spurium, in illa inveneri.” The wood is white, soft, and spongy, and has no aromatic pro- — perties. All parts of the tree abound in an acrid milky juice, which causes intense pain if it gets into the eyes; this juice 1s said to be used in Australia and New Guinea to cure ulcers, leprosy, &c. If collected it hardens into a kind of caoutchouc, a grain or two of which is used by the boatmen on the Western Coast of India as a purgative. Ainslie (ii., 438) states that @ decoction of the leaves is occasionally given by Hindu doctors in epilepsy, in the quantity of a quarter of a teacupful twice daily. This decoction is also used as an application to ulcers. Smith (Zeon. Dict., 5) states that in Fiji the plant is employed for the cure of leprosy, its mode of application being very singular. The body of the patient is first rubbed with the greet leaves ; he is then placed in a small room and bound hand and foot, and 8 small fire is made of pieces of the wood, from which rises @ thick smoke ; the patient is suspended over this fire, and _ ‘Femains for some hours in the midst of the poisonous smoke, enduring the most agonising torture and often fainting. When thoroughly smoked, is removed, and the slime is scraped EUPHORBIACEA. 315 from the body; he is then scarified and left to await the result, which, if the patient survives, is said to be a cure. From the lower part of the trunk and roots of this tree a soft, light, reddish suber is obtained, which is sold by the itinerant medicine men of Western India, under the name of Tejbul, as an aphrodisiacal tonic. It occurs in irregular-shaped pieces about half an inch thick, and often as large as the palm of the hand, from which the epidermis has been removed by scraping d trimming. The structure is that of coarse cork, the cells being about six times the size of ordinary cork cells. This sub- stance has a glistening appearance, and is always kept saturated h water, so that on breaking it, it appears to be full of juice. On some parts of the Coast it is said to be used for making floats for fishing nets. Description.—A small evergreen tree or shrub, growing along with Rhizophora and Avicennia, and sometimes called the “milky mangrove.” Leaves ovate, between fleshy and coria- _ eeous, 2 to 4 inches, entire or sinuate crenate, pale brown when dry, base acute or rounded; nerves many, very faint, sub- horizontal; petiole $ to 1 inch. Flowers fragrant, male spikes numerous, 1 to 2 inches; female racemes few, 4 to 1 inch, Bracts of male spike with one flower and several minute bractioles. Filaments much lengthened after flowering. Styles free nearly to the base. Seeds subglobose, smooth. The ‘variations in the size of the fruit and seeds are remarkable. (FI. Br. Ind.) Plants of minor importance belonging to this order, which are used medicinally, are:— - Macaranga Roxburghii, Wight Ic., t. 817, a small _ tree of the Deccan Peninsula, with peltate, cordate leaves, small green flowers, and fruit the size of a pea, The young shoots and fruit are covered with a clammy, reddish secretion having an odour like turpentine. The country people use the following _in Jarandi (Angl., Liver):—One part of the young shoots, 7 8 parts of the young shoots of Khoréti (Ficus asperrima), are 316 URTICACEZ. sprinkled with hot water and the juice extracted; in this is rubbed down 2 parts each of the barks of both trees. The preparation may be administered twice a day in doses of } of a seer. The Marathi name is Chéndvar. The bark contains 18°4 per cent. of tannic acid, giving a blue-black precipitate with ferric chloride, and the air-dried bark leaves 11. per cent. of mineral matter on incineration. Chrozophora plicata, A. Juss., Burm. Ind., t. 62, f. 1, isa common weed on cultivated ground, and in the bottoms of dried up tanksin many parts of tropical India in the cold season. It is reputed to have alterative properties, and is mentioned by Ainslie as a plant which Dr. fF. Hamilton had brought to him in Behar, as one of those which was supposed to have virtues in leprous affections; the dry plant is made into a decoction to which is added a little mustard. (Mat. Ind., ii., 398.) Sebastiania Chamezlea, Muill-Arg., the Cadi-avanace of Rheede (ii., 34), and the Bhui-erandi otf the Concan, is a small plant, with linear, finely serrated leaves and small spinous cocci, the juice of which in wine is used as an astringent; a ghrita of the plant is considered to be tonic, and is applied to the head in vertigo. URTICACEA. GIRONNIERA RETICULATA, Thuaites. - Fig.—Bedd, Fil. Sylv., t. 313. Syn., Celtis reticulata. _Hab.—Sikkim, Himalaya, Assam, Burma, Pegu, Deccan Peninsula, Ceylon. The wood. Vernacular.—Koditéni (Tam.), Kho-manig (Nilgiri), Narakiya- ood (Ind. Bazars). History, Uses, &c.—This wood does not appear to be mentioned by Indian medical writers, nor can we find any i: record of ite. collection in India for medicinal use, the bazars _____ being supplied from Ceylon, where it has probably been in use _ Thunberg says :— “The tree is called by the Dutch Strunt- hout, and by the Cingalese Urenne, on account of its disgusting odour, which resides especially in the thick stem and the larger branches. The smell of it so perfectly resembles that of human -ordure, that one cannot perceive the smallest difference between them. When the tree is rasped, and the raspings are sprinkled with water, the stench. is quite intolerable. It is neverthe- less taken internally by the Cingalese as an efficacious remedy, hen scraped fine and mixed with lemon juice, it is taken ‘internally, as a purifier of the blood in itch and other cutaneous eruptions, the body being at the same time anointed with it externally.” (Zhunberg’s Travels, iv., 234.) - Thunberg obtained leaves and young plants of the tree, but no blossoms; the plants were all killed by cold in the English Channel. The Portuguese call the wood Pao de merda or Pao sujo. In ‘India it is burnt as a fumigatory to mre away evil spirits; the bazar name signifies ‘‘ hellish incense.”” In Ceylon, according to Mr. J. Alexander, it is hung up near dwelling-houses as a charm to keep away evil spirits. As sold in the bazars it is a _ light-brown wood in irregular-shaped pieces, having a pene- trating odour, exactly similar to that of fresh human ordure. Chemical composition.—The wood has been examined by Prof. W. R. Dunstan. By distillation with water a minute quantity of a solid crystalline substance was obtained. It possessed a - fecal odour, and after purification melted at 93°5°C. Its physical and. chemical properties were not those of a-naph- thylamine. It afforded a crystalline picrate, by the analysis of which the substance was shown to possess the composition of - methyl-indole (C29H9N), and by its physical and chemical _ properties it was proved to be identical with the Pr. 3 methyl- indole, or skatole, which Brieger isolated in 1877 from human feces, and Salkowski soon afterwards obtained from among the putrefaction products of animal proteid. Nenchi has observed the formation of the same substance when potash is fused with URTIOACEZE. 317 albumen, and it has also been prepared synthetically. Skatole 7 318 URTICACEA. from G. reticulata corresponds in all its properties with syuthetical skatole from propylidene phenyl-hydrazide. The occurrence of skatole in a plant has not hitherto been observed; it has appeared to be a characteristic product of the bacterial resolution of animal proteid. (Pharm. Journ., June 15th, 1889.) The nomenclature followed is that which has been proposed by Emil Fischer. The benzene nucleus of indole being desig- nated by Bz, and the pyrrole nucleus by the contraction Pr, the nitrogen of the pyrrole nucleus is numbered 1, as well as the corresponding carbon atom of the benzene nucleus; thus the formula of skatole is— CH Holoptelea integrifolia, Planch., Wight Ic., t. 1968; Roxb. Cor. Pl., t. 78; Bedd. Fl. Sylv., t. 810, a tree extending from the Lower Himalayas to Travancore, has a mucilaginous bark, which is boiled and the juice squeezed out and applied to rheumatic swellings; the exhausted bark is then powdered and applied over the parts covered by the sticky juice. The vernacular names of the tree are Papri (Hind.), Aya (Zam.), Nayili (Tel.), Vavala (Mar.), Rasbija (Can.) CANNABIS SATIVA, Linn. Fig.—Bentl. and Trim., t, 231; Reichb. Ic. Fl. Germ., t. 655; Rheede, Hort, Mal. z., tt. 60, 61. Hemp (Eng.), Chanvre (Fr.). Hab.—N.-W. Himalaya, Cultivated in India. The leaves, female flowering tops, resinous exudation, and seeds. URTICACER. 319 Vernacular.—The leaves—Bhang, Sabji (Hind., Beng., Mar.), anja-ilai, Bangi-ilai (Zam.), Ganja-aku, Bangi-aku (Te/.), anchéva-ela (Mal.), Bangi (Can.), Bhang (Guz.). Flowering —Ginja (Hind., Beng., Guz.), Ganja (Tam., Tel., Mar.), cha (Mai.), Bangi (Can.). The resin—Charas (Hind., ong., Guz., Mar.), Ganja-pél (Tam.), Ganja-rasam (Tel.), nchava-péla (MMal.), Bangi-gondu (Oan.). The seeds— nje-ke-bij (Hind.), Ganja-virai (Tam.), Ganja-vittulu( Ze/.), nchava-vitta (Mai.), Bangi-bija (Can.), = — ) anga-cha-bi (Jar.), Bhéng-nu-bi(Guz.). : History, Uses, &c.—The hemp plant, in Sanskrit ga and Indrasana, ** Indra’s hemp,” has been known in the East asa fibre plant from prehistoric times. It is mentioned along with the Vedic plant Janjida, which has magic and medicinal properties, and which is described in the Athavaveda _ (ix., 34, 35) as a protector, and is supplicated to protect all animals and properties. The gods are said to have three times created this herb (oshadhi). Indra has given it a thousand eyes, d kiillng all monsters ; it is praised as the best of remedies, is worn as a precious talisman; along with hemp it prevents wandering (vishkandha), fever and the evil eye. De Gubernatis says that in Sicily the peasant women still believe in hemp as an infallible means of attaching their sweethearts. On Good Friday they take a thread of hemp and twenty-five needlefuls of coloured silk, and at midnight weave them together, pate the following lines:— Chistu é c4nnavu di Christu Servi pi attaccari a chistu. “This is the hemp of Christ; it serves to attach this man.’ “They then enter the Church with the thread in their hands, and ‘at the moment of the consecration of the host, they make three knots in it, adding at the same time some hairs of the man they are in love with, and invoke all the demons to attract him to his sweetheart. (Cf. Mattia ’di Martino, Usi e eredenze popolari _ Siciliane, Woto, 1874.) Burns in “ Halloween” notices & a 320 URTICACE 2. closely-allied superstition. The intoxicating properties which the plant possesses in its Eastern home appear not to have been discovered until a more recent date, but in the fifth chapter of Menu, Brahmins are prohibited from using it, and in the sacred books of the Parsis the use of Bana for the purpose of procur- ing abortion is forbidden. In Hindu mythology the hemp plant is said to have sprung from the amrita produced whilst the gods were churning the ocean with Mount Mandara. It is called in Sanskrit Vijaya, “ giving success,” and the favourite | drink of Indra is said to be prepared from it. On festive occasions, in most parts of India, large quantities are consumed by almost all classes of Hindus. The Brahmins sell Sherbet* prepared with Bhang at the temples, and religious mendicants collect together and smoke Ganja. Shops for the sale of pre- parations of hemp are to be found in every town, and are much resorted to by the idle and vicious. Hemp is also used medi- | cinally ; in the Rdja Nirghanta its synonyms are Urjaya and Jaya, names which mean promoter of success, Chépala “the cause of a reeling gait,” Ananda “the laughter moving,” Har- shini ‘the exciter of sexual desire’; among other synonyms are Kashmiri “coming from Kashmir,’’ Matdldni ‘the mater-_ nal uncle’s wife,” Mohini ‘‘ fascinating,” &c. Its effects on man are described as excitant, heating, astringent ; it destroys phlegm, expels flatulence, induces costiveness, sharpens the memory, excites appetite, &c. Susruta recommends the use of Bhang to people suffering from catarrh. In the Réjavalabha, a recent work in use in Bengal, we are informed that the gods through compassion on the human race sent hemp, so that mankind by using it might attain delight, lose fear, and have sexual es The seductive influences of hemp have led to the most extra- vagant praise of the drug in the popular languages of India, but in truth it is one of the curses of the country ; if its use is persisted in, it leads to indigestion, wasting of the body, cough, melancholy, impotence and dropsy. After a time its votary ies av Sabji, an infusion of Bhang with black pepper, anise and “sugar. In Bengal milk, and cucumber and melon seeds are added. i 4 aaa = Bes Pte URTICACER, 301 becomes an outcaste from society, and his career terminates in crime, insanity, or idiotcy. Ganja pie gur-gyan ghate, aur ghate tan andar ka, Khokat, khokat dam nikse, mukh dekho jaisa bandar ka. Who ganja smoke do knowledge lack, the heart burns constantly, The breath with coughing goes, the face as monkey’s pale you see. Fallon. a According to tradition, the use of hemp as an intoxicant was first made known in Persia by Birarslan, an Indian pilgrim, in the reign of Khusru the first (A.D. 531—579), but, as we have already stated, its injurious properties appear to have been _ known long before that date. There can be no doubt that the use of hemp as an intoxicant was encouraged by the Ismailians in the 8th century, as its effects tended to assist their followers ia realising the tenets of the sect :— QSAT ob GHIIUI po 295 eS Se WF Ex) Band gLF Qeh Lyle We've quaffed the emerald cup, the mystery we know, Who’d dream so weak a plant such mighty power could show! Hasan Sabah, their celebrated chief, in the 11th century notoriously made use of it to urge them on to the commission of _ deeds of daring and violence so that they became known as the © Hashshdshin or “ Assassins.”” Hasan studied the tenets of his sect in retirement at Nishapur, doubtless at the monastery noticed by O’Shaughnessy (Bengal Dispensatory), in the following - terms:— “ Haidar lived in rigid privation on a mountain between Nishapur and Rama, where he established a monastery; after having lived ten years in this retreat, he one day returned from a stroll in the neighbourhood with an air of joy and gaiety; on being questioned, he stated that, struck by the appearance of a plant, he had gathered and eaten its leaves. He then led his companions to the spot, who all ate and were similarly excited, A tincture of the hemp leaf in wine or spirit seems to have been the favourite formula in which Sheikh Haidar indulged himself. ; An Arab poet sings of Haidar’s emerald cup, an ey IIl,—41 322 : URTICACE), allusion to the rich green colour of the tincture. The Sheik survived the discovery ten years, and subsisted chiefly on this herb, and on his death his disciples at his desire planted it in an arbour round his tomb. From this saintly sepulchre the _ knowledge of the effects of hemp is stated to have spread into Khoras4n. In Chaldea it was unknown until 728 A.H., the kings of Ormus and Bahrein then introduced it into Chaldea, Syria, Egypt and Turkey.” Taki-ed-din Ahmad, commonly known as Makrizi, who wrote ‘a number of treatises upon Egypt in the 14th century, mentions the lease of the monopoly for the sale of Hashish in that country, and its abolition in (1286) by the Sultan. Haji Zein in the Ikhtiérat (1368), after noticing the two kinds of Kinnab mentioned by the Greeks, states that Indian hemp is known as Bang or Sabz in Shiraz; after describing its properties, he says that in cases of poisoning by it vomiting should be induced by the administration of butter and hot water to empty the stomach, and that afterwards acid drinks should be administered. The Greeks were acquainted with hemp more than 2000 years ago; Herodotus (iv., 74, 75) mentions it as being cultivated by the Scythians, who used its fibre for making their garments, and the seeds to medicate vapour baths. Dioscorides mentions two kinds of «avvdfs, the wild and the cultivated; the former is the Althea cannabina of Linneus, and the latter Cannabis sativa; he states that the seeds, if eaten too freely, destroy the virile powers, and that the juice is used to relieve earache. Galen and the early Arabian physicians, such as Ibn Sina and Riazi, follow Dioscorides in his opinion of the properties: of hemp, and do not notice its having any -intoxicat- ing properties, and unless the Gelotophyllis of Pliny (24, 102) was Indian hemp, there is no evidence to show that the ancients _ were acquainted with them. Pliny says :—“The Gelotophyllis —— leaf) is a plant found in Bactriana, and on the banks sorts a tom Taken internally with myrrh and wine, iL sorts of visionary ee aent themselves, and excite the A ae S ees fers = Sy ee ece ea, A. ee ee URTICACEA, 323 ost immoderate laughter, which can only be put an end to taking kernels of the pine nut, with pepper and honey, in yalm wine.” The earliest Western medical writer who dis- tly mentions the intoxicating properties of hemp is Ibn Baitar, a native of Africa, who died in Damascus in 1248. AIT later Mahometan physicians describe the two kinds of a ana, the Russian Kanopla, the Irish Canaib, the Iceland the Saxon Heenep, and the old German Hanaf. Yundni name, and Kanabira as the Syrian, and also mentions a number of cant terms which are applied to it, such as Wark-el- khy4l, Hashish, Hashishat-el-fukaré, Arsh-num4, Chatr-i-akh- gar, &e. Charas is described, and the practice of smoking it. The Bengal-grown hemp is said to be less intoxicating than that. grown in more Northern climates. Hempseed is called in Per- ‘sian Shahdénah, “royal seeds.” The leaves are made into Sherbet and conserves for intoxicating purposes. The properties of mp are described as cold and dry in the third degree, that iy timulant and sedative, imparting at first a gentle reviving heat, and then a refrigerant effect, the drug at first exhilarates, improves the complexion, excites the imagination, increases the cheea, to the extent of a quarter drachm of bhang. Charas is only mentioned in comparatively recent medical works. The word is said to be derived from the Sanskrit 4a eauthor of the Makhsan-el-Adwiya gives Udifartinas*as the -* Some such word may have been manufactured by the Syrian monks jn the Middle Ages, possibly from é and 8:apepo as an equivalent to the | askrit ‘ Vijaya.’ ihe 324 URTICACEZ. a skin, but it occurs in Persian with the primary signification of a piece of leather or cloth, the four corners of which are tied up so as to form a wallet, such as beggars carry ; in Hindi it signifies a leather bag for holding water, &. The Charas collected in Central Asia is stored in leathern bags by the cul- tivators. Among European writers in the East, Rheede and Rumphius figure and describe the Indian plant ; the latter states that the kind of mental excitement it produces depends upon the temperament of the consumer, He quotes a passage from Galen, lib. I. (de aliment. facult.), in which it is asserted that in that great writer’s time it was customary to give hempseed to the guests at banquets, as a promoter of hilarity and enjoy- ment (the seeds are still roasted and eaten in the East). Rumphius adds, that the Mahometans in his neighbourhood frequently sought for the male plant from his garden, to be given to persons afflicted with virulent gonorrhea or with asthma, and the affection which is popularly called “ stitches in the side.” He tells us, moreover, that the powdered leaves check diarrhoa, are stomachic, cure the malady named Pitao, and moderate excessive secretion of bile. He mentions the use of hemp smoke as an enema in strangulated hernia, and of the leaves as an antidote to poisoning by orpiment. In the Bulletin de Pharmacie (1810, p. 400), we find it briefly described by M. Rouyer, apothecary to Napoleon, and member of the Egyptian Scientific Commission, in a paper on the popular remedies of Egypt. With the leaves and tops, he tells us, collected before ripening, the Egyptians prepare a conserve, which serves as the base of the berch, the diasmouk, and the bernaouy. Hemp leaves reduced to powder and incorporated with honey, or stirred with water, constitute the Jerch of the poor classes, | Ainslie notices Majin, a confection made with hemp leaves to be used as a Sweetmeat, the composition of which varies in different parts of the East, and to which are often added other es drugs. O'Shaughnessy in the Bengal Dispensatory see BAYOR & detailed account of its preparation in Calcutta. URTICACEA. A ., _ The medicinal properties of Cannabis have now been inves- tigated by many European physicians in India. O’Shaugh- nessy tried it with more or less success in various diseases, especially in tetanus, hydrophobia, rheumatism, the convulsions of children and cholera. Subsequent experience has confirmed the value of the drug as a remedy in tetanus and cholera. In the former disease we have obtained most satisfactory results, large doses are required, and the patient must be kept under the influence of the drug for some days. In cholera its action may be compared with that of opium; it is most likely to be successful when resorted to early in the | ‘disease. People suffering from painful chronic diseases, such as rheumatism, are completely relieved of their pains by hemp, but as the effects of the drug go off, the pains return; some of | O’Shaughnessy’s patients became cataleptic whilst under its influence. Christison, speaking of Indian Hemp, says:— **T have long been convinced, and new experience confirms the conviction, that for energy, certainty, and convenience, it is the next anodyne, hypnotic and antispasmodic, to opium and its derivatives, and often equal to it.” Among the “ special opinions”’ collected by Dr. Watt for the Dict. of the Econ. Prod. of India, we observe that Dr. 8. J. Rennie recommends the tincture in doses of from 15 to 20 minims three times a day in acute dysentery, and states that he, as well as other medical officers, obtained excellent results with it. Dr. J. E. T. Aitchison states that the oil of the seeds, known as Kandir yak in Turkistan, is used in Kashmir as a liniment for rheumatic pains. Others notice it as having valuable narcotic, eth and cholagogue properties. (Op. cit., Wol-ii., p. 1 A. Aaronson states in the British Journal of Dental Science, that the tincture as a local anesthetic is perfectly satisfactory. He has extracted with its aid as many as twenty-two teeth and stumps at one sitting. His plan is to dilute the tincture some three or five times, according to the probable duration of the operation. The diluted tincture is then applies on a coe é 326 URTICACEA, wool to cavities, if such exist, and also about the gums of the affected teeth. The beaks of the extracting forceps are also, after being warmed, dipped in the tincture. In cold weather it is best to dilute the tincture with warm water. His patients acknowledge the immunity from pain they enjoyed during the ° operations, and all expressed surprise and pleasure at the simpli- city of the performance. Tannate of cannabin has recently been recommended as a hypnotic. Cannabis appears capable, directly or indirectly, of causing uterine contraction, as in many cases of uterine hemorrhage ; and it is also said to provoke this act during labour with as much energy as ergot, but with less persistant action, A recent correspondence in the Lancet, anent the variation in action and occasional toxic effects of this drug, has brought from Dr. J. Russell Reynolds an important contri- bution respecting its clinical value. In explaining the occasional toxic effects of this drug, Dr. Reynolds says two things must be remembered : first, that, by its nature and the forms of its administration, cannabis indica is subject to great variations in strength. Extracts and tinctures cannot be made uniform, because the hemp grown at — different seasons and in different places varies in the amount of the active therapeutic principle. It should always be obtained m the same source, and the minimum dose should be given at t first, and gradually and cautiously increased. The secon important fact to keep in view is, that individuals differ widely in . their relations to various medicines and articles of diet— to none more than to substances of vegetable origin, us as tea, coffee, ipecacuanha, digitalis, nux vomica, and the like. In addition to the purity of the drug, the possibility of idiosyncrasy must be borne in mind as calling for caution in © giving Indian hemp. By gradually increasing the dose and habituating the organism to its use, the use of cannabis indica may be pushed to 3 or 4 grains of the extract at a dose with posi- tive nena But mers De. eee! experience 1 grain would URTICACEZ. 327 ing about toxic effects in the majority of heel adults ; and of a grain has done the same, but never }, which is the — _ proper amount with which to begin the use of the drug among grown persons, zp of a grain being the proper initial dose for children. The best preparation for administration is the tincture—1 grain to 20 or 10 minims—dropped on sugar or bread. The minimum dose should be given, as before stated, repeated every four or six hours and gradually increased every d or fourth day, until either relief is obtained or the drug is proved useless. With such precautions, Dr, Reyn states he has never met with toxic effects, and rarely failed to ascertain in a short space of time the value or uselessness of the drug. Its most important results are to be found in the mental sphere ; as, for instance, in Senile Insomnia, with wandering. An elderly person (perhaps with brain softening), is fidgety at night, goes to bed, gets up, thinks he has some appointment to keep, that he must dress and go out. Day, with its stimuli and real occupations, finds him quite rational again. Nothing can compare in utility to a moderate dose of Indian hemp at bedtime—} to 4 of a grain of the extract. In alcoholic. sub- jects it is uncertain and rarely useful. In Melancholia it is sometimes serviceable in converting depression into exaltation ; but unless the case has merged into senile degeneration, restlessness of general paretics and of sufferers from the ‘temper disease ” of Marshall Hall, whether children or adults, it has proved eminently useful. In painful affections, such as Neuralgia, Neuritis, and igraine, Dr. Reynolds considers hemp by far the most useful 0 , even when the disease is of years’ duration. In neuritis the remedy is useful only in conjunction with other treatment, and is a most valuable adjunct to mercury, iodine, _ or other drugs, as it is in neuralgia when given with arsenic, — quinine, or iron, if either is required, Many victims of diabo- 328 URTIOACEZ. lical migraine have for years kept their sufferings in abeyance by taking hemp at the threatening or onset of the attack. In sciatica, myodynia, gastrodynia, enteralgia, tinnitus aurium, muscz volitantes, and every kind of so-called hysterical pain, cannabis indica is without value. On the other hand, it relieves the lightning pains of Ataxia, and also the multiform miseries of the’) gouty, sink as tingling, formication, numbness, and other pareesthesize. In clonic spasm, whether epileptoid or choreic, hemp is of the great service. In Eclampsia of children or adults, from worms, teething (the first, second, or third dentition), it gives relief by itself in many cases. Many cases of so-called Epilepsy in adults—epileptoid convulsions, due often to gross organi¢ nerve-centre lesions—are greatly helped by cannabis indica, when they are not affected by the bromides or other drugs. Take, for instance, violent convulsions in an overfed man, who : is attacked during sleep a few hours after a hearty supper, the attacks recurring two or three times an hour for a day or two, in spite of “clearing the prime vie,’’ or using bromine or some other classic drug. These attacks may be stopped at once with a full dose of hemp. In brain tumours or other maladies im the course of which epileptoid seizures occur, followed by coma, the coma being followed by delirium,—first quiet, then violent— the delirium time after time passing into convulsions, and the whole gamut being repeated, Indian hemp will at once cut short such abnormal activities, even when all other treatment has failed. In genuine epilepsy it isof no avail. In cases where it has seemed to do good, the author doubts the correctness of the diagnosis, and suspects organic lesion or eccentric irrita- tion. In tonic spasms, such as torticollis and writers’ cramp, _ in general chorea, in paralysis agitans, in trismus, tetanus, and the jerky movements of spinal sclerosis, cannabis indica has proved absolutely useless, At the same time, it is most valu- _ able in the Nocturnal Cramps of gouty or old persons, in some eases of ic Asthma, and in simple Spasmodice Dys- menorrhea, Thus it will be perceived that for the relief of —_ a from a A curative effect, hemp must ever ioe aie 4S Petes woes. = le SRE ot: ' c e a aay i bites hee aut saad eacten: : Mess : Seaver og - PSE nay, eee aor URTICA 320 : be held in high esteem, and eaiked with the poppy and with mandragora. (Medtcal Annual, 1891.) : Physiological action.—Like some other narcotics, Indian hemp, when given by the stomach to carnivorous animals, produces its characteristic effects, but graminivorous animals and fish exhibit only vacillating movements and a dull aspect. Upon man its — action varies with the individual’s temperament and tendencies, Some it inspires with pugnacity, others it inclines to dreamy contemplation, to motiveless merriment, or to maudlin sensibi- lity ; some it makes unnaturally active and restless, and plunges others in a drowsy stupor ; but more than any other agent, not even excepting belladonna, it perverts the natural perception of objects and their normal condition and relations, Time, dis- tance, and sound are especially apt to form the subjects of the hallucinations caused by this drug. As in dreams, the events of days or weeks may be compressed into an actual period of a few minutes, objects near at hand may seem to form a limitless perspective, and whispered tones may have the reverberation of thunder. These and an infinite variety of fantastic pictures are evoked by smoking the drug, as it is generally employed in _ Asia, associated with opium. During its influence the physical | condition of the experimenter exhibits changes in acceleration of the pulse, warmth of skin, restless muscular movements, more or less insensibility to touch and pain, and sometimes im- paired power of locomotion, the limbs feeling as if weighted with lead. In one reported case a diffused vesicular eruption was attributed to this medicine. (Hyde.) It does not increase, ut, on the contrary, impairs, the venereal propensity and power. The habitual use of cannabis in excessive doses causes the face to become bloated, the eyes injected, and the limbs weak and tremulous; the mind grows imbecile, and ultimately death by marasmus is apt to occur, Acute poisoning by large doses is marked by various and dissimilar symptoms in different cases. In some there is loss of consciousness, with collapse or stupor, insensible pupils, a pale, clammy, and insensible skin, extreme debility, anda small, feeble pulse. In others a catalep~ S tic condition, spasms, or convulsions occur, and in all there i i W1.—42 o 330 URTICACEZ. marked anesthesia. The last-named effect led to the use of cannabis by the Chinese in certain surgical operations. (Stillé and Maisch.) Collection.—The flowering tops of the female plant are collected, and, after having been allowed to wither in the open air for about 48 hours, are arranged on a mat so asto forma circle, and are trodden upon by a number of men, linked together by resting their arms across each other’s shoulders, who walk round and round; the object being to compress the resinous flower tops into a compact mass. This process 18 repeated several times after shifting and re-arranging the Gdénja. In Bengal a round kind of Gdnja is prepared by rolling the flowering tops under the feet, and afterwards between the palms of the hands. During the manufacture of Ganja a quantity of powder separates, which is known as Ohdr or Rora; it is collected, mixed with an extract of the plant, and made into round balls about the size of a musket ball, which are used for smoking like Charas. A similar preparation is made from the dust of the leaves; it is popularly known as Charas ; several varieties of it are foant in the bazars. True Charas is collected in Central Asia by shaking, rubbing, or beating the resinous exudation from the flowering plant; it separates as 4 greyish powder, which, after being packed in bags, gradually consolidates into an oily resinous mass. The genuine article is rarely to be met with in commerce, that sold in the bazars being largely adulterated by the middlemen in the Punjab with the leaves and dust of Bhang. Bhang is made by collecting the leaves and drying them. All of these drugs are obtained from the female plant, which the natives consider to be the male, because it bears the seed ; all male plants are carefully extirpated by the hemp doctor, a person whose business it is to prune the plants so as to produce the maximum amount of flowering heads, Description. —Bhang consists of the dried leaves, which are of a deep green colour and Suk, broken, so as to form 4 coaee a se iar. The deoton have long OS Gee URTICACER. 331 petioles and are digitate, with linear-lanceolate, sharply serrated leaflets, tapering to a long smooth point. _ Ganja is the name given to the flowering tops of the female plant. The flowers form erect clustered spikes, often 6 to 8 inches long; in the drug, the spikes are compressed, flat or round, glutinous, and of a brownish-green colour; they have a peculiar narcotic odour. = Pure Charas is a greenish-brown, moist, resinous mass, mixed with the hairs and fragments of the leaf. Bazar Charas aries much in quality, some specimens being only very rtially soluble in spirit, friable, and of an earthy appearance. Sixty grains of the finest Yarkand Charas which we examined left, after exhaustion with spirit, only 13 grains of residue, chiefly hairs of the plant. Chemical composition.— The most interesting constituents of hemp, from a medical point of view, are the resinand the vola- tileoil. The former was first obtained in a state of comparative purity by T. and H. Smith in 1846. (Pharm. Jouwrn., vol. vi., p- 171.) It is a brown, amorphous solid, burning with a bright white flame, and leaving no ash. It has a very potent action when taken internally, two-thirds of a grain acting as a power- ful narcotic, and one grain producing complete intoxication. - When water is repeatedly distilled from considerable quan- tities of hemp, fresh lots of the latter being used for each opera- tion, a volatile oil lighter than water is obtained, together with ammonia. This oil, according to the observations of Personne (1857) (Journ. de Pharm., vol. 39, p. 48), is amber- coloured, and has an oppressive hemp: like smell. It sometimes deposits an abundance of small crystals. With due precautions it may be separated into two bodies, the one of which named by Personne Cannabene, is liquid and colourless, with the formula C'8H2°, the other, which is called Hydride of Cannabene, is a solid, separating from alcohol in platy crystals, to which has indubitably a physiological action, and even clas it as” Personne assigns the formulaC'® H**. He assertsthat cannabene s 332 URTICACE #, sole active principle of hemp. Its vapour he states to produce, when breathed, a singular sensation of shuddering, a desire of locomotion, followed by prostration and sometimes by syncope. hling, in 1840, observed similar effects from the oil, which he obtained from the fresh herb just after flowering, to the extent of 0°3 per cent. As to the resin of Indian hemp, Bolas and Francis, im _ treating it with nitric acid, converted it into Oxycannabm, O°°H2°N°O’, This interesting substance may, they say, be obtained in large prisms from a solution in methylic aleohol. ; It melts at 176°C., and then evaporates without decomposition; = it is neutral. (Pharmacographia.) 2 Preobraschensky (Pharm. Zeitsch. f. Russland, 1876, : p- 705) made a chemical examination of a quantity of haschiseh, which he brought with him from China, and was enabled, according to his own statement, to separate from it a volatile alkaloid, which he held to be identical with uicotine, and which he believed to be the active principle of cannabis. This, in view of the distinctive and very different action of cannabis, - was somewhat remarkable. It is highly probable, as has been suggested by Dragendorff and Marquiss (Pharm. Zeitung, 1877), = that the haschisch used by Preobraschensky was mixed with ; tobacco, which it often is in Eastern countries. Louis Siebold and Bradbury reported to the British Pharma- ceutical Conference (1881) that, after an elaborate investigation, _ they had arrived at the conclusion of Dragendorff and Se a. and that in the course of their investigation they ng not more than Q grains from 10 Ibs. of an hemp. _ They give it the name of Cannabinine. They t cdaten as to its physiological action; and they, leave it doubtful as to whether this. volatile alkaloid iple of — as - wiapaiae ” SS hee Oe oe en STATE ae Geen eee * URTICACEA#. 383 Dr. Hay (Pharm. Journ., xiii., p. 998) made a chemical examination of the drug, the results, so far, of which lead him to believe that Cannabis indica contains several alkaloids. He says: —“In a future. communication [ hope to be able to give an exact description of the distinctive characters and toxic action of each, In the meantime, I shall content myself with the description of one which I have obtained in a consi- derable degree of purity, and one which, rather remarkably, __ possesses an action similar to that of strychnia. It is evidently, therefore, quite a secondary alkaloid of the cannabis, and reminds one of the thebaine of opium. This alkaloid was obtained from a watery infusion of powdered Cannabis indica by treating it with a solution of subacetate of lead, and filtering. To the filtrate was added ammonia, and the precipitate removed by ‘filtration. The filtrate, acidulated with sulphuric acid, was now treated with a solution of phospho-wolframic acid in order to precipitate the alkaloids present. The precipitate, which was fairly abundant, was, after the fluid had been removed by filtration and washing with dilute sulphuric acid and pressing, mixed with barium hydrate and water, which formed an insoluble wolframate and set free the alkaloids. The filtrate was next deprived of its excess of barium by means of a stream of carbonic acid gas and again filtered. The filtrate was ata gentle heat evaporated almost to dryness and acidulated with sulphuric acid, and treated with absolute alcohol. The sulphate of the alkaloids thus formed was partially soluble in alcohol, partly not. It was from the soluble part that the alkaloid in question was procured. The sulphate was converted into a chloride by treatment with barium hydrate, afterwards with carbonic acid to remove excess of barium, and, finally, with hydrochloric acid to neutralization. Thechloride was evaporated and treated with absolute alcohol, in which it in part dissolved, From the solution, by addition of excess of carbonate of soda and frequent shaking with ether, an alkaloid was obtained in the form of colourless needle-like crystals. “The alkaloid was easily soluble in water, soluble also in alcohol, and more slowly soluble in ether and chloroform. It 8334 URTICACE. caused tetanus in frogs in exactly the same manner as strychnia, increasing the excitability of the reflex centres of the spinal cord. It did not give a violet colour with sulphuric acid and bichromate of potash. It was, therefore, although similar in action to strychnia, not chemically identical with it. A solution of it in water was precipitated by the various alkaloidal precipitants, platinic chloride, iodide of potassium and mercury, phosphotungstate of soda, phosphomolybdic acid, phospho- wolframic acid, &. Although I obtained the alkaloid from ~ 1 kilo. of cannabis, yet the quantity of it was so small that it was insufficient for an elementary analysis. “To this alkaloid I propose to give the name of tetano-canna- bine, as indicative of its action.” The Tannate of Cannabin of Merck (Pharm. Jour., xiil., p- 1052), a glucoside contained in Indian hemp, which he has combined with tannin, is a yellowish-brown powder, with a taste of tannin, and a rather agreeable odour ; it is insoluble in water and ether, and only slightly soluble in alcohol ; in alkaline solutions it dissolves readily. This substance is said to be free from any admixture of the volatile alkaloid of Cannabis indica, not to produce intoxication, and to be useful as a hypnotic; it is said not to derange the digestive and secretory organs like opium, and to be especially valuable in irritable states of the nervoussystem, but Dr. H.C. Wood has found it to be inert physiologically, Warden and Waddell of Calcutta, although operating on a large quantity of Indian hemp of ascertained activity, were unable to find any evidence of the existence of such a principle as Dr. Hay describes. They further remark that :— “ As many of those addicted to the Hashish form of intemperance obtain the intoxicating — _ effects by smoking the plant in a pipe, it is to be expected - that destructive distillation of the freshly prepared resin might yield up the active principle. This process was therefore resorted to. By the destructive distillation of freshly prepared alcoholic extract of the plant to which an excess of caustic _ potash solution had been added, an amber-coloured oil was obtained, which, oe osure ue oe tor the action of alkalies, OM ee te se yee a URTICACE®. 335 _ rapidly became of a dark reddish-brown colour, This oil had a mildly empyreumatic odour, which was distinctly tobacco-like. Its taste was warm, aromatic, and somewhat terebinthinate. — _ he oil contained phenol, ammonia, and several other of the usual products of destructive distillation. “ The nicotine-like principle contained in this oil appeared to be an alkaloid. It formed salts which evolved a strong _ nicotine-like odour when acted on by alkalies. But physiologi- _eally it was found to be inert, and therefore was evidently not identical with nicotine. “The oil as a whole was also found to be devoid of any narco- _ tic or irritant qualities. About 3 of an ounce was introduced 2 into the stomach of a cat without producing any sensible ‘effect. These results do not coincide with those of Personne, who asserted that the active principle of the plant resided in the volatile oil. It is just possible that the active principle was decomposed by the high temperature necessary for destruc- tive distillation.’ (Ind. Med. Gaz., Dec. 1884.) _ Kennedy (Pharm. Record, vi., p. 304) made a search for ectine in Indian hemp without success, but obtained indi- - eations of the presence of another alkaloid. E. Jahns (Archiv. d. Pharm., 1887) reported that he had separated from Indian hemp a base which he has identified as choline, and points out that this result corresponds fairly with the statement of previous workers, except in respect to the erys- tallizability of Dr. Hay’s alkaloid and solubility in ether. The quantity of choline obtained by the author from different 3 opie varied considerably, but amounted at the most to _ only +5 per cent. Hi. F. Smith (Amer. Journ. Pharm., Aug. 1891), by deceit different processes, obtained an alkaloid from Indian hemp, which separated from ethereal solutions in the form of a yellow- ish-green, transparent varnish-like substance. It had a strong, peculiar odour, resembling that of coniine ; was soluble - inether, chloroform, alcohol, and acidulated water, but onl: . slightly so in water ; was alkaline to test paper and capab 336 URTICACER. neutralizing acids. When dissolved in very dilute H*SO* (1 gtt. in 5 cc.), it gavea clear yellow solution and the following reactions :— With Mayer’s reagent, an abundant white precipitate. KI+1+H°O, an abundant brown precipitate. ,», Phosphomolybdate of soda, an abundant white precipi- tate ,, Solution of picric acid, an abundant yellow precipitate, K*C*0’, a yellowish-brown precipitate. a % NH?‘OH, a yellowish-green precipitate. NaOH, a yellowish-green precipitate. _ KOH, a yellowish-green precipitate. = = KI, a yellowish precipitate. tannic acid, a yellowish-brown precipitate. Biondaiig this alkaloid of Indian hemp to be highly poisonous, it is present in so small a quantity as to be of little if any importance therapeutically. Toxicology.—Lyon says—‘‘ In India, Cannabis appears to be seldom, if ever, used for homicidal purposes. Fatal, accidental or suicidal cases have, however, been reported. Cases have also been reported where the drug has, or appears to have, been used for the purpose of facilitating the commission of an offence. Thus Chevers mentions a case which occurred at Ahmednagar, in which a woman, having first drugged with majun, a child aged seven, afterwards murdered him for the sake of his ornaments. (Med. Jurisp., p. 225.) Harvey reports a case in which charas appears to have been used by a road-poisoner at Amritsar, in order to facilitate theft. (Beng. Med. Leg. Rep., 1870-72, p. 268.) A case is also reported by Dr. Cullen of Hoshangabad, in which majun was given to a woman and her daughter, “not with the inten- tion of causing death, but to effect a criminal purpose.” In these two females, the symptoms present exactly resembled those of dhatura-poisoning, and it would appear that dhatura S soa fe as an ingredient of majun. (Lyon, Med. bed yoy Pe COV.) - Sooten Hage Ganja is epee used as a poison in Coe, ate V admr1 uy admin with criminal ne In sr ] 3 URTICACEZE, 337 a case of dacoity investigated near Madura in 1886, it was found that ganja had been given in food served up to some travellers. It is resorted to by the relatives of converts to Christianity in Travancore, to prevent them changing their religion or to punish them for doing so. Dr. Hové, a Polish savant, who was sent out to Bombay by the British Government in 1787- 89, speaking of Cannabis, says _ (p. 141): “I arrived at Mithampoor and waited on the Rajah, who ordered provisions for my people and guards. He also _ ordered to each person a basinful of a beverage which _ iscalled by the inhabitants Beng. This is nothing else but a decoction of seeds, and bruised leaves and stalks of the Cannabis, which has, however, such powerful quality, that even _ the steam where it was served overpowered me in a few tes, so that I was under the necessity of leaving the room.” We have no doubt that Cannabis is much more frequently used in India for drugging people than is generally known. Commerce.—The sea-borne trade in preparations of hemp is ~ insignificant; a small quantity of ganja goes to Europe for — medicinal use. The imports by trans-frontier routes do not — exceed 2} lakhs of rupees yearly, and the exports 20 to 20 _ thousand rupees. As regards internal trade, the total annual revenue transactions (transfers, &c.) amount to about 15 lakhs of rupees. The wholesale cost of ganja duty-free is about 4} annas per lb., und of dhang, Rs. 8 per ewt. The revenue realised by the Indian Government by the duty on hemp is about 30 lakhs of rupees yearly. For full particulars of the Hemp trade in on see Dict. Econ. Prod, of India, ii., op Lys. FICUS RELIGIOSA, Lin». : Fig.—King, Fic. 55, t=. 67 A, 84u; Wight Ic., t. 1967 ; Rheede, Hort. Mal. i., t. 27. Hab.—lIndia. The root-bark. IlT.—~43 338 URTICACE &. FICUS BENGALENSIS, Linn. Fig.—ing, Fic. 18, ¢, 31, 8le; Wight Ic., t.1989 ; Rheede, Hort. Mal, 1., ¢. 28. Hab,—India. The root-bark. FICUS TJAKELA, Burm. Fig.—King, Fic. 57, t. 70, 84x; Rheede, Hort. Mal. iit., t. 64. Hab.—India. The root-bark. FICUS GLOMERATA, fozxb. Fig.—forb. Cor. Pi. ii., t, 123; Wight Ic., t. 667. Hab.—India. The root-bark, fruit, juice, and galls. Vernacular.—F. religiosa, Pipal, Pipar (Hind., HMar., Guz.), Aswat, Asud (Beng.), Arasa (Tam.), Rai, Raiga (Ze/.), Rangi, Basri (Can.). F. bengalensis, Bar, Bargat (Hind., Beng., Guz), Vara, Vari (Mar.), Ala (Tam.), Mari, Peddi-mari (Te/.), Alada- _mara (Can.). F. Tjakela, Ram-anjir, Pakhar (Hind., Beng.), Bassari, Pakri, Lendva (Mar.), Jovi (Tam.), Jevi (Tel.), Kari, Bassiri (Can.) F. glomerata, Gtlar, Umar (Hind.), Jagno- dumar (Beng.), Atti (Tam.), Moydi, Atti (Zel.), Kulla-kith (Can.), Umbara (Mar.), Umbro (Guz.). History, Uses, &c.—In the Kéthaka Upanishad an eternal and cosmogonic ASvattha or Pippal tree is described ; this tree is said to have its roots above and branches below (ardhyamilo’ yékSakha esho’ Svatthah sandtanah) ; it bears the names of ‘seed,’ ‘ brahman,’ ‘ amrita’; the worlds rest upon it; beneath it there is nothing. The wood of the Aévattha when rubbed against that of the Sami (Acacia Suma) engenders fire, which is symbolic of reproduction, the former representing the male and the latter the female energy. At the marriage ceremony of the Hindus, both of these plants are necessary. To this mythic tree which represented the macrocosm, wonder- ful medicinal properties are ascribed in the Atharvaveda ; the medicine chest of — Neti 2h rae and the cup to contain URTICACEA. 339 th Saori, are to be made of it ; its branches are the Vedas. In the Vilakhilya, a collection of apocryphal hymns in the Rig- veda, the marriage of the actual tree with Tulasi is enjoined; it worshipped on eavarenys in the month of Sravan and on Somvatis or “lunar days.’ Women perform Pradakshina, “walking round it from left to right,’? to secure the survival of eir husbands and good luck generally, as Savitri, the wife of ity van, is said to have recovered her deceased husband by its The thread ceremony and marriage of the tree with e Budhidru, or tree of wisdom, of the Jains and Buddhists, who late that at the birth of the Buddha an enormous ASvattha sprung from the centre of the universe, an offshoot, no doubt, of the Vedic and cosmogonic tree. In the kia Nirghanta it bears the synonyms of Y4jnika “ sacrificial,” Srimana “ fortunate,” Vipra “ wise,” Sevya “ worthy of worship,” &c. Its root-bark, together with that of the three other species of Ficus placed at the ] of this article, and the root-bark of the Neem, form the Panchavalkala or ‘ five barks,” and a decoction of them (pancha- — la kashéya) is much used asa gargle in salivation, as a h for ulcers, and as an astringent injection in leueorrhea. The powdered root-bark of the ASvattha, rubbed with honey, is applied to apthe and unhealthy ulcers to promote granulation. F. bengalensis, the Vata or Nyagrodha, has been sometimes omnfounded with the Asvattha; both trees bear the synonyms ahupada “many-footed,” and Sikhandin “ crested,” but the Vata is specially described as Skandaja “ born of the trunk,” Ava-roha- Sayin “‘sending down branches,” Skanda-ruha “ grow- ing from its own trunk,” Pada-rohana, &c. In Indian mythology an enormous Vata tree is supposed to grow upon mount Supérsva, to the south of the celestial mount Meru, and to cover eleven yojanas; in the Vishun Purana we find a similar account of the Pippala growing on mount Vipula and _ covering eleven hundred yojanas. Devaki, when pregnant with _ Kansa, who had destroyed her first six children. The tree Krishna, is said to have taken refuge under a Vata tree from ee 340 URTICACEZ. special favorite of the Buddha, and Arrian speaks of the Indian sages as sitting under it. There is one famous tree mentioned in the Ramayana, the Uttara Rama-charitra, the Kurma-purana, and elsewhere, which still grows on an island in the Nerbudda ; it is said to have been planted by the sage Kabira some two thousand years ago, and is popularly known as the Kabir Bar, Owing to the peculiar growth of these trees, there is no reason why they should not last for an mdefinite period. _ The figs of the Udumbara (F. glomerata) are considered to be astringent, stomachic and carminative, and are given in menorrhagia and hemoptysis, in doses of one tolaof the dried fruit with sugar and honey. The fresh juice of the ripe fruit is used as a vehicle (Vern. atqm)-for metallic preparations. The juice of the root is used as a tonic, is applied to glandular _swellings,* and is given in doses of four tolas with cumin and sugar in gonorrhea. The small blister-like galls, which are common on the leaves, are soaked in milk and mixed with honey asaremedy for pitting. in small-pox. This tree bears the synonyms of Yajniya “sacrificial,” Pavitraka “ purifier,” &., and is much used in Hindu ceremonial. According to the Grihya Sutra, a married woman in the fourth month of preg- nancy should be rubbed with the fruit to fortify the germ. eS Tjakela, in Sanskrit Parkati or Parkatin, SupdrSva and Plaksha, is the waved-leaved fig-tree, a sacred tree, but of minor importance. It is the Tsjakala of Rheede. Mahometan and European writers do not add much to our knowledge of the medicinal properties of .these trees. Ainslie, speaking of F. glomerata, says:—‘ From the root of the tree, _which in Tamil is called attievayr, there exudes, on its bemg eut, a fluid, which is caught in earthen pots, and which the Vytians consider as a Cilpim (Zam.), that is, a powerful tonic, when drank for several days together. This Ciilp4m is termed attie-oayr tannie.” (Mat. Inds is p. 30. - ™* Ibis interesting to ms that the jui epnohtts of Binecighinpe nd the Teall i aby a eed re Sukex Savi is still used in pt for a similar d that both ‘The In pita the same e »i, 148, and a Prosper 4p inus, ps) 2). ee n rae as a substitute for 8 Ainslie also states that the seeds of F. religiosa are supposed to possess cooling and alterative qualities, and quotes the follow- ing passage from Bartolomeo’s Voyage to the Kast Indies : “ Pul- rised, and taken in water for fourteen days together, poi fruit removes asthma, and promotes fruitfulness in women.” The tree is the Aveddu of Rheede, and the Arbor conciliorum of Rum- us. (Mat. Ind., ii., p. 25.) dy for toothache, and to the soles of the feet when cracked Esflamed. The leaves, after they have turned yellow, are n in the Concan with roasted rice in decoction as a diaphoretic ; dose, three leaves. Description.—F. redigiosa, a tree.— Leaves long-petioled, ovate, cordate, narrow acuminate, acumen one-third the length of the leaf, entire, or repandly undulated towards the apex ; fruit-receptacles axillary, paired, sessile, depressed, size of a small cherry, appearing in the hot season and ripening in the rainy season, purple when ripe. __F-. bengalensis, a tree.—Branches spreading very much ; lower ones rooting ; leaves alternate, ovate, bluntly acuminated, with arallel nerves, paler underneath, entire, downy when young, afterwards smooth; fruit-receptacles axillary, paired, sessile, as _ large as a middle-sized cherry, appearing and ripening in the _ hot season, red or yellow when ripe. _F. Tjakela, a tree.—Leaves rather long-petioled, mem- branaceous, oblong, or sublanceolate-oblong, moderately and acutely acuminated, obtuse or rounded, or subcordate at the base, quite entire, or very slightly repand ; fruit small, sessile, in, globose, smooth, when ripe white. F. glomerata, a tree.—Trunk crooked, thick, bark of a rusty- greenish colour, rough; leaves alternate, petioled, oblong oF broad lanceolate, tapering equally to each end, entire, very slightly 3-nerved, smooth on both sides; racemes compound or panicled, issuing immediately from the trunk or large clothed with soft down, purple when ripe. For a URTICACEE. aa white glutinous juice of /. dengalensis is applied as a - / ae branches; fruit pedicelled, nearly as large as the common pie! 2 342 URTICACEA. botanical account of the Genus, the reader is referred to Dr, G King’s ‘ Species of Ficus.” Chemical composition.—The bark of F. religiosa contains 3-8 per cent. of tannin, that of F. racemosa 14:1 per cent., and that of Ff, bengalensis 10-9 per cent. The air-dried bark of F. racemosa yields 12-2 per cent. of ash, that of F. bengalensis 8-05 per cent., and that of F. religiosa 11:7 per cent. The tannin gives a green precipitate with ferric salts. There is nothing else of interest in these barks, except caoutchouc and wax. FICUS CARICA, Linn. Fig.— Woodv., t. 244; Steph. & Ch., t. 154; Reich. Ic. Fl. Germ. xit., t. 659, The Fig (Eng.), Figue (J’r.). Hab.—Persia. Cultivated in India. The fruit, Vernacular.—Anjir (Hind., Guz., Mar., Beng.), Shimai-atti, Tén-atti (Zam.\, Shima-atti, Téne-atti ( Te/.), Shime-atti ( Can‘). History, Uses, &c.—The Fig holds much the same place in the mythology of the West as the Pipal and Bar do in Indian mythology. It has been regarded from prehistoric times as an anthropogonie tree and valued for its nutritious fruit. It is frequently mentioned in the sacred books of the Hebrews and by early Greek and Latin writers. Hippocrates notices it in several places as having aperient, emollient and nutritious properties, and as being useful as an article of diet in phlegmatic affections. Figs were used in lustration by the Greeks. The celebrated Ficus ruminalis of Rome, appears, like the Indian Asvattha (I. redigiosa), to have been regarded as a cosmogonic tree. Pliny gives the following description of it:— *“‘ Colitur ficus arbor in foro ipso ac comitio Rome nata, sacra fulguribus ibi conditis. Magisque ob memoriam ejus que nutrix fuit Romuli ac Remi conditoris appellata, quoniam sub ea inventa est lupa infantibus preebens rumen (ita enim vocabant mammam), miraculo ex acre juxta dicato, tamquam in comitium sponte transisset.”” In the worship of Dionysus, the fig played an important part; the phallus was made of its wood and the URTICACE®. 343 was a necessary offering to the god. In the early Chris- ian mythology this phallic tree became accursed, the tree of fudas, &c., and was supposed to be haunted by evil spirits, and early Italian missionaries in India gave the name of albero ' diavolo to the Indian fig-tree. For a full account of the s and superstitions connected with the fig, we must refer geader to De Gubernatis. (Myth. des Plant., ii., 137—143.) ig appears to have been known to the Arabs and Persians prehistoric times. Aitchison (Botany of the Afghan Delimi- Commission, Trans. Lin. Soc.) gives an interesting account the wild fig-tree of Eastern Persia, and Abu Hanifeh, author e Book of Plants, describes the fig as wild in the Sarah, nd commonly eaten by the people in its fresh state, and also e” (uV!), it is mentioned along with the olive. God, say the commentators, swears by these two fruits, because of their great uses and virtues, for the fig is wholesome and easy of di estion, and medicinally good to carry off phlegm, and gravel the kidneys or bladder, and to remove obstructions of the er and spleen, and it cures piles and the gout, &c. _ The cultivation of this tree in India was introduced by the thometans, and is now carried on by both Mahometans and Hindus in many parts of the country ; caprification is not practised, and all the fruit which we have seen is much inferior to that grown in Kurope. Two varieties, the purple and the : green, are cultivated in the Bombay Presidency, where the area under fig cultivation is about 300 acres ; the Hindus are Dried figs were brought to India from Arabia and Persia, long before the tree was cultivated in the country, by the early Arab traders to the Western Coast, and overland from Persia ; they are of a small kind, pressed flat and strung upon a string made of camels’ hair ; when well washed and stewed in syrup 344 URTICACHKA they are not unpalatable. We have frequently used them for the preparation of confection of senna with satisfactory results. Description.—A fig consists of a thick, fleshy, hollow receptacle of a pear-shaped form, on the inner face of which grow a multitude of minute fruits. This receptacle, which is provided with an orifice at the top, is at first green, tough and leathery, exuding when pricked a milky juice; on maturity it becomes soft and juicy, and the milky juice is replaced by @ saccharine fluid. The orifice is surrounded, and almost closed by a number of scales, near which, and within the fig, the male flowers are situated, but they are often wanting, or are not fully developed. The female flowers stand further within the receptacle, in the body of which they are closely packed ; they are stalked, have a five-leafed perianth and a bipartite stigma. The ovary, whichis generally one-celled, becomes when, ripe; minute, dry, hard nut, popularly regarded as a seed. (Pharma- cographia.) Chemical composition.—Exclusive of the achenes, which, together with the cellular tissue, Bley (1831) found to consti- tute about 15 per cent. of the weight of figs, he obtained 16 per cent. of water, 62°5 per cent. of sugar (glucose), the re- mainder being gum, fat, and saline constituents. The mean of five analyses of dried figs reported by Kénig affords the the following percentage results :-— Water P Fe 8 Albuminoids 4°01 Su gar BS 49°79 Ash 2°86 The anhydrous figs contained -92 per cent, of nitrogen and 2 26 per cent. of sugar. A. Hansen in 1886 found that the latex of Ficus Carica contained principles capable of effecting four fermentative changes ; they peptonise albuminoids in the presence of either lies or acids, act on starch like diastase, and coagulate the casein of te The Products of. digestion are the same as with. h the tw Hmofenpionts are not identical In 1890, URTICACEA. 345 __ U. Mussi separated from fig sap a digestive ferment which he named ‘‘cradina,” from krade (xp45), the name given by the Greeks to the part of the fig with which they associated the digestive property. It contains nitrogen, and differs from pepsin in maintaining its digestive power in an alkaline liquor, and from papain or papayotin in being insoluble in water, not precipitated from solution by alcohol or lead acetate, and. in its activity not being diminished in the presence of hydro- chloric acid. The following species of Ficus are also considered to have medicinal properties :— Ficus Rumphii, B/. King Fic. 54, ¢, 673, 84t; Waghé _ Ie., t. 640,—Pakar (Hind.), Gai-asvat (Beng.), Pair, Ashta _ (Mar.), a native of the hill slopes of North-Western and Central India, isa tree having much the appearance of the Pipal ; leaves on very long petioles {6 to 8 in.), broad-cordate, with a 3 short and sudden acumination, rather membranaceous with __ waved margins, finely reticulated beneath, perfectly smooth ; fruit paired, sessile, round, smooth, black, of the size and appearance of a black cherry. The juice is used in the Concan to kill worms, and is given internally with turmeric, pepper and ghf, in pills, the size of a pea, for the relief of asthma; it causes vomiting. The juice is also burned in a closed vessel with the flowers of Mudar, and four gunjds’ weight of the ashes mixed with honey is given for the same purpose. _ Ficus retusa, Linn. King Fie. 50, ¢. 61, 62, 84p; Wight Ic., t, 642,—Kamrup (Hind., Beng.), Yerra-juvi (7e/.), Pilaka (Can.), Jili (Tam.), Nandruk (Mar.), a native of the base of the Eastern Himalaya and of the Deccan Peninsula, is used medi- cinally in rheumatism, the leaves and bark being pounded and applied as a poultice. In the Concan the following prescription is in use for flatulent colic :—Take of Nandruk leaf-juice, Tulsi leaf-juice, and ghf, equal parts; boil until all the water has evaporated ; do this again 21 times with fresh quantities of the juice of the two plants ; the residuum may then be applied to the belly, and fomentation with a hot brick be pretieesy ae Ill, —44 346 URTICACEHA, Rheede notices a similar use of the plant. (Hort. Mal., iii, t. 55,) The juice of the bark has a seen in liver disease; dose, 1 tolain milk, Ficus asperrima, Roxb. Wight Ic., t. 633,—K4l-umar (Hind.), Kara-karbuda (Te/.), Khargas (Oan.), Kharvat, Kharoti (Mar.), a native of Central India and the Deccan Peninsula, remarkable for the roughness of its leaves, which are used a8 — sand paper by the natives, and have been given the name of — Folhas da raspa by the Portuguese, is a small tree with ovate, alternate, very rough leaves of a pale green colour, at the apex of the petiole and in the axils of the leaf-veins there are small shining green glands asin F. hispida, except that the glands are more completely in the axils, and appear closed, whereas in the latter plant they have a distinct stoma. The leaves owe their roughness to the presence of calcareous hairs. Both the juice of the plant and the bark are well-known remedies for - glandular enlargements of the abdomen, such as liver and spleen. Rheede says that the root taken in the morning with palm vinegar “viscerum ardorem compescit.” The bark is brown, scabrous and brittle, and has a bitter and ater taste. Chemical composition—The bark contains a orystellial principle soluble in alcohol, which is precipitated by alkaloidal reagents, and is not coloured by the stronger acids. It also contains an organic acid precipitated by gelatine, and darkened in colour by ferric chloride. The ash of the air-dried bark afforded 18-4 per cent. of white calcareous ash. Ficus hispida, Linn. Wight Ic., tt. 638, 641, the rE demonum of Kenig, is the Kakodumbara or Kakodumbarika, “ erows’ fig,” of Sanskrit writers, and is stated in Madanpal’s Nighanta to have the same properties as F. glomerata, It is the Két-gular of Hindustan, the Kako-dumar of Bengal, the Bokhera or Dhed-umbar of Bombay, and the Pe-attis of Madras. Rheede says that the fruit boiled in goat’s milk is used in hepatic obstruction ; it has been brought to notice by Mr. x Sheriff on account of its: emetic ae. The shrub has URTICACEZ. 347 opposite, cuneate, oblong leaves, which are scabrous above and downy beneath. The fruit is like a small fig and very downy ; it usually grows from the stem near or beneath the ground ; an interesting description of it by Dr. G. King forms one of the series of Scientific Memoirs by Medical Officers of the Army of India, published at the Government Printing Press, Calcutta. In Bombay and the Concan the powdered fruit heated with a little water is made into a dep, or poultice, __ which is applied to buboes, which it either disperses or brin rapidly to maturity. The fruit is also given to milch-cattle to dry up their milk. The emetic properties of the plant are due to the presence 5: saponin. Chemical composition —The bark contained 2°1 per cent. of tannin, and some wax and caoutchouc-like substance. No alkaloid was discovered, but a glucosidal principle, having the properties of saponin, was separated from a decoction by barium hydrate. The air-dried bark yielded 13°6 per cent. of mineral matter on incineration. Ficus gibbosa, Bi. King Fic. 4, t.2; Wight Ic., t. 650, is a native of the bases of the hill ranges throughout India. It is a climbing shrub, and often a tree with a stem as thick as a man’s arm ; leaves alternate, very shortly petioled, some- what ovate, suddenly acuminated, very unequally sided, cuneate toward the base; lateral nerves 8 to 4 on each side, prominent, spreading, uniting in arches, pale green, rough, length 3 to 4 inches, sometimes a little toothed on the margin; fruit small. The Flora of British India describes four varieties of this plant. In Western India the root-bark is considered to be stomachic and gently aperient. The Marathi name is Dantira, the Telugi names Konda-juvi and Tella-barinka. ay Vat ie ees Reeth eas RS ac 52 ae ee eh el pee oe AA kr ieee a ste Bah: a Ga : Me itr ah she Be oe aa Chemical composition—The bark contains 4°3 per cent. of tannin ; besides some colouring matter, a small quantity of an alkaloidal principle was separated from the tincture, having no very characteristic reactions with the strong acids, The ash of the air-dried bark was 15 per cent, oe 348 -URTICACEZ:. ANTIARIS TOXICARIA, Lesch. Fig.— Bot. Mag. i., t. 17; Wight Ic., t. 1958; Bedd. FV. Sylv., t.307, The Upas tree (Hng.), Antiar vénéneux (Fr.). Hab.—The Deccan Peninsula, Ceylon. The nuts. Vernacular.—Chéndul, Chandakuda, Sépsind{ (Mar.), Nettavil-maram (Tam.), Jajhugri (Can.), Araya-angeli (Jfal.). History, Uses, &c.—‘‘Most exaggerated statements respecting this plant were circulated by a Dutch Surgeon about the close of the last century. The tree was described as grow- ing in a desert tract, with no other plant near it for the distance of 10 or 12 miles, Criminals condemned to die were offered the chance of life if they would go to the Upas tree and collect some of the poison. They were furnished with proper directions, and armed with due precaution, but not more than two out of every twenty ever returned. The Dutch Surgeon Foersch states that he had derived his information from some of those who had been lucky enough to escape, albeit the ground around was strewn with the bones of their predecessors; and such was the virulence of the poison, that “ there are no fish in the waters, nor has any rat, mouse, or any other vermin been seen there ; and when any birds fly so near this tree that the effluvia reaches them, they fall a sacrifice to the effects of the poison. Out of a population of 1,600 persons, who were compelled, on account of civil dissensions, to reside within 12 or 14 miles of the. tree, not more than 300 remained in less than two months, Foersch states that he conversed with some of the survivors, and pro- ceeds to give an account of some experiments that he witnessed — with the gum of this tree, these experiments consisting prin- -cipally in the execution of several women, by direction of the Em- peror! Now, as specimens of this tree are cultivated in botanic gardens, it cannot have such virulent properties as it was stated to have; moreover, it is now known to grow in woods with other trees, and birds and lizards have been observed on its —_—- Y grows in certain low yalleys in Java, rend a Se et — from crevices in URTICACEZ. 349 the ground, and which is given off in such abundance as to be fatal to animals that approach too closely. These pestiferous valleys are connected with the numerous volcanoes in the island. The craters of some of these emit, according to Reinwardt, sulphureous vapours in such abundance as to cause the death of great numbers of tigers, birds and insects; while the rivers and lakes are in some cases so charged with sulphuric acid, that no fish can live in them.” (Treasury of Botany.) - In Travancore A. toricaria is known as the sacking tree, and is not regarded by the natives as poisonous; the same is the case in Coorg, where sacks and even garments are sometimes made from the inner bark. In the Concan and in Canara the bitter seeds are used as a febrifuge, and as a remedy in dysentery, one-third _to one-half of a seed being given three times a day. The use in the Malayan region of a vegetable poison to tip the bamboo arrows which are discharged from a blowpipe, is too well known to need description. To this the name Upas is given in Java, and Ipoh by the Malays elsewhere. Both words have the same meaning, and, according to Blume, signify poison, ‘There is no doubt that this poison isthe produce of A. toxicaria. In 1878, Regnault experimented with a poison used by the savages of Tonkin to poison their arrows, and in a communication to the Société de biologie he showed that this substance was a powerful heart poison. Baillon identified the leaves from which the poison was prepared as those of A. toxicaria. In 1881, Sir Cecil Smith, then Colonial Secretary to the Straits Settlements, forwarded to Kew a bottle of Ipoh poison as well as foliage specimens of the tree from which it was obtained. These were collected by Sir Hugh Low, then British Resident in Perak, at the Plus River. The poison was subjected to a careful examination by Dr. Sidney Ringer, who reported that it was perfectly inert. The plant seemed identical with that collected by Griffith, and both were identified at Kew with the Javanese A. fovicaria. In 1888, Chauvet (Thése Bordeaux) examined the arrow poison of Indo-China, and came to the same conclusions concerning its poisonous properties as were arrived at by Regnault in 1878. In 1889, the Straits 350 URTICACEM. Government sent to Kew further specimens of Jpoh poison, which were again examined by Dr. Ringer with entirely negative results. Botanists were not, however, unprepared for this result. The Dutch botanist, Blume, in his fine work ‘ Rumphia,’ has given an elaborate account of the Javanese Upas and of the tree which yields it (pp. 46—59, tt. 22, 23), but he points out that Rumphius, our earliest authority on Malayan botany, distinguished two kinds of Upas trees, which he termed Arbor toxicaria femina and mas respectively. Rumphius’s femina was destitute of any poisonous qualities, and Blume has described it as a distinct species under the name of A. innovia (Rumphia, pp. 171—173, t. 54). He received specimens from the island of Timor, where Spanoghe* found that the sap was destitute of any poisonous effect on animals; he also gives Celebes as a locality for the innocuous plant. Other botanists have not, however, found themselves able to attach much weight to the distinctive characters pointed out by Blume, and there can be no doubt that what weighed principally in his mind was the remarkable difference in the properties of the two forms. Species are, however, made by botanists on structural (morpholo- gical) differences and not on physiological. In the same species of Cinchona it is now known that there are the widest differences in the amount and even nature of the alkaloids which can be extracted from the bark. An equally striking, and even better known instance of differences in properties, unaccompanied by any difference in external characters, 18 afforded by two well-known British umbelliferous plants, GEnanthe crocata and Cicuta virosa, which Sir R. Christison found to be innocuous when grown near Edinburgh. _ Brandis in his ‘Forest Flora’ has identified with A. innowia the A. saccidora of South-west India. According to Beddome, this is “the largest tree of the vergreen forestsof the Western Ghauts, and the hills betweem taem and the Coast.”” Sacks are made of the one I «wa bark. The method is thus described s account of the innocuous Upas of Timor is printed, yrinted, to- that of with Leschenauit on the virulent Bind 3 in Hooker’s Companion f fe Peal erat Vol. cm, 308—317 bal Se ea oe Re CRE PL) ‘ ier iz) ete URTICACEZ. 351 by Graham’':—‘‘A branch is cut corresponding to the length and diameter of the sack wanted, soaked a little, and then beaten with clubs till the fibre separates from the wood. This done, the sack formed of the bark is turned inside out, and pulled down, until the wood is sawed off, with the exception of a small piece left to form the bottom of the sack, which is carefully left un- touched.” Brandis remarks (/. c., p. 427) :—‘‘Another species of the same genus (Myah seik, Burm.) is found in the dense evergreen _ forests of the Thoungyeen Valley. In Tenasserim the juice is used by the Karens to poison arrows, but the poison does not seem equal in its effects to that of the famous Upas tree of the Indian Archipelago.” Mason refers the Pegu Upas to A. ovalifolia, a very large timber tree scattered in the forests from Mergui to Toungoo. The milky juice is intensely bitter, and when swallowed produces sore-throat. Arrows that have been smeared with it and hung exposed to the air, lose their power to pro- duce death, and there is said to be a difference in the virulence of the poison at different times of the year. Nothing more seems to be known of the tree which yields the Karen arrow poison, but it is very probably referable to A. tovicaria, and Gamble (Manual of Indian Timbers, p. 332) refers the Burmese name Myah seik to that species. (Archives de Physiologie, 2,1891 ; Kew Builetin, 50,1891.) In 1891, MM. E. Boinet and E. Hedon examined the arrow poison used by the Muongs of Tonkin. They found the quan- tity of the poison on each bamboo arrow to be about halfa gram of a brownish substance soluble in water. Three drops of a solution of 0°50 gram of the poison in 10 grams of water placed upon a frog’s heart arrested the pulsations in seven minutes, and a subcutaneous injection of one centigram of the poison proved fatal toa guinea pig. From twenty experiments, it was found that one centigram per kilo body-weight was rapidly fatal to the animals experimented upon. The authors arrive at the following conclusions :— 1st,—That the poison has no appreciable effect upon the 2 nervo-muscular or central nervous — 352 URTICAOEZ. 2nd.—The breathing is accelerated for a few minutes after the injection of the poison, but afterwards the number of respirations gradually decreases until death takes place. 3rd.—The final effect of the poison is to stop the heart in systole. In the poisoned frogs the ventricle was contracted, empty, hard and white. In the mammal the left ventricle was smaller and harder than usual, the right ventricle less contracted and full of dark blood. Before final stoppage the heart symptoms may be divided into several stages. In mammals, at a certain period after the injection of the poison, a sudden want of rythm was observed, the heart beating very irregularly. After- wards the pulsations became more and more feeble, with occasional stronger contractions, and finally periods of great depression alternating with periods of stronger pulsation were ~ observed, In all cases a few auricular pulsations occurred after stoppage of the ventricles. It was remarked also that pulsation could be re-induced by mechanical or electrical stimulation of the heart muscle, In the frog the first effect of the poison on the heart is a very marked doubling of the pulsations. Wheres in the normal condition the auricular contracti iately precedes the ventricular, and is shown on the pulse tracing by a slight hitch in the curve of the total pulsation; in the poisoned animal the two pulsations are separated by a marked interval, and finally the auricular curve becomes so marked as to equal or even exceed in size the gradually decreasing ventricular curve. _In the second stage the ventricle only contracts once to several auricular contractions, that is, it only contracts when it has become sufficiently distended with blood to excite con- tractions, In the last stage the strength of the auricular contractions gradually decreases, the ventricle remaining immovable, empty, and contracted. The authors conclude that the poison acts upon the intracardiac os and not upon the central URTICACER, — eae 353 The poison, we are informed, is prepared by the natives of ‘Tonquin from the leaves of A. foricaria, and experiments made by the authors with the leaves of that plant prove clearly that hey are the only active ingredient in the arrow poison. (Archives de Phys., 1891, p. 378.) : A still more recent investigation of the Ipoh poison by Mr. L. Wray, the Curator and State Geologist of Perak, has been from the tree by scoring the bark. The sap is heated on a ula till evaporated, leaving a dark gummy substance in which arrows are dipped ; 34 ounces of sap will do for poisoning 100 arrow points. The sap was bitter and biting in taste and decidedly acid to test paper ; when exposed to the air it darkens to a brown colour, and yields when dried 29 per cent. of Ipoh. If this substance is placed on a glass slide and examined. under a microscope it is seen to contain numerous crystals of antiarin. Some fruiting specimens of the Ipoh were sent to Kew in 1883, and were pronounced to be identical with the Javan specimens of A. towicaria. With reference to the two kinds of Upas distinguished by Blume as Arbor towicaria femina _ et mas, the latter word in Malay means “ gold” ; it is so called from the golden colour of the inner bark. In the innocuous _ variety, so say the Samangs, the inner bark is blackish coloured, and so they distinguish the poisonous from the non-poisonous trees. They have never mixed arsenic with the sap. One fluid ounce of Ipoh sap was found to yield 10°85 grains of antiarin or 2°482 per cent. The dried Ipoh poison, of which the sap contains 29 per cent., therefore has 8°56 per cent. of antiarin in it. 0-086 of a grain of the dried poison is ‘enough to kill an animal weighing 20 lbs., when introduced into the circulation. Fowls and pheasants are proof against the poison, but a cat struck with a poisoned dart died within 19 minutes. Bulletin for October and November 1891. Description,—The nuts are sub-globular, the size of a marble, of a light-brown colour, and have a slightly prominent umbilicus; they are enclosed in a sweet greenish-yellow pulp Ill —45 : lished in the Perak Gazette. He says :—The Samangs get the _ Mr. Wray’s Report has since been published in the Kew 354 URTICACEA, forming a small one-seeded fig with a mech purple bloom. The shell is thin and fragile, the kernel, loose inside the shell, is of the size of a large pea, brown, sub-globular, rugose, especially upon the flatter side; substance hard and very bitter. Chemical composition.—W hen the sap of the tree is exhausted with boiling alcohol, a mixture of vegetable albumin, gum and wax remains undissolved, while a solution is formed, which throws down, on cooling, wax, antiar-resin, and albumin. On removing the sediment and evaporating, more resin and wax are deposited, and the solution dries up at last to an extract, from a solution of which in boiling water Antiarin, C'“H®°O°+2H°, amounting to 3:5 per cent. of the dried sap, crystallises. The erystals are purified by washing and recrystallisation. Antiarin forms splendid silvery laminz resembling malate of lime. The flakes which separate from the alcohol after boiling it with the sap of A. fowicaria, consist of Antiar-resin, C°°H™0*, which may be obtained white by re-solution in boiling aleohol ; when dry it has a glassy fracture, but becomes pasty if warmed. It is not poisonous, whilst antiarin causes death if introduced into the circulation in minute portions. (Mulder in Gmelin’s Handbook, Vol. XV1., p. 217. The wax deposited'on cooling from an extract of the juice prepared with hot alcohol, and purified by boiling with water, is white and brittle, softening at 30°, and melting at 35°, sp- gr. 1016 at 20°. It is decomposed by nitric acid, blackened by sulphuric acid, and not affected by hydrochloric acid or potash- ley. It is soluble in alcohol and ether, especially on boiling. Average composition 77:29 per cent, Carbon, 11-71 H, and 11 O. _ (Ibid., Vol. XVIII, p- 158.) - The seeds of the Indian plant, collected in Savant Vadi, contain _® crystalline principle, very bitter and poisonous, ing, if not identical with, antiarin. It is soluble in water, —— and very slightly in ether. It gives a reddish- with sulphuric acid, and a yellowish or orange claus wilh nitric acid. On allowing the dried extract to stand, —_S ‘crystallize out, but if the alcoholic extract is dissolved in es ase which it is quite soluble (chewing URTICACEM. 355 absence of resinous matter), and the solution agitated with crude ether, crystals can be obtained from the decanted ethereal layer. The solution also reduced Fehling’s solution. About 2 per cent. of fat, 11°33 of water, and 3-46 of ash were sepa- _ rated from the air-dried seeds. The juice of Artocarpus integrifolia, Linn., the well- own Jack tree, in Sanskrit Panasa, heated over the fire, is a pular cement for joining broken China and _ stoneware. e deposit from the milky juice is insoluble in water, partly uble in alcohol, and entirely so in benzol. It is a variety — caoutchouc, and in the natural state can be used as a rdlime, or as a cement for broken articles; after being washed in boiling water it becomes harder, and may be used for all the ordinary purposes of India-rubber. The yellow dye which is obtained from the wood is of a resinous nature, and may be extracted by boiling water or alcohol. The juice of A. Lakoocha, Rozb., or one or two of the seeds, is a popular purge in Bengal; the tree is the Dahu of Sanskrit writers. ~Rheede states that the dry leaves and juice of A. hirsuta, _Lamk., together with zedoary and camphor, are applied to buboes and swelled testicles, The dried juice breaks with a resinous fracture, is only partly soluble in alcohol, wholly soluble in benzol and petroleum ether. The tree yields the Anjelly wood — _ of South India, and is called Ayani in Malabar, where it is very t. MYRICACEA:. MYRICA NAGI, Thund. Fig.—Bot. Mag., t. 5727; Wight Ic., t. 764, 768. Hab.—Subtropical Himalaya. The bark. Vernacular.—Kaiphal, Kétphal (Hind., Guz., Beng.), Kaya phala. (Mar.), Marudam-pattai (Zam.), Baideryama (Zed. ore en toli (Mal.), Kirishivani (Caz.). 356 : URTICACEZ. History, Uses, &c.—The bark of this tree is its most valuable product, and is largely exported to the plains. It is ealled in Sanskrit Katphala, and bears among other synonyms those of Kumuda, Kumbhi-péki, Sriparnika, Somavalka, and Mahakumbhi. According to the Nighantas, it is useful in — diseases caused by deranged phlegm, such as fever, asthma, gonorrhea, piles, cough, and other affections of the throat. It is an ingredient in numerous formule for these diseases, such as the Katphaladi churna, for which Sarangadhara gives the following prescription :—Take of the bark of M. Nagi, tubers of Cyperus rotundus (Mustaka), root of Picrorhiza Kurrooa (Katuki,), Curcuma Zedoaria (Sati), galls of Pistacia integerrima (Karkata-sringi), and root of Sausswrea Lappa (Kushta), equal parts; powder and mix. This powder is given in doses of about a drachm with the addition of ginger juice and honey in affections of the throat, cough and asthma, The powdered bark is used as a snuff in catarrh, and angers with ginger as an external stimulant application in cholera, Under the names of Daér-shishaén, Kandal, ae Ud-el-bark, Mahometan writers state that the bark is resolvent, astringent, carminative, and tonic; that it cures catarrh and headaches; with cinnamon they piecaeti it for chronic cough, fever, piles, &c. Compounded with vinegar it strengthens the gums and cures toothache ; an oil prepared from it is dropped into the ears in earache. A decoction is a valuable remedy in asthma, diarrhoea and diuresis; powdered or in the form of lotion the bark is applied to putrid sores; pessaries made of it promote uterine action. The usual dose for internal administration is about 6' grains. Duhn-el-kandi/,.an oil prepared from the flowers, is said to have much the same properties as the bark. We have ‘never met with it, nor does it appear to be known in commeree. Description.—Bark half an inch thick, externally _seabrous, pitted from the separation of pieces of suber, of 4 ue. mottled rusty-brown and dirty white colour, suber warty; (aah of ; and inner surface of a deep dull red colour ; ater it —— a a red a ese : *)Seipe eanae CASUARINER, — 3h Microscopie structure.— Within the suberous layer is a remarkable stratum of stony cells; the parenchyma throughout is loaded with red colouring matter, and permeated by large laticiferous vessels, from which a gummy latex exudes when the bark is soaked in water. Chemical composition.—The bark of M. Nagi contains 14 per. cent. of tannin, which gives a purplish colour with ferric salts, but the tincture and decoction give a greenish colour owing to the presence of colouring matter in the bark. The ash of the air-dried bark amounts to 7°17 per cent. When the bark is exhausted by water and the water eva- porated, a brittle shining extract is obtained of a reddish-brown colour, which contains 60 per cent. of tannin with some saccharine matter and salts. Commerce.—The bazaars are supplied from Northern India; about 50 tons of the bark are collected annually in the Kumaon forests. It is always obtainable in native drug shops. Value about Rs, 2 per maund of 41 pounds. CASUARINE. CASUARINA EQUISETIFOLIA, Forst. Fig.—Beddome, Forester’s Man., t. 226. Tinian Pine (Eng.), Filao de l’ Inde ( F*.). Hab.—East side of the Bay of Bengal. Cultivated else- where. The bark, leaves, and seeds. Vernacular.—Sinyu (Burm.), Chouk (Tam.), Sarva (Tel. é K4srike (Mysore), Aru (Ma/.), Vildyati-saru (Mar.), History, Uses, &c.—This tree is distributed ie Chittagong, Burma, the Malay and Pacific Islands, and : In Australia, and is much cultivated on the coasts of India. I 358 CASUARINE. Australia it is called the swamp oak. Dr. Bennett (Gather- ings of a Naturalist in Australia) remarks: —‘‘ Their sombre appearance causes them to be planted in cemeteries, where their branches give out a mournful sighing sound, as the breeze passes over them, waving at the same time their gloomy hearse- like plumes.” The wood from its red colour is called in the colonies Beef-wood, and is much used for fuel, and as a timber on account of its hardness. The bark is astringent, and the ashes of the trée yield a quantity of alkali. The bark is used by the Madras fishermen for dyeing their nets. Rumphius notices the use of a decoction of the bark for a bath in Beri-beri, and of a decoction of the leaves in colic. The pounded seeds, he says, are used as a plaster in headache. : According to Corre and Lejanne (Mat. Med. et Tor. Colon.), the bark contains one-fifth of its weight of tannin and one- twelfth of Casuarine, resin, and colouring matter. A decoction, extract, tincture and syrup are used by the French in Tahiti, Cochin-China, and the Antilles as an astringent. We have observed that the tree yields an inferior sort of gum, not likely to be of much value on account of its deep colour and insolubi- lity in water. Description.—Bark never very thick, brittle, breaking with a coarse fibrous fracture, substance very hard, fibrous, and of a pink colour; internal surface striated; external surface covered with a scabrous grey suber, readily separating in flakes, and displaying a thin brown suberous layer closely adhering to the liber; taste strongly astringent; odour not Chemical composition.—The bark yielded 18:3 per cent. of tannic acid, giving a blue-black precipitate with ferric salts, and a bulky precipitate with gelatine. The alcoholic extract contained no alkaloidal principle, but a very small quantity of a erystalline neutral principle was shaken out of the watery — of the extract by ether; it was not coloured by strong CUPULIFERZ, 359 CUPULIFER&. | BETULA UTILIS, Don. Fig.—Regel Monogr. 58, ¢. 6, f. 13-19; ¢. 18, f. 7-14; Jacg. Voy. Bot., ¢, 158. Himalayan Birch (£ng.), Bouleau 4 papier (Fr.). Hab.—Temperate Himalaya, Afghanistan, BETULA ALNOIDES, Ham. Fig.—Brand. For. Fl., t. 56; Regel Monogr. 61, ¢. 6, J. 32-34 ; ¢. 13, f. 29. - Hab.—Temperate and subtropical Himalaya. The bark. Vernacular.—Bhujpatar (Ind, Bazaars). History, Uses, &c.—These trees require a brief notice, as the bark, in Sanskrit Bhurjapatra, is much used all over the country for writing medicinal charms on, and is to be found in every druggist’s shop. This bark is well-known as the material upon which the ancient Sanskrit manuscripts of Northern India are written. Dr. Biihler, in his account of a tour in Cashmere in search of Sanskrit manuscripts, says:—‘‘ The Bhurja MSS. are written on specially prepared thin sheets of the inner bark of the Himalayan birch, and invariably in Sarada characters. The lines run always parallel to the narrow side of the leaf, and the MSS. present, therefore, the appearance of European books, not of Indian MSS., which owe their form to an imitation of the Talapatras. The Himalayas seems to contain an inexhaustible supply of birch-bark, which in Cashmere and other hill coun- tries is used both instead of paper by the shop-keepers in the bazaars, and for lining the roofs of houses in order to make them : water-tight. It is also exported to India, where in many places : it is likewise used for wrapping up parcels, and plays an import- ant part in the manufacture of the flexible pipe-stems used by huka-smokers. To give an idea of the quantities which are brought into Srinagar, I may mention that on one single day aS ee. Se et mw eae, eet eee ne xt, Rae Dek oe we GPT ees hah Pe ee Bet Seton BOIS ee meine a Ponies 5s © i mae che tat emery vats 5) Se Sere ees aay 360 CUPULI FER. I counted fourteen large barges with birch-bark on the river, and that I have never moved about without seeing some boats laden with it. None of the boats carried, I should say, less than three or four tons’ weight. “ The use of birch-bark for literary purposes is attested by the earliest classical Sanskrit writers. Kalidisa mentions it in_ his dramas and epics; Susruta, Varahamihira ( circa 500-550 A.D.) know it likewise. Akbar introduced the manufacture of paper, and thus created an industry for which Cashmere is now famous in India. From that time the use of birch-bark for the purpose of writing was discontinued, and the method of prepar- ing it has been lost. The preparation of the ink, which was used for Bhirja MSS., is known. It was made by converting almonds into charcoal and boiling the coal thus obtained with gomttra (urina bovis); this ink is not affected by damp or water.” (Journal, Bombay Branch Royal Asiatic Society» Vol. XII., No. XXXIV. A.) QUERCUS INFECTORIA, Okivier. ; ~Fig.—Benii. and Trim., t. 249; Olivier, Voy. dans ? Emp. - Oth. ii., p. 64, Atlas, tt. 14, 15; Steph. & Ohurch, t. 152. Dyers’ oak ( Hng.), Chéne a la galle (/’.). - Hab.—Asia Minor, Syria, Turkey. The galls. Vernacular.—Majuphal, M&phal (Hind., Beng.), Maiphala, Maja (Mar.), Mashik-kéy (Tam.), Mashi-kéya (Te/.), Machi- kéyi (Can.), Mayaphal (Guz.). _ History, Uses, &c.—The Sanskrit name for galls is Méyin or Mayika, and signifies ‘‘ magic,” the gall-nut being used in India in magic rites. Galls were well known to the Greeks and Romans, who used them medicinally on account of their astringent properties.” India has probably been supplied with them from an early date, vié the Persian Gulf, the greater portion being still shipped at Basra on board Arab vessels, hence the names Basra * Compare with Dios., i. 127. mepi xykiBov; and Pliny, 16, 9, and 24, 5. CUPULIFERR, | 361 and Maka galls. The medicinal uses to which galls are put in India hans differ from those with which we are familiar. The Hindus divide them into two kinds, black and white, and generally prescribe both kinds together in the same presecrip- tion. Mahometan writers direct the dark-coloured unper- _ forated galls to be selected as the best. The Arabs call them was (q/s), and say that the tree, which i is not of the land of the Arabs, bears one year galls and another Ballit (acorns). In Persia they are known as Mazi or Mé4zin ; Bae I se yead” pope 65 Aes! orf pr oh galls are generally used in preference to the raw material. ‘The action of tannin is chiefly local, and is due to its power of coagulating albumen; it is therefore a useful application when the skin has been deprived of its epidermis by diseases such as intertrigo, impetigo and eczema, as it forms with the exudations a protective coating, and at the same time contracts _ the cells of the skin. _ When applied to a mucous membrane, it causes dryness, coag- ulation of mucus, and destroys to a great extent the sensibility of the membrane; on this account it is employed in stomatitis, sore-throat, and cough due to irritation at the back of the pharynx, and also as an injection in chronic discharges from the genito-urinary passages. When taken into the stomach in large doses it causes irri- tation, and possibly vomiting, but in smaller doses it is often useful in hematemesis and intestinal hemorrhage by coagulating _ the blood and thus acting as a styptic. In poisoning by the alkaloids it acts as a chemical antidote by forming tannates which are but sparingly soluble in the juices of the alimentary canal; it is also used as an antidote in poisoning by tartar used as an antidote its administration should be followed by a purgative, asthe tannates of the alkaloids will be partially _ redissolved, if allowed to remain in the intestines. ILL—46 the author of the Burhdn says they are —_ by tanners, — emetic, with which it forms an insoluble tannate. When — 4 In modern medicine tannic and gallic sate obtained from _-menters. 362 OUPULIFERZ. Dr. R. Stockman has conducted a series of careful experi- ments with gallic and tannic acids, with the object of determin- ‘ing the influences which the vegetable astringents exert upon the blood-vessels and animal tissues after absorption. He finds that tannic acid on its entry into the stomach forms alkaline tannates and tannates of albumin. A part of it, and sometimes the whole, is converted into gallic acid in the stomach and intestines, and it is difficult to find a trace of tannic acid in the blood, although it can be detected in the urine. Dr. Stockman comes to the conclusion that tannic acid enters the circulation in combination with alkalies and albumin, and is excreted with such rapidity that only a trace of its presence can be detected in the blood, but that its presence in the genito-urinary tracts and in greater quantity in the intestines can be readily shown. It does not appear to be excreted by the mucous lining of the air passages. It was found that the urine of dogs, rabbits, and human beings, after the administration of tannic acid, contained gallic acid and only a small quantity of tannic acid, but when tannate of soda was administered the urine contained a large proportion of tannic acid and but little gallic acid. These results may be explained in the following manner :—When free tannic acid is brought in contact with the contents of the stomach, it is chiefly converted into tannate of albumin, only @ small quantity of alkaline tannate being formed. The tannate of albumin being very insoluble is retained for a long time in the intestines, until it is in a condition to be converted into gallic acid, in which form it is at length absorbed; on the other hand, the alkaline tannate is at once absorbed and passes off in the urine. Under these circumstances, the administration of tannate of soda naturally gives rise to the presence of a large Proportion of tannic acid and a small proportion of gallic acid in the urine, Dr. Stockman did not find pyrogallic acid in the urine, but this experience is in opposition to that of other experi- i ee cca acid was “orate that acid only was found. CUPULIFERA. 363 _ According to Dr. Stockman, tannic acid exerts no action upon the urinary excretion, and gallic acid does not cause contraction of the blood-vessels, but on the contrary dilates them even after contraction has been induced by the action of an alkaline iquid. The neutral gallate of soda, in which form gallic acid culates in the blood, was found to have no action upon the f Fikentscher has stated that tannic acid adminis- red hypodermically to frogs stimulates the vaso-motar centres and iucreases the blood pressure, but Dr. Stockman found that gallate and tannate of soda administered in this way to rabbits did not affect the pressure. Pyrogallic acid yielded similar results. As regards the therapeutic value of gallic ame asa local appli- that it has no special astringent ahah but that it diminishes the alkalinity of the blood and increases its tendency. to doubtful whether it exerts any therapeutic action, but Ribbert considers that it lessens the exudation of albumin in albumi- nuria. Tannic acid is sometimes injected into the rectum to destroy thread worms, which it does by coagulating the albumin ‘in their delicate tissues. Description.— Two kinds of gall are found upon Oak trees, hard and soft; the former are the galls of commerce, and - are produced by a Cynips which punctures the buds of the tree and deposits its egg in the puncture; the latter result from the puncture of an aphis. Gall-nuts are globular or pyriform bodies, studded with numerous tuberosities; those which still contain the inaged are 364 SALICINEZ. of a blackish or bluish-green colour and heavy; those from which the insect has eseaped are of much lighter colour, gene- rally yellowish-white, on one side a round hole may be perceiv- ed ; they are also lighter in weight and less astringent. When a gall is cut in two a round cavity is seen in its centre, which may or may not be occupied by the insect; in the latter case a passage leads from the cavity to the exterior. Microscopie structure. —The contents of the central cavity, if present, are seen to consist of a starchy parenchyme destined to supply food to the larva. The walls of the cavity are formed of stone-cells. The bulk of the gall consists of cells arranged in a radiating manner, many of them containing colouring matter and tannin. Towards the exterior of the gall the cells contain dark-coloured chlorophyl; on the very surface the cells are small and thick-walled and form a kind of rind. Chemical composition.—The principal constituent of galls is tannin or tannic acid. The tannin of different plants possesses distinctive characters ; that obtained from galls is known as gallo-tannic acid. It isi identical with the tannin of Rhus cort- aria, Linn. (Sumach). Galls afford from 60 to 70 per cent. of tannin, and about 2 per cent. each of gallic and ellagic acids. Commerce.—Galls are imported from Basra and the Persian Gulf ports. Value: White, Rs. 10 per maund of 374 lbs.; Blue, Rs. 17. Imports about 1,400 cwts. yearly. SALICINE, SALIX CAPREA, Linn. Fig.—Eng. Bot,, 1488; Reichb. Fl. Germ,, t. 577. Great ates Sallow, Goats’ Sallow (Hng.), Marceau, Marsault r. _ Hab.—Persia, Europe. Cultivated in N.-W. India. The bark, Hates Sa and, porate. ‘SALICINES. 365 History, Uses, &c,—The willow izéa was well-known to the ancient Greeks, and the Greek name is considered to be cognate to the Sanskrit Vitika, the old German Wida, and the > old English With or Withy. Herodotus (i.,194) mentions it, and Theophrastus (H. P. ii., 13) mentions two kinds, Acv«y and péAawa, Dioscorides 4,121) notices its astringent pro- perties, and the various medicinal uses to which the bark, leaves, seed and juice were put. Pliny (17, 20) describes the cultivation of the willow, and (24, 9) its medicinal properties. The ancients considered it to be very cooling, ‘‘ Porro impediunt et remittunt coitum folia salicis trita et epota”; it was also _ thought to occasion sterility in women. The concrete juice of the plant mentioned by Greek and Latin writers is considered by Fée to have been a kind of manna. Ibn Sina, under the name of Khilif, follows Dioscorides closely in his description of the medicinal uses of the willow, but he mentions the use of the flowers of 8. Caprea separately under the name of Behramaj, a corruption of the Persian Behrameh. The Mahometan physicians all mention the juice or gum ( &<) of the plant, and Haji Zein states that it exudes from the leaves. ‘It is probably the substance’ described by M. Raby (Union Pharm., May, 1889), under the name of Bidenguébine or ‘‘willow honey,’ said to be derived from the leaves and young branches of a willow, and to have a feebly saccharine taste. In Persia S. Caprea is known as Bid-i-Balkhi, and its flowers as Bidmishk; willow bark is still a popular febrifuge in that country. Aitchison mentions the following species of Salix as occurring wild or cultivated in Persia:—S. pycnostachya, Anders., S. acmophylla, Boiss., S. babylonica, Linn., S. Daviesii, Boiss., S. alba, Linn., S. songarica, Anders., and S. Caprea, Linn, In China and Persia the tree is considered to be symbolic of immortality. S. babylonica is planted in burial grounds in the latter country, and has been introduced into India by the Moghals for this purpose; among the Romans it was sacred to 366 SALICINE. Juno Fluonia. For an account of the funereal use of the willow in China, the reader is referred to Schlegel’s Uran- ographie Chinoise, or De Gubernatis’ Myth. des Plantes, article Saule. The Persian settlers in India have introduced the flowers (bidmishk) and the distilled water (ma-el-khilaf) of S. Caprea, both of which are used by the upper classes of Mahometans and Parsees, who consider them to be cephalic and cardiacal, and use themas domestic remedies in almost every kag of slight ailment. Raughan-i-bid, an oil prepared by boiling two parts of the distilled water with one of sesamum oil until the water has all evaporated, is a favorite remedy for cough. Fora long series of years the willow fell into disuse in Europe, but was again brought into notice in 1763 by the Rev. Mr. Stone, who published a paper on the efficacy of the bark of - S. alba as a remedy for agues. The broad-leaved willow bark (S. Caprea) was subsequently introduced into practice by Mr. James, whose observations on its efficacy were afterwards confirmed by Mr. White and Mr, G. Wilkinson (Pereira, Mat. Med., ii., Pt. 1, p. 837). Willow bark was formerly official in the London, Edinburgh, and Dublin Pharmacopeeias, and was consi- dered no bad substitute for cinchona in agues. S. Caprea is one of those willows which yield salicin and tannin, and is remarkable for its large yellow fragrant catkins. Salicin, which was discovered in 1825, and first obtained in a pure state in 1830, was at first much vaunted as an antiphlo- gistic by Riess and others in those cases in which salicylic acid is now employed; it was also used as an antiperiodic in ague, and is said to have been found efficient in preventing the _ development of acute coryza and influenza, and in mitigating the symptoms of hay fever. It was usually administered in _ 10-grain doses frequently repeated. More extended experience, = : petit led to the conclusion that it has little or no influence a the temperature, and the ually fell into disre : until PN airy the a Aanmaeg y pute + ¢ properties of une ‘ : SALICINE:. 367 acid, when it was again experimented with by Ringer and — _ Bury, who showed that it had no influence upon the tempera- ture of healthy children. They observed that under full medicinal doses a dusky flush suffuses the face on slight excitement, while the expression becomes dull and heavy. Less constant symptoms are deafness, noises in the ears, frontal headache, trembling of the hands and quickened breathing, Very large doses occasion severe headache, marked muscular ~ weakness, tremor and irritability, with a rapid and feeble pulse. Description.—Catkins 1—2 inches long, thick, eylin- drical, bright yellow, fragrant; bracts oblong, small; scales obovate, blackish, hairy; nectary ovate, papillary; stamens longer than the scales, with oblong yellow anthers ; germ ovate- lanceolate, silky, on a hairy stalk; style hardly any; stigma oblong, thick, undivided. Bark warpliak:. brown externally, minutely downy when young, internally white; tough and fibrous. Chemical composition.— Willow bark has been shown to con- tain salicin, wax, fat, gum, and a tannin which gives with ferric salts a blue-black precipitate, the liquid becoming pur- plish-red on the addition of soda. Johanson (1875) has also shown the presence of a kind of sugar having a slightly sweet — taste and reducing alkaline copper solution with difficulty, and of the glucoside benzohelicin, C?°H*°O®, Salicin, a glucoside, erystallizes in colourless plates or flat rhombic prisms, but it - usually occurs in commerce in white glossy scales or needles, It remains unaltered in the air, is neutral to test-paper, in- odorous, and hasa persistently bittertaste. It is soluble in about ~ 30 parts of water at 11-5° C., and is somewhat less soluble in alcohol. It dissolves in 0°7 part of boiling water and in 2 parts of boiling alcohol. (United States Pharm) Cold sul- phuric acid dissolves salicin with a bright red colour; after the absorption of water from the air (but not after the addition of water or after being neutralized by an alkali), the solution deposits a red powder (rutilin), which after washing i is yellowiale = red, after drying blackish-brown, insoluble in water, 368 SALICINEA, and glacial acetic acid, and is coloured violet-red by alkalies, (Braconnot.) On warming salicin with somewhat diluted sulphuric acid and potassium bichromate, salicylous acid or salicyl-aldehyd, C’H°O’, is given off, recognizable by its peculiar fragrance, resembling that of meadow-sweet (Spirea ulmaria). Salicin when digested with emulsin or saliva, or heated to 80°C. with dilute sulphuric acid, assimilates 1 molecule of water, and is split into glucose and salicylic alcohol or saligenin, C’H°O’, which crystallizes in pearly tables, is easily soluble in hot water, alcohol, and ether, melts at 82°C., and sublimes at 100°C. Saligenin is characterized by yielding in solution a deep-blue colour with ferric chloride, and when boiled with dilute acids by being converted into a resinous body, saliretin, C'*H'*0%, while oxidizing agents convert it into salicylous and salicylic — acids. Cold nitric acid, sp. gr. 1:16, oxidizes salicin, with the production of helicin, C'%H?*O’, which crystallizes in white needles, and is by ferments and dilute acids resolved into sugar and salicylic aldehyd. If nitric acid of sp. gr. 1-09 is employed, salicin yields helicoidin, C*°H**O'*, which may be regarded as a compound of salicin and helicin. (National Dispensatory.) For a full account of these interesting reactions, the reader is referred to Watts’ Dict. of Chemistry, Vol. V., p. 147. Bidangubin or ‘‘ willow honey ” has been examined by Raby (Union Pharm , May, 1889, p- 201). It affords about 12 per cent. of sugar, estimated as glucose, and a considerable quantity of a sugar crystallizing in opaque hard crystals like those of sugar of milk. It melts at 150° to a transparent liquid, and — dissolves in 5:5 parts of water at 15°C. The formula is given - as C"H”O", This sugar evidently possesses considerable affinity to melezitose, from which it differs, according to M. Raby, in not being efflorescent, and in the greater rotatory power of the glucose derived from it by inversion over that obtained from melezitose. The inversion by means of dilute hydrochloric acid also takes place more rapidly. He therefore gos GNETACEA. 369 ~GNETACE. EPHEDRA VULGARIS, Rich. | ae Ic. Fl. Germ., t. 539 ; Bertolon. Miscell. xxiii., —t.3 . Hab .—Temperate and Alpine Himalaya, oe W. and ntral Asia, J apan. EPHEDRA PACHYCLADA, Boiss. Hab.— Western Himalaya, Afghanistan, E. Persia, | Vernacular.—E. vulgaris—Amsania, Butshur, Cheva (Puny.), _Khanda, Khama (Kunawar), Phok (Swutlej), Ma-oh (Japan). E. pachyclada—Hum, Huma (Pers., Bomb.). History, Uses, &c.—These two species are hardly different; E. pachyclada is rather more robust than Z. vulgaris and more scabrid. Of the former, Sir J. D. Hooker remarks :— “T can find no good characters in the spikes and flowers, except the more or less margined bracts.” A specimen of the Persian _ plant kindly furnished to one of us by Mr. K. R. Cama of Bom- bay, was identified at Kew as E. vulgaris. Dried branches of the Huma are still brought from Persia to India for use in Parsi ceremonial,and it is considered tol 1 properties. The plant was used by the ancient Arians, and is probably the same as the Soma of the Vedas. Aitchison (Proc. Linn. Soc., x., 77) notices the medicinal use of E. vulgaris in Lahoul, and he and Griffith state that the ashes of #. pachyciada are used as a snuff and dye in Afghanistan. Dr. N. Nagai of Tokio, Japan (Berl. Klin. Wochenschr., 1887, 706), first drew attention to the fact that _E. vulgaris contains an alkaloid (ephedrine) which possesses the property of dilating the pupil of the eye, and which may be used in the place of atropine. T. V. Biektine (Bolnitch. Gaz. Bot-— kina, 1891, No. 19, pp. 473—476) has brought to notice the use of a decoction of the stems and roots of EF. vulgaris as a popular remedy for rheumatism and syphilis in Russia, and of the juice of the berries in affections of the respiratory passages, After JI1.—47 370 GNETACEAE. administering the decoction himself in a number of cases” of rheumatism, acute and chronic, he comes to the conclusion that the plant is especially valuable in acute muscular and articular forms of the disease: the pain is relieved, the pulse becomesless rapid and softer, and the respiration easier. Within 5 or 6 days the temperature becomes normal, the swelling of the joints disappears, and after about 12 days’ treatment the patient is cured. In several cases marked diuresis was observed before or about the time that the temperature began to decrease ; the drug was also observed to improve the digestion and promote the action of the bowels. In chronic cases the action of Ephe- dra was less marked, and in two cases of rheumatic sciatica and osteo-myelitis hardly any effect was produced, but it is only — fair to remark that antipyrine, salicylate of soda, antifebrine, salol, &c., also failed to afford relief in these two cases. Th decoction used by Dr. Biektine was made with 3°85 grams of the drug to 180 grams of water. Kobert has shown that 0°20 gram of ephedrine injected into the veins of dogs and cats” produces violent excitement, general convulsions, exopthalmia and mydriasis. (Nouveaux Remédes, Aug. 8th, 1891.) Description.—£. vulgaris is a low-growing, rigid, tufted shrub, with usually a gnarled stem and erect green branches which are striate and nearly smooth. Bracts connate to the middle, not margined, eciliate, rarely produced into minute linear leaves. Spikelets } to $ inch, subsessile, often whorled ; fruiting with often fleshy, red, succulent bracts, 1 to 2 seeded. seeds bi-convex or plano-convex, __E. pachyelada has the same characters, but is usually more _ seabrid. Sir J. D. Hooker remarks:—‘‘I have many specimens from N.-W. India that I do not know whether to refer to . vulgaris or pachyclada.” The twigs of these plants have a terebinthinate and astringent taste, and sections when magni- fied show the tissues to be loaded with an inspissated red juice. Chemical composition —Dr. N. Nagai (Tokio Chem. Society, _ through Chem. Zeit., 1890, p. 441) obtained the alkaloid Ephedra vulgaris (Ma-oh). Its ag * CONIFERA. S71 > composition is C!°H'*NO ; by oxidation the alkaloid is split tite benzoic acid, monomethylamine and oxalicacid. Isoephedrine, melting point 114°C., is obtained by heating ephedrine, melting point 30°C., with hediseb lone acid in a closed tube to 180°C, The constitution of ephedrine is C°H°CH? CH (NHCH?) : CH°OH, and that of isoephedrine is C°H°CH°C (OH) (NH CH*) CH*. _ The hydrochlorate of ephedrine forms acicular crystals which are freely soluble in water. Mr. J.G. Prebble (1889) found the twigs of L. vulgaris to contain 3 per cent. of a tannin, riving a whitish precipitate with gelatine and acetate of lead, ' anda greenish precipitate with acetate of iron. CONIFER. JUNIPERUS COMMUOUNIS, Jann. Fig.—Richard. Conif. 33, t. 5; Reichb. Ic, Fl. Germ., #. 535. Juniper (Hng.), Genévrier (Fr.). Hab.—Western Himalaya, Persia. The fruit. Vernacular.—Hab-el-a’ra’r (Ind. Bazars). History, Uses, &c.—A’ra’r (465+) is a Persian word ; the author of the Burhdn notices a popular belief that the Juniper is the enemy of the Date tree, and that the two will not grow together in the same place. Abu Hanifeh states on the authority of an Arab of the people ° "of the Sarah, who are -possessors of the a’ra’r, that it is the same as the Abhal (the ‘latter name is applied in modern Arabic to the Juniper and ‘Savine). He adds that he knew it in his own' country, and afterwards saw it in the province of Kazween, cut for firewood from the mountains, in the neighbourhood of Ed-Deylem, and that the fruit is eaten when ripe. J. communis is a native of Greece, and must therefore have been known to the ancient Greeks, but there is much difficulty in identifying the two _species of aes mentioned by Dioscorides. The fruit on 372 CONIFERA. species of Juniper was, however, used by Hippocrates in certain disorders of the womb, and Dioscorides mentions its diuretic properties, its use in cough and pectoral affections, and also its digestive properties. The ashes of the bark were also applied locally in certain skin affections. Ibn Sina closely follows Dioscorides and gives no additional information concerning the plant. The several kinds of Juni- per growing on the Himalayas do not appear to be used- medi- cinally by the Hindus, and the berries sold in the bazaars by Mahometan druggists are all imported from the west via Bombay. In modern medicine Juniper is only used as a diuretic. Description.—Juniper-berries are nearly globular, about 3 inch in diameter, dark-purplish, and covered with a bluish- gray bloom; the short stalk at the base contains one or two whorls of the small scales, and the apex is marked by three radiating furrows, which are surrounded by ridges enclosing 4 triangular space. The three, or by abortion one or two, bony seeds are ovate in shape, triangular above, have six to ten large oil-sacs on their surface, and are imbedded in a brownish pulp which likewise contains oil-cells. The berries have an aromatic somewhat balsamic odour, and a sweet, terebinthinate, bitterish, and slightly acrid taste. ; Chemical composition.—Juniper-berries were analysed by Trommsdorff (1822), Nicolet (1831), Steer (1856), and Donath (1873). They contain from } to 24 per cent. of volatile oil, about .30 per cent. of sugar, resins amounting to 10 per cent., _ 4 of protein compounds, fat, wax, formic and acetic acids, malates, and juniperin, which is light-yellow, slightly soluble in water, freely so in alcohol and ether, and with a golden-yellow colour in ammonia. Ritthausen (1877) obtained from juniper- berries, containing 10-77 per cent. of water, only 14°36 per cent. of sugar, 3°77 of ash, and 31:60 of cellulose. o Oil of juniper-berries is colourless or pale greenish-yellow, limpid, but on exposure rapidly thickens and turns yellow, and ; ultimately reddish-brown, at the same time acquiring an acid CONIFERS. 373 reaction; the fresh-distilled oil from old juniper-berries is thick- _ ish and light-yellow. Its specific gravity is about *870, but x varies between °85 and ‘90; it begins to boil at 155° C., or, if _ obtained from ripe berries, at 205° C. (Blanchet), has the peculiar odour of the berries and a warm, aromatic, somewhat sweetish and terebinthinate taste, shows a neutral reaction to test-paper, turns polarized light slightly to the left, and is slightly soluble in alcohol, forming with 10 or 12 parts of 80 per cent. alcohol or tion ; but it yields clear mixtures with carbon disulphide in all proportions. Iodine dissolves slowly in the limpid oil, but acts more energetically upon the thickened oil, sometimes producing fulmination ; sulphuric acid colours it brown and red. Old oil _ of juniper contains formic acid, from which it may be freed by sodium carbonate and rectification. The oil is a mixture of hydrocarbons of the general formula _ ©'° H', which differ in their boiling-point, a portion boiling at 282°C. It yields with hydrochloric acid gas a liquid compound. (Stillé and Maisch.) Fig.— Wall. Tent. Fl. Nep., t.57; Griff. Ie. Pl. Asiat., 376 ; Bentil. and Trim., t. 253. Yew (Eng.), If (27.)- Hab.—Temperate Himalaya. The leaves, ; TAXUS BACCATA, Linn. F | , Vernacular.—Télispatar (Ind. Bazars). History, Uses, &c.—Under the name of Talisa-pattra or Talipattra, Sanskrit medical writers describe a drug which has carminative, expectorant, stomachic, tonic and astringent properties, and is useful in phthisis, asthma, bronchitis, and vesical catarrh ; the powdered leaves are given with the juice of Adhatoaa Vasica (vasaka) and honey in cough, asthma, and with Talispattra, black pepper, long pepper, ginger, hemoptysis. A confection called Talisadya churna is ee: on O74 CONIFER. manna, cardamoms, cinnamon, and sugar, and is used in the abovementioned diseases. The author of the Burhan, the oldest Persian Dictionary, which contains a large collection of Pahlavi words, mentions the same drug under the name of Télisfar, and states that this name was applied by the Greeks to the leaf of the Indian Olive, or, according to some, to its root- bark. Ibn Sina speaks of it as an Indian bark, and describes its properties in the same manner as the Sanskrit writers; he states that Galen considers it to be possessed of hot and cold properties in equal proportion, but that others say it is hot and dry. Yahia bin Isa, the author of the Minhaj, considers Talisfar to be the leaf of the Indian Olive; Ibn Baitar thinks that it is Mace. Haji Zein-el-attdér identifies it with the vaxep of the Greeks, and says it is the root-bark of the Indian Olive, a bark thicker than China cinnamon and harder and of a darker colour, very astringent and slightly aromatic. ‘he author of the Makhzan-el-Adwiya mentions the drug in two places, and identifies it incorrectly with the Zurigh of the Arabs; he also appears to confound it with Hydrocotyle asiatica, Speaking of Zarnab, he says, “it is also called Rijl-el-jardd (locust’s foot). In Hindfit is brahmi, barambhiand sapni, and one kind of it is called Manduparni and barahmi, and the plant is called Té/is, and the leaves, which are the same as Zarnab, are called Télispatr. It is a plant with leaves broader than those of Sdtar-i-bari, of a yellowish colour, and scented like a citron; the flower is yellow, and the plant is less than a cubit in height, with a quadrangular hollow stem; it has a pungent taste, and retains its properties four years. It grows in the hills of Fars, and is called Sarv-i- - Turkisténi ; it is also found in Hindustan and Bengal. * * * * It is hot and dry in the second degree, and has stimulant, astringent, stomachic, pectoral and digestive properties similar to cinnamon; me fresh j juice is intoxicating; mixed with oil of iolet introduced into the ear it cures cold headache. . ‘Substitutes, double the quantity of cinnamon, cubebs, cassia, or cardamoms.****” Again, speaking of Télisfar,* an article Fe gD REN Seeman eet thane esis same oe beer name Royle obtained the leaves of Rhododendron lepidotum, which are highly aromatic. at: vee Med., p. 91.) CONIFERZ. «ome il scribed as one concerning the identity of which there is much difference of opinion, the author of the Makhzan says, “perhaps t is the same as Zarnab, which is called Télis in Hindi, and ich is the narrow leaf of a tree of a dusty colour, externally and nternally yellow.” If we turn to the older Arabian writers, we fin that we have no reason to identify Zarnab with Télisapattra ; say that it is a certain perfume or certain sweet- -smelling Kamis), or a species of sweet-smelling plant (Sihah) ; it ts of slender round twigs, between the thickness of large dles and of writing reeds, black inclining to yellowness, not haying much taste or odour, what odour it has, being of a ragrant kind like citron. (Jbn Sina, Book I.) According to the Turkish Kamis, it is the leaf of a sweet-smelling plant Hed o|,s/Ua .» (locust’s foot). Sprengel thought it was ' Salix Afgyptiaca. (Confer. Hist. rei. herb., T. IL., p. 270.) Zarnab is of the measure Wx? and is a genuine Arabic word. _ A rajiz says— wi! dale y4 Gi quell S35 a) | wil lL O with my father thou shouldst be ransomed, and thy mouth, that is cool and sweet, as though Zarnab were sprinkled upon it.” (Sihah.) In the tradition of Umm Zara, where it is said wi} 4) gu 15 1 mo (wel! “the feel is the feel of a hare, and nn ae: is the odour of Zarnab,”’ Ibn el Athfr, author of the Nihayeh, says that it signifies saffron (Madd-el-kamis). Ainslie (ii., 407) considers Talispatar to be the leaves and twigs of Flacourtia cataphracta, Roxb. Dr. U. C. Dutt,in his Hindu Materia Medica, states that the Télispatar of the Calcutta shops consists of the leaves and twigs of Abies Webbiana, Lindl.* Dr. Moid{n Sheriff gives the name of T4lishapatri to the leaves of Oinnamomum Tamala, Nees. It would appear, therefore, that it is uncertain at the present time what the Télisapattra of Sanskrit writers is, and that in different for it. * Webb’s or purple-coned fir, parts of the country various drugs are used as substitutes 376 CONIFER. All the samples of the drug which we have obtained from Bengal, Northern, Western and Southern India have consisted of the leafy twigs of the yew chopped in lengths of from one to two inches. The yew was known to the Greeks and Romans as a poisonous plant.* Modern enquiry has shown that the leaves and seeds are poisonous, but not the red pulp surrounding the latter. The leaves have, however, been recommended in doses of from 1 to 5 grains in epilepsy and other spasmodic affections. As an abortive they have been often administered, and have generally proved fatal to the woman, without causing the expul- sion of the foetus. Moderate doses given to animals occasion hurried breathing and palpitation of the heart, followed by recovery, and larger doses produce a similar effect followed by death from syncope. Very large doses appear to produce death by syncope without pain or spasm. According to Borcher’s (1876) experiments, taxine reduces the pulse and respirations and causes convulsions, with fatal asphyxia. (Husemann.) After death the evidences of gastro-intestinal inflammation have generally been slight, the heart was usually empty, the kidneys strongly congested, and the blood less coagulated than usual. The effects produced upon man by poisonous doses of yew resemble those above mentioned as occurring in animals: after large doses the nervous irritation, exhaustion and gastric disturbance may be very trifling, the patient dying by syncope. Description.—The drug consists of the small branches of the tree with their linear-lanceolate, narrow, rigid veinless leaves cut up into short length (1 to 2 inches). The male flowers are to be found upon some of the sprigs, and resemble those of the common yew. The wood of the larger stems is that of a yew, and not of a pine. Chemical composition.~-Statements have been made at differ- ent times as to the presence in the leaves and fruit of the yew (Taeus baccata) of an alkaloidal principle. In 1876 (Pharm. : * ragos and ow:Aag. Dios. 4, 80; Plin. 16, 20. CONIFER. 877 rn., [3], vil., 894), Marmé described a crystalline alkaloid at he had separated from the leaves and fruit, which he med ‘‘tawine,’ and spoke of as being poisonous. It was ined by treating an ethereal extract of the leaves and ith water acidulated with sulphuric acid and precipitat- this solution with ammonia. Messrs. Hilger and Brande erichte, xxiii., 464) that, working on the leaves in the vay, they have separated an alkaloid, which they failed lize. ‘This taxine melted at 82° C., and when heated lass tube gave off white fumes that condensed on the parts of the tube to oil-like drops that solidified on g, at the same time a characteristic aromatic odour was ved. It dissolved in water in traces only, freely in 1 alcohol ents, and white precipitates, insoluble in excess, wit fixed alkalies and ammonia. The salts of taxine are tly readily soluble in water, but only the hydrochloride ined well crystallized, and this by passing a current 1ydrochloric acid gas into a solution of the alkaloid in ydrous ether. Analysis of taxine gave results correspond- with the formula C57H°*O'N, and its behaviour with ethyl (Pharm. Journ., Mar. 29, 1890.) _ Towicology.—No cases of poisoning by this plant have been recorded in India, but considering its common use as a dru roughout the country, we cannot help suspecting that such cidents must have happened, especially as the native doctors do not appear to be aware of its poisonous properties. Several cases of poisoning by yew have occurred in England, most of which have ended fatally. The prominent symptoms were vomiting followed by narcotism, with, in some cases, convulsions and dilated pupils, respiration slowed; death usually by phyxia, due to paralysis of the respiratory muscles. i IIL.—48 378 CONIFERS. PINUS LONGIFOLIA, Rozt. Fig.—Royle Ii., t. 85, f.1; Griff. Ic. Pi. Asiat., tt. 369, 370. Hab.—Outer Himalayan Ranges, The turpentine. Vernacular,—Saral, Chir (Hind.), The turpentine, Ganda- biroja (Ind. Bazars). History, Uses, &c.—The wood, in Sanskrit Sarala, and the turpentine Sarala-drava, are mentioned as medicinal in Sanskrit works; plasters, ointments, and pastiles for fumi- gations are directed to be made from the turpentine. The latter, under the name of Ganda-biroja, or, more correctly, Gandah- birozah, is found in all the Indian bazars, and appears to have all the properties of ordinary turpentine, though differing from it — in odour. It is chiefly used as a pectoral plaster like the pitch plaster of Europe, but it has also a reputation in veterinary practice as a remedy for mange. The Vaids obtain from it by distillation without water a limpid sherry-coloured oil having the peculiar odour of the drug, which they call Khanno oil in the Deccan; it is in much repute as a remedy .for gleet or long-standing gonorrhea. Collection.—The Chir Pine, which is a large treeof Afghan- istan and the North-West Himalayas, is the chief source of this turpentine. Atkinson, who describes its collection in Gurhwal and Kumaon, says that it is there called Birja and Lisha or Lassa,* and that there are two kinds collected, vi, _ the natural exudation and Bakhar-birja,t which is obtained by making incisions in the sap-wood. The yield of a tree thus treated is said to be from 10 to 20 lbs. the first year, and about one-third the quantity the second year, after which the tree either dies oris blown down. (Atkinson, Brandis.) & rer lasé ; Tit. Jasha ; any viscous exudation of plants. : ‘Tas, aTet, or 4H an enclosure, house, chamber. An allusion to CONIFERS. 3879 Description.—Gandah-birozah is a dirty-white opaque mbstance, of soft and sticky consistence, having a strong and culiar odour, more aromatic than that of common turpentine ; ; leaves of some tree, which have evidently been used in cting the turpentine, are usually found mixed with it in nsiderable quantity. nical composition.—56. lbs. of the crude drug distilled water yielded 8 lbs. of a colourless. limpid oil, having the iar odour of Gandah-birozah. The resin remaining in the was of a dull brown colour; after straining to remove im purities it was stirred with a small quantity of boiling water ntil hard, and afforded a very fair substitute for Burgundy Pitch, weighing 43 lbs. The oil, according to Lyon, has a specific gravity of -875 at 82° F.; it commences to boil at about 310° F., and is dextro- otatory. Pinus Khasyana, the Khasya Pine of Assam, yields a e quality of turpentine. A full-grown tree gives as much as Tbs. of crude resin a year. The oil is very pure, and Dr. strong in 1881, reported that it had the greatest amount action on polarized light of any coniferous oil of turpentine e had examined. Pinus Gerardiana, Wall. Lamb. Pix. Ed. 3, t. 79; oyle Ill. 353, t. 85, f. 2; Cleghorn Pines of N.-W. Himal., t, 4, a native of Afghanistan and Persia, yields the pine-nuts which, are sold in the Indian bazars under the name of Chilyhozeh, and are described in Mohometan medical works under the Arabic ame of Hab-el-sanaubar-el-kibar. In Persia the tree is called (+) and in Afghanistan C/i/ and Zan-ghozeh. Aitchison (Notes on Prod. of W. Afghanistan and N,-E. Persia, p. 152) ‘states that the seeds are one of the great trade products: exported from the district of Kost and the Kuram Valley to ndia; they have stimulating properties, and are considered ‘useful in chronic rheumatic affections, and as.an aphrodisiac. ‘b 7 are usually administered pounded with honey, in the orm 880 CONIFERA. of a confection; they are of a brown colour, about one inch in length, and have an oleaginous and terebinthinate ayour. - Church, “Food Grains of India,’ found the percentage : composition of the seeds to be Water 8°7, Albuminoids 13°6, Starch 22:5, Oil 51°3, Fibre 0-9, and Ash 3:0, CEDRUS LIBANI, Barrel. var. Deodara. Fig. — Hook. f. Nat. Hist. Rev. ii., t. 1-3; Forbes, Pinet. Wob., t. 48, 49; Griff. Ie. Pl. Asiat., t. 364. Hab,—N.-W. Himalaya. The wood. Vernacular.—Deodar-ki-lakri (Ind. Bazars). History, Uses, &c.—This tree, in Sanskrit Devadaéru, Suradéru, Suradruma ‘‘tree of the gods,” yields the Bhadra- ashtha “auspicious wood,” Sneha-viddha “impregnated with oil,” which is used as acarminative, diaphoretic, and diuretic by = the Hindu physicians in fever, flatulence, inflammation, dropsy, _ urinary diseases, &c. It is chiefly used in combination with other medicines, as in the following diuretic mixture: —Take of Devadéru wood, root of Moringa pterygosperma (Sigru), and Achyrantes aspera (Apamarga), one drachm each and reduce to @ paste with cow’s urine. To be given in ascites. (Chakradatta.) The wood is also ground toa paste with water and applied to the temples to relieve headache. A tar (Hilan-ka-tel) made by destructive distillation of the wood is a favourite remedy for sases in Northern India; it is given internally in doses 1t one drachm, and also applied locally. From the =, name Devad4ru of this wood, it must not be confounded Wit the wood of Erythrorylon monogynum, known in Tamil as vadarum, and which, on aceount of its bedbars! is called “ — oa di 7 ear CONIFERS, ase cae rin (Afghanistan) to tan leather (he doubtless alludesto the which is used in the Punjab to dress the inflated skins used crossing rivers). Description.—The wood sold in the bazars is of a light sllowish-brown colour, very heavy, and in thin sections trans- nt, owing to the large proportion of turpentine contained in has an agreeable terebinthinate odour. paration of the tar.—First, an earthen vessel (ghara), with the ground. Next, a large ghara of about 12 seers’ capacity taken, and three small holes are drilled in its underside ; it is then filled with scraps of the wood, and over its mouth another smaller jaris placed, and kept there by a luting of clay; and then both the jars are smeared over with a coating he clay. These two jars thus stuck together are next set on the mouth of the receiver sunk into the ground, and the jointis | e tight by clay. Firewood is now heaped round the apparatus and lighted, and kept burning from four to eight TS. e jars are then separated ead the tar removed. One seer (2 pounds) of wood yields about 2:6 chittaks (54 ces) of tar. (Baden-Powell, Punjab Prod.) Chemical composition.—An alcoholic extract of the wood was taneously evaporated to dryness by exposure to air, and the extract agitated with petroleum ether, and the insoluble residue treated with caustic soda and agitated with ether. _ The petroleum ether extract on spontaneous evaporation left a transparent, pale yellow varnish-like residue, with a ve fragrant terebinthinate odour, which became hard on exposure in thin layers, but preserved a perfect transparency. This extract was treated with aqueous caustic potash and agitated, with ether. The mixture after standing separated into three layers, The lowest stratum was of a reddish yellow colour, the middle darker in colour, and the small amount which floated layer on spontaneous evaporation, left a satiny mass of fragrant t odour, which, on microscopic examination, consisted of in I above the ether of a bright light yellow tint. The ethereal = 2 882 CONIFER. needles and narrow plates. On ignition an alkaline ash was left. In sulphuric acid it dissolved with a yellow colour, no change being induced by the addition of nitric acid to the solution or hydrochloric acid and phenol. In order to obtain this resin acid in a free state, an ethereal sojution of the potash salt was agitated with dilute sulphuric acid. On spontaneous evaporation of the ether, the acid was left as a transparent varnish. The middle layer mentioned above appeared to consist of a concentrated solution of the potash salt of the resin acid ; the potash salt not being very readily soluble in ether. The aqueous stratum was treated with sulphuric acid and agitated with ether, the ethereal extract was yellow, and had a slight odour not unlike that of valeric acid. That portion of the original alcoholic extract insoluble im petroleum ether, was now agitated with ether and aqueous potash. The ether left on spontaneous evaporation a transparent yellow extract, insoluble in water; soluble in alcohol with neutral reaction, and possessing a marked bitter taste. Sulphuric acid coloured the extract a bistre-red. The potash solution was mixed with sulphuric acid and agitated with ether; during agitation dark reddish flocks separated, which were insoluble in ether even after prolonged agitation. The ethereal solution left a yellow transparent residue. In alcohol the extract was. soluble with bitter taste and acid reaction. In concentrated sulphuric acid it dissolved with a dark-red colour, the addition of concentrated hydrochloric acid afforded a colour of crushed _ strawberries, which became of a reddish violet on the addition = of phenol phenol. In aqueous potash the extract dissolved with a bright yellow lisation. Ferric chloride added to an alcoholic solu- _ tion gavea dirty brown coloration. The flocks insoluble in u ether, were of a ' reddish- brown colour, brittle when dry, without = lic solution, acid in reaction, and affording - similar reactions with sulphuric and hydrochloric acids and ‘ —_ ee ferric chloride and caustic potash, to the resin CYCADACEH, 383 CYCADACE. CYCAS CIRCINALIS, Linn. Fig.—Richard, Conif., t. 24—26; Bot. Mag., ¢. 2826 and 2827; Rheede, Hort. Mal. iii., 9, t. 13—21. : ab.—Malabar Coast, Dry Hills in W. Madras. Male and flour. | ernacular.—Jungli-madan-mast-ka-phul ( Hind.), Madana- kama-pu, Kamappu, Chanang kay (Zam.), Rinbadam, Todda- pana Eentha kay (Ma/.), Malabdri-supari (Mar.). 3 History, Uses, &c.—The male bracts of this tree are used in Southern India as a narcotic, and are considered to be similar in medicinal action to the flowers of Stereospermum sua- veolens. Both drugs are termed Madana-kama-pu or flowers of Malabar the nuts are collected and dried for a month in the n, beaten in a mortar, and the kernels form a flour which is called Indum Podi. It is reckoned superior to the flour of Caryota, but inferior to rice, and is only eaten by the hill-tribes, and by the poorer classes, who, from July to September, when rice is scarce, are in danger of perishing. It has often been confounded with true sago. Rheede states that the fruit bearing cone reduced to a poultice and applied to the loins removes nephritic pains. Description.—tThe bracts as sold in the bazar are of the shape of a spear head, two inches long by half an inch broad, clothed at the back with much fulvous down. A subulate incurved point rises from the exterior upper angle of each of the scales. When the strobile first appears, they are closely _ pressed together like the germs in the pineapple, but as it lengthens by age, they become detached from each other. Filaments none; the anthers entirely covering the under : fac 884 3 ORCHIDE#. of the scales, one-celled, two-valved, opening round the apex on discharging the pollen. The starch of the pith resembles that of sago under the microscope. Chemical composition.—The bracts or scales contain, in a dried state, much albuminous and mucilaginous matter soluble in water, but no alkaloid or other principle that would account for its reputed narcotic action. ORCHIDE/L. ORCHIS LATIFOLIA, Linn. Fig.—Fl. Br. 924; Engl. Bot. 33., ¢. 2308; Reichb, Fl. Germ. «iii., 50. Marsh Palmate Orchis (Eng.). : Hab.—Persia, Afghanistan, Nepal, Cashmere, and Europe. ORCHIS LAXIFLORA, Lam. Fig.—? Boiss. Fl. Orient. v., p. 71. Hab.-—Persia and Afghanistan. The tubers. Vernacular.—Salab-misri, Salap-misri (Hind.), Shalé-mishiri (Tam.), S4lé-misiri (7el.}, Séli-mishri (Had.), Chéle-michhri S (Beng.), Salama-misri (Mar., Guz.). ae _ History, Uses, &c.—Theophrastus (P. H. ix., 19), and a Siete (iii., 132, 183, 184, 135), mention several tuberous — eee Rug ahich were cot by the Greeks under the names of Orchis — és = i It is not known exactly what all of dae were, but it is certain that some of them were the tubers | of different species of Orchis. Opxis is described by the ancients as having ; a twofold root, formed of tuberosities which resemble the testes in appearance. The larger of these tuberosities, or, some say, the harder of the two, taken in water, was thought 3 ovocative of of lust; while the smaller, or, « - to falc in goat aly was considered be ORCHIDELR. -autaphrodisiac. The tubers were also used as a remedy for alcerations of the mouth and pituitous discharges —_ the est, and were taken in wine as an astringent. _- Mahometan physicians describe Orchis tubers under the name of Khusyu-uth-thalab (or salab), ‘foxes’ testicles,” and state that ‘She odour of them, when fresh, resembles that of semen hominis, hat they have an aphrodisiac effect if clasped in the hand. ried tubers have a great reputation in the East asa nervine — onic and restorative, and are much prescribed in. paralytic affections. It was formerly supposed that Oriental Salep was ebtained from certain species of Eulophia, but the tubers of these plants have no resemblance to the commercial article, and Aitchison has now established the fact that the two plants ~ placed at the head of this article yield the bulk of the Persian salep. Eulophia campestris, Wall., is, however, used locally in Northern India as a substitute for salep. In Southern India the tabers of several species of Habenaria and Orchis are collected by people in the hilly districts and | sold locally as salep, but they are usually small and variable 1 appearance. Salep is now regarded in Europe as very nutritious; it tends to confine the bowels, and is, therefore, a useful article of ciek for those who suffer from diarrhea. : The mucilage is prepared by first macerating powdered salep in cold water, and gradually adding boiling water, with stirring, in the proportion of 5 grains of salep to the ounce. Instead ef water, milk or some animal broth may be used. Salep jelly may be made as follows: Rub 60 grains of powdered salep with water in a mortar until it has swollen to four times” its original bulk; then add gradually, and with constant _ stirring, 16 ounces of boiling water, and boil down to 8 ounces, Ainslie states that salep has the property of depriving salt- water of its salt taste. Description.—Oriental_ salep is of two kinds, palmate — and ovoid; the former, which was once known in Euro ope Radiv palme. Christi, is very highly esteemed oY. the P ~~, TL —49 found the 386 ORCHIDEZ. especially if of large size. The ovoid tubers are from 1 to 19 inches in length, and, if of good quality, have a creamy white colour, or are somewhat translucent and of a horny texture. They have hardly any odour and an insipid mucilaginous taste. - The tubers should be plump and not wrinkled. When magni- fied, the bulk of the tuber is seen to consist of a parenchyme, the cells of which contain either mucilage, or starch altered by heat ; it is traversed by small fibro-vascular bundles. Chemical composition.—The most important constituent of salep is a sort of mucilage, the proportion of which, according to Dragendorff (1865), amounts to 48 per cent. ; but it is, doubtless, subject to great variation. Salep yields this mucilage to cold water, forming a solution which is turned blue by iodine, and mixes clearly with neutral acetate of lead like gum arabic. On- addition of ammonia, an abundant precipitate is formed. Muci- lage of salep precipitated by alcohol and then dried, is coloured. violet or blue, if moistened with a solution of iodine in iodide of potassium. The dry mucilage is readily soluble in ammo- niacal solution of oxide of copper ; when boiled with nitric acid, oxalic, but not mucic, acid is produced. In these two respects, the mucilage of salep agrees with cellulose, rather than with gum arabic. In the large cells in which it is contained, it does not exhibit any stratification, so that its formation does not appear due to a metamorphosis of the cell-wall itself. Mucilage of salep contains some nitrogen and inorganic matter, of which it is with difficulty deprived by repeated precipitation by alcohol. It is to the mucilage just described that salep chiefly owes its power of forming with even 40 parts of water a thick jelly, _ which becomes still thicker on addition of magnesia or borax. The starch, however, assists in the formation of this jelly; yet its amount is very small, or even ni/ in the tuber bearing the flowering stem, whereas the young lateral tuber abounds in it. None starch so deposited is evidently consumed in the subsequent period of vegetation, thus explaining the fact that tubers are e decoction of which is not rendered blue by iodine. Salep contains also uga and albumin, and, when fresh, a trace ORCHIDEA. 887 isting chiefly of phosphates and chlorides of bible and cium. (Pharmacographia.) Gans and Tollens have tested e oxidation products, and in Annales, 249, 245 (J. Chem. Soc., 1889), they report : “On oxidation salep yields saccharic y crystallization from the seas © compounds of and mannose, ime which show that the syrup gone tities, and is much more highly valued than the latter ; in rsia it iscalled Panjch-i-sdlab, or “ hand salab,” a name whic is corrupted into Punjébi in India. The ordinary salep of commerce is known as Abushaheri or lasaniya, ‘garlic-like”’; it at Rs. 30 to 35 per maund of 41 lbs., according to quality, the palmate variety fetches fancy prices; if very fine d white, from 5 to 10 rupees per lb. may be asked for it. ee of Madras is largely supplied from the Nilgiris, it is collected by the Todas and other hill tribes. The are boiled in water, and then dried in the sun until quite rd, and are sent into the market in coarse bags containing 2maunds. In Ootacamund this salep sells for Rs. 5 to Rs. 6 maund of 25 Ibs., and in Madras it realizes about twice the rice. Mahomedans all over Southern India use this salep for making conjees and the sweetmeat hudwa. - Imitation salep is largely manufactured in India; it is known Banawati salad or salam, and is said to be made of pounded toes and gum. EULOPHIA VIRENS, Er. _ Fig.— Bot. Reg., ¢, 573; Wight Ic., t. 913; Bot. Mag., t. 5579; Roxb. Cor. Pl. i., t. 88; Rheede, Hort. Mal. zii., tt. be 26. Hab.—Bengal and Deccan Peninsula. 388 ORCHIDE. EULOPHIA CAMPESTRIS, Wail. Hab.—Plains of India, Punjab, Oudh, Bengal, and Deccan. EULOPHIA NUDA, Lindi. Fig.— Wight Ic., t. 1690; Rheede, Hort. Mal. wit., t. 26° Hab.—tTropical Himalaya and Deccan Peninsula. The tubers. Vernacular.— Mén-kand, Amber-kand, Bhui-kékali (Mar.), Katou-kaida-maravara, Katou-theka-maravara (Ma/.), Budbar, — (Beng.), Goruma (Hind.). History, Uses, &c.—The tubers of these plants are used indiscriminately by the natives. The vernacular name Man- kand is derived from the Sanskrit Manya, which signifies “ the neck,” and the plant is so named from a supposed resemblance between its tubers and scrofulous glands in the neck ; Mén (ar), the Marathi form of the word, is also applied to the scrofulous - disease in the neck. The tubers are applied externally and given internally to remove the disease. They are also adminis- tered internally to those suffering from intestinal worms. Rheede says of #. virens :—“Succus radicis si supra arborem Kansjira inveniatur amarus est, alvum laxat, bilem promovet. Succus bulbi et foliorum omnem adustionem ex pulv ere pyrio, oleo ferventi, vel igne causatam, cum sanguine canino mixtus,. llit. Pulvis venenum, sive externum sive internum expellit.. Si supra arborem Java, vermes intestinorum enecat, febri resistit, ventriculum corroborat, flatus dissipit.. Succus cum carne : totius plantee in formam cataplasmatis redactus apostemata - emo it, et, sine dolore, ad maturitatem producit.” Roxburgh describes FE. virens under the name of Limodorum virens, but 2 _ does not notice its medicinal usés: Aitchison (Notes on Pro- duets of W. Loe ap and N. E. Persia, p. 68) says :-—“ E. cam- — is by y ho means rare in the Punjab, Baluchistan, and : S di . he — are collected in the Punjab, and make nary Salep of Lahore. When the present railway ; the © is ab, at Wazirabad, 6 ORGHIDEM, | 389 some of the islands over which the bridge was built were one season covered with this Orchis, specimens of which were sent to me by Captain Clerk, and which are now in the Herbarium at Kew.” preliminary experiments indicated that when ied for — with an ERT en TOGO Rae Fs teen Cente ae a ih tial as eR ida ti ath ae + ORCHIDE. 395 aqueous solution of the alcoholic extract, the liquid formed an emulsion which showed little or no tendency to separate. The amylic alcohol tincture was evaporated on a water bath, and, when dry, was repeatedly agitated with ether, until colouring matter ceased to be dissolved. The extract insoluble in ether was then redissolved in amylic alcohol and agitated repeatedly with baryta water, until the baryta water ceased to be colored yellow. During agitation a soft varnish-like mass separated and adhered to the sides of the bottle. By this treatment the originalamylic alcohol extract was separated into three fractions: (1) The amylic alcohol solation, (2) the varnish-like residue adhering to the sides of the bottle, and (3) the baryta water Bolittion. (1) The amylic alcohol solution on evaporation left a solid residue, which, after being pounded, and agitated with ether, to remove traces of adherent amylic alcohol, possessed the proper- ties of a saponin-like principle; it frothed considerably with water; treated with concentrated sulphuric acid, adirty reddish coloration was slowly developed; in water and aqueous ammonia it was only slightly tokible, but dissolved easily in ordinary acetic acid. As extracted the eee was not pure, it contained colouring matter and barium (2) The varnish-like residue was dissolved in acetic acid and agitated with amylic alcohol, the extract being treated with ether to remove traces of amylic alcohol. This extract also behaved like a saponin-like principle: after purification it formed a yellowish powder, it frothed considerably with water ; treated with concentrated sulphuric acid, it developed in a shorter period than the first extract a beautiful bright carmine coloration: in water it was easily soluble, a concentrated solution having much the physical appearance of an aqueous egg albumen, and it dissolved readily in aqueous ammonia. : (3) The baryta water solution contained much colouring matter and a small amount of a principle which frothed with water, which was probably a mixture of the two principles already mentioned. 396 SCITAMINE. The original aqueous solution of the alcoholic extract, left after agitation with amylic alcohol was acidulated with acetic acid and agitated with ether. The ether extract contained a neutral resin-like principle, a very bitter resin acid, the bitter taste of the drug being probably due to this resin, and a white crystallizable acid. Finally, the acid aqueous solution was treated with sodic carbonate in excess and reagitated with ether. The ether separated traces of an alkaloidal principle, which afforded a faint yellow coloration with Fréhde’s reagent, deeping slightly on heating, Vanda spathulata, Spreng., is the Ponnampou-mara- cara of Rheede (12, 3), and is supposed on the Malabar Coast to temper the bile and abate phrenzy, and the golden yellow flowers, reduced to powder, are given in consumption, asthma, and mania. (See Ainslie, Mat. Med., ii., 321. - Rhynchostylis retusa, Blume, is also mentioned 2 Rheede (xii., 1), also Cymbidium tenuifolium (xi, and 6) and C. ovatum (xii., 7), as emollients. C, ee (xii., 8) is said to be emetic and purgative. SCITAMINEZ. CURCUMA AROMATICA, Saiisé. iS ‘Fig. —Salish. Parad., t. 96; Rose. Scit., t.103; Wight Le., 2 ee Bot. Mag., t. 1546. Wild Turmeric, Yellow Zedoary, Ce Turmeric (Enz.), Zedoaire jaune (F7.). - —Throughout India, wild and cultivated. The jangli- haldi, Ban-haldi (Hind.), Ban-halad > -halad sind ae halad OTE SOITAMINEA. 97 History, Uses, &c.— This plant is the Vana-haridra or ‘‘ wild turmeric” of Sanskrit writers. The Arabian and Persian physicians do not notice it, and probably did not distinguish it from turmeric. Roxburgh and Ainslie wrongly supposed it to _ __ be the Jadwar of the Arabians (see Vol. I., p. 20). It is the turmeric-coloured zedoary of Ainslie, who states that the Mahometans of Southern India suppose it to be a valuable medicine in snake-bite, administered in conjunction with golden ‘orpiment, costus, and ajwain seeds. Guibourt (ii, p. 214) calls it Zedoaire jaune, and states that the plant which produces it has been well described and figured by Rumphius, and is his Tommon bezaar or Tommon primum, which has been wrongly referred by most writers to the Curcuma Zedoaria of Roscoe. C. Aromatica is identical with the Cassumunar described by Pereira (Mat. Med., Vol. II., Pt. I., p. 236), and the “ Cochin Turmeric” noticed by Fliickiger and Hanbury (Phar- macographia, p. 580). The properties of this drug are very similar to those of turmeric, but its flavour being strongly eamphoraceous i is not soagreeable. It is used medicinally by the Hindus, in combitiation with other drugs, as an external application to bruises, sprains, &c., and is applied to promote the eruption in the exanthematous fevers; it is seldom used alone, but is combined with astringents when applied to bruises, and with bittersand aromatics to promote eruptions ; it is never prepared from the tubers in Travancore. The plant under favourable circumstances produces central tubers as large as a small turnip. One of us has had it under cultivation for some years; the leaves when young have a central purple stain, which almost disappears when they attain their full size. The flowers appear in May or June, with the first leaves, just before the the rainy season. Description.—Central rhizome oblong or conical, often more than two inches in diameter, external surface dark-grey, marked with circular rings and giving off many thick rootlets ; at the ends of some of them are orange-yellow tubers about the size and shape of an almond in its shell; lateral rho about used as a condiment in India, but a kind of arrowroot is 398 SOITAMINE A. as thick as the finger, with a few fleshy rootlets. Internally both central and lateral rhizomes are of a deep orange colour like turmeric ; the odour of the root is strongly camphoraceous. Microscopic structure.—Similar to that of turmeric. Chemical composition.—The drug yielded to analysis :— Ether extract (essential oil, fat, and soft resins)... 12°06 1 Alcoholic extract (sugar, resins) sy ee Water extract (gum, acids, &c). 6:50 Starch ee See Crude fibre cae 8°42 Ash.. 4°46 Moisture : 13°33 Albuminoids, 1nodifications of arabin, &c. ..,...... 30°63 100°00 - The root had an odour of ginger; curcumin was present. The water extract gave a crystalline precipitate with lead - acetate, which was found to be due to the presence of malic acid. Commerce.—The plant is chiefly grown at Alwaye, North- east of Cochin, and is also collected in Mysore, Wynaad, and _ other localities in Southern India for export to Europe asa substitute for turmeric to be used in dyeing. It is exported from Cochin and Bombay. Value, Rs. 24 to 25 per candy of 53 ewts. for the unpeeled root, Rs, 27 to 28 when peeled. A European firm of Druggists in Bombay, writing to London for the ingredients to make Warburgh’s fever tincture, was supplied with this article as Zedoary. Exports of Turmeric from Cochin :-— Europe, &e. India, Burma, &c. Total ewts. 1884-85 ...... 5,154 6,361 11,515 - 1885-86. ......- 7,610 2,776 10,386 ORES... 6,081 1,967 7,998 oe SOROS 3 : 4,395 Geoscience 8 ee 2,276 tle SCITAMINE. | 399 CURCUMA ZEDOARIA, Ros. Fig,— Rose. Scit., t. 109; Roxb. Cor. Pl., t. 101; Rheede, Hort. Mal. wi., t. 7. Zedoary (Eng.), Zedoaire (f7r.). Hab.—Eastern Himalaya, cultivated throughout India, The tubers. Vernacular.—Kachtra (Hind., Beng., Mar., Can., Guz.), Kichilick-kizhanghu, Pulan-kizhanga (Zam.), Kichili-gaddala, Kachoram (Ze/.), Kacholam, Kachuri-kizhanna, Pula-kiz- hanna (Mai.). History, Uses, &c.—This plant is the Sati and Kra- ~ ehura of Sanskrit writers, and the Zerumbad and Urik-el-kafir, “camphor root,” of the Arabians. It is noticed by the later _ Greek physicians under the name {ovpop3ed, a corruption of the Arabic name, which, in the Middle Ages, was variously written as Zeruban, Zerumber, and Zerumbet. It is not the ¢é80ap of ZBtius (A. D. 540—550) or the r¢erdvapiov of Myrepsus, or the - Zedoar of Macer Floridus (A. D. 1140). Barbosa (1516) speaks of Zedoaria and Zeruban as distinct articles of trade at Cannanore, so that it must have been some time after this date that Zerumbet came into use in Europe as a cheap substitute for the _ Zedoar of the earlier physicians, which, we have no doubt, was the same drug as the Jadwar of the Arabians. This name, correctly written by Altius, is the y!5 o5 (Zhedwar) of the ancient Persians, and is described in the Burhdn (A. D. 1046) as a drug used as an antidote to poisons, the same as the Jadwar of the Arabians, and also called Mahparvin. Ibn Sina of Bokhara, who lived about the same time (980—1037), _ describes Jadwé4r shortly in the following words :— dio Gol, oaigl idee ebd sre lJ! —“it has the form of the root of Aristolochia, but is smaller.” Haji-Zein-el-attar, the well-known Persian physician and apothecary, and the author of the “Ikhtiarét” (A. D. 1368), describes Jadwar asa - root about the size and shape of the Indian Cyperus root, but the best internally of a purplish tint. He states that harder and heavier, and the same as the Indian drug Nirbisi, — 4 4.00 SCITAMINEA,. are, as far as his experience goes, four drugs sold as Jadwar, viz., a white kind, a purplish, a black and a yellow ; the people of Cathay call the yellow kind Auwrti and the purplish Burbi, the other two kinds come from India. As to the locality in which the drug is collected, he states that there is a mountain ealled Fardjal between India and Cathay, where the plant grows along with the aconite, and that the latter, whenever it grows near the Jadwar, loses its poisonous properties and is eaten with impunity by the inhabitants. Where the Jadwar does not grow, the aconite (Bish) is a deadly poison, and is called Hadléhal by the natives (Halahala, Sanskrit). In the Dict. Econ, Prod. of India (ii., p. 656), the following interesting account of certain drugs collected in Nepal by Dr. Gimlette, the Residency Surgeon, substantially confirms Haji-Zein’s description of Jadwar or Nirbisi :—According to Dr. Gimlette, ‘the Kala bikh of the Nepalese (the Dudingi of the Bhoteas) is a very poisonous form ef Aconitum ferox, so poisonous, indeed, that the Katmandu druggists will not admit they possess any. Pah/o (yellow) bikh is a less poisonous form of the same plant, known to the Bhoteas as Holingi, while Setho (white) bikh (the Nirbisi sen of the Bhoteas) is A. Napellus, and Atis is Aconitum hetero- phyllom. The aconite adulterants or plants used for similar purposes are, Cynanthus lobatus, the true Nirbisi of N epal, the root of which is boiled in oil, thus forming a liniment which is employed in chronic rheumatism, Delphinium denudatum, the Nilo (blue or purplish) bith of the Nepalese and the Nirbisi of the Bhoteas, Dr. Gimlette says, is used by the Baids of Nepal for the same purposes as the Setho and Pahlo bikh. Geranium _ eollinum (var-Donianum) is the Ratho (red) bikh of the Nepalese, and the Nirbisi-nwm of the Bhoteas, and, like the Setho bikh, is given as a tonic in dyspepsia, fevers, and asthma. Lastly, a plant never before recorded as used medicinally, namely, Caragana crassicaulis, is known as the Artiras of the N epalese, end the Kurti of the Bhoteas; it affords a root which is : Ske as a febrifuge.” The Jadwir or Nirbisi myth appears to have been invented = ‘the East: to ut for the curious occurrence on the SCITAMINES. 401 Himalayas of poisonous and non-poisonous aconites growing de by side (see Vol. L., pp. 1, 15, 18, 20). It would appear also that the Curcumas have no claim to the name of zedoary, which was probably first given to them about the middle of the 16th century, as Clusius’s figure of Gedwar is certainly meant for the pendulous tuber of a Curcuma. The substitution of the cheaper for the more expensive article is ndered highly probable by the fact that Zerumbet was con- sidered by the Arabians to be very little inferior to Jadwar as an “antidote to poisons. Ibn Sina, Ibn Baitar, and Ibn J azla in the Minhdj use almost the same words in speaking of these drugs ; of adwar they say — sell gp ma | ste Lye b prod! Gly) 97, “it : is an antidote for all poisons, even those of aconite and the viper’’; and of Zerumbet —)! 9o=) 14 ste 1Oe p ladle SM ez Wy? “it is most useful against the bites of venomous animals, and is almost equal to Jadwar.”” Both drugs were considered to have properties similar to Darunaj (see Vol. II., p. 292). . Ainslie (Mat. Ind., i, 492) remarks that C. Zedoaria is the Lampooyang of the Javanese, and the Lampuium of Rumphius (Herb. Amb, V., p. 148), and that itis a native of the East Indies, Cochin- China, and Otaheite. He quotes Geoffroy’s description of the drug, which leaves no doubt as to its identity with the modern hora—‘ Foris cinerea, intus candida; sapore acri-amaricante romatico; odore tenui fragrante, ac valde aromaticum suavi- tatem, cum tunditur aut manducatur, spirante et ad camphoram _ aliquatenus accedente.”” Guibourt states that O. Zeg@oaria is the — Zerumbet of Serapion, Pomet, and Lemery. The following is his description of it :—‘“ The round zedoary is gre yish-white externally heavy, compact, grey and often horny internally, having a bitter and strongly camphoraceous taste, like that of the long zedoary, which it also resembles in odour. The odour of both drugs is analogous with that of ginger, but weaker unless the rhizome be powdered, when it developes a powerful aromatic odour, similar to that of cardamoms.’”’ (Hist. Nat. gme. Ed., Vol. II., p. 213.) In our opinion there is no doubt that C. Zedoaria is the source of the round and long zedoary — of commerce. The plant is common in Bombay gardens, nd >». IIL—S5l 4.02 SCITAMINEA. was probably introduced by the Portuguese, whose descendants and converts at the present day use the leaves in cookery, -especially with fish. From Dr. Hové’s account of Bombay in 1787 it appears that Kachtra and Turmeric were cultivated at that time in the cocoanut woods at Mahim. The natives chew the root to correct a sticky taste in the mouth; itis also an ingredient in some of the strengthening conserves which are taken by women to remove weakness after child-birth. In colds it is given in decoction with long-pepper, cinnamon and honey, and the pounded root is applied as a paste to the body. Rheede says that the starch of the zedoary is much esteemed, and that the fresh root is considered to be cooling and diuretic, it checks leucorrheal and gonorrheal discharges and purifies the blood. The juice of the leaves is given in dropsy. One of us has had the plant in cultivation for some years; it blossoms in the hot weather just before the rains, when the first leaves begin to appear. Description.—Guibourt’s description already given agrees exactly with the Kachiira of India, but it is often cut into transverse slices instead of into halves and quarters. Microscopie structure.—This is essentially the same as that of turmeric, but the resin and essential oil in the cells is of a yellowish-white colour, and the greater portion of the starch grains are ovoid or pyriform, instead of narrow and elongated as in turmeric, Chemical composition.—Zedoary contains, according Bucholz (Repert. Pharm. xe., 376), volatile oil, a bitter soft resin, a bitter extractive matter, gum, starch, &c. The oil is_ turbid, yellowish-white and viscid, has a camphoraceous taste and smell, and consists of two oils, one lighter, the other heavier than water. Trommsdorff obtained from the root a substance which he called Zedoarin, but did not further describe it. A proximats analysis afforded :— ential oil, resin, cureumin, &e.. Maspes use. Oe , stigar ......., -90 (Gum ana orga rgan acids . 17-20 Nsiweks ay 15°22 SCITAMINEZ. 403 Crude fibre 10-92 Ash 6:06 Moist res ek yyimeaer ‘Arabins, &e. 35°60 100-00 Commerce.—The Bombay market is supplied from Ceylon. Value, Rs. 20 to Rs. 30 per candy of 7 ewts. The drug is chiefly used in India as a cosmetic. Roxburgh states that Bengal is supplied from Chittagong. a CURCUMA CZESIA, Roz. ~Hab.—Bengal. Often cultivated. The tubers. “Vernacular. —Nar-kachéra, Kali-haldi (Hind., Guz.), Kali- _halad (Mar.), Kéli-halad, Nilkanth (Beng. ), Ména-pasupu P {7el.). History, Uses, &c.—This drug is one of the two Zerumbids of modern Persian writers on Materia Medica. Strange to say, it is not noticed by most European writers on : Endinn. drugs, though it is well known and to be found in all the shops. It is the Zommon itam of Rumphius, and the Oarcuma long. of Guibourt, who classes it with the turmerics. ee Hist. Nat., I1., p. 210, 6™° Ed., where a figure will be found. Guibourt’s description is as follows :—‘‘ Ce curcuma : est en tubercules cylindriques, c’est-d-dire qu’il conserve sensiblement le méme diamétre dans toute sa longueur, malgré ses différentes sinuosités. Il est plus long que le précédent, mais beaucoup plus mince, n’étant jamais gros comme le petit -doigt ; sa surface est grise, souvent un peu verditre, rarement jaune, chagrinée, ou plus souvent nette et unie. II] est a Vintérieur d’une couleur si foncée qu'il en parait rouge-brun, ou méme noir. Il a une odeur aromatique tres dévelopée, analogue a celle du gingembre; sa saveur est également trés aromatique et cependanut assez douce et nullement amére. I] est impossible de méconnaitre dans cette racine les articles -digités du Curcuma domestica minor. Enfin, on trouve dans le eurcuma du commerce, mais en petit quantité, des tubercules 404 SCITAMINE AS, ronds de la grosseur d’une ayeline, souvent didymes, ou offrat les restes de deux stipes foliacés, Ces tubercules offrent d’ailleurs tous les caractéres des précédents, et sont les matrices radicis du Cureuma domestica minor.’ Nar-kachira appears to have been once imported into Liverpool under the name on Kutchoo. (Phar. Jour. (I1.), Vol. 1., p.17.) Aitchison (Votes on Prod. of W. Afghanistan and N. E. Persia, p. 51) remarks:— “ Zedoary, jidwar, jizwar, kachur, kachul, is imported in quantity from India, most of it to be passed on to Turkistan. The long tubers are called nar-kachul, and the round ones mada-kachul, as if they were the products of two different plants, but I have only seen them mixed together, and not sold as two distinct roots. The Turkomans employ these roots as a rubefacient, to rub their bodies down’ with after taking a Turkish bath. In this part of the country, in lieu of these, the nodes on the roots of Eremostachys labiosa and another species are collected and sent on to Turkistan. Curcuma roots are employed a little - in native medicine, and as a condiment.” The plant is a native of Bengal, and is cultivated there to supply the Indian market. Nar-kachtira is considered to have nearly the same medicinal properties as Kachira ; it is chiefly used as a cosmetic. The author of the Makhzan describes it as a kind of Zerumbaéd. (See Makhzan, article “* Zerumbéd.”) Through the kindness of Surgeon-Major Peters we have been supplied with living tubers of this Curcuma from Dinapore ; he informs us that it is common in gardens in Bengal, and is used as a domestic remedy in the fresh state much as turmeric is in this part of India, The fresh tubers are of a pale yellow colour, but after boiling and drying we find that they assume the couleur foneée of the drug found in the shops. _ Description and Microscopic structure.—-The on : minute structure of this tuber hardly differs from that of the oe ‘starch contained in the cells of the parenchyme = has been altered chy Beek and appears as a finely granular mass y filling he cell _ The resin cells are about as numerous the contents are of a dusky orange -scalariform and spiral - SCITAMINE. | 405 els. As to the drug, it consists of small nearly globular tral tubers, from which spring numerous lateral rhizomes ut the size of ginger. It is of a dark-grey colour externally marked with circular rings. Internally it is very hard d horny; of a greyish black, but when cut in thin slices of a hh-orange. ‘The odour and taste are camphoraceous. ical composition.—A proximate analysis of this curcuma Essential oil, resin, &e. 4:47 Resins, sugar, &c. 1°21 Gum, organic acids, &e. 10°10 Starch 18°75 BPA TOTO carrot se ssnvesdacasivaet ies Ay. slash ow 25°20 Ash EOC Moisture ... 9:76 Albuminoids, &e. 22°94 : 100-00 ommerce.—The drug comes overland from Bengal. Value, 4 s. 5 per maund of s. Guibourt appears to have e acquainted with it ‘Gis its admixture with the turmeric ss ata is Rosc. Scit. t. 99, a native is the Am-haldi or Am-ada (mango singer) of the of 5 ginger, and of a pale yellow colour, have an agreeable r like the rind of the mango fruit. They are much used in al as an ingredient in chutneys, and are considered to be minative, stomachic, and cooling. In their medicinal pro- ies they resemble ginger. The plant is hardly known in estern India, and is not the Amba-halad or mango turmeric Bombay, which is Curcuma aromatica. INDIAN ARROWROOT. Indian or Curcuma Arrowroot is obtained from the following plants :— ae Curcuma angustifolia, Roxb., a native of the tropical Hima= 2 and Oudh. India. The lateral tubers, which are of the size and © ea 406 SCITAMIN EAL, Curcuma leucorhiza, Roxb., a native of Behar. (Rose, Scit., t, 102 Curcuma montana, Rosc., a native of the Concan and Circars. (Roxb. Cor. Pi., t. 151.) Curcuma longa, Linn. The Turmeric plant. (Bentl. & Trim., t. 269.) Curcuma aromatica, Salisb., a native of the plains of India. (Rose. Scit., t. 103.) Curcuma rubescens, Roxb., a native of Bengal. Hitchenia caulina, Baker, a native of the Concan. (Journ. Bomb. Nat. Hist. Soc., I1., 140.) Vernacular.—Tikhur (Hind., Beng.), Tavakhir (Mar.). History, Uses, &c.—Tavakshiri, and Tavakshiryeka- pattrika are Sanskrit names for certain species of Curcuma, from which are derived the vernacular terms Tavakhir and Tikhur, now in common use for Curcuma starch. The starch is prepared in many parts of India by grating or pounding the tubers, mixing the pulp thus obtained with water, straining it through a cloth, and allowing the liquid to stand until the starch separates. This, after several washings in water, is dried in the sun, and after powdering is ready for use. The following account of the experimental cultivation of C. angustifolia and of the preparation of its starch at the Saida- pet Experimental Farm, Madras, gives the most exact inform- ation we possess regarding the yield and cost of Cureuma Arrow- root :—‘ A flat measuring 0°25 acre was planted with this crop at the end of 1879, and remained down during the year under report. It was taken up at the end of January 1881 and yielded 986 lbs. of tubers, or at the rate of 3,944 lbs. per acre. The yield of flour obtained has generally been about 124 Ibs. from 100 lbs. of tubers, so that the above yield would represent a - an outturn of 493 lbs. of flour per acre. In another case in the ' College Experimental Garden, a plot measuring 1,160 square _ yards, planted with this crop yielded 1,793 lbs., or at the rate : of! 7,500 Ibs. ‘Per acre, The culture of the plant is very simple : : Sia hecessary to plant oe eames prepared soil, SCITAMINEZ, | 4u7 and to water them occasionally during the dry season. The removal of the crop is tedious unless the tubers can be ploughed out, as potatoes are in England, which is seldom possible, owing to the dryness of the soil. The flour can be sold profitably at four annas per pound, and at this rate Rs. 400 per acre could be realized.” - ~Mr. Hamilton, F.C.S., to whom samples of the starch were _ submitted, reported that the mucilage yielded by a sample ~ marked “1st sort’? was nearly as good as that of Maranta arrowroot, but that the sample when soaked in cold water gave indications of the presence of slight acidity, and also contained a small proportion of soluble starch. He suggested the avoidance of unnecessary exposure to the sun, and the addition of } an ounce per gallon of caustic soda to the water used in steeping the _pulped roots. All the samples sent to him contained extraneous matters, black particles, straw, &c., introduced during the process of drying, which, it is hardly necessary to say, would render the article unsaleable in Europe. Curcuma arrowroot is inferior in colour to Maranta arrow- root ; under the microscope it may differ greatly in appearance, as the starch grains of different species of Curcuma are variable n size and shape. ~Commerce.—Madras in 1869-70 exported 3,729 ewts. of Cureuma arrowroot, valued at Rs. 14,152, In Bombay “ Mala- bar Arrowroot ” fetches from Rs. 3 to Rs. 4 per maund of 28 Ibs. CURCUMA LONGA, Linn. Fig.—Bent/, and Trim., t. 269; Rheede, Hort. Mal. xi., #11. Turmeric (Eng.), Cureuma, Souchet des Indes, Safran - des Indes (F*.). Hab.— Parasnathin Behar. Cultivated elsewhere. The tubers. Vernacular.—Haldi, Haldar, Halja (Hind.), Halad (Beng., Mar., Guz.), Manjal (Tam.), Pasapu (7Zel.), Mannal, Marinalu- ae!) Arishina (Can.). 408 SCITAMINE. History, Uses, &c.—Turmeric, appears to have come into use in India as a substitute for saffron and other yellow dyes, which were used by the ancient Arians before they invaded the country. The Arians were, as we know, great worshippers of the solar system, hence they held in special estimation those plants which yield a golden-yellow dye resembling sunlight, and attributed to them protective and auspicious properties. Turmeric, best known as Haridra in Sanskrit, has forty-six synonyms, such as Pita ‘‘ yellow,” Gauri “ brilliant,”? Varnavat ‘having colour,’ Kamala “lustful,” Nisa, Rajani, and all other words which signify “night.” The use of the latter synonyms is variously explained. A distinguished professor of Sanskrit, whom we consulted, referred us to one of the best commentators on the Amarakosa, who states that turmeric being a substance used for dyeing came to be called rajant, which etymologically means the material by which a thing 18 dyed, because the word rajani had already come to be used in the language to denote ‘‘night.’’ A well-known Bombay Vaid, to whom we put the question, replied, ‘‘ We have tradition that it is called ‘night,’ because in former times married women used daily to apply turmeric in the evening.” On further enquiry we learned that this practice is not extinct, as he sup- posed, but still prevails in Goan villages, about Asnora, and probably elsewhere. Married women in the evening, when the house-work is completed, dip their hands in turmeric water and pass them lightly over their cheeks: the mistress of the house also performs the same office for any married friend who may happen to drop in at this time, and on some pretence _ detains her until the lamps are lighted. The reason they g give _ for doing this is that the goddess Lakshmi may visit _ the house at this time. This goddess is regarded as the wife of ‘Surya, and the practice is probably a aise! of sun-worship. In ‘Hindu | ceremo este ial = is almost —_ necessary. » in which it.is used we may Wi s as prevailing i in most parts of India :— the snese ceremonies commence, five anoint t the bride with turmeric SCITAMINED. 409 end oil upon the forehead, head, breast, back, and feet, and the _ bride puts on a robe dyed with turmeric, which she wears until the day of the marriage. Turmeric and oil is sent from the house of the bride to the bridegroom, who is anointed in a similar manner, and sends back a similar present to the bride. The marriage contract is stained or spotted with turmeric. ‘During the ceremonies the sisters of the bridegroom perform -érta before him with a dish of turmeric water, and, dipping their fingers in it, touch his forehead. A portion of the wall is daubed with turmeric and dashes of kunku after the arrival of the bride in the bridegroom’s house, and before it are placed the /w/ and all the clothes and orna- ments constituting the marriage presents; the bridegroom, and after him the bride, prostrate themselves before this spot. The bridegroom ties a thread round the bride’s wrist, to which is attached a piece of turmeric and a betelnut. Towards the end of the ceremonies the bridal party play with turmeric water. dashing it over one another, A woman who performs sa¢i and married women when they die are taken to the funeral pile clothed in a robe dyed with turmeric. ~ At all times when pija, or worship of the gods, is made, turmeric is necessary. When a new séri (robe) has been purchased, two threads are ' drawn out, one of which is offered to Surya, and the other to the goddess Tulasi, and turmeric is applied to the corner as the cloth. Turmeric powder and kunku (a pigment made with turmeric and lime) is presented to women who have husbands living and to temple dancing girls, in the month of Chaitra, or apo the occasion of the Nauratra. The Akshata rice used in various ceremonies is coloured with turmeric and lime. In the Ramayan turmeric is mentioned as one of the eight Sea of the Arghya, a respectful oblation made to go II.—52 410 | SOITA MINE. and venerable men. The following are the lines as given im the Hindi version of that poem :— Dahi, darba, rochan, phal, mila, Nav tulsi dal, mangal-mula. Curdled milk, Durva grass, Yellow gall stones of the cow, Fruit, Roots, Lotus and Tulsi leaves, Turmerie. Medicinally turmeric is described in the Nighantds as hot, bitter, pungent, astringent and drying; it corroborates the humors, prevents skin diseases, is a useful application to swell- ings, boils, &c., and is given in jaundice. Asa domestic remedy it is in daily use; rubbed down with oil it is applied to any roughness of the skin, with lime to bruises, sprains, and all kinds of wounds; a decoction forms a cooling eyewash, boiled with milk and sugar it is the popular remedy fora cold, the : fumes. are inhaled by those suffering from severe coryza, cloth dyed with turmeric is used as an eye-shade, and ghi mixed with - powdered turmeric is given to relieve cough. Asa spice the powder is an ingredient in curries and sweetmeats, and is used by every native of India. The leaves are also used as a condiment, cence, with fish, which is wrapped in them and fried. _ Itis doubtful whether turmeric was known to the Greeks. ioscorides mentions an Indian root as a kind of «émepos resem- bling ginger, but having, when chewed, a yellow colour and taste. The Mahometans use turmeric medicinally i in the ras the Hindus; they also prescribe it in affections 3 jaundice on account of its yellow colour. There ; ; the best known are Urik-es-sufr “gold : i. oe dyers’ root.” The modern “stick saffron.” The editor of ye ot the use of a uncti ne i says it is SOITAMINEA. Se ek copious mucous discharge, and relieve the congestion. (Op. cif. a Cultivation.—Turmeric requires a loamy soil and abundance — of manure and water; the ground must be well worked and raised into ridges, 9 or 10 inches high and 18 to 20 broad, with - intervening trenches 9 to 10 inches broad. The sets, which consist of small portions of the root, are planted on the tops of the ridges, at about 18 inches to 2 feet apart. One acre requires about 900 such sets, and yields about 2,000 lbs. of the fresh root (Rorb.). Other authorities state the yield at from 1,900 to 2,000 lbs. Dalzell and Gibson give very much higher figures for the best garden soil in Guzerat, viz., 5,000 to 20,000 lbs. per acre. They state that the return to the culti- _-vator is equal to that obtained from sugar-cane, viz., Rs. 300 ‘per acre. The time for planting is usually about the end of He but it depends greatly upon the setting in of the rainy se “The crop may be raised in the following March or April; m left in the ground new shoots appear upon setting in of the following rains and the crop is lifted about 20 to 21 months after planting. In some parts of India it is not con- sidered good practice to lift the plants the first year. When the roots have to be scalded in boiling water or by steam- them in their own juice, and to be dried in the sun or in an it is impossible to obtain any reliable acreage returns. that of most Curcumas, consists of a central ovoid portion and several lateral elongated portions, all of a deep orange colour, from these proceed a number of radicles, at the ends of some of vhich colourless oval tubers are produced. The central and lateral rhizomes form the round and long turmeric of commerce, The former vary a good deal in size and shape; they may be pyriform, ovoid, or almost round, and are generally cut up into two or more pieces; the latter are cylindrical, tapering towariic the extremities, and often more or less bent ; both are pases transverse furrows, and bear remains of the rootlets nu Turmeric being much cultivated along with other crops Lae Description.—The rhizome of the turmeric plant, a oe 412 SCITAMINE A. leaf-buds. Turmeric is of a deep brownish-yellow colour, of firm resinous consistence, and has a peculiar aromatic odour. ‘Microscopie structure.—Sections of the fresh rhizome show the exterior to be composed of several layers of compressed brown cells. The parenchyme consists of delicate polygonal cells of a yellow colour, the majority contain starch grains which are mostly elongated, but some are pyriform or ovoid ; a smaller number of cells contain globular masses of yellow resinous matter, and a rich orange-yellow essential oil; those cells which contain much resin have little or no oil, when the resin is in small quantity there is much oil. The vascular sys- tem consists of sealariform and spiral vessels, which are most abundant near the boundary line which separates the cortical from the central portion of the rhizome. This boundary line is composed of small empty cells, having thicker walls than those of the rest of the parenchyme. Chemical composition.—Turmeric contains about 1 per cent. of an essential oil. Curcumin, the yellow-colouring matter of turmeric, has been examined by several chemists, whose experiments have led to the conclusion that its formula is either C'°H*°O® or O*°H"* O* that it melts at 172°, forms red-brown salts with alkalies, is converted by borie or sulphuric acid into rosocyanine, by reduction with zinc-dust into an oily body, by oxidation into oxalic or terephthalic acid, and by fusion with potash into protocatechuic acid. The experiments of Jackson and Menke have, however, led to results differing in many respect from those above detailed, which were probably obtained from impure preparations. ‘The Curcumin used in their experiments was prepared by treating ground turmeric root ( Bengal or Madras) with light petroleum to remove turmeric oil, and then with ether, which _ dissolves the curcumin together with a large quantity of resin; : and it was wee purified by crystallization from alcohol. The quantity of -eurcamin thus obtained was only 0:3 per cent. of the root ; the total quantity chsersentn in red root is, however, ee SCITAMIN EZ. 413 inous impurities, and some also in the oil. Curcumin thus spared crystallizes from alcohol in stout needles, appearing on scopic examination to be made up of well-formed prisms ‘square ends, or in spindle-shaped crystals often arranged ate groups. It has an orange to yellow colour, according eof the crystals, with a beautiful blue reflex; its solution ibits a strong green fluorescence. It is inodorous ; melts at 178°, apparently with decomposition. It atly insoluble in water, somewhat soluble in cold, more ly n hot ethyl and methyl alcohols, more soluble in glacial acid, less in ether, very slightly i in benzene and carbon uide, and all but insoluble in light petroleum. Stron ric acid dissolves it with a Gne reddish purple colour, changing to black from charring; curcumin dissolves alkalies and alkaline carbonates. Its ammoniacal ives off ammonia when boiled, and deposits unaltered Baryta water converts it into a blackish-red powder, ee a red solution like that obtained with Curcumin is not affected by acid sodium curcumin gives, as the mean of several analyses, -earbon and 5°63 hydrogen, leading to the vhich requires 68°29 carbon, 5°69 hydrogen, nd this formula has been confirmed by the derivatives. For an avcount of the deriva- nin, confer. Phar. Journ., Dec. 30th, 1882. il or Turmerol, to which turmeric (and therefore der) owes its aromatic taste and smell, has been ex- m Bengal turmeric by C. L. Jackson and A. E, Menke nt petroleum, and after being freed from the higher- rtion of that solvent by heating to 150° in a flask, ickish oily yellow liquid having a pleasant aro- it was purified by fractional datiliticn under sure, and was thereby separated into three first boiling below 193°, the second at 193° to and the third consisting of a viscous semi-solid residue. e portion consisted of nearly pure turmerol ; the first ibstance contaminated with hydrocarbons from the 414 : SCITAMINE. petroleum. The middle fraction, after further purification by distillation in a vacuum, gave, as a mean result of several analyses, 83°62 per cent. carbon and 10:42 hydrogen, agreeing nearly with. the formula C'® H’* O, which requires 83-8] C, and 10:29 H. Turmerol is a pale yellow oil having a pleasant aromatic smell, and a density of 0-9016 at 17°. It is optically Geetreuyrate, [a]=83°52. Under ordinary pressure it boils at 285° to 296°, but decomposes at the same time, yielding. a sub-. stance of lower boiling point. (Amer. Chem. Journ,, TV., pp. 805- 374.) Schimmel and Co. (Bericht, Oct. 1890) state that during a scientific investigation of Curcuma oil they proved it to contain Phellandrene. Commerce.—The bulk of the turmeric cultivated in India is consumed in the Hast as adye and condiment, and the con- sumption must be very large as every one uses it. Full parti- culars cannot be learned, but a trans-frontier trade exists, and _ the various Indian ports exchanged in 1886-87, 281,117 ewts., = : 5a hla slats Se ER ee eee ay eae ee ee ES JX tener: tess Spee me ey eke oe valued at Rs. 24,38,260. During 5 years from 1884 to 1888 Tuticorin exported 6,802 cwts. of turmeric at the average valuation of Rs. 7-8 per ewt. In the foreign trade turmeric is _ treated asa dye, and the statistics include the wild or Cochin kind. In 1885-86 the exports were 156,287 ewts., valued at Rs. 14,00,000; in 1886-87, 140,994, ewts. were exported, valued at Rs. 10,32,025. The trade fluctuates greatly: in 1881-82 only 70,783 cwts. were exported ; in 1876-77, 123,824 ewts. KAMPFERIA GALANGA, Linn. .—Rose. Scit., t. 92; Wight Ic., t. 899; Rheede, Hort. : ra-miila ({ind.), Chandt-mila, rsicals al., Tam. ), Chandra-méla, Utnen 1 SCITAMINE A. . ATR ja-nirghanta. It is much cultivated in gardens by the Hindus, whose women use the aromatic leaves and roots as a — perfume when washing their hair; on this account the yernacular names Utnen and Kapurtachit have been given to it in Western India, as its odour exactly resembles that of the root of Hedychiwm spicatum, which is sold in the bazars as a Kapur-kachri, and is an ingredient in the Utnen or perfumed powder for the hair, which has been described in Vol. ii. » p. 234. _ Rheede states that the tubers reduced to powder and mixed with honey are given in coughs and pectoral affections, boiled in oil they are applied externally to remove obstructions in the nasal passages. In the Dict. Hceon. Prod. of India(1V, 561), it is stated on the authority of Mason that the roots are often seen attached to the necklaces of Karen women, for the sake of their _ perfume, and that they also place them in their clothes for the “same reason. They are also said to be used as a masticatory ng with betel leaves and areca nut. Description.—The roots consist of branched tubers, resembling ginger in a which give off fleshy fibres bearing vhi BS seincous odour, ees like that of the Kapur-kachri of bazars. The leaves are radical, petioled, ovate-cordate, between acute and obtuse ; margins membranaceous and waved; ‘upper surface smooth, aeds green; under surface pale and somewhat woolly. The leaves are much crowded, but when they — can find room they spread flat on-the surface of the earth, the petioles are hid beneath the soil and form eylindric sheaths enclosing the fascicles of flowers, which are of a pellucid white, or iin marked with purple spots, and have the same fragrant odour as the leaves and roots. All parts of the plant have a bitterish and camphoraceous taste. The roots are not met with in commerce, but, judging from some which we have sliced and dried, would appear to be capable of supplying an article equal to the Kapur-kachri of the shops. ' (See Hedychium spicatum). The plant is culiseated with the greatest ease, and yields a large crop of roots, es ~~ sberous roots 416 SCITAMINEA, Chemical composition.—The fatty matters dissolved out of this tuber by ether consisted of a fragrant liquid oil, and a solid white crystalline substance separated by petroleum ether. The alcoholic extract, amounting to 2°76 per cent., contained some white transparent prisms of an alkaline nitrate, and a few nodules of a circular-shaped crystals of a yellowish colour. This extract contained a small quantity or alkaloid, and some sweet body reducing Fehling’s solution. A large quantity of starch is present, and 4:14 per cent. of gum. The tubers dried at 100°C lost 4:11 per cent. of moisture, and yielded 18°73 per cent. of mineral matter. KA MPFERIA ROTUN DA, Linn. Fig.—Rosc. Scit., t. 97; Bot. ae t. 920 and 6054 ; High Ic., t. 2029; Rheede, Hort. Mal. xi., Hab.—Throughout India, often cultivated. Vernacular.—Bhume-champa (Hind.), Bhin-champa (Beng.), Bhin-champo (@uz.), Bhin-chapha (Mar.), Konda-kalava (Te/.), | Malan-kua (Ma/.) History, Uses, &c.—This plant, called in Sanskrit Bhumi-champaka, ‘‘ ground champaka,” from the sweetness of its flowers resembling that of the champaka (Michelia), though not mentioned in the Raja-nirghanta, is one of the commonest domestic remedies of the Hindus. Its small globular pendu- lous tubers, at one time supposed to be the “ round zedoary ” of the druggists, are used throughout India as a local application to tumours, wounds, and swellings of all kinds. Rheede states that in Malabar the whole plant, when reduced to powder, and ‘used in the form of an ointment, is considered to be of wonder- ful efficacy in healing fresh wounds, and that, taken internally, it is thought to remove any coagulated blood or purulent matter _ that may be within the body; he adds that the root isa useful application to anasarcous swellings. In Western India the parts heii act local application in mumps* (Ga/- roots were used by the ancients for the same purpose. Cf. ei SCITAMIN EA. 417 gand), but as they are generally combined with more active remedies, such as Creton seeds, Aconite, and Nux Vomica, it is probable that they do not contribute much to the cure. The which proceed numerous, thick, fleshy rootlets, all of which, terminate in small, oblong, or round tubers; the substance of the rhizomes and tubers is of a pale straw colour, and has a bitter, pungent, camphoraceous taste, much like that of true zedoary ; the whole plant is aromatic. HEDYCHIUM SPICATUM, Ham. Fig.— Bot. Mag., t. 2300. Hab.—China Himalaya. The tubers. -~ Vernacular.—Ka4ptr-kachri, Kachir-kacha, Kachri (Hind.), _ Kapiir-kachari (Mar., Guz.), Shimai-kichilik-kizhangu (Zam.). History, Uses, &c.—Sati, the Sanskrit name for Cur-. -euma Zedoaria, is sometimes erroneously applied to this plant, ich is not mentioned in the Raja Nirghanta. In the Hima- ~ layas it is known as Sheduri, and the leaves are made into mats _ which are used as sleeping mats by the hill people. The aromatic -root-stocks are used as a perfume along with Henna (Lawsonia alba) in preparing the cloth known in the North-West Provin- ces as Malagiri (Watt). The sliced and dried root is an article of considerable importance in Indian trade, as itis a principal - ingredient i in the three kinds of Abi, or scented powder, used by the Hindus in worship, and as a perfume. White Abir is made from the following ingredients: —The root of Andropogon murica- tus, the tubers of Hedychium spicatum, sandalwood and arrowroot ndian), or flour of Sorghum. The kind of Abir called Ghisi in Hind{, and Padi in Guzerdth{, contains in addition to the _ above ingredients the seeds of Prunus Mahalib, Artemisia Siever- siana, the wood of Cedrus Deodara, the tuber of Curcuma Zedo- aria, cloves and cardamoms. Black Abir, or Bukka of the Dec- can, contains in addition to all the above ingredients, Aloes- wood, costus, the root of Nardostachys Jatamansi, and liquid Storax. The scented powder of the Jains called Vasakhepa or Ill.—53 418 SCITAMINEZ. Vasakshepa, does not contain it, but consists of sandalwood, saffron, musk, and Borneo camphor. Two kinds of Kapir- kachri are found in the Bombay market, viz., Chinese and Indian ; the latter was supposed by Royle to be the Sittarittee or lesser Galangal of Ainslie (Mat. Ind. I., p. 140), but Moidin Sheriff states that the Sittarittee of the Tamils is the true lesser Galangal, which statement appears to be correct. Powell informs us that the rhizome is pounded with tobacco and smoked in the Punjab. Description.—Indian K4ptir-kachri occurs in slices, mostly circular, but sometimes the section is made in a sloping direction ; the slices are $ an inch or less in diameter, and vary much in thickness; they are white and starchy, and when freshly pared exhibit a faint line dividing the cortical from the - central portion; the edges of each slice are covered by a rough reddish-brown bark marked with numerous scars and circular rings; here and there rootlets remain attached ; the odour is like that of orris root, but more powerful and strongly cam- phoraceous ; the taste pungent, bitter, and aromatic. The Chinese drug is a little larger than the Indian, whiter, and less pungent; the bark is smoother and of a lighter colour. Microscopie structure.—The rhizome consists of a delicate parenchyma, most of the cells of which are loaded with large ovoid starch grains, a few contain a yellowish resin, and essen- tial oil ; the epidermis is composed of several rows of compress- ed, nearly empty, reddish-brown cells. From the unaltered condition of the starch it appears that the rhizomes are not exposed to heat. ; Chemical composition.—The dried tubers have been examined by J. ©. Thresh (Pharm. Journ. [3] XV, 361). The proximate analysis gave the following results :— geen ots os petroleum ether— ethylparacoumarate............. 3° Fixed Si vad odors MON ONY Autiiesnscis <2 aos Soluble i in aleohol— ‘ “ Prt. by —— 7 : FEO eee er ers ee. 5°9 SCITAMINEA. 419 Soluble in water— Glucoside or saccharine matter 1:0 Mucila ge 2:8 Albuminoids, organic acid, &c..... weet e es Starch §2°3 Moisture 13°6 4:6 Cellulose, &e. 15:2 100°0 The odorous principle was entirely taken up by petroleum ether, upon allowing the petroleum ether to evaporate slowly,an abundant crop of large, colourless, tabular crystals was obtained, - together with a pale yellowish-brown oily fluid, These crystals, after washing with cold petroleum, were submitted to a series of recrystallizations in order to remove traces of the odorous matter. They were finally obtained quite odourless, and found _ to possess the following properties:—Soluble in petroleum BE ether, ether, alcohol, chloroform and benzol. Insoluble in diluted solutions of potash, soda or ammonia. Sulphuric acid dissolved it in the cold without production of colour, but if heated the solution became purple red. The alcoholic solution was neutral in reaction, not coloured by ferric chloride or precipitated by basic lead acetate. It did not reduce silver salts. : The melting point (uncorrected) was found to be 120—121° F, (49° C.), and after melting it would remain fluid at ordinary temperatures for days if left undisturbed. By burning with copper —— in a current of oxygen the following results were obtaine ‘2931 gram yielded *7490 ain n 00? and 1804 gram H? O. *2703 gram gave °6912 gram CO* and *1690 gram H?0O. These results agree with the empirical formula C’*H**O*°:— Ph 8 ee LE Se nT pak ele The uncrystallizable portion of the petroleum ether residue was found to consist of the odorous principle, a fixed oil and a very considerable proportion of ethylmethylparacoumarate, the latter doubtless prevented from crystallizing by the presence - 420 SCITAMINE Z. of the former. Upon saponification of the mixture with aleo-. holie potash, two crystalline acids were obtained, the methy/- paracoumaric and another, apparently a fatty acid. This latter was totally. insoluble.in boiling water, but erystallizable from alechol. The quantity obtained did not enable the author te identify it with certainty. A minute quantity of the oily fluid abovementioned dropped upon the clothes, rendered them — highly odorous for a considerable length of time, or, if exposed caused a large room to be pervaded with an odour be s that of i vactatie Commerce.—The Chinese drug which forms by far the greater . proportion of the commercial article is shipped to Indian ports via Singapore, and is valued at Rs. 44 per maund of 374 Ibs. Sir E. Buck (Dyes and Tans of the N.-W. Provinces) gives the export from Kumaon in 1875-7€ as 954 ewts., and also states that in the same year an equal quantity was exported from Garhwal, and 40} cwts. from the Bijnor district. In Davie Trade Report 25 maunds (about 2,000 Ibs.) are given as th annual export vid Peshawar to Afghanistan (Dict. Econ Prod. Ind. TV., p. 208). The Indian kind is valued in Bomba at about Rs. & per maund of 374 Ibs. It. is not so handsom¢ in appearance as the Chinese, but is more odorous. ZINGIBER OFFICINALE, ‘Rose. Fig.—Bentl. and Trim., t. 270; Rose. Monand. P., 83 ; Woodville, t. 250; Steph. and Ch., t. 96. oe Hab — Cultivated throughout the East. The rhizome. pd Ra boion adi, pat din Sonth (Hind.) ; Bea SCITAMINBA. ‘421 _ -hames, such as Mahaushadha ‘ cont remedy,” Visva “ perva- der,’ Visva-bheshaja ‘ panacea,” Sringavera “ antlered,” Katu-. badra “the good acrid,’ &e. When dried it is known as _ Sunthi and Niagara in distinction from Ardraka “ fresh ginger.’ In the Nighantais it is described as acrid and digestive, useful for the removal of cold humors, costiveness, nausea, asthma, cough, colic, palpitation of the heart, tym- panitis, swellings, piles, &c. Ginger is one of the three acrids (trikatu) of the Hindu physicians, the other two being black _ pepper and long pepper; combined with other spices and ‘sugar, as in the preparations known as Samasarkara churna and Saubhagya sunthi, it is given in dyspepsia and loss of appetite. In rheumatism preparations of ginger and other spices with butter are given internally, and it is an ingredient in oils used for external application. ‘The juice of the fresh tubers, with or : without the juice of garlic, mixed with honey, is a favourite — domestic remedy for cough and asthma, with lime juice it is used in bilious dyspepsia, and a paste of dry ginger and warm _ water is applied to the forehead to relieve headache. In Western “India, ginger juice, with a little honey and a pinch of burnt peacock’s feathers, is the popular remedy for vomiting. In old Persian we find the names Shingabir or Shangabir and _ Adrak applied to ginger, and it was probably through the Persians that the Greeks first became acquainted with it, as their (cyyiBepe is evidently derived from the Sanskrit Sringavera . Zanjabil is of similar origin, the chief difference being the | : ibstitution of the letter 5 for G, which is not in the Arabian _ Ginger is described by Piosurides as hot, digestive, gently laxative, stomachic and having all the properties of pepper ; it was an ingredient in collyria and antidotes to poison. Pliny notices it in his chapter on peppers, but very briefly, and it does not appear to have been regarded as an article of much importance in his time. In the second century of our era, ginger is mentioned as liable ito duty (vectigal) at-Alexandria along with other Indian’ through the Persian form of the word. The Arabic name 422 | SOCITAMINEA. (Vincent Com. and Nav. of the Ancients, III, 695). Galen recom- mends it in paralysis and all complaints arising from cold hu- mors; Paulusin neuralgiaand gout. Ibn Sina and other Arabian and Boisish physicians closely follow the Greeks, but enlarge upon its aphrodisiacal properties. In modern medicine the value of ginger as a carminative in atonic dyspepsia and flatulent colic, and asa masticatory in relaxed conditions of the throat is generally admitted. The manufacture of ginger beer and ginger ale forms a large portion of the mineral water trade in England); indeed, some makers have acquired a special reputation for their production. Besides the large number of fermented and aérated ginger beers consumed at home, a good deal of ginger ale is shipped in glass bottles from Belfast, especially to the United States. About 16,000 packages or casks are so exported annually, for it has become a fashionable beverage in America among all classes. According to the American official returns the imports in the : two years ending June were as follows (the duty being 20 — per cent.):— 1888. 1889. Dozen bottles. Dozen bottles. © Ginger ale and_ beer 231,721 261, 828 Ginger cordial 262 Preserved ginger (385 per cent. duty) value...... $14,289 $2,6 Hundredweights. Reel Raw ginger(duty free) 34,194 27,718 The value of the ginger ale and beer imported there was in 1887, $153,376 ; in 1888, $126,987, and in 1889, $92,001. Manufacture of ginger ale seems to have been com- menced there also ; for last year 3,512 dozen quarts were sent away from New York and New Orleans, besides what was “Tocally consumed. The teeter at ome to which h ginger is applied besides as a pA a ee ne SCITAMINE:. 423 ginger champagne, ginger cordial, as essence, —_ zenges and ginger wine. On the Continent of eis ginger is less used and appre- ciated than in Englan - Soluble essences of ginger are required for making good ; ginger beer, and Belfast and American ginger ales, There are aérated and fermented ginger beers; the best unbleached Jamaica ginger, well bruised, being deed for the latter. Ginger is also used for a kind of cordial and champagne. Lastly, young ginger is candied and preserved to a con- ‘siderable extent in the East, and comes into commerce under the section of “succades.” The quantity imported into England from India and China ranges from 300,000 to 600,000 pounds, of the value of £11,000 to £25,000. The mode of preserving it isto steep the rhizomes in vats of water for several days, hanging the water once. When taken out itis spread on ables and well pricked or pierced with bodkins. The rhizomes and nightsina vat witha mixture of water and rice flour. After this they are washed with a solution of lime, then boiled ith an equal weight of sugar and a little white of egg is added to clarify. After the ginger has been boiled a i time it is put in glazed jars of pottery, holding 1 pound, 3 pounds or 6 pounds, and covered with syrup. The syrup is changed two or three times, and then they are shipped in cases holding six jars. The quality called ‘‘ Mandarin ” is put upin barrels, (P. L. ymonds, Amer. Jn. Pharm. 1891.) - | Description.—Many qualities of ginger are met with in Eastern commerce, which vary greatly in appearance ; the fresh tubers also vary in size, flavour and colour in different soils. One variety found in gardens in the Concan has a darker colour than ordinary ginger and somewhat of a zedoary flavour ; it is known as Kala-Ala, “black ginger.” Dried ginger is knbiens in two forms, namely, the rhizome with its epidermis, in which 424 SCITAMINE A, » ease it is called coated; or deprived of epidermis, and then termed scraped or uncoated. The pieces, which are called by the spice dealers races or hands, rarely exceed 4 inches in length and have a somewhat palmate form, being made up of a series of short, laterally compressed, lobe- tee shoots or knobs. Uncoated Cochin ginger, which is the best kind produced in India, has a pale buff hue, and a striated, somewhat fibrous, surface. It breaks easily, exhibiting a short and farinaceous fracture with numerous bristle-like fibres and closely resembles Jamaica ginger in appearance and flavour. “ Black” Cochin ginger is that dried in the wet weather by means of hot ashes. Bengal and Bombay gingers have a brownish or reddish external surface, and the fractured surface is harder and darker, the flavour is less delicate than that of the Cochin sort. Coated gingers are now seldom met with, but Indian commercial samples usually contain a proportion of shrivelled and im- perfectly scraped roots, ‘ 4 ~ Ohemical composition.—Ginger has been very completely - examined by J. C. Thresh. (Pharm. Journ. (8) xii, 721). — He found Cochin ginger to contain volatile oil 1°350 ; fat, wax (?) and resin (in the petroleum ether solution), 1:205; neutral resin ‘950; a. and b. resins, °865; Gingerol, *600 ; substance precipitated by acids, 5°350; mucilage, 1450; indifferem® | substance precipitated -by eas, organic acids, &c., 6°8 a extractive soluble in alcohol not in ether or water, *280; alkalotd a trace; metarabin, 8-120; starch, 15-790 ; pararabin, 14°400; oxalic acid (as CaC*0*), +427; cellulose, 3-750; albuminoids, 5°570; vasculose, &c., 14763; moisture, 13°530; ash, 4°800. The essential oil is pale- yellow, levogyre and not acrid. S28 Gingerol, the active principle, is a straw-coloured, viscid, © | odourless fluid of extremely pungent taste. : cording to S. J. Riegel, East India ginger yields 8 per conk. ei oleo-resin, whereas Jamaica ginger only yields 5 per cent. fee be be best extracted by alcohol, ether or chloroform, - benzin will dissolve it, but it d ee exhaust the Fs oe SOITAMINER. 425 __ Commerce.—Ginger is extensively cultivated in British India, _ from the Himalayas to Cape Comorin. In the Himalayas it is successfully reared at elevations of 4,000 or 5,000 feet, requiring, however, a moist soil. The Malabar ginger, exported: from Calicut, is the produce of the district of Shernaad, situated to the south of Calicut. In the Dacca district the natives cleanse the roots in boiling lime water, which probably injures much of the fragrant pungency, whereas in Jamaica they use simply plain water. In order to dry ginger into what is called “sonth” in India —that is, to enable it to keep—the fresh roots are put into a basket, which is suspended by a rope, and then two men, one ‘on each side, pull it to and fro between them by a cord attached, and thus shake the roots in the basket ; this process is carried on for two hours every day for three days. After this the roots are dried in the sun for eight days, and again shaken in the basket ; the object of the shaking being to take ff the outer scales and skin of the roots, Two days further ‘drying completes the process, and the ginger sells at about a rupee, or two, for 6 or 8 pounds. The value of the East Indian ginger exported went on increasing from about £63,000 (44,457 hundredweights) in 1881 to over £199,000 (133,280 hundred- weights) in 1887; but in the last three years it has retrograded, having fallen to £70,398 (61,774 hundredweights) in the financial year ending March, 1890. Last year, of 63,500 ewts. imported into England, India sent 53,500 ewts., Jamaica, 5,900 cwts., and West Africa, 2,600 s. (P. L. Simmonds.) ZINGIBER CASSUMUNAR, Rozh. Fig.—Rozb. in As. Research. 31, t. 7; Bot. Mag., t, 1426; Box. Monand. Pi. Hab.—lIndia. The rhizomes. LII, —54 426 SCITAMINE, Vernacular.—-Ban-ada (Beng.), Nisa, Malabari-halad (Mar.), Karpushpu (Tel.), Ban-adrak, Ban-adi (Hind.). History, Uses, &c.—This plant, in Sanskrit Vadrn- draka or “wild ginger,” though not mentioned in the Raja Nirghanta, appears to be well known in most parts of India as a domestic remedy among the peasantry, who rub down the tubers with water for administration in diarrhea and colic. Though Roxburgh has named this plant Cassumunar, it appears to be very doubtful whether its roots have ever been exported to Europe or have ever been an article of commerce in India. Kattu-mannal is a Malabar name for the yellow zedoary, and it appears to be this plant which has furnished the Cassumunar root of the druggists (cf. Pereira, Mat. Med., ii., Pt. 1, p. 236). Inodour and taste both roots are very — niiniiet. The Marathi name Nisa is Sanskrit and signifies ‘‘turmeric,”” and seems to indicate that the tubers of this plant are used as a substitute for that article by the peasantry. Description.— The fresh rhizomes are 1 to 2 inches in diameter, jointed, compressed, with numerous white fleshy radicles, to some of which white tubers are attached. Each joint of the rhizome is furnished with a leaf bud. The epidermis is scaly, light-brown, the interior of a rich golden yellow, the odour is powerful and not very pleasant, like a mixture of ginger, camphor, and turmeric; the taste hot and camphoraceous. _ Microscopic structure.— The epidermis is formed of many ers of compressed and obliterated cells. The parenchyma consists of large polyhedral cells; those in the cortical portion of the rhizome are nearly free from starch, but those in the central portion are filled with large ovoid starch granules. all parts of the rhizome large cells full of a golden-yellow essential oil abound. nie eerie Senet resembles that — of — ea. SCITAMINE, , 427 Chemical composition.—The drug yielded to analysis :— Ether extract (essential oil, fat, and soft resins) ... 6°96 Alcoholic extract (sugar, resins) ; 0:29 Water extract (gum, acids, &c.) 13°42 Starch 15°08 Crude fibre 12°61 6 6°80 RRO ERS 0 : Albunaincias modifications of arabin, &eo. ro nee 30°18 100-00 00. pene root had a pungent odour, similar to a mixture of cam- We were doable to separate any of the “soapy extrac- ive” mentioned in the analysis of Cassumunar root by Luca. Costus speciosus, Sm., Lam. Ill. i., t. 3; Rheede, Hort. Mal. xi., t. 8 - Vernacular.—Kei (Hind. and Beng.), Penva Tar (Mar.), -Kemuka (Sans.). Roxburgh notices a preserve made of the fresh roots which is considered wholesome and nutritious. speciosus is the Tyana-kua of Rheede and the Herba spirals hirsuta of Rumphius. Ainslie, quoting Brown’s History of Jamaica, says that the root is there used as a substitute for ager, but is very inferior to it. (Ma#. Ind. ii.,167.) In the ta Exhibition Catalogue, the root is Saiwhod as depura - tive and aphrodisiac; similar properties are attributed to it in the Concan, where it is very abundant in moist situations. The rhizome resembles the great Galangal in growth and structure, but has no aromatic properties, the taste being mucilaginous and feebly astringent; it could only be used as a substitute for | : ginger by being preserved with a quantity of that root suffi- t to flavour it. 428 - SOITAMINEZ. sd ELETTARIA CARDAMOMUM, maton. Fig.—Rheede, Hort. Mal. xi., tt.4 and 5; Bentl. and Trim., t. 267 ; Woodville, ¢. 231; Roxb. Cor. Pl. iit., ¢. 226. Malabar Cardamom (£ng.), Cardamome du Malabar (F’.). Hab.—West and South India. The fruit. Vernacular.—Chhoti-iléyachi or ildchi (Hind.), Elaich, Gujrati-elaich (Beng.), Elchi (Guz.), Veldoda (Mar.), Ella-kai (Tam.), Yalakki (Can.), Elettari (Ia/.), Elakaya, Vittula ( Ze/.). History, Uses, &c.—The small cardamom, in Sanskrit Ela, is mentioned by Susruta. In the Nighantas it bears various synonyms, such as Truti, Kapota-varni “grey,” Korangi, and Dravidi ‘‘ coming from the Dravidian country.” The large or Nepal cardamom (Amomum subudatum) is called Sthulaila “large Ela,” and is described separately. Both kinds are considered to be digestive, pungent, light and hot, and are recommended in phlegmatic affections, such as cough, asthma, piles, and diseases of the bladder and kidneys. These two eardamoms are described by Ibn Sina under the name of ~34 (kakulah); he also describes separately under the name of ty2U4, (hilbawa) another kind of cardamom as ‘more easily digested than the kakul/ah. This latter cardamom is the true Cardamomum majus or Nutmeg cardamom of Africa to which Pereira has given the name of Amomum korarima. We think that there can be no doubt that the Greeks were acquainted with the cardamoms of India which they appear to have first obtained from the Persians through Syria and Armenia. Dioscorides says : :—“ Choose that which is tough, well filled, closed; if not in this state, it is too old and has lost its aroma. The taste is pungent and somewhat bitter.” With respect to the name Katidéis, the Greeks appear to have applied it to this spice in much the same way as the Persians applied the name kakulah, which originally meant the fruit of some other _ plant which was used for flavouring bread. In the Burhan it oa is stated that the name kakulah is also given by some to a fruit ee like sapandan . Eads! ae which is the same as Ilachi. NE De ENE es Bees ee 1 ee a a ne to Si cua alee ees SOITAMINE A. 429 Besides the two Indian cardamoms, there isa large kind of cardamom which comes from Ceylon, now found in commerce. Dr. Trimen, in his Systematic Catalogue of the Flowering Plants and Ferns of Ceylon, speaks of the plant which produces it as Elettaria cardamomum, Maton, var. major—the Ensal of the Singhalese. As a masticatory and for flavouring food, the Malabar or small cardamom is preferred by the natives, but the other kinds, which are cheaper and of less delicate flavour, are largely used by the sweetmeat makers. Cultivation.—There are two ways of propagating the plant, viz., by sets or by seed. The chief requirements for successful cultivation are a rich loamy soil, and a site sheltered from strong winds and too much direct sunlight. Clearings in forest land, with a few trees left here and there, in order to give the requisite shade and shelter, are found to offer the best conditions for the production of good crops. In the planting of sets, young ones of one to two years old should be chosen. Holes one foot deep and 18 inches wide are dug, and into these, after they have been prepared as beds, raised a few: inches above the surrounding ground, the sets are inserted just below the surface of the soil. The spaces between each plant may be from 6 to 12 feet, according to the quality of the soil. The ground should be well cleared of weeds, stones and rubbish, but when the plants have grown to a certain size, no further weeding will be necessary, as nothing will grow under their shade. Seeds should be sown in prepared nurseries, care being taken not to sow too deep. e seedlings, when 6 to 8 inches in height, should be transplanted and treated in the same manner as sets. (Dict. Econ. Prod. Ina. iii, p. 229). For the particulars of cardamom cultivation in the Wynaad, Travancore, Mysore, Madura, Coorg, and Canara, the same work may be consulted. To prepare cardamoms for the market, they are washed, bleached, and starched. For washing, 2 lbs. of pounded 3 soapnuts and } lb, of Acacia concinna pods aremixed with about = 430 SCITAMINEZ. 5 gallons of water, and a separate solution of common country soap ismade. Three quarts of the soapnut mixture are added to 8 quarts of water, and in this 10 lbs. of cardamoms are well agitated by hand and then transferred to a basket to drain for a few minutes. They are then washed a second time in 7 quarts of water, one of the soapnut mixture, and one of the soap solution, drained and thrown upon a mat. Then they are continually sprinkled with fresh water by relays of women until sunrise next morning, when they are spread out on mats to dry for four or five hours. The stalks are then cut off with scissors, at which work some women are so expert as to be able to nip 90 cardamoms in one minute. This done, the cardamoms are sorted for export. The starching process, which has only lately been introduced, consists in sprinkling the cardamoms with a thin paste made of rice and wheat flour, country soap, and butter milk, and rubbing them between the palms of the hands. The washing mixtures are used for two lots of cardamoms and are then thrown away. The women who wash are paid 3 annas per diem; the night watchers 4 annas, and the nippers 24 annas per 13 lbs, Description.—The cardamom of commerce is a dry, three-sided, oblong, or roundish capsule of a yellowish-brown or dirty white colour. The pericarp is tough, and divides into three valves, from the middle of the inner surface of each a partition projects towards the axis, so as to divide the capsule into three cells, each of which is filled with closely packed angular seeds, each surrounded by a thin transparent membrane (aril). The seeds are of a rich brown colour, about two lines _long, roel rugose, with a depressed hilum, and deeply. channelled raphé. The capsule is almost tasteless, The seeds | have a pungent, camphoraceous, agreeable flavour, and leave a — of cold upon the tongue when chewed. 08 opie structure.—The testa of the seed is formed of ayers See a os of thick-walled striated cells; 2nd, a ge d cells; 3rd, an internal layer of dark- The albumen is 2 SOITAMINEZ. 431 Beslcurless and consists of polyhedral cells containing starch, 4 and generally rbomboidal masses of albuminous matter, which 4 ean be easily seen when thin slices of the albumen in almond _ oil are examined by polarized light. . ‘ : Chemical composition.—The parenchyme of the albumen and embryo is loaded with fatty oil and essential oil, the former i The essential oil, which amounts on an average to 4°6 per cent., ‘has the odour and flavour of the seeds; it consists chiefly of a liquid having the formula C!° H?? 0%. According to Fluckiger, the raw oil is dextrogyre, and deposits after a time a camphor, which he considers to be identical with common camphor, as distilled, contains acetic acid. The ash of cardamoms, which, according to Warnecke, amounts to 6°12 per cent. in common with that of several other plants of the same order, is remark- bly rich in manganese. Commerce.—The trade in Indian cardamoms seems to have been declining for some years past. In 1880-81 the exports to foreign countries were valued at Rs. 8,20,257, but the ‘returns for that year were the highest on record. For subsequent years they were as follows: —1883-84, Rs. 5,68,334 ; 1885-86, Rs. 5,60,012; and 1887-88, Rs. 2,04,858. In : 1883- 84, the United Kingdom received of the above, cardamoms _ tothe value of Rs. 4,05,649, but last year only Rs. 52,658. After the United Kingdom the other receiving countries are : a relly in the following order of importance:— Arabia, Germany, Persia, On the other hand, the imports of foreign ¢ardamoms seem to be on the increase. In 1880-81 they were valued at Rs. 4,134, and taking the same years as have been given for the exports, the imports were in 1883-84, Rs. 18,351; 1885-86, Rs. 92,205; and 1887-88, Rs. 2,60,450. During this year the bulk of the imports (viz., Rs. 2,51,211 worth) came from Ceylon, and of the total of these foreign | soporte; Boatey received Rs. 2 sce te pera Of the inte 432 SCITAMINEZ. trade in cardamoms, full statistics are not available, but exclud- ing the transfrontier trade by land, it was last year valued at Rs. 25,11,053. In Travancore the cardamom cultivation and trade are a monopoly of the State. The drug is grown on the Cardamom Hills, and is brought down, under guard, to Alleppy to be ex- ported. The following table gives a Statement of the sale of Travancore cardamoms during the last sixteen years :— Statement of the Sale of Travancore Cardamoms, 1875 to 1891. Cardamoms | Average price per ; Year M. E. in A cies en ee dy in. Rupees. Total amount realized. Rs. | Rs. 1051 275 838 2,30,268 1052 47 1,600 74,692 1053 133 1,719 2,28,526 1054 140 2,353 3,28,176 1055 248 1,966 4,87,596 1056 188 1,833 3,44,320 1057 158 1,427 2,25,855 1058 62 1,825 1,138,397 1059 303 1,018 8,08,601 1060 484 769 3,72,278 1061 148 682 1,01,101 shite ROGQ 88 863 75,892 — 1063 256 492 1,26,058 1064 176 776 1,36,018 1065 — 84 590 49,787 1066 | 326 534 1,74,847 _ This table includes ludes all cardamoms sold. Some will be Lsome sent by backwater to Cochin, so SCITAMINE.. A33 that is sent to Cochin will also appear as exports from that The following notes have been kindly furnished by Mr. T. Bourdillon, Conservator of Forests, Travancore, late Superin- ent of the Cardamom Hills :— The cardamom plant is indigenous in the evergreen forest of vancore, between the elevations of 400 and 4,000 feet, but ives best at the higher of these altitudes. The spice is divided into 3 classes : (1) Magara élam, or those ) Kanni élam, those which ripen in the month of Kanni September) ; and (3) Weela élam, or long cardamoms. difference in the time of ripening is due to differences of itude and climate. he scapes on which the capsules are borne, in the ease of the two classes, always clio on the aac whereas the : Magara cas are considered the best. The plants that pro- = ce them are grown at an elevation of 3,000 ft. and upwards — nthe eastern edge of the Travancore Territory, where the nfall is comparatively light, reaching probably not more 60 inches, In this comparatively dry district the capsules pepger to mature, and though the plant flowers in March es do not ripen till January, and are considerably larger - — more seed than the other kinds. ‘ 434, SCITAMINE. Nééla élam come last. The plants are larger, and the scapes stand upright as already said. The capsules are long and less aromatic than those of the other two kinds. . This variety is found on the hills of South Travancore, where the rainfall is heavy (150—200 inches) and where the sea breezes blow. The elevation is between 1,000 and 3,000 ft. Although cardamoms are wild in the forests, they have been cultivated in gardens from time immemorial, and from old records it is seen that the oldest gardens which were in existence when Lieut. Ward made his survey of the country in 1817 are still the most productive. These gardens are found on the eastern edge of the Travancore hill-plateaux, where the Magara élam are produced, and this variety yields about } of the total produce of the country. Some gardens are met with in the Kanni élam district, but these are more modern, and the yield is about } of the total crop each year. “Long cardamoms” are not grown in gardens; they are all collected wild from the forests. When a person intends to open a garden, and has obtained permission to do so (for cardamoms are still a monopoly in Travancore), he selects some heavy forest, where there are already a few plants of cardamoms growing, carefully avoiding those places where reeds grow, as indicating poor soil. The common saying is that where the Anjili (Artocarpus hirsuta) and white cedar (Dysogylon malabaricum) grow, there carda- moms will thrive. The smaller trees and undergrowth are then cut down, only the larger trees being left to forma close canopy overhead. he garden is then kept clear of weeds by a cutting over and \ : ae Rikioe a year, and cardamom seeds are sprinkled about, _ or the rhizomes are planted out when the plants have not come -up properly, In about 3 years the garden begins to bear, and may continue to do so for upwards of a century if the light is not allowed to enter toomuch. Should any of the larger trees fall down and let the light i in, the cardamom plants turn yellow : and give a Lea A SOR but shen die out until shade has been SCITAMINES,. 435 __ Each year when the cardamoms ripen, they are collected and _ dried on rocks, and when thoroughly dried they are delivered _ to the Cardamom Superintendent, who weighs them in and 3 despatches the crop under escort to the Court, where it is sold, _ and the grower gets two-fifths of the price realised at the annual auction, the Government retaining the other three-fifths. The crop yielded per acre is not large, and, indeed, a heavy crop is a disadvantage, as it would imply that the garden was _ about to die out. Equal crops of good full capsules are to be _ desired, and as the trees above drop their leaves and manure the plants below, no further manuring is necessary, though it is generally admitted that manuring would largely increase the crops were it feasible to carry out such operations. It has been estimated that there are about 26,000 acres under -cardamoms in Travancore, and 13,000 thulams (of 20 lbs. each) a large crop. Even supposing that the area was much over- estimated, it is probable that the annual crop does not exceed _ 10 Ibs. to the acre, though we have heard it placed at double that amount. _ It will be seen by the figures quoted above that the crops of ardamoms in Travancore vary very considerably, the fact being that the setting of the blossom in March, April and May is very much dependent on the weather, frequent showers dur- ing those months bein most favourable toa good crop, while a heavy monsoon is said to destroy the young fruit. Here too, as in the case of most fruit crops, a good year is followed by one or two bad ones and vice versd. fallen to about 2 of its former level, so that the annual amount realized by the Government hardly pays for the establishment required te watch and guard the crop from being Stolen. The owners of gardens, who are chiefly villagers from the adjoining district of Madura in British India, scarcely ‘secure any return for their work, andit is now in contemplation — to abolish the monopoly altogether. . 436 SCITAMINEZ. - A considerable proportion of the cardamoms in Indian commerce consists of the seeds, without the husks, These seeds are obtained from overripe fruits which have burst in the field or during manipulation, and are of two kinds, Indian and Chinese. The latter are said to be the seeds of Amomum wanthtoides. (Hanbury, Science Papers, pp. 100, 178, 250, 291.) Amomum subulatum, Lozd., is much larger than the true cardamom, of a dark-brown colour and coarsely striated, three- valved, each valve being furnished with three ragged, membrancous wings, which extend from the upper part of the fruit and gradually disappear towards the apex. The seeds are arranged as in the true cardamom, but are more numerous, and are held together in each cell by a dark viscid saccharine pulp. Their taste is aromatic and camphoraceous. They are much used in the preparation of sweetmeats on account of their cheapness. Value, Rs. 12 per maund of 374 lbs. The Nutmeg Cardamom, or true Cardamomum majus,* made its appearance in the Bombay market in 1885. Up to that time the only large cardamoms we have met with have been the Bengal or Ceylon kinds. Under the name of Hil-bawa it is correctly described by the Arabian physicians, who no doubt were acquainted with the genuine article. . Persian and Indian writers are evidently not acquainted with it, although they copy the description given by the Arabs. The See macographia has the following account of this rare Cardamom:—“ The true Cardamomum majus is a conical fruit = in size Sai shape, not unlike a small fig reversed, containing roundish angular seeds, of an agreeable aromatic flavour, much pees that of the Malabar cardamom, and quite devoid ig taste of grains of Paradise. Each fruit is bing fs been strung on a cord to dry; such strings are. Sometimes used by the Arabs as rosaries. isc the Galla ena Korarima, SOITAMINES:. 437 but is also known as Guragi spice, and by its Arabic names of Heil and Hab-el-habashi. According to Beke, it is conveyed to _ the market of Béso (10° N. lat.), in Southern Abyssinia, from _ Tumhe, a region lying in about 9° N. lat. and 350 E. long.; thence it is carried to Massowah, on the Red Sea, and shipped for India (?) and Arabia. Von Heuglin speaks of it as brought from the Galla country. It is not improbable that it is the same fruit which Speke saw growing in 1862 at Uganda, in lat. 0°, and which he says is strung like a necklace by the Wagonda people. oak ti wae ALPINIA OFFICINARUM, Zaunee. _ Fig.—Bentl. and Trim.,t. 271. The lesser Galangal (Zng.), etit Galanga, Galanga de la Chine (I’.). ~Hab.—China. The rhizome. Vernacular.—Kulinjan, Pén-ki-jer (Hind.), Shitta-rattai Tam.), Kulinjan (Mar.), Kulanjan (G@us.), Kunjara-kathi Sind.), Sannaelumpardsh-trakum (Ze/.), Kalanjan (Can.). History, Uses, &c.—The Chinese call the Galangals aon-leang-keang and Liang-keang. From the first of these names the Arabs have derived their name Khulanjan or ~ same name occurs in the Nighanta’s, which rink it evident t the Hindus first became acquainted with Chinese galangal ugh the Arabs. The earliest notice of the drug occurs in ersian literature (cf. Bur han), where it is stated that Khusri- ré, “Chosros remedy,” was introduced in the time of oshirwan (6th century). It probably reached Persia by the Central Asian trade route, as we find that it is still used by the ‘artars to flavour their tea. Paulus gineta (7th century) ” calls it yaddyyas, and latter Greek writers xaAi¢ev, yaddSeas and Gia, Ibu Khurd4dbah (9th century), in enumerating the of a country called Sila, names galangal, and three. hundred years later, mentions it as prone - 438 SCITAMINEA. India and China to Aden. Ibu Sina and other early Arabian physicians also notice it shortly as a stomachic and stimulant. Curious stories as to its source were current in those days; Haji Zein states that in Yundn a kind of hawk is said by travellers to build its nest of the roots of the Khtilanjén upon the sea-shore, and that the only way of obtaining the drug is to rob these nests ; this the merchants do, and, after washing the roots, cut them up into short pieces. Although this drug has been so long known, its botanical source was only discovered in 1870, when a description of the plant was communicated to the Linnean Society of London by Dr. H. F. Hance, made from specimens collected by M. E. C. — Taintor near Hoihow, in the north of Hainan. (Journal of the Linn. Soc., 1873, XIII., 6.) Galangal is described by Serapion on the authority of Ishak bin Amraén as hot and dry in the third degree, useful . phlegmatic persons, and in humidity of the stomach ; promotes digestion by its heat and the solution which i occasions in the stomach, and thus relieves colic; gives fragrance to the breath, and warms the kidneys: it sets the semen in commotion, and when a piece of it is held in the mouth it occasions erections of the membrum virile. Other Arabian writers give a similar account of it. Indian Mahome- tan writers, with reference to the name Pén-kt-jar, say that the drug may be the root of very old plants of Piper Betle, but they are evidently in doubt about its being produeed by that plant. (Makhzan, article “ Khilanjan.”) Mir Muhammad Husain describes Galangal as tonie, stomachie, carminative, stimulant, and aphrodisiac. He tells us that if given to young children it makes them talk early, and that a paste of the powdered drug made with oil or water will remove freckles. It is a stomachic tonic, used by native practitioners to reduce the quantity of urine in diabetes. It is used to correct foul breath when chewed, and the juice swallowed stops irritation in the throat. (Hmerson.) Galangal is one of the ingredients of tae Ce as is not used in English medicine, but — is a. ieee ble | — where it is SCITAMINEZ. 439 used for a variety of purposes, as for flavouring the liqueur called Nastoika, it is also employed by brewers, and to impart — a pungent flavour to vinegar, a use noticed by Pomet so long . 694. As a popular medicine and spice, it is much sold ‘in Livonia, Esthonia, and in Central Russia. It is also in ‘Tequisition as a cattle medicine, and all over Europe there is a small consumption of it in regular medicine (Hanbury). Irvine (Med. Topog. of Ajmeer, p- 171) says that the natives add Kulijan to bazar spirit to make it more intoxicating. _ Description.—The dried rhizomes are about as thick as the little finger or often less. They have evidently been cut into hort lengths (2 to 3 inches) while fresh; many of the pieces re branched, and all are marked by numerous circular ridges ta light colour. The external surface of the rhizome is of a ep Sivek brown, the interior pale red, hard and tough ; the odour is aromatic and the taste hot and spicy. Microscopic structure.— The bulk of the rhizome consists of uniform parenchyma traversed by fibro-vascular bundles, e of the parenchyme cells are full of resin and essential oil, most of them contain large starch grains of an elongated or b-shaped form. : ee! composition.— Galangal contains fon 1 to 4 per nt. of anessential oil, which is the odorous principle ; according angal with ether a neutral, inodorous, tasteless, crystalline ody, Kempferide. EE. Jahns (1883) has isolated the following mp from the root: Kampherid, C'6H!?0°H°0, izing in yellowish needles (m. Pp. 221°), which are htly soluble in water, ether and benzine, freely soluble in alcohol, soluble in alkalies to an intensely yellow solution, and in concentrated sulphuric acid to a yellow solution with a strong blue fluorescence. -Galangin, C'*H! °0°H°0, crystallizing from its solution in aqueous alcohol in yellowish-white needles - p. 214°). The reactions of this body are very similar to _ hose of kampherid ; its solution in concentrated sulphuric acid, vever, is non-fluorescent. ae 44) SCITAMINE. Alpinin, C'"H'*05, crystallizes in yellowish needles (m._ : p- 173°). Its reactions are similar to those of galangin. (Archiv. der Pharm., CCXX., 161; Year-Book of Pharmacy, 1882, p. 199.) The resin, which is peobebly the acrid principle, has not been examined. Dr. Thresh (1884) has isolated from Galangal root an active pungent principle, which he has named Galango/, and which E resembles the pungent principles of Ginger, Capsicum, and grains of Paradise in certain respects. He records the follow- ing proximate analysis of 100 parts of the rhizome:— Volatile oil 0°6, resin 0°2, fat and Galangol 1:6, kampferid, &c., 14, other saline matters soluble in ether but not precipitated by Pb. A? 1-2, tannin 0°6, phlobophane 1-2, other substances soluble in alcohol 3°2, glucose, mucilage, &c., 3°5, oxalic acid 0°3, galangal red 2°8, starch 23-7, albuminoids 2-6, moisture 13°8, ash 3°8, cellulose, &c., 39°5. The active principle could not be isolated : in a state of purity. 4 Commerce.—The imports of Galangal into India average ; 3,300 cwts. yearly. In 1883-84 they amounted to 3,870 ewts., valued at Rs. 35,982, of which Calcutta took 4 686 ewts., Bombay 1,750 ewts., and Madras 1,434 cwts. Of the total imports 1,230 ewts. came from Hongkong, 2,540 ewts. q from the Straits Settlements, and 100 ewts. from other countries. During the same year 1,670 ewts. were re-exported to Arabia and Persia. Galangal is valued in Bombay at about Rs. 3} per maund of 374 lbs. _._ ALPINIA GALANGA, villd. ae F —. Amb, v., t. 63. The greater Galangal, langal (Eng.), Galanga grand, Galanga de Java (FY.). ne Hab. f bile, and is useful in leprosy, piles, colic, boils, and to expel intestinal worms. The starch obtained from the root by hing is given internally in gonorrhea. Moodeen Sheriff, who has experimented with the root, states it. is not so poisonous as is generally supposed; he has n it in small quantities, gradually increasing the dose to 15 ins. There were no bad effects, but on the contrary he ad his appetite improved and felt more active and stronger. has also used it in his practice for many years, and considers be a tonic and stomachic in doses of from 5 to 12 grains en three times a day. In the Concan it is given to cattle to yorms, and in Madras it is believed to bea specific against tes of poisonous snakes, and the stings of scorpions, and ons. Surgeon-Major Thomson states that before being for these purposes it is cut up into thin slices and soaked itter-milk and salt for four or five days, and then dried, He also says that the natives select those roots dichotomous and which they suppose to be those of plant, whilst single roots, which they suppose to be the female plant, are rejected. (Dict. Econ, Prod. iii., p. 507.) ption.—Root tuberous, cylindrical or flattened, to 8inches in length, and about one inch in diameter ; ally grown it consists of two tubers which unite at a right one being much shorter than the other; at the point of nay be seen, on the upper surface, a circular scar marking hment of the stem, and on the under surface imme- beneath it another, to which a tuft of their rootlets is ir points, which are tapering and nearly white; _ oe are -_ white, and euieacanar and have a— ‘The tubers are covered with a brown epider- a 482 LILIACEZE. faint acrid odour.- The taste is mucilaginous, feebly bitter, and has an acid taste. The starch granules are mostly ovoid, the vascular bundles few, consisting of spiral and jointed vessels. The root is figured by Lyon. (Med. Juris. for India, p. 210.) Chemical composition.—The root has been examined by War- den, who obtained from it two resins, a tannin, and a bitter principle which he has provisionally named Superbine. He considers that the bitter principle is closely allied to, if not identical with that of squills. It was found to be very poisonous, 0°047 gram injected into the stomach being sufficient to kill a full-grown cat. (Ind. Med, Gaz., Oct. 1880.) Toxicology.—Ainslie and others speak of the root as violently poisonous, and it finds a place in the list of Indian poisons published by Chevers. (Indian Ann. of Med. Sci, ii, p. 147.) © . Dr. Buttacharjee (Ind. Med. Gaz., 1872, p. 153) reports the following case :—A female, et. 18, swallowed a quantity of the powdered root. Symptoms of poisoning appeared in half an hour, and were: retching, violent vomiting, spasms and con- tortions of the body, with fearful racking pain; from time to time there were short intervals of relief, followed by a recurrence of the same symptoms. Death took place in four hours. The post-mortem appearances were congestion of the brain and its membranes, with extravasations of blood. The lungs, liver, and kidneys were all deeply congested. The gastric mucous membrane showed signs of inflammation. The peritoneal covering of the fundus of the uterus (unimpregnated) was also found inflamed. ASPARAGUS RACEMOSUS, Wild. Fig.— Wight, Tc., ¢. 1056. Hab.—Throughout India. LILIACEA. ‘ 483 ASPARAGUS SARMENTOSUS, Willd. Fig.— Rieede, Hort. Mal. z., ¢. 10. Hab.—-Upper India, Concan, and Deccan. The roots. Vernacular.—Satdwar, Satdvari (Hind., Guz., Mar.), Satamuli (Beng.), Shataévali (Mai.), Kilévari (Zam.), Shatavari (7e/.), _ Shipari (Can.). History, Uses, &c.—These two plants appear to be the Satévari and Maha-sativari of the Nighantés: among the _ synonyms of the first, we find Dvipika, Dvipa-satru, Vara- ghantika, Nirdyani, and Sata-padi; the synonyms of the second are very similar, amongst them we note Bahu-puttrika, Dagdha, and Bhasma-roha. Both plants are considered to be heavy and cold, sweet, demulcent, galactogogue, tonic, and strengthen- ing, and to remove bilious and rheumatic humors, blood diseases, and swellings ; they are used .both internally and in the pre- paration of several medicated oils. The tubers are candied and eaten as a sweetmeat. The fresh juice of the root is given with honey as a demulcent in bilious dyspepsia or diarrhosa (Sdrangadhara). Asan aphrodisiac, Chakradatta directs four sérs of the juice. of the roots and four sérs of ght to be boiled in forty sérs of milk, and to be flavoured with sugar or honey, and long pepper. The chief use of the drug, however, is in the preparation of Medicated oils for external application in nervous and rheumatic affections and urinary disorders. The Nérdyana taila, a ‘Popular remedy of this kind, contains the barks of gle Marmelos, Premna integrifolia, Oroxylum indicum, Erythrina indica, Stereospermum suaveolens, and Pederia fetida ; the roots of Withania somnifera and Boerhaavia repens, the fruit of Tribulus terrestris, and the leaves of Solanum xanthocarpum, Solanum indicum, Sida cordifolia and Sida rhombifolia, of each twenty tolas. The whole collection is boiled in 64 sérs of water down to one-fourth and strained. To the strained decoc- tion is added four sérs each of the juice of Satdvari and 484 LILIACE&. prepared sesamum oil, sixteen sés of cows’ or goats’milk, and a paste prepared with four tolas of each of the following drugs— Fennel seeds, wood of Cedrus Deodara, root of Nardostachys Jatamansi, liquid storax, Acorus root, sandalwood, herb o Limnanthemum cristatum, costus, cardamoms, leaves of Desmodium gangeticum, of Uraria lagopoides, of Phaseolus trilobus, and of Teramnus labialis, roots of Withania somnifera, Vanda Roxburghi, and Boerhaavia repens, rock salt. The whole is then reboiled and perfumed. (Chakradatta.) Description.—Both plants are scandent woody shrubs, the roots of which consist of numerous fusiform, smooth, per- ennial tubers, 6 to 8 inches long and }inchin diameter. They have a light brown, silicious external covering which is removed before they are used. The substance of the fresh tubers is mucilaginous, white, and somewhat translucent, and has a mawkish, insipid flavour. Chemical composition.—The powdered roots were separated into— Water extract 52-43 Crude fibre 33°65 Moisture 9°46 Ash 4°46 100°00 The amount of saccharine matter, estimated as glucose, in the water extract was7:14 per cent. Some of this extract was boiled and filtered and evaporated down toa soft consistence and allowed to remain for three months under a bell jar. At the end of that time no crystalline substances had formed, indicating the probable absence of crystalline sugars, mannite, and asparagin, | 508% Asparagus ad dens, Rovb., is an herbaceous, erect, thorny plant growing in Rohilkhand, Guzerat, and other parts — LILIACE. 485 f Central India. Though not mentioned in the Nighantis, the us root, decorticated and dried, is in general use in India ‘the names of Suffed-muisli, Dholi-musali, or Ujli-misali. sommercial article consists of shrivelled Seco Piokted tubers, to 24 inches long, the largest being about } inch in ; they are of an ivory white colour, often twisted, hard ; adhering to some of the pieces may be'seen portions owish epidermis; when soaked in water they swell up me spindle-shaped, the thickest part being about the alead pencil. Under the microscope these tubers present te cellular structure, the cells of which contain nothing vascular column, the middle part of which is entirely sd by jointed vessels, the outer portions consisting of e silicious. Suffed-misli has an agreeable mucilaginous have used it largely as an article of diet; it is far Salep, and is generally relished by Europeans. To t, take 200 grs. of the powder, 200 grs. of sugar, pour em slowly a large teacupful of boiling milk, stirring all the time. The best white picked roots are worth per maund of 374 lbs. 1 composition.—The powdered roots were examined the previous article, and were found to contain— 77°55 us 12°85 ci. O'UO avai 3°60 100-00 - extract was a thick mucilaginous liquid which white flocks of albuminous matter when boiled, and by Fehling’s solution. The portion of the Toot er consisted of almost pure cellulose. — 486 LILTACE A. ASPARAGUS OFFICINALIS, Linn. Fig.— ng. Bot., 339 ; Blackw., t. 332 ; Sperage, Asparagus (Eng.), Asperge (F7.). Hab.—Europe, Southern Russia, Turkey, Cries in Persia and Northern India. The plant, root, and ripe fruit. Vernacular.—The fruit, Haliyun (Jnd. Bazars). , History, Uses, &c.—Asparagus was well known to the Greeks and Romans both wild and in a cultivated state. Hippocrates mentions it in his treatise on diet, and in his treatise on the Diseases of Women he says that the berries taken in wine promote conception. Dioscorides and Pliny describe its medicinal properties, and Cato (De re Rust. c. 161) gives full directions concerning its cultivation. The ancients considered it to be a wholesome vegetable, dispelling flatulency and acting as a mild aperient, diuretic and aphrodisiac. They administered the root in wine for calculous affections and pains in the uterus, and also considered it beneficial in elephantiasis. Ibn Sina calls it S) yx; halién and quotes Galen’s opinion of its medicinal value. The Western Arabs call - Isferdj ; in Persia it is known as Mérchubeh and Mérgiyeh “snake wort,” from its being considered to be an antidote for snake poison. Wild asparagus, the A. tenuifolius of Linneus, was known to the Romans as Corruda, a name still current in the south of France, where the plant is valued for its medicinal properties up to the present time. Broussais considered asparagus to be a sedative in palpitation of the heart, and it is still used in France as @ diuretic in cardiac dropsy and chronic gout. ‘The young shoots when eaten as a vegetable are well known to communicate a peculiar and offensive odour to the urine, a syrup for medicinal use is prepared with their juice, 100 parts after clarification being added to 190 parts of sugar. Some physicians consider asparagus to be useless as a diuretic and even injurious to the bladder, but as far as our experience goes it has no ill-effects when taken daily for a considerable time. Indian Mahometan writers on medicine merely retail — : LILIACE. . what the ancients have said about this plant; they usually prescribe the dried berries which are to be found in the bazars - of all large towns. Description.—The root consists of a short horizontal rhizome about } of an inch thick, the upper side is scaly and marked by stem-scars, below it gives off numerous long, whitish, nearly simple roots, which on drying become much wrinkled. It has hardly any odour and a mawkish sweet taste. The ber- ries are scarlet, about the size of a pea, 3-celled, one or two of the cells often abortive, seeds 1-2 in each cell, globose, with a horny albumen, and a transverse embryo, far out of the centre. Chemical composition.—Examined by Dulong, the root was found to contain yellow resin, sugar, gum, albumin, chlorides, phosphates, malates, and acetates. Vanquelin and Robiquet (1805) discovered asparagin in the shoots, a substance which has since been found in many other plants. Reinsch (1870) found in the berries much grape sugar and spar gancin, an matic resin, erystallizable sugar, and a crystalline bitter prin- ciple, spargin. Asparagin, C*H®N°O°H*%O, forms colourless, inodorous, and nearly tasteless crystals, which are insoluble in strong alcohol and ether. It unites with both acids and alkalies, and when boiled with them is converted into aspartic acid, C*‘H’NO‘, and ammonia. Nitrous acid converts it into malic acid, C+H°O*, water and nitrogen. For further information concerning Asparagin, the reader is referred to Watts’ Dict. of Chem., 2nd Ed., 1., 325. The mean of four analyses quoted by Kénig gives the fol- lowing as the proximate composition :— Water . 93°75 per cent. cede 1D) os Fat "25 ” Sugar ..... Ue Nitrogen hi free extractive w26 “Cellulose 1:04 ,, oa ° oe > 488 LILIACEA. The anhydrous plant contained 4°61 per cent. nitrogen, and 42-08 per cent. carbohydrates. ALLIUM SATIVUM, Zinn. Fig.—Bentl. and Trim., 280; Woodville, t. 256; Reich. Ic. Fl. Germ. z., t. 488. Garlic (Eng.), Ail (Fr). Hab,—Central Asia. Cultivated throughout India. The bulbs, Vernacular.—Tasan, Lahsan (Hind.), Rasun, Lashun (Beng.), Vallai-pindu (Zam.), Vellulli (Zvi.), Beliuli (Can.), Lasuna (Mar., Guz.). History, Uses, &c.—Garlic is used as a condiment and medicine by the Hindus. In the Raja Nirghanta it is described under the name of Rasona, and bears many synonyms indicative of its properties, such as Ugra-gandha “strong smelling,” Mahanshadha “ panacea,” Bhuta-ghna ‘‘ destroying demons,” Lasuna, &c. The Hindus consider it to be tonic, hot, digestive, aperient, cholagogue, and alterative ; useful in cough and phlegmatic affections, fever, swellings, gonorrhea, piles, leprosy, colic, rheumatism, and worms. During its use the diet should consist of wine, meat, and acids. A decoction of garlic in milk is givenin small doses in hysteria, flatulence, sciatica, and heart disease. A compound garlic powder called Svalparasona pinda, which contains garlic, asafootida, cumin, rock salt, sonchal salt, ginger, long pepper, and black pepper in equal proportions, is given in doses of about twenty grains every morning with a decoction of the root of the castor oil plant, in facial paralysis, hemiplegia, sciatica, paraplegia, and convulsive affections. Garlic juice is applied externally as a counter-irritant. As a condiment, the bulbs are largely used in the East. Garlicis the oxdpotey of the Greeks and Allium of the Romans, who appear to have used three kinds, A. sativum, Linn., A. oleracewm, Linn., and A. ursinum, Linn. It would be tedious to recapitulate all the medicinal properties ascribed to these plants by the ancients, as they hardly differ from those accorded to LILIACER, 489 arlic by the Hindu physicians. A summary of them may 2 found in Pliny (xx., 23). Garlic is the ¢ »> (thiim) of the bians and _»3~ (sir) of the Persians; their medical writers fol- the ancientsin mentioning three kinds, viz., Bustani “garden,” i “wild,” and Kirdthi “leek-like,” and in the account. 1ey give of its medicinal properties. The leek-like garlic is robably meant for the bulbed leek (Porrwm capitatum) of pocrates (De Morb. Mul., ii., 89) which was considered to e the property of opening the uterus when contracted, and Gubernatis states that in Sicily garlic is still placed upon beds of parturient women. He also notices the wide-spread ' in the protective power of garlic against evil influences mong the Hindus, Scandinavians, Greeks, and Germans, s shown by passages in Sanskrit works, in the Songs of urdrifa and Helgi, the Volsungasaga and Hippocrates. In ogna, at the present day, it is purchased by every one on the st of Saint John as a guarantee against poverty during the whence the proverb : Chi’n compra i ai al de d’San Zvan, Bi povret tot gl’an. (Myth. des Plant., ii., 7.) Garlic is still used medicinally to some extent.on the Con- t of Europe and in America, but in England it is hardly prescribed. A syrup of garlic was formerly official in Dublin Pharmacopwia, and was given in doses 0! two os rachms in moist asthma. Asa condiment, it enters into the composition of most sauces. After intense fatigue a clove of tlic slowly chewed, and swallowed, acts as a very powerful restorative. Description. —Garlic is a sub-globular compound bulb, surrounded by a few dry membranaceous scales, which cover the remnant of the upright stem and the 5 to 8 small bulbs . or cloves arranged in a circle around its base. These bulblets are oblong in outline, compressed from both sides, wedge-shaped toward the stem, and rounded upon the back. They consist of few thick fleshy scales and a short fleshy axis. Garlic has a peculiar pungent and disagreeable odour, and an acrid, burning aste. It is used in the fresh state only. / L623 490 LILIACEA. Chemical composition.—Besides cellular tissue, garlic contains between 50 and 60 per cent. of water, 35 per cent. of mucilage, some albumen, sugar, starch, and about + per cent. of volatile oil, to which its odour and taste are due. W. Dahlen gives the following as the percentage proximate composition :— Water 64°66 Albuminoids 6°76 Fat "06 Sugar trace. Nitrogen free extractive 26°31 Cellulose 77 Ash is 1-44 Anhydrous garlic contained nitrogen 3:06 per cent. and carbohydrates 74:45 per cent. (Landw. Jahrhiicher, 1874.) In its crude state oi! of garlic is of a dark brown-yellow colour, heavier than water, of a very repulsive taste, and consists of oxide and sulphides of allyl, The rectified oil consists mainly of the sulphide, (C*H*)2S, is colourless, lighter than water, and may be obtained artificially by treating an alcoholic solution of potassium sulphide with allyliodide. It dissolves easily in alcohol and ether, and sparingly in water ; with nitrate of silver, mercuric chloride, and other metallic salts it forms crystalline compounds. Garlic, macerated in water or vinegar, yields its virtues to these liquids. (Stidlé and Maisch.) Allylic sulphide can also be obtained from the herb and seeds of Thiaspi arvense, together with sulphocyanide of allyl, and oil of mustard. The leaves of Sisymbrium Alliaria yield oil of garlic, and the seeds oil of mustard. A mixture of these two oils is also yielded by Capsella Bursa-pastoris, Raphanus Rapha- mstrum, and Nasturtium. In some cases the oils do not exist ready formed; for example, the seeds of Thiaspi arvense emit no odour when bruised, and they must be macerated in water some time before distillation. ( Watts.) __ Commerce.—Garlic is cultivated all over India, and is on sale in every grocer’s shop. No statistics are available as to the LILIACBA. 491 juantity produced in India, which must be very large. Value, - bout Rs. 8 per cwt. ALLIUM MACLEANI, Baker. Fig.— Bot. Mag., 6707 ; Hanbury, Sci. Papers, p. 156—57. Royal Salep (Eng.). Hab.—Persia, abundant in the Badghis. The bulbs rought to India by Afghans in small parcels along with the ied fruit and other articles for which they find a sale in the ndian Bazars. A solitary specimen of the dried bulb was t to Hanbury by Dr. J. E. Stocks, but did not at the time attract attention. In 1858, however, a parcel containing about 00 Ibs. having been offered for sale in the London market, nbury recognised the drug as identical with the bulb he had Teceived from Dr. Stocks as Badshah Saleb, and described it in the N. Repert. f. Pharm., vii. 271. In India the drug is regarded as a kind of salep, and is used as such, but, as Hanbury remarks, its bitterish somewhat acrid taste quite unfits it as a substitute for salep in Europe. The botanical source of the drug was discovered by Dr. Aitchison in 1888. _ Description.—Royal salep consists of dried bulbs whose dimensions from base to apex vary from 1} to 2 inches. The largest specimens weigh 730 grains: the average weight, taking twenty bulbs, was found to be 337 grains. Allowing for con- _ Siderable irregularity occasioned by drying, the form of the dried bulbs may be described as usually nearly spherical, some- times ovoid or nearly oblong, always pointed at the upper extremity, and having at the lower either a depressed cicatrix, or frequently a large, white, elevated, scar-like mark. Their 492 LILIACEM. . surface is striated longitudinally, besides which there is mostly one broad and deep furrow running in the same direction. They are usually translucent, and from yellowish-brown to deep purple in colour. In substance the bulbs are dense and horny. After several hours’ maceration in water, they become soft, opaque, and of a slaty or purplish hue, and increase greatly in volume, regaining their natural size and form. If, in this state, a bulb be cut longitudinally into two equal portions, it will be seen to consist of a single fleshy envelope or scale of excessive thickness whose edges overlap each other; this scale surrounding an elongated, flattened bud. (Hanbury.) Chemical composition.—The powdered bulbs, unless kept in well-stoppered bottles, readily absorb moisture from the air. A decoction is not coloured with iodine, but is precipitated with solutions of ferric chloride and plumbic acetate. No reaction for glucose is produced by boiling with Fehling’s solution. The ash contained manganese. The powdered bulbs afforded moisture 8-1] per cent., mucilage (water extract) 80-80, cellulose 7-14, and mineral matter 3-95 per cent. Allium xiphopetalum, Aitcs. et. Baker, Trans. Linn. Soc. 2nd Ser. Botany, Vol. IIL, Pt. 1, pl. xlviii., yields the Thém-el-bari or “ wild garlic” of the Arabs. It bas a bulb resembling Badshah Salep in shape and appearance, but much smaller, a powerful garlic odour, and is much used for pickling by the natives. Large quantities are imported. It appears to have been sometimes confounded with Badshah Salep. In Persia it is known as Sir-i-piazak or ‘onion garlic.” Aitchison found it growing abundantly in the Badghis. In Bombay it is best known as Muscat garlic, from its being shipped from that port. Allium ascalonicum, the Shallot, is called by the natives Ek-kénda-lasun or Ekla-kali-lasan, “one-clove garlic,” and is used by them to cure earache, a small piece being placed also fried in butter and preserved in honey as an aphrodisiac, f ee LILIACEA. er Polianthes tuberosa, Linn., Bot. Mag., t. 1817 ; Bot. Reg., t. 63—Vern. Gulshabbo, Gulchér{ (Hind., Bomb.), Raja nigandha (Beng. ), is the Tuberose of the English, the Fudia- pipa of the Portuguese, and the Amica nocturna of Rumphius (Amb., v., t. 98); it is a common garden flower, considered by the natives to be hot and dry, diuretic,and emetic. The bulbs _ are used as a remedy for gonorrhea. In the Concan they are _ Trubbed with turmeric and butter and applied to remove aat _ (Watiya), small red pimples which often trouble new-born : children. They are also rubbed into a paste with the juice of D is cultivated in France; it sometimes emits phosphorescent flashes of light in the night. SANSEVIERA ZEYLANICA, Wiiid. Fig.— Rozb. Cor. Pl. ii., t. 184; Bot. Reg., t, 160; Rheede, _ Hort. Mal. wi., t. 42. Bowstring Hemp (Eng.). Hab.—Indian Peninsula. The leaves and root. Vernacular.—Murahri, Marél (Hind.), Murba, Gordchakra = (Beng. ), Marfl-kélang (Zam.), Ish4ma-koda-nar (Te/.), Ghan-— asphan, Morvel (Mar.), Katu-kapel (ai.), Heggurutiké (Can. ), Murvel (Guz.). History, Uses, &c.—This plant is the Marv of Sans- lait writers ; it is mentioned by Manu (ii., 42, 44) as the source of the fibre from which the bowstrings and girdle (maurvi) of the Kshatriya or warrior caste of Hindus was made. In the a sweet juice, ” Sniehda- i “having glossy leaves,” Prithak-parni “ diverse-leafed,” Pilu-parni, &c., and is described purgative, heavy, sweet, pungent, tonic, and cardiacal; a y for bile, heat of blood, gonorrhaa, tridosha (a corruption ADA LILIACE ZA. of the three humors), thirst, heart disease, itch, leprosy, fever, rheumatism, and glandular enlargements. Rheede gives the following account of its medicinel uses in Malabar :—“ Folia trita et in formam boli redacta, adversus opthalmiam et oculorum suffusionem assumuntur : cum radice addito Allio ac Auripigmento in oleo Sergelim decocta, gonorrhewam sanant, si nempe caput cum oleo illo illinatur. Bulbus cum Sandalo citrino et butyro bubulino tritus linimentum exhibet, in nervorum con- tractionibus et ardoribus adhibendum. ‘Tota denique planta oleo butyroque incocta omnium acculorum vitia emendat.” Ainslie (Mat. Ind., ii., 192) remarks :—‘“‘ This fleshy creeping root is, ina slight degree, warm to the taste, and of a not unpleasant odour ; and is prescribed, by the native practitioners, in the form of an electuary, in consumptive complaints and coughs of long standing, to the quantity of a small teaspoonful twice daily. The juice of the tender shoots of the plants they administer to children to clear their throats of viscid phlegm. e plant is cultivated in great abundance at Cumbum, and on the Vursenand Mountains in the Dindigul District.” Description.—Root perennial, stoloniferous. Stolones as thick as the little finger, running under the ground, inserted in sheathing scales. Stem none. Leaves radical, from four to eight, the exterior ones shortest, spreading most, and considerably broader, the interior ones nearly erect, from 1—4 feet long, semi- cylindric, grooved on the upper side, each ending in a round, tapering, sharp point; they are all coloured with deeper and lighter green, and somewhat striated, but otherwise are smooth. Scapes issuing from the centre of the leaves, from 1—2 feet long, including the raceme, or flower-bearing part, erect, round, smooth, about as thick asa small ratan, between the raceme and the base these are at regular distances, four or five pointed, alternate sheaths. Racemes erect, about as long as, oF longer than, the scape below the flowers, striated, smooth. Flowers middle-sized, greenish-white, erect, collected in fasci- cles of from 4 to 6, on little, regularly distant tuberosities of the rachis. Bracts small, membranaceous. Pedicels clubbed, short, ascending, one-flowered. Calyx none. Coralla one-petalled, LILIACEZ. 495 not in the least wrinkled, funnel-shaped, half six-cleft; _ divisions nearly linear. Filaments length of the divisions of the coralla, and inserted into the base. Anthers linear- oblong, incumbent, half two-cleft, Germ 8-lobed, 3-celled, each containing a single ovule, attached to the axis. Style length of the stamens. Stigma 3-sided, clubbed, entire. Berries 1—8, slightly united; when single, globular, fleshy, -orange-coloured, smooth, the size of a pea, one-seeded. Seed _globubar. Embryo simple, lodged near the base of the peri- sperm on the outside. (Rorburgh.) Chemical composition.—An alcoholic extract from the fresh bots was mixed with water acidulated with sulphuric acid, d agitated with petroleum ether, ether, then rendered alkaline d reagitated with ether. ‘The petroleum ether left on spontaneous evaporation a viscid, htly greenish-yellow residue, with a ginger-like odour, milar to that of the fresh roots. The extract was partly uble in absolute alcohol, the solution possessing a pungent inger-like taste and acid reaction. The portion insoluble in hol was white and had the properties of a wax. The acid ether extract had a fragrant vanilla-like odour and yellowish-green. It contained salicylic acid, a yellow hol: the nature of this principle was not ascertained. The kaline ether extract contained a crystallizable white alkaloid, tording a slight yellowish-red colour with Fréhde’s reagent d the cold, changing to blue on warming; and, with nitric ee faint yellow coloration. We provisionally name this oid Sansevierine. HERMODACTYLUS. Vernacular, —Surinjin (Ind. Bazars). pe story, Uses, &c.—The Hermodactyl, or ‘“ Finger of lermes,”’ was pees to the early Greeks; it appears to 2 been first used medicinally by the Arabs or later Greek = 496 LILIACE&. physicians ; it is first mentioned by Alexander of Tralles, who flourished A.D. 560. (Lib. XT.) It is deserving of special notiee that under the name of Surugen or Hermodactyl, Serapion comprehends the «eAx:xey and «dnpepov of Dioscorides and the eppodacrudos of Paulus Algineta.* (Pereira, Vol. IL, Pt. L, p- 166.) Masih and other early Arabian writers describe three kinds of Hermodactyl, the white, yellow, and black; in this they are followed by most of the more recent Mahometan writers. According to Ibn Sina, the flower of the Surinjan is the first flower which appears in spring in the moist valleys beneath the mountains; the leaves, he says, lie flat upon the ground, the flowers are yellow and white. Mir Muhammad Husain states in the Makhzan that the white is the best, and that it is not bitter ; next the yellow ; both may be used internally ; the black, he says, is poisonous and only to be used externally. He describes the Hermodactyl plant as having leaves like a leek and a yellow flower; it is called in Persia Shambailid ; the black _ variety, he says, has red flowers. _ Aitchison states that the corms of Merendera persica (Boiss. ), a plant with pale pink or white flowers, are sold at Meshed as Shambalid, and are one of the kinds of Hermodactyl; they may occasionally be mixed with those of Colchicum speciosum (Stev-), also a common plant in the Badghis and Kliorasan. The Kashmir Hermodactyls ( Surinjan-i-talk ) are, he says, uD- doubtedly the corms of Colchicum luteum (Baker). Mahonictan physicians consider the drug to be deobstruent, alterative, and aperient, especially useful in gout, rheumatism, liver, and spleen. In gout they combine it with aloes: with ginger and pepper it is lauded as an aphrodisiac; a paste made of the bitter kind with saffron and eggs is applied to rheumatic and other swellings ;, the powdered root is sprinkled on wounds to promote cicatrization. Two kinds of Surinjén are met with in Indian shops, bitter and sweet, European physicians in India who have tried the drug consider the sweet Hermodactyl to be inert or nearly so, and the bitter to have properties similar to — 4 Colchicum. (Phar. of India, p. 246.) * Conf. Dios. iv, 82, 83. Paulus ZX. iii., 78. LILIACE A. 497 Description.—Sirinjén-i-shirin, or tasteless Hermo- dactyl. Speaking of this drug as furnished to him from India by Dr. Royle, Pereira says :—‘‘In their general form these corms resemble those of Colchicum autumnale, They are flattened, cordate, hollowed out or grooved on one side, convex on the other. At their lower part (forming the base of the heart) is a _ mark or-disc for the insertion of the root fibres. Their size varies; the specimens I have examined were from 3 to 14 inch in length or height, 1 to 14 inch in breadth, and about } an inch in depth. They have been deprived of their coats, are externally dirty yellow or brownish, internally white, easily _ broken, farinaceous, opaque, odourless, tasteless, or nearly so, _ and worm-eaten. They agree precisely with Hermodactyls furnished by Professor Guibourt.”’ bok be a re EE TL eT, 2s the root fibres.” (Mat. Med., Vol. I1., Pt. L., p. 167.) Pereira’s description agrees exactly with the Hermodactyls which we have examined. Microscopie structure.—The starch grains of the tasteless 4 Hermodacty] are large and muller-shaped, with a distinet hilum. The starch of the bitter kind is angular by compres- ‘Sion of the cells, and appears to be broken as if by heat. Chemical composition.—Lecanu has analysed the tasteless ety, and obtained the following result :—Starch (forming the ee : IIh—63 * 498 LILIACEA. bulk of the drug), fatty matter, yellow colouring matter, gum, supermalates of lime and potash, and chloride of potassium. We have made comparative analyses of the Bitter Surinjan from Lahore and the Sweet Surinjan (Merendera persica). Bitter. Sweet. Ether extract 131 °69 Alcoholic extract 54, 6°23 Water extract 12°56 12°52 Starch 65°00 65°90 Cellulose ot Oe 3°56 Ash 2°20 2°15 Moisture... : 9°75 8:95 The ether extract of the bitter Surinjan contained a resin giving a rose-red colour with sulphuric acid. The ether extract of the sweet kind consisted of fat. Both drugs contained an alkaloid giving precipitates with tannin and the x usual reagents, and both contained an organic acid related to q malic acid. A much larger quantity of Fehling reducing ’ principle was present in the sweet than in the bitter drug, and this is shown in comparing the amounts of extract dissolved out by alcohol. Commerce.—Bitter Hermodactyls are imported into India _ from Kashmir. The sweet kind comes from Persia. Value, Re. 1-4-0 per lb. Substitute for the Bitter Hermodactyl.—The sliced bulb of Narcissus Tazetta (the true N. arcissus), a plant which, when in loom, covers like a white carpet great portions of the plains of Behbehém and valley of Sha’b-bawan in Persia, is imported into India as bitter Hermodactyl. It may be at once detected by its larger size and tunicated structure. The taste is bitter and acrid, the substance amy- laceous and very similar to that of the Hermodactyl. The starch grains are rounded and not compressed. It is used as — an external application, and, according to the author of the Makhzan, has properties very similiar to those of Sirin- — jan-i-talkh, The several species of Narcissus (Gr. vapxioos) LILIACED. 499 have asimilar action. Pliny describes their emetic, purgative, maturative, and drying powers, and, referring to their soporific virtue, says, “et a narce narcissum dictum non a fabuloso puero.” The Arabs give a similar account of them. Orfila’s experiments upon dogs show that they act as local irritants, _ and also exert a depressant and paralysing effect upon the brain and whole nervous system. In man small doses are - emetic ; recently from 15 to 30 grains of the flowers of the common daffodil have been recommended as an emetic for children. ° The following is an analyses of the corms of Narcissus —— Lazetta :— iB fete ae Ether extract .. "39 Alcoholic extract 1:02 Water extract. ve 10°24 Starch ee 6 go Cellulose 3°84 Ash pene Moisture 7 see ARTO The ether extract was fragrant and greasy. The alcoholic extract contained an alkaloid, bitter and acrid in taste, and a -Tesin, Malic acid was present. HIRANYA-TUTTHA. This substance bears a Sanskrit name fetva gy “ golden collyrium,” which, in the vernaculars, is converted into Haran- tuttha or Haran-tutiya. It is a medicine of great repute in Afghanistan and Northern India, and is @ dark-brown dry extract, sold in small pieces, which is prepared from the corms Of Colchicum luteum (Baker), and possibly from other species of Colchicum. In Sanskrit Tuttham or Tutthénjana is a term applied to collyria made of sulphate of copper or of the root of 4 plant with a yellow flower, which has by some been supposed 500 LILIACEA., to be a Curcuma, but which is undoubtedly Colchicum luteum, a plant found in the Punjab, Afghanistan, and Kashmir. C. Masson, in his narrative of an Excursion into the Hazareh Country in 1832 (Zrans.Bombay Geograph. Soc. ii., p. 60), notices a small bulbous root, which the Afghans dug up at B4d Assiar on the banks of the Helmund, and which appeared to be a kind of Colchicum, for the purpose of preparing Haran-tuttha, a medicine of great repute among the Afghans. He also re- marks :—“ It is sold in small pieces of adark-brown colour, and resembles a dry extract.” Masson travelled through a great part of Afghanistan on foot, mixing with all classes of the people, and his experience of their manners and customs is very interesting. : SMILAX CHINA, Linz. Fig.—Kempfer Amen., t. 782. China root (Eng.), Squine (Fr.). Hab.—China. SMILAX GLABRA, ozs. Fig.—Seeman, Bot. of the Herald, tt. 99.—100. Hab.—Sylhet, Garrow Hills, §. China. The tuberous roots. Vernacular.—Chob-chini (Ind. Bazars), Too-fuh (Chin.), San- kira (Japan), Oay-khue-khae (Coch.-Chin.), Paringai-puttai (Zam.), China-pagu (Mal.). History, Uses, &c.—This drug was introduced into Goa from China about A.D. 1535 (Garcia). Previous to this date it isnot noticed by any of the Mahometan physicians. The Portuguese, however, appear to have lost no time in carry- ing it to their factories in Persia, as it was mentioned, a few years after its introduction into Goa, by Mir Imad-ed-din Mah- mud of Shiraz, Mirza Kézi of Yezd, and Mir Muhammad Hashim of Teheran. In 1669 it was described as a well-known drug in the Tuhfat-el-muminin under the ‘name of Chib-c i i LILLACE AM, | (Chinese wood), in Arabic Khashab-es-sini. The author of the Makhzan-el-Adwiya has a long article upon its medicinal virtues, _ He also notices particularly the variable appearance of different samples of the drug, and directs that what is heavy, of a rosy colour, and free from knots is to be selected. He tells us that the fresh root is sometimes brought to India; some of this he planted at Moorshedabad (A. H. 1178) ; it produced a climbing _ stem with small elongated leaves, not unlike a bamboo; after a _ year’s time he dug it up, but found that the roots had degene- vated and did not retain the qualities of the China article. _ Chub-chini is considered by these writers to be anti-rheumatic, _ anti-syphilitic, aphrodisiacal, and demulcent. Loureiro says of it, ‘valet in quibuscunque doloribus vagis, venereis, aut : rheumaticis,” Ainslie (Mat, Ind., i., 70) notices its use in Southern India as an anti-syphilitic and as a remedy of much repute in a disease alled maygum vaivoo, in which the limbs are stiff and contracted. He also states on the authority of the Abbé Rochon* that “the Chinese often eat the root instead of rice, and that it contributes s called Husina-shook-China, has large tuberous roots, not to be distinguished by the eye from China-root, and that the natives of the country use a decoction of the fresh root for the eure of Sores and venereal complaints (Flora Indica). This plant also _gTows in China and affords some of the China-root of commerce. (Trimen’s Journ. of Bot., i, 102.) __ The reported good effects of China-root on the Emperor Charles V., who was suffering from gout, acquired for the drug @ great celebrity in Europe, and several works were written in praise of its virtues. But though its powers were soon found to have been greatly over-rated, it still retained some reputation as a sudorific and alterative, and was much used at the end of the 17th century in the same way as sarsaparilla. It still Tetains a place in some. modern pharmacopeias. (Pharma- cographia.) Re Vorcete Madagascar and the East 1 Indies, London, 1792. 502 - LILIACE. In the East, Chub-chfni is still as highly esteemed as it ever was, and the China Trade Returns show a steady yearly increase in the quantity shipped from Southern China. Description.—The tubers, which are formed upon the fibrous roots of the plant, are of the shape and size of an elongated kidney potato, somewhat flattened, knotty, covered with a rusty-coloured bark, sometimes smooth and shining, sometimes rough; internally their substance is of a pink- ish-white colour, hard and farinaceous, insipid, mucilaginous and inodorous, The drug is usually peeled and trimmed, and consequently is of irregular form, resembling a piece of heavy pinkish-white wood, Microscopic structure—The bark consists of thick-walled dark-brown brick-shaped cells, which contain bundles of crys- talline needles and resinous matter. The bulk of the tuber is made up of a parenchyma, the cells of which are large, thin- walled, and loaded with starch, some pink colouring matter is also present. The starch grains are large and have a radiate hilum. The vascular system is scalariform, and is associated with porous wood cells, Chemical composition.—The authors of the Pharmacographia endeavoured to obtain from the drug Parillin, the crystalline principle of sarsaparilla, but without success. A proximate analysis of the air-dried drug afforded :— Ether extract (fat) 0°33 Alcoholic extract (sugar, glucoside)......... 1°72 Aqueous extract (sugar, gum, &c.) ..... oc ae Crude fibre 13°79 ee 1-47 Moisture ..,.. seaas 6°10 Starch (by difference) 69°80 100-00 LILIACEZE, 503 This root contained no alkaloid, but the alcoholic extract contained a glucoside, and a colouring matter which gave an olive-green tint with ferric chloride, but no precipitate with gelatine. With soda it afforded a deep red colour, and was pre- cipitated from solution by neutral plumbie acetate. The sugar present abundantly reduced Fehling’s test without previous inversion. The amount of ash, consisting of alkaline salts is very small. Professor Kobert has recently separated from true sarsa- parilla three glucosides, smilacin, sarsasaponin, and parillin,— these compounds differ in physiological activity,but are members _ ofa homologous series to which has been assigned the general formula C" H?"=—80*°, Commerce.—From 16,000 to 17,000 peculs of 133 Ibs. each are annually produced in Southern China. The greater part is consumed in China, but a very considerable portion must reach India, as the drug is to be found in every bazar throughout the . _ country. Smilax ovalifolia, Rozb., Rheede, Hort. Mai. vii., t.31, Jangli-ushbah (Hind.), Malai-timara (Zam.), Konda-témara (Zel.), Gatwel, Git (Bomb.), Kal-témara (Ma/.), is a climbing shrub very common inthe Concans. The roots are very humerous, and have a general resemblance to sarsapari section shows a dry, suberous, brown bark ; secondly, one row of 5-sided yellow cells, which are more or less wedge-shaped, _ their nuclei being situated towards the apices ; thirdly, a range of numerous rows of ovoid cells, variable in size, with central nuclei; these extend as far as, and partially surround, the vascular zone, which consists of large vessels with generally two smaller ones in contact with them. Within the vascular zone the central portion of the root is made up of large thin- walled cells, filled with starch or red colouring matter; the latter is most abundant in young roots. The drug is not used by the natives, but in Goa it is kept in all the shops, and is the country sarsaparilla of the Portuguese. 504 LILIACE. DRACZENA CINNABARI, Balf. f. Fig.—Balf. f. in Trans. Roy. Soc. Edin. xxxi., Tab. xevi—xevii. Dragon’s blood (£ng.), Sang-dragon (£7.). Hab.—Socotra. The resin. Vernacular.—The tree—Kharya (Socotra). The resin—Dam- khoheil, Edah (Socotra), Dam-el-akhwain (Arab., Ind. Bazars), Hira-dukhi (Hind.), Hira-dakhan (Bomd.), Kandamurgarittam (Zam.), Katgamurgam-nittiru ( Ze/.). History, Uses, &c.—On the Deir-el-Bahari monument at Thebes, erected by Hatasu, a queen of the 18th dynasty, who lived about 1700 B.C., there are representations showing the commissioner of the queen going over the sea to the country of Punt and of ‘ To Nuter,’ and bringing therefrom, amongst other things, plants bearing ‘ Ana,’ which is shown as a gum or resin in the form of red tears on the stems of small trees with ovate-lanceolateleaves. The To Nuter of the inscription has been identified with the Sacred Islands of Pliny, and the modern archipelago, including Socotra. The gum or resin is probably dragon’s blood, as that is the most remarkable substance of the kind produced on the island. The author of the Periplus of the Erythrean Sea, A.D. 54-68, mentions cwvd8ap: as a produc- tion of the island of Dioscorida, the ancient Greek name of Socotra. Dioscorides (v. 63) notices its medicinal uses under the same name, and states that it is produced in Libya (Africa). Both he and Pliny (33, 38) distinguish it from the mineral cinnabar; the latter writer states that the price of genuine cinnabaris is fifty sesterces per pound. A myth was current among the Greeks and Romans that this substance was the blood of the dragon or python crushed beneath the weight of the dying elephant, round which it had wound itself to suck the animal’s blood. Rufus Ephesius and Galen notice the use of the drug for stopping hemorrhage from _ wounds, on +58 LILIACE@. 505 Among the Arabs it bears many names, such as Dam-el- akha-wain, Shayydn, Aidé vulg. Edi, Dam-el-tinnin, and Dam- el-thuabin “dragon’s blood,” Eléndam, Katir-ed-dam, and later El-katir-el-makki vulg. Katr-makkeh. Johanna-bin-Masa- wiyeh, physician to the Caliph Haroun-el-Rashid, specially recommends it for strengthening the stomach and liver, and as _ an astringent ingredient in collyriums. On account of its. use as a collyrium, the Arabs sometimes call it Dam-kuhl or simply _ Kuhl “collyrium.” Among the Persians it is known as Khin-i-siy4wash, and they have a myth that when Afrdsidb killed Siydwash, this _ plant sprung up upon the place where his blood was shed. The author of the Burhén, who relates this story, also remarks that the gum is said to come from Africa. Haji Zein (1368) notices three qualities of dragon’s blood, viz., Chakideh ‘ drop,’ Turdbi “earthy,” and Khashabi ‘ mixed with wood.’ He says it is not the gum of the bakam (Cesulpinia Sappan) as supposed by Some, but of a tree growing in Africa. The author of the fat-el-muminin states that the plant which produces it is not known; he notices its use for painting glass. The author aM Makhzan (1770) merely repeats what older writers have Said, eee ae Ainslie (Mat. Ind., i, 113) remarks that it is often con founded with Kino by the native doctors of Lower India. The Tamool doctors recommend a solution of it in arrack as _ 2 external application to the head and temples in cases of Syncope. Although the early European travellers in the Fast Mention Socotra dragon’s blood, Guibourt and Pereira do Rot notice it, and nothing exact regarding its source was known until Wellstead (Journ. Roy. Geog. Soc., v. (1835), 198) “rite the tree, but wrongly supposed it to be Pterocarpus “TACO, Professor Bayley Balfour, who visited Socotra a few years examine the fauna and flora of the island, was the first 506 LILIACE®,. to give us any exact information concerning the species of Dracena yielding dragon’s blood in Socotra, and the way in which it is collected. He says, the resin exudes most abun- dantly immediately after the rainy season ; the natives collect it by chipping it off with a knife into a small bit of skin placed against the tree; there are different qualities collected: 1s¢, the large tears, which are the best and most expensive, and are called Hdah amsal (J Got go! best Edah) ; 2nd, small portions which become detached, forming powdery dragon’s blood or Edah dukkah (So o%! Edah dust); 3rd, an inferior kind, obtained by melting the refuse into cakes, called Hdah mikdhah (ra o&e ¢ O21 Edah of the ladle). Description.—The best quality may at once be distin- guished by its occurring in tears, the surface of which is covered by a dull red powder. When broken, the surface is glassy, translucent, and of a beautiful garnet colour. Imitation tears are manufactured in India from the powdery dragon’s blood; they may easily be detected by their wanting the glassy fracture of the genuine article. Cake dragon’s blood is also met with; it is of a dull red colour, and contains fragments of bark- wood, and other refuse. Chemical composition.—See Calamus Draco. Commerce.—The drug is imported into India through Bombay. Zanzibar Dragon’s blood is similar in appearance to that which comes from Socotra, and is not distinguished from it in Indian trade. Hildebrandt has ascertained that it is obtained from the stems of Dracena Schizantha (Baker). The natives remove pieces of the bark about two inches square, and the cavity in two to three weeks’ time becomes filled with the resin. In Zanzibar it is used in opine and is said to be called ‘ Macziwa ya watu wawili,” meaning the milk of two men, or “ Matcho ya watu wanilicce the he o.4 of two men, a BROMELIACEM. 507 BROMELIACEZ. ANANAS SATIVA, Linn. __-Fig.—Bot. Mag., t. 1554; Rheede, Hort. Mal. vi., t. 1. : . Pine-apple (Zng.), Ananas (F’r.). . _ Hab.—America. Cultivated throughout the East. The _ fruit and leaves. Vernacular.--Anannés (Hind.), Andnas, Andras (Beng.), Annis, Aunds (Mar.), Andras (Guz.), Anfsha-pazham (Zam.), Andsa-pandu (Te/.), Kaita-chakka, Parangi-chakka (Aal.), Anfnasu-hannu (Can.). _ History, Uses, &c.—The Pine-apple was unknown i India prior to the discovery of America; it was first made known to Europe by Hernandez in 1513, and was introduced India by the Portuguese from Brazil in 1594. ts introduction is mentioned by Abu Fazl in the Aycen-i- kbari, and also by the author of the Déra Shakoh. The Vernacular names are mostly derived from the American names Anasi and Nanas, but the Malabar name Parungi-chakka fruit is cold and moist, suitable to those of a bilious tempera- ment, but not to the phlegmatic ; to lessen its coldness it should be cut in thin slices and washed in salt and water and after- Wards in pure water ; it may then be sprinkled with sugar and Tose-water and eaten. A little ginger is also said to render the t more wholesome. Pine-apple chutney, preserve, and et are also mentioned, but nothing is said about the 508 BROMELIACEZ. medicinal use of the leaves and unripe fruit. From the special opinions of medical officers in India recorded in the Dict. Econ. Prod. of India (i., 238), it appears that a belief in the aborti- facient properties of the leaves and unripe fruit is common throughout India among the natives. Chevers (Med. Juris., p.715), onthe authority of Babu Kanny Lall Dey, has the following description of its use in Bengal :— ‘\A green, unripe one, only half-grown is used. It is decor- ticated, and the pulpy mass of a whole one is administered to the woman with a small quantity of salt. It is efficacious only during the earlier months of pregnancy; and, after the third month, its action is very doubtful. But, if administered to suitable cases, the uterus begins to contract within twelve hours, when slight hemorrhage occurs also. Its action then in- creases, and within the course of twenty-four hours the ovum is expelled. Occasionally the woman’s life is jeopardized by flooding, but, asa rule, there is not much danger to be ap- — prehended.’’ Again, at page 718, Chevers says: “ A note which I have from Babu Koylas Chunder Chatterjee renders this matter plain. He says that acid fruits are regarded as abortives. He knew a case in which a woman aborted at an advanced stage of pregnancy by eating ( with that intention) about two pounds of ripe pine-apple. This fruit is rendered unwholesome by the presence of a very strong fibre which acts as a mechanical irri- tant on the bowels. I had under my own care an English lady who died of dysentery, after having aborted, at about the fifth month of pregnancy. The cause of her illness appeared to be the ravenous eating of raw pine-apple.”’ Description.—The plant is biennial, not unlike an aloe, but the leaves are much thinner, and of a hard fibrous texture; with numerous short sharp spines on the edges. The fruit 1s produced on a short stem which rises from the centre of the plant, and bears a sealy conical spike, surmounted by a number of small a spiny leaves called the crown. This conical spike bears a neimber of small bluish flowers having three petals and a 3-parted calyx ; after flowering, it gradually enlarges and even becomes a succulent fr ieee tie) A = fruit of a rich orange-yellow © COMMELINACEZ. 509 Chemical composition.—The essence of pine-apple is prepared - rtificially by mixing butyrate of ethyl with 8 or 10 parts of ‘spirit of wine. aii -apple juice contains a proteid-digesting rment. Three fluid ounces digest 10 to 15 grains of coagulated albumen ; it acts equally well in acid and alkaline ‘solutions, and best in a neutral fluid. The juice also contains milk-curdling ferment. The ash has the following composition :— Potash 49°42 per cent, aceaia 880 jy Tim 41m. 12°15 ” Phosphorie acid B08: %, Sulphuric acid trace. BMUICA cas bivslinsi ois 4°02 ” Phosphate of iron 2°93 55 Chloride of sodium 17-01 » Chloride of potassium “88 (Quoted by Kensington in Chemical Composition of Foods, COMMELINACEZE. COMMELINA BENGALENSIS, Linn. Fig.—Clarke, Comm. et Cyrt. 14, pl. iv.; Wight Ic., 2065. Hab.—Bengal, Peninsula, Sind, Concan. The herb. Vernacular.—Kénchara (Hind.), Kéchrédém, Kanchara g-), Chura, Kanna (Punj., Sind), Kena (Mar.), Kanang- -Karai (Tam.), Venna-devi-kura, Niru-kassuvu (Z¢/.), Hittagant Can.), History, Uses, &c.—This and several other species of ommelina are included under the Sanskrit name of Kanchata, Y are small herbaceous plants which appear everywhere s the end of the rainy season and are remarkable for brilliant blue flowers. The stems, roots, and seeds which = 510 XYRIDEZ. contain much mucilage and starch are used on account of their demulcent properties, and are eaten in times of scarcity. CO. communis is said by Loureiro to be refrigerant and laxative, and to be useful in strangury and costiveness. Tradescantia axillaris, Witld., Rheede, Hort. Mal. «., #. 13. A very similar plant, and often called by the same vernacular names, has similar properties, and its seeds have _ frequently proved to be a valuable resource in times of famine. Ainslie notices it under the Tamil name of Nirpulli (Mat. Ind., ii., 250), Lyon found the seeds to have the following percentage com- position :—Water 10°26, fat 0°62, albuminoids 15-99, carbo- hydrates 54°79, cellulose 9°36, ash 8:89. The nitrogen was estimated at 11-28 grains per oz., and the nutritive carbon at 145°80 per oz. He calculates the nutritive value of the seeds as Compared with the average cereal at 100-00 to be 85°76. XYRIDEZ. XYRIS INDICA, Linn. Fig,—Theede, Hort. Mal. ix., t. 71. Hab.—Salt marshes in Bengal, S. Concan, and Coromandel. The herb. : Vernacular.—Dédméri (Hind.), China-ghauza, Dabi-diba (Beng.), Kochilftti-pullu (Tam.), Kochilachi-pulla (Mal.). History, Uses, &c.— Xyris ( évpis) is a name given by Dioscorides (iv., 24) toa species of Iris, which has been identified with fetidissima, Linn. Pliny (21, 83) speaks of the same plant as the wild Iris called by some Xyris; it appears to have been applied locally to disperse scrofulous swellings and to promote the healing of sores, and given internally asa diuretic and alterative. Linneus transferred the name to a genus of flag-like plants growing in the East and West Indies. X. indica does not appear to be mentioned in any of the standard native medical works, but Rheede notices its use in Malabar 17 PALM. 511 the following terms:— “ Foliorum succus cum aceto mixtus impetigini resistit ; folia cum radice oleo incocta contra lepram sumantur ; cum mungo (Phaseolus Mungo, Linn.) decocta et epota somnum consiliant.” Agardh, the Swedish botanist, notices its use as a remedy for itch and leprosy. Ainslie gives the plant a place in his Materia Indica (ii., 125), but merely repeats what Rheede has already said. Roxburgh gives a full _ description of it, and remarks on the authority of the Hon’ble J. Hyde that “the natives of Bengal esteem it a plant of great value, because they think it an easy, speedy, and certain cure for the troublesome eruption called ringworms.’ s Description.—Root fibrous, annual; leaves radical, bifarious, straight, sword-shaped, on one edge slit into a sheath for the scape, pointed, smooth, 6—12 inches long; scape naked, round, striated, erect, length of the leaves, each sup- porting a round, flower-bearing head ; flowers, bright yellow > bracts 1-flowered, orbicular, concave, hard, smooth ; calyx 3-leaved, hid within the scale, membraneous; petals three, each supported on an unguis just long enough to raise their expanding, oval, crenate borders above the scales ; filaments hree ; anthers twin; germ superior, 3-sided; style 3-cleft ; ‘Stigma torn; capsule 3-valved, 1-celled; seeds numerous. (Roxburgh,) Chemical composition.—The plant contains a red colouring ‘Matter soluble in alcohol and intensified by alkalies and having Some reactions peculiar to chrysophanic acid. PALM. COCOS NUCIFERA, Lin. Fig.—Rorbd. Cor. Pl. i., t. 73; Rheede, Hort. Mal. 4., #.°1 to4. Cocoanut (Eng.), Cocotier (F¥.). _ Hab.—Indian Archipelago and coasts of India, The flowers, fruit, shell, oil, fuice, tomentum, root, and ash. Vernacular. —Nirryal (Hind., Beng.), Nariyal (Gus.), Naral, i méd (Mar.), Tenha, Tenna-maram (Tam.), Néri-kadam, piety, +519 PALMA. Tenkaya-chettu (Te/.), Tengina-gida, Tengino-kiyi (Can.), Tenga, Ten-maram (Mai.). History, Uses, &c.—The cocoanut, formerly written coconut, derives its European names from the Portuguese coco, “a mask.” Garcia ab Horta says: ‘“‘ We have given it the name of cogus on account of its having three holes which cause it to resemble the face of a cat or similar animal.” The resemblance, however, of this nut to a head and face had not escaped the notice of the Hindus ; long before the Portuguese had set foot in India, néral was uaa as a cant term in the sense of head, pate, sconce, &c., and was sometimes used to represent the head of a dummy figure by the relatives of a deceased person whose body could not be found, and who nevertheless were desirous of rendering to it the usual funeral rites. Various superstitious uses to which the cocoanut is put in India attracted the notice of the early missionaries. Vincenzo Maria da Santa Caterina (Viaggio alle Indie Orient., iii., 29) states that when an Indian falls sick, they spin a eiddamnut; ; if it stops with its face towards the West, the sick person will die, but if it faces the East, he will recover ; he also notices the offering of a cocoanut at the commencement of any building. To this we may add that on the Western Coast cocoanuts are offered to the Sea on the day of the full moon of Shravan, when the monsoon is supposed to terminate. It is related that in former days the European Governor of Bombay used to go in state and throw a golden cocoanut into tho sea on this day. In Hindustan there is also a practice among the Indian Maho- metans of breaking a cocoanut to ascertain whether a pregnant woman will be delivered of a male or female child; if it is © empty she dag be delivered of a son, if not, of a daughter : this is call “nariyal torna.” Breaking a cocoanut against the wall of a person’s house is in Western India an ne of enmity to the inmates of the house, and is connected with the practice of smelling the heads of children before allowing them to leave the house. The utarna or casting away of © disease or misfortune may be performed by carrying a cocoanut to a distance from the house and breaking it. “oe PAIM ZZ. 513 Among the Hindus the most important function of this nut is t marriages, when it is the custom to place the ¢a/i of the bride, mvulgo dictus Coco, ex cujus fractione prosperitatis vel nfortunii auspicia gentiles temere ducunt, vel omnino a Chris- norum nuptiis regiciatur, vel saltem, si illum comedere velint -publice sed secreto et extra solemnitatem apariatur ab iis 3 evangelica luce edocti, ab hujusmodi auspiciorum delira- to sunt alieni.” In the coast districts, cocoanuts and sugar- e8 (ndral, batasa) are lavishly distributed to the guests on yortant festive occasions, ‘such as marriage, the phool cere- ny on the event of the first menstruation and first pregnancy, | the thread ceremony ; in other parts of India their place upplied by betel-nuts. In Europe nuts appear to have been Z ays regarded as auspicious and symbolical of fertility ; the ee ans peicred nuts at weddings; Virgil says, “ Spar, ite, nuces,” and De Gubernatis states that this custom | in several parts of Southern Europe ; in Piedmont the proverb : Pan e nus vita da spus. : refer the reader to the Dictionary of the Economie Products India (ii., 415), At the Colonial and Indian Exhibition, . C. Pereira, Head Assistant to the Government Medical rekeeper, Bombay, exhibited a collection of eighty-three es prepared from the tree, and we are informed that he Since added considerably to his collection. Skrit medical writers describe the tree under the name la or Narikera, and give it many synonyms, such as Q ae ele “king of grasses,” Skandha-taru 514 PALM ZL. “stem tree,” Dur-droha “ difficult of ascent,” Ktircha-sekh- ara “crowned with a bunch of fruit,” Dridha-phala « having hard fruit,” Rasa-phala “having juicy fruit,” Dridha-nira “having strong juice,” &c. The tree also bears the name of Langala “ membrum virile.”’ Dutt (Mat. Med. of the Hindus, p. 247) gives the following summary of the medicinal uses of the cocoa palm mentioned in Sanskrit medical works:—“The water of the unripe fruit is described as a fine-flavoured, cooling, refrigerant drink, useful in thirst, fever, and urinary disorders. The tender pulp of the fruit is said to be nourishing, cooling, and diuretic. The pulp of the ripe fruit is hard and indigestible, but is used medicinally in the preparation called Nérikela-khanda. The terminal bud of the tree is esteemed as a nourishing, strengthening, and agreeable vegetable. The root of the tree is used as a diuretic, and also in uterine diseases. The oil is said to promote the of the spirituous liquors described by the ancient writers. The cleared shell of the nut is burnt in the fire, and when thoroughly ignited covered up in a stone cup, the fluid thus obtained is rubefacient, and is an effectual domestic remedy for ringworm. The narikela-khanda already mentioned is made in the following manner :—Take of the pounded pulp of cocoanut half a sér, fry it in eight tolas of clarified butter, and afterwards boil in four . 8érsof cocoanut water till reduced toa syrupy consistence. Now add coriander, long-pepper, bamboo manna, cumin and nigella , cardamoms, cinnamon bark and leaves, cyperus root and the flowers of Mesua Fferrea, one tola each in fine powder, and Prepare @ confection. The dose is two to four tolas, in dyspep- sla and consumption. The cocoa palm is supposed by some to have been the _ Keupopioey ( Sévtoor ) of Theophrastus (H. P. iv., 2, 7), and the PALM, 515 uci of Pliny (13,19), but their description appears to agree better with the Hyphene coriacea or Doom palm of Egypt. The Arabs call the cocoanut Nérjil, and the Persians Nargil, adinj, and Rénaj ; their physicians describe it as hot and dry, utritive and aphrodisiacal, beneficial to those suffering from ‘piles; the kernel;when fit has been kept for some time is con- sidered to be anthelmintic. They remark that it is not easily digested, especially when old. European physicians, who have practised in India, reeommend tained by pulping the unripe kernel and expressing it has n recommended as a nutritive diet in debility and cachexia; ‘large doses it is aperient, and Mr. Wood has suggested its se as a substitute for castor oil. (Pharmacopeia of India.) anthelmintic properties of the cocoanut noticed by Maho- fan writers have been confirmed by European observers ; the in plaster-making and in the preparation of soap ed and distilled, yields a clean spirit suitable for ceutical purposes. 516 PALM Zi. .Description.—The cocoa palm, which has now been introduced into all tropical countries, grows toa height of 70 or 80 feet, and has at the apex a tuft of leaves which are twelve feet or more in length and have numerous narrow rigid leaflets. The spathe, from which toddy is obtained, when un- _ disturbed produces numerous yellowish-white flowers succeeded by the fruit, only a small proportion of which come to maturity in about twelve months from the time of flowering. The imma- ture fruit contains a clear sweet fluid, which gradually dries up as the nut ripens. The kernel which lines the interior of the shell, after the nuts have been kept for some time, dries up and sepa- rates from it, and is then called khopra; from it is obtained by hot pressure or by boiling in water the cocoanut oil of commerce, which has a mild, bland taste, a pale yellow colour, and peculiar odour. In hot climates it remains fluid, but when exposed to cold, it becomes of a butyraceous consistence and white colour. 4 Its melting point varies between 22° and 30°C; the cold pressed oil melts at 20°C. or less; the fused, thin, transparent yellowish oil congeals between 18° and 12°C. After having been heated it remains liquid for several days. The oil is readily saponified at a low temperature, the soap being white, hard, and capable of uniting with much water. Chemical composition.—Fresh cocoanut kernel contains water 46°64, nitrogenous substances 5°49, fat 35-93, non-nitrogenous extract 8°06, lignin 2°91, ash 0-97 per cent., and when dried yields nitrogen 1:65 and nitrogen free extract 67°33 per cent. (Konig in Hammerbacher Landw. Versuchssk. Bd. 13, s. 243.) - Palm sugar examined by P. Horsin Deon (1879) yielded water 1:86, cane sugar 87:97, inverted sugar 9°65, other substances 0°50 per cent., and when dried 89-64 per cent. of cane sugar. The other organic substances consisted of 1-71 per cent. reduci ble sugar, 4-88 gum, and 3-06 mannite and fat. (Honig, Nahrungs-mittel?.) 3 The milk of ripe and unripe cocoanuts has been analysed by . L. L. — Slyke. The weight of milk from unripe nuts varied . from 230°5 to 383-7 grams, and in a ripe nut only 109°6 grams. PAIMZ 517 e composition of the unripe milk is an average of six Milk of unripe nuts. — Milk of ripe nuts. ay ater Bb GU". . sveecs. 95:00 91:23 Ash 617 1:06 Glucose 3973 trace. Cane sugar ....... éaset trace. 4°42 BEVIS oo. .scesveses 133 291 a 119 “145 = (Journ. Chem. Soc., June, 1891.) According to Hammerbacher, the fresh milk has the follow- 91-50 per cent. A AB: 5 Fat ee) Nitrogen free extractive ..scesesseee 6:78; -4; Ash icc 8 Oey | e milk had a sp. gr. of 1°0442. No fatty acids were present, perhaps, propionic. rae r the composition of cocoanut pearls, the reader is referred for 1888. ; ut oil has a peculiar and highly complex chemical on. Itis largely composed of the glyceride of laurie H**0?, and contains even lower homologues (¢.g. capric, caproic) capable of distillation in a current of open and to some extent soluble in water; but the glycerides stic, palmitic, and stearic acids are also present in » proportion. On the other hand, the low iodine absorp- rs that comparatively little olein or its homologues can ro ~In 1880-81 the foreign exports of cocoanut oil 1,888,122 gallons, valued at Rs. 20,90,797, Madras — 518 PALMA, alone having shipped to foreign countries 1,690,520 gallons, and sent in addition to other Indian ports 1,493,756 gallons. In 1886-87 the exports were 1,099,864 gallons, valued at Rs, 13,24,589, and the imports 556,562 gallons, valued at Rs. 7,54,515, The bulk of the exports (viz.,689,087 gallons) went to the United Kingdom. The imports were mainly from Ceylon (438,144 gallons), Bengal taking by far the largest proportion (viz., 350,437 gallons). Ifto these facts an abstract of the coasting traffic be added, some idea of the present position of the cocoanut oil trade may be had. The imports coastwise were in 1888, 167,486 gallons, valued at Rs. 2,05,60,067 ; the exports were 1,942,829 gallons, valued at Rs. 20,74,455. Of the imports, Bombay received 794,577, Burma 338,056, Bengal 131,463 gallons, and these quantities were almost entirely obtained from Madras. Cochin sent to Bombay 15,789 gal- lons, and to Madras 13,188 gallons. The other items to make up the total coastwise imports were unimportant. Local pro- duction added to these imports would constitute the supply from which the exports could be made, and in the case of Madras it is noteworthy that that Presidency imported practically no cocoanut oil, so that her exports to foreign countries and to other Indian ports were drawn exclusively from local supplies. With the exception of the small amounts obtained from Cochin, Bombay, &c., and some 6,000 gallons from Ceylon and other foreign countries, Madras imported no cocoanut oil. But she exported 1,754,701 gallons, of which 1,008,621 went to Bombay, 273,347 to Burma, 191,413 to Travancore, and 155,202 gallons to Bengal. But Bengal exported coastwise 8,648 and Bombay 3,454 gallons. The Bengal exports went to Burma, and the Bombay to Sind, Madras, Goa, Kattywar, &c. Adding the foreign exports to the coastwise exports and deduct- ing total of the imports, we learn that Madras exported in 1888, 3,425,221 gallons—an amount which may be viewed as the surplus over local consumption, Turning to Bengal and Bombay, a very different state of affairs is found to prevail—the Jnpor's exceed the exports, in Bengal by-313,009 gallons, and in Bombay by 1,125,572 gallons. An enormous trade in , q PALMA. 519 4 cocoanut oil is done in Cochin, as will be seen from the exports _ for six years :— a Europe. India, Burma, &c. Total Tons. me «1884-86 ........ pas oes 6,613 6,066 (12,679 2885-86 .ccdecccyee, see 3,494 7,237 10,731 OE... cys cativevs . 4,967 5,382 10,349 MIB OOG (155565005 seb 5a 6,300 6,048 12,348 BIO“ O8 oo. esas cutevees 6,193 7,778 13,968 BeP-U0 ©. ssc ccosssvee 4,048 8,264 12,312 id sent from one province of India to another. In 1886-87 imports were 125,222 cwts., valued at Rs. 11,76,799, the exports 9,337 cwts., valued at Rs. 79,836. The is come chiefly from Ceylon and the Straits Settle- ts, and are almost exclusively delivered in Bengal and y- The exports go mainly from Madras, the greater to Portugal, Persia, Russia, and Arabia, each receiving 300 to 500 cwts. Of the imports by far the larger por- S , 10, is the Palmyra palm of the English, and the Roudier ventails of the French. In Sanskrit it is called Téla, and the vernaculars T4l, Téd, Tér, and Panai-maram. The ies of the various parts of this noble palm are described detail in Sanskrit medical works. The root is considered to cooling and restorative ; the saccharine juice obtained from Spathe cooling and diuretic when fresh, but intoxicating fermented ; the pulp of the ripe fruit heavy and indiges- the gelatinous contents of the unripe seeds refreshing cooling ; the embryo of the germinating seed, and the bud of the tree, are used as vegetables, and are con- to be cooling, nutritive, and diuretic; the ash of the 8 given as a remedy for enlarged spleen. 520 PALMAE. The spirit distilled from the juice of this palm is similar to that obtained from the cocoa palm. The fine, brown, silky substance on the young petioles of the leaves of this and other palms is used as a styptic. B. flabelliformis yields an insoluble gum, like wniehnk: but of a darker colour. For an account of the economic uses of this palm, the reader is referred to the Dict. Econ. Prod. India, i., p. 495. Pheenix sylvestris, Rorb., Rheede, Hort. Mal. rit, tt. 22 to 25, Kharjura (Sans.), Kajiér (Hind., Beng.), Sendi (Mar.), Ishan-chedi (Zam.), also yields a juice, from which spirit is obtained. The fruit called Khcérik pounded and mixed with almonds, Quince seeds, Pistachio nuts, spices and sugar forms a Paushtik, or restorative remedy much in vogue. A paste formed of the seeds and the root of Achyranthes aspera is eaten with betel leaves as a remedy for ague. The juice of this palm is obtained by tapping the trunk. LODOICEA SEYCHELLARUM, Labill. Fig.—Bot. Mag., 2734-5-6-7-8. Sea Cocoanut (Zng-); Coco-de-mer (Fr.). Hab.—Seychelles, Vernacular.—Darya-ka-nériyal (Hind.), Kadat-rengay (Tam.), Samudrapu-tenkaya (Tel.), Katal-tenna (Mal.), Darya- nu-nadriyal (Guz.), Jahari-néral (Mar.), History, Uses, &c.—Prior to the discovery of the Seychelles Islands in 1743, the large and peculiar-shaped nut of this palm, found floating i in the Indian Ocean, was an object of curiosity which gave rise to many fabulous tales ; it was called Sea Cocoanut and Coco-de-mer by Europeans, Narjil- bahri by the Arabs, Narjil-i-daryai by the Persians, and important medicinal virtues were attributed to it. It is mow no longer valued by Europeans, but is still in great repute : among the Arabs and Indians as a tonic, aeigcly an 4 alexipharmic. Z 4 PALM, 521 ___ Rumphius gives a long account of this palm under the name of Cocos Maidivicus. The kernel is used in India in con- junction with Jignum colubrinum as a tonic, and a paste made of it in conjunction with the powdered horns of the Sambhar deer and the seeds of Strychnos Nux-vomica is applied to enlarged glands. 3 Description.—Thomas Moore, in the T'reasury of Botany, says: “This magnificent palm, which is found only in two small islands, Praslin and Curieuse, belonging to the Seychelles group, requires a great length of time to arrive at maturity. _ The shortest period before it puts forth its flower-buds is thirty years, and a hundred years elapse before it attains its full growth. From the age of 15 to 25 years it is in its greatest beauty, the leaves at this period being much longer than they are subsequently. The stem grows quite upright, straight as an iron pillar, and in the male trees frequently attains a hundred feet in height, the females being shorter. At the age of thirty, it first puts forth its blossoms, the males forming enormous catkins about three feet in length and three inches diameter, while the females are set upon a strong zigzag stalk, from which hang four or five, or sometimes as many a eleven nuts, averaging about 40 lbs. weight each. Fromthe _ of nearly ten years elapses, the full size, however, being attained in about four years, at which time it is soft and full of a Semi-transparent jelly-like substance. The apparently pecu- liar formation of the root portion of this tree attracted much _ attention a few years since, but upon comparison with other _ palms it seems to be explained as an extraordinary development _ of a common system. The base of the stem is rounded and fits into a natural bowl or socket, which is pierced with hundreds of small oval holes about the size ofa thimble, with oll - > on the outside, through which time of flowering to the maturation of the fruit, a period ck 599 PALM. bowl is of the same substance as the shell of the nut, only much thicker; it rots very slowly, for it has been found quite perfect and entire in every respect sixty years after the tree has been cut down.” The fruits are covered externally with a thick fibrous husk, and contain usually one, but sometimes two or even three immense nuts with hard thick black shells, each being divided half-way down into two lobes. The kernel is from three-quarters to one inch thick, and very hard and white, having much the consistence of vegetable ivory: it has no odour or taste; when soaked in water it softens a little, and can be split into thin fibrous bundles. Microscopie structure.—The kernel is composed of spindle- shaped cells having a central cavity, from which club-shaped canals extend to the cell-wall, where they are opposed to simi- lar canals belonging to a neighbouring cell. Commerce.—The nuts are an article of export from the Seychelles; hundreds of them may be seen at Port Victoria, Mahé, whither they are brought from the island of Praslin. Value in Bombay, Re. 1} per lb. for the dry kernel, Entire nuts fetch from Re. 1 to Rs, 2 each, according to their size. : ARECA CATECHU, Linn. Fig.—Roxb. Cor. Pi. i., t. 75; Bentl. and. Trim., t. 276. Areca palm (Eng.), Arec cultivé (fr.). ‘Hab.—Cochin-China, Malay Peninsula and Islands. Cul- tivated throughout tropical India. The seed. Vernacular.—Supéri ( Hind., Beng., Guz., Mar.), Kamugu, Pékku (Tam -), Péka-vakka, Vakka (Tel.), Adike (Can.), Adaka (Mal.). History, Uses, &c.—The betel -nut,in Sanskrit Guvika, Puga, and Kramuka, is a masticatory of great antiquity in the ‘ East. In the Panchadandachattraprabandha, Devaflamani, “ she who compels the gods,” goes to the court of king iis to play with him, dressed in a sky-blue robe, having 10 | hs PALM®, 593 hand and in her mouth a betel-nut wrapped in a leaf of the kalpa, one of the trees of Indra’s paradise, a fabulous tree, granting all desires. The betel-nut is symbolical of festivity, _ and isa phallic emblem. Vincenzo Maria da Santa Caterina in his Viaggio alle Indie Orientale says:—The Hindus adorn their idols with the nuts; if a woman wears them in her hair or on her neck it is a sign that she is public.” The nuts are dis- tributed along with sugar cakes at marriages (see cocoa-nut) ; _ when wrapped in the leaves of the Piper Betle or pan, along With lime and spices, they form the bira or vira, which is so much used by the natives of all parts of India, and is commonly _ presented by one to another in token of civility or affection. - They are also given in confirmation of a pledge, promise, or ea ral Pee es into the midst of an assembly, in token of an invitation to un- dertake some difficult affair; for instance, in the first story of the “Vetalapanchavinshati,” the king, when he sends the courtesan to seduce the penitent who was suspended from a tree nourishing himself with smoke, gives her a bira. Bira dena, ; Signifies “to dismiss” either in a courteous sense or otherwise. : A bira is sometimes the cover of a bribe, and a bira of seven leaves (sat pén ka bira) is sent by the father of the bride to the bridegroom places a viri or cigarette-shaped wira between the teeth, for the other party to partake of by biting off the dhe _ jecting half; one of the tricks played on such occasions 1s to _ Conceal a small piece of stick in this viri, so that the biting it _ In two is not an easy matter, The nut is also a constant offer- ing to the gods at Hindoo temples, and on grand occasions the ra is covered with gold or silver leaf. The betel-nut is mentioned in Chinese works written before Christian era under the name of Pin-lang, by some sup- to be a corruption of the Malay name Pinang; but 524 PALM. Bretschneider states (Chinese Recorder, 1871), on the authority of the Nang Fang Tsao mu chang, a work written in the 4th century, that the word is derived from Pin “a guest,” in allusion to the custom of presenting the nuts to guests which had been introduced into China from India, Karly Arabian writers mention the Fiéfal as the fruit of a certain palm, not of Arabia, hard as though it were wood. Their physicians describe it as good for hot and gross humors prepared as a liniment; and for inflammation of the eyes as a collyrium; and of great efficacy for drying up the seminal fluid, and as a digestive. Fiifal is a corruption of the Persian Papal, a word probably cognate with the Sanskrit Kuvara “astringent,” but said by some to be derived from the Hindi Kubar (gaz ) “ humpbacked.” Though the betel-nut must have been known to the Greeks who visited India, it does not appear to have been noticed by any of their historians or medical writers ; Desfontaines, how- ever, suggests that it may have been the Hestiatoris or Protomedia of Pliny (24, 102), so called from its promotion of gaiety and good fellowship at carousals, Hindu medical writers describe the unripe nuts as laxative and carminative, the fresh nuts as intoxicating and productive of giddiness ; when dried, they are said to sweeten the breath, strengthen the gums, remove bad tastes from the mouth, and produce a stimulant or exhilarant effect on the system. Their use 1s recommended in urinary disorders and as an aphrodisiac ; for the latter purpose a confection is made by boiling the nuts m milk and adding a number of aromatic and stimulant substances ; Sometimes Datura seeds and the leaves of Cannabis indica are added to this confection, when it is called Kamesvara modaka. Wnripe betel-nuts which have been boiled are known as red betel, or chikn} supari, and an extract which is obtained PALMA, 595 giddiness is well known in the East, and it has also been observed that the nuts of certain trees in most betel planta- tions retain their poisonous properties when dried. These trees cannot be distinguished from the others, so that not depen accidents happen from their nuts becoming mixed with t ‘produce of the plantation before their presence has ite d The poisonous properties are destroyed by heat, and consequently many people only use the cooked or red betel- nuts of commerce to avoid the possibility of accident. The only account of these poisonous nuts in European works appears to be that of Rumphius, which agrees in every respect with the particulars related by betel farmers whom we have - questioned upon this subject; it is as follows:—“Plurime etiam recentes sunt nuces, que qualitatem hanc habent, quod manducantes inebrient, ac vertiginosos reddunt uti Taba- cum illos afficit, qui ipsi not sunt adsueti; idem quoque, pris- tant vetustiores Pinange nuces, que novitianos adeo pectore oppressos, et auxios reddunt, ut strangulari videantur. Que proprie Pinanga-mabols seu Pinanga imebrians vocatur, (que a quibusdam pro diversa habentur specie) agra he dignoscuntur, si recentes transcissee in media cavitate ru sint. Observavi vero neutiquam diversam hanc esse speciem, sed varietatem atque degenerationem duarum memoratarum Specierum, que hinc inde in arboribus reperiuntur, quam vis arbores occurant, quarum cuncte nuces hance habent malignitatem, ac presertim tertie speciei.? Rumphius adds _ that when these nuts have been eaten by mistake, salt or limejuice, or acid pickles are the best remedies. The above facts seem to indicate the return of a few plants to an original wild form now extinct, especially as the fresh nuts of the best trees produce similar effects in a less degree. _ In Europe betel-nuts have been used as an anthelmintic for ‘worm and as an astringent, and in practice reputation as a vermifuge is well established P to 1889 it was not known to which of its constituents 4 nut owed its extensive use in the East as a mastica 526 PALMA. Bombelon (Pharm Journ. [3], xvi., 838) was the first to announce that it contained a liquid volatile alkaloid, the properties and composition of which, however, he did not describe. As it seemed probable that the physiologically active constituent was to be looked for in this alkaloid, Herr Jahns was induced to investigate the subject more closely (Berichte, xxi., 3404). From his investigation it is clear that an alkaloid arecoline is the most active constituent of the nut. Its physiological action has been studied by Dr. Maumé of Gottingen (Pharm. Zeit., Feb. 9, 1889, p. 97), who used for this purpose the hydrobromide and the hydrochloride, of which subcutaneous or intravenous injections were made, or sometimes the solution was applied to the conjunctiva. It was found that full-grown rabbits died within a few minutes after the subcutaneous injection of 25 to 50 milligrams, but recovered after 10 milligrams. Cats succumbed after the administration similarly of 10 to 20 milligrams, only the course of the poisoning was somewhat more prolonged. Dogs, even small animals of 5 to 6 kilograms body-weight, although strongly poisoned by the subcutaneous injection of 50 to 55 milligrams, were not always killed. The symptoms of poisoning which were observed corre- sponded in many respects with those seen by Schmiedeberg in his investigation of muscarine, and further, when lethal doses were not used, they could be neutralized by means of atropine sulphate ; eventually, however, they presented characteristic differences. The most dangerous action of arecoline consists in the slowing of the heart’s action by small doses, or even its stoppage, just as takes place with muscarine; but the latter works in smaller doses, and it is only after somewhat larger doses of arecoline that the ventricle of the frog stops in diastole, or is so influenced that it is not emptied, and only after long intervals makes a weak undulatory muscular contraction. Subsequent injection of atropine removes this action upon the heart. Simultaneously with the heart’s action the respiration. is also affected. Small doses cause a considerable increase the number of inspirations ; larger doses cause a slower action ign PALMAi, gee _ with intensified expiration ; and very large doses rapidly stop the breathing, especially in cats. After introvenous injection of a lethal dose the respiration usually ceases before the action of the heart. The subcutaneous injection of 50 to 70 milligrams of arecoline salts into dogs of 4 to 5 kilograms body-weight, besides strong irritation of the heart, gives rise to tetanic ‘cramps, which quickly give place to a partial paralysis. As a rule, however, the animals overcome the effects of such doses, the heart resuming its action completely as the effects pass off, but it becomes again affected through vomiting and liquid evacuations in which sometimes also worms are brought away. An increased peristaltic action of the bowels is, how- ever, provoked in rabbits, dogs, and cats by much smaller Intense poisoning of dogs, rabbits, and cats with arecoline y also be accompanied with so strong a contraction of the ils of both eyes, that in dogs and rabbits they do not show ger than the head of a good-sized pin, whilst in cats they re reduced to a mere streak. Instillation of arecoline solution a an eye gives rise also to a strong one-sided narrowing of the Pupil, but the quantity required is so large that the product f myosis in one eye may induce a flow of saliva im rabbits, and affect the heart and respiration in eats. For this reason - action of arecoline upon the human iris has not yet been It is in accord with observations made during the experi- ments on animals that the organism may become on n 528 PALM. is a natural constituent of the brain-substance, and arecaine comes near to the trigonelline of fenugreek. (Pharm. Journ., Feb. 23, 1889.) Description—The betel-nut has the shape of a very short, rounded cone, scarcely an inch in height; it is depressed at the centre of the base. The testa, which seems to be par- tially adherent to the endocarp, is obscurely defined, and inseparable from the nucleus. Its surface is marked with a network of veins, running chiefly from the hilum; these veins extend into the white albumen, giving the seed a strong resem- blance to a nutmeg. The small conical embryo is situated at the base. The ripe nut is feebly astringent. Caustic lye turns the brown portion red. Chemical composition.—The nut contains about 15 per cent. _of tannin substance, and 14 per cent. of fat, colouring matter, &c. (Pharmacographia.) .In the preparation of the bases Herr Jahns adopted two methods, which gave equally good results. According to one, the powdered seeds were exhausted three times with cold water, to which strong sulphuric acid had been added in the proportion of two grams to each kilogram of the seeds; the pressed and filtered extracts were evaporated to about the weight of the raw material used, and after cooling and again filtering precipitated with potassium-bismuth iodide and sulphuric acid. An excess of the precipitant had to be avoided, since it exercises a solvent action on the separated double salt. The red crystalline precipitate was after some days filtered out, washed and decomposed by boiling with barium carbonate and Water’; the alkaloids went completely into solution, whilst bismuth oxyiodide, colouring matter, &c., remained undis- solved. After filtration the alkaloidal solution was evaporated to a small volume, treated with sufficient caustic baryta, and shaken Tepeatedly with ether, which removed a base that has been. named “arecoline,” on account of its oil-like character. The residual liquid, which, beside alkaloidal hydriodides, con- tained some barium iodide, was neutralized with sulphuric acid, _ and the alkaloids were set free by treatment successively with 4 PALME. 599 silver sulphate, caustic baryta and carbonic acid. The solution _ of the pure alkaloids was evaporated to dryness and the residue exhausted with cold absolute alcohol (or chloroform), ‘Are= caine” remained undissolved, whilst a third alkaloid, together with colouring matter, &c., went into solution, and upon evaporation of the alcohol remained as an amorphous mass, According to the second method, the powdered areca nuts were exhausted cold with milk of lime, the filtered extracts The yield of arecoline amounted to 0:07, or at most 0°1 per cent., that of arecaine to 0°1 per cent., and that of arecaidine to Url per cent. _ Arecoline, C8H*™NO?, was withdrawn from the ether solu- he neutralized liquid evaporated to a small volume, and after ding sufficient potash solution again shaken out with ether. The base left upon evaporation of this solution was neutralized _ Arecoline forms a colourless oily liquid of strongly alkaline Teaction, which is soluble in all proportions in water, alcohol, ether, and chloroform. It is volatile and can be distilled, the boiling point being 209°C. The salts are easily soluble, Some of them deliquescent, but mostly erystallizable. It gives with | potassium-bismuth iodide a pomegranate-red precipitate, ¢ of microscopic crystals (a delicate reaction), and with molybdic acid a white precipitate. Potassium-mereury 530 PALM. of iodine throws down brown drops, and picric acid a resinous precipitate that afterwards crystallizes in needles. Gold chloride also throws down oily drops, which, however, do not solidify. Platinie chloride, mercuric chloride, and tannic acid give no precipitates. Arecaine (C’H"NO?-H°O), purified by repeated crystal- lizations from 60 per cent. alcohol, forms colourless crystals, permanent in the air, freely soluble in water and in dilute alcohol, less soluble in stronger and nearly insoluble in absolute aleohol, by which it is dehydrated. It is also insoluble in ether, chloroform, and benzol. The aqueous solution is neutral in reaction, and has a slightly perceptible weak saline taste. At 100°C. arecaine loses its water of crystallization, melts with frothing at 213°C., and carbonizes when more strongly heated. In a solution acidulated with sulphuric acid potassium-bismuth iodide produces an amorphous red precipitate that very quickly mes crystalline. Potassium-mercury iodide is far less delicate; it does not precipitate the (neutral) solution of the free alkaloid, but if this be acidified the double salt separates in yellow needles, or at first as an oily precipitate that quickly crystallizes. Potassium iodide also fails to affect a neutral solution, but upon acid being added dark-coloured needles separate. Phosphomolybdic acid, as well as tannic acid, give a slight turbidity; picric acid gives no precipitate, and gold chloride and platinie chloride precipitate crystalline double salts from solutions that are not too dilute. Arecaine combines with acids to form crystalline salts, having an acid reaction, freely soluble in water and less soluble in alco . Arecaidine, C’H"NO?H"0, isomeric with arecaine, forms colourless, permanent, tabular crystals, and is easily soluble in water and dilute alcohol, but almost insoluble in absolute alcohol, ether, chloroform, and benzol; it loses its water of ery- stallization at 100°C., and melts, attended with frothing, at 222-223°C.; it forms erystallizable salts and is precipitated by platinic and auric chlorides. Arecaine and arecaidine are PALM. | 531 easily separated by treatment with methyl-alcohol and hydro- 4 chloric acid, whereby arecaidine is converted into its — _ ester, arecoline, and arecaine into the hydrochloride. Herr Jahns (Berichte, xxiv., 2615) describes a fourth crys- talline alkaloid in areca nuts, to which he gives the name Guvacine, from gurdka, a Sanskrit name for the areca palm. Guvacine is less soluble in water or dilute alcohol than the er alkaloids, crystallizes in small shining crystals that at 265°C. and melt at 271-272° with decomposition. e crystals contain no water of crystallization, and upon . yield results corresponding to the formula C°H°NO*. the salts, the hydrochloride, sulphate, nitrate, platino- oride (CSH9NO?-HCl)*-PtCl*+4H*0, and auro-chloride, _ @H°NO*-HCl-AuCl’, have been prepared and crystallize It therefore appears that a series of bases occur in the nut, which, with the exception of choline, stand in near ation te each other— ; line C7H*NO?* Arecaine C7 H"“NO’+H’O Guvacine C°H9NO? Arecaidine C’7H**NO’?+ 8’O Arecoline C°H**NO? f ably other members of the series may be found by exa- uation of a larger quantity of material. (Pharm. Zigey 1891, 16; Pharm. Jowrn., Oct. 3, 1891.) Towicology. —Cases of poisoning from eating fresh Ga tats € poisonous nuts by mistake, not unfrequently occur, but have not heard of any fatal termination after such acci- The remedies used are acid pickles and copious draughts d water. The sufferers complain of great oppression in chest, with a sense of faintness and suffocation, sometimes by vomiting. According to Maumé, arecoline separates ed with Sey secretions and excretions, from which it — recovered, In the absence ofa characteristic colour arecoline separated from urine can only be identified ) by its behaviour with potassium-bismuth iodide, ologically by its action upon the heart of a curarized 532 PALMAE. Commerce.—Some idea of the consumption of betel-nut in India may be formed from the fact, that in addition to her own produce India imports about 30,500,000 pounds of the nut, value about 34 lakhs of rupees, from Ceylon, the Straits Settlements, and Sumatra. The exports are under 500,000 Ibs. which go to Eastern countries frequented by Indians, such as Zanzibar, Mauritius, Aden, China, &c. Bombay is the chief centre of the export trade. The coasting trade statistics show a total of about 44,000,000 Ibs., vaiue about 554 lakhs of rupees, passing from port to port. Bengal, Madras, and Goa are the chief producing provinces. The exports by land beyond the frontier are very trifling, about 1,000,000 lbs. going to Nepal and Bhutan. The varieties of the nut met with in trade are numerous; they may be classed as natural and artificial: the first class includes the different varieties of ripe betel-nut produced by cultivation which have not undergone any preparation ; the second class, all nuts, ripe or unripe, which have been treated by boiling or other processes before being offered for sale. CALAMUS DRACO, Willd. Fig.—Blume in Rumphia, it., tt, 131-182. Hab.—Indian Archipelago. The resin (Dragon’s blood). Vernacular.—It is known by the same names as the gum of Dracena Oinnabari (p. 504). History, Uses, &c.—The original Dragon’s blood of commerce was not derived from this plant. The older writers upon Eastern commerce speak of Dragon’s blood as an export to the East from Arabia and Socotra. Ibn Batuta, who visited Java and Sumatra between 1325 and 1349, makes no mention of this substance among the products of those islands. Barbosa, writing in 1514, speaks of Dragon’s blood as a product of but makes no mention of it amongst drugs found in — _ Malacca, Java, Sumatra, or Borneo. (Pharmacographia.) Rum- ___ Phius is the first who describes the mode of preparation followed “PALMA. 533 at Palembang to procure this drug. It appears that the resin exudes in abundance from the fruit, and, being very brittle, is easily detached by shaking and friction ; finally it is exposed to a heat sufficient to make it form a uniform mass. An inferior quality is said to be extracted from the crushed fruit by boiling. This drug is not mentioned by Indian writers on Materia _ Medica, but it is now frequently supplied by native druggists, q and their customers probably do not distinguish it from th genuine article. Description.—Lump Dragon’s blood only is imported into Bombay from the East: it occurs in large blocks of _ irregular form; it differs from Socotra Dragon’s blood in _ Containing remains of the fruit and numerous scales. Its fracture is somewhat porous, but in good samples the colour is nearly as brilliant as that of the drops from Socotra. _ Chemical composition —A very complete investigation of the _ properties of the various kinds of Dragon’s blood has been made by Messrs. Dobbie and Henderson. (Pharm. Journ., Noy. 10th, 1883.) They say: ‘Our results may be summed up as follows:—There are at least four distinct kinds in colour, melts at about 80°C., gives off red-coloured — highly irritating fumes when decomposed by heat, dissolves _ teadily with an orange-red colour in alcohol, ether, chloro- form, carbon bisulphide and benzene, is insoluble or only ightly soluble in cold caustic soda, ammonia, lime water and these reagents. Its alcoholic solution has an acid reaction and gives a brown-red coloured precipitate when mixed with a Solution of lead acetate. Its composition may be represented by the formula C'®H'20. This is undoubtedly the resin of | Calamus Draco, some of the specimens which were examined having their origin well authenticated. : “A second variety is of a beautiful carmine-red colour, melts: bo 100° C., gives off non-irritating fumes when decomposed. of red resin presently sold as Dragon’s blood, or labelled — ; ‘ in collections under that name. One variety is brick-red 534 PALM. by heat, dissolves freely with a pink colour in alcohol, ether and chloroform, but is insoluble in carbon bisulphide and benzene, dissolves readily in cold caustic soda, ammonia and sodium carbonate, and much more readily than the foregoing in lime water. Its alcoholic solution has an acid reaction and gives a lilac-coloured precipitate with lead acetate, Its com- position may be represented by the formula C'7H'90’, The source of this resin is quite uncertain. We have no means of determining whether it is identical with any hitherto described variety of red resin. The specimens examined are marked as having come from the Dutch East Indies, but beyond this we know nothing of their origin. ‘(A third variety is of a vermilion colour, melts about 80°C., gives off aromatic irritating fumes when decomposed by heat, dissolves with a blood-red colour in alcohol and ether, but is insoluble in chloroform, carbon bisulphide and benzene, dis- solves readily in cold caustic soda, ammonia, lime water and sudium carbonate. Its alcoholic solution has an acid reaction and gives with lead acetate a mauve-coloured precipitate. Its composition may be represented by the formula C'®H**0*. This is the resin from a species of Dracaena. One of the speci- mens examined is from Dracena Cinnabari, Socotra, and as it was gathered by Professor Balfour there can be no doubt as to its origin. Another specimen is from Dracaena Draco, and its origin is also well authenticated. The other specimens examined are marked some of them Calamus, but there can be little doubt that this is a mistake, and that all the resins having the properties just enumerated are derived from species of Dracena, It seems certain then that the resin derived from Dracena is totally different in property from that derived from Calamus. “The fourth variety is a mixture, in varying proportions, of s reddish-brown coloured resin, freely soluble in carbon bisulphide, and a light brick-red coloured resin, nearly insoluble in carbon bisulphide, The two portions also differ consi- derably as regards their solubility in ether, benzene, and other reagents, the dark portion being in all cases the less soluble of PANDANACEA. 26 535 of the two portions. The portion freely soluble in carbon Gisulpbide is probably identical with the resins of our first class, while the other portion seems to be a distinct resin. x é Mach discussion has taken place with regard to the nce of a volatile acid in Dragon’ s blood. It seems certain none of the varieties of this resin contain benzoic acid; at l events we failed to obtain an extract from any of them with etroleum: ether, in which benzoic acid is freely soluble. We 8 ted for cinnamic acid by sublimation, and found it present aa resins of the first and third classes, but not in those of e second and fourth classes. To ascertain the delicacy of ll quantities of such a mixture. Probably the error as to presence of benzoic acid arose through confounding it with namic acid, or possibly from working with a resin im benzoic acid had been formed by partial oxidation.” “ PANDANACE. ANDANUS ODORATISSIMUS, Linn. f. >.— Rorb. Cor. Pl. i., tt. 94—96. Screw Pine, Kaldera (Eng.), Pandan odoriferante (Fr.). ent Persia, Arabia. The stems, male inflorescence ‘ernacular —Keora (Hind.), Keya (Beng.), Kevada (Mar.), Guz.), Tazhan-chedi (Tam.), Mogali-chettu,. Gajangi ha, Kaita (Ma/.), Téle-mara, Kyadage-gida (Can.).. , Uses, &c.—The Ketaka or Dhéli-pushpike »” whose golden spikes of flowers are said to atone 536 PANDANACEZL. for all its defects, is a great favourite with Vishnu and Krishna, and its flower-leaves are much worn by women in their hair. The poets also celebrate its perfume. In the play of Malati and Madhava, the latter says :— The slowly rising breezes spread around The grateful fragrance of the Ketaka. A strophe quoted by Bohtlingk (Indische Spruche, 1., 2083) says :—The drunken bee mistakes the golden flowers of the Ketaka for a lotus, and blinded by ray rushes into the flower and leaves his wings behind him. In the Gita Govinda, the bracts are likened to a lance fit to pierce the hearts of lovers, and the opening buds of the Jasmine are supposed to be im- pregnated by its pollen, The defects of this plant are described as its crookedness, abundance of thorns (suchi-pushpa), and the desert places which it selects for a habitation. ‘Lhe Ketaka is obnoxious to Siva, and the following story is told to account for his hatred of the _ tree: Gambling with Parvati he is said to have lost every- thing he possessed, even to down the clothes upon his back. In a fit of repentance he wandered away and was lost, to his friends, who afterwards discovered that he had retired into a forest of Ketaka trees and had become an ascetic. Parvati, having assumed the form of a Bhil damsel with Ketaka in her hair, followed him into the forest, and having succeeded in making him break his vow afterwards upbraided him for incon- stancy ; whereupon he cursed the Ketaka and any one who should offer its flowers at his shrine. This episode is the sub- ject of a well-known Marathi Jaoni :~— Siva sathi jhali bhilina Jaga mohini Girja jhali udasa. Unhappy Girje, erst the world’s ador’d A gipsy maid now, seeks for Shiv her lord. According to the Nighantés, the plant has bitter, sweet, light, and pungent properties, and removes phlegmatic humors. In Persia it is called Kédi, Gulkiri, and Gul-i-kabadi; the — Arabs call it Kadi and Kadar. Rézi recommends it in leprosy PANDANACER. 537 d'small-pox ; it is corisidered by Mahometan physicians to be diacal, cephalic, and aphredisiacal. ‘They prepare a sharab boiling the pounded stems in water, also a distilled water the flowering tops and a perfumed oil. Mir Muhammad usain states that the Hindus believe that if these prepara- ms are used when smail-pox is prevalent, the disease will be erted, or be of so mild a form as to be free from danger. e ashes of the wood are said to promote the healing of mds, and the seeds to strengthen the heart and liver. India the perfumed oil is prepared by placing the floral s in sesamum oil and exposing it to the sun for forty days; 3 bracts are supplied and the old ones removed several during this period. This oil is much valued as a perfume, is used as a remedy for earache and suppuration of the s. The distilled water may be simple or compound; » latter case the bracts are distilled with rose-water or lalwood chips; it is used as a perfume and to flavour ts leaves of several species of Pandanus are used for famine times. ‘The edible species (P. edulis, Thonars), in Madagascar and the islands of the South Pacitie, not occur in India. The aerial roots of the different are much used to make coarse brushes in the East, n of the desired length being cut and the end beaten — fibres separate. Description.—The male inflorescence is a large, ter- pendulous, compound, leafy panicle, the leaves of which llowish-white, linear-oblong, pointed and concave, the s being armed with very fine sharp spines ; in the axil ch there is a single thyrse, composed of simple, small long, pointed, depending anthers, which are not raised from the rachis of these partial racemes by ts, The fruitiscompound, oval, from six to eight ter, and from six to ten long, weighing from pounds, rough, of a rich orange colour, composed 538 TY PHACEZ. of numerous, wedge-shaped, angular drupes; when ripe their large or exterior ends are detached from one another, and covered with a firm, orange-coloured skin; apices flat, consist- ing of as many angular, somewhat convex tubercles as there are cells in the drupe, each crowned with the withered stigma, internally the exterior half of these drupes next the apex con- sists of dry spongy cavities, their lower part, next the core or common receptacle, is yellow, consisting of a rich-looking, yel- low pulp, intermixed with strong fibres; here the nut is lodged. Nut of each drupe compound, turbinate, exceedingly hard, angular, containing as many cells as there are divisions in the apex of the drupe; each cell is perforated above and below. Seeds single, oblong, smooth, adhering lengthwise to a small fasicle of strong white fibres, which bese through the perfora- tions of the cell. (Rvaburgh.) TYPHACEA. Typha angustifolia, Linn., Eng. Bot. 1456. Vern.— Ramabina. The soft woolly inflorescence of the male spadix is applied like cotton to wounds and ulcers. The plant is abundant on the banks of the Indus, where it is called ‘Pun.’ From the pollen is made the Bir or Birata, much eaten by the natives of Sind. The Sanskrit name is aka, Description.—Perennial, culms straight, 6 to 10 feet high, round, smooth, jointed at the insertion of the leaves; leaves long, ensiform, obtuse, flat on the inside, as long of nearly as long as the stem, about 3 to 4 inches broad; sheath smooth, embracing the culms; male catkin 2 to 3 inches above the female, cylindric, 8 to 10 ae long, densely covered with stamens, and numerous 3 to 4 cleft fine filaments, each with 2 to 3 anthers; anthers linear; female catkin 8 to 10 inches 3 filaments. long; glume with fine Bir Sa ee ae AROIDEM. 539 AROIDEZ. ACORUS CALAMUS, Linn. Fig.—Bentl. and T'rim., t. 279; Rheede, Hort. Mal. vzi., t. 48. Sweet-Flag (Zng.), Acore vrai (Fr.). Hab.—Central Asia. Cultivated throughout India. The hizome. ’ Vernacular.—Bach, Gora-bach (Hind., Beng.), Vekhand, Gora-bach (Guz.), Vekhand, Bal-vekhand (Mar.), Vashambu (Tam,), Vasa (Tel.), Vashanpa (Mal.), Vajé (Can.). History, Uses, &c.—This plant bears the Sanskrit ames of Vaché “ talking,’ Shadgrantha “ six-knotted,” Ugra- _gandha “strong smelling,” Jatila “having entangled hair,” &c., and is described in the Nighantis as hot,pungent, bitter, stomachic and emetic; useful for clearing the voice by removing phlegm, and in colic. As an emetic it is administered in doses of about 80 grains with half a sér of tepid salt water; in dyspepsia it is given in combination with asafcetida, long pepper, black pepper, ginger, chebulic myrobalans, soncha/ salt, and the tubers of Aconitum heterophyllum, of all equal parts, in doses of half a drachm. As a stimulant or nervine it is used in combination With other remedies in low fevers, epilepsy, andinsanity. The authors of the Pharmacographia remark—‘The descriptions of Acoron, a plant of Colchis, Galatia, Pontus, and Crete, given by _ Dioscorides and Pliny, certainly refer to this drug.” The Arabian physicians also agree in identifying it with the _ Acoron of the Greeks, a name probably derived from the Persian Agar. Ibu Sina describes the drug under the name _ of Waj, and quotes Galen with regard to its properties, and all the Arabian and Persian physicians reproduce what Dioscorides has written concerning axépov, That this plant isnot the Calamus Gromaticus of the ancients appears to be evident, as Pliny describes both Acoron and Calamus aromaticus, The Arabians also do not identify the plant with Calamus aromaticus, but describe the latter under the name of Kasab-ed-darira and 540 AROIDER. identify it with Swertia Chirata. H4j4 Zein states that in his time (1368) Kasab-ed-darira came from Calicut, where it was called by the natives Béringa; if this statement is correct, the drug used by him must have been either Premna herbacea or Clerodendron serratum, the Bharinga of the Hindus. Royle supposes Calamus aromaticus to have been an Andropogon. Mahometan writers describe it as deobstruent and depurative, useful for the expulsion of the phlegmatic humours, which they suppose to be the cause of paralysis, dropsy, and many other diseases; they recommend it to be given to children to bite when teething, and prescribe it internally in calculous affec- tions. It has also a reputation as a diuretic, emmenagogue, and aphrodisiac, and is applied in the form of poultice to paralysed limbs and rheumatic swellings. A pessary composed of Acorus, saffron, and mare’s milk is used to promote delivery; a hip bath of the decoction is also said to be efficient for this purpose. Dr. Ondaatji, Colonial Surgeon of Ceylon, has brought to notice the use of sweet-flag as an anthelmintic in that island. He says: ‘“ An infusion of the thizome given to young children acts effectually, as I have seen many such cases treated among the natives.” Dr. Evers at the Seoni Main Dispensary has found the drug very effectual in dysentery. He uses the following decoction :—Bruised rhi- zome 2 ozs., Coriander } dr., Black pepper 3 dr., Water one pint. Boil down to 12 ounces, and let cool. Dose for an adult 1 ounce three times a day ; for a child 1 to 3 drachms, sweetened _ | with sugar, two or three times aday. He also remarks :—“ The decoction is not only useful in dysentery and diarrhea, but also in the bronchitic affections of children.” I have often taken it myself when suffering from a bad cold in the chest. (Ind. Med. Gazette, Feb. 1875.) | ‘The evidence collected by Dr. Watt for Dict. Econ. Prod. of India testifies % the value of Acorus as an aromatic bitter and stimulant, especially useful in allaying distressing cough. - oe Description.— The root-stock oecurs in somewhat tor-— . tuous, sub-eylindrieal or flattened pieces, of variable length; 10 AROIDEA. BAI he upper surface of these is attached the lower portion of the leaves which have been cut off; on the under surface may be seen a zigzag line of little elevated dot-like rings, the scars of roots. The root-stock is usually rough and shrunken, varying ncolour from dark-brown to orange-brown, breaking easily with a short corky fracture, and exhibiting a whitish spongy interior. The odour is aromatic and agreeable; the taste itterish and pungent. The Persian variety of Acorus is arker in colour when fractured and has a more powerful odour, the leaves have been entirely removed, instead of being ut off short. Microscopie structure——A section of the rhizome is like an of small empty cells. The vascular bundles are numerous, pecially just within the line of small cells just noticed ; each dle consists of a ring of spiral vessels surrounding a number Chemical composition.—The authors of Pharmacographia ty:—“ The dried rhizome yielded us-1°3 per cent. of a yel- Wish neutral essential oil of agreeable odour, which in a umn of 50 mm. long deviates the ray of polarized light 3'8° to the right. By working ona large scale, Messrs. Schim- &Co., of Leipzig, obtained 2°4 to 2°6 per cent. According » Kurbatow (1873), this oil contains a hydrocarbon, C™H", oiling at 159° C., and forming a crystalline compound with Hcl, and another hydrocarbon boiling at 955—258° C., Hording no crystallizable hydrochloric compound. By sub- utting the oil to fractional distillation, we noticed, above 250°, blue portion, which may be decolourized by sodium. The te oil acquires a dark-brownish colour on addition of per- oride of iron, but is not at all soluble in concentrated potash n : ‘Ae bitter principle, Nimes was isolated by Faust in 1867 ‘ ui-fluid, brownish glucoside, containing nitrogen, soluble 542 AROIDEA. both in ether and in alcohol, but neither in benzol nor in water. In order to obtain this substance, we precipitated the decoction of 10 lbs. of the drug by means of tannic acid, and followed the method commonly practised in the preparation of bitter principles. By finally exhausting the residue with chloroform, we succeeded in obtaining a very bitter, perfectly crystalline body, but in so minute a quantity that we were unable to investigate its nature.’ (Op. cit., 2nd Ed, p- 678.) ; Herr Thoms (Archiv. der Pharm. [8] xxiv., p. 465) announced the absence of nitrogen in acorin, which is contrary to the results obtained by Faust; at the same time this author states that under the influence of acids and alkalies, or of emulsin, acorin splits up into sugar and carburet of hydrogen, and that it readily oxidizes and is converted into a resinous substance acoretin, which, when reduced from alkaline solution by nascent hydrogen, gives an essential oil and sugar as final products, The fact of a glucoside behaving in this way being inadmis- sible has led M. Geuther to make a fresh examination of acorin, which he obtained by exhausting the root with cold water and separating the acorin by means of animal charcoal ; the impure acorin was then removed from the charcoal by means of alcohol, and, after purification, was found to contain 32 p.c, of nitrogen, 70°0 of carbon, and 9-1 of hydrogen- Treated with a boiling dilute solution of soda it yielded no sugar, but was converted into an acid substance which strongly reddened litmus ; treatment with dilute acids also yielded no sugar. Exhausted by soda, the bitter matter has the formula C*H"NO™, and the acid which has been yielded to the alkali has the formula C**H**O°: treated with hydrochloric acid it sets free an acid of the formula C?*H*°0* or C?*H*°0*, which appears to be a product of the oxidation of the free acid already noticed. M.Geuther considers that the acoretin of a is nothing butimpure acorin. (AnnalenderChem., — Herr Thoms | ecxl., p. 92.) AROIDER. BAS SCINDAPSUS OFFICINALIS, Schott. Fig.— Wight, Icon., t. 781. Hab.—Bengal. The fruit. Vernacular. —Gaj-pipli, Bari-pipli ( Hind.) , Gaja-pipal ( Beng.), Atti-tippili (Zam., Mai.), Enuga-pippallu (Ze/.), Dodda-hipalli (Can.), Thora-pimpali (Mar.), Motho-pimpali (Guz.). History, Uses, &c.—The ripe fruit of this plant is the e Gaja-pippali of the Nighantds; it also bears the Sanskrit names of Kari-pippali, Kapi-valli, Kota-valli, Shreyasi, and ‘Vashira. It is described as aromatic, carminative, stimulant, d useful in diarrhea, asthma, and other affections supposed be caused by deranged phlegm. In practice it is generally used as an adjunct to other medicines. S. officinalis is cultivated Bengal, chiefly in the Midnapore district, and the fruits, cut to transverse pieces and dried, form the Gaja-pipal of the Tuggists of Eastern and Southern India. In Northern and Western India an entirely different drug is Sold under the same name; it consists of the entire plant of 4 Balanophora often remaining attached to a small piece of the ‘dead stick upon which it grew. The largest of these plants 4re about five inches in length, and consist of a kind of cellular up, from which springs a scaly spadix surmounted by a glan- dular-shaped club of imperfect flowers, beneath which the stem 48marked by little pits showing the places where the female flowers were attached. This drug is mucilaginous and astringent, is no doubt improperly substituted for the genuine article. Description —The fruit of 8. officinalis occurs in slices 8n inch or less in diameter and about } inch in thickness, of a ‘$teyish colour and almost inodorous. The slices consist of a Central core surrounded by the seeds partly enclosed in the dried Pulp of the arils; when soaked in water they swell up and “ven, and the core may be seen to contain numerous large liber ls very sharply pointed at both ends which act like stinging urs. The pulp surrounding the seeds is full of needle-like of oxalate of lime, similar to those found in the acrid 544 AROIDE A. corms of other aroids. The seeds are rather larger than hemp seeds, kidney-shaped, grey and polished ; they contain a white oily kernel. Chemical composition.—With the exception of a minute trace of an alkaloid, nothing of special interest was detected. The mucilage afforded jelly-like precipitates with plumbic acetate and ferric chloride. No tannin was present. Ash, 14*6 per cent. Scindapsus pertusus, Schott., Rheede, Hort. Mal. wxii., é#. 20, 21, is a large perennial plant, running over trees and rooting on them like Ivy; leaves alternate, resembling those of the Pipal ( Ficus religiosa) but larger, often perforated and cutin the margins; spadices shortly-peduncled ; spathe gibbous, acute, a little longer than the spadix; spadix cylindric-obtuse. The juice of the plant with black pepper is given to people who have been bitten by the Kusriya Ghanas,* a snake so called because the part bitten by it mortifies. The juice, with that of the roots of Croton oblongifolium and of the fruit of Momordica Charantia, is also applied to the bitten part. ALOCASIA INDICA, Stiott. Fig.— Wight Ic., t. 794. Hab.—India, cultivated in Bengal and elsewhere. The — root-stock, Vernacular,— Ménkand, Kachu (Hind.), Mén-kachu (Beng.)? : Kas-alu (Mar.). History, Uses, &c.—This large Arum is the Ménaka — of Sanskrit writers ; its root-stock is a valuable and important — article of diet in Bengal, and often grows to an immense size, — being from six to eight feet in length, and as thick as a man’s © leg. When dried it can be kept for a considerable time and j affords a large supply of starchy food. In Western India it is — iv as an ornamental plant in gardens, but is — much cultivated ; little known as an article of diet; the acrid juice of t petioles is, however, much used as a common domestic remedy -. * Daboia Russellii, wxipels icigxn a ee : AROIDEE. BAB account of its styptic and astringent properties, The etiole is slightly roasted and the juice expressed, We ve seen purulent discharge from the ears in children ‘opped by a single applicaltag The tubers chopped fine, tied in a cloth and heated, are used as a fomentation in eumatism. Medicinally ménaka is said to be useful in anasarca, in hich disease it is used in the following manner. Take of the 1 of the root-stock eight tolds, rice-meal sixteen tolds, ater and milk forty-eight tolas each; boil them together till water has evaporated. ‘This preparation is called Médna- anda, and is given as an article of diet to the patient, nothing Ise being fees during its administration except milk. akradatta.) S$ a vegetable, the root-stock is peeled, cut in small pieces nd well boiled to remove its acridity; it is then mixed with er vegetables and cooked with the usual condiments. tr. D. Basu (Diet. Leon. Prod. Ind.,i., 178) remarks—‘“T1 have ever used it solely as a medicine ; but as food taken frequently, Seems to act as a mild laxative and diuretic. In piles pad itual constipation it is useful.” Surgeon-Major R. 8. tt (idem) states that it is a very agreeable vegetable _ du n valescence of natives from bowel SR AB Se it is ligh ad nutritious and somewhat mucilaginous. The ash of the t-stocks mixed with honey is a papi remedy for uternally it is white, opaque, and starchy, and when fresh has 1 acrid odour which is lost on drying. Pulped and washed ee a large ore of pum a pe 546 AROIDE. AMORPHOPHALLUS CAMPANULATUS, Blume. Fig.—Roxb. Cor. Pl. iti., t. 272; Bot. Mag., t. 2812 ; Wight Te., 785. Hab.—lIndia. Much cultivated. The tubers. Vernacular.— Jimi-kand (Hind.), Ol (Beng.), Surana (Mar., Gus.), Suranu (Can.), Karunai-kizhangu (Tam.), Kanda-godda (Zel.), Karuna-kizhanna (Wal.). History, Uses, &c.—This arum occurs as a wild plant on the banks of streams and also in several cultivated forms. It is the Surana and Olla of Sanskrit writers, and among other synonyms bears that of Arsoghna or “destroyer of piles.” For medicinal use, Sarangadhara directs the tuber to be covered with a layer of earth, roasted in hot ashes, and administered with the addition of oil and salt. Several confections are also used, such asthe Laghwourana modaka, Vrihat surana modaka, &e.; these are made of the tubers of the plant with the addition of treacle, aromatics (ginger and pepper) and Plumbago root, and are given in doses of about 200 grains once a day in piles and dys- pepsia. The dried tubers of the wild plant, peeled and cut into segments, are sold in the shops under the name of Madan-mast. The segments are usually threaded upon a string, and are about as large as those of an orange, of a reddish-brown colour, shrunken and wrinkled, brittle and hard in dry weather; the surface ismammillated. When soaked in water they swell upand become very soft and friable, developing a sickly smell. A microscopic examination shows that the root is almost entirely composed of starch. Madan-mast has a mucilaginous taste, and is faintly bitter and acrid; it is supposed to have restorative powers, and is in much request ; it isfried in gh{ with spices and sugar. It is interesting to note that the tubers of the greater Dracontia (Diosc., ii., 155) were preserved by the Greeks in the same manner for medicinal use. The cultivated plant is largely used as a vegetable ; under cultivation it loses mae ps de om acridity and grows to an enormous size. AROIDED. 547 _ Synantherias sylvatica, Schott., is regarded by the Hindus asa kind of wild Surana, and, with the wild form of Amorpho- .. phallus campanulatus, bears the Sanskrit name of Vajra-kanda E “thunder-bolt.” The country-people use the crushed seed to eure toothache; a small quantity is placed in the hollow tooth _ and covered with cotton; it rapidly benumbs the nerve; they 4 also use it as an external application to bruises on account of _ its benumbing effect, Inthe Concan the seeds rubbed into @ _ paste with water are applied repeatedly to remove glandular enlargements. he fruit is yellow, about the shape and size of a grain of maize, closely set round the upper part of the spike, which is several feet in height, and as large as that of the plan- tain. The skin of the fruitis tough, the pulp scanty and yel- low; it encloses two seeds having the shape of a coffee bean, and placed with their flat surfaces in apposition. The testa of e seed is soft, greenish-brown externally, green internally ; when fresh, but rapidly becoming hard and dry when cut. The taste is intensely acrid, after a few seconds it causes a most painful burning of the tongue and lips, which lasts for a long time, causing much salivation and subsequent numbness. A Section of the fruit and seed show the following structure from Without inwards :—lst¢, several rows of thick-walled cells, having Yellowish-brown granular contents (skin); 2nd, a parenchyma composed of thin-walled cells, having no solid contents except Needle-shaped crystals (pulp); 3rd, several rows of small cells containing chlorophyll (testa of seed); 4th, a delicate paren- chyma, the cells of which are loaded with very small starch Sranules, mostly round, some truncated. The tubers of Sanromatum pedatum, Schott., are very acrid, and are used externally under the names of Bhasamkand and Létas a stimulating poultice. The plant is extremely common, and its pedate leaves appear with the first rain in June. The flower, which is produced just before the rains, seldom attracts » being more or less buried in thesoil. The tubers are out as large as small potatoes, and of the same shape as those gies __Lagenandra toxicaria, Dalz., Ricede, Hort. ne 523, is a Ache g , a Riad Tok $$ : as ee 548 AROIDEZ. CRYPTOCORYNE SPIRALIS, Fisch. Fig.— Wight Icon., t. 778. Hab,.—Marshy banks and standing water. Southern India. The rhizome. Vernacular.—Nattu-ati-vadayam (Zam.), Natti-ati-vasa el.). History, Uses, &c.—The Ati-vadayam of the Tamils is the Atis of Northern India, and is the tuber of Aconitum heterophyllum. The country Atis of the Madras Fresidency has for along time been undetermined, until in 1888 Mr. M. A. ‘Lawson was able to refer it to Oryptocoryne spiralis and a species of Lagenandra. Moodeen Sheriff says the root bears a strong resemblance externally to Ipecacuanha, and he has used it as a tonic and anti-periodic with children. It attracted attention a few years. ago through several packages of it I _ appearing in the London market as ‘‘ False Ipecacuanha.”? It is a well-known drug in Ceylon, where it is employed by the _ native doctors in decoctions in combination with other drugs as a remedy for infantile vomiting and cough, and in the ease of adults for abdominal complaints and fever. The Singhalese obtain the drug from India and value it at 4 annas per poun retail. a Description.—Leaves petioled, linear-lanceolate; spathe sessile, much shorter than leaves, twisted ; ovary 5-celled. The rhizome is about the thickness of a small quill, The drag ~ appears in broken pieces from 4 to 13 inch long, annulated, a grey or dark grey colour externally and white internally, inodorous and acrid in taste. E Th the Cryptocoryne the annulations are not so frequent, and the drug is more slender than in the Lagenandra. : _ Chemical composition.—The drug contains starch and numer- Se raphides, but no alkaloidal active principle has feet high, with a thick, AROIDEZ. — 549 fleshy rhizome, juicy and white, sending’ off numerous thick fleshy roots of a white colour. The leaves are on long petioles, oblong, obtuse, entire coriaceous, large; sheaths stipulary, opposite the leaf; scapes axillary, solitary, compressed; spathe onger than the scape, tubular at the base, attenuated into a long, slender apex; fruit compound, about 1 inch in diameter; seeds cylindric-oblong, minute, several in each cell, erect from the base. The plant is a native of Southern India, and is _ considered to be very poisonous. Rheede says of it:— _ “Balneum ex hac planta preparatum omnem corporis estum ‘a __ Rheede (xii., 9) states that the root of Remusatia vivipara, Méravara Tsjembu (Mal.), Rukh-alu (Mar.), is made into an ointment with turmeric and used as a remedy for itch, and _that the juice with cow’s urine is considered to be TACCA ASPERA, £ozb. - Hab.—tTropical India. The tubers. Vernacular.—V érshi-kand (Hind., Beng.), Dukar-kand 1d (Mary z.), Handi-gadde (Can.). History, Uses, &c.—This plant is the Vérdhi- anda Sikara-kanda of the Nighantas, so called from. its being a urite food of the wild boar. It is. described as sweet, ugestive, nourishing and tonic; useful in cachectic affections, *h as leprosy, &c. T. aspera, T. levis, and T. pinnatifida all ve tuberous roots, from which a starch resembling arrowroot be obtained, and all three plants are probably utilized by >» herbalists, see usually supply the coarsely prepared starch their custom eee ee —The root is an Se eioig curved tuber, of a ng size, with wiry fibres from its sides; externally of a rown or blackish colour, and internally of a pale yellow- tt has a pies nauseous taste. A full oe age of 550 AROIDEA. the plant, as well as of the two other species mentioned, will be be found in Roxburgh’s Flora Indica. PISTIA STRATIOTES, Linn. Fig.— Roxb. Cor. Pl. iii., t. 268; Rheede, Hort. Mal. 27., #. 82. Water soldier (Eng.). . Hab.—Tanks and ponds of India. The whole plant. Vernacular.—Jal-Kunbhi (Hind.), Gond4la, Shérval (Mar.), Agasatamaray (Zum.). History, Uses, &c.—Amongst the Sanskrit names of this plant we may notice Jalodbhuta, Jalasaya, Guccha-bodhra, and Paniya-prishthaja “born on the surface of water.” This aquatic plant is a native of Asia, America, and Africa; it is considered by the Hindus to be cooling and demulcent, and is prescribed in cases of dysuria in the quantity of about ten pagodas’ weight twice daily; the leaves are made into a poultice for the piles. (Ains/ie.) The ashes are applied to ringworm of the scalp, and in some parts of India are known as ‘ Pana salt.’ A notice of the plant will be found in Arabic and Persian medical works under its Greek name orpariorns, Description.—Often found floating on stagnant pools, leaves sub-rotund, obcordate, rosulate, waved on the margins, the nerves spreading like a fan, uniting into a truncate are at the base; spadices axillary, solitary, seated on a short scape. Chemical composition.—The plant and salt have been examined — by Warden of Calcutta, who reports that the weed dried at 130°C. and carbonized yielded 31 per cent. of total ash, of which 6 percent. was soluble. The sample of “salt” was slightly deliquescent, alkaline in reaction, and had the appear- ance of dirty common salt. Dried at 130° it yielded 78 per cent. of potassic chloride, 22-6 per cent. of potassic sulphate, — DIOSCORINEA, 551 and minute quantities of potassic carbonate, sodic chloride, calcic sulphate, magnesic sulphate, and ferric, aluminic and icic oxides. Ae News, March 23, 1883, p. 133.) DIOSCORINE. This genus is of much importance as a source of food in ndia, and some of the species are used medicinally on account their acrid or bitter properties. In Sanskrit they bear the eral name of alu, and the different species are distinguished prefixes, ¢.g., Madhvalu “sweet yam” (Dioscorea aculeata), délu “globose yam” (D. globosa), Raktalu ‘‘red yam” purpurea), &c. But the Sanskrit name alu is also applied other plants having tuberous roots, and it is therefore it to say what the original meaning of the word may have n. Dioscorea builbifera in its wild state is extremely bitter ; ‘small potato-like tubers on the vine dried and powdered are das a medicinal application to sores, and are given inter- tion the plant loses its bitterness, and is much grown for bers which are roasted and eaten. triphyliai is very acrid, and its tubers are sometimes used laster to disperse swellings. We have received the tuber is yam from Burma, where it is used as a poison; when internally it causes great irritation in the mouth and omiting of blood, a sense of suffocation, drowsiness, and ion: and it is said that a piece of the tuber, the size of is sufficient to cause death in six hours. Nevertheless use it as an article of food after it has been cut in r p tedly washed, and steamed in an earthen pot. ame is — In Sanskrit the tuber bears | andy have a reputation as a remedy for piles: under : : — writers ; it is consi 502 CYPERACEA. - the name of Pashpoli “strangle cake.”” For an account of the economic uses of the different species of Dioscorea cultivated in India, we must. refer the reader to the Dict. Econ. Prod. of India, ii., p. 115. 3 The tubers yield a milky juice containing a small quantity of _ fat, a resin, and caoutchouc. Analysis of tubers—Water 60°722, Ash free from 0, CO,? and Si 02 0-895, Protein compounds 4°485, The following analyses of 1). alata and edulis are by Payen (Compt. rendus, xxv., 1847, and Moser, Landw.- Versuchsst. Bd., 20, 1877). Dioscorea alata. D. edulis. Water .. iseeas Wesvetiarses 10 O4 60°72 Ni Se matter”... i... 1:93 4°48 Pat. ..2: _ 0°35 Nitrogen free extractive ... 17:33 32°47 Cellulose .... Boi aa 1:09 Ash... eA SPIO 0:89 4 ' In dry substances. Nitrogen ..... Sc Eee 1:82 URPOORY OT at08 -s-.cs0c.s 0 .c5c 82°66 The nitrogen-free extractive of D. ae contained 4°79 per cent. canessngar, ‘18 per cent, cellulose, and 25°19 per cent. starch, CYPERACE A, CYPERUS ROTUNDUS, Linn. Fig.— Rotti. 28, #. 14, 7.2. ‘Hab.—Throughout India. The tubers. Vernacular.—Motha (Hind., Guz.), Korai (Tam.), Bhadra- muste, Tunga-muste (Zel.), Binibat Bérik-motha (Mar. » Mutha (Beng.). ~ istory, Uses, f— thin the Mustaka is 3 - rit red to be diusetic, diaphoretio, asta OYPERACEA. 5538 and stomachic, and is prescribed in febrile affections and derangements of the bowels. In Indian domestic medicine the fresh tubers are applied to the breast in the form of a paste as a galactagogue. C. rotundus is doubtless the o* (Suad) of Abu Hanifeh, who describes it as a certain kind of sweet-smelling root or rhizome (-<»,!), round, black, hard like a knot, which is an ingre- dient in perfumes and medicines. In the Kémiis it is said to possess a wonderful efficacy for healing uleers and sores. Ibn Sina says that the best kind of Suad is that which comes from Kufa in Chaldea, and that the Indian drug (C. scariosus) is said tomake the hair grow thin. He, along with other Arabian and Persian writers, describes the drug as attenuant, diuretic, em- menagogue, ‘lithontriptic, and diaphoretic; they prescribe it in febrile and dyspeptic affections, and in one ounce doses as an anthelmintic ; externally it is applied to ulcers, and used as an ingredient in warm plasters. Dioscorides calls it xtrepos and notices its use as a diuretic _ and emmenagogue and as an application to scorpion stings and ulcers; he also states that it is an ingredient in warm q plasters. Herodotus (4, 71) notices it as an aromatic plant used by the Scythians for embalming. «*epov is mentioned in the _ Iliad (21, 351) and Odyssey (4, 603) and by Theophrastus in his fourth book ; it appears to have been a favourite food of horses. Pliny (21,18) calls it Juncus triangularis or angulosus ; it is also probably the Juncus of Celsus (3, 21), mentioned as an ingredient in a diuretic medicine for dropsy, although he calls it Juncus quadratus. Description.—Culms erect, 1—2 feet, triangular, with rounded angles; leaves radical; sheathing shorter than the culms; root tuberous, tubers often crowded together, size of filberts, brown or black externally, white internally, odour like _ that of Acorns; umbels terminal, compound ; involucre 3-leaved, wnequal ; spikes linear, sub-sessile. Often a troublesome weed in cultivated ground. 554 CYPERACE. CYPERUS SCARIOSUS, £&. Br. Fig —C. B. Clarke, Linn. Soc. Journ. xxi., 159. Hab.—Damp places in Bengal. The tubers. Vernacular.—Nagar-motha (Hind. Guz.), Na gar-mutha (Beng.), ,Lavila, Négar-motha (Mar.), Muttah-kéch (Zam), Kola-tunga-muste (Ze/.), Konnari (Can.). History, Uses, &c.—This plant produces the ‘aromatic tubers which have long been in use in Hindu medicine and perfumery under the Sanskrit name of Nagar-mustaka; they are considered ‘to have the same medicinal properties as those of C. rotundus. Arabian and Persian writers mention this Indian Cyperus, but consider it to be inferior to O. rotundus. In the Concan, Nagarmoth, Solanum indicum, Tinospora cordifolia, Ginger and Emblic myrobalans, of each 2 tolds, are powdered and divided into 5 parts, and one part taken daily in decoction with a little honey and long pepper as a febrifuge. Several other prescriptions of a similar nature are used in fever, and will be found in the Wanaushédi Prakasha. In dysentery, Nagarmoth, Mocharas, Lodhra, Daitiphul ( Woodfordia floribunda flowers), unripe Bael fruit, and the seeds of Holarrhena antidysenterica are ground with whey and molasses and given in 6 massa doses. In famine seasons Nigarmoth has proved a valuable resource to the peor. Description.—The ovoid tubers of this plant are developed upon a thin underground stem, and are simple or branched, generally about 2 inches long and 4 an inch in diameter; the external surface is marked by a number of annular ridges, and is , almost concealed by the remains of leaves; when these are removed, the colour of the tuber is a deep brown; @ few wiry rootlets arise from its under surface, and at. the lower end is a portion of the underground-stem. The substance of the tuber is hard and of a reddish colour; it is divided into a central and cortical portion, the latter being of a darker colour. The odour is strongly aromatic like Acorus, but somewhat terebinthinate. The plant is aquatic and grows in the Concan in pone s and CYPERACE. 555 ditches along with Scirpus subulatus, Vahl.; both. plants are called Lav4la in Marathi, a name which appears to be equiva- lent to the English Rush. ; Microscopic structure—The outermost layer of the cortical portion is composed of large bundles of reddish-brown stony _ cells, separated from one another by interspaces; within it are _ from 6 to 8 rows of very thick-walled, empty cells; next a tissue of thick-walled cells, most of them full of large starch granules, but some containing essential oil and probably resinous matter. _ The central portion of the tuber is separated from the cortical _ bya single row of small yellow stone cells; it is composed of thick-walled cells full of starch like those in the cortical por- 4 tion, but differs from it, inasmuch as many of the cells contain : red colouring matter. Large vascular bundles abound in the root, some of them are surrounded by a layer of stony cells. Commerce.—-Two kinds of N&garmoth are met with in this market— Surat and. Kattiawar; the first is heavier and more aromatic than the second. WValue—Surat, Rs. 2 per maund of _ 37% \lbs.; Kattiawar, Rs. 1}.. The Surat Négarmoth i is probably obtained from R4jputana, where the plant is common in tanks, Scirpus Kysoor, orb. Vern.—Kasiri (Hind.), Kachara (Bomb.). The tuberous root found in tanks, about the ‘size of a nutmeg, and of a black colour externally, has astringent Properties, and is given in diarrhea and vomiting. We have met with two other species of Cyperus, yielding edible tubers. The one, called “Thegi” in Guzrathi, is probably C. bulbosus. It grows in the sand on the coast of Kattiawar, and is used as a bread-stuff at all times, and was of much value in the last famine. The tubers are ovoid and Pointed, about 4 of an inch in length, horny and translucent, brittle when dry and farinaceous when powdered. The other is called “ Pudhya”’ in Marathi; it grows in salt rice-fields, and aati in the Southern Concan. The tubers are half an inch 2 ;more in length, surface brown, with the remains of sheaths arising from four transverse rings, she a and — within. 556 CYPERACE. The analyses of these tubers gave the following results :-— Thegi. Pudhya. Fat ‘73 “65 Sugar, &e. (spirit extract) ... 82 1-64 Gum and carbohydrates ...... 9°00 5°63 Albuminous matter ............ 6°68 8°68 Starch . 62:99 66°24 Fibre ...... 6°78 4°51 Ash. ;. 38:60 2°06 Moisture 10°40 10°53 The amount of nitrogen in the first was 1-07 per cent. and in the second 1-39 per cent. There were traces of an alkaloid in both tubers. KYLLINGIA MONOCEPHALA, Linn. Pig.—Rheede, Hort. Mal. wii., t, 53; Rumph. Amb. v., 8, J. 2; Rottl. Gr, 18, t. 4, 7. 4? KYLLINGIA TRICEPS, Lin». Fig.—Bheede, Hort, Mal. zii., t. 52. Hab.—Throughout the Peninsula of India. The roots- Vernacular.—Nirbisi (Hind.), Sveta-gothibi, Nirbishi ( Beng.), Mottenga, Pee-mottenga (Mal.), Musta (Mar.). History, Uses, &c.—These plants are the Nirvisha of Sanskrit medical writers, who describe them as antidotal to certain poisons. Rheede describes K. triceps and K. mono- cephala as having similar properties, and states that the former plant is called Coquinka by the Portuguese. In Malabar 2 decoction of the roots is used to relieve thirst in feversand . diabetes, and oil boiled on the roots to reliéve pruritus of the — skin. He also states that they distil an-oil fromthe roots, — which is of dark yellowish-green colour, pleasant odour and Pree) GRAMINEZ. 5B7 pungent taste, and which is used for the same purposes as the decoction and to promote the action of the liver. Irving states that K. monocephala is used at Ajmere as ap antidote like zedoary, and Roxburgh notices its use as an anti- dote in Benga These plants have the odour, and apparently all the qualities, of Cyperus rotundus. Be Lele ee aes Ne TR ee ae Oe el Lea SS oe OP a NS re se te : Bee i Peto = . ¥ BE co 5 Fai « Description.—The roots are creeping, those of K. triceps bear tubers. The culms are erect and triangular, leafy at the base. The leaves membranaceous, flat towards the apex, ciliated with minute bristles on the margin and keel. The flower-heads of K. monocephaia are solitary, globose, dense and white; whilst those of K. triceps consist of from 3 to 6 spikes, one of which is much larger than the rest. The involucres are 3 to 4 leaved, unequal, the longest leaf as long as the culm. 4 GRAMINEA. ANDROPOGON SCHC@E:NANTHUS, Linn _ -Fig.-—Royle, Iil., t.97; Trin. Sp. Gr. iii, t. 327. Rusa _ Sass, Ginger grass (Hng.), Schenanthe des Indes (Fr.). _ Hab.—Indian Peninsula, Western Ghauts, extending spar- _ ingly to the coast. The essential oil. __ Vernacular.—Sugandha rosé, Rus4, Gandhis, Gandhbel, Mir- chiya gandh (Hind., Gus.), Agiy4-ghés, Gandha-bena (Beng.), Sugandhirohisha, Rohishe-gavat (Mar.), Parimalada-ganjani (Can.), Sakanérd-pilla (Tam.). — Uses, &c.—This grass is the Bhustrina or Bhutrina « earth grass” of the Raja Nirghanta, and is also known as Rohisha in Sanskrit. Among the synonyms which bears, we may mention Gandha-khéda and Gandha-trina “ odorous grass,” Su-rasa “well flavoured,” and Su-gandha “haying an agreeable odour.” It is described as aromatic 4nd stimulant and useful in bilious and phlegmatic affections. 553 GRAMINER. Mahometan writers upon Indian Materia Medica confound A. Schenanthus with Iskhir (A. daniger), and Mir Muhammad Husain gives Rus as an Indian name for Izkhir; he also men- tions several other Indian names, such as Gandhis, Gandhbel, &ec., showing that he was well acquainted with Riisa grass. The author of the Tuhfat-el-muminin mentions a distilled water prepared from Izkhir, and also an oil made by macerating the grass in sweet oil exposed to the sun ; it is therefore probable that in his time (1669) the essential oil was not made from A. Schenanthus. The industry probably commenced in the 18th century whilst Khandesh was in a flourishing condition under its Mahometan rulers. A. Schenanthus was first brought to the notice of Europeans by General Martin, who collected the seeds in the Balaghat, during the war with Tippu Sultan, and cultivated the plant at Lucknow, whence he sent seeds to Roxburgh, in Calcutta, The first mention of the oil is by Maxwell in 1825 (Calcutta Med. Phys. Trans., i., p. 367) ; it was afterwards described by Forsyth, 1827 (Ibid., iii., p. 213). The A. Nardus of Ainslie, which he calls ginger or spice grass, is doubtless the same plant ; he notices its use in infusion as a stomachic, and states that an essential oil is prepared from it which is useful in rheumatism. Preparation of the oil.—The oil distillers in Khandesh call the grass Motiya, when the inflorescence is young and of a bluish- white colour ; after it has ripened and become red, it is called Sonfiya.* The oil obtained from it in the first condition has a more delicate odour than that obtained from the ripened. grass. The Motiya oil is usually mixed with the second kind, which by itself would not fetch a good price in the European market. The grass grows freely, though not.very widely, on open hill- sides in West Khandesh, especially in Akréni. ‘The original seat of the Manufacture was Pimpalner, but as the oil is in _ great demand, the manufacture has of late spread to Nandurbér, Shahada, and Taloda. The makers are Musalmans, who, at the *'We are indebted to Mr. A. Lucas, Assistant Collector, Khandesb, for = 4i ‘ie * = BAAS Ra SAULT RULAU UME ae GRAMINEM. (559 close of the rains, about September, when the grass is ripening, buy it from the Bhils, stack it, and set furnaces at the sides of brooks where wood and water are plentiful. A large pit, four feet long by two wide and two anda half deep, is dug, and a furnace (chula) prepared. On this furnace is placed a copper or iron caldron, large enough to hold from 30 to 50 pots of water. After pouring in some water, the caldron is filled to the brim with chopped grass, and a little more water is added. The mouth of the caldron is carefully closed with an iron or copper plate, made fast with wheat dough. From a hole in this lid, a bamboo tube, wrapped in a piece of cloth, plastered with the flour of Udid (Phaseolus Mungo, Linn., black var.), and bound with ropes, passes into a second closed caldron, sunk to the neck in running water. The steam from the grass is con- densed in the second caldron, which, when full, begins to shake. The tube is then skilfully removed, and the contents of the caldron poured into a third similar vessel and stirred. Then the oil begins to appear on the surface, and is slowly skimmed off. The distillate is returned with fresh grass to the still. In 1879-80 the number of stills was 197, producing about 71 cwts. of oil. More than 100 stills are worked in Nandurbér alone, and the increase of the manufacture is prevented only by the — scarcity of the grass, he oil is packed in skins, and sent on bullock back over the Kundaibéri Pass to Surat, and by Dhulia and Manmad to Bombay. We are assured by the Bombay dealers that all the oil of Commerce is more or less adulterated ; and a comparison of the Commercial article with some oil distilled by one of us supports this statement ; the adulteration is said to be practised by the distillers, who, we are informed, are regularly supplied with oil of turpentine from Bombay. 373 lbs. of grass received from - Khandesh and submitted to distillation under our own superin- tendence in Bombay yielded 1 lb. 5} ozs. of oil. Portions of is oil were mixed with oils of turpentine, groundnut, rape, and linseed ; with all three it formed a milky or turbid mixture, ee the two first, after standing for some days, became perfectly bright. We are informed that formerly it was the custom to 560 GRAMINE2. adulterate with groundnut oil, but that turpentine is now used, as it cannot be detected by the evaporation test. The use to which Rasa oil is put in Turkey, to which country it is principally exported, rid Egypt and the Red Sea ports, from Bombay, was first explained by Hanbury (NV. Repert. f. Pharm., vili., 365), and in Pharmacographia we find the following interesting statement :—“ No drug is more subject than attar of rose to adulteration, which is principally effected by the addition of the volatile oil of an Indian grass, Andropogon Schwnanthus, L. This oil, which is called in Turkish Zdris yaghi,* and also Entershah, and is more or less known to Europeans as Gera- nium oil, is imported into Turkey for this express purpose, and even submitted to a sort of purification before being used.¢ It was formerly added to the attar only in Constantinople, but now the mixing takes place at the seat of the manufacture. It is said that in many places the roses are absolutely sprinkled with it before being placed in the still.” -Description.—Root perennial, with long wiry fibres ; culms erect, from 3 to 6 feet high, often ramous, smooth, filled with a spongy pith ; leaves very long, tapering to a very fine point, smooth in every part, and of a soft delicate texture ; sheaths, shorter than the joints on full-grown plants, with a membrana- ceous stipulary process at the mouth ; panicles linear, subsecund ; spikelets paired, but with only three joints ; flowers also paired, one-awned, hermaphrodite and sessile, the other, awnless, male and pedicelled, the terminal florets are three, one hermaphrodite, sessile and awned, the other two male, pedicelled, and awnless, Hermaphrodite calyx one-flowered, two-valved, base girt with Wool, as is also the rachis and proper pedicels ; corol one-valved, “unrss, izris, pronounced idris by the Arabs, is a Persian word, and is explained in the Burhan as a kind of wild mallow which the Greeks call Juba weil itn glee! ea (shahmn-el-maraj). If a decoction of it er vinegar and oil is rubbed on the limbs i inst venomous bites. +* ‘4s perhaps Pavonia Missions cat peers aig tint belonging to the GRAMINEZE. 561 4 along black awn occupies the place of the other, which has _ two small filaments at its base; nectary two minute leaflets: embracing the germ laterally; stamens, pistil, and seed as in the genus. Male calyx as in the hermaphrodite; corol one-valved; nectary and stamens as in the hermaphrodite, no pistil. (Rorburgh.) The oil of A. Schenanthus distilled by one of us was dex- gyre, the ray being rotated 39° to the right by a column of 100 mm., and 78° by one of 200 mm. Some samples of the commercial oil rotated the ray about 13° to the right, and others had little or no effect upon it. The colour of the genuine oil was that of pale sherry; the commercial samples were more hly coloured. The odour at first resembles that of the rose, but there is a persistent and terebinthinate after-flavour which not agreeable. The taste is pungent and agreeable, approaching that of ginger. _ Chemical composition.—The oil of this grass, which has been named Geraniol (C!°H'8O), is an alcohol belonging to the Series C"H—*0. The two samples examined by F. W. Semmler (Ber. d. D. Chem. Ges., 23, 1098), which yielded 90° Per cent. of geraniol, must have been adulterated, as they turned @ ray of polarised light 20° to the left, whereas the genuine oil distilled by one of us was strongly dextrogyre. Geraniol, Which occurs also in Pelargonium Radula, Aiton, has a fragrant or of roses, and is miscible with alcohol and ether; the boiling point at 17 mm. pressure is 120°5—122%5, and the refraction 48°71. With calcium chloride at 50° it forms a crystalline compound (C!°H'80) Ca Cl’, decomposed by water and slowly oxidised by air. Potash-fusion forms isovaleric ) acid. Neutral aqueous K*M.0* forms acetic and isovaleric a acids, Even boiling baryta-water slowly forms isovaleric acid. Chromic acid mixture forms citral (Semmier). HNO® forms benzene, HOy, oxalic acid, and a resin, but no camphoric a. (Beilstein Chemie, iii., 265 : Watts’ Dict. Chem., 2nd Kid., P. 609 ; Ber, v. Schimmel & Co., April 1891, p. 37.) 1—71 562 GRAMINEZ, Commerce.—The official statistics only show the combined export of grass oils, and do not enable us to distinguish the different kinds. In 1888-89, 15,270 gallons of these oils, valued at Rs. 267,800, were exported. As we have already stated, the production of Rusa oil in Khandesh, the chief source of the supply, does not much exceed 70 cwts. yearly. The value of oil of good quality in Bombay is about Rs. 3 per Ib. It is exported in pots containing about 40 Ibs. each. ANDROPOGON LANIGER, Desf. Fig.—Trin. Ic. Gr., t.326, Squinanch (Eng.), Schenanthe officinal (F.). Hab.—-Northern India to Tibet, Arabia, North Africa. The plant. o Vernacular.—Limjak, Khavi, Usirbhéd (Hind.), Karankusa (Beng.), Pivala-véla (Mar.), Pilo-vlo (Guz.). _ History, Uses, &c.—This grass is described in the Nighantas under the Sanskrit name of Lémajjaka, with the synonyms Dirgha-mulaka “long-rooted,” Jalasdya “aquatic,” Sévya, Amrindla, Ishta-képatha, &e., as cooling, usefal in feyer, and tridosha or derangement of the three humors. It is parti- cularly mentioned by Arrian in his account of Alexander’s jout- ney through the Punjab and Sind, and was gathered in Lus by the Phenician followers of the army, who called it spikenard. Dioscorides (i.,16) describes it under the name of sxoies, and says that the best kind grows in Arabia, has an odour like roses when rubbed between the hands, and a pungent taste. It has carminative and stimulant properties, and is useful as aD emmenagogue. This latter use of the plant is noticed by Hip- pocrates in his treatise on the diseases of women (Lib. ii., See- 5). The same plant was known to the Romans as Schcenus oF Juncus odoratus, and was used to flavour wine (Cato, R. R. 105, 25113, 1. Col. 12, 20, 53), and from Plantus (Pen. 1, 2; 59) learn that it was used to prepare a perfume in fayour with Ss GRAMINEZ. 563 Roman meretrices whom he speaks of as Schenicule or Scheeno delibute. Scribonius Largus (Comp., 167) mentions Scheenus, te, Junci odorati flores, as an ingredient in a theriace used as an : tidote to snake-bites, and Pliny also mentions it (12, 48) in his chapter on the sweet-scented Calamus. We are of opinion “flower,” and which he calls the pith, is really the cottony ealyx of the plant which the Arabs call 459! ¢% (fukkah el idkhir) or the “ flower of the Idkhir,” and use as an hemostatic. ther Arabic names for A. laniger are Kilal-el-Mémén “ Ma- un’s toothpick,” * Tibn-el-makah “ Mecca grass,” and Tib-el- b “the Arab’s perfume.” In Persia it isknown as Gar- m because the onager or wild ass (Gir) is particularly fond it; he describes it as a grass, which, when chewed, has a 2 of cloves and mastich, and which is called by the Arabs bé-Hanffeh Ed-D{nawarf, author of the Book of Plants, the following description of the plant :—‘“It has a root ght stalks of the w¥° (Kaulén or papyrus plant), save at itis wider, and smaller in the q»*5 (ku’oub, internodal ces), and it has a fruit resembling the blooms of reeds, but slender, and smaller; it is ground, and is an ingredient Perfumes ; it grows in rugged and in smooth grounds ; but om does more than one grow in the same spot ; when it becomes white.” tod The Arabian and Persian physicians describe Idkhir as hot ddry, lithontriptic, diuretic, emmenagogue, and carminative ; Tecommend it to be boiled in wine as 4 diuretic; ground Paste it is said to be a good application to abdominal Ss; added to purgatives it is administered in rheu- the flowers (calyxes) are used as an hemostatic. They it with the Schenus of the Greeks. El Maman, son of Hardn-el-Rasbid, the celebrated Caliph. en in the ground, slender, pungent in odour, and is like the = . 564 GRAMINEA, In medieval Europe it was officinal under the names of Scheenanthus, Squinanthus, and Juncus odoratus, and was also known as Foenum vel stramen camelorum “camel’s hay or straw,’ from its being the principle food of camels in the deserts between Syria and Egypt. In Arabia, under the name of ghusil, the powdered grass is still used as a perfume for the bath. Description.—This grass is distinguished by its simple rhizome, short thick tuft of radical leaves, and lanigerous calyx. The odour is like that of oil of Rhodium ; the taste aromatic, bitter, and somewhat acrid. Chemical composition—From 56 lbs. of the dry grass purchased in the bazar we obtained the large yield of 8% ozs. of essential oil ; it had a specific gravity of -905 at 85° F., and rotated a ray of polarized light 8-0 degrees to the left in column 200 mm. long. The colour was that of pale sherry. According to Schimmel & Co., the essential oil reminds one of the odour of Elemi oil. Its sp, gr. is *915, the optical rotation +34° 88’. It boils between 170° and 250°, and contains phellandrene (Bericht von Schimmel § Co., April, 1892). ANDROPOGON CITRATUS, De. | Fig.— Wail. Pi. As, far, iii,, t. 280; Rheede, Hort. Mal. wit., t. 72, Lemon grass (Eng.), Chiendent-citron (Fr.). 4 Hab.—Eastern Archipelago? Cultivated throughout India. The herb and oil. Vernacular.—Agya-ghis, Agin-ghés (Hind.), Gandha-bena ? (Beng.), Hirva-chaha, Olen-chaha (Mar.), Lili-chahe, Nuili- chahe (Guz.), Vashana-pulla (Tam.), Nimma-gaddi, Chippa- gaddi {Te/.), Vasana-pulla, Sambhara-pulla (Ma/.), Purvali- hullu V4sane-hullu (Can.), Pengrima (Cing.). History, Uses, &c.—rhis® grass is not mentioned to euly in the 17th century as an established and well-known cultivated plant, and it is not improbable that Hindu colonists GRAMINEA. 565 returning from Java may have introduced it. The Hindus colonized that island in the 5th century, and in the 7th century there was much intercourse between the mother-country and the colony, In Java the grass is called Sireh; it was known to Rumphius and other early writers on the natural history of the East, and in 1717 an oil distilled from it in Amboyna was known as a curiosity. (Hphem. Nat. Curios., cent. v—vi.; Appendix 157, quoted in Pharmacographia.) Temon-grass oil is mentioned by Roxburgh in 1820 as being distilled in the Moluccas, and it was first aatiot ell into London about the year 1832, An infusion of the fresh herb is a favorite native remedy in India as a diaphoretic and stimulant in catarrh and febrile conditions, and also in the congestive and neuralgic forms of dysmenorrhea, The oil is used as a carminative and as an application in chronic rheumatism. The oil has been made official in the Pharmacopwia of India. Dr. Waring, in the appendix to this work, records a high testimony in its favour both as an external application in rheumatism and in other painful affections, and as a stimulant and diaphoretie internally. He states that amongst the half-castes of South India it is one of their most highly esteemed remedies in cholera, In infusion the leaves are often combined with tea, mint, or black pepper. The oil is distilled in rude stills at the et. base of the hills in Travancore, from Anjengo northwards. The grass is burnt at the end of the dry Weather. In Europe the oil is now a well-known article of commerce under the names of Lemon-grass oil, Oil of Verbena, and Indian Melissa oil, It is employed as an ingredient in perfumes, such as Eau de Cologne, and for scenting soaps, and also for adulterating the “true Verbena oil” obtained from Lippia citriodora in Spain. Description.—Root perennial, young propagating- Shoots issue from the axils of the leaves that surround a short, subligneous leaf-bearing culm. Culms from 5 to 7 feet high, erect, simple, smooth, about as thick as a goose- -quill. Leaves Many, near the root bifarious, few on the upper part of the culm, of a soft texture, pale-green colour, slightly scabrous on 566 GRAMINE, the margins, otherwise smooth ; from 3 to 4 feet long, including their sheaths, and about 2 of an inch broad. Floral leaves small. Panicle linear, a little bent to one side, composed of many fascicles of spikes that are both terminal and form the exterior axils. Spikes generally paired on a common peduncle, with a common boat-like spathe, or involucre at the division; each has also its proper pedicel, and both spathe-shaped. Rachis articulated, much waved, hairy. Flowers in pairs, one hermaphrodite and sessile, the other male and pedicelled; the last hermaphrodite flower of each spike has two males; below there is only one male, as the rachis occupies the space of the other. Hermaphrodite flowers sessile. Glume girt at the base with wool. Corol 2-valved, awnless. N. ectary, two, broad, short, wedge-formed, obliquely lobed, crenulated bodies embrace the insertion of the filaments and the forepart of the germ. Male flowers pedicelled, calyx, glumes as in the hermaphrodite ones. Corol 1-valved, awnless. N ectary as in _ the hermaphrodite, stamens three. This grass flowers in the rains, but’ rarely. Chemical composition.—The most interesting constituent of this oil is Citral, which has been examined by J. W. Semmler (Ber. d. Deutsch, Chem. Ges., 23, 3556, and 24, 203). This author found that the aldehyde C!°H'®O, obtained by the oxidation of geraniol with chromic acid mixture, is identical with the citral of oil of lemons. By further oxidation with argentic oxide he prepared Geranie acid, C!°H!®02, a limpid oil, and by treating citral with acid sulphate of potassium, Cymol was ormed, a molecule of water splitting off. Up to the present time citral has been found by Messrs. Schimmel & Co. in the following essential oils :— Lemon oil from Citrus Limonwn. Limetta oil » Oitrus Limetta. Mandarine oil , » Citrus Madurensis. reer grass oil 3, Andropogon citratus. Buealyptus oil » Eucalyptus Staigeriana. | ackhousia oil » Backhousia citriodora. pat fruit oil “* Tetranthera citrata. Ae GRAMINED. ey, Commerce.—The oil is largely exported from Singapore and Ceylon, where the grass is cultivated. The shipments from the Malabar Coast during the last four years were as follows :— 1887, 943 cases; 1888, 1,678 cases; 1889, 979 cases; 1890, 1,610 cases. The exports from Cochin have risen from 228 cases in 1884 to 2,387 cases in 1889 and 1,917 cases in 1890. A case contains 12 bottles of oil, and is priced at Rs, 183. A. bottle is guaranteed to hold 23 ounces of oil. ANDROPOGON NARDUS, Linn. - Pig.—Benti. and Trim., t. 297. Citronelle grass (Eng.). ~Hab.—Ceylon, Travancore, cultivated at Singapore. e essential oil. Vernacular.—Maana (Cing.). : History, Uses, &c.—This grass is considered by some otanists to be the wild form of A. citratus. Other grasses closely allied to it are A. Khasianus, Munro, growing in Silhet, nd A. distans, Nees, growing in the North-West Provinces and in parts of the Bombay Presidency, but no oil has ever been distilled from these species, nor do they appear to be used medicinally by the natives. ; _ A. Nardus is not mentioned in any Sanskrit medical work, nor do the Arabian and Persian medical writers notice it. It Owes the name JWVardus to its having been confounded with laniger, which was named »ép8os by the Greeks who invaded India. At the present time it is only known in Southern India and Ceylon, and the Hindi names which have been ascribed to it in the Dict. Econ. Prod. of India properly belong to Schenanthus or A, citratus. ‘a Description.—A large perennial herb, with a long slightly branched, partly aérial rhizome, reaching 4 inch in diameter, and strongly ringed with the closely-placed scars of leaf-sheaths, the remains of which persist on the upper m, and giving off numerous tough root fibres. Stem ing 6 feet or more high, erect, stout, cylindrical, solid, and shining, partially concealed by the leaf-sheaths, 568 GRAMINEZ. scarcely thickened at the nodes, which are approximated below, but widely separated above, flat or channelled on one side in the upper portion. Leaves very large and long, numerous, erect, lower ones sometimes reduced to their sheaths; sheaths thick and strong, about 6 inches long, closely but not entirely enveloping the stem, quite smooth, striate ; ligule short, brown, ' Jaciniate, scarious; blade about 2 feet long, linear, very much attenuated at the apex, tapering below, minutely denticulate with forward points on the edges, smooth on both surfaces, pale somewhat glaucous green, lighter beneath. Spikelets yery small, arranged in couples, one-stalked, containing one male flower, the other sessile, with one hermaphrodite and often one barren flower; the couples, to the number of 3 or 4, articulated on alternate sides of a short, flattened, jointed rachis clothed along the edges with long white silky hairs tufted beneath the spikelets, forming a short acute spike about $—#% inch long; the spikes arranged in pairs on a common slender stalk, at the bent basal node of which is a large, erect, acute, leafy, striate, orange-red, shining bract, scarious at the edges, which encloses the pairs of spikes before expansion ; the pairs of spikes very numerous, placed on the somewhat zic-zac, elongated, smooth, slender, erect, flattened branches of elongated panicles, which come off in clusters from the axils of the upper leaves, the whole forming a very large tufted, elongated somewhat drooping inflorescence, often 2 feet or more in length; glumes nearly equal, acuminate, mem- branous, smooth, purplish, boat-shaped, the lower one of the sessile spikelet flattened on the back against the rachis and with- out a mid-rib, those of the stalked spikelets with several parallel strong veins ; pales of the lower spikelet 2, or with a third representing a barren flower, very unequal, the lower very small, deeply bifid with twolong cusps, from between which comes off a long, slender, slightly kneed purple awn, about twice the length of the glumes, and projecting considerably beyond the _ spikelet, the upper much larger, acute but without an awn, = very delicate and membranous, without veins; in the flower of _ the upper spikelet there is but a ides membranous gai: a | GRAMINER. 569 from the flower, plumose, bright red-purple. Fruit not united with the pales. (Bentley and Trimen.) The oil is of a pale yellow lour when pure. Mr. J.C. Umney (Pharm. Journ., Ap. 11, 1891, p. 922) has shown that the green colour of the commer- cial oil is due to the presence of copper. According to Messrs, immel, the sp. gr. should not fall below +895 at 15°C. The is often adulterated with petroleum. Chemical composition. —E. Kremers (Proc. Am. Pharm, Assoc., 7, p. 562) found the oil to consist of an aldehyde (C’H"O), rpene (C*°H**), an isomer of borneol, named Citronellol, acetic and valeric acids. These two acids are said to be Dodge (Am. Chem. Journ., 1889, p. 456) cbtained some- different.results. The aldehyde, isolated from the oil by s of a concentrated solution of sodium bisulphite, accord- to Kremers i is C’H‘*0, while Dodge obtained results corre- mding to ©'°H'20, and names the compound citronellic e, By the action of P*0°, an oily product, probably a 7° C, was probably a terpene. The portion boiling ey ee citronellyl alcohol, C!°H2°O, the same as ned by the reduction. of citronellic Aldehyde, the acetyl tvatives of both havi like odour. ANDROPOGON ODORATUS, Lisboa. ig.—Journ. Bombay Nat. ae Soe. iw. » P- 188. 570 GRAMINEA, History, Uses, &c.—This grass is not, to our know- _ ledge, mentioned by Sanskrit writers, but is well known to the peasantry by the names given above, which signify “ physi- cian’s grass”’ and ‘‘ pungent grass.’’ A. odoratus was first observed by one of us in 1875 as a grass growing sparingly at Tanna, near Bombay, and used by the natives as acarminative in the bowel complaiats of children (Mat. Med. of Western India, 1st Ed., p. 693), In 1889 this grass was found growing abundantly at Lanowli on the Western Ghauts by Mrs, J. C. Lisboa, and was described and figured in the Journal of the Bombay Natural History Society. We have since distilled the grass and obtained from it an essential oil having at first an- odour recalling that of cassia and rosemary, but afterwards a _ strong persistent odour of oil of cassia. Messrs. Schimmel & Co. notice the odour of Pine needle oil in this sample, and find — the sp. gr. to be 945, ‘ _ Description.—Root as in A. Schenanthus. Culm erect, 3—5 ft. high, sometimes branching from the lower part, glabrous; nodes long-bearded. Leaves lanceolate, cordate at the base, acute or acuminate, with a few long hairs ; the lower eauline and radicle leaves long, the upper small, but their sheaths very long. Ligula small. Spikes numerous, erect, branched, pedicellate (the pedicel of the lower spikes longer), and congested at the end of a long peduncle without @ sheathing bract and forming an erect, dense, ovoid panicle. The rachis, pedicel, and the spikes covered with long silky hairs. Spikelets nearly two lines long, of a purple colour, the ‘Sessile and the pedicellate nearly similar; outer glume of the sessile spikelet rather thin, many-nerved, somewhat obtuse and covered with long silky hairs, with a pit in some spikelets of the same plant and absent in others ; second glume as long as the first or a little longer, but broader, thin, and keeled; — third glume thinner and hyaline; fourth glume, smaller or an ys = inch long, with a hermaphrodite flower at the end of the pedici oe of the pedicellate spikelet covered a or more “herves, not re GRAMT. NEG. 571 obtuse; second glume thinner, with three nerves, somewhat broader, but as long as the first ; third glume hyaline, smaller; fourth glume very small, hyaline or none ; no awn; at the top a of the pedicel three stamens not well formed and not as large as in the hermaphrodite flower. (J. C. Lisboa.) _ The yield of oil from the grass was equal to that obtained from A. Schenanthus; it had a deep sherry colour, “a specific gravity of ‘931 compared to an equal volume of water at 84° F., and a rotatory power of —22:75 in a column of 100 mm. or (a)D= —24°43. tah el ANDROPOGON MURICATUS, Retz. Fig.— Beauv. Agr., t. 22. Cuscus (Eng.), Vettivér ( Tam.), Chiendent des Indes (F*.). Hab.—Coromandel, Mysore, Bengal, Northern India. The roots. Vernacular.—Khas, Bala, Panni (Hind.), Khaskhas, Bend (Beng.), Vala, Varélu (Mar.), Vélo, Khaskhas (Gusz.), Vettivér (Zam.), Vattivéru (Tel.), Béladvéru (Can.). ra History, Uses, &c.—The root of this grass, which ‘is the only part of the plant having aromatic properties, described in the Nighantés under the name of Usira, and bears among other synonyms those of Virana, Véni-mulaka * having braided roots,” Sugandhi-mulaka ‘ having preet-ainstiang. roots,” Sita-mulaka “ having cool roots,” &c. It is considered to be cooling, refrigerant and stomachic, removing bile and phlegm, and useful to allay thirst in fever and inflammatory affections. An infusion is used, and it enters into the com- position of several cooling mixtures. Sir W. Jones suggests that it is the Mrindia mentioned in Kalidasa’s Sakuntala, but Sit neme: is‘ more commonly applied to the leaf-stalk of the _ Lotus than to the roots of this grass. All parts of the Lotus are ‘Tenowned for their cooling properties, and the use of the ater Lily for Sakuntala’s complaint appears to us to be more ical. In Vedic times the ancient Hindus were instructed 579 GRAMINER. to build their houses in a place where the Virana and Kusa were abundant, and on some copper-plate inscriptions dis- covered near Etawah, dated A.D. 1103 and 1174, this plant is mentioned as one of the articles upon which the kings of Kanauj - levied imports (Proc. As. Soc. Bengal, 1873, p. 161). Externally it is used in a variety of ways: a paste of the root is rubbed on the skin to relieve oppressive heat or burning of the body ; an aromatic cooling bath is prepared by adding to a tub of water the root in fine powder, together with the root of Pavonia odorata, red sandalwood and the wood of Prunus Puddum. The same ingredients are applied in the form of a thin paste to the skin. (Chakradatta.) All over India the roots are made into aromatic scented mats, hung in door-ways, and kept wet to cool and perfume the atmosphere during the hot season; they are also much used for ing fans, ornamental baskets, and other small articles. When distilled with water, the roots yield a fragrant cc which is used as a perfume and for flavouring sherbet. _ Mir Muhammad Husain, in the Vakhzan-el- Adwiya, describes khas as a kind of Izkhir used in. India, known as Izkhir-i-Jémi and called by the Persians Bikh-i-wé4la. European physicians in India have used the root as a diaphoretic, and Pereira (Mat. Med., ii., Pt. 1., p. 132) states that in 1831 it was used in Paris and Hamburg as a preservative against cholera, being hung up in rooms and burnt as a fumigatory. In 1837 it was recommended by Foy in rheumatism and gout. At the present time the root is distilled in Europe to obtain the oil, which commands a high price, being used in the composition of many favourite perfumes, as ‘ Mousseline des Indes,”’ ‘‘ Maréchal,” Bouquet du Roi,” &e. -Description.—4. muricatus has an erect compressed culm, 5 to 6 feet high, with smooth nodes and linear-narrow : sub-bifarious rigid elongated leaves ; the panicle is verticelled 5 _ the branches are very numerous, simple and spreading; the _ joints of the rachis are smooth; the glumes are minutely GRAMINEA. 573. ‘very numerous and spring from a rhizome, on the upper surface of which are leaf-buds. The entire root is of a yel- lowish-brown colour, and has a strong and persistent odour, somewhat like myrrh ; the taste is bitter and aromatic. Chemical composition.—Khaskas has been analysed by Viags quelin, who has obtained from it a resinous substance of a __ deep red-brown colour, having an acrid taste and an odour like myrrh ; a colouring matter soluble in water; a free acid; a Salt of lime; a considerable quantity of oxide of iron ; a large ‘quantity of woody matter. (Annales de Chimie, Ixxii., p. 302.) The oil is difficult to extract; this difficulty may be overcome by placing the roots in a steam-jacketted still with just suff- cient water to drench them, allowing to stand for a short time, 4 and then admitting steam at about 15 lbs. pressure into the a jacket, when a light oil will come over. A current of steam afterwards admitted into the still and raised to 25 lbs. pressure = will bring over the heavier portion of the oil. Piesse states the yield to be 10 ozs. per ewt. : a COIX LACRYMA, Linz. Fig.— Bot. Mag., t. 79; Rheede, Hort. Mal. wii., t. 70. _Job’s tears (Eng.), Larmes de Job (Fr.). de Hab.—Plains of India and warm hill-slopes Broa: the : Punjab to Burma. Cultivated on the hills. The seeds. Vernacular.—Sankhru, Sankhlu, Gargari-dhan (Hind.), Gargar, Kunch (Beng.), R4n-jondhala, Ran-makai (Mar.), Gus.). History, Uses, &c.—The different species of Coix bear the Sanskrit names of Gavidhuka, Gav edhu, and Gavedhuka. They are mentioned in Vedic literature, and appear to have been one of the cereals which were cultivated by the Arians on the hill-slopes of the Himalayas. They are = splat by the hill-tribes in the Khasia and Naga Hills in Assam. and. Burma, where they are known by the ular names ae wate Kalinsi, Kyeit, &e., and are — B74 - - GRAMINEZ:, used as a food-stuff. The wild form, common in the plains, is only used for medicinal purposes, and is considered to be strengthening and diuretic. The Arab travellers in the East became acquainted with the seeds and named them Damu Daud “David's tears,” and afterwards Damu Aytb “ Job’s tears.” Hs-Saghani, who died about the year 1260, mentions them in the Odd) as a well-known strengthening and diuretic medicine. The Arabs introduced the plant into the West, and it has become naturalized in Spain and Portugal, where it is still known as Lagrima de Job. European botanists have rather inappropriately given the name of Coix ( Greek xo¢) to this genus, Coix being the name of a kind of palm growing in Africa and mentioned by Theophrastus and Pliny. The following notice of C. lacryma occurs in the Descriptive Catalogue of the Vienna Exhibition, 1873 :—“< The seeds known as Job’s tears are used as food in China and Malacca, under the name of Eejin or Ee-yin. ‘It is,’ we are told, ‘the most remarkable among food-grains for its chemical composition.’ _ Dr. Smith writes that ‘it is larger and coarser than pearl- barleygbut it is equally good for making gruel. As it is sold for five pence per Chinese pound, it makes an excellent diet- drink for hospital patients in China.’ Dr. Hooker observes that ‘a great deal of Coix is cultivated in the Khasia Hills; the shell of the cultivated sort is soft and the kernel is sweet, __ Whereas the wild Coix is so hard that it cannot be broken by the teeth ; each plant branches two or three times from the base, and from seven to nine plants grow in each square yard of soil; the produce is small, not above 30 or 40 fold’ In Mason’s ‘ Burmah’ it is stated that a species of Coix, with large esculent seeds, which are parched like Indian corn, are often for sale in the bazars, and are cultivated very extensively by the Red Karens.” C. lacryma has also been introduced into Brazil, where it is cultivated to some extent. For much interesting information _ concerning the different species or varieties of the plant, and a the economic uses to which the seeds are put, we must re: GRAMINEH. — 575 Description.—The silicious involucre of this grass con- taining the seed is sold in the drug shops. It is about the size and has much the appearance of a small cowrie shell, shining white, and very hard. At the base is a scar marking the attachment of the peduncle; at the apex an opening, from which, even in the dry state, a portion of the female flower may be seen protruding. In the fresh state a spike of male flowers, from one to two inches long, rises from it. Chemical composition. —Church (Food Grains of India) found the edible grain, separated from the husk, to contain water } 13-2, albuminoids 18-7, starch 58°3, oil 5-2, fibre 15, ash 2:1 in 100 parts. Peckholt, who examined the seeds grown in Brazil, ascertained that 1000 parts afforded (among less im- portant constituents) fatty oil 6-6, resin 3, sugar 7, starch 84, husks and shell 696 parts. (Cat. of the Exhibition of 1866 at Rio de Janeiro.) ERAGROSTIS CYNOSUROIDES, fom. et Sch. Fig.— Delile, Descr. de ? Egypte, t. 10; Rheede, Hort. Mal. wu., t. 57. Hab.——Throughout the plains of India. The herb. Vernacular.—Kusa, Darbha (Hind.), Kusha (Beng. }, Kusha (Har.). History, Uses, &c.—In Hindu ritual the Kusa occupies much the same position as the Durva and Tulasi. Among the ‘Synonyms for this grass are Darbha, Barhis “that which is plucked up,” Suchy-agra “ needle-pointed,” Yajna-bhushana “ornament of sacrifice,’ Dirghapattra “ haying long leaves,” Vajna “ lightning,” Suchi-mukha ‘‘needle-mouthed,”’ Punya- trina “holy grass,” &c. Its pointed leaves are used for the purification of sacred ber erages, and spread beneath the Sacrificer and the sacrifice, like the Vervein was amongst the Romans, - In the Vedas this plant is often invoked as a god: “Thee, O Darbha, the learned proclaim a divinity not subject to age or death; thee they call the armour of Indra, the pre- Server of regions, the destroyer of enemies ; a gem that gives 28 el eS ae eee 576 GRAMINER. increase to the field; at the time when the ocean resounded, when the clouds murmured, and lightning flashed, then was Darbha produced, pure as a drop of fine gold” (Atharva Veda). The Vedic rituals furnished instructions for its use. According to Asyalayéna, two pieces without knots were used for purify- ing butter—one was to be held in each hand between the thumb and the fourth finger, the second and third fingers being raised. Turning towards the East, Savitri, Vasu, and the Sun’s Tays were invoked. At the new and full moon they fasted and tied together Kusa and firewood, hence the name Kusdkara for fire, the sacred fire being made upon a tuft of the grass. At the time of the first cutting of a child’s hair, the father took a position to the south of the mother, and, holding in his hand twenty-one blades of the grass (to represent the twenty-one _ Maruts or winds), invoked Vayu, the god of wind. The father, or, in his absence, a Brahmin, then took three blades of the grass aud thrust them, points foremost, into the child’s hair, saying, “O herb protect him.” The Vedic homestead was directed to be built in a place where the Kusa and Virana grew, its foundations were to be strewed with the grass, and all prickly herbs, as the Apamarga, the Saka, the Tilwaka, and the Parivyddha, were to be extirpated. When they learned the sacred books, students used to sit upon a spot of ground strewed with the Kusa, and on leaving they carried away, amongst other things, some blades of the grass as a remem- brance and good omen. In the Brahmanic period the Kusa was used in invoking Vishnu; anchorites covered their nakedness with the grass, or with the skins of animals and bark of certain trees. In modern times it is in constant requisition in Hindu ceremonial, and at funerals the chief mourner wears a ring of the grass upon his finger, and it is placed beneath the pindas. Brahmins place it in the hands of pilgrims when they bathe in the sacred Ganges. M. Sénart draws a comparison between the Vedic Kusa and the Beresman _ of the ancient Persians, and explains its significance in Buddhie : ritual : it serves as a sacred prayer-carpet which is p pside ae over by the divine Intelligence. As a medicine it enters into ps GRAMINEZ. 577 - compound prescriptions for dysentery and menorrhagia, and is Specially used as a diuretic. It is often confounded with —Cynodon dactylon by the herbalists, or perhaps they consider both grasses to be equally efficient. Description,—Root creeping, perennial. Culms straight, rigid, round, smooth, from 1 to 3 feet high. Leaves numerous, © very long, chiefly about the base of the culms, rigid margins hispid. Panicle erect, linear-oblong, often tending to a : eonictd form, composed of many somewhat threefold, verti- celled, horizontal, short, rigid, secund ramifications. Spikelets ‘many-flowered, depending, in two rows, from the under-side of 4 ‘the ramifications. Valves of corolla pointed, the inner ‘one rather the largest. CYNODON DACTYLON, Pers. _ Fig.—Zing. Bot. wii., t. 850; Fl. Grec.,t., t, 60. Creeping g’s-tooth-grass (£ng.). Hab.—Plains of India, westward to the south of England, e herb. Vernacular.— Durva, Déb, Hariydli (Hind.), Durba ( Beng.), harvé, Harala, Haryéli (Mar.). gs History, Uses, &c.—This grass must have first ttracted the attention of the ancient Hindus by its value as @ food for their cattle. A modern Indian proverb says— amindiri dab ki jar hai (an estate like the roots of the Dib, ie, is always bearing). The ~plant has many synonyms ™ anskrit, such as Granthi “ knotted,” Sveta ‘‘ white,” gavi “belonging to Sukra” (the regent of the _— 8), Ruha “‘ growing,” Dur-mara “ not easily dying,” &c. Shah thus apostrophizes himself :— Nanak! nannhé ho raho jaisi nannhi dab! Aur ghas jal jengi, dtib khiab ki khub. -Be modest Nanak ! as the fresh soft Dub doth lowly he, : Whilst other grasses scorched up are, the Dib’s bloom ne’er doth he Rig-Veda (x., 134) misfortunes are prayed to depart Diirva whose seeds fall far from the plant; an allusion -spreading habit of this grass, which has also given na 4 578 GRAMINES. rise to the proverbial expression ‘‘ Dib ki nal” (the sheath of the Dib) as applied to family connections, so called from their tendency to spread far and wide like the Dib. Like other useful plants this grass was deified by the Hindus; in the Atharva-Veda it is thus addressed— ‘“‘ May Dirva which rose from the water of life, which has a hundred roots and a hundred stems, efface a hundred of my sins, and prolong my existence on earth a hundred years.’ The Hindus believe that a benevolent Apsaras or nymph dwells in the plant, and when they build a house they place the grass on the four corners of the foundations. This practice dates from Vedic times. Dirva is also spoken of as Dirveshtaka, from its being used in erecting an altar; it is sacred to Vishnu and Ganesha, and a festival called the Dirvashtami is held in its honour on the eighth day of the light half of the month Bhadra; at this festival the male worshippers wear the grass tied to the right arm, and the females tied to the left. At marriages the right arm of the bridegroom is tied to the left arm of the bride with Dirva;it isa phallic emblem, like the /étu or straw was in Europe. In the third act of the Vikramorvasi of Kélidasa, Urvasi shows herself to Purdravas with her hair decked with Dirva, asymbol that she accepts his love. De Gubernatis says :—‘ A Pésaro, le jeune paysan, lorsqu’il désire demander en mariage la jeune fille qu’il aime, éte du pailler un fétu de paille et, en le lui montrant, lui demande si elle veut entrer danssa maison.” According to Asval4yana and Nérdyana, the husband, in the third month of his young wife’s pregnancy, should squeeze the juice of the Dirva into her right nostril to secure a male child; this practice is still customary in Western India and probably elsewhere. Dirva is one of the eight ingredients of the Arghya, a respectful oblation made to gods and venerable men. The popular version of the Ramayan mentions the eight ingredients in the following couplet :— ~ Dahi, Darba, rochan, phal mula . Nav tulsi dal, mangal milé, a ive, curdled milk, darba, rochan, flowers and roots, you leaves 7 OE cox Tulsi and Lotus, turme turmeric. | GRAMINE. 579 According to the Panchatantra, Dérva was born from the ___ hairs of a cow ; ina strophe quoted by Béhtlingk (Ind. Spr., s ii, 2921), the leaf is described as the ornament of the Dirva, ___ like the flower of the tree, independence the ornament of man, and the husband the ornament of the wife; happy are the _ gazelles who eat the Dirva, for they see not the face of rich fools. Darva is mentioned in the Nighantés; medicinally the fresh juice is considered astringent, and is used as a snuff in epistaxis. The bruised grass is a popular application to _ bleeding wounds. The Indo-Portuguese call it gramina, and use it as a substitute for Triticum repens, L., which is generally msidered to have been the @ypeors of the Greeks, and Gramen the Romans, though some authorities are of opinion that both T. repens and Cynodon Beate were used indiseriminately by the ancients, Description.—tThe roots are tough and creeping, almost _ Woody, with smooth fibres. Stems also creeping toa great ; extent, matted, round, jointed, leafy, very smooth. Leaves ering, sharp-pointed, ribbed, hairy, a little glaucous; with g§ striated smooth sheaths, and a hairy stipula, Flowering oe branches a span high, leaky; simple, terminating in 4 bs ve arly equal, crowded, erect, many-flowered linear spikes; the “ea stalk of each triangular, roughish ; flat and slightly ordered on one side, along which the nearly sessile, shining, lish flowers are ranged in two close alternate rows. The ais longer than the calyx, very much ae opposite am to the latter. ZEA MAYS, Ln. Fig.—Lam., Ii, t. 749; Bentl. and Trim., t. 296. Maize, Corn (Eng.), Mais, Blé ture (F*.)- b.—S. America and West Indian Islands. The War.— Makkii, Bhuta (Hind., Guz.), Janar (Beng.), Bonda (Mar.), Makka-sholom (Zam.). 580 GRAMINER. History, Uses, &c.—A wild form of this cereal is said to be still found in some of the West Indian Islands. The vernacular names point to its introduction into India from Mecea, but the Durah-i-Makka or Gandum-i-Makka of Mahometan writers on Materia Medica, which they also call Khanderis (xév8pos), is the Sorghum vulgare or Great millet, the Juar of Northern India, and the Sholam of Madras. . The Arabs call Zea Mays Durah kizén or Durah shém{. We learn from Chinese literature that it was cultivated in China in the 16th century, and was then traditionally asserted to have been an introduction from the west. On the Continent of Europe, it is best known as Turkish corn. It is now cultivated in all warm countries, and is considered by Mahometan physicians to have properties similar to those of Sorghum vulgare, viz., resolvent, astringent, and very nourishing ; they consider it to be a suitable diet in consumption and a relaxed condition of the bowels. In Europe it is much used asa valuable article of diet for invalids and children under the names of Polenta (Maize meal) and Maizena (Maize flour). In Greece the silky stigmata are used in decoction in diseases of the bladder, and have lately attracted attention in America under the name of Corn silk, of which a liguid extract is sold in the shops as a remedy in irritable conditions of the bladder with turbid and irritating urine; it hasa marked diuretic action. The meal has been long in use in America as a poultice, and gruel is also made of it. In the Concan an alkaline solution is prepared from the burnt cobs and is given in lithiasis. _ In the United States for starch manufacture from maize it © has been found desirable to get rid of the oily embryo—this is done by machinery. The embryo is too rich for feeding stock unless the oil is removed—this is done in the hydraulie press, and the cake when ground into meal is very valuable as a food. for stock. ‘The oil promises to be useful for medicinal pur . instead of olive oil. In the unrefined state it has Specific gravity of 916 at 15°C, the elaidin test shows the — = Presence of a large quantity of olein. Maize: oil seats GRAMINEZ, 581 yellowish-brown colour, with an odour and taste like that of freshly ground corn meal ; it belongs to the non-drying group of the vegatable oils, does not easily become rancid, and has no purgative action. With alkalies it forms a white soap; it contains fatty acids (free) 0°88, total fatty acids 96°75 per cent., mucilaginous bodies 1°34. The loss sustained by purification is under 5 per cent. (J. U. Lloyd, Amer. Journ. Pharm., July 1888.) Chemical composition—The average results of the analysis of three varieties of maize in an undried state by Polson, yielded in 100 parts, 54:37 starch, 8:83 nitrogenous substance, 4°50 fat, 2°70 gum and sugar, 15:77 cellulose, 12°16 water, and 1-67 ash. oasis found on an average in 160 parts of the dried grain, 64:5 starch, 6°7 fat, and 9-9 nitrogenous substance. _ Church found it to contain water 12°5, albuminoids 9°5, starch 70-2, oil 3-6, fibre 2-0, ash 1:7. American grain contained a 1 per cent. more fat than Indian. a The following figures, quoted by Konig, represent the mean _ composition of 145 samples examined by various analysts :— Penne cee so vigia aii anlar peat > «Jaa gieell EE ME ep Te re a Ss i eta a = = i ret Sie TB ay Si eee ve a el 7-40 | 22-40} 18:12 554 | 1390] 9-85 a 1-61 8°89 4-62 74°92 | 68°41 Nitrogen-free extractive ...ce:..-| 00°49 Calle... 41-676) 852} 940% 61} 393] 152 Seane Minimum. |Maximum.| Mean. L whet ecw 582 GRAMINE. The stigmata have been examined by C. J. Rademaker and J. L. Fischer (Amer. Journ. Pharm., 1886), with the following results :— Fixed oil (petroleum spirit extract) .......... sc ORS Resin, erystalline principle, and chlorophyll (ether extract) 2°25 Resin, crystalline principle, and chlorophyll (alcoholic extract) 3°25 Sugar, gum, and extractive (water extract) ... 19°50 Albuminoids, phlobaphene, &c. (from alkaline solution) 3°50 Salts and extractive (from acid solution) ...... 5°50 Cellulose 37:00 CS ae 20°00 96°25 LOLIUM TEMULENTUM, Linn. Fig.— Engl. Bot. xvi, t. 1124; Schreb. Gram. ti., t. 36; Bentl. and Trim. 295. Bearded Darnel (Eng.), Ivraie (Fr-)- Hab.—A weed of cultivation. Asia, Europe, North Africa. The seeds. Vernacular.—Miichhni (Hind. ). History, Uses, &c.—A noxious weed growing with wheat called dipa is mentioned by Theophrastus (i., 5), and by Dioscorides (ii., 91) ; the latter writer notices its medicinal use as an external application along with salt and radishes to ulcers, and with sulphur and vinegar to certain skin eruptions, also with pigeon’s dung and linseed. to disperse or mature glandular and gouty swellings. It was also used with bitumen, myrrh, saffron or frankincense as a fumigatory to promote conception. This plant was known to the Romans 45 Lolium, and is mentioned by Virgil (Georg. I) as ‘ infeliv lolium.” Ovid (Fast, i.) speaks of. it as injurious to the : eyesight, “et careant loliis oculos vitiantibus agri.” Pliny — "GRAMINEZ. 583 sila pS ie le mentions it in his chapter upon the diseases of grain (18, 44), and again (22, 58, 77) reproduces the account given by Dios- corides of its medicinal uses. The Arabian lexicographers describe the same plant under the name of Ziwaén or Ziwaén (w!s3) as a noxious weed growing among wheat, which often gives a bad quality to it when accidentally mixed with it, causing giddiness ; they consider it to be the same as the plant called Shailam (#!4%). Abu Hanifeh says, that Shailam is a small, oblong, red, erect grain, resembling in form the (» 5 (or grub) of wheat ; and it does not intoxicate, but renders the wheat very bitter; and in one place he says the plant spreads on the ground, and its leaves are like those of the willow. Ibn Sina describes Ziwdn and Shailam separately, but in his account of their properties there is hardly any difference, it being essentially the same as Dioscorides’ description. of Aira. He states, however, that both are narcotic. Forskal considers Ziwan and Shailam to be different. Of the former he says:—“Zizania Allepensibus notissima: inter - triticum viget: si semina restant farine (sic) mixta, hominem reddunt ex panis esu temulentum: messores plantam non separant ; sed post triturationem vanni aut cribri ope semina Tejiciunt. a of the latter he says: eect etiam agri Mecrme ers a ee ia Rete ES Me ae) oe ae : ini Me te ree awe ; rnptbesi subire debet; Avicenna sic referente.” (£7. Aigypt Arab, p. 199.) Indian Mahometan writers merely copy the Arabians, and we have met with no mention of Darnel by Hindu physicians, In Persia the plant is known as Samuk and Gandum-i-diwaheh “fools? wheat’ In Northern India it is called Michhni “‘bearded”’ : it does not appear to be known in the Peninsula or Bengal. Description. —Annual. Roots a few downy fibres. Stems annual, erect, 8 feet or more in height, stiff, smooth, often branched from the lower nodes. Leaves large, distant ; 18 smooth, striate, ligule short, truncate, blade 5 to 10 584 GRAMINEA, inches long, spreading and drooping, ¢ to 4 inch wide, linear, gradually tapering to the acute apex, dark green. Spikelets large, 4 to 1 inch long, 5 to 11 flowered, sessile, laterally com- - pressed, blunt, arranged singly edgewise alternately on opposite sides of the elongated rachis, forming a narrow distichous spike, 6 to 12 inches long ; rachis somewhat flexuose, hollowed on alternate sides to receive the spikelets, faintly rough ; glumes 2 in the terminal spikelet, nearly equal, only one in the remainder, placed on the outer side of the spikelet, closely appressed, and equalling or exceeding it in length, rather leaf- like, 5-ribbed, convex, smooth, green, subacute, not awned ; pales 2, nearly equal in length, the lower rounded on the back, the edges somewhat involute, 5-ribbed, the two outside ribs very strong, obtuse, and membranous at the apex, a little below which arises usually a straight white awn of variable length, the upper pale flat, appressed to the dorsal one, with its margins folded over on the inside, scarious, with two green veins, faintly ciliate on the edges. Lodicules 2, connected at the base, entire. Stamens 3, ovary rounded. Stigmas 2, as- pergilliform. Fruit enclosed in the pales (the lower one turgid and thickened), oblong-oveid, nearly } inch long, blunt, concave on inner surface, pale brown. Chemical composition.—Filhol and Baillet found the seeds to contain 50 per cent. of starch, albuminoids, and the other constituents found in cereal grains; also a thick, almost con- crete green oil, one portion of which was saponifiable, and the other not. It was insoluble in water, but freely soluble in alcohol and ether. The seeds besides contained an extractive substance soluble in water and alcohol. The non-saponifiable portion of the oil they describe as producing tremulousness when swallowed, but without any narcotism ; and the extractive as narcotic. Both substances proved fatal to animals. Ludwig and Stahl, besides starch, gluten, &c., found two acrid oils soluble in alcohol, but insoluble in water; and an ecrid bitter glucoside, soluble in water ; they attribute the activity of the seeds to the combined influence of these different GRAMINEA. 85 P The still more recent experiments of Wittstein have con- | vinced him ‘that the poisonous characters of the seeds are not due to an acid body, nor to a base, but to an indifferent body which is incapable of forming compounds with lead or zine, and may be completely extracted from the seeds by water or alcohol, and only incompletely by ether.” Dr. P. Antze, who has recently examined the constituents of the plant, both chemically and physiologically, reports (Arch. f. exp. Path. und Pharm., Nov. 1890, p. 126) the isolation of a volatile alkaloid, Joliine,and temulentic acid, which by the action of lime yields a base, ¢emulentine, as a decomposition product. Loliine is said to yield good crystalline salts with sulphuric, hydrochloric, oxalic, and acetic acids, but too small a quantity was obtained for analysis. Injected subcutaneously into rabbits it produced a rise in temperature as well as an increase of the pulse, 0-08 gram being a lethal dose, whilst the narcotic and intoxicating action of the lolium plant seems to be due to temulentic acid and the base obtained from it. The acid, which exists to the extent of about 1 per cent. in the seeds, is | obtained in crystals melting at 934°C. and possessing the approximate composition C*H*NO™, and as well as temulentine Yields good crystalline salts. From experiments upon frogs, Se les ht ee Ed i re ¢. es ak = toxic as loliine and rapidly diminishes the heart’s action, but if the depression, which is accompanied by a marked decrease in temperature, is overcome, the patient assumes a condition of high fever. Dr. Antze recommends, in cases of poisoning with darnel grass, the administration of emetics and purges, followed by stimulants to «raise the depressed action of the heart. (Pharm. Journ., Jan. 31st, 1891.) , Tovicology.—The symptoms which darnel seeds produce on Man are described by Pereira as twofold: ‘those indicating Sastro-intestinal irritation, such as yomiting and colic; and ‘those which arise from disorder of the cerebro-spinal system, _ Such as headache, giddiness, languor, ringing in the ears, _ onfusion of sight, dilated pupil, delirium, heaviness, somno- leney » trembling, convulsions, and paralysis. These seeds, UL. — 74 . “4 rabbits, and the investigator himself, it appears to be twice a8 586 - GRAMINE A. therefore, appear to be acro-narcotic poisons. According to Seeger, one of the most certain signs of poisoning by them is trembling of the whole body.” Death has sometimes resulted from their use, but when suitable remedies have been used, such as evacuants and stimulants, the seeds have not proved fatal to man. Recent experiments made by A. S. Wilson of Aberdeen conclusively proved that healthy darnel seeds have no injurious effects. In selecting healthy seeds, Mr. Wilson observed the grains to be frequently affected by ergot and other fungi, and to be also liable to a disease of a more obscure type. From Dr. P. Antze’s experiments it appears that there are two poisonous principles in the diseased seeds, one an acrid poison giving rise to a febrile condition, and the other a narcotic powerfully depressing the heart’s action, In the Report of the Chemical Examiner, N.-W. Provinces and Oudh, for 1879, the occurrence of darnel-poisoning among the men of the Ghoorkha Regiment at Almora, and also among some of his own servants at Nynee Tal, is recorded, He states that the grass is recognised as injurious by the peasantry in the Moozaffarnagar District, where it is called DMochni. The symptoms observed were vomiting, headache, and great giddiness ; no fatal cases occurred. BAMBUSA ARUNDINACEA, Re:. Fig.— Roxb, Cor, Pi. 4., t. 79- Ltheede, Hort, Mal, i., t. 16. Bamboo (£ng.), Bambou (Ar.). Hab.—Throughout India. The young shoots, seeds, and silicious concretion. Vernacular.—Bains (Hind., Beng.), Vénsa (Guz.), Vansa, Kalaka, Tokara (Mar.), Mangal (Zam.), Bonga, Veduru (TZe/.), Bidungulu (Can.). Bamboo Manna.—Bfns-lochan (Hind.), Béns-képtr (Beng.), V4nsa-lochana (Mar.), Vansa-képira (Guz.), Munga-luppe (Zam.), Veduruppu (Zel.), Bidaruppu (Can.), Moleuppa : GRAMINBA. 587 History, Uses, &c.—The Bamboo, in Sanskrit Vans4 and _ Vénu, is considered by the Hindus to have the hardest of woods, _ The word also signifies ‘spine’ and ‘ lineage,’ thus Vénsa-visuddha means “made of a good bamboo,” ée., of a pure or good family, and Vanga-dhara: “carrying a bamboo,” i.¢., maintaming a family, Vansa-pratishthana-kara “establishing a family on a sure foundation.” The Abbé Dubois, in his Description of India, _ states that the young Indian bride and bridegroom are made 3 to stand in two bamboo baskets placed side by side, and the Kul or Arbor generationis of the caste, at Hindu marriages, is placed in a winnowing fan made of bamboo. The wild tribes _ of the Garrow hills, who have no temples or altars, set up opposite their huts a bamboo post which they deck with flowers 4 and tufts of cotton, and before it they make offerings to their 4 god. Indian anchorites carry a bamboo stick having seven knots. A bamboo flowering is an event of rare occurrence, and which is supposed to bring in its train all sorts of evil, accompanied by dire distress and famine. The seeds of the bamboo, in Sanskrit VanSa-tandula, Vansa-ja, Vénu-yava, Vénu-vija, have often proved of great value in famine seasons, Saving thousands of lives ; this was the case in Orissa in 1812 and in Canara in 1864. The young shoots which appear towards the end of the rainy season are used as a vegetable ; they are minced very finely and soaked in water to remove the Ditter taste, and then cooked with da/, and seasoned according to taste : they are also made into pickle. A decoction of the joints of the bamboo is supposed to have an action on the uterus, and is used by females after delivery to cause a free flow of the lochial discharge. The same part of the plant pounded with water is applied to inflamed joints. The juice of the leaves with aromatics is given in hematemesis. The leaves are very commonly given to horses by syces as a ‘Temedy for coughs and colds. Bamboo manna is the VanSa-lochana of the Indian physi- cians; in the Nirghantés it bears many synonyms, such as anga-rochana, Twvak-kshirdé “ bark-milk,” Vansa-karpura ‘bamboo camphor,” Vanéa-Sarkara “ bamboo sugar,” Vansihva 588 GRAMINE AI. “bamboo sacrifice,” Stbhra, and Sita “white,” &e. It is considered to be strengthening, tonic, cold, and sweet; to alleviate thirst, and to avert phthisis, fever, asthma, cough, biliousness, skin diseases, and Véyu (morbid affections of the windy humor). As an example of the way in which it is prescribed, the following formula for making the Sitopalddi- churna will be found in Sarangadhara:— Bamboo manna 8 parts, long pepper 4, cardamoms 2, cinnamon 1, sugar 16. Powder and mix. Dose about 60 grains, to be given with honey and ghi in phthisis and cachexia. The belief in the strengthening properties of bamboo manna appears to have originated among the aboriginal tribes of India, as on the West Coast it is the first solid food which the Thana Kolis give their children. The same belief seems to have prevailed in Borneo, as Marco Polo relates that pieces of this substance were let in under the skin by the natives to make the body wound-proof. We hold with Salmasins that bamboo manna was the substance known to the Greeks as odxyap vdkxapov, and described. by them as a white, concreted or crystalline substance like common salt, because there was no kind of sugar prepared from the sugar-cane, answering to this description, known in India in the time of Dioscorides. The name Sarkara, which signifies — “grit, pebbles, sand,” was applied by Hindu writers at that time to several substances, viz., Guda or molasses in a dry granular state, the only kind of cane-sugar then in use in India; Yardsa-Sarkara, the concrete manna of Alhagi; and Vansa sarkara, the concretion found in the bamboo, The Sanskrit name Khanda was also applied to Guda, which is the substance known in the vernaculars as Gir or Gil, and is still the kind of sugar most used by the Hindus, Pale crystalline sugar, the Chini of the bazars, does not appear to have been known until some 400 years after the date of Dioscorides. Under the name of Tab4shir, a corruption of the Sanskrit : . _Tvak-kshira, bamboo manna was known to the early Arab _ travellers in the Rast; the port of Thana, on the West Coast of GRAMINE. 589 India, was famous for its TabAshir in the time of Idrisit (1135) and supplied it to all marts. Ibn Sina describes Tabdshir as astringent and stomachic, useful in erysipelas and to allay thirst in bilious dyspepsia, cardiacal, and strengthening. As a local application it is used to relieve the heat and irritation _ caused by aphthous eruptions along with pounded rose leaves. Later Mahomedan writers upon the Materia Medica of the East have added nothing of importance to Ibn Sina’s account of the drug. Fliickiger (Zur Geschichte des Tabaschir, Zeit. des alig. osterr. Apoth. Ver. Nr. 14 u. 15,1887) mentions a list of Indian goods on which transit duty was levied at Aden in 1270; in it Tab4shir is mentioned together with tamarinds and camphor. He also draws attention to a remarkable connection between Tabashir and ivory ashes, generally known by the name of Spodium. Tdrisi, in the middle of the 12th century, points out that the latter was used to adulterate the former, while others of a different opinion assign a greater value to Spodium. Garcia d’Orta( Colloguios51)mentions both Tabéshir and Spodium, which he considers to be Pompholyx or Turtia (white of zine ? ealamine ?), and states that in Persia and Arabia Tabéshir was generally paid for by its weight in silver (‘0 prego ordinario igus Gat es oe = 2 <4 PS Wa. “a 3 burning the bamboo cane. Fliickiger remarks that it is ‘most likely that the name “ Spodium da canna” was given to this _ black Tabdshir or perhaps to the ashes of the cane, and that it might be owing to this circumstance that in later times the _ tame Spodium came to be applied to animal charcoal (bone- black). The idea of black seems not to have been connected _ With the original Greek name o7des (ashes). Flickiger also _ draws attention to the Latin translation of a Persian Karabddin _ or Pharmacopeia by the Carmelite Friar P. Angelus, published in Paris in 1681, in which Tabishir is spoken of as pseudo- spodium, anti-spodium, and spodium-arabicum. Rheede as well Rumphius notice Tabdshir, but it does not appear to have attracted much attention in Europe until Dr. Patrick Russell ‘the attention of the Royal Society to it, and induced. na Persia e Arabia é a peso de prata ”’) ; he also describes black oe : or grey Tabdshir, which was of less value and was obtained by 590 GRAMINEZ:. James Louis Macie to make an analysis, which showed that it consisted principally of silica. Further information on Tabéshir may be obtained from Prof. Fliickiger’ s papers above mentioned, = a paper by Dr. Brandis in the Indian Forester, March, Vol. XIII. Description.—Tabashir consists of irregularly-shaped fragments of an opaque white or bluish opalescent colour, the larger pieces are about an inch in diameter, concavo-convex, and have evidently derived their form from the joint of the bamboo in which the deposit has collected. The raw article is blackened and dirty, having apparently been obtained by burning the bam- - boos, or on account of the presence of insects ; to make it fit for use it is calcined, when it becomes perfectly clean. Chemical composition—Cavendish (Hbenda, 370) determined the specific gravity of Tabashir to be 2-169 at 11:4°C. Humboldt remembered the analysis of Macie when he and Bonpland discovered a similar substance at the voleano of Pichincha, not far from Quito. He wrote from Mexico on the 22nd of April 1803 to Antonio Joseph Cavanilles, Director of the Botanic Garden at Madrid (Annales du Muséum, iv. (An. xil., 1804), 478)—“‘ Vous vous souvenez sans doute de cette substance siliceuse, ressemblante a Popale que M. Macie analysa en Angleterre. Nous l’avons découverte 4 l’ouest du volean Pichincha, dans les bambous ou gros roseaux appelés Guaduas dans le royaume de Santa Fé. J’ai fait des expériences chimiques sur le sue de cette graminée colossale, avant que la substance siliceuse se fit déposée, et jy a remarqué des phénoménes trés-curieux ; il est susceptible d’une putréfaction animale, et parait annoncer une certaine combin- aison d’une terre simple avec l’azote.’? The Guaduas are the representatives of the Indian bamboos in South America and closely related to them. The specimen of American Tabéshir which Humboldt sent to Paris was examined by Foureroy and Vanquelin (dn. du Mus., vi. (1806), 382—385); they found, besides 70 per cent. of silicic acid, 30 per cent. of | abt. Tt would be nteteting to sno if it was prs GRAMINEZ. 591 silicate, which seems possible, as they mention traces of crystallization. The remarkable optical properties of this amorphous silicic acid attracted the attention of Brewster (Trans. Roy. Soc. London (1819), i., 2883—299), who found it to possess very little power of refracting light, and to show when heated in the dark a brilliant phosphorescence. The informa- tion concerning its physical properties given by Brewster was, however, partly contradicted, and, as it seems, with reason, by Guibourt in 1885. Edward Turner (Ebenda, pp. 335—338) found that the substance examined by Brewster could easily be dissolved in a solution of caustic potash, even after having been heated ; the silicic acid separated from the solution, after being heated to redness, weighed nearly as much as the quantity of Tabdshir examined. The transparency which Tabishir acquires when immersed in water was noticed by Brewster and Guibourt; this property is still more striking when it is immersed in a volatile oil or liquid paraffiri, for then with very pure specimens the outlines are scarcely to be distinguished. Guibourt determined its sp. gr. in water to be 27149 at 4°C., and found Indian Tabdshir to be composed of 97°39 per cent. of silicic acid, 2-9 per cent. water, with traces of potash and lime. — In 1859 Fliickiger (Schweizerische Zeitsch. f. Pharm., 1859, 244) examined a very fine specimen of Tabéshir from Java, _ where it is known by the name of Batugining, and found it to be almost pure silicic acid. It would appear, however, to be sometimes mixed or adulterated with the ashes of the cane, as Rost van Tonningen (Jahresb. der Chem., 1860, 531) founda _ Specimen to contain silicic acid 86°38, water 7°63, oxide of iron, potash, and lime 5:99 per cent. The careful examination of Tabdshir made by Poleck (Zeitsch. des osterr, Apoth. Ver., 1887, p. 139) shows beyond doubt that it may be considered to be silicic acid, although the question Temains open, whether it is the normal acid Si(OH*), (Pliickiger, Zur Geschichte des Tabaschir, Zeitsch. des allg. — Osterr, Apoth. Ver, Nr. 14 u. 15, 1887.) As regards the Variations observed in the amount of water contained in this Substance, the reader is referred to our remarks under Commerce. a ce ‘ i 592 GRAMINEA, The ash of bamboo stems has been analysed by Hammer- bacher with the following results: SiO’, 28°264; CaO, 4481; MgO, 6:569 ; KO, 34:217 ; Na?O, 12°765 ; Cl, 2-062 ; S$O0°*, 10°705 ; Ferric phosphate, 0°037=99°100. The fash is rich in silica and alkalis, poor in alkaline earths. The propor- tion of alkalis is about the same asin the ashes of ordinary roots. (Liebig’s Annalen, clxxvi., 87.) Commerce.— Bombay appears to have inherited the ancient trade in Tabdshir which formerly centered in Thana. The raw article is, however, now obtained from Singapore, and is probably the produce of Java and other islands of the Eastern Archipelago. The Indian bamboos being under the protection of the Forest Department prevents their being destroyed to obtain Tabashir, besides they are of much more value for other purposes. The Bombay trade in this article is now the monopoly of a Mahometan, who is the sole importer of the raw material, which he calcines and afterwards sells in bulk at Rs. 2-10 per lb. He also sells a selected quality at Rs. 4 per lb., and an inferior quality at Re. 1-4. The method of calcination is a trade secret. After it has been calcined, Tabashir is placed in water, which it absorbs and increases greatly in weight, becoming cold to the touch; this fact is pointed out to the purchaser as a proof of its cooling qualities. The water is retained by the drug for a long time. SACCHARUM OFFICINARUM, Linn. Fig.— Woodville, t. 266; Tussac, Fl. Antilles, i., tt. 23—20 ; Bentl. and Trim., t. 298. Sugar-cane (E£ng.), Canne 4 sucre (Fr,). Hab.—India. Cultivated in all warm climates. Tho — juice and root. Vernacular.—Ukh, Ganna (Hind.), Ak (Beng.), Us (Mar-.), Shéradi (Guj.), Karumbu (Zam.), Cheruku (Tel.), ac ll : ae ), Khabbu (Care). aa GHRAMINEA. 593 History, Uses, &c.—If the wild form of the sugar-cane is to be anywhere now met with, it is in India, of which country it is undoubtedly a native, and where it has been cultivated from the earliest antiquity. Whether the species grown in China, S. sinense (Roxb. ), is specifically the same is scarcely determined _ with certainty, but itis probably native in that country. (Bendl. _ and Trim.) The Sanskrit name of the plant is Ikshu, and itvtis also called Guda-trina, “the grass from which guda is made,” _ and Guda-diru, &c.; from the juice (Ikshurasa) the ancient Hindus prepared an extract by boiling, which, when soft and sticky, was called Ikshurasa-kvatha, Phanita, and Guda, but varieties of sugar-cane are mentioned by Sanskrit writers, but in this number are probably included other grasses belonging to the genera Saccharum, Sor ghum, &c. The root of the sugar- ane is also used in Hindu medicine, and is considered to have demulcent and diuretic properties. It is an ingredient along with the roots of Saccharum sara, S. spontaneum, Eragrostis Saag ovdes, and Oynodon dactylon in the compounds known as affections of the urinary passages. A kind of rum. was also rom guda and water fermented, which was ceasarins as Sidhu — d Ganda. The unrefined, dark-brown Guda or Phénita of the Hindus known to the ancient Persians as 4#4 (Péniz) and _%* Shakar); from it they manufactured the dry erystalline sugar * they call o3f (Kand) or w ld (Nabat), now piterally ritten oi5 by both Arabs and Persians. We have already Stated (see Article on Bambusa) our reasons for believing that Gdxxapov of Dioscorides was not cane-sugar, viz., that no such article ae sugar in a dry crystalline state was known in India that time, the only kind of sugar used by the Hindus being ark-brown mass known as guda, and which is still the of sugar most popular in India. This substance, as well 3 ~ obtained by the ancient Hindus from the juice of the cane or — ie 594 GRAMINEA. as the guda prepared from the palm (¢oivé), was called by the Greeks wed: (honey), and is mentioned by Herodotus, Theophras- tus, Seneca, Strabo, and other early writers as “‘ Honey of Canes ” and “ Honey made by human hands.” ‘The vernacular names Misri, “Egyptian,” for refined sugar, and Chini, “ Chinese,” for sugar-candy, point to these crystalline forms of sugar as _ comparatively recent introductions into India, and at the present time the sugar-candy of Indian commerce is chiefly imported from China. When we consider that the sugar-cane was known to the ancients from the time of Nearchus, it is hardly reasonable to suppose that Pliny could be so ill-informed as to speak of Saccharum, if by that name he meant cane-sugar, as only employed in medicine. Lucan, writing about the same time, was aware that the Hindus drank the juice of the cane : “Quique bibunt tenera dulces ab arundine succos.” At the present day, the cane-presser, with his primitive press, is a familiar personage at Indian fairs, where he dispenses the luscious juice to his customers at about twopence a pint. Sugar, under the name of Shi-mi “stone honey,” is frequently mentioned in the ancient Chinese annals among the productions of India and Persia; and it is recorded that the Emperor Tai-tsung (A.D. 626—650) sent an envoy to the kingdom of Magadha in India, to learn the method of manu- ‘facturing it. (Bretschneider, Chinese Botanical Works, 1870, 46.) The Chinese acknowledge that the Indians between A.D. 766 pie. 3 GRAMINEM. 595 industry in the shape of millstones, &c., still exist near was. Persian and Arabian physicians of the 10th and 11th centuries, such as Razi, Ali Abbas, and Ibn Sina, introduced sugar (_» Sukkar ) into medicine. The Arabs cultivated the _ ¢ane in many of their Mediterranean settlements, as Cyprus, Sicily, Italy, Northern Africa, and Spain. The Calendar of Cordova shows that as early as A.D. 961 the cultivation was well understood in Spain, which is now the only country in . Europe where sugar-mills still exist. _. The importance of the sugar manufacture in the East was witnessed by Marco Polo, Barbosa, and other European travellers ; and the trading nations of Europe rapidly spread a cultivation of the cane over all the countries of which the te was suitable. The ancient cultivation in Egypt, Bretcbiy never quite extinct, was revised on an extensive scale by the Khedive Ismail Pasha. (Pharmacographia.) ar is of comparatively little value for its independent 3 effects, but few substances are more useful as an associate of _ other medicines, whether to preserve them from oxidation and decomposition, to conceal or improve their taste, or to give them special pharmaceutical forms, In solution sugar is almost exclusively lenitive, but in ‘Powder it is stimulant. It is universally employed to diminish Initigate cough and hoarseness. Sugar dissolved in water issaid © to have a diuretic effect. When injected into the veins of ani- mals it is said to be powerfully diuretic (Richet and M. Martin, Med. Record, xxi., 394). It certainly, when moderately used, promotes diventor and allays nervous excitement. For these purposes sweetened water (eau suerée) is universally employ ed in France and Southern Europe. Formerly a strong ‘Solution of sugar was much used as an antidote to corrosive ‘Poisons. It enters into all the drinks, mucilaginous, farina- eous, and gelatinous, employed in febrile diseases. Finely- wdered sugar will sometimes relieve the hiccough, which, in 596 GRAMINEA, nursing infants, is apt to arise from over-feeding. Loaf-sugar, eaten freely, is said to arrest the development of alcoholic intoxication, perhaps by retarding gastric absorption. A strong solution of sugar injected into the rectum has been used successfully to destroy ascarides of that part. In powder it is very efficient as a remedy for aphthe of the mouth, in repress- ing the exuberant and stimulating the indolent granulations of ulcers, in removing opacities of the cornea, and in curing granular eyelids. Sugar has been claimed by Fischer to be an efficient antiseptic dressing for wounds. He associated it, however, with other antiseptics ; ; but Windelschmidt states that for small wounds sugar is equal to iodoform as a dressing (Med. Neus, xliii., 462). In chronic laryngitis, when inhaled by a sudden aspiration from a tube extending to the root of the tongue, it may be used with advantage alone or mixed with other powders. In the same manner it may be employed as a snuff in chronic ozena. The fumes from burnt sugar destroy offensive effluvia, and are conveniently disengaged by sprinkling sugar upon burning coals or on a hot shovel. (Stillé and Maisch.) We have already referred to the use of sweetmeats by opium-eaters to counteract the effects of the drag (p. 96, Vol. I.). Oultivation.—The sugar-cane season comprises nearly a twelvemonth. The land chosen is usually a good loam or _ light clay manured. The leafy ends of the preceding season’s canes are cut off, or the whole cane is chopped into pieces so a8 in any case to include two nodes or joints, and these, to the number of about 20,000 per acre, are planted in furrows in January and February. The land is irrigated occasionally from this time to the commencement of the rains. The harvest begins in the beginning of December, and the cutting and crushing of the canes and boiling of the juice is carried on till January and February. Excepting the few mills under European management, the crushing and boiling is performed by primitive, and, therefore, rude processes. The average _ _outturn per cent. of cane in the North-West Provinces is st a #, Mees. Duthie and Fuller to be as follows: a aE S GRAMINEA. 597 _ of juice=18 of guda (unrefined sugar) or 17°5 of shakar * (dry, unrefined sugar), or 19°5 of rdb (syrupy sugar). The natives generally manufacture the juice into the two kinds of guda, called in the vernaculars géra or gula. Description.—The transverse section of a sugar-cane exhibits numerous fibro-vascular bundles, scattered through the tissue, as in other monocotyledonous stems ; these bundles are most abundant towards the exterior, where they form a dense ring covered with a thin epidermis, which is very hard from the quantity of silica deposited in it. In the centre of the stem the vascular bundles are few in number, and traverse an abundant parenchyma which contains in its thin-walled _ ¢ells an almost clear solution of sugar, with a few small starch _ granules and a little soluble albuminous matter. The latter is found in larger quantity in the cambial portion of the vascular ; 3 bundles. The walls of the medullary cells contain pectic _ matter, but not in sufficient quantity to cause them to swell — much in water. (Wiesner.) The unrefined sugar of India 3 (géra or gula), often incorrectly termed molasses, occurs in two 4 forms in the bazars—one is a blackish sticky mass without 3 evident crystalline structure, the other is a SS party _ ¢rystalline mass which crumbles on pressure, erally _ Spoken of by the dealers as floury gér or oli ae ‘first _ contains the whole of the unerystallizable portion of the syrup, e in the other most of this has been drained off. Indi _ Molasses or treacle is of a very dark colour, of a peculiar sharp flavour, and has a bitterish after-taste caused by the presence in it of caramel or burnt sugar, produced during the careless evaporation of the cane juice. It is hardly suited for pharmaceutical purposes, an and as sold in the bazars is generally freely watered and ina state of fermentation. The refined ‘Sugars of Indian commerce are manufactured on the European System, chiefly i in Bengal, or are imported from Mauritius, and, et leg gh a lege . (6. er ~—* Called by Europeans Jaggery, a corruption of the Sanskrit Sarkara, in Ceylon is the vernacular name for unrefined sugar in the ¢ hakkare. 598 GRAMINE ZL. in the case of loaf-sugar, from France. They differ in no respect from the sugars of European commerce. Chemical composition.—The sugar-cane is, when mature, composed of cellulose 8 to 12 per cent.; sugar 18 to 21; water, including albuminous matter and salts, 67 to 73. Of the entire quantity of juice in the cane, from 70 to 84 per cent. can be extracted by crushing and pressing, and yields in a crystalline state about three-fifths of the sugar which the cane originally contained. The juice has on an average the following composition :— Albuminous matters 0-03 Granular matter (starch ?) ..........s0ccesc0e 0°10 Mucilage containing nitrogen ............0+- 0°22 Salts, mostly of organic acids ............-.. 0-29 Sugar ‘ 18-36 Water .. 81:00 100-00 There is also present in the juice a very small amount of @ slightly aromatic substance (essential oil?) to which the crude cane-sugar owes a peculiar odour which is not observed in sugar from other sources. (Pharmacographia.) Sugar, CHO", may be obtained in large transparent rhombic prisms, known as swgar-candy, which does not differ from lump-sugar, except that the latter is in crystalline masses from disturbed crystallization. Sugar has the specific gravity 1-58 (Kopp), is permanent in the air, neutral, without odour, has * very sweet taste, and dissolves at ordinary temperatures 1? one-half its weight of water, yielding a dense, sweet, = colourless liquid known as syrup; saturated at 15° C. such & solution contains 66 per cent. of sugar, and this has ses density 1°345082 (Michel and Kraft). At the boiling- pa _ Sugar dissolves in water almost in all proportions. It requires GRAMINEM. 599 for solution about 80 parts of boiling absolute alcohol, 28 parts of boiling officinal alcohol, and about 4 parts of boiling alcohol, spec. grav. *830, these solutions depositing most of the sugar on cooling. The solubility is greater in weak alcohol, both cold and hot. At 15°C. 1 part of sugar dissolves in 2 parts of 60 per cent. alcohol, in 7-7 parts of 75 per cent. alcohol, in 14°7 parts of 80 per cent. alcohol, in 31:6 parts of 85 per cent. _ alcohol, in 175 parts of 92 per cent. alcohol, and in 228 parts of _ metbylic alcohol of the same strength (Casamajor). Sugar dissolves also in glycerin, the solubility being increased on _ dilution with water, but it is insoluble in ether, chloroform, _ earbon disulphide, and in hydrocarbons. It combines with chloride of sodium, yielding deliquescent crystals which contain _ 149 per cent. of that salt. Definite compounds have likewise been obtained with several other salts and with alkalies and _ alkalineearths, When trituratedin the dark it becomes luminous. _ Its solution deviates polarized light to the right—a behaviour _ which is of great practical importance for the estimation of _ Sugar in aqueous liquids and for distinguishing different kinds’ 4q of sugar which have a different rotary power. When sugar is heated to 160° C. it melts without losing in _ Weight, and congeals on cooling to a transparent amorphous _ Yellowish mass known as barley-sugar, saccharum hordeatum, _ Which becomes gradually opaque on the surface from the _ formation of minute crystals. If sugar is kept in the melted State between 160° and 170° C. for a short time, it is converted Into a deliquescent mixture of glucose and levulosan ; 0’*H**O™ _ Yields C*H'?0°+C*°H"°0°; the latter is not fermentable until _ after it has been ‘boiled with water or dilute acids. When heated to between 180° and 200° C. sugar turns brown, evolves @ peculiar odour, and is converted into caramel, C*H™O®, Parting at the same time with 2H’0; the pure product of this Composition, caramelan, was obtained colourless by Gélis (1862), Caramel may be prepared in the same manner from inferior qualities of sugar, from molasses, and from glucose, and the Conversion is hastened in the presence of small quantities of ‘ ies; the addition of a little carbonate of ammonium, which s 600 GRAMINEA. is again volatilized by the heat, is of service, for the reason stated. Subjected to dry distillation, sugar yields aldehyd, acetone, acetic acid, tarry products, and carbonic acid, carbonic oxide, and marsh gas, According to Lassaigne, iodine heated with solution of sugar is converted into hydriodic acid. Under the influence of ferments, as well as of dilute acids, cane-sugar is converted into invert-sugar, which is a mixture of dextrose or ape-sugar and Jevulose or fruit-sugar, and is directly fermentable. This inversion of sugar takes place slowly on boiling with water, but cold aqueous solutions keep unaltered for a long time, provided the access of ferments suspended in the air be prevented. Under the same condition, according to the investigations of Kreusler, Lemoine, and others, light does not exert the inverting effect reported by Raoul (1871). Nitrie acid inverts cane-sugar, readily, and when heated with it produces saccharic, racemic, tartaric, and oxalic acids, Tests.—The purity of cane-sugar is ascertained by the physical properties described above and by its complete solubility in water and alcohol. The absence of glucose or of a similar sugar is ascertained by some of the reactions given below. “‘ Aqueous and alcoholic solutions of sugar should have no effect on litmus-paper. The solution in 20 parts of distilled water should be scarcely rendered turbid by silver nitrate or barium nitrate (chloride and sulphate).” Neither an aqueous nor an alcoholic solution of sugar kept in large, well-closed, and completely-filled bottles should deposit 4 sediment on prolonged standing (absence of insoluble salts, foreign matters, ultramarine, Prussian blue, &e. }i of a portion | of about 1 Gm. of sugar be dissolved in 10 em. of boiling water, then mixed with 4 or 5 drops of test solution of nitrate of silver and about 2 cm. of water of ammonia, and quickly heated until the liquid begins to boil, not more than a slight coloration, but no black precipitate should appear in the Ligeai after standing at rest for 5 minutes (absence of grape-Ssuga? and of more than a cl amount of inverted ee (sui and —— po GRAMINER, 601 Commerce.—The following statistics of the trade in Sugar are taken from the Reports on the inland trade of the different provinces and on the trade by sea: Value in lakhs ae of Rupees Quantity in thousands of cwts. ARTICLES, % % 5 8 B 6 os g = ao|{m|o |]. oO nt Ce) 19 ve S\2/2/8 8 |e (ee 2 ugar, refined.. 10 41 4) 3] .144) 38) 33) 25) ewts. mDo. unrefined . 45) 42) 46) 50} 869) 1,009) 953)1,143 Total ...| 55) 46) 50) 53) 1,013, 1,047] 986]1,168) ewts. r, refined...| ...| 18} 20} 21] ... 150| 158) 163) ewts, ORYZA SATIVA, Linn. ig.—Benti. and Trim., t. 291; Rheede, Hort. Mal. v., 201. Rice (Eng.), Riz (Fr.). Hab. —Throughout India, wild and cultivated. The » Spirit, and vinegar. oe ernacular.—Dhéin (Hind., Beng.), Bhat (Mar.), Chokha ae -), Arishi (Zam.), Biyyam (Tel.), Akki (Can.). dusked Rice.--Chival (Hind., Beng.), Téndula (Mar.). istory, Uses, &c.—Wild rice was probably used by boriginal tribes of India in prehistoric times ; it is still fully collected by the peasantry, who consider it to have al virtues, and call it “ god’s rice,” “ hermit’s rice,” &e. (aif vrihe ) is not mentioned in the Rig-Veda, but in the pa- Veda it is noticed along with barley, masha (Phaseolus rghit), and sesamum. Rice cultivation in India appears “ been subsequent to that of China and Burma. Girard tualle, in his Mythologie comparée, states that the Karens of believe that every plant has its Ja or kelah (spirit), as its spirit, and when the crop is bad, they pray to it 602 GRAMINEZE. in the following terms: ‘‘ Come, O spirit of the rice, come back ! come to the rice-field, come to the rice! come from the East, come from the West, come from the beak of the bird, from the mouth of the monkey, from the throat of the elephant, come from the grain stores! O kelah of the rice, return to the rice!” In Siam they offer rice and cakes to trees before cutting them down. In Bengal sacrifices of rice are made to the Bael tree, probably a survival of an ancient fetish worship which the Brahmins have sanctioned by deifying the tree. Rice plays an important part in the marriage ceremonies of the Hindus. According to the Grihya-sutra of Asvalayana, the bride must walk three times round the altar, and at the completion of each turn make an offering of rice. This ceremony resembles an ancient form of marrying among the Romans, in which an offering of a cake made of fér (spelt)* was made in the presence of the Pontifex Maximus or Flamen Dialis and ten witnesses. _ Parched rice, Ldjd, also called Syélé (Sya “a winnowing fan,” and /é for Jéjd), is scattered by the bride’s brother at marriages. Rice is poured over the head of the bride and bridegroom as an emblem of life, regeneration and plenty. On the fourth day of the marriage ceremonies the young couple eat rice together for the first and only time in their lives, and on the last day they both celebrate together the Soma ‘sacrifice, when they throw Idjé into the fire. At the birth of a child the father places the red ,Akshata rice on its forehead to avert evil, and when the child is named it is placed ona cloth covered with rice. Rice is also used in some parts of India to detect witches: a small bag of rice, bearing the name of each of the suspected parties, is placed in a white-ants’ nest, and the one they first eat is considered to belong to the guilty party. When several persons are suspected of a crime, rice is sometimes used to detect the guilty one— _ For this purpose the persons are required to chew rice, the = criminal being discovered by his inability to properly masticate - tbe * Triticum Speita, Linn., or German wheat. a a GRAMINBA. 603 it, owing probably to fear checking the free flow of saliva. Vincenzo Maria da Santa Caterina mentions in his travels that rice and turmeric are offered in India to the gods to obtain children and the cure of female diseases, and that young © girls make a vow to offer rice, should they obtain a good husband. In the consecration of the Brahmachari, the father of the youth carries in his hands a ecupful of rice, and the assistants after the bath cover the candidate with rice. Asvalayana says that the disciple asks alms to learn the Ved4s; he obtains the rice as alms and must cook it before sunset. His commentator, Narayana, adds that when the rice has been cooked, the disciple should say to his raster, “the food of the pot is ready.” In sacrifices to Rudra, according to Asvalayana, the husk of rice was thrown into the _ fire along with the smallest grains, and the tail, skin, head, and feet of the animal, and that the latter before being killed was sprinkled with rice and barley-water. In times of fasting and penitence, grains of rice and barley are watered and blessed and offered to the gods. In funeral 4 ceremonies rice and other food is offered to crows. According to Manu, the twice-born are directed to offer five great sacrifices, aie _ with herbs, roots, and fruits. oan ih ae The practice of worshipping the new rice at the time of the harvest is common throughout India. In Bengal, on a Thursday, inthe month of Pansha (December-January), after the crop has been reaped, a rattan-made grain measure called reh, filled With the grain upon which are placed gold, silver and copper coins and some cowrie shells, is worshipped as the representative (ofthe goddess of fortune. This worship is repeated in the months of Chaitra, Sravana, and Kartika. In Western India ‘le new rice is worshipped at the Dasara and Devali festivals, and in Madras the same event is celebrated by the Pongo/ ceremony, when the new rice is boiled for the first time and eaten with ‘Steat rejoicings. Among the Native Catholics the same cere- ny is perpetuated in the “blessing of the new rice,” which done by the priest in the field before the crop is cut. vis., with wild rice (Nivéra), with various pure substances, Or = 604 GRAMINEA. That the cultivation of rice had widely spread in the time of Alexander (400 B.C.) we learn from Strabo, who says, ice ing to Aristobulus, rice grows in Bactriana, Babylonia, Susida, " and he adds, ‘we may also say in Lower Syria.” F urther on he notes that the Indians use it for food, and extract a spirit from it. The Greek names for rice are derived from the Sans- krit Vrihi ; the earliest form occurs in a fragment of Sophocles, where rice-bread is called épivdns dpros ; in later writers we meet with the form épvg{a, The Arabic names have the same deri- vation, the oldest form being Runz, occurring in the local dialect of the Abd-el-Kais, near Bahrain, and the more modern — forms Aruzz and Ruzz. In Persian the form of Birinj is eur- rent, as well as the Sanskrit name Shali, for unhusked _ Dioscorides briefly mentions rice as being of little nutriti ve value and apt to cause costiveness. Celsus ., 20) classes it along with wheat and spelt as “‘ res boni succi.’”’ According to Sanskrit writers, the best class of grains includes wheat, rice, and barley only, other kinds being relegated to the class Kshdidre dhénya or inferior grains. The preparationsof rice used in the diet of sick people, and described in Sanskrit medical works, are :— 7aq (yavagu) or powdered rice boiled with water. It is made of three strengths, namely, with nine, eleven, and nineteen parts of water, called, respectively, Vilepi, Peyd, and Manda. Instead of water, a light decoction of some aromatic and carminative drug, such as ginger or pepper, may be used in preparing abdys. erm (14j4) or unhusked rice parched in hot sand. It is used as light and digestible diet for the sick. wes (brishta tandula) or husked rice parched in hot sand. It is used for the same purposes as /a7d. qyat (prithuké) or unhusked rice moistened, parched, and afterwards flattened and the husk removed. It is soaked in water or boiled and given with curdled mide: as an war a y diet i in diarrhoea or dysentery. GRAMINEA. 605 qq (paiyasa) or rice-milk. A well-known preparation. qgarq (tandulambu) or water in which unboiled rice has been steeped. This is often used as a vehicle for powders, &e., and as a diet drink. Rice is the staple-food of the inhabitants in Bengal, many parts of Madras, Burma, and the Western Coast of India, but not of the central and northern parts of the country, where wheat and millet are the staples and rice only a luxury. We secre ie Se os ae Ie, ee ee ON ee on Fens me ; Fermented and distilled rice liquors are largely used in many parts of India. For an account of the economic uses of the grain, its cultivation, and the numerous varieties of the plant met with in different parts of the country, we must refer the reader to a diffuse but interesting article by Dr. G. Watt in the Dictionary of the Econ. Prod. of India. =e _ Chemical composition.—Rice has been examined by Letheby, Payen, and others. Payen gives the percentage composition of dried rice, as, nitrogenous matter 7°55, carbohydrates 90°75, closely resembles the potato; one hundred parts of dried potato, according to Letheby’s analysis, contain, nitrogenous Matter 8-4, carbohydrates 88, fat 0°8, and saline matters 2°8 parts per cent. bee Church (Food Grains of India) gives the following percentage composition of cleaned rice :—Water 12°8, albuminoids 7:3, _ Temarks, 100 parts of rice contain no more than ‘065 of potash and -284 of phosphoric acid. Kénig quotes 20 analyses of Tice by various chemists, the mean percentage composition being, Water 13-11, albuminoids 7°85, fat °88, nitrogen-free extract and Starch 76-52, cellulose *63, ash 1°01. Where rice constitutes almost the entire food of the population, the throwing away the water in which it has been boiled involves the loss of some of the ‘Mineral matter, and is to be deprecated ; no more water should be used in cooking this grain than can be absorbed by it. ‘Two nds of cleaned rice weigh 5 pounds after boiling. 606 GRAMINEZ. Commerce.—The following table shows the exports of Rice (husked) from India during the last ten years in thousands of ewts :-— Value in Year, Burma. | Bengal. | Madras. stent Sind. | Total, | lakhs of y- Rup 1880-81....../16,730| 6,717| 2,363 927] 32 |26,769| 89,717 1881-82...... 16,690) 7,617/| 1,549 614} 49 | 28,519) 82,496 1882-83......| 21,249] 7,838] 1,319 552] 71 |31,029| 84,401 1883-84...... 16,994) 7,394| 1,843 521] 80 | 26,882) 83,289 1884-85...... 13,507) 6,035) 1,403) 677} 80 | 21,702) 71,228 1885-86......| 19,084) 6,879| 1,181| 521] 149 | 27,814) 91,672 1886-87...... 18,216) 5,902} 1,564| 639] 139 | 26,460) 87,648 1887-88..,... 17,879| 7,996| 1,488) 764) 72 | 28,149) 92,251 1888-89...... 14,205) 6,417| 1,538) 589] 19 | 22,768) 78,453 1889-990...... 18,259) 5,992| 1,654| 799) 70 | 26,774; 100,473 Average for| 10 years...| 17,491] 6,878| 1,585| 660| 76 |26,681| 86,162 _ The estimated total production of given as :— Bengal ...... Madras N.-W. Provinces and O Punjab rice in 1888-89 has been . 14,269,223 tons. 2,693,916 Central Provinces Burma ...... Assam udh, 399,757 » 2,420,768 271,293 1,622,385 3,039,397 608,846 25,325,585 tons. ————— In the same year India imported from beyond its frontier 1,151,450 ewts., the greater portion coming from Nepaul. Of the exports, about 50 per cent, goes to Europe, 30 per cent, to — Eastern ports, and the remainder for the use of the emigrants im Mauritius, Réunion, the West Indies, South America, and GRAMINEZ. 607 Australia. The fine rice of the West Indies is considered. insipid by the Indian labourers, 7 TRITICUM SATIVUM, Lam. Fig.— Bentl. and Trim., t. 294. Wheat (Eng.), Blé (Fr.). : Hab.—The Euphrates region. Cultivated in N.-W. India, __ the Central Provinces, and Bombay. _- Vernacular. —Géhun (Hind.), Gahun (Mar.), Godumai (Tam.), — Godumulu (Te/.), Kotanpam (Mal.), Godhi (Can.), Gam (Beng.), Ghavum (Guz.). : _ History, Uses, &c.— Wheat, as the most important of _ the cereals, has given rise to numerous myths, for an account _ of which we cannot do better than refer the reader to the late a Dr. W. Mannhardt’s learned monograph Die Komendimonen _ (Berlin, 1868). In the myth of Persephone-kora, daughter of - us, the god of the heavens, which by their warmth and rain produce fertility, and of Dimeter or Ceres, the maternal goddess of the fertile earth, we perceive that she was conceived a8 a divine personification of this grain, in summer appearing beside her mother in the light of the upper world, but in the autumn disappearing, and in winter passing her time, like the _ seed under the earth, with the god of the lower world. Asa pendant to the Greek myth, we have the Indian myth of Sita or “ the Furrow,”’ husbandry personified, and apparently once. Worshipped as a kind of goddess. In the Rig-Veda Sita is invoked as a deity presiding over Agriculture, and appears to be associated with Indra. In the Vdjasaneya, Sita “ the urow” is personified and addressed, four furrows being Tequired to be drawn at the ceremony when certain stanzas are ited. Sita is so named because she was fabled to have Sprung from a furrow made by her father Janaka while hing the ground to prepare it for a sacrifice instituted by 4m to obtain progeny, whence her epithet Ayonija “ not $mb-born.”* Wheat was used in sacrifice by the Greeks and ees ee Course, these myths are more Or less applicable to all food-grains. 608 GRAMINEAS. Romans, and by the Hindus in Vedic times, as an emblem of fertility ; it was poured upon the bride at the marriage ceremony, and in Northern India, wheat, millet and rice are still used on such occasions. Wheat, as the most important food-grain, is frequently mentioned by Hippocrates, who calls it tvpés, and mentions three kinds; Pliny also describes several kinds of Triticum, Sanskrit medical writers also mention three kinds of wheat, namely, Mah4godhuma or large-grained, Madhuli or small-grained, and Nihsuki or beardless ; they consider it to be the most nutritive of the food-grains, but not so easily digested as rice. Many varieties of wheat are cultivated in India, and through careless cultivation there is much mixture in the samples brought to market. A number of samples purchased by one of us in the Bombay market and sent to Australia for trial, were, on careful cultivation, found to be all mixed, some of them producing five or six distinct varieties. Indian wheats may be divided roughly into two classes, soft and hard, the former being mostly used for bread-making, and the latter for making a kind of vermicelli and certain other preparations used by the natives. Amongst the Hindus, owing to caste distinctions, the whole process of grinding the corn, separating the flour and making it into cakes, is usually performed by the women of the house, consequently the demand for ready-made flour is limited to the supply of the non-Hindu population, and some of the less particular Hindu castes. In the Indian process of making flour, the wheat, after cleaning, is placed upon a table and thoroughly wetted and the water allowed to drain from it during the night. The next morning, the still moist grain is ground in handmills by women. It is then sifted, and as much fine flour and ravwa or swji (the heart of the grain) as can be obtained are laid aside. The remainder termed “naka” is again ground in a more powerful mill and an inferior kind of rawa obtained from it. The residue after a third grinding yields a coarse flour and bran. The bazar-made bread is of : two kinds, that used by the Mahometans and known as Wén, ich is in thin cakes, and loaf-bread introduced by the GRAMINEZ, ae Portuguese. The former is similar to the bread used in all Mahometan countries, the latter is made with 60 parts fine rawa, 20 second sort or naka raiwa, and 20 of first sort flour. A second or inferior kind of bread is also sold. The barm or yeast in use is, where obtainable, the fermenting juice of the palm, elsewhere an artificial barm is prepared. In some of the large towns a loaf-bread ismow made by _ Brahmins for the use of the Hindu population, but its useis very limited. In Calcutta, Madras, and Bombay, flour andbread _ made as in Europe is obtainable, and is gradually taking the place of the Portuguese article. Fine flour is also imported from Europe and America, as the excessive proportion of gluten in Indian flour renders it unsuitable for use in making pastry. - Wheaten flour is often used as a dusting-powder to allay the heat and pain of local inflammations, such as burns, scalds, but itis inferior for such purposes to powdered starch. America an uncooked paste made of the flour has been used h butcess in diarrhea. In India flour is much used by the tives for making poultices. er than longitudinally. In the vicinity of the furrow alone tissue of the albumen is narrower. Its predominating ge cells show a polygonal or oval outline, whilst the outer layer is built up of two, three or four rows of thick-walled, ) erent, nearly cubic gluten-cells. This layer, about 70 mkm. thick, is coated with an extremely thin brown tegument, to Ww: hich succeeds a layer about 30 mkm. thick, of densely packed, | tabular, greyish or yellowish cells of very small size; this proper of the fruit in the furrow is.of rather spongy appearance. » gluten-cells, varying considerably in the different cereal afford characters enough to distinguish them with ity, In wheat, for instance, the gluten-cells are In a —7 610 QRAMINEZE. single row, in rice they forma double or single row, but its cells are transversely lengthened. The layer alluded to as being composed of gluten-cells is loaded with extremely small granules of albuminous matters (gluten), which on addition of iodine are coloured intensely yellow. These granules, which, considering barley as an article of food, are of prominent value, are not confined to the gluten- cells, but the neighbouring starch-cells also contain a small amount of them: and in the narrow zone of denser tissue projecting from the furrow into the albumen, protein principles are equally deposited, as shown by the yellow coloration which iodine produces. The gluten-cells, the membrane embroynnaire of Mége-Mouriés, contain also, according to the researches on bread made by this chemist (1856), Cerealin, an albuminous principle soluble in water, which causes the transformation of starch into dextrin, sugar, and lactic acid. In the husks (épiderme, épicarpe, and endocarpe) of wheat, Mége-Mouriés found some volatile oil and a yellow extractive matter, to which, together with the cerealin, is due the acidity of bread made with the flour containing the bran. Chemical composition.—Kénig quotes 200 analyses of wheat from different sources and by various chemists, and the following figures represent the minimum, maximum, and mean composition :— Water. Albuminoids. Fat. Nitrogen-free Cellulose. Ash. Minimum..5:33 7-61 «1-00 59-90 1:24 52 Maximum.1910 21.37 3-57. 73-77. @ 34.268 Mean ......1365 1235 1-75 6791 953 181 According to Church (Food Grains of India), average Indian wheat has the following percentage composition :— Water 12°5, albuminoids 13-5, starch 68:4, oil 1-2, fibre 277; ash 17. The albuminoids in some samples examined were as high as 167. In English and American wheat they _ Tange from 8 to 9 per cent, only. The amount of j - ——— between 60 and 70 per cent., and the weight tie . ~ QRAMINES. 611 nitrogen between 1-6 and 2-7 per cent. A small quantity of saccharine matter is also present, and the ash contains nearly 50 per cent. of phosphoric acid. The inorganic constituents are mostly found in the bran, to the extent of over 7 per cent., while the nitrogenated principles enter chiefly the flour. If the latter be kneaded with cold water as long as the liquid becomes milky, a yellowish gray elastic and glutinous mass remains, which is the gie‘en of Beccaria, retains about 70 per cent. of water, and consists, according to Von Bibra, in the dry state, of about 70 per cent. vegetable fibrin, 38 to 9-3 vegetable casein, 7:5 to 19°5 glutin, and 4°6 to 8°2 per cent. of fat. When fresh it dissolves in dilute phosphoric acid and in solution of potassa. On drying it assumes a hornlike appearance and partly loses its solubility. According to Boussingault, it contains 14 per cent. of nitrogen. To purify it, Ritthausen (1862-67) dissolves it in cold very dilute potassa solution (1 to 1,000 parts of water), decants from _ the undissolved starch, and precipitates with acetic acid. The __, Precipitate is repeatedly treated with fresh portions of alcohol, _ €ommencing with spec. gr. ‘914, and increasing the strength finally to absolute aleohol. After another washing with ether, the insoluble portion constitutes gluten-casem, which is slightly ae soluble in acetic acid, freely soluble in potassa, and becomes’ insoluble by heat. On evaporating the united alcoholic liquids to one-half and cooling, gluten-fibrin is separated, which 1s freed from adhering casein by dissolving it repeatedly in 60 and 70 per cent. alcohol. It is freely soluble in dilute acetic acid, and when boiled with water, in which it is insoluble, it is Converted into a jelly. After the separation of gluten-fibrin, evaporated; the pre- with a little alcohol, and precipitated by absolute alcohol. The precipitate is _ mitcedin; the solution contains glutin or gliadin. The former a Yields with cold or boiling water a milk-like liquid; the latter 48 soluble in water, alcohol, acetic acid, potassa, &e., the ueous solution being precipitated by the salts of the heavier 612 GRAMINE ZZ. metals; glutin contains sulphur and 18 per cent. of nitrogen. - These principles are the most important ones of the veg getable protein compounds. (Stillé and Maisch.) Starch forms a white, inodorous, and tasteless powder, with a peculiar slippery feel between the fingers. Exposed to the atmosphere, it contains from 10 to 13 per cent. of moisture, which is giyen off at 100° C. (212° F.), and is reabsorbed on exposure. The spec. gray. of starch is about 1:5, but after complete drying is increased to 1°56, It is insoluble in ether, alcohol, and cold water; the last-mentioned liquid, however, when triturated with starch, so that some of the granules are ruptured, evidently dissolves a little, since it acquires, after - filtration, a blue color on the addition of iodine. Soluble starch is obtained, according to ae by the prolonged heating of starch to 100° C. (212° F.). When heated to between 160° and 200° C. (820° and 392° F.), it is gradually converted into dextrin (see below). Starch becomes soluble in cold water in — the presence of the chlorides of zine and of caleium and of - other deliquescent or freely soluble salts. Its solution in hot water gelatinizes on cooling, the jelly of wheat starch being milk-white—that of potato starch, particularly when made with much water, being more translucent. On heating starch with glycerin a solution is obtained, which, according to Zulkowski (1875, 1880), contains soluble starch, obtainable by diluting with water and precipitating the clear filtrate with alcohol. Potatostarch is easily converted into the soluble form, but wheat starch requires a prolonged heating, and rice starch is thus changed with still greater difhculty. Preparation.—Wheat or other grain is soaked in warm water, to which sometimes an alkali is added, until the outer coating has become soft ; ; itis then ground under water, and washed upon suitable sieves with pure water, with which the starch passes through and is collected by subsidence in suitable tanks, the alkaline water retaining the gluten ; or the latter is removed by allowing it to undergo decomposition, when acetios 3 utyric, or lactic other acids are produced, The gluten — not be destrc 0} ny bt maybe obsined ay a hyped | GRAMINEAE. 615 for this purpose wheat flour is made with water into a stiff dough ; this is set aside for 2 hours, and then placed upon a fine wire sieve, where it is kneaded under a thin stream of water until the latter no longer becomes milky ; nearly the whole of the gluten will remain upon the sieve. After sufficient washing with pure water, the starch is drained in boxes, cut into cubical blocks, and dried in properly-constructed drying chambers. Mucilage of starch, when heated to about 160° C. (320° F.), or when boiled with very dilute sulphuric acid, or when digested with diastase at about 70° CG. (158° F.), is converted, according to Musculus (1860), first into maltose, OVO, which is probably a compound of dextrin, CHO", and dextrose, C°H"0°, the former passing finally likewise into glucose. Todine imparts to starch in the presence of water, and to starch- mucilage, a blue color which disappears on the application of heat, but reappears on cooling. Bromine colors the starch brown-yellow. Fuming nitric acid transforms starch into tyloidin, C°H% NO?)O°, which is a white, tasteless powder, insoluble in alcohol, but softening in boiling water. A filtered solution of starch in water yields with tannin a flocculent precipitate which is soluble in boiling water. When incinerated, — starch should leave not over 1 per cent. of ash. i eae The exports of Wheat from India to Europe last year exceedet 1,397,000 tons, an, increase on the shipments f the previous — twelve months of 725,000 tons, or 110 per eent., and they were Jarger than the previous largest shipments in any year, that of 1886, by 265,000 tons, or 23°4 per cent. In the past seven talendar years the exports from the three great shipping ports have been as under :— oo ; Fro Total — at | oes ccmeliee Calcutta. | _ Tons. _ | 665,543] 512,632| 219,221 | 1,397,466 ... | 272,644 | 334,042 65,439 | 672,126 “| 305/044) 341,187| 77,637 | 723,818 : ws | 483,035 149,277 | 148,776 781,088 ...| 462,428] 32,977 99,012 | 724,417 1 | 6777834] 186,352+ 328,558 | 1,182,744 .a. | 542,562) 807,844 412,277 | 1,062,683 614 GRAMINUA. The shipments from Bombay show an increase on the preced: ing year of 144°5 per cent., those from Kurrachee of 53:6, and from Calcutta of 236-9 per cent. ‘The share of these three ports in the trade in the past two years and in 1886 has been as under :— 1891 1890 1886 Per cent Per cent Per cent Bombay ... er 47°6 40°6 54:5 Kurrachee oa 36°7 49°7 157 Calcutta. 15-7 9-7 29:8 Three years ago Kurrachee took the lead, and in the follow- ing year she increased it, thanks to the large crops in the Punjab, from whence she draws the bulk of her supplies. Last year the crop in the Punjab, the largest wheat-producing pro- vince in India, was a bumper one, and as the demand from Hurope was more than usual, the exports from the chief port of Sind were far in excess of any previous year, and exceeded half a million tons. But she was, nevertheless, unable to main- tain her supremacy. With full crops in the Central Provinces and in the North-West Provinces and Oudh, but under the average in this Presidency, Bombay once again took the lead with ‘a total of close on 666,000 tons, or about 30 per cent. more than from Kurrachee and a 11 per cent. larger share in the total exports from the country. To the larger crop in the .-W. Provinces and QOudh the increased shipments from Calcutta are due, for in Bengal the crop was slightly under the mean; but her future position, as an exporter of Wheat, is bound to weaken, rather than improve, on that held by the ports on the Western side. In the past seven years on an average 51 per cent. of the shipments have been despatched to Great Britain and 49 to the Continent, but last year only 41 per cent. went to U. K. Ports and 59 to the rest of Europe- Of the shipments from Bombay in 1891, the Continent received 63 per cent. from Kurrachee nearly as much—viz., 61 per : cent.,— but from Calcutta only 41 per cent. went. The crop _ how growing promises well in the Punjab and North-West _ Provinces, in both of which the area was recently estimated GRAMINEA. 615 as larger than last year: in the former at about one, and in the latter at four per cent. more, or about 10? and 11 per cent., respectively, in excess of the normal area. In the Central Provinces and in this Presidency, the estimates, when completed, are expected to fall short of both last year and the average, owing to the season being unfavourable for the later sowings, but in Berar the area is returned at over two per cent, more than last year’s. More rain is wanted, especially in the Central Provinces, Berar, and in parts of our own Presi- dency, and unless it soon falls the outturn will be still further reduced. A large business in Punjab Wheat was done a few months ago for April-May delivery in Bombay, but owing to the dealers in the Central Provinces holding out for new terms of sale in the local market, very little of the grain of those pro- vinces has so far been contracted for. ‘I‘hey have only recently given way, and agreed to sell on the old terms, too late, however, for the market has slipped back and prices have dropped con- siderably from their former high level. HORDEUM HEXASTICHUM, Lin. Fig.— Duthie, Fodder Grasses of N. India, Pi. F, I 32. Barley (Zng.), Orge (F.). Hab.— Western temperate Asia. Cultivated in the N -W. Provinces of India. Vernacular.—Jay (Hind.), Jab (Beng.), Java (Mar. Tel.). History Uses, &c.—Indra in the Rig- Veda is called durah yavasya, “the giver of the barley.” At many Hindu Ceremonies, such as the birth of a child, marriages, funerals, and in various sacrifices, barley is used. In the Atharva-Veda the rice and barley offered to the dead are prayed to to be Propitious to them, and in the same Veda rice and barley are Mvoked for the cure of disease and deliverance from other evils: Bray yakshmain vi bédhete; etau mun’ch’ato anhasas.” Barley is symbolic of wealth and plenty; it is also a phallic emblem ; Asvalayana, in the first book of the Grihyasutra, says 616 GRAMINEZ:. that in Vedic times, the wife when three months gone with child fasted; after her fast, her husband came to her with a pot of sour milk into which he threw two beans and a grain of barley, and whilst she was drinking it, he asked, “ What drinkest thou?” She, having drunk three times, replied, 7 drink to the birth of a son.” Ndrdyana, in his Commentary on Asyalfyana, states that the two beans and the grain of barley represent the organs of generation. (De Gubernatis.) At the Yava-chaturthi, on the fourth day of the light half of the month Vaisiékh, a sort of game is played in which people throw barley-meal over each other. Yava-sura, al intoxicating drink, is made from barley in Northern India. According to Bretschneider, barley is included among the five cereals, which, it is related in Chinese history, were sowed by the Emperor Sheh-nung, who reigned about 2700 B.C. ; but it is not one of the five sorts of grain which are used at the ceremony of ploughing and sowing as now annually performed by the _ emperors of China. Theophrastus was acquainted with several sorts of barley (Kp:@n), and, among them, with the six-rowed kind or hexasti- chon, which is the species that is represented on the coins struck at Metapontum in Lucania between the 6th and 2nd centuries B.C. Barley is mentioned in the Bible as a plant of cultivation in Egypt and Syria, and must have been, among the ancient Hebrews, an important article of food, judging from the quantity allowed by Solomon to the servant of Hiram, king of Tyre (B.C. 1015). The tribute of barley paid to King Jotham by the Ammonites (B.C. 741) is also exactly recorded. The ancients were frequently in the practice of removing the hard integuments of barley by roasting it, and using the torrified grain as food. (Pharmacographia.) The Hindus employ barley in the dietary of the sick. It is : Gruel prepared from saktu is said to be easily diges _ chiefly used in the form of saktu or powder of the parched 4 to be useful in painful dyspepsia. In Europe, for use i SE oe a ee RE fey en ae ae eee ee np Eee ee gener a 8 ars cE Se eo ae ee i ae eee et aera GRAMINE A. 617 medicine and as food for the sick, pearl-barley is always employed; this is the grain deprived of its husk by passing it between horizontal mill-stones, placed so far apart as to rub off the integuments without crushing it. Pearl-barley imported from Europe is obtainable in most Indian bazars. For an account of the economic uses of barley, we would refer the _ reader to an article by Dr. J. Murray in the Diet. Econ. Prod. of India (iv., p. 273). Description.—The structure of the barley-grain after the palew have been removed is similar to that of wheat (see Triticum), The palee consist chiefly of long fibrous, thick- walled cells, two or four rows deep, constituting a very hard _ layer. On transverse section, this layer forms a coherent enyelope, about 35 mkm. thick; its cells, when examined in longitudinal section, show but a small lumen of peculiar - undulated outline from secondary deposits. (Pharmacographia.) — Chemical composition.—The following figures representing the average minimum, maximum, and mean composition of a samples of barley from different sources are quoted by Water. Albuminoids. Fat. 60 extract. Cellulose. 3 ie jn Vee 6°20 1:08 49°14 1-96. Maximum...20°88 17:46 487 7220 1416 002 ao?!” 4iae 2:16 64:93 Or “S00 © © According to Church, the average percentage composition ot 7 usked Indian barley is, water 12°5, albuminoids 11°5, starch 70-0, oil 1-3, fibre 2:6, ash 2°1. ~ Lermer (Vierteljahresschr. fur prakt. Pharm, XIT. (1863), 4-23) found European barley to have the following percentage composition :—Water 13 to 15, oil 3-0, starch 63-0, cellulose 7-0, dextrin 6°6, nitrogen 2°5, ash 2°4, lactic acid a trace. The protein or albuminous matter consists of different principles, shiefly insoluble in cold water. The soluble portion is partly lated on boiling, partly retained in solution. 2°5 percent. Togen, as above, would answer to about 16 per cent of 78 Lit 7 Ash. 5 618 GRAMINEZ. _ albuminous matters. Their soluble part seems to be deposited in the starch-cells, next to the gluten cells, which latter contain the insoluble portion. The ash, according to Lermer, contains 29 per cent. of silicic acid, 32°6 of phosphoric acid, 22°7 of potash, and only 3°7 of lime, In the opinion of Salm-Horstmar, fluorine and lithia are indispensable constituents of barley. The fixed oil of barley, as proved in 1863 by Hanamann, is -acompound of glycerine, with either a mixture of palmitic and lauric acids, or less probably with a peculiar fatty acid. Beck- mann’s Hordeinie Acid obtained in 1855 by distilling barley with sulphuric acid is probably lauric acid, Lintner (1868) has shown barley to contain also a little Cholesterin. Lastly, Kithnemann (1875) extracted from barley a crystal- lized dextrogyrate sugar, and (1876) an amorphous levogyrate mucilaginous substance, Sinistrin ; according to that chemist, dextrin is altogether wanting in barley. : Barley when malted loses 7 per cent. ; it then contains 10 to 12 per cent. of sugar, produced at the expense of the starch; before malting no sugar is to be found. (Pharmacographia.) ~ Commerce.—The total yield of barley in British India does not exceed 50,000,000 ewts. In 1887-88 the total exports were 29,575 ewts., valued at Rs. 89,776, of which Bombay shipped 18,688 cwts., Bengal 6,873 cwts., and Sind 4,014 ewts., valued at Rs, 58,682, Rs. 20,556, and Rs. 10,588, respectively. The country which imported most largely was Persia, with 10,358 ewts. ; following on which were, Arabia with 7,675 ewts., Ceylon with 7,539 ewts., and Aden, the United Kingdom, Zanzibar, and “other countries” with insignificant quantities. (Dict. Econ. Prod. India, iv., p- 281.) +8 minor food grains (Kudhénya or Kehudar dhanya) | mentioned by Sanskrit medical writers are :— Sorghum vulgare, Pors.—YaAvanéla (Sanskrit), Joér (Hind. Beng.), Tavéri (Guz.), Jondhalé (Mar.), Cholum (Tam.)> aes ‘ i ey a patie! ae GRAMINE. 619 This is one of the most important food-crops of India; from __ it are made bread, porridge, and other food preparations. © Church’s analysis shows it to have the following percentage composition :— Water 12-5, albuminoids 9-3, starch 72°3, oil 2°0, fibre 2:2, ash 1-7, phosphoric acid 0°85, potash 0-21. Setaria italica, Beawy.—Kangu (Sanskrit), Kora (Hind.), Kéngni (Beng.), Kéli-kéngani (Mar.), Bajri (G@us.), Tennai (Lam.), Koréld (Tel.). The grain is much esteemed as an article of human food -™ some parts of India. It is eaten in the form of cakes and - Porridge in the North-West Provinces and Bombay ; in Madras _ itis valued as a material for making pastry, in the Punjab the leaves are used as a pot-herb. Boiled with milk it forms a _ light and pleasant meal for invalids. Church’s analysis shows _ it to have the following percentage composition:— Water 10°2, albuminoids 10:8, shale 73°4, oil 2°9, fibre 1°5, ash 1°2 (husked), Panicum miliaceum, Zinn.—China (Sanskrit), China : ind.), China-ghés (Beng.), Varagu (Zam.), Vorglo (Tel), Varivava (Mar.). sop This grain is usually made use of in the form of porridge i hurch’s analysis shows it to have the following pe entage Composition:—Water 12-0, albuminoids 12-6, — 3°6, fibre 1-0, ash 1:4 (husked). die gage e Panicum frumentaceum, forb.—Syémika (Sanskrit), 4 Sawan (Hind. ), Shyémédhén (Beng.), Shamélu (Zel.), Kathli, | Shamila (Mar.), Savan, Sama (@uz.). _ This grain is wholesome and nourshing, and is much used for home consumption amongst the poorer classes. Church’s “analysis shows it to have the following percentage €omposition :—Water 12:0, albuminoids 8°4, starch 72-5, oil 3°0, fibre 2:2, ash 12:9 (unhusked). Paspalum scrobicuiutum, Linn.—Kodrava (Senshi, Oda (Hind.), Kodoédh4n (Beng.), Arugu (Tei.), Gora-harik, kodru (Mar., Guz.). 620 GRAMIN EA. Cases of poisoning are occasionally met with in India, arising from the consumption of this grain as an article of food. The symptoms are similar to those seen in poisoning by darnel (see Lolium temulentum). Kodru-poisoning occasionally ends fatally : thus, in a case reported to the Bombay Chemical Analyser, from Godhra, in 1879-80, four persons, viz, a man and three children, were poisoned by eating bread made from the flour, and one of the children died. This grain appears to be only occasionally poisonous; according to popular belief, _ there are two varieties of the grain, Gora or “ sweet,” and Majara or “ poisonous,” Church’s analysis shows the following percentage composition of the husked grain:—Water 11:7, albuminoids & 0, starch 77:2, oil 2°1, fibre 0°7, ash 1°3. _Hygrorhiza aristata, Nees.—Nivéra (Sanskrit), Uridhin (Hind., Beng.), Deobhat (Mar.). See article on Rice. Church’s analysis shows that wild rice, after it has been husked, has the following percentage composition :— Water 12-8, albuminoids 7:3, starch 78°3, oil 0°6, fibre 0-4, ash 0°6. Eleusine corocana, Gértn. —Rigi (Sanskrit), Mandua, Mandal (Hind.), Marua (Beng.), Kayur (Zam.), Ponassa (Te/.), Ragi (Can.), Nachni, Négli (Mar.). This grain is much used by the poorer classes in Western India, usually in the form of porridge. It is considered to be particularly wholesome and digestible, and a thin gruel made from it is much used mixed with cow’s milk for weaning children and as a diet for invalids. In Goa thin biscuits are prepared with the flour, from which a gruel can at once be made. Church’s analysis shows the grain to lacie the following percentage composition :—Water 13° 2, albuminoids. 73, starch 73:2, oil 15, fibre 2:5, ash 2°3, phosphoric acid 0-4, | FILICES. 621 (Sanskrit.), Deodhén (Hind., Beng.), Shalu (MMar.), Iniphi (Guz). A food grain of much value. Church’s analysis shows it to have the following percentage composition:—Water 12°8, albuminoids 11°8, starch 68:3, oil 3°0, fibre 3:0, ash 1°], sugar 6 to 18. ; : Sorghumsac charatum, Mench. —Devadhinya Saccharum sara, Roxb.—Charuka (Sanskrit), Sarpa, Sara (Hind), Sarabij (Beng.), Gundra, Sura (Zam., Tel.), Sara (Dar.). . The seed of this grass appears to be only used in famine times, or by some of the wild tribes who use the stem for making arrows. The seeds of Coix and Bambusa, which are also classed amongst the Kshudra-dhdnya, have been already noticed. : Festuca indica (Rheede, xii., 45) is used to resolve phlegmons. FILICES. POLYPODIUM VULGARE, Linn, : baer © . Fig.—Eng. Bot., 1149; Woodv. Suppl. t. 271, Common Polypody (Eng.), Polypode de chéne (/%-). Hab.—Persia, Europe. The rhizomes. Vernacular.—Basfaij (Ind. Bazars). History, Uses, &c.—This fern is the modrurdbior of Theo- phrastus and Dioscorides, both of whom mention its purgative properties. Dioscorides states that it is used to expel bile and phlegm. Pliny (26, 37) says:—“ The root of polypadion, known to usas filicula, is used medicinally, being fibrous and of a grass- green colour within, about the thickness of the little finger, and Covered with cavernous suckers like those on the arms of the polypus. It is of a sweetish taste, and is found growing among 622 FILICES. rocks and under trees. ‘The root is steeped in water, and the juice extracted ; sometimes, too, it is cut in small pieces and sprinkled upon cabbage, beet, mallows, or salt meat ; or else it is boiled in pap asa gentle aperient for the bowels. It carries off bile and the pituitous humors, but acts injuriously upon the stomach. Dried and powdered and applied to the nostrils, it cauterizes polypus of the nose. It has neither seed nor flower. In Germany there was a myth in ancient times that the plant sprang from the milk of the goddess Freya, and in more recent times the Virgin Mary was credited with its origin. Owing to the sweetness of the rhizome, it is, in some parts of France, called “reglisse”’ or “liquorice.” The Persians call the plant Tashtiwin and Baspdfk; the latter name in the Arabic form of. Basfaij is now current throughout the East as the name of the drug, and is used by Ibn Sina and the Arabian physicians. The Arabian names for the plant are, Azras-el-kalb ‘dog's tooth,” in allusion to the _ toothed appearance of the leaves, ee een! ‘“‘many-footed,”’ and Thékib- -el-hajar ‘‘ penetrating stones.” The Mahometan physicians use it as an aperient, deobstruent, and alterative combined with myrobalans and fumitory ; they consider that it acts as an expeller of all kinds of peccant humors; for instance, we have seen it prescribed in cataract and amaurosis by Indian hakims. It is not an article of the Hindu Materia Medica, Description.—The dried rhizome occurs in pieces of various lengths, and of the thickness of a quill. It is flattened, of a yellowish-brown colour externally, green internally, but when old yellowish ; the upper surface is studded with tubercles, tosome of which a portion of the base of the frond still adheres. The under surface is more or less spinous from the remains of < broken radicles. The taste is sweetish, astringent, nauseous, and somewhat aerid ; odour ferny. Under the microscope, the thizome is seen to consist of a delicate cellular structure containing much starch and green granular matter; it is Se = large bundles of sealariform vessels. _ eS FILICRS. 623 POLYPODIUM QUERCIFOLIUM, Spr. Fig.— Rheede, Hort. Mal. zii., t, 11. Oak-leayed Polypody (Eng.). ; _ Hab.—India. Widely distributed throughout the East. _ The rhizome. Vernacular.—Béasing, Vandar-basing, Ashva-katri (Mar.). History, Uses, &c,— Basing (arfar1), the Marathi name of this remarkable fern, signifies the crown-like frontlet which the Marathi people tie upon the forehead of the bride and bridegroom at the marriage ceremony. There can be little doubt that the form of the ornament was suggested by . the appearance of the plant ; its use is of very ancient date, and : 4 probably derived from the aboriginal inhabitants of the hilly =" districts of Western India, where P. quercifolium is very _ abundant. The thick silky rhizome of this fern is found _ Closely adhering to the dead branches of trees, which it - envelopes with its large oak-like leaves. Rheede says that the _ plant is supposed by the natives of Malabar to partake of the properties of whatever tree it grows upon. This notion — Prevails all over India with regard to this and other parasites — (see Loranthacee), and, as has already been shown, is quit erroneous, eee ae. For medicinal purposes those plants which grow upon the = =— _ Strychnos Nuzx-vomica are preferred. The author of the — | _ Wanaushadi Prakésha gives the following prescription contain- ing Bésing as the best cure for phthisis :—Take 2 tolds of K4jrabising, 1 tola Ooksi flowers (Calycopteris floribunda), 2 tolas Chiretta, 2 tolais Ghas-pitpapra ( Rostellularia procumbens), 2 tolés Ringan-mil (root of Solanum indicum), 2 tolés Bal-bel- Phal (small immature fruit of gle Marmelos), 2 tolds Padminimal (root of Nelumbium speciosum), 4 tol4s Sonar-wel- mtil (root of Vicoa indica), two tolés Gokhru-mil (root of Tribulus terrestris). These nine drugs are to be powdered and divided into seven parts. For administration each part is to be boiled in ‘40 tolaés of water, sweetened with 2 toldés of ’ 624 | FILICHS sugar-candy, and the decoction (kara) boiled down to one- eighth ; this is to be taken in the morning, and the marc is to be again treated in the same manner to furnish the nikéra (aecond decoction) or evening dose. The same prescription is recom- mended in hectic fever from whatever cause, and in dyspepsia and cough ; during its use potatoes and indigestible vegetables are to be avoided. Rheede (xii., 12, 13) has the following remarks upon the medicinal use of Prigvodiate taccifolium in Malabar :—‘“‘Succus radicis vermes enecat, bilem sistit et temperat. Folia in pulverem redacta cum melle assumpta secundinas, menses, imo fotum ipsum fortiter ejiciunt ; mulieres ergo cavete vobis.”’ ADIANTUM VENUSTUM, Don. Fig.— Hook. Sp. Fil. ii., 40; Bedd. Ferns. Brit. Ind. xx. Hab.—Himalaya, Afghanistan, Persia. The plant. Vernacular.—Hansréj, Mobarkha (Ind. Bazars). History, Uses, &c.—Under the name of @diartoy a fern is described by Dioscorides as having leaves serrated at the top like coriander ( PvAAdpia 2yer kopidyBpo Spora ere xtopeva eT dxopov ), This plant was doubtless Adiantum Capiilus Veneris, twin, the same description would apply equally well to A, venus- but which has been adopted by the Mahometan physicians of the Hast as representing the @.avrov of the Greeks. The Western Arabs, however, appear to use A, Oapillus Veneris, as they call the plant Kuzburat-el-bir or “ coriander of the well,” indicating a habitat where 4. venustum is not found, Other Arabic names for the genus Adiantum are oe inn “ fairies’ hair,” Shaar-el-jibal “hair of, the mountains,’ Shaar-el-fual ‘“ hair of omens,” Sék-el-aswad “ black stem,” Nasif-el-aswad “ black veil,” &¢.° Ibn Sina and other medical writes describe the drug under the name of Barsiawashén, which is the Arabian _ form of the Persian name Parsiawashén. It is considered to = be deobstruent and resolvent, useful for clearing the prime i. of bile, adust bile, and phlegmatic humors ; also pectoral, FILICES. 625 expectorant, diuretic, emmenagogue, and alexipharmic. Used asa plaster it is considered to be discutient, and is applied to chronic tumours of various kinds. The author of the Burhdn states that the ashes of the plant mixed with olive oil and vinegar are used to make the hair grow upon the bald patches produced by ringworm of the scalp. Theophrastus (H. P., vii., 13) mentions two kinds of Adiantum, “white” and “black,” used in making hair oil. Greck synonyms for the plant were politrichon, calitrichon, trichomanes, and ebinotrichon. In France a syrup of Maiden-hair is much used as a pectoral ; the officinal plant is 4. pedatum, Linn., or Capillaire du Canada, but 4. trapeziforme, Linn., Capillaire du Mexique, is allowed as a substitute. Description.—Fronds 3 to 4 times pinnate. Rachis slender, polished, naked ; segments rigid, prominently veined and toothed, upper edge rounded, lower cuneate into the petiole ; sori one to three, large, roundish, placed in a distinct _ hollow on the upper edge. Commerce.—The Maiden-hair of commerce consists solely of A. venuslum, imported from Persia in large bales which contain 4number of small bundles, five or six of which weigh one — Pound. Value, 3 annas per Ib. Other species of Adiantum — are used locally to a small extent. ASPLENIUM PARASITICUM, Wild. Pig. —Rhecde, Hort. Mal. ii., t. 17. Vernacular.—K iri-béli-p4nna-maravara (Mai.), War.), Kali-pindan (Goa). Maha-pana ASPLENIUM FALCATUM, Wild. Fig.— Rhcede, Hort. Mal. zii.; t. 18+ Hab.—India. The rhizomes. _ Pernacular.—Nela-pinna-maravara (Ma/.), Pana (Mar.), 626 FILICES. History, Uses, &c.—The medicinal use of these ferns is due’ to the Portuguese, who, on their settling in India, adopted them as substitutes for Asplenium of Europe. A fern called demdnvov or domdnvos réa was supposed by the ancients to have the property of reducing the size of the spleen 5 it was also known as ckodoréviniov “ centipede plant,” from a fancied resemblance of its fronds to that reptile, and jpévor “mule plant,” because mules were reputed to be fond of feed- ing upon it. Dioscorides mentions the use of a decoction of the plant in vinegar for enlargement of the spleen, and also the local application of a plaster made of the leaves steeped in wine. It was also considered to be of use in incontinence of urine, cal- culus, and jaundice. Women were not allowed to use it, as it was supposed to cause sterility. This plant is generally iden- tified with the Asplenium Ceterach of Linneus, «Spleen-wort ” or “Milt waste ”’; others have supposed it to be A. hemionitis, Linn., “ Mules’ fern,’ or A. Scolopendrium, Linn., “ Hart’s tongue.” ees Mahometan physicians, under the name of Iskélikandriin, give a translation of what Dioscorides says concerning this drug, with a few unimportant additions ; practically they appear to know nothing about it, and we have never known any drug to be offered under this name in the bazars. Haji Zein states that it is called Hashishat-el-tihé] « Spleen-wort’’ in Arabic, and in Egypt Kaf-el-nasar “ Eagle’s clan.” The Indian substitute is used in Goa as an alterative in cases of prolonged malarial fever, usually in combination with Olden- landia or Andrographis, and the use of the drug has spread to Malabar through the Goan Brahmins who have settled there. Description.—The part used medicinally is the rhizome, to which are attached the bases of the fronds and numerous radicles, all of a black colour. The rhizome is about as thick as the finger; when broken across it is seen to consist of a parenchyma in which are several bundles of vessels of a lighter colour. These can be separated from the canals in which they ; situated without much trouble when the rhizome is fresh. a LICHENES. : 627 Under the microscope, the cell-walls of the parenchyma appear of a dark-brown colour, and the vascular bundles are seen to consist of large scalariform vessels. It has an astringent and slightly bitter taste. Actinopteris dichotoma, Bedd. Vern.—Mor-pankhi, Mayuraka. A fern which grows in the Nilgiri and Himalaya Mountains, and upon rocks and old walls in the Deccan, but is rare in the plains of India; it is used asa styptic. “ Actinopteris is a genus of polypodiaceous fern of the section Aspleniew, and consists of curious little plants like miniature fan palms. The technical peculiarities of the genus among the Aspleniez consist in the simple distinct indusia, free veins, and linear-elongate sori, which are marginal on the contracted rachiform segments of the small flabelliform fronds.” (Z. Moore in “ Treasury of Botany.) Atkinson states that this fern is used as an anthelmintic. LICHEN ES. PARMELIA KAMTSCHADALIS, Eesch. Hab. ; Himalaya, Persia. PARMELIA PERLATA, sch. - Fig—Eng. Bot., 341. Hab.—lIndia, Europe, Africa. The plant. Vernacular.—Charéla, Charcharéla, Pathar-ke-phal, Silé-bék 4 (Hind), Motha-dagada-phil, Barik-dagada-phiil (Mar.), Ghabilo, Chadila (@uz.), Kalpasi, Kalapu (Zam.), Ratipanché (7/.). | History, Uses, &c.—Two lichens are found in all Indian bazars, which are known as the greater and lesser “ stone-flowers” in the vernaculars, and in Sanskrit as Sil4-valka or “rock-bark.” Similar plants were known to the Greeks as 8ptov and ogdyves, and to the Romans as Muscus. Dioscorides “(i., 22) notices their medicinal properties, also Pliny (xi., 61), The Arabs call. them Ushnah, a name derived from the 628 FUNGI, Persian, and Hazaz-el-sakhar ‘‘ rock-scab.” Leith says:—“ It is a thing that spreads itself upon the trees called Bait and Sanibar (oak and pine) as though it were pared off from a root (Gr5 w? 9880 +I); and it is sweet in odour, and white.” (Kamis.) In Persia these lichens are known as Ushnah and Dowdlah. The author of the Makhzan-el-Adwiya states that Ushnah grows upon the oak, cypress, and other trees; that which is whitest should be preferred; it should have an agree- able odour. He describes it as astringent, resolvent, and aperient, and says that the decoction is used as a tonic and alterative; when burnt, the smoke relieves headache, the powder is a good cephalic snuff. Externally the drug has emollient and astringent properties, and may be used in a bath or asa poultice, &e. The dry powder is applied to wounds and sores to promote granulation. Honigberger mentions the use of the drug at Lahore in disorders of the stomach, dyspepsia, vomiting, pain in the liver or womb, induration of the uterus, amenorrhea, calculi, and nocturnal spermatic discharges. ? Ainslie (ii., 170) says : “ Kull-pashie is the Tamool name given to a dried pale-coloured rock moss, which the Vytians suppose to possess a peculiar cooling quality, and prepare with it a liniment for the head.” The use of these lichens in the form of a poultice, placed over the renal and lumbar regions to produce diuresis, is noticed in the Pharmacopeia of India, FUNGI. MYLITTA LAPIDESCENS, Zoran. Pig.— Trans. Linn. Soc., vol, wxiti,, t. 9; p. 97. Hab.—India and China. Vernacular.—Carom-pallagum (Tam.), Lay-wan (China). a a History, Uses, &c.—This curious underground fungus — _ 1s supposed to be allied to the truffles, and is used in Southera — ig i # a Cee eee ae i Mie oe a Ss a i inte ria a be 2 PO IE Ree ar yee FUNGI. 629 Indiaas medicine and food. In 1860 Dr. E. J. Waring forwarded to Mr. Hanbury some specimens of these tuberiform productions, and they were examined by Mr, M. J. Berkeley and Mr. Currey. These specimens had been dug out from the chalk-beds in the mountains between Travancore and Tinnevelly, and the hill- people were in the habit of bringing them into Trevandrum for sale. They are much esteemed by native doctors for various complaints, and they are regarded as diuretic, The Tamil name signifies Black Pallagum, Pallagum meaning a medicinal substance. The fungus frequently appears on the Nilgiris, and the Badagas, Karumbars, and other hill-tribes call it “God’s bread ”’ or ‘ Little man’s bread,” and use it for food. In 1889 the Peziza was very plentiful in the Government Cinchona Plantations at Naduvatam, and the specimens were found over a wide area about one foot beneath the surface of the ground. Planters on other parts of the hills have noticed their periodical occurrence in their estates, and the coolies always collect and cook them for their meals. Description.—These fungoid bodies are like small tubers having a black, finely-wrinkled surface, and the inside is white and marked with veins, and a microscopic section shows the division of the tissue into areole similar to that exhibited by hypogzeous fungi. In a fresh state they have a waxy consistence, but when dry they are hard and horny. Some fresh slices immersed in glycerine for several weeks showed no crystalline or crystalloid formations, and starch was entirely absent, Chemical composition.—The dried Peziza yielded 1 per cent. of carbonated ash. Boiled with dilute hydrochloric acid a solution was formed, reducing Fehling’s test and inactive towards polarised light. Boiled with soda alarge quantity of pectinous matter was dissolved. BOLETUS CROCATUS, Batsch. oi Hab.-—-India, on the Jack-tree (Artocarpus integrifolia, | Vernacular.—Phansimba (Bazars), Phanas-alombé (Jar). 630 FUNGI, History, Uses, &c.—The only notice of this fungus, which we have met with, occurs in Rumphius (Hort. Amb., ir, 25), where he says:—‘“In Malabara ac Zeylana ex eodem quoque succo circa radices colligitur et concrescit in terra massa, seu tuber Portugallis Jsca de Jaca (tinder of the Jack-tree) dictum, quod molle est et intus flavescit, quod natio ista pro experto habet medicamento contra diarrhceam, ad paucas vero tantum colligitur arbores, atque inde venale in alias quoque transfertur regiones.’’ It appears to be probable that the medicinal use of this fungus was introduced into the East by the Portuguese, who adopted it as a substitute for the Boletus fomentarius of Linneus, the Agaricus Chirurgorum or “surgeon’s agaric” of the old European Pharmacopeias, which the Portuguese call Isca de ferir “wound tinder,” and the French Agaric de chéne or Polypore ongulé. It is the Spunk or Touchwood of the English. In Western India the fungus is ground to a paste with water and applied to the gums in cases of excessive salivation. It is also applied to the mouths of children suffering from _ aphthe, and is given internally in diarrhoea and dysentery. Description.—In form this fungus closely resembles the European Boletus above referred to, and resembles the hoof of a horse. Internally it is of a rich orange-brown colour when fresh, and has a sweetish, styptic taste, but when long kept it turns to a dull brown colour. The fungus consists of a number of lamine upon the under surface of which the hymenium is situated, Chemical composition.—A proximate ae yielded :— Ether extract : i 78 Alcoholic extract .., : reo Aqueous extract ié ‘asl 470 kaline extract .. i 34 Crude fibre... “i a 53°98 sh fae wan eee 285 es 4: 3U Moisture os Ne se LO U8 a 100-00 pe yh ia 2 p> PE CS ee EET TE NS Re Ce Mee i eee FUNGI. 631 The ether and alcoholic extracts consisted of red-coloured resins, but no fatty matter. The aqueous extract contained 2°42 per cent. of an organic acid not related to tannin in its reaction with ferric chloride and gelatine. Solution of soda removed an acid resin having some of the properties of polyporic acid. ’ POLYPORUS OFFICINALIS, Fries. Fig.—Guibourt, Hist. Nat. ii., 45; Pereira, Mat. Med. ii., Pt. 1, p. 54. Larch Agaric (Hng.), Polypore du Méléze, Agaric blanc (F*.). Hab.—Southern Europe, Asia Minor. On the Larch. The fungus. Vernacular.—Ghérikén (Indian Bazars). History, Uses, &c.—The use of this fungus in medicine is of very ancient date. Dioscorides (iii., 1) describes dyapixsv _. as male and female, the female being the best and having internally a comb-like structure, whilst the male is convolute, round and compact (cwves); both have the same taste, at first sweet, afterwards bitter. He states that it grows in Sarmatia, Galatia in Asia, and Cilicia, and that some suppose it to be a root and others a fungus. It is astringent, hot, and Z purgative, and is also given in fever, jaundice, nephritis, uterine obstructions, phthisis, dyspepsia, hemorrhage, and pains in the joints; it is alexipharmic. Pliny (25, 57) says : “ Agaric is found growing in the form of a fungus of a white colour, upon the trees in the vicinity of the Bosporus. It is administered in doses of four oboli, beaten up in two cyathi of oxymel. The kind that grows in Galatia is generally looked upon as not so efficacious. The male* agaric is firmer than _* This distinction into male and female is no longer recognized, though ) _ it continued to be so till within the last century. ( Bostock.) 632 FUNGI. Pereira states that the drug appears in the modern Greek Pharmacopewia under the name of dyapixdy 76 Aevxov with the Turkish synonym of ‘atpay partape, Ibn Sina insists upon the great efficacy of agaric (ws )') as an alexipharmic. He and other Mahometan physicians closely follow the Greeks in their description of its medicinal properties; they consider that it removes all kinds of visceral obstructions and expels diseased humors; the female kind should be used after it has been rubbed through a hair-sieve and all black particles removed. The use of agaric in phthisis is of ancient date; it was revived by De Haen, Barbut, and others in the present century, and subsequently decried by Andral (Phil. Trans., Vols. 48 and 49). The active principle, agaricin, has recently been recommended in doses of ;’g to & of a grain as an astringent to check night-sweating and diarrhea, to.diminish bronchial secretion, and to dry up the milk after weaning. _. Description.—Pileus corky-fleshy, ungulate, zoned, _ smooth, Pores yellowish. Berkeley describes the hymenium as concrete with the substance of the pileus, consisting of sub- rotund spores with their simple dissepiments. The drug is decorticated, dried, and bleached, and oceurs in white, friable - pieces, from the size of the fist to that of a child’s head, which are more or less ungulate or of the shape of half a cone, with a feeble fungous odour and bitter acrid taste. The fungus, when met with in its natural state, has an external yellowish or reddish-grey coat, Chemical composition— White Agaric has been analysed by Bouillon-La-Grange, by Bucholz, by Braconnot, and by Bley- The constituents, according to Bley, are: resin, 33°1; extrac- tive, 2; gum and bitter extractive, 8-3; vegetable albumen, O75 wax, 0°2; fungic acids, 0-13; boletic acid, 0-06; tartaric and phosphoric acids, 1°354; potash, 0:329; lime, 0°16; ammonia and sulphur, traces. _ = aaa 3 _ The active principle of Agaric has usually been said to reside — | in the resin, but a white amorphous bitter powder (lariein) has 2 FUNGI. 638 been separated from it, the formula of which, according to Will, is C*'H’*O*. Martius considers this to be the active prin- ciple. Fleury (J. Pharm. Ohim, (4) XXI., 279 to 284) gives the following result of an examination of the drug:—Five hundred and eighty grams of the powdered fungus, not previously dried, were exhausted successively with ether, alcohol, cold water, boiling water, water acidulated with hydrochloric acid, and water rendered alkaline with potash, and the resulting solutions were examine 1. The ether extracts a resin, and a body to which the name of Agaric acid is given. The examination of several salts of ) this acid yielded results so discordant that no definite formula could be obtained, but the nearest approaches to accuracy lead to the supposition that its formula may be C**H**O’. Efforts made to determine the basicity of the acid were unsuccessful. It is shown that the addition of the elements of water to the resin represents the composition of the agaric acid. After heat- ing with very dilute sulphuric acid, a substance is yielded which reduces the cupro-potassic liquor, The agaric acid amounts to about one-fifth of the weight of the fungus. 2. The alcoholic solution has a very red colour, due appa- body soluble in alkaline liquids; its reaction is acid, it is not co erystallizable, and it contains 1°5 per cent. of nitrogen. It combines with metallic oxides. ‘The remainder behaves like a Tesin; it is reddish, nitrogenized, fusible below 100°, forms Viscous solutions with alkalies, and gelatinous precipitates with other bases. 3. Cold water yields a red solution, which on concentration deposits calcic and possibly also magnesic¢ oxalate in microscopic crystals, while the solution contains a brown resinous nitro- genous body, considered to be identical with Boudier’s viscosin. ~ 4. Boiling water extracts a sinall quantity of a nitrogenous Substance, ilI.—so rently to the air, and on evaporation yields a residue of the — eae consistence of hard wax, from which ether dissolves a resinous eee 634 ; «FUNG - 8. Water acidulated with hydrochloric acid (2 per cent.) yields a yellowish solution containing lime, iron, magnesia, and oxalic, phosphoric and malic acids. 6. Water contaiing 2 per cent. of potash yielded a solution, which, on treatment with hydrochloric acid, deposited a floccu- ent substance unacted upon by acetic or phosphoric acids, and containing 3°12 per cent. of nitrogen. _ The remainder, after this treatment, is a whitish flocculent substance ; on drying at 100° it blackens and coheres, yet its microscope appearance does not differ from the original aspect of the fungus, It contains 1-21 per cent. of nitrogen, and affords on calcination 2 per cent, of ash containing lime, iron, magnesia (chiefly), potash, and sulphuric and phosphoric acids. ‘The body possesses all the properties of fungin. The following is the tabulated result of the — si ‘Water eK 9°200 1 Resin inl diteeerto asd Ss Lé ve. 60°S84 2. Another resin with magnesia ddliphate: Pa ie > he ee 3. Resinous body with lime and magnesia ws B14 4. Nitrogenous substance with salts Lg ve 2°900 5. Oxalate, malate, and brerelig of Sees iron, &e. oe 1-058 6. Nitrogenous Santa soluble’ in n pola Peg fis ungin .., ee ie ro 9° 686 100-000 cheaieder has found that this fungus contains from 4 to 6 per cent. of a fat which is not a glyceride. He obtained from it a crystalline substance having a composition represented by the formula OHO, which he terms “agaricol.” The liquid portion of the fat yields no glycerine on saponification, but cetyl-alcohol and another alcohol together with two hydro- _ carbons, while the fat acid with which the alcohols are naturally combined appears to resemble ricinic acid ( Rep. of seg . mgd and Aerzte” | Meeting at ae 1886), | ALGH, 635 ALG. GELIDIUM CARTILAGINEDM, Guidi. GELIDIUM CORNEUM, Law. Vernacular.—Chini-ghés (Ind. Bazars). History, Uses, &c.—This substance, ealled Yang-tsai by the Chinese, and known in Europe as Mousse de Chine, Agar-agar, Thao, or Japanese Isinglass, is prepared from the two species of Gelidium placed at the head of this article, and also probably from Spherococeus compressus, Ag., and Gloiopeitis tenax,1. Ag. Banbury (Pharm. Journ. (11), WoLag p. 808) gives the fellowing account of it :—“ Under the incorrect name of Japanese isinglass, there has been lately imported into London from Japan, a quantity of a substance having the form of compressed, irregularly four-sided sticks, apparently _ €omposed of sbrivelled, semi-transparent, yellowish-white _ membrane; they are eleven inches long by from 1 to 13 inches broad, full of cavities, very light (each weighing about _ 3 drachms), rather flexible but easily broken, and devoid 3 and smell. Treated with cold water, a stiek increases greatl) in volume, becoming a quadrangular, spongy bar, with some~ _ what coneave sides 14 inches wide. Though not soluble in _ ¢old water te any important extent, the substance dissolves for the most part when boiled for some time, and the solution, ven though dilute, gelatinizes upon cooling. The substance Under notice is used. by Europeans in China as @ substitute for true isinglass, for which many of its properties render it highly efficient. That which is perhaps most distinctive is its power of combining with a very large proportion of water to form @ jelly. This property is due to the principle named by XM. Payen Gélose, of which the Japanese sea-weed product mainly Consists, The jelly formed by boiling this sea-weed product or “tude Gélose in water, and allowing the solution to cool, wires a high temperature for fusion, differing in this respect 4.4 | Se 28 a ee ae eee rs Seay + a set 636 ALGH. from a jelly made of isinglass, which readily fuses and dis- solves in warm water. This substance has attracted considerable attention in France. It was exhibited at the Paris Exhibition of 1878 under the name of Thao. The following particulars from the Catalogue may prove interesting. Various trials have been made with it in France since 1874, especially by MM. D. Gantillon & Co. at Lyons, and the Industrial Society at Rouen. The thao is prepared for use in the following way :—After having been soaked in cold water for about twelve hours, it is boiled for a quarter of an hour, during which it absorbs about 100 times its weight of water. If allowed to cool it becomes a jelly, but if passed through a sieve and stirred until cold, it remains fluid, and in this State is more easily employed than when hot. The yellowish matter which some specimens contain can be removed by boiling for some time, when it forms an insoluble scum, which appears to consist of very thin fibres, and which remain attached to the sides of the vessel. A singular property, and one which perhaps might be turned to valuable account, is, that thao jelly does not decompose solution of permanganate of potash even when left in contact with it for twenty-four hours. According to M. Heilmann, of Rouen, thao produces, in the proportion of 1 part-to 100 of water, a dressing, which is supple and strong, and which gives substance rather than stiffness to calico, while dextrine, like starch, makes the tissue drier and harder, and gives less facing to the thread. The addition of glycerine gives a dressing still more flexible and soft, and, while rendering the tissues less stiff, it communicates more body to them. The addition of tale gives still greater smoothness. — Once dissolved, according to M. Gantillon, thao will mix while hot ith any gum, starch, dextrine or gelatine. The principal advan 2 tage of thao in dressing silk fabrics is that while preserving their suppleness it” gives them greater glossiness and makes ALGH. 637 them soft to the touch. The mixture of thao with gum traga- eanth is said to be the best method of using it, Thao should, however, be used alone for materials which it is not necessary * should be stiffened. As thao is only soluble ata high tempera- _ ture, a moist atmosphere, fog, or even rain dees not affect the material dressed with it. It combines well with sulphate of copper and the chlorides of aniline and potassium, and can be used in double dyeing. It also answers well for sizing paper, &c. The only obstacle to its extensive use is its high price. There is, however, no reason why a similar substance should not be made from our common native sea-weeds, of which Gelideum corneum and Gracilaria confervoides approach omst nearly in character the alge from which thao is made. Gélose, of which thao consists, differs from the Carrageenin obtained from Chondrus crispus in its power of combining with a very large quantity of water to form a jelly; it yields ten times as much jelly as an equal _ weight of isinglass. For purposes of food, thao jelly is not quite so pleasant as animal jelly, as itdoes not melt in the - mouth; it also contains no nitrogen. A great advantage which it possesses is, that it is but little prone to undergo change, so much so that the jelly is sometimes imported from Singapore, under the name of sea-weed jelly, sweetened, flavoured, and ready for use, and may in this state be kept for years without deterioration. Of late it has been much used for the purpose of Bacteria culture, especially in warm ciimates, Chemical composition.—According to Payen, Gélose in a pure state constitutes an immediate peculiar principle, insoluble in alkaline solutions of soda, potash, and ammonia, as well as in Water, alcohol, ether, and dilute acids. One of its distinctive characters, which is quite peculiar, is that of dissolvin g slowly ina very small quantity of concentrated sulphuric or hydro- _ ehloric acid, which it colours brown, forming with one or other them a brown compound, which gradually solidifies, and Which resists washing in cold or hot water, and even in caustic 638 ALGH. alkaline solutions. This new immediate principle cannot be confounded with any other. The ultimate analysis of Gélose presents the following results :—Carbon 42:77, Hydrogen 5°775, Oxygen 51:445, As it has not yet been possible to form with . it any definite combination, from which its equivalent weight or rational formula could be deduced, it must fer the present be ranked among the immediate principles having oxygen exceed- ing the proportion necessary to form water with the hydrogen they contain. Gélose differs from animal gelatine in not precipitating tannic acid; from starch jelly, in not being rendered blue by iodine; from gum, by its insolubility in cold water, and its great gelatinising power. From the mucilage of Chondrus crispus, named. by Pereira Carrageenin, it appears to differ chiefly in its power of combining with a great amount of water to form a jelly, which is not the case with Carrageenin. . GRACILARIA LICHENOIDES, Give. : Fig. —Benti. and Trim., t. 306. Ceylon Moss {Fng.). Hab.—Backwaters of Ceylon. The plant. Vernacular,—Chini-ghas (Ind, Bazars), Agar-agar (Ceylon), History, Uses, &c.—Ceylon Moss or Agar-agar has long been used in Southern India and Ceylon as a nutritive, emolient, demulcent and alterative, especially valuable in pec- toral affections, It has been deseribed by Rumphius, Gmelin, Turner, Neos, Agardh, and O’Shaughnessy. (Conf. Pereira’s wan eed, Vol IE, Pt. p. 19:\ It growa abundantly.im the large lake or backwater which extends between Putlam and Calpentyr, and. is collected by the natives principally during the south-west monsoon, when it becomes separated by the agitation of the water. The moss is spread on mats and dried : in the sun for two or three days, it is then washed several times in fresh water, and again exposed to the sun, which bleaches * _ it, The following directions for using the moss are given in 4L GH, 639 the Bengal Pharmacopeia, p. 276:—For a decoction, take 2drachms ground to fine powder, water 1 quart, boil for 20 minutes and strain through muslin. By inereasing the proportion of the ground moss to half an ounce, the filtered solution on cooling becomes a firm jelly, which, when flavoured by cinnamon or Jemon peel, sugar and a little wine, is an excellent article of light food for sick children and convalescents. 7 rs aie, ne Description.— Ceylon Moss is in whitish or yellowish- white ramifying filaments of several inches in length (when unbleached it is purple), At the base the largest fibres do not exceed in thickness a crowquill; the smallest fibres are about as thick as fine sewing thread. To the naked eye the filaments appear almost cylindrical and filiform ; but when examined by a microscope, they appear shrivelled and wrinkled. The branchings are sometimes dichotomous, at other times irregular. The coccidia are inconspicuous when dry, ut when moist are readily seen. They are hemispherical, about the size of a poppy seed, and contain a mass 0 minute oblong, dark-red spores. The consistence of Ceylon moss is cartilaginous. Its flavour that of sea-weed, with a the surface forming moniliform, densely packed filaments. Fructification of two kinds—Ist, hemispherical coccidia, _ containing a glomerule of oblong spores on a central placenta, _ within a pericarp of moniliform densely crowded filaments ; 2nd, oblong tetraspores imbedded in cells of the surface. _ (Endlicher.) - Chemical composition. —This algal has been examined chem- ically, in 1834, by O’Shaughnessy ; in 1842, by Guibourt ; and in 1843, by Wonneberg and Kreystig, by Bley and by Riegel. O'Shaughnessy found it to consist in 100 parts of vegetable jelly 54-5, starch 15-0,ligneous fibre (cellulose ?)18°0, _Mnucilage 4-0, inorganic salts 770. : feebly saline taste. (Pereira’s Mat. Med., Vol. II., Pt. L., p- 14.) Boo 3 Microscopic structure-—Frond eomposed of large oblong” Ps cylindrical cells, containing granular endochrome, those of 3 640 ALGAE. Kénig gives the following as representing the percentage composition :— Wat 5 we ie 19°56 Aibatiing ids se - we 2 BOS Nitrogen -free extract... edi 0 (oe Ash : 43] The authors of a Pharmacogr pha state that, ‘* Cold water removes the mucilage, which after due concentration may be precipitated by neutral acetate of lead. This mucilage, when boiled for some time with nitric acid, produces oxalic acid and microscopic crystals of mucic acid, beautifully seen by polarised light, soluble in boiling water and precipitating on cooling. With one part of the drug and 1V0 parts of boiling water, a thick liquid is obtained, which affords transparent precipitates with neutral acetate of lead or alcohol, in the same way as Carrageen. With 50 parts of water, a transparent tasteless jelly, deyoid of viscosity, is produced ; in common with the mucilage it furnishes mucic acid if treated with nitric acid. Micro- chemical tests do not manifest albuminous matter in this plant. Some chemists have regarded the jelly extracted by boiling water as identical with pectin, but the fact requires proof. Payen called it Gélose.” (See last Article.) Mr. H. G. Greenish has examined the carbohydrates of Ceylon Moss, and found that the gelatinizing constituent—the Gélose of Payen—is a carbo- hydrate convertible by boiling with dilute acid into Arabinose, and probably indentical with a similar constituent in the Agar-agar. In addition to this body (36°7 per cent,), the drug contains mucilage, starch, metarabin, wood gum, and cellulose. A carbohydrate termed Paramylan, occurring to the extent of 65 per cent., is also present. This substance is dissolved out by dilute acid, and differs from Pararabin in being directly convertible into sugar. and then yielding not Arabinose, but a fermentable sugar, probably grape-sugar. (Archiv. der Pharmacie, xvii., 241. ) The inorganic salts of Ceylon Moss consist, according t? O’Shaughnessy, of sulphates, phosphates and chlorides = sodium and calcium, with neither iodide nor bromide. oe ’ found i iron, silica and iodic salt in the ash. ee) DIATOMACEZ. 641 Commerce.—See last Article. This substance is preferred to Japanese Isinglass by the Hindus, as they suspeet the latter substance to be of animal origin. Value, Rs. 12 per cwt, LAMINARIA SACCHARINA, Lam. Fig.—Turn. Fuc., t. 163. Sweet Tangle (Eng.). Hab.—All deep Seas. The plant. = Vernacular.—Galhér-ka-patta (Hind.). 2 History, Uses, &c.—This sea-weed is a regular article . of commerce coming through Cashmere to India, and is to E be found in most of the bazars of the Punjab and Sind. Cayley (1867) noted its import into Leh from Yarkand, and Honigberger states that in his time the plant was officinal at Lahore and in Cashmere, and that it was stated to be obtained _ from a salt lake somewhere in Tibet. Murray says that it is _ supposed to come from the Caspian, and that it is used in Sind in the form of a syrup combined with a decoction of quince seeds for the cure of goitre, scrofula, and syphilitic affections. When dried in the sun it exudes a whitish saccharine substance. For an interesting note on Algin, first isolated by Mr. Stanford from sea-weed, we would refer the reader to the Jr. Soc. 3 Chem. Industry for 1885 and 1886. DIATOMACEZE. Husn-i-yusuf is composed of small, hard, white bodies, which, © being magnified, are seen to be the shells of different : diatoms, The drug is described in native medical works as Y acrid and only to be used externally as a rubefacient. It said to be found floating in lakes in Cashmere, and would ’ppear to be the same as the Shuka of Sanskrit medical » ; bene anagieanga: a WR: pagiek TETNTATT aya ged | alafersraa | END OF THE THIRD VOLUM [ARMACOGRAPHIA INDIC EN DI? TO THE 7 : PHARMACOGRAPHIA INDICA, BY WILLIAM DYMQCK, — ‘BRIGADE-SURGEON, RETIRED, __ cIPAL MEDICAL STOREKEEPER, BOMBAY, ". REGISTERED UNDER ACT XXV. OF 1867. Ms #) PHARMACOGRAPHIA INDICA. INDEX AND APPENDIX 10 THE PHARMACOGRAPHIA INDICA, BY WILLIAM DYMOCK, BRIGADE-SURGEON, RETIRED, LATE PRINCIPAL MEDICAL STOREKEEPER, BOMBAY, G. J. H. WARDEN, DAVID HOOPER, SURGEON-MAJOR, BENGAL ARMY, QUINOLOGIST TO THE GOVERN- PROFESSOR OF CHEMISTRY IN AND THE CALCUTTA MEDICAL COLLEGE, MENT OF MADRAS, OQOPACAMUND. — ZLonvon :—KEGAN PAUL, TRENCH, TRUBNER & Co., Lp. Bombay :—EDUCATION SOCIETY'S PRESS, BYCULLA. €alcutta;—THACKER, SPINK & Co. 1893. In issuing the Index and Appendix the Authors wish to state that supplementary volumes of the PHARMACOGRAPHIA INDICA will be published as material becomes DAVID HOOPER. July, 1893. Achhu, ii. 226. Achillea millefolium, ii. 271. a. oe. seal ii. 33. | ium, ii Siem bhal, iii aut »» ~ Mmoschata, ii, 272. | et ae santolina, p Ray 7 24 oars pee siees s We siting, fii, 375. A ee) 5 eee 4 e . So b> be te te be Bs Ln ee =) t= Sabie, 4 550, 556. Cacho ou, is Bees ee INDEX. ete nope iii. $61. Actinopteris dichotoma, iii. 627. gardenic, ii. 210. * Ada, iii. 420. ne lycyrrhizic, i, 494. Adaca-manjen, ii. 257 : » gurjunic, i, 194. Adaka, iii. 422 y mnemic, ii. . Adambedi, i. 4 : rdic, i, 145. Adambu-balli, ii. 536. y» henno-tannic, ii, 43. Adan-el-dubb, iii +» herminic, i. ansonia digitata, i. 218. »» hesperetic, i. 273. Adapu-kodi, ii. 53 »» hypogeic, i. 495. Adatodai, iii. 50, | isoacetic, iii. 276. Adavi-goranti, i. 242, 3) jibantic, iii. 391. Adavi- » iii, 476. is 0; a Adavi-jilakara, i Ty »» lactucic, ii. 315. Adavi-mullangi a 4 * ,» lauric, iii. 216. Ada ga, 5, lignocerinic, i, 496. Adayv: “nabbi, iii, ‘480. » linoleic, i. Ada 6. y» meconic, i. 88 Adav masakn, i 322, Sy methylerotonic, i iii. 284, Adavi-puchcha, ii. 65. s myristic, i. 195. Adavi-vuddulu, i, 491. » Ophelic, ii. 513 y: iii. 50. 99 papa. ic, ii. i Ac eli, 33 1 . A ” xy benzoic, lil. 299, Aden aloes, iii. 472. » Piperic, iii. Adhaki, i. 489. o, plumieric, . 422. £ Vasi ii, 50. a: »» polygonic, iii. 150. Adhatodic acid, iii, “53. gy: Punico-tannic, ii. 48. Adhva-shalya, iii, 136. hvaga-bhogya, i. 395. Adi, iii. 420. : Adiantum pedatum, tra; oo iti. 624. + thikboinio f eee Aaike, iii, ' Si oer sag iii. 113. ‘Ading conaifal 171. E tannic, iii. 361. Adityabhakta, i i 131. z > , iii, 284, Adrak, iii. 420, 421 erianic, li. a iii. 217, 539. agar, iii. 635, 638. k, i, 477. ili. 631. ni. 632. i-sikcha, iii. 454, -renl-pai, ii. ‘31. ui. 75. cus a chiragoram, iii. 630. 31. ‘Py, Fe, Pe Se Be fe fe fee fee fe Se 8: ee fe - INDEX. Ajmod, ii, 121, 122, jowan, ii. I] mach ramepitys, il. shed iis 27 ranadi, 1. 53 / kanda, ii. 428. karakarabha, ii. 277 karkara, ii. 277, 283. karkarha, ii. 27 karkaro, ii.:277 kasa-valli, ili an kas-gadda, ii ashgarada-gedda, ro 90, kash-~ caer is Be a beaks: aks Pcs hemes Wek cs rsa, fis eas ew es So he ck bee ee Ee bal wy al . Ee ce qi ny , us crot, ili, 2 278. kshate-che-khor, ii. 368. hy bp ye SP nee ee / ‘ é Pan ey : 4 oe ; . inks procera, i. 552. ; “s stipulata, i. 562, ¢ 563. Alei, i. i. Alen, it Aleurit rhe Moilugasn,3 lii. 278. Aleurites oped iii.-280. me mo na, i. 564, iii. 278. Aleurone, i : "307. Alexandrian laurel, i. 173. Algee, iii. 635. Alfazema, iii, 93 Algoul, i. 418 agi camel , 3. 428. > Manna, i. 418 >» . Maurorum, i. 417 moron i, 418. boufier de Benjoin, i ii, 369. Albhivia, i. 239. ieee ii, 417. ” sativum, iii. 4 : akagetartn, & Hii. 492. - Almirao, ii , a8. ee: 4 £ > the b> be fee ee ee bes. fa ba be ee ee ee ee Fy) Be, Be INDEX, ery Alysinrpus paper SAT as Am, i. 38 SB SS8888 8 8 BES Bae E B be z 2 She i a Am-ki-chhitja, i. 383. kad, i ii 39L. fe PeOPPEEPEEE Ba ete * 1 ‘i . aie a ee ¢ : Bon ) eae & BoS 2 fe) r= fake al i=% 48 ae B: eo N iberina, iii. 442. Amoora Rohituka, i. 340. mora-amari Amorphophatin campanulatns, iii, 546. Ammi d@’In D>b>b>b>b>pb>pr>bpbpbbbbppb b> er 2 ey co vo) on nacardi veh ‘Cocidental, i. 385, 548. lus Pyrethrum, ii. 277- arvensis, ii. 345. Anaighalis, ii, 345. eae 2 te b> b> b> bp ae wee inarya-tiki, ii. 511, sa-puvvu, i. 39, —. baa mitts - oad. \nasphal, \nastatica ‘fierochanting, i; uz. \nati-pandu, iil. 4 nchancha 81 Pbrb>pPr>p>b>>bpb>b>b>>>bb> >> b> bp : B Be Ef B A Jadishaw Andrographis emai iii, “aT. sine ge ‘ pa Andropogon rime iii. ns, iii. og Se enna, iii. "587. Anemone obtusiloba, i i, 38. E. ay 52 Pee 6 Anjudan, ii ii. 143, he fh « B a cr ag e-galu-gida, iii. 34, \nogeissus Tatifolia, 1. 553, ii, 12. inonace, i. ton \nona squam. sa, 1. 44. pleura esi. i, 381. intala, i, 368. b he be eS vag tee 2 fo ge * 7) a : ick wes 7 ‘INDEX; Appo, i. 73. ; Achiliga Agallocha a, iii. 217. ccensis, iii. 217. Ara- bevn See Arabian Gost li. 296, rrh, ‘i, 306. 527 162. », Guilfoylia, ii. 162. 9 eee -ginseng, ii . 162. ii. 162. ee a) me Lrjun, ii if; \rjuna, if, 11, iii, 287. li. 429, : 544. Arani(s (Sane for Breynia rhamnoides); aoa. i femtak--, s-i-pardah, ii. 560. ee pa ‘rusiman, i ii. 604. te a 249. irvore im notte, ii, . 376. \rwah-i- -kunjad, ii i, 29. nee atiyat, . 90 le ba~€ po iii. la, ii, 141, 37. :* fa Ef ‘chambar, j. S11, “rah i. 464, li, 16. Ascle de Curacao, ii. 427. epiade | Asclepiadin, ii, 428, Asclepias curassavica, ii. 427, ny echinata, ii, 443, < geminata, ii. 451, Asclepin, ii, 428. | Asclepione, ii, 428. Asfar-i-bari, ii, 306. Astrak, i. 23. Asgandh, ii. 566. Ashkhis, iii. 2 : Ashogam, i. 507 : Ashok, i. 507, Ashta, iii. 345 Ashtavarga, ii. 390, Ashti-sandh i362. Asmarighna, . Asok or Asoka, i. 507. Aspalathus indicus, i, 411. Asparagin, iii. Asparagus adscendens, i iii. 484, ‘ inalis, iii, 486. 7 sears iii. 482. = sarmentoous 5 ii, 483, Asperag, i. Asphodelus faeces: iii. 479, rach, iii. 626, Asplenium Cete falca ree iii. 6 parasiticum, i iii, 625. Assalia, i. 120. a ¢ ES BeO Be ee a 3 Atarusha, iii. 50. — lee vakha-ni i-kali, i i. 18. 6. ag a a | oe 2 a | le al oO . Ati maduram, i. 491. Ati-parich cham, i i. 343. At h-picchila, iii. 467. + \ti-vadayam, i. 15. a mamidi, i iii. 130. 5 yo Lt 148. Atti-tippil e, Yi. 543. Attie-vayr, iii. 340 tannie, iii. 340. 5. as ene angam, i. 019. veral-yennai, | L 519. rohasiyin, iii . 339. INDEX, paren ie i. 322. | ii, 6. Az ingens ram, Azima tetra rant, ian j Azmalus, Axsaoscl ens iii. 622. Azulene, ii. 276. bachi, i, 412 306. Bac Siioe chet, i. 451,. Badha mon Gee for seer a Lakoo- ee ed, ii, hae 4. INDEX. accra ye Balilaj, Seon a ant i. 304, Baliospermum axillare, ii. 504, iii. 311 Bal-kurai, ii ‘ Balli-muttaga, i. 458. “Ballota nigra Baleng 82 alara, ii 5. Balsamier le la Mecque, i. 315. 3 Balsamedendron Berryi, i. 314. Mukul, i vi dort 312, 314. i. 313, 5 ex a bangiil TOLL. otranum. i, 306. Balsam of econ i. $15, 317. alusit Bal Sai (Sin. for Persian var. Acerus las amus), iii. 539. Pag al-vekhand, iii. 539, ama, iii. amanhati, iii, 68. mba, iii, am boo, iii. 586. ! usa dinacea, iii. 586. an< an-jol, iii. 76 an-kahu, Seed feed ed bed an-tam pais. Ls an-tepariya, ii. 561. ana, ii. 320 anad, ili. 4 anafshah, i, 140 anana, iii. 445. anawanti salab, iil. 387. ndakpushp, iii. 230. andari, i. 371. andaru, ii. 193- sandhuka, i. 23: andh i, i 336. ane i-murududu, i, 16. a andri, i. 3 fandrike, i. 371. 10 INDEX. oon tg a i. 368. Bapaia- pena ii. 52. 7 peas . 237, ii. 126. ii, 338, Bare: -sehun: d, iii rgat, iii. 3 Sateuad, ii, 518. Barhal Csitad: Syn. for A. Lakoocha), iii. 355. Barhang, iii Becks ai hess iii. 313. 57 Barik- moth, lil. 652. Barphali Barrin nade aiutivigiil in, racemosa, ii. 18. Barsawashan, dit. 364. i. 354 “ 43 long, ti 355. assorin, i. Bastard tpecacuanha, ii, 427. Sandal, i 242. INDEX, Benzoin, ii, 369. Siam, ii. 371. Suaathk, ii. 372. Benz oylaconine, i. 5. Berbamine, i. 68. Beberidew, i. 64. Berberine, i. 67. : Berberis aris bed Betle leaf, iii. 183. jis DEB »> Dut, iil. 522. »» pepper, iii. 183 »» phenol, iii. 191 @ -bevina, i. 330. “9 agg 1, i. 310, 312. Bettada-haralu, iii. 274. alnoides, iii. 359. - attra, iii. 359. Z 59. idanj J He iF | or Bod -icsadah (Persian | Bevi ara, i, 323. eed Salix Cap rea), iii. 364. Bhadra-kashtha, iii. 380. : a-muste, ili, 552 te 7 - 3 . nga-cha-bi , iii. 319. mea iii. $19. aku, iii i. 319. q kand, ‘d hat, iti, 79, 601. 12 Bhatkatya, i ee a il. Bhaulan Bhava, i Lm Bhavan-bakra, i. abr ge Pa i. 432. Bhela ‘Bhends or Bhendi, i, 210; 233. Bhengra, ii. 266 INDEX. Bhuta, iii, 57 g. : Bhuta-kesi, ii, 233. Bhuta-pala, 1, 345. Bhat n-kusam, iii. 287. Biba. i Bibla, i pre i. 534. idari-n: ma m, iii. 250. Bidenguebine, ‘e ea 367. lkhi. iii. 3 Bihi-danah, i. 579 § Bija, i. 464. om beige i. 269. — 464. 5 Bijhand, ith 148, 158, Bi Pikth-bunafshah, agg 45}. é _ Bikh-i-wala, iii | Bikhma, i. 18. ee nese of, 4. 19. Birdlime Bists-cve Gh, i. 562. - 878. mi or Brahmi, ili. 374. Birmoya, i i. Bish, i. 1. Bishakpri riya, i. res Is aes 480. Bishi, es 2; Bishk ay ii. Fo 152 Bihar, Be Bishma, i cumin, is “98. de colpane, i. 320. coule 504. lonpe, 64 i 361. ‘ INDEX. Bois de sureau, i. 364, fe: 629. ,, fomentarius, iii. 630. 444. Bombax re Maiaber, reed ma “aida Lf 215. Rowiey bes 198, mastich, i. — Boneset, B ga Bombs alli, i ‘ii. ? 298. Bha au-Dajiana, i. 298. reana, i. 298 Boucerosia ii, 458. Bouillon “ey ili, 14 Brassica juncea, i, 123. i ” ni " 1220" Brazil cherry, ii. 562 ” 1.501. Brazilin, i. 501 rnold ii. et 7. ruguiera caryophylloides, 1. 599. Bryonia epige 42, ot ii. ne opin culycnam, i. 590. ryoretin hanania sintifolia. i. 394. lantain, ii, 134 88. ig (= -a--5-A-n-e-) x 4 4 B feed bowed feed feed fered beeed beced Ieee! b INDEX. Byakura, li. 555. Byalada, i. 281. Bysabol, i. 310, Cabuli-mas taki, i. 3 trifoliat: Cadi- cartes ar fi. 316 ener te ag Ceruli acid, i oes Bondi, : 496. $3 me at * 505. Cafeie er, ii C et ii. 90 ris, ili, 114. Calamus aromaticus, iii. 539. 532. Calebaasien, i. *218, iit i. 24. Calen seen ree iis, ii. 322. Californin Calli i, 60. Caltiarpe faux Tacamahac, i. 173. Calophyllum inoph: lum, i. 173. ei tomen “s tee am, i. seh 559. Oo Sa ee ee Camomille, ii. 274 a Cans 5. ” erfo liata, ii. matt ’Cardios Cardol mse, i. 39¢ ospermum Faaebeat . 366. . 388. Gastics nutans; ii, 322: Caryoph: i. 23. Garyophylus aromaticus, ii. 20. sculenta, ii. 50. ntosa, ii. 50. Cashew-nu iD; Casse Canéficier, i. 511, batons, i. 515. 16 Castor Leer iii, ae feaiics ofuisatifla, iii. 357. steppe ii techin, i. 55 EARS E 537, ii £2; ‘atec nni nic acid, i, 558, iii, 363. athartic acid, i. athartin ae airenbag thon i, 528. arene 137. ayenne pepper, ii. 563 ay-boi-boi, ii, 525. ay-khuc-khae, iii. 500 aythuong i. 5 Cece, i. Cedratier, i. 2 Cedrela Toons, i 339, rus Liban tke, iii. 380. Celastrinez, i. Celastrus p spacer i, 343. Céléri, i il. 122. Celery Cclecy: rived Sten i, 38. “aeariay 39. 627. Chatl-flower, iii. rg Chai, i. 177, iii Chaina or Hanphal geen = D. sativa and D. globosa rene , lil. Chakota, i. 370. : INDEX, ae8 hamezlea, 1. 224, = hanoti, i i. 450, hansar, i, 120 hanu-pala- vita i. 523, hanvr PL Se ay ae a ee ee ee ee eee ee ee { havel, ii. 545. havicol, iii. 189. ha -mungri, i. 142, haya, haynta rashiakoo, li. 103. bay root, ii. 1 uali¢ : hedu-bira, ii. 8 ii, 3 heiranthus Cheiri, i. 130. heluppa-maram, i. 345 hemanti, ii. 277. henai-~bol, i. 307, in i en i a a a a ak s tite i. 561. i, 85. ried Pap e: 2. BE. RE Hae okrassi a aac is 339. ‘e : Bes : E e © eS. 2 waged é or S E at — ‘4, ghauza, iii. 510. »» nova, ii. 37 » pagu, 0. - Chirauli, i. 394. Chirboti or Chitbatl§ ii 561. Chirchestite, oy [ee] hira, ui. 135. ~~ N em e n o + Ee Ee ch ct 5 ce i Be "§ Pet aie Ste ho > a . ES kshu 123. te pairi, | iii. 123. hitra-tandula, 1. 367, ii, 349. hitrak, ii. 329. hitraka, ii. 329. tri, ii. 329 a, ‘oleleleolel@ls ie. i ee fe hivaka-vera, i ii, 527. Seals Goalie sioner on Ja gt iii. 316. hrysanthemum Coro. ee ee eee ee ee ee ee eee ' ' brysarobin, i re hrysomela, i Chrysophanic aia i. 505, iii, 156. i ag i381 Ch a, iii. 287. 222. Swictenia, i. 338, 548. . 500. narium, ii. 276. INDEX, Chuvanna- mae ii, 414, Chy. oo Laney Chynle Gicendia hyesopitalin, li. 515. Cicer arietinum Cichorinm Tntybus, ii, 311. y Cigue, ii, 110. Oimicifuga: iota, i. 36, mosa, i, 36, Cinchocerotin, ii. 189. Cinchol, i Cin cheke Catisaya li. 174. vi Isa, i. 19 $5 acetate. ii, 174, 34 officinalis, ii. 174. res succirubra, ii. 174. 3 aloids, ii. 180, 187. ee 5 Lees Cinch, i 1ST. Cinchonin 180, 187. Cinchotannie acid, pe 188 Cineol, ii. cinaueus ldchy dee 3 iii. 207. Cinnamomum Camphora, iii. 199. Cassia, iii, 203. *5 iners, iii, 20 1 nitidum, ii a ‘amala, iii. 208. T Figen i, 44. Cinn iii. 2 cori i. 54, Cissam: s Pareira, i “ 53. Citric ar i, 273, 2 Citronella gra: Ci er, i. 26 INDEX. - 49 Clitoria de Ternate, i. 458. Convolvulus arvensis, 542. ove, ii. 20. : : por > Hi. 528, 8; liv 22. Coor rie ’seeds, Cheorum tricoccon, iii. 224. Goorundostis-var, iii, 313. 0 yi. 50. ‘opal gum, i. colle di Levante, i. 50. Cotine, i. 33. ‘us indicus, i. 50. Coptis dannancidiia: 1. Od~ » 1. 64. jy Deeta, i. BI, villosus, i. 57. eet ‘ knead iii. 396. ee e de were? ii. 50 Coquelicot, i 1,151, | Goqueret or ‘Cogerll, ii. 560. 3 riloculatis i, 236. Corn Se - 08. silk, ili Covisents, i “Cornos das Diab iii. Pay Cornutia corymbosa, ili. 67. Co-roi-ngua, iii. 60. its speciosus 427. Cotoneaster eet i. 583, da Wavesin, < i 119. 20 Cressonée, iii. Crinum asiaticum, ill. 464 zeylanicum, li. 466 Crocus scott iii. rossandra andulaefoliay i iii. 45. Crotalaria are 1. 401, rc a, i. 400. is Detiague, i. 401. % retusa, i. 401. ” sericea, i. 401 Croton catharti ique, iii. 281. oblon weifolias, 4 iii. 286. 39° OL 258; Tig m, iit. 281. Crotonic wid a 284. Crotono Crotonoleic aod, iii. 284. Cruci =e tocoryne Spits i. 18, ili. 548. Cryptopine, i. Cryptostegia grandior, i . 425. aes minor, in. 403. iii. 406. INDEX, 3 Cuscuta hyalina, ii. 548. 4 Be 1 aniflora, i li. 548. ‘a reflexa, ii. 648. ne Es Cylista scariosa, i. Larrea aoifotium, ees vatum, i iii. 3 tenuifolum Hi 836. Cymene Onan ii. 115, ili. 566. ii. 443. ii. 554 rotundus, iii. 552. Dabeli, i - 207. Dabi-duba,' iii. 510. Dabra, i. 427. Dabria (Bomba. 7 aaa for Avogeeiond aioli : Daathy or Kash for — : rice Eynosaroides), 4 "BIB. Daé sin ie 4, 2913. ne: hiphala, i. 982, : INDEX. 2} Dalbergia olubils i. 461. Dasamuli, i Dalchini, operat a Dalik, i. 574. a Datir ( Vern. fee Has gibbosa) iti 347. Dalika, ii. 81. Datisca — ii. Dalim, ji. 44. Datiscee, Dalimba, ii. 44, rasernragd it eae Dalimbe, ii. 44. Datturi, Daman- papers, ii. 197. Datura faatuosa ii, 585. Damask rose, i. 574. Met sre 585. wain, iii, 504. Stramonium, ii. 584. Dam-el-thuaban, iii, 505. Daturie ania, e ii. 588, m innin, iii, 505 Datwan, iii "O64. Datyuni, ii. Daucus Carota, ii. 134 an-hoi, i. Davala, i. 426 si 12 , li. 508, iii. 282. Dey nighishnde, Li. 572. Debrelara Deek, i. 386 Deishar, i. 208. elphinine, i. 39. inium altissi rae ot , poe RP i, 37. ” i. 37; ty deonudatums, i i, —s = 400. Ue: ’ i 23, ii Dendrobium macraei, iii rf ies ii. 811. Deodali, ii. 81. dangri, ii. $1. a Deodar, iii, 380. » Hi. 356, -ki-lakri, iii. 380. iswak, ii, 381. eokapas, i. 225, ; 1. 880. Deokeli, iii. 449. li. 431. * | Deonal or Dahavala, ii. 322. ariya, i. 562. Deotadi, ii. 81. Derris uliginosa, : 470. Desert date, i. 28 Desmodium gangcionm, i i. 428. triflorum Deva-kadu, ii. 502. De 22 Dhan, i iii. 601. Dhana, ii. 129 d benvnan- gest, ini. 10. : oer, 129. INDEX. Dinduga, i i. 17, ling resins _ soe soliag li. 340. Dioscorea aculeata, iii. 551. Dioscorinex, i ili. Diospyros Ebenum, ii i Em mbryopteri, ii. i. 366. ’ aki, ii. 369 ay montana, ii 368. Tupru, ii. 368 pushpa, i, 42. Diplospora a i. Ceara ii. 125. ipterocarpez, i. 191 Ni Mere < alatus, i. 191. incanu: i, x Dodda-mar me et 63. Do ri, 4.201. Dodonea a i. 371. 371 Doduchallu, i ii. as Dogbite shrub, Reema Fare m i, Bhi Dorema aureum, ii. 160. " labrum, ii. 156, or; nj, li. 568. Dor. ih ins “ Doroni ic, Doronicum patalinnches li. 292. © amer Dou meat ii ge Dowalah, iii. 628 Downy Grislea, ii. 40 Dracena, Gi ape iti. 604 antha, iii. 50 16. Dragon’s Neate wa 504, 532. nzibsr, iii. 506. Drakh, i. 357, Drakhya, i i, 357. rakhsha, i. 357. 5 arishta, i. 357. » pandu, i. 357. rakshi-hannu, i. 357. ramahui, i. ravidi, ili. regea vali, ii, 444. Dregein, ii, k, i. 3 Dridha one iii, 514. roga amara, iii. 47. =o alanops ae i, 197. Dub, iii. 577. 3 2 feat) dies . pt Me, @ fas * = Metal or Dagaa, i ii, 457. ugdha, ii. n el-f faghiya, ii, 42. hn-el-car a) ee 43 Fee f . B ee & . . is nr ~I ha chant hemp, i, 213. ku, ii, 126, ’ INDEX. ; 23 Dulaghondi, iii. 313. Dulagondi, i. 447. Duleamaretin, ii. 554. Dulcamarin, 4 Duleamarine, ii. 554 Julingi, iii. 400 Dummaala, i. 7 Dupada, i. 196, Durah-i-kizan, : ee ’ entities iii. 5177. Jusparsha, i. 246, Dush-pradarshani, ii. 557. Dushta-puchattu, i, 374 D cadens ii. 442. Dviparni, i. 351. Dwale, i. 512. East Indian Elemi, i Ser et 4 1231, Eau d’ange, ii. 34. Eau sucrée, iii. 595. Ebenac ee, ii. 366. Ebony, ii. 368. Ee sa (ate Elaterium, ii. 95. Ecbolium Linneanum, iii. 49. Echites scholaris, ii. 387 Ee ry eaonte ny, i 389. Echicerin, ii. 389. Echinops echinatus, ii. 320. Echiretin, ii. 389. Echitamine, ii. 390. hitein, ii. 389. bitin Ecli Ecorce de codagapala, ii . ool, >> 9) Jantour, ii. 374, Eda, iii. 505. Edah, iii. 506. Ei ees Eejin or Eeyin, iii. 574. Penthakai, iii. Egle Marmelos, 1, 277. tian y 4 10 myro! ; Fhretia buxifolia, ii. 52 24 kharo, iii, K- “Kanda-istn lil, 492. a 28. Ui eae By ar ea a ©, OR ae a to (e7) = Bt on 2 = (=) 5 oy ‘3 : . nt i) fo: Ses 2 ro oa _ On Flom! ( (ast naan) .: 321, Elephant oe — sinner ii. 243. Eletta: omum, iii. 428. Eliya, ini. 467. Ellago-tannic acid, *iii. 263. Ellu, iii. 26. Elm-leaved Sumach, i. 372. Elumich-cham- eres i, co pase sen tolashi, iii Elwa Embelia Rites: li, 349. ee robusta, ii. 350. Emilia son chitin u ot Emodin, i. Dong Ensal, iii. 4 Eistade pursetha, j i. 539. _ _ scandens, i, 53%. ‘iii. 560, INDEX, Eraka, iii. 538. Eranda, iii. 301. Erandi, i iil. d0l. Erando, iii, 301 Erem a labios, i lii. 404. ang 4 Ericu, Sue Veen asteoides, in. 251. nadensis, i Be 249. Erima- ‘pana ~ 16. Eriodendron anfractuosum, i . rapa J (i, Jom ndha ae che = ine, i, 454, 7] rythreea Roxburgh, m1: 517; Brvt ina rss Vv % monog yams, i, 242. ; iii. 1 q ae Ola, ie . 210. esh, i ake ally i 126. Esopgol, iii. 1 _ Espinho es ladrao, i. 260. oa se . Fang ii, 27 2. . 190 Eulophia ¢ cmpostris, iii. . 385, 388. ‘3 nuda, ii 8. ree i i. 389. Euonymin, i, 347. moe nipoe oe Pe i. 347. ndulus pe Euphorbe antivenérien, ae Euphorbia ro re antiqu oa a 253, 261. S clarkeana, iii. 250 * Euphorbia gg ye iii. 256, Euphorbiacer, 247. Euphorbic acid, i iii. 259. orbium, iii, 257. Feil Oteand pampin on vitis, i. 358. Ezhilaip-palai, ii. 386. Faba marina, i. 540. ‘Pex vini, i. ys eee INDEX. Fe Ferula ovina, ii. 139 bed a Féve des ¢ champs, i j reves ma hg Cy he $80. t. Ignace, iis 500. Fil Filfil South, i i. 563. i li 4 ‘ Frutex x glo obuloram, i, 497. Fudanaj, i iii. 103. ‘ / 96° ee a — iii. 104, ae iaticum) , iti - 23, INDEX. No ronda ili. 440, um, ii. 154. Gale men ea, i, 415, Galkakckas pata, ili, 641, 41 Gali, i anajali, iii. ; Ganajali-kullu, iii. 163 anasura, iii, 287. ao aa i, 262. Ganda-puro, ii. 325. Gandah-hine cna i. 302, ii. 158, i iii. 378. i ( r Gan eas . 163... Ganiha/bhadaliya, i 299. Gandha-bhaduli, Gandha-che-khor, iii. 232 Gandha-ga for Rasna), Ga cian umbar (Syn. for Ficus his- pida), iii. ndhada- shekke, lii, 232. Ga ( : i na, ii. Gandhani, iii. 163. G 3. ( n-chekka i ii. 232. ( 557. ( ranja-pal, iii. 319. anja 1 (Syn. for Cannabis eek iii, 318. Ganja-rasam, ii. 319. o INDEX, pee Ganje-rsham Sem. for Cannabis Gazmazu, i i, 160. sativa ee oar iii. Gebokanak, i. 588. - Ganja-vir 319. Gech- i Pearce vty iii, 319. Génepi blanc, ii. 272. Gengeli, iii. 29, ‘ Gentian, ii. 508 Gentiana Chiesa, ii, 612, Dahuz ii. 508. Gharbi ( Syn. for Datura tura fruit said imported from Persia), ii. 5865. G -naru, ii. 92. giarga iii, 631. 28 naan iii, 149. hati-gum, i, 554. hati- mirchi, i. 654; hati-pitpapra, ili, 49. vum, iii. 607. hebu-nelli, ili. 66 helegherinta, i 40 0. heru’ utti- amma, ii. 243. hi uli, it 30. De ee Oe RRO RR RCE E EES . = ia ' aH ~. 5. Gingelly oil, iii. 29. ' Ginger, iii. 420. , iii, 567, . 20. Gi roflier aromatique, ii. 20. Girenniera reticula ta, iil. 316. Gisekia a ioe. ii. 105, oie 1 Gith, i rE 2. Gloiopeltis tenax, iii. 626. Gloriosa superba, ii Glossocardia — INDEX, Gobhi, ii God’s sooty iii, 629. 9. Gojia- “lata, ii, 244. Gojibha, ii, 244. ”» en }) ie 26 ae lahan), i. 248. - Sars i. 243. Gokhuri, i Gokhsura Golden Clainp, 1. 42. oe ollyrium, iii. 499. ii. 247 Gopi- -chandan, i i, 108. Gora-bach, iii. 539. Gora-limba, i a Gora-nimb, i. 262, 330. Gora-tel (8; yn. for sweet oil of bazars), Girecwuels or Bach, iii. 539, Gorae 8. i ae alas OE Re Sas Sets, est i. 365. . 388 Grac Grain d’ ambrett tilizefo. ? aria hemody, iii. 688. se sabrophyil a 203, 238. ” 237, 163 INDEX. Guizotia abyssynica, ii. 269. tujar, 1. 476. u oe i, 576. ulabi-huvou i, 574. abi TLUVOU, Mt =: © 6 — i =] © = a --h-8--- 0) - 2-2-2 ‘3 5 5 ag ry = # = e - B = a S on ~~ On ~ -i-ghafis, ii. 508. -i-pisteh, i. 380. tura 06, L an i ee gk eg ya 4-5-4 -A-5 4-8-4 ahs : : EES 2 oo =~ = p st > =a Li) a = > wo = ~) oe ro <) oO », Bassora, i. 565. ed poe are te ii. 369. ee yy Indian, i . 644. Crunnanseieey iii. 70. 80 INDEX, sy Cai (a grass like Suna), iii, | Hab-el-sanaubar-el-kibar, iii. 379. d u dis t20; ( aie: Hab-us-salatin, ii. 504, iii. 282. Gunta- F Sivers: li. 266. ab-us-sauda, or souda, i Gunta-kalagara, ii. 266. ab-us-saudan or sudan, i. 524.. Gur, iii. 597. Hab-el-zalim, A ‘ Gurach, i. 54. . Habenaria sp., 7 Guragi, iii. 437. Habhab is Habhabu, i219, a Gurige, iii. 268. Hadak Gurugu, iii. 139. i fades 133. Guraku, ii. 636. adha-naeptanam, i ii. 158, Gurbiani, i. 33. | Heemarago, ii. 49. G ss aes Ye Haer, i Gurgal, i. 117 Haft-barg, iii, 225, Gurgiyah, iii. 563. afuz, ruri-ginja, 1. 430. agala, ii ( urjo, i 54. acenia abyssynica, i ; 570.. : Gurjunic acid, i. 194 Haie Nae i. 505. 5 Gurka re: ii Haj, Gurmala, ajar eal ukab, i, 498, ( arati-ehetin, li. 442. akano Abura, iii. 104, Guti, iii Hakkarike, ii. 244. { atta ‘Giese S . 173. alad, iii. 407 Guttier des peintres, i. 168. aladarava, i. 338 Guttifers, i. 163. aladio-vachnag, i. 31.. Guvaka, iii. 422. alahala, iii. 400. Guzhad, i. 476 aldar, iii. Gwal-kakri, ii. 73. aldi, iii. 407. Gwan, i. 377. aldu, ii. 17 Gwid, iii. 227. alicacabus, ii. 560 G sylvestre, ii. 450. Uy dit, , Gymnemic acid, ii. 45 eh-i-asfar, ii. 2. { is pentaphylla, i. 132. alileh-i-Chini, ii. 2 Gynocardia odorata, alileh-i- Hindi, ii. 2 Gynocardic acid, i. : alileh-i-Jawi, ii. 2 Gypsophila Vaccaria, i. 155. Halileh-i-Kabuli, ii. 2 j 3 Struthium, i. 156. alileh-i-Zangi, ii. 2. . Halile Zirah, i i. BZ. q Halim, i. Haliyun, iii 486 Ha iii. 10 Halkasa, iii. 123 Habak-hadi, i. 310. Halmadhu 2. Habak-i-Kirmani, iii. 83. al-mekki, ii. 65. Hab-el-aas, ii. 32 al ; Hab-el-arar, iii. 371. Hama Hab-el-arus, iii. 180. amamelidee, i. 593. Hab-el-asfar, ii. 308. Ham Hab-el-balasan, i. 316. Hana, ii. 1. Hab-el-fakad, i. 475, iii. 76. . Hande, iii. 549. Hab-el-ghar, iii. 214. Hansraj, iii. 624 Hab abashi, iii ] yal Ha ykanaj, ii. 570. ahmar, ii. b-el-kalb, i. 390. Haplanthas tentaculatus, iii 47. Hab-el-khatai, ii. 504, iii, 282. : verkiaitintas i iii. 47, b-el-kulai, i. 448, Har, i ii. 1, 376. “ lahv, i . Ta, ll. 1. Hab-un-nil, il. 530. ii. 263. Hab- i. 209. Harade, ii. i. larala, iii. 577. ae iit. ° er Bony we oo i. 225. % Haya-puchchha, Asva-maraka. zar-banai fi i491. I Hedge mustard, i. 121. INDEX. . 31 Hedu, ii. Hodychium spcatom, ili, 416, 417. Heggurutike, iii.2493. 7. Heil, iii. 43 Hejakiyus, ii. 430. Hejurchei, iii. 125. ins leean: He Hela (Bauibayg ‘Syn. for T. belerica), Helenin, i ii, os Helicteves. pel H aie se m. becifliamy aw — waldi, ii. 526- wv wv 5. open - ag undulatum Helxine 542 Hem: apushpi, . 462. Hemidesmus ee ii. 446, ee ote Henno- tannic acid, ii. 43. Herb Grace, i. 251. i. 249. Herba admirations iii. 124, »» doce, ii. 132, $5 insane alba, iii. 266. ” ” rubra, 2 », Scheenanthi, iii. 55 », solaris, ii. 526. ay ark hirsuta, iii. 427. mphoniaca, ii. 626. et * bone, di . 244, cousin, i. 238. iii, 5 iit iii. 124. Herminic ac acid, i. 255. 32 Hermodactylus, iii, 495. Herpestis Monniera, iii. 8. Hesperetic acid, i. Hesperetin, i. 273. Hesperidin, i. 273. Hete Sadi (a Roxburghii, iii, 24, Heuber, itis ‘Abslinoschins, 1. 209. i esculentus, i, 210 populneus, i $9 Rosa- -sinensis, 1 204, 5 Subdariffa, i. 212. tiliaceus, i. 228. Hijja, i M17. Hijjal, ii. 17 ijjala, ii. ijli-badam, me (Mahometan on for Cardamom), Hil- bawa, i iii, i 436. for nna, Hinne’s-koreish (Arabic Syn. Charela); iii. 627, mon (Syn. for WiGaskios littorale), Se eat i. co i 8195 3 Hiranpad, ii. 642. INDEX, Hirva- Capa ot it. 564. caulina, iii. 406, ada Hol lnmen aniidysonterea i 3agt. Holingi, Holly- eaved ce nthus, iit. ele Aart ie gece Ag ee 318. 457. oya quiabilie— -see Dregea volu- bilis Hrasva- -pancha-mula, i. 244. Hridayarnavarasa, ii. 549. Hrivera, i. 224. Huang-hang, iii. 153, Hucha-sasavi, i. 131. Hudai, iii. 20. Hugonia Mystax, i. 243. Huile amére, i. 214. », de badiane, i. 40, Hulhul, i. 131, 132 ulwa, iii. 38 Hum, Huma, iii, 369, Humula, iii. 41 Honase, i. 53 Hura, iii. 314 Haurf, i. eo Hurhur, i. iii. 501, 131, 132. Hurhusie, i. eit 132. Hurina -shook -china, i Husrum, i. 358. Hutchati, ii. 269. me Huziz- 2 Hyduocarp 7 aed... ie) 5B oO cay Bachem iii. 159. preg ii, 423. u, iii. Hetiead, i, 243, ili. 36. INDEX; aera aie (sweet), j ii. 397. Indhana Indian a ier t n ai serowvot pa 2. bdellium » bi acy », butter-tree, ii, 355 17. COEN, ik. 37 vy costus, ii. 297 ‘s emp, ili. 318, ‘ 0, 1. 464, 4).- slag, at S22. a et 65 2 persimmon, ii. 366. 3, sarsaparilla, ii. 446 », Shot, iii, 449. »» Spinach, iii. 14 », squill, ili. 476. », turnsole, ii. 525 ild uine, i, 362. pe aihoides, is oe la ig ai ae ai Enola 406. trifoliata et 412, Tndigotier = i. 406, In 7s see idi pers i. 139. Ipeca du pays, ii. 439. 33 34 Ipeca pays, iii. aie >», Sauvage, ll. 439. — anha bane, ii. 427 Ipoh, ‘tii Tpomzea aquatica ii. 540. biloba, ii. 536. country), i. 333. »» uniflor vitifolia i i: gees Ippa- chetiu, ii 355. Ippa-gida, ii. 35 a germanica, iii. 451. irk-es- -sus, ce 492. Trojappu, i. na Tron-wood t : ban Pg , 1. 170, ii. 34. INDEX, sohesperidin, i. 275. sopelletierine, ii. 49. 6. 6 back teed been b Do vay eu ~ SRE GEE: a ee gee or e i iv) . ot A ai ae ie! Ixora coccinea, ii. 2 2. », parviflora, ii. 214. lii. 558, -i-jami, iii, 572. Jack- ha ge Hi. 355. 4, Tefarabad oe i iii. 467 2 2 sy 4 Cy Cy Cu Serres eee epwaer ree eee “ je Se i: ce ee + _ Sr: is 7 aE oF fad Cy Gy Cu Gy Gy Cy GO 6 et, eC e186 ani, ii, 82. ariyamed, il 373. asaya, iii, 550, 562. pase SPREE 1 ne fee ee oe Se eee ee ae INDEX. __ 35 erany net 274. andulifera, iii. 272, rnultifida, ii 274. J ambhira, iii. 109, 69 [=~] = a B Qa eo ~ =] Cd . TI Ay oe ¢ i ° E _— =) ie) A hau, i. 160. tree, ii. 421 wide i, 160. 379. . oe 9. dh Py i irene a Thing li. 523. diflorum, ii. 378. Jhinti, iii. 43. iii. 7. ; mee de pee ih ibanti, ll. — Jibantic acid, iii. 391. ingan Jingili, iii. 29. Jingini, i. 393, @®,@,@,¢,¢,4¢,6,¢ meet eet Sk StS Os Ss Cs Oy Cy Cy Ss Ss Ss Ss Ss Se Gs es Ges Gs Gs Gs td is) jor) ntiyan, ii. 509. re, its 179; vanputra : lil, 272. ivanti n, eee ob’ tears, ili, O73; oi-pani, wots uncus od W 18, iii. 553, 562, 564. plea gC nga tig hegs li. 5653. Jung-gala, ii. ooh ita, . “148. eranium, Ha icosa, li. 49, Justicia Reboliom. 3 iii. 49. Genda: a. iii. 4 . ¥ ii, $22, » iii, 180. ii.180,° INDEX, pee . 135, Med too ada-ud at-rengay, itl. 520. ala-mara, ii. 169, avanchi, ii. 79. inge, li. 50. vea-Caravaili ge-garaga, iii. 266, Kadoo-para, ii, 319. KAadu—se . Kadu-cai-pu, Kadu-dorka, ii. 80. Vo-jiri al pene mee iii. 414, : rotunda, iil, 416. ede Syn. 563. sy Hy 272; aitha, i. 586, iii. 635. ae iii, 507. i-ilai, ii. 266. appudai-tailam, Hi 23. for Idkhir), ili. INDEX. 37 Kakara-shingi, i. 374. Kakhan, ii. Ka eros (Syn. for oil of S. oleoides), 2 eas kodi, i. 459. ‘kata-shingi, i, 374. 50. - 560, 561, ye 6 paryrute pr erg cert ‘a BESS Soe SSS see SSS pr Ss i a oe be be be be be be be be be pe ee be » os : * BE BEA oo. > E Fe : die J) 6. kulak Soteex Po for L._ temu- entum aes ti, tis. a, ii. "538, iii. 443. -adulsa, i a-ala, iii : 42 gg Fe > eS & i eS: ee ee Saf ba ow me © . u-khajur. or kirayat, iii. 47. -kura or r kuda, 397. iii, 480. 2 oe bw 2» - ' ‘ ps > E. r s we to i 24, i pai-kizhangu, ee 480. gt a ae om SS Fig a ree 38 INDEX. Kalambak, iti. 219. Kamala, i. 71, iii. 296. Kalambaka, i ‘H Vil. Kamal ni-mala, i 55 Kalambi, ii. Kamalata, 40. Kalanchoe eat i. 590. anchi-chettu, ii. 549. * spathulata, i, 590. amappu, iii. 383, Kalangura, ii. 370. d spam ~ 454 Kalapu, iii. 627. Kamazariyus, ii. 251, i "125. Kalara, ii. 255. aren ae iii, Kalarva, ii. 380. amboja, iii. » Kalavi, iii. 480 { bu-malini, ii. 516. Kalavi-kaya, i ambu-pushpi, ii. 516. Kaldera Bush, iii. 535. amela-mavu, ili ‘ Kale-jire, i. 28. Kamila, iii. 296. Kalfah, iii, 204, 208 amini, i. 265. Kalgori, iii. 20, : aminpulai, iii. 138. Kalgorn, iii. 20 amkam, ii. 370. Kali-beli-pann ravara, lii. 625. am-kasturi, ili. 83. Kali-haldi, iii. 403 amla-nebu, i. 270. Kali-hari, iii. 480 mohi, iii. 264. ‘Kali-jiri, ii. 241 amohi-jo-chodo, ii. 264. -Kali-kari, iii. 480. ° amohi-jo-pun, iii. 264. Kali-kanghi, i. 208. ampilla, iii. 296. Kali-kasondi, i. 521. Kamraj, i. 365. ali-kutki, iii, 11. Ka: , lii. B45. Kali-mirach, iii. 166. Kamugt, iii. 522. Kali-miri, iii. 166. Kamun, ii. 114. .Kali-musli, iii. 462. amun-i-Farsi, ii. 114 Kali-pandan, iii, 625. rien “I ni, ii. 114. Kalinga, ii. 392 Ka i-muluki, vege Ey Ss ngada, ii. 63. : naeviencd Vat ii. 114, Kaliun, iii. 126. i, ii, 549. Kalivasu, iii. amus, lil. 375. ‘Kaliyana-murugeu, i. 451. Kana, iii. 176. Kalkas tee ious for Alocasia | Kana-mula, iii. 178. Indica), iii. Kanab, iii. 323 Kal-kasonda, . on Kanakbira, iii. 323. " allasabatra-sige, ii. 197. Kanakaia, i. 366. Kalli, iii. 252. anakaphala, iii. 281. Kolli-Kombnu, iij. 252. anbher, iii. 394, Kallurivi, ii. 37. ako, iii. 281. lur-vanchi, ii, 37. ? cs anie mpa, i . 233. Kalmeg, iii. 46. Kanana-eranda, iii. 274. Kalmi-sak, ii. 540. Kanang-karai, iii. 509. Kalnarn, i. 590. Kanapa, ii. 17. Kalo-miri, iii. 166. Kanapa-tige, i. 365. Kalonji, i. 23, Kanaphata, i. 3 Kalpasi, iii. 627. Kanari, i. 320. Ka ead 12. Kanari, i. 32 alru, i. 228. Kanbil, iii. 297. nda, iii. 43, anch, i. 260. al-umar, iii. 346, ancha, iii. 319. anchana, i. 536. anchanara, ii. 536. Kanchara, iii. 509. anchari, ii. 322. anchata, iii. 509. anchava-ela, iii, 319. anchava-pala, iii. 319. anchaya-vitta, iii. a INDEX. 39 : Kanchi, i ii. 549, iii. 294 Kante-kan Syn. £ i ‘ . for Dioscorea - Kanchi hi-chettu, i ii. 549. sclealay ait 351. : i 6 Kanval, i pikachchu, our Kapur-bhen ai (Syn “for i ata), i. sta ig iii 414, at 3 4.0 Karanfal, ii. 21. Karanfal-i- basta, iii. 90. Karanj, i. , 468. Karawiya Ka srawivac i- dash Cai sian lps. for C. macula pried 2 ~ INDEX, Karmat-el-baida—see Hal-el-kilkil. a ketal: or iii. rita Karpura- val, ii..92. Ka oe - 200. arpushpu, iii. 426. Karrapu angen 319, i egeee = 545. arumbu, aruna, . 260, lii. , 545, arunkanam, i. 523. arun-s acti, i 28. Karva-badam, i. 563. i sige ome ii. 67. gota ii, 392. arvan, i Ivi or Karei, i. 50. sda iti. 346. iii. Site hegre: Karawiya. ete - 60. Sein “90. arwi-tamnbi, 3 ii. 67. arwi-turai, ii. ge arwi- wagetiy i - 26 asab- iii. 539 Dia bene iene fect Mica teeead Daceed iain @ Kasai, i iii. are Kasai-bij (Bombay Syn. for | ryma), iii, 573. i. 520. Kash (Syn. for hare ae Sree Kashamaram, ii. 35 -Kapur-kachri, asaghini "hee, ‘ae rh Barhanta)y Fae 6 ee ee ae INDEX, * Al | ‘ash =yadam-kottai i, 563. — i, 964. : Kashfa i, 296 tkaranj, i. 496. Kashi a wh ‘bahafshah, i, 141, Kat-morungi, i, 430. Kashshing, i » 287. d actin 1, 262, htha Kadai, ili. 450, | Katori, i ae aton-k maravara, iii. 388. Katon- shabe-massrake, lii. 388, i Eameda-che:t, 3 i. eg Kattali-papas, ii. 99. '-bhenda-vittulu, i. 209 atta-manakku, iii. 274; 209. Keel tied heal a’ tu or mts), B07 491, iii. 4 42 ” Kau. ae ii. 264. undal Trad 430 o~j}] Kaur (Punjab Syn. for Katki), iii. 10. 36 Ka, 3. Kaya aputi th kash i 23. yoo-oorb, . 252 - Kayputi-nu- tel, ii. oe Kazhzr-shikkay, i 2 "Gein Syn. for Khari), ii i eh iil, 635. Persian INDEX strings lil. 58 6. Keya, iii. 535. Khadaki-rasna, iii. 394. Khadir a _ Khadiri, i. 538. Khaya naga, iii. 480. ' Khair , 1. 559. hai barn (Syn for Lesser cards mom), iii pi hair-champa, ii. 421 Khair-sar, i. 558. Khairva, i. 511 Khaja, iii. hajgoli-che-vel, i. 365. Kha pe 313 hakar, 1. 454, kar-no- 2 or eag i, 454, h i, d 7 o = [| ee ie i. 73, iii. B71. ilaf, iii, 365. Khilaf-cl- Balkhi io Syn. for cipal it -i-Khalil Shorasan thorn, i. tora jamo, 626. Eeorasnicajowan, i 110, 626. a san am, ii, 626, “ £ ] ae = os o> & * 5 - F 5 we iS rE erg ey Sar aes a al = ao or = eed Seed eee) feed bed bere! uru-khajur, i. 332. vicar iii. 10. uru-mulaka, i ili. 166, Lactucin, ii. 314. ale, iii. 272. Lactucone, ii. 314 uruvaka, iii. 43. Ladies’ smock, i. 30. eylam, i. 556. Lagena ndra tonleata, A oh tii. 548. ia Ee 527. Lagenaria vulga anda adawan, i ii, 59. Laggera eanee 48 ii. 955. a ae . 123. saghu-khatai, ii. . mia, . 419. sagondium, iii. 74, Kurupu- ee 26.5.2 wahana-gokhru, i, 248, Kurtun, ii Lahan-khari-narvel, iii, 76. Kuru uruya—see Karawya Lahan-nayeti, iii. 250 Kusa, 575. Lahsan, iii, 488, Kusar, i. 319. ual; di : Kus avehela, ii, 593, Laiteron, ii. 319. d ushmanda, ii. 68. aitue, li. 313, Kushta, ii. 296. Laja, iii. = Kushta pets oe 20. Lajak, i. 538, : ushumba Lajalu, i. 247, 538. Kushuth or Kushooth, é aS ii. 547. Lajri, i. 247, 538. ust-el-bahri, ii. 297, ii Lakki, iii. ' Kust-el-halu, ii. 298, iii, ce ; Lakri paghanbed or ease” i, 585. Kust-i-shami, ii, 259. Lakri-rewa 153. ust-i-shirin, ii. 298. L mana, ii, ‘581. ust-i-talkh, ii. 298. Lakshatarn, i. 455 us bari, ii. 129, Lakshmi-devatya, ii. 562. usum, ii. 30 Lal-ambari, i, 212 umiba, ii. 308. Lal-b ‘: Kusumbe, ii. 308. Lal-bherenda, iii. 272 » li. 308. Lal-bhui-amla, iii, 266. Kut, ii. 296, 300. Lal-bhui-avala, iii. 266. mitha, ii. 300. La lavanga, ii. 49. Kutaila, i. 110. Lal-chandan, i. 462. Kutaja, ii. 392. Lal-chita, ii. 329, Kutajarishta, ii. 392. ual-chitra, ii. 329 Kutakan, ii. 107. Lal-chitrak, ii, 329 taki, ili. 4, 10. Lal-goachi-phal, ii. 30, Kutaruna, re Lal-ja i, 30. Kutchoo, Lal-indrayan, Kutherai-kolapadi, ii. 536. Lal-mirach or mirch, ii. 563, Kuthekar ual-morich, Kutki, iii. Lal-safri-am Kuttra, ii Lallemantia ernalag iii. 90. Kuttun, i. 125. Lalo, i. 220. Kuvali, ii. 6 Lamajjaka, iii vara, iii. 424, 467, Lumin ccharina, iii. 641, uzbura, ii. 130, uamnjak, iii a K-wei, iii. 204. : Lamka: yadage, ili. 535. ‘ jampooyang, if iii. 401. Kydia calycina, i. 228. Lompourde, ii, 262. Kyllingia mo monovephalay “ als iii. 556. Lares iin microcephalum, triceps, mpuium, iii. 401. Lang, i. 489. Langala, iii. 514. Lanka-morich, ii 563. popes i iii. 252. ‘ Langue femme, + 90, uanifera oan - Am uantho opin q i. 49 90. ‘ath yrus sativa, i. 489, 490. : Laudanin i, 88, ‘ SR asiocine, i. 88. Launza nudioulis ii, 319 imide, ii. 318, Laurus nobil is, ili Lavala, iii. 554 Lavandula Stoechas, ii. 93. Lavang, ii. 20. a-pattai, iii, 203, nga-patte, iii. 203. Db Toot nit, ii ie : febidiropis oi orbicularis, iii iii. 478. macrophylla, i, 364, 2» sambucina, i. 363. Staphylea, i i. 363. Le , i. 400. etanine, iii. 211, 213, 214, 217. 214, i. 269 snake iii, 478 . INDEX. 47 Lemon juice, i. 274. Lendi-pippali, iii. 175. ndva Leonotis nepeteefolia, i a 125. Leopard’s bane, Lepidin, ied Lepidium graminifolim, 119. I 8. opium ii. 314, Lenias aspera, ‘iii. 122. cephalotes, iii. 123. me lia, iti. 123. rs ylanica, iii, 123. Leucindigo, 10 Leucoje, i. 130 Leukoion, i. 130. Lewa, i Liane vermifug: Libadiyun or tifadiya ii, 330. Lichenes, iii. 62 Lignum Aloes, i iii, 217. Peete? £03. Ligustrum R oxburghii, ii. 380. Liliaces, ii. 567. Lili-chahe, iii. 564. ame i, "393 ophila graoloides, pits 7. ”? gratissima Limonia acidissima, i Zi 267. Lin usuel, i, 2 Lindenber, co rticesfolia, iii, 6. champs, ii, 542. 48 Lisha, iii, $78. Litseea sohifers, iii, 211. St cksii iii. 213. 7 ‘ittle man’s bres iii, 629. Lobelia are itansetolin: ii. 322. ] sobeline, Lobus echinodes, i i. 497. Hi. 873. ; sodhar, ii. 373. Lodhra, ii d odoicea “seychellarum, i iii, 526. i , ili. 296. Lokhandi, i. 294, 355, ii. 35, Lola-sara, iii iii. Lolium um temulentum, iii, 585. London & Hooket, ic-izi, Loran Mi S3T. Loranthus falcatus, iii. 231. ongifl i, ii. 370. Mayet, i. 298, 301. Lubanat, i INDEX. Luywan, iii. 628. Luzanine, i. 485. uzini a Lythracez, 3 37. Ma, i. Ma7ei-Khiiaf, iii, 366. eee i eb Mabli, | Macar aus | Roxburgh iii. 315. Macassar oil,i Mace, i fe (Bembay), iii, 197, ace: i 6. iwa-ya-watu-wawili, iii, 506. a-chettn, i iii. eae. i 5 & E 1 Soros & o 3 a “] B ~ hey : mo & Ei no - OS we rat $ oo @ od : z E ~ =| 4 , : 3 — 4 eT Le ger g ee urika, 3 Madhye os va, cB INDEX, 49 Madhyanha- oops iii. 132. Maklai-gond, i. 541. Sa anaes : : _ | Makoi, i ormwood, ii. 248. ees fee -chilanni, i ee aeda-lakari, iii. 211. ulaka, iii. 311. iii. 5 tak sai, 488. gath-i-Hindi, iii. 211. ie Cardamom, iii, 428. “pe i a ii. 211. ” Kino, Maghas-shuddhi, i. 345. : 5 Nightside, 4 iii, 148. “parichelad, i 4 ‘ Malabari-pan-ki-jar, iii. 437 Agodhuma, iii. 608 Malabari-supari, iii. 383 70. J bari-vacha, iii, 441. bhi, iii. 356 Ma. caries ili. 184. 68. Mala i. 204. Ma gchea capitata, i. 228. a Malague, i. 567. Soa Mala -karunnay, i. 260. ‘ Mala-kuli, i. 590. Mabon, 2 ait, 331. Malai-tamara, iii. 503. Ma gi, i. 206. Malai-vembu, i. 330. i. 56 Malai-veppam, i. 330. Mahauaracha-rasa, iii. 231 Malan-kua, iii. 416 e 540. Malbhok, iii. 444 Malilotus, i. 405. Malkanguni, i. 343 Mallea, ti. 211. ] wea age ii hess Spe pS FE; S fo s : amao, ll. 03. la-k onnai, j. 511. AaB Vale - 5. ana-pasupu, iii. 403. teat i. 4 Seok face Goal Gad Mead Bec Mead Bcd Gc bc bed bac Sead . 451. ara, i. 452, ji. 429. aramu, ii. 428 eacora calllescens, ji. 58] da - preset ii. oe a —-. ii. ame: 50 Mandragore, ii. 581. Manduka-parni, ii. 107 Manduparni, iii Manelli, i. All. Mangal, iii - 586 Man, ngalya, i. 23, lii. 390. Mangalyarha, i » 23. Man INDEX, Mari, iii. 338 ie rmakhuz Marmelos de Bangui, 1. 278. Marori, i 5 bed b bead bead bed Be ‘ sy FEE - ne . S mid watu-wa: iii. 666. ath, 1 . te “ ed d ae” tii. 514. latijer, iii, 125. atti-pal, 293. acpi, ii, 534. il, 355 oy ii. 36 z bunthakdoroontho, +197; auve Sauvage, i. Ss: scan acid, i. 88. €conidine, i 88. > 1, bd ead bed es | Onin, i. 88, econopeis nen i 112. INDEX. Ot 34. tinctorium, ii, 35, iii. 297, Mémecylon comestibie, i. 34. Menph 4 Mente, i. 401. Mentha ee as iil. e4. iii. 103 ” ” : _Piperascens, iii. incana, iil. 108, ae » piperita, i _ 103 oy sativa, ill. 103. >, Sylvestris, iii. 101 enthe sauvage, iii. 101 Menthol, iii. 1 Menthya, i. 401. < Mentula, i. 40 i, 155. Meradu, Merabsing ii. 450. > pce persica, iii, 496. Mesha-sringi, ii. 45 Methyl-o pete: Me on baie ren ‘cid it 284. ve wed ig Mill Millett, iii. 580. Mimosa pudica, i. 538. 52 ; INDEX, Mimumuli, Mollugo hirta, ii. 104. — Hine ii. 362. ” spergula, ii. 103 ndra, ii, 364. stricta, ii. 103. Min dal o or Mindhta ii, 204, Mombin de Malabar, i i, B95: . Migut, iii. 253, Momordica weg amet ii. 78. Mint, i hi. 101, ie chinchinensis, ii, 77. Mirabilis J alapa, ii, 132. e Oyaibalacin: 11-79. Mirach, iii. 166 4 dioica, ii. 74. Mirapa-kaya, ii. 563. umbella ata, ii. 89. Mirch, ii, 563. Monkey- = — aya Ee irchai, ii. 530. Monkey-nut, i. 494 rchi, ii. 563. Monks’ penner: iii. 76 ivi, iii, 166, 212 Monora-mal, i. 506 iringa, iii. 15. Mo irigalu, iii. 166 Mooda-cottan, i. 36 ingha, li. 563 Moonoodoo-moordoo, i. 430 hk-bhendi, i. 209 Moorenkappen, ii. 5 k ah, i. 209 | Mora-ageru, ii, 59, 8 taramashia, iii Morala, i. 394. zamin (dr a tor Cyperus), area ve 42. Moreda, i. 394, Morelle’ Fivieue, 2 Abe agit Matinds ¢ citrifolia, ii. 7566. »» _ tinctoria, ii. 226. Morindin, ii. 228 Morindon, ii. + a Moringa peri a ery go oO d otha, i iii. 652. ae 7 ae E: g Moydi, - i338, Beds, ii 3 Sa = fest . 562. : ee in 145 232. Mrinal = INDEX. ~buraga- chettu, i. 215. Mundulea ade i, 417. Mung, i. 488 “i. 556. 54 Myricacese, iil, 355. Myristi ce acid, iii. 195. 192 Myristica cade his Be ; 2g rica, iii. 197. errs Myrrh, i. 304. », (Arabian), i. 306, # hinese), i. 307. is (Persian), i, 307. Myrsineze, ii. 349 LS barrage 17 Myrte, ae. ii. 32. communis, ii. 32. Naanaa, iii. 103. iii. 593. 2 a * rEeea ee Be » 0 Mp, ig > ~ i w bt a jilakara, i, Po B Need Mead bak Bed J ha > wat. aval + ca Sead’ beak bial : arak- 9 ih. 265. ] a-ood, ili 316. t aral, iii. 511. ed bead aral-cha-jhada, iii, 611 iiss OS = on ee aay Seed arali-mad, iii, 511. mamidi, iii. 211. i, 268. ~ Be J eja, iii. 253. Narayana es iil. 483. arceine, arcissus Tazetta, iii, 498. are i. 83, 88. ] ardostachys J atamansi, ii. 233. ardus J 1-kx per; iii. 51] arkachura, iii, 403 ar. g, 2, 2b & & 6B officin ale, i, 130. aum ~papal SREP | 8 27. » " soap, i, 323, Macele: ~gida, i . 24% * INDEX. 55; i. 155. ero coffee, i. 520. hoemeka, ii. 92. udamu, iii. 272. a-bevina-gida, iii, 46. a-vemu, ii. 511, iti. 46. 00000000 & 1 BE st rE of =. “ ~ Voted ha Nélum certs ming i. 70, ; ciosum, i, 70. aline, — Aconiie, i, 1. berry, i, 64 a pr i. 201, ii, 252, 56 Nhola, ii. 92. Nhynu, ii Ni ree, 96. Nicotian aTabacam, li. 632. Nicotianiny i PRs Nicotine, Nictan nthe A Abr triste, ii. 376. idigdhika . 557. Niguri, iil. 73. Nikos, li. 164. ee ‘clon, ii. 530. Nila, i. 406. ~ ‘Nilacum al, iii. ie N ila-kadalai Nila- penaihizhang, lil, 462. Nila-phala, Nila -pulai, i ili. 1%, Nila- -pushpa, ii. Nila Bo “choi ii. 530. INDEX, 7] Steee e 460. Nirbi shi, i iii, 400, 556. rbrami, rgundi, 7 rkirambu, ii. 49 rjara, i.5 rmali, li. 505. irmulli, iii. 36 nochi, iii. 7 J ongelion, iii. 24 E, oF aa. =} Qo i oO 3 ru-kassuvu, iii. 509 el-neruppu, ii. 37 ru-vavill, iii. 73. rvala, i. 135. rvalam, te pea, iti 556. a, Nisan, iii. ] vst tar = Wihotte, ii 527. Nisinda, iii. 73. 1 = ii 507. vali, ii. 505 ] vara, iii. 603. ] oc chi, iii. Noir de cee i, 358. Notonia grandiflora, i li. 320. ] 2 fase eee d aie ] bora Oak, iii. 360. ‘Occhi, i. 418. longifolius i ye aioe eT 83. INDEX. Belorcm Ceareemerige a 85. | Oleum melissse indicee, iii. 117, % 2G 8 menthee, iii. 104, eee, 3 | mesuz, i, 172. Bef mann, i 393, », Moringe, i. 399. i myristice, iii. 196. Odin Wodier, i ‘s pat 548. ic myzrhe, i. 308, diya -maram er ns poets Oduvan, i iii. 369, le i we 5 o eH SPER SEY eG Sg B: . me a B: o> a . ° 3.8 . o i : 2 Be 5 EP eh 8 5 ~ no bo Ophelie acill, 53 2 _ orrhiz Manga ii, 199, eye ii. 417. Operon eae ii, 414. ere ae, "ee 18. » abkari 7 (aaleration ot) is BL oids, i. 82, 87, 92. - ; nee ; aa 75, 89. 58 INDEX. Opium (classification of), i. 103. Padma, i. 74, <2 »» eating, i. 92, Padma-charini, i. 137. », (Khandesh), i. 89. Padma-kasta, i. 567. » (Malwa), i. 83, 89. Padma-pushkara, iii, 451 » (medicinal), i. 88. Padmini, i. 71. »» (Patna), i. 89. Padri, iii. 20, 22. 77 (Persian), i. 89 Padri-gida, iii. 20, 22. eee | ; 9. Padshah-salab, iii. 491. <3 Ne ogy of), i. 98, Peedebiri, ii. 228. Ophthalmic Barberry, i. 65. Peederia kee ii, 228. Opuntia Dillenii, ii. 99. Peederine, ii = ‘una, ii. 100. Peeonia albiflora, i ii. 308. Orange, i. 2 3, corallina, i. 30. me urgative, iii. 278, $5 em0ds, i..8 Oranger, i. 268. 3, Officinalis, i. 29, Orcanette, ii. 524, Pahada-muala, i. 5: Orchidacee, iii. 384. Pahari, i. 53. . Orchis be. iii, 384. Pahari-kanda (Syn. for L. hyacin- a, iii. 384, ‘ thoides), iii, 478. Origan aquatique , ie 247. Pahar-mul, i. 53. Origan’ hg iii. 108. Paidi-tangedu, i. 520, Sill Venaray, i Pain de porceau, ii. 347. ocarpum se pace: i, 430, Pain de singe, i. 220. Oroxylin, iii. 18. Paina-schulli, iii, 42. Oroxylum hits 16. Painpai, ii, Orris camphor, iii. 453. Paiwand-i-miryam, i. 567. 5; Poot, ; Pair, iii. 345, sativa, iii.601, Pakar, iii. 345. Osari, ii. 245. Pakhanbed, i. 585. Oseille de Guinée, i. 212. Pakhar, iii, 338. Osht, i. 167. Pakkn, iii, 422 Ossifraga lactea, iii. 252. Pakri, iii. 338. Otto of Roses, i 5 Pala, iii. 443. Onfa, i. 218. ala-garuda, ii. 386 plate—sce Upalet. Pala-indigo, ii. 398. Ova, ii. 116. Palak, iii, 14 Ovali, ii, 362. Palak-juhi, iii. 55. Oxalide corniculée, i. 246, Palang, ii, 146. Oxalis meg ay i, 246. Palangmishk, iii. 90. Palan-kizhangu, iii. 399. Peevsemphor, iii, 202. Palas or Palash, i. 454. Oxy-cannabin, 32 Palas-gonda, i. 454. Oxymyrsine, ii. 33. Palas-ki-binj, i. 454, Oxystelma esculentum, ii. 457. alas-ki-gond, i. 454. Palas-paparo, i. 454. Pa +i. 454, Palas-vel, i. 458. Paban, i. 71. Pa » 1, 454. . Pa i, ii Palasha-che-bi, i. 454. Palashamu, i. 454 Pa * Paletuvier blanc, iii. 82. Palita-mandar, i. 451. Palla, ii. 364. leru-mullu, i é Palme, iii. 511. matoria d’inferno, ii. 99. Pal-modekka, ii. 534, : 5 INDEX, Palo, i, 55. Panni, iii. 571 iS de Oulebra, ii. 447. Panwar, i, 518 is é ‘apaya, li. imseng’, ii. 162. Papayic acid, ii. 57, : Papita, ii. 501 . 198. apiya, ii. 52 pittha, i. 282. appadi, ii, 21 23 appali-maram, ii. 52, appara-mulli, ii, 555. » lil, 339, appara-puli, i. 218 apra, i. 69. apri, i. 69, iii. 318. 535. putta-vayroo, ii. 211 (Syn. for variegated ‘ara cress, ii. 28 iii. 50. aragalastine, i. 484. » li. 135, arajatak, ii. 376 7 (Syn. for Acacia leu- , ii, 20. ea), 1. 551. Paramenispermine, i. 52. ! kuda, ii. 391. Paramignya monophylla, i. 268, “peru, ii. 30. Paranga, i. 451. ? ur or sauri, i. 216. arangi, ii. 52. » i, 298 rangi-chakka, . -luban, i. 298, a i-shambirani, i. lii. araoxybenzoic acid, iii. 299. ‘ a pipal, i. 213. arasa-piplo, i. 213. arasika, li. 626. ‘ara -mara, i. 451 pes |b : Paripat, ii. 197. Pain 8it, Parkati, Parkatin, iii, 340. Parkura, ii. 376. 59 60 INDEX, Parmelia ~ouiagprergee ili, 627. atte de poule, i. 269, ger on i, 627. Patti-cheteu i. 225. arna-bij, i. Patwa, i : a-vija, i. eal Paushtie, iil ao ; arnaksh, li. 157 Pava-kai, i : Parpadagam, ii. 197. Pavan pehodiy ii. 78. Parpata, li. 198. Pavana, é 4 Parpataka, ii, 103. Pavatierl: - = : t seed, ii. 3 Pavetta indica, ii, 211 Parsiawashan, iii, 624. Pavitraka, iii. 3 artaka, ii. 37 Pavonia odorata, i, 224 -art-bikhta, i. 15, Pavot ste ux, i. 109. > Ti ére, i. 73 arusha, i. 238 Parruttay-vayr, ii. 211. aruthi, i. 225 Payasa, iii. arvati, i. 6, ii, 40. Paytine, ii. 188 Parwar, ii. 73 Pe-attis, iii. 34 Pas d’Ane, ii. 294. ea-nut, i. 494, Pasapu, iii. 407, Pechak, i. 232. F Pasewha, i. 7. Pedalinez, iii. 26. Pashanbhed, i. 585, Pedalium murex, iii. 33 Pashan a-bheda, i. 580. edalu, ii. 207. spies: £: 33. edanganeree, iii. 70 ashpoli, iii. 552 ed omrn, iii. 70. ; uu be, 132.171. Pedd ga, li. 2 : asselie-keeray, i. 158. Pedda-mann, i, 291, 292 | éride, i, 118 Pedda-ni -pandu, i. 268 4 ifloreze, ii, 52. dda -palle . 34. g naca erra atica, - ii, 135, eddagi, i. 4 : is: 286. soit ioe iii. 338. : ata, i. 53, 20 s pectinata, iii. 14. : ‘ata-sij, ili. 253 eget “ 3 atagon, Peela-bhangra, ii. 267. : Patagonelle y. aleriane, i iii 131. Peelcolli, iii, 55. : : Patala or Patali, iii. 20, 22. Pee-mottenga, iii, 556. 4 ji stata palari, i; 57. Pegant armala, i. 252. 4 Patala-gandhi, ii. 414, Pelani, i 4 atala-garuda, ii. 90, Pelambaci, i 207. a ata Somber i (>) rgonium Radula, Tike 561, “4 atala sagecd{ Caporale Whers)yai -456. | Pelosine, i. 54. 4 ] ‘aaa, 3 i. 690, 2 sletiering i . 48, | nga-chekke, i. 500, Pellitory 277. ranga Katia, 1 500. tee eet), ii, 281. ; atchak, ii Peltate Sundew; i. 591. a ate Penari, i. 228. a xa Penar-valli, ii. 94. 4 La Pendhar or Pendhari, ii, 207 a Pendhru, ii. 207. a Penerru-gadda, ii. 566. Pat ima, iii. 564. Pa en, Pentapetes phoenicea i. 235, Pentatropis sloop in, fi ii, 458. sp Pentgul, i i. 461, ii. 212. Penva, iii. 427. Peony, i. 29. Poplta, He 801!" fa ee ee . 64, . 458. as ‘see grav ‘asuns 126. “Kosh (Syn. for ‘Cadsunna), . free: ear nde li, 59. era 122, . 355. INDEX, | 61 Phatar-suva, ii. 271, Ph attar-phoda, iii. 268. Phenila, i. Phoenix x sylvestris, iii, 520, ari, ii. 527. Anders = Emblica, ii iii. 261. draspatensis, iii. 265. ” 5. ” Phyeala, Physalis Alkekeo ey li. 560. Niruri, retiuls, ie Pci minima, Af sep ii, 62. Physic Nut, i iii. 274. Pia-amo u-leck, Me 34. a e, li. 641. Picrasma nepaleiaas! . 291. quass: mane Ph i. 287. Picroth iza a ae ii. 10. Picrorhizetin, 12. Picrorhizin, iii Picrotin, i. 52. Picrotoxin, i i. 50, | oe Pignons d’Inde, iii. 276. erg pd ha he P; reticulatus), Pila’ (Tam. for A. integrifolia), iii. Pinang, iii. 423, 425. a 07 iii, 507, * 6g: . Pinde, ii. 204, 211. de-valli, ii, 95, INDEX. ae Foret volte inthus, i. 377. 5 oe , 1-378, 0. Pistia —— iii. 550. Pisum Sati i. 489, Pita, iii, 408. te ecg de : Pokies iii. 232. pullum Pithooobobinws ‘aio i, 553. Saman, i. 553. Pithvan, i i. 426. Pitkari, ii. 437. Pittosporum pibiadeli’ i. 153. undulatum, i. 154. Shrpenone i, Pv Pivala Piyaa‘icdahi iii. 476. maou 6a Plantaginess, i iii, Plantago emplexicalis, iii, 127. a tan packet oar 5 ie ce Bs 3 ; ; ‘Y i. Po’de Bahia, i, Ee Podophyllin, i. py tom cna, i. 69, Podu talai 0-yo, ili Doct, Sy iii, 95. purpuricaulis, iii. 95. Pogostemonine, lii, 101, Poi, iii. 148. Poinciana elata, i i. 507. »» pulcherrima, i, 506. i. 549, » regia, i Pois d de marveille, i. 366. Poison nut, ii. 458. Poivre Tong, So 2 Poi min: de Baie, eA 183. Pokala, i Po Seatlrairt ‘i. 175. Poka-vakka, iii, 422. Polenta, iii. 580. Poley-Germander, iii. 94. Polianthes tuberosa, iii. 493. Polycarpeea corymbosa, i, 153. Polychroit, iii. 458. olygala is, i P oineee, i. ‘ee ioide: 155, ” tlephicdes, i. ‘8s. » tenui ct val — i. Bg Polygalesa, i, 154. Polygonacee:, iii. 148. Polygonic acid, iii. 150. Polygonum alatum, iii. 150 aviculare, iii. 148, 158 a5 barbatum, iii. 15) o> Bisto oy iil. 150. » glabrum, ili. 150, 152 ” Hydropiper, iii. 150 ne ee ie vivin " 150 50. Ppion querciflinm, iii, 623, _— jum, iii. 624. bara , lil. 621. a, oficinalis iii, 631. Pomegranate INDEX. - et tet 2 i. 368. Pondacarapan (Tam. for Celtis), Popli-chukai, i. 355. pee hea er 87. 6. Post Posti-pisteh, fe 380. Postaka- tol, i : 3. 63 64 INDEX. p., i. 567. Punica protopunica, ii. 45. Pseudo-aconine, i, 6. Punico-tannic acid, ii. 48. Pseudo-aconitine, i. 5. Punjabi, iii. 387. Pseudo-chiratin, iii. 267. Pun g. i i Pseudo-curarine, ii. 401. Punnaga, i. 17 indican, ii. 409, Punyatrina, iii. 575 seudo-mo: ne, i. 88, Pupal, Psidium Guyava, ii. 30. Puppanti, iii. 291. Psoralia cuxynte olia, i, 412. Purasha-maram, i. 21 Ptérocarpe'4 bourse, i, 464. Purashara-tanam, i. 139 Pearioarsitie, | Purashu, i. 454. Pterocarpus Draco, iii Purging cassia, i. 511. ; ium, i, 464 Purna, iii. 130. santalinus, i. 462. Purple Gueveee'L i. 120. Pencarian acerifolinm, i. 233. oat’s- . 415. erifolium, i, 233. i >urslane, ils 3. Ptye hotis ts Awan, it. 117. Purvali, iii. 5 Pode ii i, 488. Pushkara- mula, ii. 296, iii. 451. -udhira 365. -ushpa-kadal, iil. 55. Pudins, “tii. “101. Putai-tanni-maram, ii. 19. Pudina -ke phu ul, i, 424, Puten-budinga, Pueraria tuberosa, i, 424, Puttay-charagam, i. 556 i 2. -utikaranja, i. 4 Putiki, i. 238 -utol, iii. 287. -da, ii 1 utra-jiva, iil. gee : -jiva, iii. 271. -utranjiva Haideabhis iii. 271. erent, i. 370. Pyrethrine, ii. 280. Pyrethrum umbelliferum, ii. suns Pyridine, ii. 641. Pyroxylin, i. 226. d communis, ¥. 581. 3, Cydonia, i. 579. Qu matron gt 120. Quinovin, ii. 188, 375. Quisqualis i indica, ii. 13, Sarno i. 492, Racine de 8 Christophe a 36. xy Mungo, ii. 200. %”y Mustela, = 4] » pa Christi, iil. 385. »» puloronica, iii. 1 toxicaria, ili. 4 vesicatoria (Plambago rosea), se = 9. 42. Ragat-chandan, i, 462. os, i, 338) $52. wag : Madre de D th ‘Rai sagt eos, ili, 7 , tiie 72. ~ oH. jana, ti. 21, ier iti. 408. jouibesn it 493, Rajanihasa u, ili, 551. ; : rh i. oe » St oe) Raswanti, i. 65. --- + of INDEX. eee iii, 85. Ren-parval rs 93. wa (Ackodadoad hirsuta), Rakenoateces 8, 1s: 1< ————. bs eee (Se 2 zi eratus, i. 37. ae Bapbaniatees: i. 490. «129, tata 4 Pa THe an, ii. 209. * Rasin, 1. 4 Rasna, ce 200, 260, iii. 392. chaka, iii + 393. Weanwylly i 65. > Se ee atamba, i. 164, J nd, ii 153. : aw wand-l- > 3 ae e Bas mo: fr} ~ > d-sem ca 6 or affiower, ii. 308. ii. 453. 5) batard, ii. 308. Safsaf (Arabic for | Salix capren), 3 doen ii tot 245. sie $82. iti. 390. jyamam, i. 47. © 68 : Bakar-cl-ushar, j Sakhis (A. lanier iii, 563, _-coorgdeea Sakoh, Species, lii. 365. Aa E BE alive, i. 216. a “ile de YInde, ii. 446, ie ie AAT, hoes ok ee PeerERES. 5 . 54 ee vistas, iii. 421. _ Sambara-valili, 3. 363. Sambhalu, no 73, 76, Samt iii. 564 INDEX, ; samrat-el- asl, 12 ‘ 62, : emrat el- oe i. 160. Samudar-phal, ii. 17. ar- ’ ii maudra pacheha, i ii, 541. 03058 Beer ala, . O41, amudra-pu tenkay a, iii. 520. amudra shokh, i i. 54]. araudra sic ii, 541, amudra-yogam, ii. 541. sok, ii, 89. ; eucane =pallatn, i lt ne Bree il, 68. 400. andal, iii pete Ange iii. i. 232. > ican, iii, . 247. ae i. 542, Saeed antal, i 3 = cefoliets, i. 367, ' Sa apista 374, di apd ii. 365. Sepowenin 157, 369. fe) untry), As 446, iii. 500. aeons ny) 57, 4 gand Satar, iii. ti Bajar apes eat ‘for T. serpyllum), INDEX. d phal, ii. 17. atudo, ii, 102, ureia greeca, lil. 116. aturi see Satyri ataryus, saat ( (ene for “Anise), i iG 13k aur, 1. 215, , Sa i iii, — J o 3 gs sae o * 3 weinturthia sp. ch rocarpa, iii, 7 10 as iii, 476. fiicinalis, iii, ebesten plum, ii. 518, sage emetica, ii. 458. ee Bi. elu, ii em or semis-gond, i. 587. einés emencine. i tan. 69 70 Séné, i. 526 . 528, Renaliive sense, 1.0366 plan oo Seoti —see She = sickaeapag A ii, 316, Vi. 73, Sesame, iii. Sésame de VInde, i ue ae oe indicum Sesb nia Mgyption, i. “tA. », grandifi i, 472. Sevaka, i, 7 Sevya, ili. 339, 562. Sewar, ii. 3 Shadanga-paniya i; 224, Shaddaranayoga, ii, 3 329 airatepl-eharachi i= D i. 582 ha rat-el-kapur, ii. 275. INDEX, Lope CELTS ~ riggers Shankhini, ii. h saa i, 462, ar nradi, 592. ran- “kota, i, 389, 123, pibbit, ii. 128. nibjal, i. 366. INDEX, 71 Shud, ii. 128. m, i. 5 ebetiité- ral peas ii. 274, Shulkzi, i. 238. : Ehime -dalima-vittulu, i. 579, Shulundu-kora, ii. 215 Shima-jeventi-pushpam, ii, 274 Shumach (Sumach), i. 372 9. humshur, ti-vittulu, i, 252. ~ Shuniz, i. uprak, i. 33, Shurali, i. ne hurava, i. i. 252, Shushma, Shashmir (Cardamoms), i tis. 1. 274. 428, : Shuthi (Zedoary), iii. 399. cts! i. 579. Shwet-basanta, iii. ii ‘ Shyavantige-huvu, i ii, 277, ahi Roca e Siyah. Shim. mba, 579, Sia lini 404) Shime-jicige ii. Siam Benzoin, ii. 371. ( shyamantigo, ii. 274. Sida carpinifolia, i. 206. », cordifolia, i. 206, ” _ mere » i. 208. 9 rhombifoli i. 206, idha Siddhi (Syn. for Cannabis sativa), ili. ieges' esbecki an Onlentele ii. 264. Sigepruppuss, i i. 37, Shima. Sima- pwr 1 aa Bik ii. 274, Sima-jilakara, ii cimarelban, a. ho, 72 Sind Opium, i. 89. Sin dhuvara, iii. 73. k ira-punnai, i. 175. Sira-she neal, li. 243. reg tae , 561 Sire 565. Ds Sits or Sivas. i i. 561. 2 a “s oo Sirra-kanchort-vayr, iii. 313. Sirru-se ali j ii, EL Sis, 3. 401. Sisaliyus, iii. 124, Sisiban, i. Riera beac Alliaria, iii, 490. 9 Hopi. 127, a officinale, i, 122. . 540 INDEX, Sohanpe- isp di it rarer ae ridin 658. Solaaine j Solanum Duleamea li, 549. li, 560. 3 in vies e Jacquinii, ii. 557, es nigrum, ii ‘a torvum, ii. 5 me rilobatum, er lis ii, 560, anor ii, 507. Somua-va sik , iii. Solidago odora, ii. eek ire: lassen hia 2475 S manti, i 4 Somballi (ina, for Chrozophora plicata), iii. 316 Hy onchus sleracen, ii, 315. ondhali, one-patta, iii. es lii. sae. ongarvi, i. 450. onsali, li, 251. ae Sonti, i iii. 420. oo— opu, sg —) = 14. jorghum vulgare - Sothagni, iii. 1¢ youci des jar “ li. 322 ou-line, i. § owa, ii ow-bread, ii. ‘ Soymida febrifuga, i. 336 P asmine, ii. 378. ; ellitory, ii. 277. - 207. eeroc compressus, iii. 635. - Spitatithes Ac Acmella, ii. ee C . ondhi (ind, for A. laniger), iti. 563. pogel seeds, iii. 126. ‘Spondias seats z 395, 549. nS, rmum chelonoides; iil. 22, veolens, ili. 20. um, gt 3. resin, i. 598, Se ogra iii. 40. r=] = Ce te Wey ukhada, 2 ukhe aan iii. i 64, 466. ukkapat, li ukkar, iii "395 =P pika, ii sultan-champa, i. ultan-el-ashjar, i. 562. umak, i. 372. umatra “Benzoin, ii. bd di, ii. umpura, i ng, ii. 384 Aare x i. 215, ii. 424. cee pil, ine, ii jurdan, ie 122. suringi, i. 172. 73 74 INDEX, urinjan, iii. 495, Tabernemontana “rman ii. 413, urinjan-i-shirin, ii. 497, 3 Heyneana, ii, 413. arinjan-i-talk, iii. 496, “ utilis, ii. 413, uriya (Hind. for, ae neers iii. 563, | Tabsnu, i. 228. urjavart 132 f acamahaca, i i, 174, urpa, ii 35. Tacca aspera, iii. 54 urpan, ii. 285, Taconnet, ii- 2 urson, i, 123 Tadki-erandi, iii, 272. urugen, = 496, Taftaf, i, 367. urughundu-pu atta, i Ta-fung-tsze, i. 146 uryay reign for 6, “plicata), iit 316, | Tag, i. 400. jus, i. 492, iii, 379, : agar, ii. 238, usan. iii. 469. Tagar-ga etic ii, 238. ke ieenan josh iii, 452. agara, ii, 2 man, iii. 29, agara-chettu, i, 520, ushava, ii. 119, agaral, i, 515. ushavi, ii. 79, Tagarisha-chettu, i. 515. at : agetes erecta, ll. 32 tranabhi, ii. 414, aggar wood, uva, li, 128, Taggi, iii. 6 uvali-amli, i. 539 aghak, i, 3 uvaranaka, i. 511, a-hai-tsza, i. 230, i valpa-jiarankusa, ii. 585. a-huang, iii ee ete i, 402. Taindn, ii. 362, 366 vayambhu, i. 4 aivela, i vet-barela, i. a aj, lii. 204, 208 gothubi, iii. 556. Tajpat, iii. 209 veta-maricha, i. 396. ak; i. veta-murga, iii. 139.. akala, a-punarnava, ii. 102, akdokhyen, i. 530. veta-purna, iii. 131. akhak, i. 3 veta-salmali, i, 216, akkarike, i. 515 waheli-pippali, iii. 179. akkile, iii. 66 sweet Basil, iti. 83. akmaki, ii. 65 Chiretta, ii. 514, akub, iii. 258 ” g; i. 538. ~ aa oat 9» Pellitory, ii. 281. », . Tangle, iii. 641. nln (an for Musa paradisiaca), Swertia angustifolia, ii, ” hirata, ii. 511, iii. 540. Ta saakincionre 3 iii. 159, » corymbosa, ii. 515, Talavaranaballi, ii. 44,2. ‘. decussata, ii. 515. Tale, iii. 535, » pulchella, ii. 515. Tali a, iii Swietenia mahogoni, i. 648. eietgeerme os _ = 9 Soymi , 3 alisfar, ii. 393, Switch Sorrel, i, 371 cert renee iii. 208 "S16. os, iii. 602, Taliskatar, yama, ii, 424 Talk, iii 443, Syamalata, ag er os almakhana, iii. 36 , oer osa, almakhara, iii. 36, Sronaka, i i iii, 547 Talpalang, iii. 15, Tamaku, ii. 632, n es /Lam ) °% 168, e ssl Tea as ii. 27, | Tamala, i. 169. : Tabac, ii, 632, sree Begiege iii. 588. Bene : Tamalpatra, iii, 209, ip Be 148, INDEX, | 5 wap? erage i, 532. E arwar, i. 519, ‘ashmizaj, i, 524. i. 532. Bi amarinier de 1’ Inde, i. 532. atrak, i. 372, 374 Tamarisc de France, i. 159. , ii, 586. 2, i ‘avadarum, i. 242. Tavakhir, iii. 406. i; avakshiri, i Tamarix articulata, i. 161. 'averniera nummularia, i. 447 ca, i ‘axine, iii, 377. 632 ‘axus baccata, iii. 373 Tamra. ‘aye, iii. 471. bara-chandan, i. 462. azha, ili. 535, li. 63 ‘ea, i. 176. ru, li, 30. eak, iii. 61. i, i, 286. ectona grandis, iii. 61. hi, iii, 563. ee—sce Ti. egada, ii. 527 , 1, 256, iii. 185. egada-veru, ii. 527, ii. 1 egarasi, i. 515, amra—see ay ecu, ili. 61. i ejbul, iii. 315. -valli, ii. 231, Oi. 266. ejpat, iii. 209. a i, i: 345. . ejphal, i. 256 1 57. ejraj, li, 203. umbelliferum, li, 281. ekari, ii. 561 | Tekata-sij, iii. 253. odhar-thohar, iii. 254. kku-maram, 61. ii. 6. Teku-mant, iii. 61. elakucha, iii. 86. , iii. 511, cinale, ii, 315, Tentul, i. 532 Tarbuj, ii. 63 : . 527. Tephrosia ss ii a 5. ? * * il a ” _ guberosa, i. 417. E & villosa, i. 416. virginiana, i. 416. Teramnus labialis, 2" aie Terminalia Arjuna, ii 76 : INDEX. — belerica, i. 554, ii. 5, Catappa, ii. 16. 7s Chebula, ii. I $5 citrina, ii e glabra, ii. 16 ‘5 aniculata, ii. 16. sale a ii. 16, Terns ‘troemiac i. 176 Tetran-kotta, ii. 55 ran-parala, Tetranthora laarifolia, iii. P11. Tetu, iii, Teucrium Chamedrys, ii. i. 257, ili. 225. 9 lium, iii. - Scordiun, iii ab, » , Serratum, iii Tepak, iii Els Thada, i. 237. Thalikrum cm Lod. areas 2, i. 148. vel, ii . 230. eophylline, Thespesia a fuillee ti nes i, 213. populnea, i. 213 he | Thymus perc ay iii. 109, vulgaris, iii. I11. Tiaidiom—se 3 Heliotropium. Tibiliti, : di, Tigadike-puti- pak ii, 527. Tige-m peta a, i. Tigdu-mara, iii ts Tiglinic acid. iii, 284. | Tikhur, iii 406 Tikri, i. 53. Tikta-badami, i. 563 Tikta-lau, ii. i e, 357. Tinospora cordifolia, i, 54. crispa, i. 64. Tinpani, i i. 333. Tinti, ii. 527. | Tintidi, i. ge Ti ppa-tige, Tippali or tipo oo — Tippali-mulam Tippali-ver, iii. er i INDEX. : 77 Tribulus alatus, i i. 245, Tischdeuice Africanum, j ii. 523. iy oo ii. 622, eylani um, ii. 523, Tricholepis Sate errima, ii. 308. Trich SOE cucumerina, ii. 72, dioi 7 ca, ii. 2. 5 laciniosa, ii. 74. ‘9 peccate, | li. 97, ata, ii, 70 Trichosanthin, ii babs Tridhari- nevalmagay ili. 253. ae Trifolio, i Trigonele corona, i, 405. Fonum-grecum, i. 401, 404, s ikatu, ili. im mine Tri iepancha-tila, i iii. 693, uta, ii, 527 puli, i. 489. ticum sativum, iii. 607. Triumfetta, i, 238 vacate, i, 238, Trivrit, li. 627, Tropwolum majus, i, 121. Tropine, 577. Truti, iii. 428. Tsiet tti-mandara, i i. 506. Tsjakala, iii. Tsjerou-kanelli, ii Tsjerou-katou agen 267, Naa . 414, - uberose, a Lehmanni, ii. 136. Tubocuty, i Prackylobinntfornemannianum, 1.510. te flah--ard *t 275. Tuk-kung, i eS 2 Ta njudan, ii. 126. Tukm bala g, iii. 9 Tu balasan, i. 316 -i-gul, i. 575 ie vines Eafzhah, ii 308, Tu kahu, ii. 314. Tul kajrah, ii. 308 Tra kasus, ii 54 Pakw-ickasirsb. ti, $08: C.D 78 INDEX, ‘ukm -i-khitmi, i, 201 Udalai, iii. 272. ukm-i-nil, ii. 530. Uda asaligun, i ii. 122. ukm-i-rihan, iii. 8 Ud, iii u i-sarwali, ili, 139. aspen iii. 356. ‘ula, ii, 566 Ud-el-jibbali, ii. 278 ulasi or Tulashi, iii. 86 Ud-el-juj, iii. 219. ulati-pati, ii. 561. Ud-el-k ge ii sates ulipa Japonica, iii, 466 Ud-el-sali 1, iii. 86. Ud-el- -waj arab, ‘for A. calamus), iii. umatti, ii, 59, umba, ii. 67, iii. 123, Ud-i-balasan, i . 316. umba-phul, iii. 123 Ud-i-gharki, iii, 220. ‘umbi, ii. 67. Ud-i-kham, 220 umbilik-kai, ii, 366 Udifarunas, iii. 323 i, iii. 123, Ud-salap, i. 30 umiki, ii. 366, Uduga-chettu, ii. 164, umra, i. 256 U , iii. ‘umri, iii. 294 Ughai-pattai, ii 330. un, i, 339. Ugragandha, iii. 488, 539. dika, ii. 86. Ujli-musali, iii. 485. eri, ii. 86. Ukh, iii. = unga, iii. 513. Ukshi, ii 4 ie B00. ee kant, i, 233. unja-muste, i, 552 ‘unna, i. 339. Ullax-billar, ‘upkaria, i. 206, Ulmus—see ” Holoptoles nei. Umbar (Syn. for F. ee eee ee ee eee ee ee ee glomerata), a; ii. 1j, 112. Uniehte seatentae | i, 34. Uncaria Gambier, ii, 172. orgs he iii 272. Undi Undirche. tel, 2.173; Undirkani, ii. 539, Unga, iii 135 Unhali Uraria picta, i, 437. Urena ek i, 228. ay ak, il, 156. Ushana-chatu- ener; iii, 169. arama 178. Ussarah- Bihre i. 168, Ustarkhar, i Ustukhudu Uvas ~ AE i, 362. zmet (Syn. for “sylvatica, iii, 547, , iii. 426, sting he Sis. Synantherias INDEX, rene eee sie Yake-ponbe, iii. 14, Vaka-vri 12, BEES aa A A aA A a Seeitrits PPeife 9 2 Aare we | 23 ag ans i, "687. 9 80° | INDEX, Vana-sunthi, ‘iil. 420. Va i yavarna "eerie ka, i. 54, -. aykkavalai, i. 416. Vanardraka, iii. 426 ler eee = ange ve u- gam, li. 349 Vanda, iii 393. see een le a ‘ a iii. 392, Vedakodi, iii. 48. wees spathulata, ili. 396. \ Vandellia erecta, ili f i i. A en “hala, ii, 300. pedu neulata is 14. 1 ae hd anga- adeuthay, ii iii. ie” ak hen i. 18 ia spinosa, ii. 211 A ae hae Vaahiruchi: i. é = a = 412. Van 1. 48 ekhali, i. 153 Vansa, iii i + 60 Ve ee ay oe Vansa- lochana, iii, 586, = aia - ae Vapala, ii. 81. Ve hater tas iy Vapala-bij, ii 82. Veto 3 ata, iii. 33 Asti Vara, iii. 339, 454 ve ae t 42 Vv z : Serine deh anes bg a e See li. 442 Vardh me slag Var oi 3 a-ellay, 1. 202. Maer a-kadamba, ii. 169 Varnavat, iii, 408, ink gnceaiae mh Varsangi, ii, 211. eB Beh be ome Pi tate —— ti. 555. oe ae Baws 1 ‘situa e da-marani, #211; Varese Liss. Venlo ae Varunadya pe ce ” - pos ae Bhs See i sei Varvara, iii. : : = = Yass, if, 659, Valle, fon erage 4 i “ Ve rsdn na Vasaka, Vembadun =e adam, i. 355. agen sksheps, i. egtos 418, Vembu, i. 3 3 Vv meres re sae tne hag Vasan-pullu, iii. 564, creme ee Vasana-valli, i, 57 Armee dames en Vasanvel, i. 87. Vent ii. i-maram, i. 464, Vasare, iii. 2 e ahes a, Hi. ‘$56 se malaka, i iil; 6716 Veshansvi, i. 1. ot ,i. + BOs Vashira, iii, 543, eee aie, ie 50 Vasicine, iii. 53. a sitiiiaics, | is 355. Vasira, iii oye ae eo tl Mats hon, eppa-chettu, i, 323 Vataton (8 oe for. -bengalensis), i iii. 338, Ms ; - 3 ates ai. eratroylaconine, i. 5 Va 7 i 01 : Verbascum Blattaria, iii. 2. atsanabha, i. it. " ig, Ail, 2 Vatta- killa a kill Verbena officinalis, ili, 58. ry Rte i. 400. : cone, iii. 57, Vattekoka, i. 500. eee dor, ii. 247. Vattu A & tte de Canada, ii. 249, Vv, -vemu, il. 197. : eritel-nep, ii. 262, ; Verjuice, i, 358, Verkati, ise Verk- kadali, Vernonia an ilminticg i. 241. 1, 243. INDEX, Violette odorante, 1. 140. ss i. 130. iolin, i. 141. Vigra, ii iii, 339. Mh sede -srava, iii, 468. iii. 422. Vival-elll, i Voandzeia aa i, 495. Vola, i. Weluarella divaricata,. ii. 306. esta ameter ii. 458. Votam 81 ba (Syn. for A, Lakoocha), iii, Jrihat-pancha mula, i. 244. i. 400. nushni YL dddicdicic = “% BRP ES Fe aes op Se o9 Rs 7amma, 338. r one aon iii. 146. Wagata, i hat shanti oe "Waaheti, j i. 136. a. (si ys for Acorus Calamus), iii. fais r—sce — khm: A at aA al ih Ah surasi, i. : alu-chi the i, ii. 105 andar-bashing, iii. 623. andar-roti, ii. 320. ar (S or F, bengalensis), iii. 338. asm: oe oe ee ae ee ee oe ee ee 2 ay? ~ toe . oo a) chameli, i; 12, 19; 65. Withania a coogulins, i. 569. fera, ii. 566. ak, ii. 157. Xanthium Strumarium, ii. 262. Xanthopicrit, i, 67. Xanthos ostrumarin, ii. 263. i. 31 ? Xyri 8 indica, iii, 510, Yajniya, iii. 339. Yakke-gida, ii sf BE “a EE i # INDEX, 83 ‘Yavana- -parpata, ii. 198. Yavani or Ya anika, ii, 116. cy: . 418. - 509. erba = Pwo iti, 266. -Yercum, ii. 428, 23. : eather, iii, Ss Zan thoxylin, i, 259. “idee my Nl i. 255. — atum ” arty i. Bos ” Hamiltonianum, i. 256. > oxyphyllum, i . t. 256. % ” ritum, i. 256. ” etsa, i. 255. anzibar as eg iii. 506. apan iflor. , li. 375. aru or Zarv, i i. 595, ii. 370. arumbad, iii. 399. shalt ii. 70 atar, ataria uliorg lii, 114. 579. ea Mays Dioaive june, lil. 397. edoar, i. ee edoarin, i'd edo: iii . 399 chneria sumbellata, li, 89. sa t fa (Ghacadl), As eee hire, ii. 114. 116. y Saasber Cassa, iii. 425. Nia Zir- "21-alcillehs ii. Zizipho-tannic acid, i se i pain eg a 381. Fug ose, Zylose, ii 29 APPENDIX. RANUNCULACEZ, On the Crystalline Alkaloid of Aconitum WNapelilus.* ssrs. Wyndham R, Dunstan and W.H, Ince, Ph.D., have Siventigatea the properties of a crystalline alkaloid obtained from the root of Aconitum Napellus by extraction with amyl alcohol, as ong gested by the late Mr. John Williams (Pharm. Journ. [3], x 238). For a supply of the material they are indebted to the ara of Messrs. Howards & Sons, of Stratford. The yellowish indistinct crystals melted at 183°4° (corr.), and by erystallization from alcoholic solution were proved to be associated - with a small quantity of a gummy amorphous base. On combus- tion the original substance gave numbers. agreeing fairly well with the formula C**H**NO", which is that proposed for aconitine by Wright and Luff (Journ, Chem. Soc., 1879). The alkaloid was puri- fied by repeated crystallization Sect a mixture of aleohol and ether, or more readily by conversion into its hydrobromide and regenera- tion of the alkaloid from this salt or by regeneration from its crys- talline aurochloride, It crystallizes in tabular prisms belongiag to the rhombic system; the crystallography of the gente has formed the subject of a separate inquiry by Mr. The crystals are very slightly soluble in water and light Oaeie more soluble in ether and alcohol, most soluble in hansen and chloro- form. They melt at 188°5° (corr.). Contrary to the statements of previous observers, who found aconitine to be levo-rotatory, the authors found an alcoholic solution to be dewtro-rotatory [alp+ 10°78°; the aqueous solution of the hydrobromide is, however, levo-rotatory [alp—30°47°. On analysis, the pure alkaloid afforded results which agreed best with the formula C**H**NO™, Two crystalline aurochlorides were obtained. One (C°**H*°NO™ HAuCI*), melts at 135°5° (corr.) ; the other, a basic aurochloride (C**H**NO'*AuCl), melts at 129° (corr.). These compounds are obtained without difficulty, and afford trustworthy means of * The substance of a communication made to the Chemical Society, March 19, 1891. 86 APPENDIX, identitying aconitine. The alkaloid may be readily recovered from them in a pure state. Aconitine is not appreciably affected by heating at a temperature below its melting point, but at this temperature it is gradually con— verted into the uncrystallizable base aconine. Prolonged boiling in aqueous solution induces a similar change, but not to the same extent, unless an alkali is present. Boiling with water acidulated with hydrochloric acid also produces decomposition of the alkaloid. Dehydraconitine or apoaconitine is a base differing from aconitine by the absence of a molecular proportion of water, which was first obtained by Wright and Luff by acting on aconitine with acids. Its existence has, however, been questioned by later workers, The authors find that such a substance may be readily procured by heating aconitine with saturated aqueous tartaric acid in closed. tubes, as recommended by Wright and Luff, The erystals of this substance melt at 186°5° (corr.). It forms crystalline salts, and in other respects closely resembles the parent alkaloid. The results of analyses agree well with the formula C**H**NO™. Three auro- chlorides were obtained. One (C*H"“N OM HAuCl*) melts at 141° (corr.), This salt, when crystallized from aqueous alcohol, becomes a hydrate— (C*H**NO™“H AuClH?0), melting at 129° (corr.), isomeric with aconitine aurochloride, into which, indeed, it very readily changes. The third aurochloride is a direct compound of the alkaloid with auric chloride (On no AuCl?) ; it melts at 147-5° (corr.). An amorphous base was obtained from aconitine, together with benzoic acid, by prolonged heating with water in a closed tube. It _ appears to be identical with the aconine of Wright and Luff. The same substance is formed together with a resinous substance when aconitine is heated with an alkali, Neither aconine nor its salts could be crystallized. The amorphous base, after purification, and its amorphous aurochloride, afforded analytical data agreeing respectively with the formule ©?*H**NO™ and C?**H#“NOUMHAnCI. The Alkaloids of True Aconitum Napellus. _ Professor Dunstan and Mr, John C. Umney have examined the alkaloids of true Aconitum Napellus plants grown by Mr, E. M. _ Holmes, at the instance of the British Pharmaceutical Qonference, APPENDIX. 87 _ The alkaloids were extracted from the root by the following process, __ which precludes the possibility of the occurrence of hydrolysis, &c, :— _ The solution obtained by percolating with cold rectified fusel oil _ (b. p. 100 —182°) was agitated with water acidified with 1 per cent. of _ sulphuric acid, and the resin having been remoyed by extracting the acid solution so obtained with chloroform, the liquid was made just 4 a alkaline with dilute ammonia and extracted with ether, which dis- solved out a considerable quantity of alkaloid, but Jeft in solution a _ further and smaller quantity, which was subsequently extracted ty agitation with chloroform. The alkaloid soluble in ether was ained as a gum-like mass incapable of crystallization. By con- Version into bromhydride it was separated into a erystallizable and an uncrystallizable salt. ‘The crystalline product was identified as the salt of aconitine, the separated from the pure bromhydride melted at 188-5° (corr.), and forded en combustion numbers agreeing with the formula O**H** “. The specific rotation of the bromhydride in aqueous solution ascertained to be [a])—29°65, a value which agrees with that pre reviously recorded. As some doubt exists as to the solubility of aconitine in water, a determination was carefully made with this pure ‘Specimen, The mean of two determinations gave 1 gram in 4,431 ‘grams of water as the solubility at 22°; Jiirgens had ee Tecorded the far greater solubility of 1 in 745 at the same temperatur ‘The non-crystalline bromhydride furnished a gummy alkaloid oluble in ether and alcohol, but only sparingly soluble in water, the aqueous solution being alkaline to litmus, and very bitter, but ‘Rot giving rise to the tingling sensation so characteristic of aconitine, Not only the alkaloid, but also the chlorhydride, sulphate, nitrate and aurichloride prepared from it could not be crystallized. This alkaloid not identical either with aconine or with the picraconitine of Wright and Luff, A full account of it will be given in a later paper, con- siderable progress having already been made in the most difficult task of isolating it in’a pure state. The authors propose to assign to it the name napelline, which was first given to the alkaloid now known pseud: 88 APPENDIX. is probably associated with another amorphous alkaloid about which they have at present little information to give beyond the fact that neither it nor its salts appear to crystallize. The alkaloid soluble in chloroform was proved to be aconine, the compound which is obtained together with benzoic acid on hydro- lysing aconitine. The roots of true Aconitum Napellus, therefore, must be held to contain three alkaloids, one of which is crystalline, viz., aconitine, two being amorphous, viz., napelline and aconine. Indications have been obtained of the presence of a fourth alkaloid, which is amor- phous and closely resembles napelline. The authors find that the juice expressed from the roots contains a large proportion of amorphous bases but very little aconitine, the greater part of this latter remaining in the root, from which it may be extracted, together with the remainder of the amorphous alkaloids, by exhausting with amyl alcohol. The total quantity of amorphous alkaloid obtained amounted to more than twice that of aconitine. The physiological action of the alkaloids referred to is being investigated. The results so far obtained point to the conclusion that crystalline aconitine is by far the most toxic of the alkaloids contained in Aconitum Napellus. The formation and properties of Aconine and its conversion into Aconitine. Owing to the uncertainty which exists with reference to the pro- duct of the hydrolysis of aconitine, Professor W. R. Dunstan and Dr. F, W, Passmore have re-investigated the subject, using a pure alkaloid. Wright and Luff have stated that when aconitine is hydro- lysed, the sole products are aconine and benzoic acid. More recently, however, Dragendorff and J urgens have asserted that the hydro- lysis occurs in two stages, their contention being that benzoic acid and an alkaloid identical with the picraconitine isolated by Wright and Luff from the roots of Supposed Aconitum Napellus are formed in the first stage, while in the second stage the picraconitine is hydrolysed into benzoic acid, methyl alcohol, and aconine, which last is the final product of hydrolysis, The authors have carefully hydrolysed pure aconitine by heating it with water in closed tubes at 150°, but have been unable to obtain at ge either picraconitine or methyl alcohol, The alkaloid APPENDIX. 89 tracted from the solution by ether was proved to be a mixture of onine with unaltered aconitine, Using pure aconitine, action ecurs precisely in accordance with the equation O° H**NO™ + Us *H* NO" +07H'O?, leaving little doubt that aconitine is benzoyl- — onine, tide, bromhydride, sulphate, and nitrate. All these salts are soluble in water, the chlorhydride being least soluble and the est to crystallise: it is best prepared by crystallisation from a ture of alcohol and ether; when dried at 100° it melts at Jo=—7'71°. It combines th auric chloride, forming an aurichloride considerably more soluble Soluble in water ; the aqueous solution is alkaline. When dry it is insoluble in ether and almost insoluble in chloroform. It isa power- ful reducing agent, precipitating the metals from solutions of Id and silver salts; it also reduces Fehling’s so tion. 7 iological action of pure aconine is being investigated, ite us solution is slightly bitter and gives rise to 8 burning ion in the mouth, but does not produce the tingling which is ee : 90 APPENDIX. characteristic of aconitine. In respect of its action on polarised light, aconine exhibits the same peculiarity as aconitine. Its salts are levo-rotatory, whilst a solution of the alkaloid is dextro-rotatory, [a]y>+29°. When heated with alkalis, aconine slowly resinifies. The action of various re-agents on aconine has so far not led to any important results. Nitrous acid fails to attack it. The principal product of its oxidation by alkaline permanganate is oxalic acid, Attempts to isolate an additive compound with methyl iodide have been unsuccessful. By the action of methyl iodide on aconitine a crystalline aconitine methiodide (C**H**NO-CH®I) was obtained, which melts at 219° (corr.). The aconitine methhydroxide octane from the compound (ChEENO™. CH°OH) isamorphous, and the salts which it yields do not appear to crystallise. A further study will be made of this com- pound, and its physiological action will be investigated. Professor Dunstan, in conjunction with Messrs. Harrison and Carr, has continued his investigation of the aconite alkaloids, and the results were communicated to the Chemical Society, February 2, 1893. It was discovered that aconite root contains an amorphous alkaloid, napelline, which is isomeric with aconitine, but has a distinctly different physiological effect, and is not nearly so poisonous, Inan examination of some commercial specimens of aconitine, the authors found large proportions of amorphous alkaloids present, and specimens of aconitine salts were found, in nearly every case, to be chiefly napelline salts containing small quantities of aconitine compoun The Aconites and Aconitines. E. Richards and F, A. Rogers arrive at the following conclu- sions :— The best material for the preparation of aconitine is the fresh root of Aconitum Napellus, The alkaloid resides chiefly i in the cambium layer, the fibro-vas- 3 cular bundles, and the sieve ducts, " Pure aconitine crystallizes in thin, flat, hexagonal prisms with acute ends. that two isomeric Saves of aconitine exist ; for aitin > and 8-aconitine are are suggested. APPENDIX. 91 The composition of aconitine corresponds to the formula H**N?0%2, which contains twice as much nitrogen as the mula hitherto accepted. The proportion of alkaloid in the root is as follows :— _ Aconitum Napellus, fresh ae ee di dried Bipanese booiite me ee ie O07 fhe method for the preparation of aconitine, recommended by the hors, is as follows :— oe aered tubers are macerated from three to four days with “0 “ with zanail eat of dilute sulphuric acid. The fusel ed ether driven off by heat. The alkaloid is Precipitated from id solution by solution of sodium carbonate, collected on a pressed between limestones, and then spread on bibulous and allowed to dry at ordinary temperature. The dried then boiled with pure dry ether, and the filtrate set aside lize; the crystals are redissolved in a small quantity of emove a gum-like body. toxicity of e-aconitine is stated to be only one-sixth of that of tine. (Chemist ands Druggist, Feb. 7, 1891, 205, and Feb. 1, 242, 243.) eaE +N 0), or Dunstan and Ince (C*H**NO"™). They state heating with water to 150° C., or by treatment with alcoholic oe aconitine does notat once yield benzoic acid and aconine ; but _ 1 addition to benzoic acid, methylic alcohol and another acid oduced. The authors state that by boiling aconitine with water ¢ at first produced a salt of anew base, which crystallizes liquid cools, and this product is described by them as : -picraconitine, This is represented as being formed by ysis— HNO" 41120 =0""H*NO" +0°H"0". 92, APPENDIX. By continuing the boiling a further alteration is effected according to the equation— C**H®NO” + H?O=C**H*’NO?° + CH°OH. Picraconitine. Napelline. Methyl alcohol. The formation of aconine is represented as constituting a third stage of alteration as follows :— C**H* NO” +H*0O—C*##H*NO? + C20*H?, Napelline. Aconine. Acetic acid. The authors suggest that it is still doubtful whether the acid pro- duct of this final change is acetic acid or acrylic acid, and that, in the latter case, the formula of aconine would be C?*H* + NO? From the production of mehtyl alcohol in the decomposition of aconitine when heated with water, it is inferred that aconitine is analogous to cocaine, and is to be classed with the acid esters, either as an acetyl or an acryl ester of benzoyl aconine, while aconine itself would he a derivative of a ena as lata quinone. (Journ. J. prakt. Chem., xlv., 604.) Note on Mishmee Teoeta and Bee (or Poison). ' These roots are procured on the: range of hills inhabited by the Mishmee tribe, and annually in the cold season a large supply is brought down to the plains, and the Malajans here, who are princi- pally Marwar-people, give in exchange for them beads, salt, coloured woollen and cotton cloths, &c., &c, The Mahajans state that these articles are readily purchased in Central and Lower Assam. The Natives here use the Teeta as a medicine in colic, ophthalmia, headache, and fever, The Bee or poison, which is brought down by the hill-tribes, is parboiled with a view to prevent its cultivation in the plains, It is generally employed by hunters for killing wild animals. Mishmee Teeta as a remedy for Colic.—Take 20 grains of Mishmee Teeta, 10 to 12 whole grains of black pepper, about 10 grains of The whole is to be masticated and washed down with a small APPENDIX: 93 x Mishmee Teeta asa remedy for Ophthalmia and Heailache—Take _ 2dvrachms of Mishmee Teeta and grind it with sufficient water to 3 form a paste, which is to be applied round the eye twice a day. - For headache it is applied to the forehead and temples, q _ Mishmee Teeta as a remedy in Fever,—Take 1 drachm Mishmee _ ‘Teeta finely powdered, and mix with half a pint of cold water. To ___ be taken daily in two doses, Purgatives are never used by the hill- tribes, Mishmee Bee (or poison) employed by hunters.—Take 2 or 3 _ drachms of Mishmee Bee finely ground, and mix with any acid _ glutinous vegetable pulp, so as to form a thick paste, which is to be _ applied to the head of the arrow and allowed to dry in the shade, The glutinous substance generally used is the pulp of a sour fruit called Owe Tangah by the Assamese and Chultah in Bengali (Dillenia Speciosa). I imagine it is preferred in consequence of its acidity _ preventing a flow of blood from the wound, which would wash away the poison, (By the Medical Officer, Chyckwah, Upper Assam, June _ Als, 1842.) Delphinium Zalil. Aitchison (Notes on Products of W. Afghanistan and N.-E. Persia, Pp. 55) says :—** Yellow Larkspur, asbarg, aswarg, isbarg, isbarag, tsparak, sparak, sparig, jalil, zalil; the flowers, gul-i-zalil, gul-t-jalil, A perennial herb, with a thick short woody rootstock, from which several annual shoots spring ; these are from one to two feet in height, each usually bearing a terminal spike of exquisite yellow flowers. When the flowers are at their best, the annual shoots bearing the spike of inflorescence is broken off close to the root; these are collected together, and then laid in heaps, usually on the roofs of the houses, to dry. In two or three days they are sufficiently dry, when the twigs are shaken over a sheet ; on this all the flowers tumble off, and are collected, either for local use or exportation. The petals are of commercial importance, yielding a valuable yellow dye for silk, and are exported for this purpose in large quan- tities to, Persia, Turkistan, Afghanistan, and India. The dye is easily obtained by simply boiling the flowers in water; in decoction the silk is dipped. ‘The dried stems also yield a dye upon being boiled, but this is poor in comparison with that yielded by the flowers.” : a YN FST a a AE Sy Peo a eee ee ae ee er ae 94 APPENDIX. In the Dret, Econ. Prod, of India, iii., 70, it is stated that in Multan the flowers are used along with Akalbér (Datisca cannabina) and alum to dye silk, giving a sulphur-yellow colour known as gandhak?, and that they are also used in calico-printing. Their price in the Punjab is said to be Rs.27°5 percwt. This dye is alluded to by Mr. Leotard, Dr, McCann, and Mr. Wardle, but under the name of D. Ajacis. The Hellebores of the Ancients.* Drugs prepared from hellebore were so famous amongst the an- cients as a remedy for madness, and, indeed, for many other ailments, that the plant has acquired for itself a literary as well as a botanical interest. Pliny gives a list of them quite worth the notice of adver- tisers of patent medicines. We know that different species have been used in different countries for their medicinal properties, which are, perhaps, essentially the same in all of them, though varying in strength. The hellebore of the modern English Pharmacopceia is the root of Helleborus niger, the common Christmas Rose, In Germany, H, viridis, the green hellebore, is said to be preferred, and from its frequent occurrence in England in the neighbourhood of old ruins, we may infer that it was formerly used here. At Constantinople a popular drug, called Zoptane, is made from H. orientalis, which is common on the mountains of Eastern Turkey. In Gerard’s time, our native H, fetidus, the rankest of all the genus, was employed medi- cinally, though known to require great caution in using, and it is still retained in veterinary practice for outward application. The physicians of ancient Greece, who for some centuries before and after the Christian era were famous throughout the civilized world for their skill, were very fanciful about the locality from which the herbs used by them were collected. The kind of herb might be the same, but when gathered on a particular mountain or in a parti- cular forest it was thought to have additional virtue. Drugs of the same name were classified as first, second, third or fourth quality, according to the source from which they came, and were priced and trusted accordingly. Hellebore was of two kinds, distinguished as black and white. The best black came from Mount Helicon, and the best white from Mount Gita. The town most famous for its prepara- tion Hon was called Anticyra, but this name was ambiguous. From the Gardeners’ Chronicle, January 2. £ et APPENDIX. __ 95 There is a well-known passage in ‘The Art of Poetry,” written by the Roman poet Horace, in which he says, that to gain a reputation im, and must never have his hair cut. Multiplying by three vas a common superlative figure of speech in Latin, as in any her languages, and perhaps Horace meant no more than this ; but, on the other hand, he may have known that there were in Teece three towns named Anticyra, and possibly they were places where the drug hellebore was prepared. One Anticyra a3 on a narrow strip of the land of the Locrians, between 4tolia and the sea. Strabo, an ancient writer on geography, and ivy, a Roman historian, both mention it. It was taken by the ans in the second Punic war, and given over to their allies, the ality, was used to adulterate the better Parnassian kind. There as another Anticyra in the south-eastern corner of Thessaly, iree or four miles from the sea, near the base of Mount (Cita and famous pass of Thermopyle, but we do not hear of this town as ducing hellebore, except on the slight authority of the lexi Ographer, Stephanus of Byzantium, who lived in the sixth century of our era. The third Anticyra, the only one which ve know to have been famous in classical times for th Manufacture of this drug, was situated on the southern coast of Phocis, not far from the base of Mount Parnassus, and within a few miles of Mount Helicon, The position of it is well known, and it is “ew named Aspra Spitia; it was not an island, as Pliny and others have wrongly said, and never can have been so in historic times ; t it stood ona peninsula and had a good harbour. In Horace’s y it was a place of resort for insane or epileptic patients, who went to take a course of hellebore under resident physicians. Hence, 0 say, “ You should go to Anticyra,” was a polite way of telling a man he was a fool. Amongst others who had gone through this medical course there, Pliny mentions the philosopher Carneades, who vent there for intellectual training, before publicly declaiming against dogmas of the Stoics, apparently supposing that a medicine which ‘make madmen sane would make sane men still wiser. Also usus, a famous popular leader of the Romans, was cured there of sy. The same writer adds that this drug, which retained its 96 APPENDIX. virtue for thirty years, and once was thought so formidable, had now become so “ promiscuous”’ in its use that students often took a dose of it to sharpen their intellect when they were puzzled by difficult passages in their reading—a valuable hint, by the way, for can- didates before a competitive examination! I recollect a virtuous freshman at Cambridge, who, with a similar object, laid in a large stock of “ Reading biscuits,” which he saw advertised in a window! The next question is, what were the kinds of hellebore called black and white, and found respectively on Mount Helicon and Mount (ita? We ought to be able to answer this, because Edmond Boissier has told us, in the preface to Flora Orientalis, that, thanks to the labours of the botanists, Orphanides and Heldreich, the flora of Greece is now better known than that of any other country within the scope of his work. The hellebore which is found to prevail on Mount Helicon, Mount Parnassus, and the neighbouring country is one to which E. Boissier gives the name of H. cyclophyllus, It is inter- mediate between H, viridis and H. orientalis, having been confused with the latter both by Sibthorp and by Heldreich. Perhaps it is not in cultivation in England, but it is described as being taller and having larger flowers and broader segments to the leaves than the green hellebore, which in other characters it resembles. As for the white hellebore, it is evident from the vague descriptions of Theophrastus and Pliny, that neither of them knew a living hellebore by sight, but Pliny says that he had been told that the leaf of the black hellebore was of the shape of a plane leaf, but divided into several segments, and that the white hellebore had leaves resembling’ those of the beet, and deeply channelled at the back. He attributes to it a bulbous root like that of an onion, with fibrous tunics. -Ancient and modern botanists have generally identified this ’ with Veratrum album, which is figured in Gerard’s *‘ Herbal” as the white hellebore ; but perhaps the best evidence is that of Heldreich, who explored Mount (ita in 1879, and found /’. album growing there in abundance, confirming his previous opinion that this was the white hellebore of Seecpbrastas. The different effects of the two kinds of _ hellebore taken medicinally, as recorded by ancient authorities, cor- respond with modern experience ; the black is a powerful cathartic, and the white a strong emetic. This is a summary of all that is ‘likely ever to be. known of the famous hellebores of the — t, Pharm. Jae Jan. fee: ‘1892 oe APPENDIX. 97 We have never met with any kind of hellebore root in the Indian ars, nor are any of the genus known to grow in India; still, all Indian Mahometan works on Materia Medica contain an account of hellebores of the Greeks, which hasbeen copied from the writings he Arabian physicians, and which is mostly a reproduction of what ic scorides says mepi AAcBdpou Aevxov and zepi EMAcBdpov peAanos the. erarum album et nigrum of the Romans. The Arabs call these ar unt ss Kutaki, see Vol. II, p. 10. MAGNOLIACEA. mstituents of Star-anise. Be cctations of volatile oil, fixed oil, and ash gave i : owing percentage figures :— las Volatile Oil. Fixed Oil, Ash. fe Osrpels > oer pe 2-81 Si 3°00 22°9 : — et 15-40 91:7 2:46 : volatile oil consists chiefly of anethol C°H*(OCH*)C*H®; small quantities of terpenes, safrol C°H*(O®CH*)C°H*, the thyl ether of hydroquinone C*H*(OH)OC?H’, anisic acid L (OCH*)COOH, and a complex aromatic substance yielding upon ation veratric acid and piperonal. The fixed oil contains the eonetitnents along with cholesterin and derivatives of phos- acid. Inthe aqueous extract is found protocatechuic acid shikiminic acid C’H'°O', which by nascent hydrogen iodide is ed into benzoic acid. Sugar was not found in any appre- quantity, the sweet taste of the fruit, therefore, depending the volatile oil. Nitrogenous bases could not be detected, Ostwald, Arch. der Pharm. 1891, pies Michelia Champa enol. Si csihes a kind of camphor, ae champacol, obtained champaca wood by distillation with water. After purification it at 86—88°C., has the form of long white felted needles, has ¢ when pure, but when kept in an impure state becomes: er the agreeable odour of the wood. (Berichte, 98 APPENDIX. MENISPERMACEZ. Constituents of Calumba Root. M. Bocchiola (Chemist and Druggist, Jan, 10, 1891) gives the following percentage composition of the cortical and woody portions of the root :— Outer part. | Inner part. Water ~ ..: vas we ape seers AS Ses 13°00 14:00 Ash aa ve ve eae! ag eee 5:00 6:00 Ether extract ae te ee fee ce as 0:70 0°80 Alcohol.extract . a ot de es a 3°89 3°86 Proof Spit extract has wis ~~ te aa 17:96 17:80 Calumbine — ae oy fas tes 1°42 1-90 Do. by titration ... a ee oe ae 0:98 1-38 Berberine ... es 2S a5 dee ae veg 1:43 0°72 o. by titration .., “et ete on vee 2°95 The percentage composition of the ash was :— Silicie acid 14°13 and 7°42, phosphoric acid, as an iron salt, 6:11 and 161, phosphoric acid, combined with alkali and earthy bases, 5-04 and 12°63, in the outer and inner parts of the root. The author found old roots to contain as much as 2°07 and 2°63 per cent. of calumbine, and 2°05 and 1-02 per cent. of berberine, showing their superiority over the younger roots. BERBERIDEZE. Berberis vulgaris, Linn. Snttohieon (Notes on Prod. of W. Afghanistan and N.-E, Persia, p. 25) has the following notice of this plant:—“ The Barberry, 777, jirkhdr, zer-khdr, zir, zir-bar, xir-balak; the fruit, zirishk, sirishk. . Avery common shrub, growing at an altitude of 2,000 feet and upwards, from which is largely collected the fruit ; this is consumed locally, as well as being exported in some quantity to India, where it is highly appreciated by the natives as a condiment, Usually the contains no seeds; it is then much more oval, longer, and of a = much lighter colour than that which has seeds. On reaching the e ea the fruit or preserve is called zirishk-tursh, to distinguish pis. ede from small, dried, black grapes; the latter are our currants, or « ees. From tke roo of th = pd lata ah ies at a as APPENDIX, 99 _ Berzerts is obtained an extract called Ibrén; this is a yellow dye, which is also employed in medicine as a local application to inflamed eyes.” Podophyllum emodi. We have met with the root in the plains in the possession of a pilgrim from Kedernath. He called it Mémirdn, and greatly valued it as a remedy for ophthalmia, his small stock of four or five roots was carefully wrapped in several covers of silk. Analysis of the Resin of Podophyllum emodi. _ Ash The etrolenin ether extract was yellowish-brown in colour, semi solid 7 in consistence, and waxy in odour. The taste was nauseous, recalling 3 _ eroton oil. In absolute alcohol it was wholly soluble with strongly acid reaction. On spontaneous evaporation of the alcoholic solution, _ a yellow transparent mass was left at the bottom of the beaker, . _ while on the sides the deposit was yellowash- ae. = apna oe a microscopic examination, it appeare spirit solution, on spontaneous evaporation, deposited soft orange resinous matter, while some white deposit separated on the sides of the capsule. This was found to consist of oil globules, and a few minute needle-shaped crystals. In addition to oil and resinous matter possessing an acid reaction, the presence was also detected of an alkaloidal principle soluble in ether, which afforded marked indi- cations with the usual reagents. With Fréhde’s reagent no change Was observed in the cold, but a dirty blue developed on gently _ Warming, The portion of the petroleum ether extract insoluble in __proof spirit was boiled with alcoholic potash, the solution evaporated to dryness and treated with water. The aqueous solution was turbid _ from the separation of brown flocks, The turbid solution was agitated With petroleum ether. The ethereal extract had a camphoraceous “es terebinthinate odour, was of an orange colour, and had a melting point of 62°C. Jt was not furtherexamined. The aqueous Soap solution was decomposed by dilute sulphuric acid and agitated with ether. The ether extract was converted into a Iead soap and Yeagitated with ether. The soluble lead soap, after separation of prepared solution of nitrate of mercury, it solidified to a yellowish 116 APPENDIX. mass. The insoluble lead soap, after separation of lead, afforded a. residue which was solid at ordinary temperatures, and had a melting point of 48°. Neither of these fatty extracts was pure, and no attempt was made to ascertain whether they consisted of single acids or mixtures. The presence’ of glycerine was~determined in the original aqueous sulphuric acid solution. The aqueous acid solution of the alcoholic extract of the roots, after treatment with petroleum ether, was agitated with ether, The ethereal solution was allowed. to evaporate spontaneously, and the final desiccation conducted over sulphuric acid, The non-crystalline residue was dark brown and tacky with tar-like odour; it amounted to +123 per cent., caleu- lated on the roots containing 6°23 per cent. of moisture. Warme with distilled water, a part of the extract dissolved, the solution — the following reaction :— Reaction, niger acid, e®Cl” gav a dirty greenish coloration, passing sehity't to dirty brownish. AgNO", alight turbidity ; on warming Ag. reduced. Aqueous NH®, orange yellow coloration. _ Acetate of lead, dirty yellowish, white ppt. Gelatine, no precipitate, KCN., no reaction. That portion of the ether extract insoluble in warm water was treated with aqueous NaHO, and the dark brown solution which resulted agitated with ether. The ether solution exhibited slight fluorescence, and on spontaneous evaporation afforded a yellow crystalline deposit, which appeared as needles and rosettes on microscopic examination. By treating this residue with proof spirit a certain amount of neutral resinous matter of a yellow colour was separated, This was precipitated on dilution with water. The insoluble crystalline residue afforded no crystalline sublimate when heated between watch glasses. The aqueous soda solution of the ether extract was mixed wit dilute sulphuric acid and reagitated with ether, The ethereal extract - was of a yellowish-brown colour, strongly acid in reaction, and had the properties of an acid resin, The tartaric acid solution of the alcoholic extract of the drug was now mixed with a very slight excess of sodium bicarbonate and again agitated with ether, After agitation and on subsequent standing, small quantity of @ white crystalline substance separated, which ie eT Se eee "was finally agitated with amylic alcohol. APPENDIX. ] 1 7 floated on the water stratum below the ether. The ether was sepa» rated and allowed to evaporate spontaneously, the extract amounte to 048 per cent. ; it formed a yellow transparent varnish on the sides of the capsule, while at the bottom it was white, chalky, and indis- tinctly crystalline; odour, aromatic. The chalky deposit consisted of some irregularly-shaped plates and amorphous particles. The yellow varnish-like residue was easily soluble in proof spirit, but neither this portion nor the chalky deposit afforded any reaction with alka- Joidal reagents. The chalky deposit treated with concentrated H’°SO* afforded a yellow solution in the cold, changing to pinkish on standing for some time, but on heating the pink colour was developed rapidly. Nitric acid, no reaction, Fréhde’s reagent, greenish in the cold, passing to blue on warming. Ferric chloride, no reaction Heated with dilute aqueous H?SO* and the solution neutralised it reduced an alkaline copper solution on boiling. en agitated with water, considerable frothing was noted. A small amount in- jected, mixed with water, into a cat’s stomach induced no symptoms When applied to a cat’s eye, there was no change in the size of the pupil observed. The yellow varnish-like deposit separated from the chalky deposit, by the action of proof spirit, when injected into a cat’s stomach caused the animal to vomit once a small quantity of frothing liquid ; one formed stool was also passed, but no other symp- toms were noted, The varnish-like residue, when applied to the tip of the tongue, produced a slight sensation of tingling or numbness, which lasted for a short period, and could not be mistaken for the symptoms induced by aconitine. The alkaline aqueous solution of the alcoholic extract was next agitated with chloroform. The extractive was yellowish -brown, with an odour like that of gum benzoin, and amounted to 064 per cent. In cold proof spirit it was partly soluble, the solution on spontaneous evaporation affording a residue which contained a few microscopic plates. The residue insoluble in cold proof spirit was pale yellow and soluble in boiling proof spirit. On spontaneous evaporation a white crystalline deposit was obtained, consisting of bundles of rods and a few plates, The residue frothed when agitated with water, and when treated with concentrated a ee Ton a - i i solution © coholic extrac’ coloration. The alkaline aqueous Ths’ axel meen 1-582 per cent,, and formed a transparent, soft, viscid residue of 118 APPENDIX. a reddish-yellow colour, non-crystalline, and frothing considerably with water. In warm water it dissolved, forming a clear solution, which became turbid on cooling. Anattempt was made to decolourise the aqueous solution by agitation with purified animal charcoal, but very little colouring matter was thus removed. As neutral salts, as NaCl, MgSO*, gave a white curdy precipitate from the aqueous solution of the extract, an attempt was made to separate the saponin-like principle by saturating the watery solution with MgSO?’ ; it was found, however, that the flocks agglutinated together, forming a sticky mass, and filtration was impossible, Baryta water was next used for separating the principle. With this object the amylic alcohol extract was dissolved in water and excess of aqueous barium hydrate added. The turbid mixture was then filtered (filtrate A), the precipitate was washed with baryta water and transferred to a beaker, water added, and CO? passed for a considerable time. The turbid mixture was then evaporated to dryness on a water-bath, and exhausted with rectified spirit, the filtered alcoholic solution was evaporated to dryness, and left a scaly, friable, shining residue, which afforded the following reactions:—With concentrated H?SO* a yellow coloration, changing to red. Concentrated HNO’, yellow. In concentrated HCl it dissolved freely, forming a faint pinkish coloured solution, the colour deepening on the application of heat, and — a few flocks separating. In strong acetic acid it was also readily soluble, forming a colourless solution, no change being induced by the subsequent addition of potassic dichromate. When heated with aqueous phosphoric acid it did not yield a clear solution, no colour developed, and no odour, With aqueous ammonia it was sparingly soluble; no precipitate with acetic acid; the ammoniacal- solution frothed on agitation. Boiled with dilute HCl, it afforded a solution which reduced alkaline copper. The amount of principle presipitated by baryta was small, and though this principle afforded some of the reactions of saponin, it seemed probable that the greater part was still present in the filtrate. A fresh portion of the original amyli¢ alcohol extract was dissolved in water, and treated with lead acetate, which afforded a white curdy precipitate, after separation of lead by H?S, yielded extracts which frothed strongly on agitation with water, and gave ‘Some of the reactions of saponin. The amount of extractive yielded. was, however, small, and it appeared to us that probably both the APPENDIX. 119 lead precipitates were either unstable compounds of a saponin with that metal, from which the greater part of the principle could be separated by washing, or that they consisted chiefly of easily soluble lead salts of a saponin, or of a lead salt of a saponin mechanically mixed with a saponin precipitated by the action of lead acetate, in _ the same manner as we have found certain neutral salts to act. _ But, on the other hand, it was possible, assuming the existence of more than one saponin-like principle in the plant, that one saponin formed a stable and insoluble lead compound, the other an unstable or soluble salt, And similar remarks might also apply to the barium hydrate precipitate. _ As bearing on these points the following experiments were made:—The amylic alcohol extract was dissolved in water, excess of lead acetate added, and the turbid mixture repeatedly agitated with amylic alcohol, During agitation the greater part of the precipitate agglutinated, forming a yellow viscid coating on the bottom and sides of the bottle. This deposit appeared to be very slightly soluble in amylic alcohol. It was soluble in acetic acid, and the aci if it contained any saponin-like principle or not. It was first filtered, and then evaporated to dryness on the water-bath. The residue was yellowish and brittle, and contained a small quantity of lead. amount of extract was far larger than that obtained from the viscid deposit after decomposition with acetic acid, Lead was removed by dissolving the extract in water and passing H’S, The filtered solution was then evaporated to dryness, the residue reduced to fine powder was white and free from odour. It afforded the following reactions :—With cold water it formed a slightly opalescent solution, which frothed considerably on agitation. Concentrated H*SO* : with violet at the edges on standing, and green on the addition of potassic dichromate, Concentrated HINO? colourless, yellow on the addition of dichromate, 120 APPENDIX. and changing to blue on standing for some time, In concentrated acetic acid, readily soluble, forming a colourless solution, Soluble in dilute ammonia, forming a solution which frothed, and from which acetic acid gave a white precipitate on neutralisation, Caustic soda, similar reactions to ammonia, Tannic acid, a white precipitate. Ferric chloride, a turbidity in the cold, which disappeared on heating, the solution being of a brown colour. On boiling with dilute HCl, dark brown, oily globules separated, and the solution reduced alkaline copper. This decomposition product did not appear to possess the properties of the principle described as sapogenzn, obtained by the action of dilute acids on ordinary saponin. The ash amounted to ‘47 per cent. ; it was free from lead. To determine the ultimate composition of this saponin, it was dried over sulphuric acid in a vacuum, and the combustion made in an open tube in acurrent of oxygen, and the results afforded the following percentages :— Exp. 1. Exp. 2. ean. Carbon .,. wee 60°92 61-18 61°05 Hydrogen wie Peo 8°74 8°84 Oxygen ~ OUIO 30°08 30°11 100°00 100-00 100-00 From these percentages a formula C**H**O"? was deduced— Calculated for 0327754012, Found. Carbon... eee 60°95 61°05 Hydrogen ... coe 8°57 8°84 Oxygen ... as 30°48 30°11 100°00 100°00 In another experiment a somewhat different mode of extracting the saponin was adopted. An alcoholic extract was obtained from another sample of Bikhma, no acid being used in the extraction. ‘The alcoholic extract was mixed with water and directly extracted with amylic alcohol, without previous treatment with pet: ‘ether, ether, and chloroform. The amylic alcohol containing the -erude saponin was separated, filtered, and then repeatedly agitated ‘with aqueous basic lead acetate. During agitation the yellow viscid APPENDIX. : 121 matter, ‘hlready mentioned, separated on the sides of the bottle, The agitation with basic lead was continued for a considerable time, until colouring matter ceased to be dissolved. The amylie alcohol was then allowed to stand for some days, filtered, and evaporated on a water-bath. The extract was next taken up with water, and lead removed by H*S. After filtration the solution was again evaporated and digested with ether. The saponin extracted in this manner had : B faintly yellowish colour, and contained 6 per cent. of ash free from lead. After drying over sulphuric acid in vacuo, the following results Were obtained on ultimate analysis:— Exp. 1 Exp. 2 Mean Carbon Peg te Y: 60°21 60°165 Hydrogen 8°35 8:54 8:445 Oxygen .. 31°53 31:25 31:390 Some of the saponin used for the last analysis was subjected to a farther process of purification. It was dissolved in amylic alcohol, and the solution repeatedly agitated with aqueous barium hydrate. _ On evaporating the amylic alcohol solution to dryness, and heating f the powdered extract with ether to separate traces of amylie alcohol, _ the saponin was left asa white powder which contained °308 per eent.of ash. On ultimate analysis, the following percentages were _ obtained, the saponin being dried %n vacuo over sulphuric acid:— Exp. 1. Exp. 2. Mean. Carbon ... 6 BE 59°82 59°86 - Hydrogen... .. 8°64 wae foe : p28 ee 665 ae = Oxygen 3 10060 -:200-00 100-00 It seems likely to us that the last sample of saponin isolated was the purest of the three examined, though we are not prepared to definitely assert it was a pure saponin. We have adduced some evidence which tends to indicate that at least two saponins exist in false -Bikhma, and it is possible that the method we used for separation = 122 APPENDIX, afforded a mixture. It was our intention to have determined the ultimate composition of the saponin in combination with lead, to which we have referred as a ‘‘viscid yellow compound,” and to have examined the product yielded by the hydrolysis of the saponin, but we were unable to complete our research. The results of the proximate analysis of the false Bikhma may be stated thus :— Moisture ... Se Os Petroleum ether esieent a ae LA7s- Acid ether extract ee ves “123 Alkaline ether extract .,. ae ee Chloroform extract Amylic alcohol extract ... ae Los We also append the results of an analysis of the specimen of A. palmatum referred to above. Our 100 parts afforded the follow- ing results when examined by Dragendorff’ s method :— Petroleum ether extract,,. eas “040 Ether extract oe *048 Absolute alcohol seleand: im ade Water extract .,. eet dice AU An alcoholic extract affords the following percentages :— Petroleum ether extract ... ae as ... 946 Acid ether extract oe ag ee eee Alkaline ether extract. ‘sie ae ie Fe | Amylic alcohol extract .., sos sve ‘an OED The compositions of these extracts we were also unable to examine. We may summarise our results by stating that the most important constituents of false Bikhma are saponin, and as bearing on the identification of the plant which yields the’ drug, we would refer to itchison’s “Notes on Products of Afghanistan and Persia,” in which it is stated that the name Bekh is technically applied to the root-stocks of Acanthophyllum macrodon and Gypsophila paniculata. These are both used as soaps, and ese false Bikhma may be Borived pon one of these plants. (Cc. J. Warden and Assistant 2 Chuni Lal Bose in“ Pharm. Journ’ October 15th, Usa APPENDIX. _ 123 = PORTULACEZ. 5 Chemical Composition of Portulaca oleracea. Water a few Bis a 92°61 Nitrozenons pereneen ee kes ee fei 2°24 eat... ‘xe oe sat a : 0°40 Non-nitrogenous extractive ses a Sek 2°16 Cellulose .., et ae . a i 1-03 Ash ihc ee one Pie ies 1°56 Ln dry eae Nitrog tee” ; eee ees ete 4°85 Be oasis vid - i sae --. «—a9'2S (Konig, Nahrungs Mittel, p. 147.) TAMARISCINEA., Remarks on the substance called Gez or Manna found in Persia and Armenia. At entertainments in Persia a sweetmeat called Gezangabeen is usually met with, the pleasant taste and other singular properties of Which, as well as the mystery that involved its origin, excited my curiosity to know if it were an animal or a vegetable production. The principal ingredient in its composition is a white gummy € appearance and feel of common dough, though a little more hard, Jt is at the same time both adhesive and brittle, for any attempt to 2 mode, however, generally practised of breaking it for use is by Placing one cake on the palm of the hand somewhat hollowed and triking it with the other, when the blow occasions it to fly into Several pieces, whose edges, rather eusien Sain appear smooth and polished like broken glass. - Collection. —Before daylight we marched from Khonsar, and, on ing the boundaries of the town, deviated from the main road as ve had been directed, and began rambling amongst the bushes on the ace of the mountain on our right, diligently looking for the gez. The we had received were to examine the bushes closely, as the 124 APPENDIX. object of our search was not easily visible at any distance ; too much confidence, however, in the knowledge of our servants and guide who, with true Persian effrontery, asserted they were familiar with the appearance of the gez. in its natural state, nearly occasioned us a complete disappointment. We had relinquished the pursuit in very ill-humour, to resume our journey, when we met, as chance would have it, two peasants proceeding to the spot we had just quitted : as usual, we accosted them, andwere not alittle pleased at hearing they were the people whose occupation it was to gather the gez. These men were furnished with a stick three-fourths of an inch in diameter and curved at the further extremity, which was covered with leather, and a kind of oval leathern bowl, near three feet long and two broad, with a handle to it, resembling an egg-shell cut in two longitudinally. Besides these, they had a sieve suspended from the right side, to free the gez from the insects and small pieces of leaf that generally fall with it when first beat from the bush: the bottom of the sieve was of coarse woollen cloth, The countrymen were easily persuaded by a trifling present to fall immediately to work and show us a specimen of their employment. They turned off the road a few yards amongst the bushes we had just quitted, and placing the leathern receptacle underneath, they beat the bushes on the top with the crooked stick; in a few minutes they had obtained a handful of a white kind of sticky substance not unlike hoar frost, of a very rich sweet taste: this, after being purified by boiling, is mixed up into the sweetmeat before mentioned under the name of gezangadeen, ' Though the gez, when fresh gatheredfrom the gavan bush, admits of being sifted, stillin this original state it is brittle and adhesive at the same time, qualities for which it is so remarkable after its preparation as a sweetmeat. If pressed, it sticks to the fingers ; but on being smartly struck with a bit of wood separates easily into small grains like lump-sugar. It is in this state in cool weather, or when the thermometer does not exceed 68° F.; but liquefies on being exposed to a higher temperature, resembling "white honey both in colour and taste, The shrub on which the gez was found is called the gavan; it mere: from a small root to the height of about two feet and a half, into.a:cizpular fotm.et the top fram three to four fect and’ APPENDIX. 1 9 5 ‘Spread all over the tender branches like white uneven threads, with innumerable little insects creeping slowly about. These little creatures appeared to derive their subsistence from the leaves and young bark of the bush they inhabit; and this is the opinion of the country people. They are either three distinct species of insects, or one in three different stages of existence: one kind is perfectly red, and so diminutive as to be scarcely perceptible ; the Second, dark and very like a common louse, though not so large ; their ‘occupation every third day for twenty-eight days during September, A journey, which I subsequently made to Baghdad, con- und in the range of mountains running through Koordistan, dividing Persia from Asia Minor and Mesopotamia, where it is ealled ha by the Armenians, and said to be exported in quantities through Erzeroom to Constantinople. (By Captain B. Frederick, from the « Transactions of the Literary Society of Bombay,” Sep- tember 28th, 1813.) _ Note.—The gavan is Tamarix gallica, var. mannifera, Ehrenb., and the aphis, ch feeds upon it and produces the gez, is the Coecus manniparus of Ehrenberg _ *he name Gezangabeen is loosely applied by the Persians to thé true manns Obtained from Cotoneaster nummularia in Korasan, the correct name of which is Shirkhisht, TERNSTREMIACEZ. Camellia theifera, @rif. _ Tea seeds contain 35 per cent. of a somewhat thinly fluid, taste- Jess, inodorous oil, of a straw to amber colour, which resembles olive — 126 APPENDIX. oil, At 15°C. it has a sp. gr. of -9270; at 38°C. it forms an emulsion and solidifies only below—~5°C. Itis scarcely soluble in spirit of wine, and very sparingly in ether. Chemically, it consists of 25 parts stearin and 75 parts of olein. In China it is used as a table and lamp oil and for the manufacture of soap, for which it is specially well adapted, yielding a beautiful hard soap. Tea oil has been used in China for a very long time, but has been only recently introduced into commerce. C. oleifera and C. drupifera yield oil for household purposes similar to the above. (Brannt.) Caffeine and Theine: their identity, and the reactions of Caffeine with Auric Chloride. © In consequence of the conclusions of Mays (Journ. Physiol,, 7, 458; » Therapeutic Gazette, 1866, 587), and morerecently of Lauder-Brunton and Cash (Proc, Roy, Soc,, 42, 283; Journ. Physiol,, 9, 112), that the physiological action of theine obtained from tea differs in certain respects from that of caffeine obtained from coffee, the authors have searched for evidence of isomerism in these bases, the existence of which is not put beyond doubt by the chemical comparison of them which has hitherto been made, Having extracted theine from tea and caffeine from coffee, it is shown that the two substances exactly resemble each other, and melt at precisely the same temperature, viz., 234°5 (corr.). From each base the crystalline aurochloride (C°H?°N*0?, HCl, Au Cl'2 H*-0) was prepared, and these two salts both melted at 242-5 (corr.). When dried at 100°, they both lost the equivalent of two molecular proportions of water, and the anhydrous salts melted at the same temperature, viz., 248°-5 (corr,), The analytical data corresponded with the formule given above. The complete correspondence in the properties and composition of the aurochloride is satisfactory evidence of the absence of a structural difference in the bases. In order to further confirm the identity of the two substances, a specimen of each was converted into the mercuric chloride compound (O°? N*0?, Hg’), a stable crystalline salt. Both preparations were foundto melt at the same temperature, viz., 246° (corr.), and to exactly correspond with each other in other respects. The complete identity of caffeine and theine having thus been _ demonstrated, the observed differences in their physiological action must be ascribed either to impurities in the specimens used, or to APPENDIX. t27 _ Variations in the animals employed in the experiments. The cireum- tains other bases than caffeine, the presence of traces of which Might be sufficient to account for the observed difference During the preparation of the pure aurochlorides for a comparison of their properties the pees obtained two new and interesting -auric derivatives of caffein _ When an aqueous solution of caffeine aurochloride is heated, a Yellow, flocculent. precipitate is gradually formed, which is insoluble aleohol, chloroform, and ether, but dissolves in hydrochloric i producing the aurochloride. The substance dried at 100° form pale yellow amorphous powder, which melts at 207° (corr.). ‘Aisne roved it to be aurochlor caffeine C°H%AuCl*)N*O?, a substance which one atom of hydrogen in caffeine is replaced by the group uCl?). It is pointed out that the ready formation of this remarkable compound from caffeine aurochloride by the loss of two molecular pro- rtions of hydrochloric acid—C*H'N*O*, HCl, AuCl’=2 HCI+ HA’ (AuCl*) N*O2—is better shown ee Medicus’s formula for caffeine, than by that proposed by Emil Fischer, since in Medicus’s mula the CH group which loses hydrogen is represented as_con- ‘iguous to the deubly-linked nitrogen atom, to which the auric- chloride is attached, _ By the reaction of an alcoholic solution of potassium chloraurate (KCl, AuCl*) with a solution of caffeine in chloroform, a salt, Crystallizing in the dark red needles, was obtained. This is shown to be caffeine potassium aurochloride (C°H**N*O?, KCl, AuOl*) which differs from caffeine aurochloride in containing potassium in the place of the hydrogen of hydrochloric acid. ‘This salt melts at 208° (corr.). It readily dissolves in alcohol and water, forming yellow Solutions which appear not to contain the salt itself, but its constituents, caffeine an potassium chloraurate. The salt is nearly insoluble in ether and chloroform, but prolonged contact with these liquids leads to its decomposition into caffeine and potassium choloraurate (W. R. Dunstan and W, F. J. Shepheard, from the Research Laboratory of the Pharmaceutical Society—The substance communication made, to the Chemical Society, December 15th, 128 APPENDIX. MALVACEZS, Altheea lavaterseflora, D0. Aitchison (Notes on Prod. of W. Afghanistan and N.-£. Persia, p- 9) notices it as a cultivated plant usually grown on the ridges between fields, It is grown not only for the showiness of its flowers, but for the petals, which are collected as they fall off the plant, and employed in local medicine or exported under the names of gu/-t- khatmi or gul-khairu, The seeds are also collected and sold as tukm-i-khairu, and the roots as reshai-khatmz. We have received the flowers from Afghanistan, where they are used as a substitute for those of A. officinalis; they are very mucilaginous. STERCULIACEZ, Heritiera littoralis, Dryand., Rheede, Hort. Mal, ri., t. 21. The seeds of this plant, common on the coast, have been substi- tuted for white Kola nuts, to which, when the chestnut coloured, papery, episperm has been removed, they bear some resemblance, but are a little larger and nearly orbicular, with a somewhat sinuous instead of an angular outline, Heritiera seeds are from 0:010 m. to 0015 m. thick, and have a diameter of about 0°04 m.; they are - eonecave on one side and convex on the other, and are composed of two cotyledons, one of whichis double the size of the other. Heckel and Schlagdenhauffen (Nouv, Remédes, 1887, p. 155) sia the following as the composition of the almond :— Out. .s oes ee is wae Gee ... 4366 Tannin and colouring matter ; we 4983 Sugar ... Se as ee —_ ae oles Sodium chloride oe ae Be gids cc ane Cellulose and starch .. ous ees ug ee or Albuminoids . a cei nea es is Lignin a Pees ae 5 wae: AOE Fixed salts... res ska eae oe . BOeo Loss ... Ae Ge sis 3 oo me 0-089 The ash contained traces of iron and manganese, oe consisted chiefly of phosphates and sulphates of lime, potash, and soda. No fo a as. und. The seeds are eaten in India, and it is evident ly si ‘that they have considerable alimentary value. — APPENDIX, 129 Sterculia alata, Roxb. Bedd. Fi, Sylv., t. 230, The kernels contain 45:27 per cent. of a bland oil possessing’ some ative properties, Eighteen kernels were eaten by one of us hout any symptoms being induced, hence Roxburgh’s statement he seeds under the name of Zoola are said to be eaten by ves in Silhet as a cheap substitute for opium is probably based lincorrect information, The-tree is one of the largest found in ngal, and seeds very freely; in our opinion the kernels form a t excellent substitute for ordinary almonds, which they resemble shape and size. Theobromine and caffeine were specially looked t with negative results, Sterculia scaphigera, Wall. These remarkable fruits are brought to India by Mahomedan lerchants from Java and Singapore by way of Karaikal and ‘agore, ae towns on the Coromandel Coast. They are called s-Mungoo in the Malay language, and are used as a demulcent Sterculia Gum. . J, H, Maiden, in an article on Sterculia gum (Pharm, Journ, RK. 381), shows in the ambenai table how suitable it is as a tute for Tragacanth :— Stereulia. Tragacanth. “! a, Colourless .. | @. Opalescent é. Granular jelly... b. Smooth viscid mass. c. Adhesiveness ab-| c. Adhesive. . sent or wae . : : i ng in dilute al-| Insoluble ss gee entirely dis- SolvV and| No change of colour. Canary- yellow colour, hich fades on cool- ing : : : dng in dilute acid. Soluble, pines ara-| Soluble, forming pectin J. EE. rr au a to) Whitish sae Formation of floating form in (see fuller state-| glairy mass. ment). oa Sterculia gum to yield to cold water only 3°14 per en chiefly of Arabin; 75'1 per cent. of the gum was 130 APPENDIX found to be Pararabin, The gum contained 16-6 per cent. water, and yielded 5°83 per cent. ash, Mr. Maiden draws attention to the fact that Pararabin is the chief constituent of the vegetable jellies known as Agar-agar, a Ceylon moss, both of which are used by the natives of India as an article of diet like Stereulia gum, and are supposed to be very strengthening. A sample of gum said to be from Cochlospermum gossypium was found by him to be similar to that of Sterculia, but as it had pieces of lace bark attached to it, it was probabl y Sterculia gum, . LINEA. Linamarin. A, Jorissen and E. Hairs (Acad. roy. de Belgique (8) 21 (1891), 529) have isolated a glucoside, linamarin, from the germs of Linum usitatissimum, The germs, coarsely powdered, were treated repeated- ly with boiling 94 per cent, alcohol, the latter recovered and the residue taken up with warm water, The resin and fat are — separated, and the aqueous solution treated with a slight excess of lead acetate. After filtration and precipitating the lead with H®S the | liquid is evaporated to a syrupy consistency, This residue is extract- ed with boiling alcohol, the solvent recovered for the greatest part, and the remaining liquid mixed with ten times its volume of ether under constant agitation, The residue remaining on distilling off the ether istaken up with water and this solution concentrated. Standing over — sulphuric acid for some time, the concentrated solution is converted into a crystalline mass of linamarin. For purification it is again — treated with ether and alcohol as above, Lastly, the principle is — dissolved in two parts of warm absolute alcohol, and the solution — cooled under agitation. The germs yield about 1°5 per cent. of — the glucoside, which forms colourless needles possessing a refreshing but very bitter taste, is soluble in water and alcohol, but almost in- | solubleinether. Concentrated sulphuric acid does not colour it; dilute — mineral acids decompose the glucdside into hydrocyanic acid, a fer- — mentable sugar reducing Fehling’s test, and a volatile compound 4 possessing some characters of ketones, and giving with iodine and | potassium hydrate the iodoform reaction, Boiling barium hydrate : iberates ammonia. Linamarin contains C 47°88 per cent., H 6°68 — Ber AS 5°55 per cent., O 39-89 per cent. (Am, Journ. Pharm., — APPENDIX. : ae 31 Growth of the Indian Linseed Trade. Dr. G. Watt (Dict. Econ. Prod, India, Vol. V., p. 76) shows thatthe ade has expanded from about 3 cwts. in 1832 to 8,461,374 ewts. 1 1888-89. : Erythroxylon Coca grown in India.* Several samples of Erythroxylon Coca leaves, grown in various - listricts in India, have been examined by Warden; the mode of ture, altitude, and meteorological characters of the district, the ind of soil and manuring, and the methods of curing being taken ~ into consideration. The alkaloid was estimated by Squibb’s modified hod: the dry pulverized leaves were moistened with alcohol fied with sulphuric acid, percolated with alcohol, the percolate d with acidified water, and extracted with ether, then rendered ine with sodium carbonate, and again extracted with ether. This act was washed twice with water, dried and weighed; the ounts of “crude alkaloid” so determined are given in the follow- Per cent. dry leaves. District ga grown. Moisture. a Fate : aklaloid. , young leaves ,. jo 6:18 6°71 1-139 mature leaves .. és 8°22 8°99 0883 ae 6-08 7-39 1:369 * ‘ 6°72 © 6°36 1671 : 4087 7-58 1-115 See | 9°80 12:18 1-022 571 7-62 0-610 10°05 12°64 0-571 aoe oo: wii. +» 249-251, 260-262, 273-276 ; Journ., Chem. Soc., March, 1889. 182 APPENDIX. The crude alkaloid was very faintly yellow, and in no case showed any tendency to crystallization, although attempts were made to induce crystallization by extracting at various temperatures, and without applying heat, and by employing different acids and solvents. * The allakoid obtained is, nevertheless, quite similar to cocaine from _ other sources in its physiological action, except that it seems to be more active. It dissolves readily in hydrochloric acid, and yields a soluble and insoluble platinochloride, the former containing 18°75, the latter. 18°88 per cent. of platinum; discrepancies from the theoretical are assumed to be due toa variable quantity of cocamine (Hesse, Am. Journ, Pharm., 1887, p. 455) in the alkaloid from Indian leaves. Both platinum salts yielded bases producing marked anes- thetic effects on the tongue ; Howard has observed that the insoluble platinochloride obtained from other leaves was devoid of this pro- perty (Pharm. Journ. and Trans., July 23, 1887). In oneinstance, stellate erystals of the base from the soluble platinum salt were obtained. Applying Williams’ method, the crude alkaloid showed 2°89 per cent. of impurity, but the precipitates were not crystalline. It is noted that after the addition of ether to the acidified alcoholic solution, larger deposits of the sulphur-yellow cocatannic acid were tained from those samples containing the highest percentages of alkaloids; it is hence suggested that possibly cocaine exists in the leaves as cocatannate, Methods of cultivating the plants are described: the leaves are first gathered 13 years after transplanting, sub quent] sufficiently mature; and, although the method of curing does not appear to affect the quality or quantity of the alkaloid obtained, nevertheless it is best, taking into consideration Paul’s experience, to dry them, soon after gathering, at as low a temperature as possible, and when dry and cold to pack them closely in air-tight chests, as they are very hygroscopic. The quantity of alkaloid produced increases with the age of the plants (which attain a height of from 2 to § feet) up to 10 years, and after 20 years a slight falling off is observed, although they are in their prime even when 35 or 40 years old. 1 4} JY WHCTOC VOL LUCY ale From the above results, obtained from plants and leaves of various ages, it would seem that, in India, neither altitude nor rainfall have ‘much influence on the proportion of alkaloid in the leaves. The ash, in vall. cases except one, was white, the exception being an ash of a APPENDIX, 183 reddish hue are side peat — nian A partial examination of some of th follow} i ae v or ton) K cal. as Samples from constituents. KHO, ee we| 44°42 29-26 “ Pee ee 19°13 gk es Ve ee 29°84 ge ee eee 31:36 that both nitrogenous and potash manures will probably be equired in the future to keep up the yield from the same plantation. Fruit of Erythroxylon Coca, ‘The fresh ripe fruit weighed, on an average, ‘158 gram each ; they re bright scarletin colour, and possessed a distinctly sweetish taste, though masticated at various times, no physiolgical action on the us membrane of the mouth was observed, Dried in vacuo over Iphuric acid, the original tint, was only slightly deepened, and this ethod of desiccation was employed in preparing the fruit for is. h granules and scarlet colouring matter. Next comes the pulp, _ of parenchymatous cells, containing starch and granular Then the shell, composed of an outer layer of stony cells, bone cells, which are of considerable length ; within this layer is aad of scalariform vessels, and then several rows of pitted vessels. n the almond, the cells of which are full of starch. The petroleum ether extract was a deep reddish semi-solid residue, , on microscopic examination, was found to contain lamelle and of aclaret colour. It contained no alkaloid, and melted at °C. A portion was saponified with alcoholic potash, and when itated with ether. At 189—191° this extract a to aclear quid, which cooled to a brittle transparent m Heated watch-glassesfor several days, a white OCIA was sobtaled, € amount was far too small to admit of a malting point 8 134 APPENDIX. determination, or the application of other tests, in order to establish the identity of this compound with phytosterin or —— choles- terin-like principles. The fatty acids melted at 53— The powdered fruits were then exhausted with sia which dissolved out an alkaloid, having a slight numbing sensation on the tongue, and appearing to be cocaine, Absolute alcohol then removed cocatannie acid and an alkaloid ; and finally water extracted colouring and albuminous matters, and some- thing which reduced alkaline copper solution on boiling. The percentage composition of the fruit as deduced from the examination may be arranged as follows :— Moisture lost at 100° C. after partial desiccation over sulphuric acid... eas ses wee we w+ OECD Ash .. oe one SZ actun aka caine acne 3° 021 per uk of glycerides of fatty acids, and 1-519 per cent, of im- pure phytosterin (?) with colouring matter... ww. 4540 Ether extract, soluble in petroleum ether *232 per cent., soluble in water and containing cocaine °11 per cent,, soluble in absolute alcohol -069 per cent., soluble in ether but insoluble in petroleum ether, alcohol or water °029 per cent. 440 Absolute alcohol extract contaiiing eaataxtiis naa and a trace of alkaloid, we oe es wee SBZO Aqueous extract . « 23°440 (CG, 7 Ps & Warden, Phare m. ou, Fey: oth, 189).) RUTACEA, Oil of Lemon. V. Olivieri (Gazz, Chim., xvi., 318) found in oil of lemon, besides the limonene (Wallach), also another terpene C!°H"*, boiling at -170—170°5° C. (338—339° F.),the tetrabromide of which fuses at 31° C. (88°F.), but the dihydro-chloride showing the characteristics ‘oflimonene. From the higher boiling portions the author has fur- thermore isolated a sesquiterpene C'°H**, boiling at 240—242° ©, (464—468° F.), which increases in quantity with the age of — the oil. For detecting adulteration with turpentine, the author recommends use of the polarimeter, Lemon oil is levogyre APPENDIX. 1 85 (2)p = —55°, while oils of turpentine are more or less dextrogyre, French oil of turpentine is levogyre.) (Am. Journ, Pharm., Dec. 1891, Neroli oil. Pith order to be able to submit neroli oil to a closer examination, essrs, Schimmel obtained in the spring of last year, from the viera, a large quantity of the flowers of the bitter orange, The lossoms were consigned preserved in diluted sea-water, and were ived in good condition with the full odour of fresh flowers, ‘om the equivalent of 560 kilos of fresh flowers, there was obtained a process of cohobation (0-460 gram of pure neroli oil, which in Many respects differed from the best French distillates met with in ; It had a specific gravity of 0-887, and was optically Already at a Seusperatare: of + 11° C., it showed an he oil solidified to amass of the consistence of butter. The stearop- ene of neroli oil, like the stearoptene of rose oil, appears to be a raffin-like body ; it can be separated from the liquid portion of the by the addition of 90 per cent. alechol, in which it is difficultly ble, The specific gravity of eleven samples of commercial neroli 1 obtained from the best sources varied between 0°875 and 0-88 5° Of nine oils, one was optically active, whilst the rs were all dextr pears the rotation varying between + 0°52’ + 9°40’. Only one solidified at 0° C., the others remained id and did not om any separation of seontoptels upon the addi- of 90 per cent. alcohol. Thecause of these differences between essrs. Schimmel’s distillate and commercial samples is not expli- tble without further investigation. Jigle Marmelos. The extract from the flower, called in English Marmel water, and own in Sinhalese as “ Pinidiya,” is used by the natives as scent one ve occasions. It is also sometimes added in the preparation of, etmeats for flavouring them. During the flowering season, boys id men in the villages surrounding Colombo may be seen plucking > flowers and bringing them in baskets to the town for sale, wher ey are readily bought for distillation. An infusion of the ni stade is used as a cooling drink. (H. D. Lewis in “‘ Trop. dgric.,” Sept. > Pe 218.) 136 APPENDIX, SIMARUBE. Quassine. Oliveri and Denaro give the following mode of preparation of quassine (Giaz, Chim. Ital., No, XIV.): Infuse for six hours 10 kilo- grams of powdered quassia with 45 liters of boiling water, taking care to retain the heat. Decant the liquid and make a second infusion, Unite the liquors and evaporate to 10 liters, filter and precipitate with q,s. of tannin. Place this impure tannate of quas- sine upon a filter, wash carefully, dilute with water, treat with carbonate of lead, and dry in a water-bath. Treat the tannate of lead and quassine two or three times with boiling alcohol, and distil the united liquors. The residue deposits crystals of quassine mixed with resinous matter. Purify by repeated crystallizations in alcohol and water. Thirty kilograms of quassia give 10 grams of pure erystallized quassine. LEvaporations should be made slowly and alkaline reactions should be avoided. BURSERACEZ. Chemistry of Myrrh. Dr. Oscar KGhler publishes the results of a chemical examination of Myrrh from Sumali (Archiv., June 2, 1891, p. 291): Ash 2°79 per cent., portion soluble in water 57 to 59 per cent., consisting of a gum, C°H*°O*. The portion soluble in alcohol was a mixture of resins. The greater portion was an indifferent soft resin (C) soluble in ether, C?°H**0°, Two bibasic acid resins, one (A) C**H'*0*, and the other (B) C?°H*%20°. The essential oil 7 to 8 per cent. ; ‘the principal constituent corresponds to the formula C*°H**O. the formula for A resin be doubled, all three formule will contain 26 - atoms of carbon, and the resins differ in the amount. of oxygen they contain— Indifferent resin C = O0?*H*'0? (OH)?*. i oi Band > ey 9 ga Resin acid A pe CPE ee, 2) © mM - =} pS is) me Pu se) | MELIACEZ, Naregamiaalata. 7 semiaeeis: has been physiologically investigated by Dr, Stefan Schongut of Vienna, He used it in 24 cases, namely,one of dysentery Ty LD We Se een APPENDIX: 137 - oné of pleurisy, two of pneumonia, four of emphysema, five of bron- chitis, five of heart failure, and seven of tuberculosis of the lungs in 4 different stages, One to thee gratimes of the tincture were given daily in doses of 3/10 to 6/10 of a gramme. Dr. Sth@ngut found _ the tincture to act as an emetic in doses of 1 to 2 grammes, No styptic or other action on the digestive organs was observed, and no benefit was derived trom it in the case of dysentery, He says: application of the r remedy was confined to diseases of the air pas= ges, In such cases Naregamia has proved to be an excellent expectorant, and especially i in cases where, with a limited amount of Secretion in the bronchi, a disposition existed to extrenie coughing, mt where there was the presence of a tough and tenacious sputum ; Which embarrassed the elimination of this undesir able factor. In one ) od eens Pieciacape fonideus great service. In a nenepe of catarrh disappeared, thé rasping diminished materially, and though the quantity of the sputum at first increased, it finally Dr. Schoingut also states that the tincttre of Naregamia his” a oot beneficial aétion in cases of pulmonary emphysema, and 7 tit seertied to aid the expectoration in pneumonia during the eriod of re:sdlutién where the riles were ptominent and frequent. | the case of patients affected with dyspnea, he found that the reathing became less difficult under its influence, but the effects seemed to be duié to ani iticreased freedoni of expectoration and the In ion which agrees with the results of experiments on animals b. of. von oat showing that it has no direct action on the respira- tory cen No ca influence on the circulation has been observed under the influence of Naregamia, only a short and irregular increase of sure being noted after large doses reaching up to 5 grammes, Naregamia. does not exert any perceptible effect upon the digesé aa and no toxie properties } reside in the remedy. . 138 APPENDIX, SAPINDACEZ, Sapindus Honey. (Letter to the Honorary Secretary, Bombay Natural History Soctety.) I am sending you a box of dead bees I picked up under a tree now in flower in the gardens, Sapindus emarginatus. The tree begins to flower about the middle of October, and bears a profusion of small, whitish, inodorous blossoms which attract the bees. It seems very strange that insects possessing such a wonderful instinct should drink the nectar from the flower and get killed in this way, for I found them dead in thousands under the tree. The effect produced appears to be that of a powerful purgative, and there are now num- bers of bees buzzing about on the ground unable to fly, (Thos. H. Storey, Oodeypore, December, 1890.) The bees sent were Apis indica. It appears from this letter that the nectar in the flowers of the Soap-nut tree contains saponin, the active principle of the plant. The fact here recorded has not escaped the attention of the Hindus, as Sanskrit writers mention a plant or flower growing in Malwa which they call Bhramara-mari, Bhringamari, or Bhramarari, 7,¢., ‘‘ bee-killing,” Schleichera trijuga, Willd, The seed-oil of this tree, which is known in the Sunda Islands under the name ‘‘ Macassar oil,” and enjoys a great reputation as a hair dressing and means of removing scurf and eczema, has been submitted to examination by Messrs. Thiimmel and Kwasnic (Pharm. Zeit., May 20, p. 314). It was found that the seeds, which - contained no starch grains, yielded to petroleum ether 68 per cent. of fixed oil, but from the seeds freed from epidermis only 45:8 per cent. was obtained by pressure. The oil was in both cases of the consistence of butter, yellow, mild in taste, and with an odour of bitter almonds. It melted at 21° to 22° C., but after long standing the more solid glycerides separated, coating first at 28° and appear- ing under the microscope as fine needles. The fatty acids, with the exception of 3-14 per cent. of free oleic acid, were present as glyce~ rides. Of those in combination 70 per cent. consisted of oleic acid, and of the solid fatty acids 5 per cent. was palmitic acid and 25 per cent, arachic acid, the characteristic acid of the — Lauric : acid was not present, and of the volatile fat acids only acetic acid APPENDIX. . 139 - and no butyric acid could be detected, Hydrocyanic. acid was _ found in the oil and in the seeds, being determined as 0:03: per cent, _ in the former and 6-62 per cent. in the latter, No amygdalin could 4 be detected in the seeds, but hydrocyanic acid, benzaldehyde and a grape sugar, possibly the decomposition products of it, were found. _ A small quantity of cane-sugar was also separated in the crystallized form (Pharm, Journ,, May 30th, 1891). Saponin. _ The varying statements made by different authors in respect to. substances described in recent years under that name are identical ; nd, if so, by what empirical formula saponin would be best repre-. sented (Annalen, cclxi., 371), The first question he answers in th ffirmative, having arrived at the conclusion that pure. saponin from uillaia bark is identical with that obtained from various. caryophyl-. 2 CO? H0" +6 H*0=2 C#H"0? +6 0°H0*, Saponin,. Sapogenol. . 2 C?H"02745H?O= C*H*O? +5 C°H!20% Sapogenin. 2C?H"01' +5 H*O= 0*°H*O' +4 C°H"0°%, Saponetin. 2 C10!" + 4 H20=2 C?°H20" +4 0°H0°%. Saporetin.. (Pharm, Journ., May 2nd, 189%.) __R. Kobert considers that there are a series of saponins of the general formula C"™H*"*O"°, several of which are known, Saponins. ‘ent pl and show great Bittineatiing thei aaa action, The ae of the Agrostemma Githargo nh cockle), one of these substances, is absorbed both by 140 APPENDIX. subcutaneous tissues and by the testinal canal, and thus acts as 4 dangerous poison, It is recommended that, before using this seed as food, the shell and embryo should be separ ated. (Chem. Centr. 1891, ii., 176.) ANACARDIACEA, Mango Kernels. ‘Hindu doctors consider the kernels of the unripe Mango fruit to be very astringent, much more so than the kernels of the ripe fruits. Mohideen Sheriff and P, S. Mootoosawmy speak highly of the pow- dered kernels as a remedy for diarrhea in place of chalk powder, In times of searcity the boiled seeds have been used by the natives as a food. An analysis is here given of the kernels of unripe and ripe Mango fruits :-— ' Unripe. Ripe Fat... ise ete wag a | ee 14°75 Tanjin 24. as ove atts 8°97 8°45 Sugar and Gum ... i ens 4°90 6:00 Ash tee as = iv 1:98 2°32 Moisture .. es es we AO 11°28 Residue ne sve cha ie ee Ue 57°20 300-00 100-00. The residue consisted mostly of starch. The fat, after washing with alcohol, melted at 34° and became solid again at 3u°. (D.L.) Anacardie Acid as Hair Dye. The pigmentary properties of the viscous liquid secreted under. the pericarp of the cashew-nut (Anacardium occidentale) has long been known, and the liquid has been stated to yield a goyd indelible. stamping ink. According to Herr Gawalowski (Zeit. st Apot.-Ver., Sept. 10, p. 485), the ammonium salt of anacardic acid (C??H**0* a be one of the constituents of the liquid, can be advantageously used as a means of darkening the hair, For this purpose the hair is first moistened with an aqueous solution of the salt and afterwards combed — with a comb that has been dipped in a solution of ferrous sulphate, — or the ammonium anacardate may be applied in a pomade or oil, and — d of the solution of ferrous bag. 1 an oleate of iron may be — the hair eemyee | WEVA sic “Sicheonealn bd 2s: haa APPENDIX, 141 so treated assumes a more or less dark colour, which is tolerably persistent, but nothing is said as to the exact tint. Itis obvious that anacardic acid used for this purpose must be quite free from the eerid cardol that accompanies it in the nut. Herr Gawalowski directs ree piss Petne Ss en i with alcohol and decomposing the lead sk so obtained with ‘freshly prepared sulphide of ammonium and filtering. Upon strongly cooling ate, which contains the ammonium salt of anacardic acid and ammonium sulphide, and treating it with sulphuric acid, the Said separates at once as a soft mass, which after being pressed between filter paper is dissolved in ammonia and then remains soluble in water. According to Dymock (Veg. Mat, Med. W. Ind., p. 199), @ tar obtained in roasting thernuts, and largely used in bedi for _tarring wood, contains ahet 90 per cent. of anacardic acid and af per cent, of cardol, (Pharm. Journ., Oct. 8rd, 1891.) LEGUMINOSAS, A description of the preparation of Catechu or Cutch, The merchants of Nasik, Gangapur, and other towns engage the rvices of the Aétoris* for the purpose of manufacturing Catechu, bis usual with these merchants to descend into the Concan at the termination of the rains. They enter into an arrangement with i the return of the Katori to his old residence. The trader being joined by the Kétoris, the latter select a spot where the Khair trees leacia Catechu) are numerous, The merchant then begins to erect us xtensive shed, but as he has only one or two servants and three matchlock men with him, he employs the Katoris to build it, SF or HAH! the name of a jungle tribe in Western India, whose occupation is the collection of H[7 or Catechu. 142 APPENDIX. These sheds often cover one or two begahs of ground. In the-centre a temporary dwelling is built, in which the merchant resides and ’ lodges his supply of stores for the consumption of the Katoris and his own establishment, The following are generally the articles in store: Rice, ndchni, urid, onions, garlic, pepper, salt, turmeric, cocoanuts, cumin, asafcetida, salt-fish, ghi, oil, tobacco, steel, arrack, and various sorts of coarse cloths, These things are disposed of to the Katoris at from 50 to 75 per cent. above their value in the neighbouring markets, The Katoris erect their bhoongas or huts around the merchant’s shed,- and in front of their hut they prepare the ¢déroo or fire-place. They form the fire-place by digging a trench four or five cubits in length and one in breadth, which they cover at the top and leave the ends open to admit the air to pass freely through. In the top there are twelve small round holes to receive an equal number of pots, Before they commence the operation of cutting any billets of wood, they perform certain propitiatory rites, by worshipping one of the Khair trees. Having procured a cocoanut, some xed pigment, and a little frankincense, they select a tree for their purpose, rub the red pigment on the trunk near the root, burn the frankincense in front of it, and then break the nut; after which they join their hands in a supplicatory position, and address themselves to the tree, asking it to bless their undertaking, and to allow them to prepare abund- ance of good catechu. Having constituted the tree by this cere- mony, a subordinate deity, which they term Rén Sheo Wéria, they divide the consecrated cocoanut among those present. Each family possessing a fire-place performs a similar ceremony. They make one or two incisions in the trunk of the tree during these rites, but will not cut it down at the time, although these trees are sometimes cut down at a subsequent period, The following day the Katoris proceed into the jungle and examine the Khair trees, They, in the first instance, strike two or three blows with an axe deep into the trunk of a tree to obtain a chip from near the centre, and if, upon examination, it appears to have attained maturity, that is, if it is of a red colour (termed by them mérhi), and there appearsa white crust formed by the inspis- sated juice, they are satisfied the tree is a valuable one and they cut itdown, These people have a superstitious dread of bad luck attend~ ing their operations, and they object to a person speaking while a tree, APPENDIX. 143 which they are cutting, is in the act of falling. The branches, bark, and the white portion of the wood are cut away when the tree has been felled, and it is then taken home. The length varies from four to six feet, and as the wood is extremely hard, the ciit- _ ting of one billet is considered sufficient labour for the day, The next day, early in the morning, they cut these billets ito chips ; how= _ ever, they are careful not to eut more at one time than may be required for the boiling operations of the day, as they think the chips would be too dry on the second day. ‘To enable them more conveniently to cut these hard billets into chips, they drive three pieces of timber, each having forked branches, of different lengths, firmly into the ground about half a pace distant from each other, and the lowest being on a level with the earth. The billet is placed in a _ 8loping position in the forks, and lies quite secure to be cut. The _ chips are heaped near the fire-place, after which the men take their breakfast, and then proceed to the jungle. The labour attending the boiling process always devolves on the females: the Katori’s wife ot _ wives (for they sometimes have two of three), when she has finished her own breakfast, kindles the fire in the féroo, and then puts two handfuls of chips, neither more nor less, into ten of the pots, leaving the one at each end empty ; water is poured in until it rises four fingers’ breadth above the chips; this is ascertained by means of @ small stick marked like a scale, the lines being distant from each other a finger’s breadth, It has been mentioned that there are twelve holes in each fite-place to hold that number of pots, but should the persons composing the family be sickly or old, they will most likely only use six pots ; each _ of these pots will contain about three quarts of liquid, The pots at each end are only used during the sevond and third stages of the _ process. When the liquid has been well boiled and evaporated to a -finger’s breadth under the surface of the chips, they take the pots _ Successively off the fire, and pour the liquid into one of the empty ones ; after it has been well boiled in this, they apply the scale, and, if it is ready, they transfer it to the other empty pot. It is boiled down in this pot till it has attained what they consider the requisite degree of consistency, and then emptied into a trough made of the _ Pangara tree (Erythrina indica), as the timber is soft and readily sorbs water, The women now fill the pots with fresh chips, and the boiling process is thus continued until evening. 144 APPENDIX, Should the liquid in any of the pots, during the boiling process, take a longer time than usual to thicken, some of itis taken out and put into one of those pots in which the chips remain and which had just been strained, Whenever they find the liquid overflow the pot from excessive shales, they sprinkle a little bran on it to make it subside. When the men return home in the evening, each with his billet of wood, they examine the liquid deposited in the dul or trough, and, for the purpose of drying the substance and rendering it more adhesive; they use a piece of old kamli (country blanket), with which they keep stirring the liquid for two or three hours. They use the Kamli, as the kit (catechu) does not adhére to it, and it is left exposed during the night that it may cool and become firm. If after the usual time they find the &d¢ continties rather moist, and that it does not _ appear to possess 4 sufficiently adhesive quality, they bury it in the éarth for three or four days, after which it becomes dark and hard, but the people ahem eat kat of this description ; it is used by masons who mix it with lim By dawn in 7 morning the females aie at Work again; they take the kdt out of the troughs in masses, and place it in baskets, to permit any Femaining liquid to run off more freely, and at the expiration of three or four hours, they take the baskets to the merchant. Here théy divide it into small lumps abouit the size of a fig. They give ten of these lumps for a dhabbu (half aniia), They ‘vill sometimes mantfacturé a sufficient ‘oktity to allow of their disposing of the value of eight or ten dhabbus in one day. When the Kitoris deliver the fresh kat to the merchant, it is placed on the ground in the shade to dry, with a quantity of small chips previously scattered over the place, to prevent the earth adher- ing to the kit. It takes three or four days to harden; during this time, each of the little lumps is turned over once a day, and gently pressed with the hand to accelerate the drying process. The kat must always be dried in the shade, for if ede to the heat of the sun it would dissolve and turn black. The Kitoris are paid for the greater part in such iecessaries as they may be in want of, and whatever balance remains is credited by _ the merchant to liquidate the sum due to the village grain-dealers ‘giv 4 the Kitoris permission to quit their villages, — APPENDIX. 145 The Kitoris thus employed are not permitted to sell kat to other _ persons, and the merchant, to guard against any roguery on their _ part, has their huts searched daily, _ The heat in the monthsof April and May puts a stop tothe manu- facture, as the kt will not thicken and dry when the atmosphere is _ _ very warm 4 When the whole supply of kat has been dried by the merchant’s _ people, it is piled into long heaps or ridges, and previous to its being _ removed from the jungle to his own house, he deems it necessary to _ propitiate the goddess Bhavani. Accordingly, a coarse green sdrhi, a _ choli, some glass bangles, a small-toothed comb, and a string of beads _ are placed on one of the heaps of kat; then some turmeric, red pig- ment, a casket or small box and comb (ist weit), red lead, a _ cocoanut, and frankincense are placed near the sérhi, after which a _ sheep and fowl are sacrificed at the shrine. It is said that the merchant reckons that he receives about ten seers* of the kat for the rupee. (Mayor A, Mackintosh, Trans. Bom. Geograph. Soc,, i., p. 331, Cessalpinia Sappan. Schreder, in the Berichte der Deutschen Chemischen Gesellschaft, 1872, 512, and 1879, 596, has shown that Sappanin, the crys- talline colouring matter of Sappan-wood, is not identical with Alhagi camelorum. ~ Aitchison (Notes on Prod. of W, Afghanistan and N.-E, Persia, 8) says :—“ After all other shrubs and plants have dried up owing the autumnal hot winds, this still remains of a vivid green, and is eagerly sought for as fodder by camels, donkeys, and goats, During certain seasons, and in special districts, when its fruit is beginning to ripen, the whole shrub becomes covered with tears of glass-like beads, the largest the size of a pea; thisis the Manna eee on this shrub, called in these parts ¢ar-anjabin, which is very extensively collected, both for local consumption and exportation. eC * The full seer — rupees’ weight, 2 Ibs. 146 APPENDIX, The ground-nut oil trade in Pondicherry. The ground-nut oil trade of Pondicherry has increased enormously during the last few years: twenty years ago the total quantity exported amounted to only 1,403 casks, the whole of which was taken by Mauritius and Réunion; during the twelve months ending 3ist December 1890, the total shipment rose to 18,485 casks, 7,503 being consigned to Rangoon and Moulmein; large quantities were also taken by Calcutta, Coconada, Singapore, and Penang. The oil trade with Burmah, which scarcely .existed eight years ago, has now risen to a steady demand for about 700 candies a month. The oil is put up in English beer hogsheads holding 440 Ibs. each, and in Cochin oil casks containing 550 Ibs. each. The tabulated tables given below show the total shipments, and the highest, lowest, and average prices for certain given periods. The ground- nut kernels are crushed exclusively by the ancient wooden presses. of exactly the same pattern which have been used for several centuries ; about 1,200 of these mills are employed in crushing the kernels—800 at Vilvanur, a village in the Villapuram taluq, — eighteen miles west of Pondicherry, and 400 in Pondicherry and the neighbouring communes: the trade is entirely in the hands of native operators, who buy and crush the nuts, and ship and sell the oil without the intervention of any Recpenk agency. A company was started at Pondicherry a few years back for erecting and work- ing a hwilerte tobe worked by steam power, andin due time the mill commenced crushing, but the results were unfavourable, the cost of working and of the raw material being largely in excess of the value of the oil produced; after persevering for upwards of two years, company No, 1 decided to close up the concern by liquidation ; but for some time no purchaser could be found, and it was therefore resolved to sell off the property by public auction, but ‘ bidders,” were not forthcoming, and as a last expedient the factory en dloc was transferred to a small party composed of original shareholders, fora mere song. This company No. 2 soon came to grief, and finding the losses on working to be more than they cared to bear, mill was again closed and advertised for sale. After a con- siderable delay a Caleutta firm bought the property, and having made various improvements in the machinery, set vigorously to | t crushing, but with no better result than that obtained by es Nos, 1 and 2; and the factory was again closed for the APPENDIX. - : 147 ird time in about as many years, and company No. 3 retired. And now the end of Pondicherry kuilerte has come, and the machinery is being taken down and conveyed to Bangalore, where it is to be -erected and worked for crushing ground-nut kernels: Bangalore _ s already one steam oil mill, and it has to be seen whether two be made to pay. The complete failure of the several attempts ade to work the Pondicherry factory is attributed to various causes, of which the following-are the chief :—Firs?, the inefficiency of the machinery generally, and of the engine and boiler in parti- cular, which caused an extravagant consumption of fuel to obtain inimum results ; second, the absence of a practical engineer thoroughly acquainted with oil crushing machinery; third, the want f a sufficient working capital so as to purchase the raw material, fuel, &c., in advance, when prices were et and fourth, the want of asimity among the owners. The ae however, were 80 far e developed only about 1875, when 9, : eluding 1,581 to Bordeaux, 1,036 to Marseilles, 572 to London, 207 7 to Havre, and 200 to Martinique; but the trade with Europe pped when Marseilles began crushing ona large scale, and ng the last twelve years there have been no transactions, use of the oil for cuisine purposes is extending every year, ecially among all classes of Indians, and particularly with: an emigrants working in foreign countries. The 12,000 casks shi oped yearly to Burmah and Mauritius are consumed chiefly by dians, and it is likely that Natal and other places where Indian ur is employed will presently become large consumers. Ground- ut oil is not much used by Europeans, as the taste of the kernel is er strong, unless properly manipulated ; many native cooks, how- clarify it so thoroughly that it is rendered tasteless, and equal, b superior, to ordinary olive and salad oils, ‘The process is a simple one, but great care and aes are necessary to insure 148 APPENDIX. success : if the clarifying secret were better known, the oil would, no doubt, to a large extent, take the place of ghee; it is much better for cooking purposes, far cheaper, and more readily transported, while it cannot be easily adulterated. The consumption of the hutle @’arachides seems to follow on the track of Indian emigrants: in 1880 there were but very few Indians settled in Singapore, Penang, Xc., and in that year the export of ground-nut oil amounted to only 10 casks; in 1890 the shipments to these two ports amounted approxi- matively to 1,80) candies, The future of the export oil trade seems to wear a decidedly bright appearance, and there is no apparent reason why the development of the last few years should not continue at the same ratio for at least some years to come. The value of the traffic to Pondicherry is very great: besides the labour required to work the native mills, employment is given to a large number of coopers and others in preparing and shipping the casks. The following statement shows the total number of casks exported for the periods named below :— Number of casks 1835. 18386. 1887, 1838, 1889 1890. exported ..,... 10,403 10,255 17,727 16,098 19,365 18,485 It will be seen by the above that the shipments during the last four years have not materially changed; the period of 1889 was excep- tional, the ground-nut crop being metas large, and the prices generally low. The statement given below exhibits the highest, lowest, and average rates, per French candy of 529 lbs, English, during the several years mentioned :— 1875. 1880. 1885. 1890, ie 6 Ne... Re, a Rew a. Highest quotations per candy... 49 0 70 0 67 0 86 0 Lowest per candy we ies ae ee 2 ge © ae eee Average do. ao “90 5-289 8 bo 14 62-4 The exceptional ee prices for 1875 are accounted for by the un- _expected heavy crop of kernels, which was greatly in excess of the foreign demand, which caused the rates to rule low, and to offer unusually good advantages to local crushers. (Times.of India, March 3lst, 1891.) Ponprcnmrry, ath April 1893.—The number of casks exported ae Mics year the, pperchanes. for APPENDIX, sis 1 49 Upper Burma first commenced, The high price of kernels through- out the season was no doubt the main cause of the falling off, but it is noticeable that there was a considerable decrease in 1891, when both nuts and oil were comparatively cheap, The average number of casks shipped yearly from 1887 to 1890, both inclusive, was 18,068, as compared with 15,390 for 1891 and 1892. The average quota- tions of the oil, for the same periods, were Rs. 59 and Rs. 70, respectively, per Fr ench candy of 529 lbs. The trade with Caleutta, the Straits and Coast ports shows no signs of improvement, while Mauritius and Bourbon figures remain pretty much the same as in former years. The ground-nut oil trade—at least so far as its con- sumption is concernaed—is an enigma. In Bourbon and Penang, _ where Indians monopolise the labour markets, very little of this generally indispensable culinary article is used, while in both Upper . and Lower Burma the consumption is enormous, although the Indian population is, comparatively, very much less than it is in the’ former colonies, We must assume that the native Burmese is the better customer of the two. The price of the oil has risen in greater pro- portion than that of ground-nuts. In 1875 the highest quotation was Rs. 49 per candy and the lowest Rs. 32-12-0, when in 189 the rates were Rs. 86-8-(0 and Rs. 69, respectively. As in the case of the kernels—which are grown almost exclusively on British soil— the great bulk of the ground-nut oil shipped at Pondicherry is manufactured in English territory, the village of Valavanur, a station on the Pondicher ry-Villapuram Railway, supplying th greater part. The trade is — in the hands of native operators. The approximate value of last year’s shipments may be taken at 114 lakhs of rupees. For the current year the prospects are, so far, encouraging. In spite of the high prices of the kernels, the ship- ments from the 1st January to the 31st March amounted to 3,928 casks, as compared with an average of 3,888 casks for the same period uring the preceding four years. The ayerage price was Rs, 73,140 per candy, the highest Rs. 79-8-0, and the lowest Rs. 65-8-0, against Rs. 67-5-0, Rs. 83-8-0, and Rs. 58-12-0, respectively. (Madras Maii,) Se a SS seb Crotalaria paniculata. Dr. Mootoosawmy, in March 1890, sent a specimen of this plant for identification, It is used as a fish poison in Tanjore and other ‘places in Southern India, and is known by the Tamil name 150° APPENDIX, Valithe-pundu. An alcoholic extract of the plant had a ‘strong odour of henbane, and contained a soft resin, a tannin, and an alkaloid, the latter being the active principle. (D.H. Crotalaria retusa, Linn. Bot. Mag., t. 2561; Rheede, Hort. Mall. ix., t. 25. Greshoft (Med, wit, S’lands Plant, vii., p..31) has shown that the leaves of this common plant, the Bil-jhanjhan of Bengal, the Ghdgri of Bombay, and Potu-galli-gista of Southern India, contain a con- siderable quantity of zxdican ; and that the seeds contain an alkaloid which is a strong poison, and is probably closely related to the poison- ous alkaloids of Cytisus, Ulex, Spartium, and Lupinus. The same base was found in larger quantity in the seeds of C. striata, DC. Bot, Mag., t. 3200; Reich. Icon, Exot., t. 232. ‘Millettia atropurpurea, Bent, Wall. Pl. As. Rar., t. 78. Greshoff (Med. uit. S’lands Plant., vii., p. 33) has shown that the seeds contain a glucoside similar to, if not identical with, saponin, The plant is employed as a fish poison in the Dutch East Indies; it is also a native of Martaban, Tenasserim, Malacca, and Pénang. Pithecolobium bigeminum, Wart, According to Greshoff, the bark contains 0°8 per cent. of a non- volatile, amorphous alkaloid, which forms crystalline salts, and separates as a heavy, yellow oil on the addition of alkalies to solu- tions of the latter, With 1C0 parts of water, it forms a turbid liquid, which on warming assumes the appearance of milk, but becomes clear on the addition of an acid. The solutions have a burning taste, and give the usual alkaloid reactions, It has a strong corrosive action on the skin, and is fatal to fish in a dilution of 1: 400,000, The same compound appears also to occur in P. Saman, Benth. (Meded. uit S'lands Plant., vii., p, 38.) Derris elliptica, Benth. Wight, Ic. t. 420. The roots of this handsome climbing shrub, according to the Kew Report of 1877, afford a useful insecticide for agricultural are also used to kill fish. The Malays are said to use he ba ie a8 one of the ingredients of their arrow poison, : APPENDIX. 151 According to Greshoff (Meded, uit. S’lands Plant., vii., p. 12) it has a powerfully poisonous action on fish, a decoction of the roots being fatal even when diluted with 300,000 parts of water. The only active constituent isolated is a resinous substance termed derrid, which does not contain nitrogen, and is not a glucoside; it readily dissolves in alcohol, ether, chloroform, and amyl alcohol, but is very spar- ingly soluble in water and potash solution. On fusion with potash, it yields salicylic and protocatechuic acids. It occurs almost entirely _ inthe cortex of the root, but has not yet been obtained pure. Its alcoholic solution has a slightly acid reaction, and a sharp aromatic : , causing a partial insensibility of the tongue, which remains foe hours. A solution of 1 part in 5 millions is almost instantly . [to fish. A very similar compound is found in the seeds of Peharhenss angulatus, Rich., a decoction of which is quickly fatal in a dilution of 1:125,000. Itis probably identical with derrid, but until this has been experimentally proved it may be distin nguished as Pachyrhisid, It is very readily prepared from Pachyrhizus, which occurs.in all tropical countries, as the tannin compounds, usually so difficult to separate, are not found in this plant. The seeds also _ eontain a non-poisonous, crystalline compound, which is 7 soluble in alcohol, and has at 39° the consistence of butter. Sophora tomentosa, Linn, The plant formerly renowned as a medicine (“ Antichéloniais Rum- phi ”) contains a poisonous alkaloid, soluble in ether, which is contained in largest quantity in the seeds. A small quantity of this ‘substance, received by Professor Plugge as a thick red-brown fluid, when tested physiologically, gave results indicating the pega that it is identical with cytisine, the alkaloid of laburnum seeds, and P antity 0: ‘material available (Archiv. d. Pharm., ecxxix., 561). Alkaloids have previously been found in S, speciosa and S. angustifolia, but have not been closely investigated. Abrin. _ P. Ehrlich (Deutsche Med. Wohkenschrifi, 1891, No. 14) com- pares the toxic properties of Abrin with those of Ricin. Injected ‘hypodermically, he finds abrin (Merck’s) to be et half as poisonous ricin ; taken internally, it is still less active. bee APPENDIX, Subcutaneous injections in mice seldom produce the necrosis so com- monly observed when ricin is injected, butinvariably cause epilation at the seat of the injection. On the other hand, the action of abrin upon the conjunctiva is much more powerful than that of ricin. Ehrlich has succeeded in producing an immunity to the action of abrin similar to that obtained with ricin (ef Vol. III., p. 305), Animals thus rendered refractory present a general and local immunity to the action of the poison ; they bear without injury doses four times as large as those which would prove fatal to an unprotected animal, whether administered internally or injected beneath the skin. Abso- lute immunity of the conjunctiva to the action of abrin may be obtained by its internal administration for several weeks. From these facts the author concludes that a substance, whieh he calls anti-abrin, is developed in the blood which completely counteracts the action of the poison. Immunity to the action of abrin affords no protection against the action of ricin, nor does the administration of ricin lessen the ac- tivity of abrin; a rabbit whose conjunctiva had been rendered insus- ceptible to the application of solid ricin suffered from an intense pine Scapa when a solution of 1:10000 of abrin was applied to the part. ROSACEA. Otto of Roses. The results of the investigations on Rose Oil, which have been carried on for a long time in the Pharmaceutical Institute of Breslau University, have been published by U. Eckart ( Archiv. der Pharmacie, 229 [1891], 355). A body C°f?*O, which is called “ Rhodinol,” forms the chief constituent of both German and Turkish otto; it boils at 216°—217°, and shows all the reactions of an alcohol. With acetic or benzoic anhydride it forms esters, which, however, during distillation, dissociate again into their constituents. By treat- - ment with halogen hydro-acids, Rhodinol chloride C'°H"’Cl, Rho- dinol iodide CuH"I, and so on, are obtained. Oxidation with potas- sium bichromate and sulphuric acid converts Rhodinol into an alde- hyde, which the author calls “ Rhodinal” and which is believed to be identical with Citral. By phosphoric anhydride Rhodinal is trans- formed in Dipentene in abstracting a pcs of water. i von ete eb: 1891.) _ eet paw 4 APPENDIX. 153 COMBRETACEA. Myrobalans. : — G. Zoelfell (Arch. der Pharm., 1891, 123—160) states that the tannin of myrobalans is a mixture of two tannins, one of which is the glucoside of gallic acid, yielding upon hydrolysis gallic acid and sugar (dextrose); the other tannin present is a tannic acid proper of the formula C!°H"°0, which at 100° ©. loses two molecules of water. The anhydrous acid 0'*H°O% is called ellagic acid (the formula of which is generally given as C*H80°) ; the hydrated acid C’°H"**0"° is called ellaggenic acid; the latter forms a penta- acetyl derivative, indicating five and four hydroxyl groups, respec- _ tively, in the acids. The tannins were separated by fractional . precipitation with lead acetate, subsequently purified by precipitation _ with sodium chloride and solution in acetic ether. Terminalia chebula. _ -My. A. Campbell Stark submitted a paper on the “Preliminary _ Proximate Analysis of a sample of commercial Myrobalans” to the _ Pharmaceutical Conference, August, 1892. __ A finely powdered and well-mixed sample yielded 7-05 per cent. __ of moisture and 2:3 per cent. of ash— Free fatty acid oes 2 1482 Petroleum Ether Extract ... { aerate) es 2 ies (Gallic acid .,. ioe t me oes yj Tannin vor ae: TBO “\ Green resin ... ge Oe Ethereal Extract ... (Brown resin ... foe ee Tannin wil ... 18°80 Alcoholic Extract ... es ; Bitter prineiple a ke i Glucose lad cae ED Saccharose ine ae Phlobaphane... Pa as = a = Pale green substance... ‘71 Aqueous Extract Sua cae or ves shen OAD The soft green resin found in the ethereal extract is presumably the ‘Myrobalamine” of Dr. Apery. The tannin was estimated in the aqueous solution of the alcoholic extract by means of copper acetate, 2 154 APPENDIX. including that also found in the ether extract: it amounted to 20°6 per cent., a lower percentage than that quoted by other investigators, who give the average of tannin in myrobalan from 20 to 40 per eent. Terminalia belerica, Rox. We have made the following experiments with the seeds of the large-fruited variety of this tree (see Vol, II., p. 5, e¢ seg.) :—9°5 grams of the kernels, equal to 22 in number, pulped with raw meat were eaten by a fasting cat at 11-40 a.m. At 2°30 p.m, the animal vomited several times, ejecting a number of worms and some fluid, but no.meat, 4 P.M. vomited bile-stained, frothy fluid, looks some- what distressed. No other symptoms were noticed, and on the following morning the cat was in its normal state, Our experiments thus appear to indicate the absence of any narcotic principle, but a substance which possesses emetic properties is probably present. MYRTACEZ, Clove Culture in Zanzibar.* Zanzibar is noted for being the principal source of the world’s supply of cloves, anda report on the cultivation of this article of domestic economy may prove of interest, en speaking of Zanzibar, we include the islands of Zanzibar and Pemba, three-fourths of the entire crop of cloves being produced in Pemba. Those grown on the island of Zanzibar are reekoned of superior quality and command the “better price, but this is probably due to the fact that the owners reside here, and can thus give their affairs the benefit of direct supervision. Certainly the conditions for their successful cultivation are most favourable at Pemba, where the rainfall exceeds that of Zanzibar, but the management. being left to careless overseers, the result is the eloves are imperfectly cured and (but little care being observed in handling) are frequently marketed in an inferior condition. The clove tree was first introduced into this country by the then Sultan, Seyed Said bin Sultan, about the year 1830, since which time its cultivation has gradually extended, until it is now the chief industry of the islands, of (YP : 7 ee” me t of Consul Pratt. Reprinted from the Gil, Paint, and Drug APPENDIX. 155 The industry received a check in 1872, the date of the great hurricane. At least nine-tenths of the trees were destroyed at that . time, so the larger part of those now standing are of new growth. : _ A peculiarity of the clove tree is that every part is aromatic, but _ the greatest strength is found in the bud, which is the “clove” of commerce. The finest quality of cloves are dark brown in colour, _ with full, perfect heads, free from moisture. ye - about 3 feet in height. They are then transplanted, being set about 80 feet apart, and are kept watered till they become well rooted. _ From this time on the young trees require only ordinary care, though the best results are obtained when the, ground about the trees is well _ worked over and kept free from weeds. The growth of the tree is very slow, and five or six years are required for it to come into bearing, at which time it is about the size of an ordinary pear-tree, and is usually very shapely. It is a pretty sight to see a young plantation just coming into bearing. The leaves, of various shades of green tinged with red, serve to set off the clusters of dull-red clove buds. Assoon as the buds are fully formed and assume this reddish colour, the harvesting commences, and is prosecuted for fully six months at intervals, since the buds do not form simultaneously, but at odd times throughout the whole period. The limbs of the tree being very brittle, a peculiar four-sided ladder is brought into requisition, and the harvesting proceeds apace. As fast as collected, the buds are spread out in the sun, until they when they are put in the storehouse and ‘assume a brownish colour, are ready for market. _ A ten-year-old plantation should produce an average of 20 pounds of cloves to a tree. Trees of twenty years frequently produce ‘upwards of 100 pounds each. _ The present season, commencing with July, able, and the crop will exceed that of any previous season, It will, ‘in all probability, amount to 13,000,000 pounds, averaging a local alue of 10 cents per pound, : 1889, is very favour- 156 APPENDIX. The Sultan derives no inconsiderable portion of his revenue from this source, since the duty is levied at 30 per cent. ad valorem, thus placing tothe Sultan’s. credit for the — year nearly, if not quite, $400,000. Besides the clove buds, the stems are also gathered, and form an article of commerce, commanding about one-fifth of the price of cloves and having about the same percentage of strength. To this circumstance is due the fact that ground clove can frequently be purchased in the market at a lower price than whole cloves. For the past fifteen years the cultivation of cloves has been the chief occupation of the Arab planters, and has always netted good returns. It seems probable that it will continue to be a profitable crop, since the consumption of the article appears to keep pace with the inevitable increase of production. Up to the present time the plantations have been worked with slave labour at comparatively small expense; but with stoppage of slave supplies from the mainland, great difficulty will be experienced by the planters during harvest time. One result will be an increase in expenses; but what the planters have most to fear is that the curtailment of the labour-supply will entail a direct loss by rendering it impossible to harvest the crop until after it has blossomed, when it would be unfit for the uses of commerce. Oil of Cloves. The value of this oil depending upon the quantity of eugenol present, H. Thoms proposes the following method of assay, depend- ing upon the formation of benzoyl-eugenol (see Am. Jour. Pharm., 1891, 406): 5 gms. of the oil, 20 gms. solution of sodium hydrate (15 per cent.), and 6 gms. benzoyl chloride are placed in a tared beaker of 150 cc. capacity and thoroughly mixed, this causing the mixture to become quite hot; after cooling 50 ec, water are added and heat applied until the crystalline mass melts, and again allowed to become cold; the clear liquid is run through a weighed filter (dried at 101°C.), and the same operation of washing the crystals repeated twice with 50 ec. water. ‘To remove the sesqui-terpene, which may contaminate the benzoyl-eugenol, the crystals have to be washed with alcohol ; this is effected by adding to the still moist crystalline mass in the. oaks 25 ce, alcohol of 90 per cent., warming until netic ie eg the solution until the crystals ae to APPENDIX. 147 separate again, then allowing the contents of the beaker to cool to 7 C.; transferring to the weighed filter and washing with a little 90 per cent. alcohol until the filtrate measures 25 cc. ; the filter with contents is then at once transferred to the beaker, dried at 101° C, and weighed. To the weight of the benzoyl-eugenol must be added 0°550 gm., the amount soluble in 25 cc. 90 per cent, alcohol; this weight multiplied by 164 (th lecul ight of eug d divided by 268 (the molecular weight of benzoyl-eugenol) gives the amount of eugenol in 5 gms, oil; for the percentage multiply again by twenty. An examination of sixteen samples showed the eugenol to vary from 76°87 per cent, to 90°64 per cent,; the oil distilled from the steins was found (contrary to expectations) to contain a high percent- age of eugenol, 83—85 per cent.; the specific gravity of the oil was not found to agree with the percentage of eugenol as the following — _ show: 1:059=83°2 per cent.; 1065=80°89 per cent.; 1-065=82°77 e (Pharm, Centralhalle, 1891, 589, Am. Journ, Pharm., Jan,, 1892.) =] 8 — 2 PASSIFLOREZ, Carpaine, the alkaloid in the leaves of Carica Papaya. A new alkaloid has recently been detected in papaw leaves. by _ M. Greshoff, of the Chemico-Pharmacological Laboratory at Buiten- zorg in Java. It was obtained by digesting the powdered leaves in with ether, and carbonate of soda was added until an alkaline reaction was evident. The precipitate thus obtained was readily soluble in ether, and on evaporation of the ether the “ carpaine” was obtaine in colourless rosettes of crystals to the extent of about 0-25 per cent. of the leaves employed. Although the freshly pecipitated alkaloid is readily soluble in ether, when once crystallized it redissolves but slowly, so that the crystals can be purified and rendered perfectly white by washing with a little ether, but the percentage obtained is ms reduced to 0-15 per cent, On a large scale the lime and 158 __ APPEND:X. petroleum method gives very good results, about 0°19 per cent., and would probably be preferred on the score of expense. Comparative experiments made on the young and old leaves freed from the ‘stalks — show that the old leaves afford when dried 0-072 per cent. of the alkaloid, the young leaves 0°25 per cent., and that on an average a papaw plant can be calculated to afford 30 grams of the alkaloid per year from the leaves. The hydrochlorate of carpaine, which contains about 82 per cent, of the pure alkaloid, is freely soluble in water. As yet comparatively little is known of the physiological action of the alkaloid, It appears, however, to act more especially upon the heart, Slowing its action, The lethal dose for a fowl of 500 grams weight was found to be about 200 milligrams. In a fowl of 350 grams weight no poisonous symptoms were produced with 50 milligrams of the alkaloid ; with 100 milligrams symptoms of poisoning occurred in ten minutes after injection into the breast muscles, but after twenty- five minutes the animal recovered its normal condition. The bird lay on its side and breathed deeply in a jerky manner, and showed slight convulsive movement of the whole body, but no irritability was noticed. Further observations are necessary to determine the usefulness or otherwise of the alkaloid in medicine ; should it prove unlimited quantity and in a definite crystalline condition. The alkaloid is easily precipitated from its solutions by the alkaloid reagents, The most delicate reaction is with Mayer’s reagent, iodoiodide of potassium, which in a solution of 1 in 300,000 gives a turbidity, and in 80,000 parts an evident precipitate ; phosphomolyb- date of ammonium has its limit of reaction at 1 in 75,000 parts, pieric acid at 1 in 30,000, and chloride of gold at 1 in 25,000. The alkaloid has a bitter taste, which is perceptible even in a solu- tion of 1 part in 100,000. CUCURBITACE. Constituents of Melon Seeds. C. Forti (Chem. Cenir., 1890, ii., 581) found these seeds to contain cholesterin and a dextro-rotatory carbo-hydrate apparently belong- ing to the galactan group. The oil yielded by the seeds to ether amounts to 49 per cent,, and is almost free from fatty acids, It contains lecithin. The phosphorus "asi 0:02 gers cent, (Year- Book of Phar m, 16h p- 194.) : APPENDIX. ~ 159 UMBELLIFERZ. Anethum. (Peucedanum graveolens, Benth.) “distillate from Indian dill seed is reported to have shown a difference in the aroma, a considerable variation in chemi- mposition from oil distilled from German seed.. From the om Indian seed there was a remarkable separation of a t heavier than water, the nature of which has not yet been The specific gravity reached 0-970, and the optical, -41° 30’, German dill oil consists of limonene and carvol am average specific gravity of 0-910, (Ber, von Schimmel 891.) Dorema Ammoniacum. 1 e of 4.2 (bury) we have received from Afghanistan lant. Anisun. ARALIACEA, — Fe Panax Ginseng. . arm. Leitschr. f. Russil., 1899, a 9%, 113, 130) cons m * s . es dryness. filtered, and the alcohol recovered. Panaquilon remains : light or mass, easily soluble in alcohol and d does not contain nitrogen. Concen- capiven a blood-red colour, gradually turning to anaquilon is neither an alkaloid nor a glucoside. aia acid a crystalline powder, panacon, e in water and ether, but soluble in alcohol, aii dissolves and colours it purplish red. 160 APPENDIX, e Concentrated nitric acid oxidizes it to oxalic acid. Garrigues gives the following formule: Panaquilon C?* H?°O**, Panacon C??H**0° (O=8). (dm. Journ. Pharm., July, 1890.) RUBIACEA, ‘ Randia dumetorum. Sir J. Sawyer (Lancet, Mar, 21, 1891) has employed a tincture of the fruit made with spiritus etheris, B. P., as a nervine calmative and antispasmodic ; the dose is“from 16 to 30 minims in water, but the strength is not stated. We have already shown that the drug contains saponin*and valeric acid. Ixora parviflora. P. 8S. Mootoosawmy has sent us a sample of the bark of this tree, with the remark that it is used in native medicine, mixed with a decoction of ginger, for anemic diseases; he suspected the presence of iron init. The bark contained a little fatty matter, tannin, red colouring matter and 11°5 per cent, of ash consisting of the usual constituents, with only a trace of ferric oxide. The decoction of the bark was of a deep red colour, which probably suggested its medicinal employment. Note on Catechu. In the Library of the Botanic Garden at Oxford I recently came across a book which apparently escaped the observation of the indefatigable authors of Pharmacographia, entitled ‘‘ Ehrenfridi Hagendornii Medicine D. et Pract. Gorl. Tractatus Physico- Medicus de Catechu sive Terra Japonica in vulgus, sic dicta ad normam Academiz Nature-Curiosorum. Jenx, 1679.” This gives very interesting particulars respecting the history, nomenclature, and physical characters of Catechu. “De patria Catechu.” The author writes:—‘ Si Catechu agno- men respicias, quod Japonica etiam indigitetur, facilis esset decisio, quem agnoseat locum natalem. In ambiguo tamen usque est, an in Japonica vel preparetur vel aliunde ad J aponenses transporteter, Ex aliis finitimis locis in Malaccam et Sinam exportari.” The italics are mine, _ “De differentiis Catechu,” ‘ Duplicis generis quod sciam, in- - — Sepa Restores. Una magisque communis Catechu species APPENDIX. 161 4 apparuit rubicundior, ad nigredinem veluti quandam inclinans, cum _ striis albicantibus, instar linearum per totum Catechu subjectum _ excurrentibus, itemque ponderosior compacturque. Altera a me visa _ fuit compacta, nec ita colorata, colore potius ad albedinem inclinante, porosior item, levioris ponderis, digitis quoque frangi _— terrique _ Ssustinens, nec Rae rubicundioris, ceu altera, adeo ferax ___ Other differences are noted. Whether the pale meres alluded to be the cutch of North India I am unable to say. May it not be the Gambier cutch? If so, this will be a very early notice of that drug, In another chapter of ‘‘ De Electione Catechu” the writer says :— “ Dsus obtinuit, ut si de notis bonitatis indijudicandis medicinalibus rubedine, que compactior, que ponderosior, quaque minus participat de lapillis, seminibus, lignis aliisque inibi interdum repiriri solitis. Qui fini etiam apud aromatarios jam receptum est, ut integros techu globos prius malleo contundant, visuri, quenam sit species, ne pallidiore et viliore ob metum adulterationis, qua Japonenses ut plurimum malé audiunt, emptores defraudent. “Sec. 2. Notaritamen expedit, suggerente id qualicunque experi- precipitandi et absorbendi, humores vitosos intentio est, modo prius probe 4 lapillis et depuretur.’ = 3 is devoted to the ‘Pharmaceutica’ ; section 4 to ‘ Thera- tic One prescription may be quoted, for it gives an example of the early use of the word chocolat— B/ Conserv. rosar-antiq. 54 ae ye es Flor borrag é . 38s Chocolat si ov eet Catechu “ sh ” 3) Vin. Malvat. q.s. cum ,°, cinnam, rosar. 4, g. j. M. sic viro eawem primario in eructatione ventriculi, qua premodum con- (By G. Claridge Druce, Pharm. Journ., Jan. 1892.) 162 APPENDIX, VALERIANEA. Valeriana Wallichii. Aitchison (Notes on Prod. of W. Afghanistan and N.-E. Persia, p. 96) states that gur-bdlchorak is a trade name for the roots of this plant in Afghanistan, He remarks :—‘“ A Kabul trader at Leh told me that it was the same as gur-alchorak in the Peshawur trade, and owing to a load of which he was once nearly driven mad in conveying it from Kabul to Peshawur, by all the cats in the country surrounding him at night, wherever he halted.” Aitchison supposes the name to be a st of Gurba-bélchorak, which would signify “the cat valerian. COMPOSIT A. Solidago Virga-aurea. Dr. Mascarel is said (Za France Médicale, Oct, 8, 1889) to have used the plant very successfully in cases of dropsy. It has long been used by country practitioners to produce diaphoresis. It grows plentifally in the Northern parts of the United States, and resembles Sol-odora, the “* sweet-scented golden rod,” or “ blue-mountain tea.” In administering it for cardiac dropsy, Dr. Mascarel reduces the dried plant—stems, leaves and flowers—to a coarse powder, and gives it in doses of one tablespoonful, beaten with an entire egg (yolk and white). He gives but one dose on the first day; but on each of the following days he adds a tablespoonful, until seven or eight doses are being taken during the twenty-four hours. The diuresis is said to continue until edema permanently disappears. Helenin in Tuberculosis. Helenin has now for some time been before the medical public as 4 remedy in phthisis, but without any apparent progress in its use. Dr, T. J. Bokenham has published an account of numerous experi- ments made by him as to the real value of the substance, and so far as can be gathered from the account given in the British Medical Journal (Oct. 17, p. 838) it would appear that the crystalline bodies oceurring in Inula Helenium are difficult to separate on a large or commercial scale, and that consequently alantic anhydride was the only substance procurable commercially for his experiments. The other crystallized bodies were, however, obtained in sufficient APPENDIX, 163 quantity for laboratory experiments. These experiments showed that any of the crystalline bodies would prevent the growth of the tubercle bacillus if present in the proportion of 1 in 10,000, and in any ordinary cultivating medium for this bacillus. The effect of the administration of the alantic anhydride appeared to be to pro- long life fora time in the animals experimented on, but not to prevent a fatal result, Helenin has also been lately given with good results in leucorrhea in the dose of 2-4 centigrammes (tép. de _ Pharm,, Oct., p, 481). (Pharm, Journ,, Oct, 31, 1891 Pluchea lanceolata. Description.—8hrubby, hoary pubescent, with sessile, very coria- length, having strong very oblique nerves on both surfaces. When dry, the leaves are of a pale yellowish-green. Heads of flowers in compound corymbs about the size of Groundsel, purple, involucre : bracts contracted atthe mouth, outer bracts obtuse, hoary, The g has no marked taste. Chemical composition.—The taste of these leaves is saltish and aromatic, They yield, in an air-dried state, 16°93 per cent. of mineral matter, consisting largely of alkaline ‘chlorides, the cubical alkaloi Pluchea hie, and conclude that, weight for weight, they are much weaker than senna leaves in their cathartic action. The Existence of a Mydriatic Alkaloid in Lettuce. The attention of the author was drawn a few months ago to the mydriatic action of an extract prepared at Hitchin from common lettuce, Lactuca sativa, when in flower. On examination, the myd- Yiatie action was found to be due to an alkaloid. The extract _ closely resembled belladonna extract in appearance, smell, and taste ; but a dose of 5 grains had been taken without injurious effects, | other commercial extracts of lettuce were, examined—namely, an extract of wild lettuce, Zactuca virosa, prepared according to the directions of the British Pharmacop wia, the history of which was unknown, and extracts of both the wild and the cultivated lettuce 164 APPENDIX. prepared at Market Deeping, in Lincolnshire, An extract of that variety of the cultivated plant known as Cos Iecttuce was also examined. They all contained an alkaloid which had a very marked power of dilating the pupil of the eye. Finally, a dried specimen of wild lettuce, collected when in flower, was examined. It contained a mydriatic alkaloid. The impure alkaloid obtained from the extract was a light brown syrup, which possessed powerful mydriatic properties. In order to purify it, it was converted into the oxalate. The alkaloid recovered from the pure oxalate, when crystallized from chloroform, closely resembled hyoscyamine, both in appearance and in melting point. The aurochloride was then produced by the usual methods, and this, after recrystallization, was obtained in the shining flat needles characteristic of the aurochloride of hyoscyamine. The estimation of the gold and the base in this compound showed that the alkaloid was one of three isomeric mydriatic alkaloids, having the formula C'H?*NO®%, while its melting point was 159-75° (corr.), and closely corresponded with that ascribed by Ladenburg to the aurochloride of hyoscyamine. The plant does not appear to contain a second mydriatic alkaloid, although it must be remembered that only small quantities of material were operated upon. _ The author has just shown that both wild and cultivated varieties of lettuce, especially when the flowering stage is reached, contain hyoscyamine, the mydriatic alkaloid oceurring in Hyoscyamus niger, Atropa Belladonna, and other plants belonging to the natural order Solanaceae, and it is probable that to the presence of this alkaloid the sedative and anodyne properties of extract of lettuce are due. That this important constituent has been until now overlooked is probably due to the fact that in chemical investigations upon lettuce the dried milk sap, lactucarium, has alone been examined, although its value as a sedative and anodyne is by no means established. The author found that lactucarium of both English and German manu- facture-was devoid of mydriatic properties and contained no alkaloi whatever. The fact that lettuce contains a poiso nous alkaloid is not of great importance in connection with its use as a vegetable, since it is only used for this purpose in the early stages of its growth, before the bitter milk has been produced, when the hyoscya mine is only present, if at all, in ein quantities. The amount of mydriatic alkaloid in eS Ee OTe eee Se ee ee APPENDIX. 165 the extract prepared from garden lettuce when in flower is not more 0°02 per cent. Nevertheless, cases have been recorded in which the immoderate consumption of lettuce has led to unpleasant and even fatal results. Lettuce belongs to the natural order Composite, This is the first occasion on which hyoscyamine has been found in plants not belonging to the natural order Solanaceae. (By T. 8S. Dymond, from the Research Laboratory of the Pharmaceutical Society of Great Britain.) Tagetes orecta. The flowers contain a crystallizable substance quercetagetin, having the composition C?"H**O** + 4H’0; it is the yellow colouring matter; its reactions in alcoholic solution are the same as those of quercetin, but it differs from the latter in crystalline form and solubility in aleohol. (Bull, Soc, Chim, [27] xxviii., 337.) Saussurea Lappa. Schimmel & Co, in their Report (April, 1892) state that Kusht root yields one per cent. of alight yellow essential oil, which possesses a sp. gr. of 0°982, and a rotatory power of + 15°20’ in a tube of 100 mm. It begins to boil at 275°, and about one-half goes over below 315°; then complete decomposition takes place, producing avery disagreeably-smelling vapour, When treated with soda, a part of the oil combines with it, and can be separated by acids. The root has a violet odour, but it does not seem to yield an odorous oil of that perfume. Messrs. Schimmel state that the odour of the oil resembles at first that of elecampane. After the volatilization of this odour, in about 24 hours, the violet odour develops, but not sufficiently strong to indicate that the oil could be of practical use, Mr, McDonell, Conservator of Forests in Kashmir, reports that the plant grows as high as 9,000 to 10,000 feet. The dried root . sells at Rs.25 per maund. It is collected by villagers and paid for at Tehsils. The chief purchaser is a Bombay Chinaman CAMPANULACEA, Lobeline. The only active principle of Lobelia inflata has recently been investi- gated by Dr, H. Dresser. Warm-blooded animals poisoned by means of lobeline succumb to respiratory paralysis, so it is to be included among the respiratory 166 APPENDIX. poisons. In dogs the physiological action of lobeline is first manifest- ed by a paralysis of the voluntary movements and by a concomitant exaggeration of the reflexes. Later these effects are complicated by aparalysis of the motor nerves, analogous to that produced by curare, Through its paralyzing action on the cardiac branch of the pneumo- gastric, lobeline resembles in its action the nicotine group. In warm- blooded animals the influence of lobeline is found in a great exalta- tion of the respiratory activity, It produces an acceleration of the respiratory movement, which is more persistent when the pneumo- gastric nerves are intact than when they have been divided. Further, the amplitude of the respiratory movements is increased, and the power of the respiratory muscles appears to be also augmented, Under the influence of comparatively small doses of lobeline, the in- hibitory influence of the pneumogastric on the heart, as well as its action on the ‘bronchial muscles, is suppressed. The respiratory muscles appear to receive especial stimulation from the respiratory centre when the latter is under the influence of lobeline ; as a result, the work accomplished by the heart and respiratory muscles is great- ly augmented. In comparison with the other agents which stimulate the respiratory functions, lobeline possesses the advantage over hydro- eyanic acid in its freedom from depressing action, while it surpasses ee in id i therefore — epeauees that the ‘employment o anti-asthmatic d by experi- mental facts, ite the author has not tiie any clinical experi- ments and offers no suggestions as to the proper form of employment of this alkaloid, (Archiv, fir Pes Pathologie und Pharma- cologie, 26 Band, Heft 3 und 4 H. Paschkis and A. Smita (Akademie d, Wissen., Wien, April 17) 1890, through Chem, Zeit., 1890, 594) use the following method for preparing lobeline: The herb of Lobelia inflata is extracted with water, acidified with acetic acid, the extract partly evaporated, made alkaline and extracted with ether. An extract was taken up with water and being acid was made alkaline and shaken with ether. The ether was evaporated and the alkaloid obtained as athick oil of a yellow colour. For purifying, the alkaloid was dissolved in ether, shaken with water acidulated with hydrochloric acid, then made alkaline and taken up with ether. This was repeated three times, the genes solution then dried with potassium hydrate, and the ether d in an atmosphere of hydrogen, The free alkaloid APPENDIX. 167 o be benzoic acid. (Am. Journ, Pharm., July, 1890.) PRIMULACEZ. Anagallis arvensis. A. Pehtoagas (Journ. Pharm, von Els. Lothr., 1891, 171) has from this plant two glucosides identical with those obtain- quillaia and senega, The plant is said to be used in Mexico bstitute for soapwort. SAPOTACEZ, Indian Gutta-percha. atural sources of supply of gutta-percha, and the possibility of exhaustion, were referred to in the Kew Reports, 1876 (p. 23); (pp. 30, 31); and 1881 (pp. 38-45), A few trees, natives of the n peninsula, yield sabstances more or less similar to gutta-percha, of these is Dichopsis elliptica, Dalz. (= Bassia elliptica, Isonandra "he following note on this plant appeared in the Report of the Royal Kew, 1881, p. 44 :— This tree appears to be common on the Malabar Coast, the forests , the Wynaad, Travancore, &c. It grows toa height of 80 or A substance similar to the gutta-percha of commerce is d by tapping, but the tree requires an interval of rest of some , or even of days, after frequent incision. In five or six ea lon the increase of heat. It is not found applicable to all for which gutta-percha is used, but 20 or 30 per cent, of ee with gutta-percha without destroying its qualities.” 168 APPENDIX, The same tree is referred to in Watt’s Dictionary of the Economic Products of India, Vol. III, p. 102. In this, an extract taken from Drury’s Useful Plants of India, suggests that the gum might be usefully utilised as a sub-aqueous cement or glue; or that, on account of its perfume when heated, it might possibly be rendered of some value to the pastille and incense makers. More recently this gum has been analysed by Mr. David Hooper, F.C.S., F.1.C., Quinologist to the Government of Madras, and the results are given in the Annual Report of the Cinchona Plantations of Madras for 1891, p. 18 :— “Indian Gutta-percha,—An abundance of gutta-percha milk has been yielded during the dry weather in the Wynad by the Panchotee tree (Dichopsis elliptica), and some planters have been asking for information on the subject, and inquiring whether it could be made into a commercial article, The milk has been known for some years to afford what was called Indian gutta-percha or Pala-gum, and has been used as an adulterant of Singapore gutta. General Cullen brought it to notice 35 years ago, and Dr. Cleghorn published a memorandum on the subject at the time. It was reported upon by experts in London, who found that it was unfit for water-proofing purposes, as its solution in coal-tar and turpentine dry up to such a brittle consistence that the fabric is useless, It could be used as a birdlime or cement, and keeps well under water as a cable insulator, especially if mixed with some genuine gutta. By boiling the milk of the Panchotee tree, a white mass separates, which can be kneaded by the fingers, but which becomes hard and brittle when cold, The brittle character of this substauce, I find, is due to a large proportion of a crystalline substance found also in true gutta, and called crys- talban or alban. Crystalban, according to Payen, occurs to the extent of 14 to 19 per cent.in the best kinds of gutta-percha, but - Ihave extracted as much as 69:2 per cent. of crystalban from the dried secretion obtained from Wynd4d. The presence of a large quantity of crystals in this gum, of course, would interfere with its utility, but crystalban is easily removed by boiling alcohol, and the residue consists of a very good and pure gutta-percha. I cannot see why this process could not be used to purify the Indian gum and so obtain an article similar to the Malayan article.” A note on a gum from:a closely allied plant (Dichopsis obovata, C. B. Clarke) received at Kew from Burma appeared in the Kew Bulletin, 1892, p. 215. (Kew Bulletin, Dec. 1892.) APPENDIX, 169 STYRACE. The Varieties of Benzoin. e source of the different varieties of gum benzoin known to com- e, and many points regarding the mode of preparation of the e still, to a large extent, matters of conjecture. Some .) Bayes in their mode of preparation. Mr. Hanbury offers no definite opinion on the iJ ie San Fliickiger, in his last edition, just published, of the C gnosie. Contributions to the elucidation of a subject upon much divergence of view exists among authorities are come, and they become doubly valuable when they are of careful local examination. In London the druggists four varieties of benzoin, viz.— Siam, the costliest variety ; which comes next in value ; Penang, which is a comparative- ition to our Materia Medica, and Palembang, the kind by benzoic-acid manufacturers. Leaving Siam gum, ai from the mainland of Asia, out of account alto- is evident that the nomenclature of the remaining three snot only altogether fanciful, but actually calculated to mang itself no benzoin is produced, and the gum orted by way of that great emporium of the trade of the Indies i is almost entirely, if not wholly, collected in the Palembang gum also is the produce of the same 2 being simply the chief settlement of the residency in the south-eastern part of the island of Sumatra, : of the benzoin of commerce is brought to market, ins some of the least-known spots on earth, of the cultivation and collection of benzoin 170 APPENDIX, in one of the remoter districts of the island, which we owe to Mr. L. M, Vonck, a member of the Dutch-Indian Civil Service, stationed at Sekajoe, in Sumatra, and which is published in the last issue of the Journal of the Netherlands Society for the Advancement of Industry, is, therefore, an acceptable addition to our knowledge of the collection of this important drug and the manner in which it passes into commerce. Mr. Vonck does not refer to the gum, of which he speaks either as Palembang, Penang, or Sumatra benzoin, and it may, therefore, be taken for granted that those classifications are unfamiliar tohim, The gum of which he writes, and which appears the only kind brought into’ commerce from south-eastern Sumatra, is evidently all obtained from one tree, and seems to corre- spond with the kinds known to our druggists as Penang and Palem- bang, So far as his evidence goes, therefore, it certainly favours Dr, Treub’s opinion that there is no difference between the commercial source of Penang and Palembang benzoin. The benzoin-tree (Styra# Benzoin, or, in Malay, pohon Kemenjan, or Menjan) occurs, accord- ing to Mr. Vonck, in various portions of the high and low lands of the residency of Palembang. It grows up to an altitude of about 600 feet above sea-level, cither in small clusters or sporadically between other trees. Formerly little attention appears to have been paid to benzoin-culture. At any rate, the standard writers on the products of the Dutch Indies only mention benzoin as being collected from wild-growing trees in the virgin forests of the Upper Blitie, on the Lalang and Toengkal rivers, and in the wilds of Batang Lakoh in the country of the Koeboes. But the easy nature of the culture, and the high prices which good benzoin realised in former years (from £6 to £8 10s. per picul), acted as strong incentives to the extension of the plantation. There are only a few parts of the residency of Palembang in which the benzoin-tree is either scarce oF non-existent. In some other districts the tree is found wild, but its gum is never collected, nor is the tree cultivated systematically, The principal districts in which the benzoin-tree is systematically culti- vated in gardens are the divisions of Tliran, Banjoeasin, and Moesi Dir, In the Koeboe country, already referred to above, in the virgin forests of which the benzoin-tree was formerly of very com~ mon occurrence, it has now almost been extirpated, The tree flourishes in various kinds of soil, but experience shows a high, dry _ Sandy soil, free from danger of inundation, to. be most fitted for its APPENDIX, . bey & Ri cebattin. On low-lying, rich, and clayey soil the tree grows up re rapidly, but its gum is then of such a poor quality that the ultivation yields little or no profit, On such a soil there is also anger of floods, which are fatal to the tree, Marshy or stony soil } altogether unsuited to the culture. The tree is propagated from he seed, which is of a reddish colour, almost round in shape, and of size ofa marble. It is enclosed in a green shell. When the d-be planter has gathered a sufficient quantity of the seeds, which favourite food of wild beasts of the forest, he plants them out Sometimes the young benzoin-shoots which have grown up d the parent stem are dug out and transplanted among the dy, The object of the plantation on the paddy-field is to secure necessary shade for the seedlings, which would be easily killed the fierce sunlight. Two seeds are usually planted in one hole ; both come up, the weaker plant is generally destroyed. If thé kes place by means of young shoots from the parent tree, ts, before planting, are stripped of their leaves, and placed Water i in be clics of about twenty-five, being kept afloat between bamboo sticks, When fresh leaves have grown upon the shoots, are planted out in an oblique hole, which is left open for a time. ew benzoin-tree grows from the roots of the young shoot, after ted his seeds or shoots for the purpose of gathering his first p of juice. By that time the shoot has grown into a fine tree, ching and bearing leaves at the top only, and from 25 to 40 feet ight. When once the tapping of the tree has commenced, its | is almost arrested, and the colour of its bark gradually ges from pale grey to brown. If the tree is left to grow wild, fsight trebles or quadruples, some of the specimens in the virgin being over 250 feet high. The incisions made in the tree are 6 triangular in form, and are made at regular intervals and on systematic and invariable plan. experiments were made to determine whether the sialon any peel properties similar to brucine. In the of the ae and application of the paws to the mouth as ve some irritant matter; the animal restless and much M.—Fiéthy mucus and saliva still flowed from the in smaller amount ; vomiting ~— but now and then 1 not so restless, ae of saliva ceased; animal quiet, no further next experiment °022 gramme of the alkaloid was dissolved solution evaporated to dryness, the residue dis- s of distilled water, and the solution hypoder- injocted into the left hind leg of a small frog at 11-40 a.m, a APPENDIX. The frog was placed under a large glass funnel and jumped about, a tap on the glass being sufficient to make it change its place. 11-44 4.m.—Frog showed no inclination to move; when its back was touched with a glass rod it made feeble attempts to move its limbs ; some loss of power was evident, but there were no’ twitchings of the limbs or convulsive movements. 11-46 a.mM.—The frog did not move its limbs even when tapped on the back; the left leg appeared quite paralysed. 11-50 a.m,—The limbs were quite lax, and might be placed in any position without the animal making any effort to move them. hen placed on its back, it now and then made feeble attempts to move the right leg; then the movements stimulated slight twitchings. After this, and until its death at 12 noon, it lay motionless, the only sign of vitality being an occasional gasp ; limbs flaccid, no convulsions. As a control experiment, another frog, a little larger, was injected with the same amount of brucine. Two minutes after the injection it was perfectly motionless ; there was evidently loss of voluntary power over the limbs, When placed on its back and touched, it made no effort to move, but slight twitchings of the limbs were noticed, which became more marked in about a couple of minutes. Touching the back, pinching the limbs, or even gentle tapping on the table, was now sufficient to produce rather feeble convulsive movements, but there was no spasm, except when thus regularly induced, The frog died about ten minutes after the injection. After death the limbs were not stiff but rather flaccid. Many of the reactions we have described as being afforded by” the alkaloid we have provisionally termed pseudobrucine were iden- tical with those yielded by brucine ; while, on the other hand, certain reactions were quite different. The history of the drug shows that itis employed as a domesti¢ remedy in the treatment of a large number of affections, but there is no evidence to indicate that it is supposed to possess any toxic properties. When we are satisfied that we have obtained the alkaloid in a pure state, its ultimate composition, &c., will be determined. (C.J. H. Warden and Assistant Surgeon Chuni Lal Bose, Pharm. Journ., Aug., 1892.) Oleander as a diuretic and heart-tonic. F. v, Ocfele (Pharm. Pr., Oct. 24, 1891, pp. 2-5) draws stteakitn to the action of this plant as a diuretic and heart-tonic in place of APPENDIX, 3 177 sitalis. He considers an itifasion ef the fruit to te preferable to wt other preparations : the infusion may be preserved from deteriora- the addition of a little glycerine or spirit. Dr. von Ocfele sitors that a maximum dose of 3 of a gram of the raw drug or its valent in solution should not be exceeded in the 24 hours. Nouveaux Remédes, Jan. 24, 1892.) Pet sa _ Hunteria corymbosa, Roxb., Wight Ic., tt. 428, 1294; Bedd, = For. Fl. ii., t. 265. he bark of this tree, a native of the Deccan Peninsula, Coro- del Coast, Tavoy, Penang, and Geylon, has been shown by f (Meded. wit Slands Plant., vii., p. 55) to contain 0-3 per a beautiful violet coloration with Erdmann’s and Fréhde’s Iti is a strong poison, and hasa sharp, burning taste, even » he 10,000. Vinea pusilla. called Mulakapundu i in Tamil,and the ryots of sia ASCLEPIADE ZA. Gymnema sylvestre. oses of 0-3 to 0°4 gram, gymnemic acid acts as an emetic. In ler doses it is stated to be very eet for distinguishing itter drugs. For this purpose 3 per cent, aqueous ing a small addition of et is parce for rinsing the tely before taking the medicine, | obtained by moistening the powdered plant with a tic soda, allowing the moist mass to stand in a per- a as. and then extracting with benzin, After erystalline powder, which is soluble in 100 , se piped in aleohol and insoluble in ether and 178 : APPENDIX, LOGANIACEZE, Strychnine in snake-bite. An interesting illustration of the antagonistic action of poisons is given in a letter we have received from Mr. W. Rushton, addressed to his brother in Tasmania by Dr. Mueller, of Yackandandah, Victoria, in which he states that in cases of snake-bite he is using a solution of nitrate of strychnine in 240 parts of water mixed with a little glycerine. Twenty minims of this solution are injected in the usual manner of a hypodermic injection, and the frequency of repetition depends upon the symptoms being more or less threaten- ing, say from 10 to 20 minutes. When all symptoms have disappeared, the first independent action of the strychnine is shown by slight muscular spasms, and then the injections must be discon- tinued unless after a time the snake-poison again reasserts itself. The quantity of strychnine required in some cases has amounted to a grain or more within a few hours. Both poisons are thoroughly antagonistic, and no hesitation need be felt in pushing the use of the drug to quantities that would be fatal in the absence of snake- poison, Out of about ene hundred cases treated by this method, some of them at the point of death, there has been but one failure, and that arose from the injections being discontinued after one and a quarter grain of strychnine had been injected. Any part of the body will do for the injections, but Dr, Mueller is in the habit of making them in the neighbourhood of the bitten part or directly upon it, (Pharm. Journ., June 13, 1891.) These results are opposed to the experiments instituted by the Commission appointed in India to investigate the influence of artificial respiration, intravenous injection of ammonia, &c., in Indian and Australian snake-poisoning (1874). More recently, A. A. Kanthack (Jr. Physiology, Vol. XIIL., Nos, 3 and 4, 1892) has shown that stryehnine is neither a chemical nor physiological antidote of cobra-albumose ; and he is of opinion that ‘‘no false hopes should be raised or fostered as to a cure by strychnia,”’ BORAGINEZE, The active principle of the Boragines. Schlagdenhanffen and Reeb have examined the roots, stalks, leaves sme seeds of Cynoglossum officinale and Heliotropium europeum. Petr 1 ether extracted from the roots a coloured substance APPENDIX, 179 _ analogous to alkanet red. By subsequent treatment with alcohol an alkaloid was obtained which the authors term cynoglossine. : ; : ; seus na pigeon and death without convulsions. Ina rabbit weighing a dose of about one gram produced narcotism and convulsive (Pharm. Post, xxv., 1,) s received from Afghanistan, under the names of Gaozaban 1-i-gaozaban, the leaves and flowers of Trichodesma molle, DC.; and Aitchison (Notes on Prod. of W. Afghanistan and N.-E Persia p. 12) records the collection of the corollas of Anchusa Retz., to be employed as Gul-i-gaozaban. SOLANACEAE, Lycopersicum esculentum, Miller. tomato fruit has been chemically examined by G. Briosi and Qn an average the fresh fruit contains: Seeds 10:9 per 54 per cent,, and skin 3-7 per cent. The pulp can. be ted into a yellow juice and a red residue, which is tasteless washing ; ; the juice on an average has the specific gravity 217, and contains levulose, citric acid (0°4 to 0°65 per cent. of ce), albuminoids, and ash which is composed of 60 per cent. salts. Minute traces of alkaloid are indicated; tartaric could not be detected, The red residue will impart its colouring ‘to ether, alcohol, chloroform, and aqueous alkalies. The solution is not changed by ferrie chloride, dilute acids or addition of strong nitric acid a transient blue colour is 1e residue on evaporating the alcoholic solution becomes adding sulphuric acid ; the colouring matter resembles that . (Chemiker Zig., 1891, 205. Mr. Frederick Davis has found that English-grown tomatoes sub- d to distillation with water afford a volatile substance analogous oil of onions or garlic. The crade oil obtained by distilling ight pounds consisted of oxide and sulphide of allyl. The 180 APPENDIX, ernde oil was acted upon by metallic potassitim to separate the oxygenated product, and the pure oil removed; this upon analysis proved to be represented by the formula (C*H°)*S, (Vear-book of Pharmacy, 1892, p. 515.) Solanaceous Alkaloids. The surprising statement made rather more than three years since, by Messrs. Schering, that belladonna roots contain practically only hyoseyamine, and that atropine obtained from them is probably a product of change oceurring during the manufacture, suggested to Dr. Schiitte to undertake a thoroagh investigation of the subject, and he has just peblished his results in a long and interesting paper (Archiv, Oct. 30, p. 492). In the first place the influence of methods ef preparation upon the conversion of hyoscyamine into atropine was tested, Dr. Will had already stated that contaet with an alkali is sufficient to effect this change, and Dr. Schiitte found that the same result is produced by repeated recrystallizations from acidulated water, as well as by long keeping of hyoscyamine in solution or in the form of a gold salt. It was further ascertained that in fractional precipitation the gold salt of atropine, if any should be present, is thrown down before that of hyoseyamine, and the inference has been drawn that if any atropine gold salt be thrown down at the commencement of the precipitation in a properly-conducted experi- ment, it represents atropine existing as such in the plant-part, and that any obtained from a mother-liqnor after the removal of the hyoscyamine represents a produet of alteration. The influence of | age and period of vegetation upon the alkaloids in the roots was next investigated. Itwas found that young fresh roots (1 to 2 years), collected from a basaltic district, ‘whether gathered in the Spring, summer or autumn, contained only hyoscyamine, but that older roots (8 years and upwards) always contained, besides much hyoscyamine, a little already-formed atropine. Similar results were obtained with roots from old cultivated plants and roots that had been kept several years. The amount of alkaloid was consider- ably greater in the roots collected in summer than in the spring roots, and fell off again in the autumn, but more rapidly in the old than in the young roots, The avérages obtained at the three periods were for young roots 0-127, 0°452, and 0:458 per cent., and for old roots 0-174, 0°358, and 0-280 per cent. Spring and autumn APPENDIK. 181 leaves of the belladonna plant both contained principally hyoscya. mine, with small quantities of ready-formed atropine, As to the fruit, the unripe berries of the wild plant contained chiefly hyoscya- mine and a little atropine, but the ripe fruit contained only atropine. The ripe berries of cultivated plants, however, yielded both hyoseya- mine and atropine, while the ripe berries from var. lutea gave old stramonium seeds yielded chiefly hyoscyamine, together with q i istics of already-formed atropine, and scopo ola amine. The ent in Solanum nigrum and Lycitum barbarum. Nicotiena tabacum also yielded traces of a mydriatic alkaloid, and were detected. Pyridine was the chief base in the smoke 182 APPENDIX. from pipes, while collidine was the prominent base in cigar-smoke, Vohl and Eulenberg conelude that the nicotine of tobacco is com> pletely decomposed during the process of smoking, and that the intense action of tobacco-smoke on the nervous system is due to the presence’ of bases of the pyridine series. There is no doubt that some observers have mistaken these bases for nicotine; but Melsen’s experiments (Dingl. Polyt. Jour., xlvii., 212) appear to be conclusive as to the presence of nicotine, which that chemist isolated in @ condition fit for analysis, and to the amount of about 33 grammes for 4! kilogrammes of tobacco smoked, gr about one-seventh of the quantity originally present. (Allen’s Com, Organ. Anal., iii., pt. 2.) A. Gautier has since observed that the volatile liquid products formed when tobacco is smoked in a pipe consist chiefly of basic compounds. They contain a large proportion of nicotine, a higher homologue of nicotine Ct!H'°N*, which pre-exists in tobacco leaves, and a base C°H’°NO, which seems to be a hydrate of picoline, Other less volatile bases, including hydropyridines, are also formed. These alkaloids result from the decomposition, at a comparatively low temperature, of the earbopyridic and carbohydropyridic or analogous acids present in tobacco, (J, Chem. Soc., April, 1893.) - The alkaloidal contents of the Seeds and Tincture of Datura Stramonium. The principal constituents of stramonium seeds, according to Fliic- kiger and Hanbury’s Pharmacogr aphia (p. 461), are an alkaloid, existing in combination with malic acid, and a fixed oil, of which the seeds are said to contain 25 per cent. The alkaloidal ot aay was first isolated by Geiger and Hesse in 1833, and i submitted to examination by Von Planta, who came to the anole that it was identical with atropine. This statement was subsequent- ly confirmed by E. Schmidt (Ber. der Deutsch. Chem, Ges., xiii., 370), who, however, afterwards modified his views, and concluded that daturine was really a mixture, in varying proportions, of atropine and hyoscyamine (Archiv. der Pharmacie, xxii,, 32 Ladenburg also showed (Berichte Chem. Ges., xiii., 909) that stramonium contains two alkaloids, which he designated heavy and = daturine, the former consisting of mewine and pie aah and the latter of hyoscyamine only, : APPENDIX, 183 © As to the distribution of the alkaloid in the plant, and the com- parative strength of the sceds and the leaves, very little reliable information is obtainable. _ _Hurtz and Hopp (Annal der Therap., 1862, p. 22) inferred, from experiments made by them, that an extract from the seeds possessed five times the physiological activity of an extract from the leaves, Evidence of this kind is, however, of very little value unless the pro- rtionate amount of extract obtained from the seeds and the leaves of the seeds is given in Pharmacographia as 1 per cent. and _ that of the leaves as “02 to -03 per cent, ¢ Hurts (Druggists? Circular, Aug., 1884) reports having obtained eld of daturine from the seeds of «167 per cent. E. Schmidt (Year-book of Pharmacy, 1885, p. 242) obtained from 5 kilos of each of four specimens of seeds, 12°5, 18-4, 2°6, and 10-2 grams alkaloid, equivalent to a percentage yield of °25, °37 *05, and +20 respectively. A. B. Lyons (Manual of Practical Assaying), estimating the oid by titration with Mayer’s solution , found the average yield kaloid by five specimens of the seeds to be from °45 to °55 per and that from eight specimens of the leaves to be °40 to 25 fav w results could be trusted, they would appear to indicate percentage of alkaloid in the seeds and leaves is practically e, but the process of estimation by titration with Mayer's ves, with a view of ascertaining their relative alkaloidal strength, 3 still needed. obtained, and a series of tinctures made from each, by the focess, with menstrua of 80, 70, 60, 50, and 40 per cent, h (by volume), Itwas remarked that all the tinctures became ; when kept, and all threw down a more or less abundant J per cent. tinctures apparently consisting of fatty matter in a ge -transparent crystalline condition, while the deposit from the finctures of lower alcoholic strength was darker in colour and ype O partake more of a resinous character. 184 APPENDIX. In addition to the seed. tinctures, we also prepared, for the purpose of comparison, three series of tinctures from the leaves, menstrua of — the same alcoholic strength, and the same proportion of drug to — menstruum being used, as in the case of the seed tinctures. Before proceeding to the quantitative estimation of the alkaloid, a few preliminary experiments were tried, in order to ascertain whether the process employed for the estimation of the alkaloid in tinctures of henbane and belladonna was equally well adapted for the estimation of the stramonium tinctures, For this purpose 300 c.c. of a standard tincture was prepared with a 60 per cent, menstruum, and the alkaloid estimated by the following processes, the usual precautions being taken to prevent loss of alkaloid in washing with chloroform, &c.:— Experiment I—Fifty c.c. of the tincture was evaporated to low bulk with addition of water, until all spirit had been removed. The residual liquor was allowed to cool and was then acidified with dilute sulphuric acid, and freed from fat and colouring matter by means of chloroform. It was then made alkaline, and the alkaloids removed by shaking with three successive portions of chloroform. From the mixed chloroformie solutions the alkaloids were extracted by three agitations with acidulated water, and were afterwards regenerated from the mixed acid solutions, after addition of excess of ammonia, by shaking out with chloroform. The latter solution was then shaken with ammoniated water, and after separation was drawn off and evaporated, and the residue dried at 100° and weighed. Experiment II,—The tincture was evaporated to low bulk, the residual liquor allowed to cool, and an excess of dilute sulphuric acid added. It was then freed from fat and colouring matter by means of chloroform, a slight excess of ammonia added, the alkaloids shaken out with three doses of chloroform, the latter solutions mixed, and after treatment with ammoniated water evaporated, and the residue dried and weighed. _ Experiment III.—The tincture was evaporated till all spirit was -removed, and the residual liquor acidified with dilute sulphuric acid and shaken with chloroform and ether in turn, till the latter came : ee iontiaen. The alkaloidal solution was then made alkaline ; the alkaloids shaken out with three successive 15 ¢.c, _ — 185 ether (sp. gr. +717), the mixed ethereal. - solutions evaporated, and the residue dried and weighed. | Experiment IP. —The tincture was ‘Se apaneeed to remove the spirit, the residual liquor acidified, and colouring matter removed by his solution treated with a slight excess of ammonia ; the alkaline liquid shaken with three successive portions of ether (sp. gr. PTH, » mixed ethereal solutions evaporated, and Lg? residue dried at V. —This was conducted exactly as No. II., the ai moved by i means of Sips eer ether before the preliminary \ = chloroform : ae I. 50 c.c. tincture = 014 gram alkaloids, _ \ Experiment Il, 50ec. ° ,, = °015 vf oil ‘in ‘the’ say and also showed that my Pr fctcereri ‘treatment with petroleum ether, in order to remove the oily” matter, s unnecessary. Confirmatory experiments with a 70 per ‘cent. ture, by processes IT. and V., gave the following results: No. II. 50 c.c, tincture = -015 gram alkaloids, : ee Y. 50 cle’ 5" Se e exact details of the process adopted are as follows :— ¢.c. of the tincture to be estimated is introduced into of por- 186 APPENDIX, well shaken. After separation the chloroform is drawn off, and the process repeated with 10 c.c. chloroform. The washings are mixed and freed from traces of alkaloid by shaking with three successive small portions of acidulated water, and these are separated and added to the original solution, The latter is then made alkaline with ammonia, and the alkaloids extracted with three successive 15 c¢.c, chloroform, To obtain the alkaloids in a pure condition, they are withdrawn from solution in chloroform by agitation with three successive small portions of acidulated water, the mixed acid solutions made alkaline with ammonia, and the alkaloids taken out by agita- tion first with 10 c.c, and then with two successive 5 c.c, chloroform, In cases where the final acidified aqueous solution was not colourless, the process of shaking out was repeated. The mixed chloroformic alkaloidal solutions were afterwards shaken with ammoniated water, and after separation were drawn off and evaporated over a water- bath, and the alkaloidal residue heated at 100° until the weight was constant. The above process was found to be applicable to the majority of the tinctures without any modification; but with others greater difficulty was experienced than had been the case in any of the estimations previously made. This arises from the fact that in many specimens of stramonium seeds there seems to exist some substance soluble both in alcohol and water, and not removable by chloroform either from an acid or alkaline liquor, and which possesses the property of emulsifying chloroform when that liquid is shaken up with a solution contain- ing it. No difficulty was experienced in removing the oil and colouring matter, but when the extract was made alkaline and shaken with chloroform, emulsification took place, and the chloroform refused to separate out clear, even after standing for some hours. Separation ‘into two layers did, however, take place, the upper layer consisting ‘of a brown alkaline mother-liquor, and the lower layer of emulsified chloroform containing the alkaloid in solution, and holding in ‘suspension some of the mother-liquor. It was ascertained bare all _ the alkaloid was taken out by the chloroform, and two eS oe “were devised, yen it could be extracted from the aoeebietlt | _ and o in a pure condition. By the plan first the original alkaline liquor was “shaken — st APPENDIX, 187 . —— 15 ¢e.c. chloroform, and after separation these were drawn water, by which means all the alkaloid was taken out, together with the mother-liquor included in the chloroform magma, and olu shaken with ammoniated water, and after separation drawn off and evaporated and the residue dried at 100° and weighed, The of alkaloid by this process is very slight, and there is no waste roform, the same portion being employed all the way through ‘shaking out the alkaloids, a fresh quantity being used only for final extraction of the pure alkaloid. The process, however, was ong and tedious one, each estimation occupying four or five off et Geijostion and the residue dried at 100° and weighed. two modifications of the process of estimation were tried side 188 APPENDIX, by side on four of the most troublesome samples of tincture, and the results in each case were exactly concordant, ~The alkaloid as obtained by either of these processes is in the form of a perfectly colourless, transparent fused mass, It is soluble in water and dilute acids, and the reactions generally correspond with those of the alkaloidal residue obtained from the belladonna tinctures. A glance at the table will show that the most perfect exhaustion of stramonium seeds is effected by the use of a 69 or 70 per cent, men- struum, the average yield of alkaloid by the tinctures prepared with menstrva of these strengths being equal. It is open to question, however, whether a better preparation could not be obtained from the leaves. The chief objections to the tincture prepared from the seeds are that it almost invariably becomes turbid and deposits when kept, and also becomes opaque on dilution, which Pigeons do not apply to a 50 per cent, tincture of the leaves. The results of the examination of the leaf-tinctures are appended to the table, The leaves from which No. 1 series was prepared were gathered from plants grown by one of us (Farr), and the deficiency _ of alkaloid is doubtless accounted for by the persistent rain and lack of sunshine which characterized the past season. The tinctures made from the other two specimens, however, gave the same average of alkaloid as the seed-tinctures, Lyons’ results, referred to above, go to show that the alkaloidal strength of the seeds and leaves is the same, and should this fact be established as the result of further work upon the subject, we should recommend that this tineture, like those of henbane and belladonna, be prepared from the leaves, on the ground that a 50 per cent. tincture of the leaves is a more elegant pharmaceutical product than a 60 per cent, tincture of the seeds. The results tabulated go to prove that the alkaloidal content of stramonium seeds does not vary to anything like the same extent as does that of most other drugs, the yield of the tinctures varying between the limits of -020 and ‘034, with an average of -026 per cent. This tincture, like those of henbane and belladonna, readily admits of standardization, and the standard should be fixed not lower than © 025 per cent. = The average amount of alkaloid contained i in the 0 Reais calculated : menage oe Pasty “2 per cent, APPENDIX, ‘189 ‘The percentage amount of the extractive in tinctures was ascer- tained by evaporating 10 c.c. of the sample over a water-bath, heat- ing the residue at 100° till the weight was constant, and hace hg the result by ten, : It Bit be-remarked that the last five series aftinctures shoves Ge mah yield of extract than the first six, and it will also be noticed at the difference is more marked in the case of the tinctures pre- red with the stronger menstrua. This discrepancy is accounted r by the a, that series 1—6 were made, as the armacopeia e bruised seeds, while the drugs employed i in the bration a series 71] were reduced to somewhat fine powder adbea ng ¢ oT into lke We have previously iat and as a consequence the prepared with the sexouiges menstrua with a ty hs sc and i in all jeter inert matter. This is sev: : Table showing Quantitative Results of Estimation of Samples of Tincture of Stramonium Seeds. ad ei : Amount of alkaloid in grams from 100¢.¢, tincture. | Amount of extractive in grams from 100 c.c. tincture. No. of Sample. 80 . | 60 p.c p.c. | 40 p.c. | 80 p.c. | 79 p.c. | 60 p.c. | 50 p. | 40 Pp. c. tincture. | tincture. | tincture, | tincture. | tincture. | tincture. | tincture. | tincture. ps 9 | tincture. : | re et 084 0382 “030 030 52 54 54 60 al ee ; e 2 026 024 022 52 “50 56 6 55 ris ne - 021 024 023 024 017 52 “2 69 ere is 030 028 027 "030 029 *48 58 54 52 50 > ae ve s 029 028 028 i 026 59 61 64, 78 70 _ eae cs é 020 024 025 ‘O24 018 72 78 80 Bo Das see wel 7 O20 027 0295 *023 2 5 1°62 118 74 74 a ee 021 025 "0245 “019 0205 | 1-76 1M6 1:24 90 ‘70 2 ae 019 020 015 1 2 92 62 52 ra 10 bee tee tee "020 023 024 021 015 1°00 78 "68 6U PALS sis tee wat “ORT 2 023 020 ‘018 1°34 1:14 88 74 58 Average ... ...| ‘0285 0258 | -0256 | *"Oz84 | -o209 | 102 “90 | 77 ‘67 ‘64 Results of Estimation af Leaf-tinctures. 2 ee ie ; o12 015 14 ‘014 013 1°60 2°08 2:20 2°46 2°94 eee = : 024 ‘028 ‘028 ‘028 028 2°04 2:48 2°68 2°80 2°82 ae oe 022 022 ‘023 02 022 1:90 2°04 28 294 3:08 * Series No, 3 was made from seeds gathered in 1889, (Ly E. H. Farr and R, Wright, “ Pharm, Journ,” Jan. 16th, 1892.) APPENDIX, 191 ACANTHACEAE. Note on the presence of a epireee leg in the roots of Hygrophila spin In the Pharmacographia Indica, one of us described the physical properties of a principle isolated from the roots of the Hygrophila spinosa, which was not unlike a cholesterol. Subsequently, through the kindness of Dr. Dymock, we obtained a large supply of the roots, and were able to separate a sufficient amount of the material to admit of its thorough purification and ultimate composition being determined. _ For ultimate analysis the principle was crystallized from light petroleum ether, and the combustion made in an open tube in a -_ eurrent of oxygen. The tube had been in use some time and was ie in very good working order. The results obtained led to the follow- i: aa our a axe ies Be ee 83-86 83-80 see a eee 44 11-82 12°02 ne z : Oey 16 4°32 418 eth 100°00 ‘00 100-00 At 175° C. ania the cholesterol Sa aceanaueae ae to soften, and melted at 184° (uncor.). The fusing point would appear to be higher than that of any cholesterol hitherto isolated. We were unfor- tunately unable to determine the specific rotatory power. In purifying the cholesterol an alcoholic extract of the root was dried and exhausted with ether. The dry ether extract was treated : with dilute sulphuric acid, and the insoluble residue taken up by eth The ether extract was next boiled with aqueous caustic 4 4 tash, the solution evaporated to dryness, and extracted with petroleum ether. The petroleum ether extract was boiled for some _ hours with alcoholic potash, the solution evaporated to dryness, and = with petroleum ether. he ee extract was of a a this, however, failed to remove the whole of the colour, and the following experiment was adopted. The alcohol was evaporated off, 192 APPENDIX. the residue dissolved in petroleum ether, and the solution agitated with proof spirit ; by this means most of the colouring matter was removed. The cholesterol was finally several times crystallized from petroleum ether, and was obtained perfectly white. A benzoyl derivative was also prepared, Evaporated with a drop of nitric acid and the dry residue moistened with ammonia, an orange colour developed, but no change was induced by the addition of caustic potash, The violet reaction with ferric chloride and HCl applied as described by Forti was very marked. The sulphuric acid and chloroform reaction was conducted in a stoppered bottle ; the chloroform layer at first became yellowish-brown, then blood-red, finally darkening to reddish-purple ; the sulphuric acid and stratum was of a pink colour, and in some experiments fluoresced, (By C.J. H. Warden, and Assistant Surgeon C. L, Bose, Assistant Chemical Examiner to Government of Bengal.) LABIATZ. Salvia macrosiphon, Boiss. The Kanocha seeds referred by us (Vol. IIL, p. 265) to Phyllan- thus madraspatensis have been shown by Dr. O. ‘Stapt to belong to a species of Salvia. Dr. Stapt bought the drug in the bazaars o Ispahan, where it was known by the Persian name Marv. A drug called “ Merw” was mentioned by Abu Mansur in 1055, and Selig- mann refers it to Origanum Mary, L., a native of Syria. Aitchison, in his Notes on the Products of Weatthn Afghanistan, mentions ‘Salvia (?)” as the origin of the nutlets known as Kanoucha or Kanouncha. (Pharm, Journ., March. 11, 1893.) Influence of Menthol on the gastric functions.* Following Professor I. T. Tchiidnovsky’s suggestion, Dr. Vladi- mirsky has carried out a set of experiments on seven healthy subjects (six men, including himself, and one woman), aged from 24 to 32, the drag being administered with food, in’ the dose of 0°3, 1-0 and 20 _ grammes. The author has arrived at the following conclusions :-— (1) The drug (in any of the doses stated) very markedly dimi- ‘inion the proportion of free hydrochloric acid in the gastric juice, the decrease attaining its maaimusn in about 1 or 1} hours after APPENDIX. 193 (2) In persons presenting a more or less weakened motor power f the stomach, the decrease lasts longer than in those with a normal (3) The digestive power of the gastric juice is diminished. ) The transformation of proteids into peptones is retarded (hence preased proportion of propeptones, t.e., intermediary products of . ation). The proportion of Lanite acid in the gastric juice is aug- the rise proceeding parallelly with diminution in the propor- ydrochloric acid. r power of the stomach grows weaker (in about one gestion); in initial stages of the digestion, however, y undergo some increase, ‘ptive power of the organ improves, which seems to pon a favourable (stimulating) influence of menthol Largrgloy and Rha ynology, May, 1890, p, 202), L. Breddois S. Rosenberg, Hugo Koster, and many other observers, ot appear to possess any special “ appeitecn al nes ?. doses, the remedy aa Boke DEY ei by sensations of languor and . Viadimirsky.) _ Ustukhadus and Gul-i-sirwaj. esc from Afghanistan, under the name of we received, under the name of Gul-i-sirway, red calices of Hymenocrater elegans, Bunge, ; the calices have au agreeable aromatic 194 | APPENDIX, ARISTOLOCHIACEZ. Aristolochine and Aristin. These two substances have been obtained from the roots of Aristolochia argentina by Dr. QO. Hesse, who gives the following account of them (Pharm, Journ., Jan. 9th, 1892):— The powdered root gives a dark brown yellow colour to ether, and when gaseous ammonia is added to the ethereal solution a red flocculent precipitate is separated. The ether solution separated from this precipitate gives on evaporation a yellowish-brown residue, in which clear, colourless crystals are formed after some time. The dark-coloured mass separated from these crystals and again dissolved in ether gives, on shaking with dilute sulphuric acid, a sm quantity of a base. The greater part of it, however, remains in the root that has been treated with ether, and can be extracted with alcohol, On evaporating the alcoholic extract a brownish-yellow resinous residue is obtained that is partly dissolved by caustic soda solution and gives up the base to ether. . I propose to apply the name Aristin to the substance contained in the above-mentioned red ammoniacal compound. When that” ‘com- pound is dissolved in hot glacial acetic acid, the aristin crystallizes out on cooling, and it can easily be obtained in a pure state by recrys- tallizing from hot glacial acetic acid. Aristin forms shining gold- coloured laminz and flat needles sparingly soluble in hot glacial acetic acid and searcely at all soluble in the cold. It is sparingly soluble in hot alcohol, more so in ether, chloroform, or benzene. ‘At about 260° C. it blackens, but does not melt until the temperature reaches 270° C., and then undergoes decomposition. It dissolves in concentrated nitric acid on boiling for a short time, and separates again unaltered on cooling ; but when the boiling is long continued decomposition takes place with evolu- tion of red vapour.’ Aristin dissolves in acetic anhydride with a yellow colour, and when concentrated sulphuric acid is dropped into the solution it becomes at first intensely blue and then pern#mently greenish-blue. The alcoholic solution of aristin : has a perfectly neutral reaction, but the substance combines with — ammonia soda. These compounds have a fine red cdl ee aleoher ‘in \ APPENDIX. _ | 195 ee alcohol with deep orange-red coloration; On addition of acids to these solutions a flocculent yellow precipitate is thrown down which scon becomes crystalline. The second of the above-mentioned compounds is a fat acid ester that can be easily purified by recrystallization from alcohol, It takes the form of small white lamin which melt at 84° C. +, and are very soluble in hot alcohol, but sparingly in cold alcohol , very soluble in ether, pertroleum spirit or chloroform, and insoluble in water. The substance dissolves in hot glacial acetic acid, and on coolin erystallizes out again unaltered. In the alcoholic solution this substance can be easily saponified, the products being phytosterin and palmitie acid, he third substance mentioned above is a base, to which I propose giving the name Aristolochine. That name has already been applied by Chevallier to a bitter substance obtained from Aristolochia serpentaria, but it was obviously a mixture the bitter taste of which was probably due to the presence of the base now described. There- fore, the name seems to me to have been inappropriate in that instance, and I have transferred it to the pure substance. Aristolochine is precipitated from its colourless solutions in sulphuric or acetic acid on the addition of ammonia or caustic soda in the form of white amorphous flocks. It is freely soluble in alcohol, ether, chloroform, or benzene. On evaporating the ether solution it remains as a colourless resinous mass. When the ether solution is mixed with an equal volume of petroleum spirit and the mixture very slowly evaporated, warty masses are deposited that are distinctly crystalline. The base has a bitter taste and neutralizes acid perfectly. The hydiodide and sulphocyanide are amorphous oily precipitates which present no tendency to crystallize. The platinochloride is a dark yellow and the aurochloride a pale yellow amorphous precipitate ; both are almost insoluble in water, The behaviour of the base with concentrated sulphuric acid is remarkable. It forms a fine green solution, which becomes bright bluish-green on the addition of a trace of ferric chloride. Similar reactions are given by aricine, cusconine, and some of the bases of the bark of Remijia purdieana. a appears to have been already observed by Dymock and Warden in their examination of dristolochia indica, and I am of opinion ce the differences of their statements in regard to the base 196 | APPENDIX. are solely due to their having failed to separate it completely from colouring material. I am also of opinion that aristin partakes of the nature of the yellow substance* obtained by previous observers, and that, according to some remarks of Dymock and Warden, it is probably present in the root of Aristolochia indica; Aristolochin is the name given by Dr. J. Pohl to the active principle of the seeds of Aristolochia Clematitis and the roots of A. rotunda and A, longa. The powdered drugs were exhausted with petroleum-ether, which removed chlorophyll, oil, and a gelatinous, nitrogenous, inactive substance (occasionally this can be obtained crystalline); warm 96 per cent. alcohol removed the colouring and bitter principles; after evaporating to syrupy consistence it was taken up with water and acidulated with sulphurie acid, the preci- pitate collected, expressed, dried at 40° C., and extracted in a Soxhlet apparatus for some weeks with petroleum-ether until the last traces of the above-mentioned nitrogenous substance were removed and the residue exhausted with aleohol or ether; from this alcoholic or ethereal solution there separated after a time yellow erystalline masses, which, recrystallized several times from ethereal solution, — were found to constitute the active principle. It is soluble in chloro- form, ether, acetone, phenol, acctic anhydride, aniline, and aleohol ; almost insoluble in cold water, slightly soluble in warm water ; insoluble in pertroleum-ether, benzol, and carbon disulphide ; alkalies and alkaline-earth hydrates dissolve it; from neutral or alkaline solutions it is precipitated by neutral and basic lead acetate, dialyzed iron, zine sulphate, silver nitrate, and a saturated solution of salt, but not by alum, copper sulphate, and platinic chloride ; it does not reduce Fehling’s solution and does not react with Millon’s reagent. Its ultimate analysis, C 59°98, H 3-54, N 4:32, O 32-16, leads to the formula O™H**N*Q" Physiologically it was found that cold- blooded animals were entirely indifferent to it; while in warm- blooded animals uremic intoxication was produced ; in this respect aristolochin is a much more powerful agent than any other sub- stance ; it resembles aloin in its action upon thefkidneys, but is about ten times more poisonous—it is probable that given to man it may 1891,642.) -* See Pharm. Journ, li, 245 act as a cathartic (Arch. f. exper, Pathol. u. Pharm.). (Apoth, Zig. : APPENDIX. : ee LAURINEA, 2 Gum-barks. Gum-bark, or Pishin-puttai of the Tamils, does not refer to the bark of a tree which exudes a gum by bruising or incision, but denotes a bark which has such mucilaginous properties that it could be used for special purposes in medicine and the arts, where the white of egg would be used elsewhere. Barks of this description occur in the natural orders Malvacee and Laurinex, and students of materia medica know that drugs of these orders, marsh-mallow root, and the barks of arboreous cinnamons, for instance, contain a peculiar muci- lage, which is not precipitated by alcohol. A typical gum-bark of the East is that of Aydia calycina, a malvaceous tree, growing ex- tensively on the slopes of the Nilgiris, and largely employed in sugar rel finery under the Tamil name of Kadularangy ~puttar. On s caling . portion dante becomes coated with a slimy mucilage, e inner layers of _ the liber may then be removed like pieces of lace, and the gum is seen to be occupying the spaces between the longitudinally disposed fibres, apparently formed from the cellulose of the broken cell-walls, The bark of Kydia is sold in the bazaars, and the decoction is taken as an astringent and tonic, and the Vythians or native doctors consider it to be a specific for diabetes. Dr. Mohideen Sheriff, in the “‘ Supplement to the Pharmacopeeia of India,” gives Tetranthera Roxburghii as the botanical origin of Pishin-puttai, but offers no deseription of the drug under that heading. Mr. Hollingsworth, of the Madras Medical College, some time ago supplied me with an authentic specimen of the bark of Tetranthera laurifolia, or, as it is now called in the “Flora of British India,”’ Litsea sebifera, The bark was of a reddish-brown colour and slightly - palsamic odour, very different to that of cassia or cinnamon. The thickness was a quarter of an inch, and when soaked in water it became very mucilaginous. It afforded, on analysis, distinct - reactions for an alkaloid, which had the characters of laurotetanine, a poisonous base lately discoyered by Dr. ae in the barks of _ several species of Javanese lauraceous plan About two years ago a collection of pan for identification was sent to me by Dr, P. 8S. Mootooswamy, of Tanjore, and among them was a specimen of Pishin-puttat, which, he said, was collected trees growing in the jungles near Point Calimere. This bark 198 APPENDIX. had a most agreeable odour, resembling, but not identical with, Indian cassia, and the taste was decidedly sweet. It made a slimy mucilage when mixed with water and contained some tannic acid, but no alkaloid resembling laurotetanine could be separated from it, The bark is sold in the bazaars, and itis known as Mydalakady among Muhammadans, It is used in medicine for its mucilaginous, demulcent, and refrigerant properties. By powdering the bark with some benzoin, mixing it into a paste with a little water, and smearing this on reeds, and drying them in the sun, flavouring sticks called Samboorany-vathe are made, and are burnt as an incense or perfume, I have not been able to obtain the botanical source of this particular variety of gum-bark, but I am inclined to believe from its odour that it is an arboreous cinnamon. From Travancore Ihave received on different occasions thre specimens of gum-bark, all varying the one from the other, The first was a thick, red-coloured bark, a commercial article on the Western Coast, supplied to sugar refiners. The botanical origin could not be ascertained; it differed in physical characters from the barks previously mentioned, and yielded an alkaloid having the reactions Of 9 laurotetanine. Probably it was a Litsxa. The second description of gum-bark was that of Kydia calycina. The third specimen was sent by the Conservator of Forests for Travancore ; it was named in Malyalum Ava-tholi, and derived, it was supposed, from a species of Cordia. I have recently examined some samples of gum-barks from the Madura District of Southern India, and stated to be used by the hill villagers in increasing the alcoholic strength of sago toddy. The plants yielding these barks were up to this time only known by their vernacular names, but as leaves, flowers, and fruits were also sent, these enabled them to be identified. The request was also made that they should be analysed to ascertain the nature and effect of their use in native spirit manufacture. The seven specimens of bark were as follows :-— 1. Kadaly-marum* ... ... Olea glandulifera. 2. Koppa-marum __... ... Litsea Zeylanica. 3. Karukathan-gundu* . Hiptage Madablota. was -. Jasminum flexile. Pungala-marum ... ... Ligustrum Roxburghii, ss .. Litsea Wightiana. la-marum ... we. Gmelina arborea. | * Marum=tree, gundu=climber (Tamil). : APPENDIX. 199 ~The Olea ait ig is a stout, tall tree, with white flowers and small black fru e bark is of a greyish colour, with whitish specks, about 3 a an hah in thickness, breaking with a close granu- lated tieture, inner surface brown. The Litsea cages is a moderate-sized tree, with yellowinh-whie flowers and ruit ; the leaves are ribbed and whitish on the __- under surface. “The bark is gray and covered with lichens, smooth, 2 of an inch thick, fracture close, showing white, glistening fibres running through the red substance of the middle and inner layers, brown and smooth internally, The bark gives off a fragrant odour when burning. _ The Hiptage ORL is a woody climber, reaching to the top of trees over 100 feet high. The stems are from half to three- quarters of an inch in een and covered with a thin, smooth, lish-brown bark enclosing a yellowish wood. e Jasminum flexile is also a climber. The stems are about one ch in diameter, very woody and knotted, covered with a light lowish- brown papery bark, exfoliating on the surface. The Ligustrum Roxburghit is a stout tree about 50 feet in height, The bark is coloured russet-brown, and is a quarter of an inch or more in thickness; fracture close, showing thick white fibres running the brown middle and inner layers. ‘The tages Wightiana is similar to L. Zeylunica in many respects, The bark has a greyish-green epidermis, beneath which is a chocolate- coloured surface ; the fracture is short and light coloured, becoming red or brown by exposure to the air, The Gmelina arborea is a common tree in the plains. The bark is about half an inch thick, with a rugged, black and yellowish-brown Burtace, middle layer hard and brown, fracture granular, ochreous hb documents accompanying these specimens stated that the barks of these trees were used ‘to increase the intoxicating effects of sago toddy.” The bark is simply placed in the toddy and left there for two or three days. The bark No, 3, it is said, is not so frequently used, as the resulting liquor causes honiaske when drunk. ith reference to No. 7, it was said that a tenth part of it would x the purpose in the absence of other barks. will only be necessary to give the results of the chemical ation of these barks, in so far as they are likely to explain 200 APPENDIX. their action in the fermentation of sugar, Three of the plants _ curiously enough belong to the natural order Oleacex ; these are Olea glandulifera, jasminum and ligustrum, and like other plants of this order contain a peculiar bitter principle, soluble in water and alcohol, and a yellow colouring matter called quercetin. Two other barks of the series belong to the same natural family of the laurels, and have a similar composition ; these are the Litseas. The Hiptage bark con- tains tannin, and is simply an astringent; and the Gmelina belongs to a class of plants distinguished for their bitterness. The amount of extract dissolved out of the bark by water and aleohol respectively were determined in order to ascertain their relative proportion, as it would seem that in the absence of much resin, the excess of water extract over the spirit extract would indicate mucilaginous matter, and on the barks being placed in the toddy, which in a fresh state is a watery solution of sugar, with some albuminous matter, the extract would dissolve, but as fermentation proceeded, alcohol would be formed and the mucilage would become insoluble and precipitate, carrying down with it the viscid albumen, and thus allow the s sugar to Berean more Rr aera From the ; that other gum-barks besid > L as Ky: and Guazuma tomentosa, are Pleas cused ie eo ‘sugar, it is evident that some such object as this is intended in their employment, The astringent qualities of most of the above-mentioned barks are no doubt used for the purpose of forming insoluble compounds with albuminous matter in saccharine solutions; just as hops are used to remove this substance from malt liquor in the ordinary process of brewing beer, The hops are found to prevent in a great measure the tendency of the beer to become sour, in consequence of the conversion of alcohol into acetic acid, and in warm climates where ~ such liquors are apt to run into the acetous fermentation very rapidly, it is necessary to employ astringent drugs to regulate the formation of alcohol and prevent the development of acetic acid. The natives consider these barks a necessary ingredient in making ‘spirit, for the following reasons: Firstly, they diminish the great sweetness of the toddy sugar. Secondly, they render the spirit more ntoxicating. The first of these phenomena is accounted for by the fact that-sugar breaks up during fermentation into two alcohol and carbonic acid ; ste ed ae the to ob 02 hol from APPENDIX, 201 ‘i his toddy than he could get from leaving it to brew without such ad- juncts. The analyses of the barks, with the exception of the Litszas, _ which contain laurotetanine, has revealed no principle of poisonous or intoxicating properties, therefore the idea of their directly communi- eating a potency to the spirit is not sufficiently established, and, besides, as the spirituous liquor is submitted to distillation afterwards, 8, any alkaloid, such as strychnine, would be left behind in the retort, Some of the barks are aromatic, and these most likely are used to flavour the resulting spirit, which would be the case if the aroma resided in a volatile oil. It is probably a spirit of this kind that Dr, Ainslie refers to under the title of Puttaicharagum, or bark-spirit, an alcoholic liquor in which barks of various aeacias are used in the manufacture, (D. Z. Formosa Camphor.* _ Formosa camphor is obtained from the Lawrus camphora, immense forests: of shits extend over most of the lower ranges of hills in the island, extending up the lower slopes of the mountains inhabited by the savage tribes. Many of these forests have not been touched, and the statement that the camphor supplies in South Formosa are becoming exhausted, applies only to those districts which are purely Chinese. The supply from other parts is practically inexhaustible. Even in purely Chinese districts it is only at certain places that the supply is falling off in consequence of the reckless manner in which the trees have been destroyed, partly for the sake of the timber and eamphor, and partly, no doubt, simply to clear the ground for cultivation. It has been often stated that the method of obtaining crude camphor in Formosa is by steeping the chopped branches in water, and boiling until the camphor begins to adhere to the stick used for stirring, when the liquor is strained, and by standing the camphor concretes, By this method it does not necessarily follow that the tree is destroyed; in fact, with a little care there is no need that it should be. But although this method may have been in use in former days, it certainly is not now. On the contrary, I am assured __ by several natives, engaged in the trade, whom I have questioned on ‘ the subject, that the yield of camphor from the branches is too y the labour of extraction. m a report by Mr. Scot A hcseonc, tae sescarek lah Formosa. 202 APPENDIX. Tke method in general use now is as follows:—The camphor expert selects a tree and scrapes into the trunk in different places, using an instrument somewhat resembling a rake, with the view of ascertain- ing whether it contains sufficient camphor to repay the labour of extraction. A tree is said not to be worth anything for camphor purposes until it is fifty years’ old, and the yield is very unequal ; sometimes one side only of the tree contains enough camphor to satisfy the expert, and in this case that side alone is attacked. The trunk is scraped to as great a height as the workmen can conveniently reach, and the scrapings are pounded up and boiled with water in an iron vessel over which an earthenware jar, specially made for the purpose, is inverted. The camphor sublimes and condenses on the jar, which is removed from time to time, scraped, and replaced. The root of the tree and the trunk, for some eight feet up, contain, as a rule, the greatest quantity of camphor, If the scrapings obtained from the trunk yield well, the chipping ,is con- tinued until in the end the tree falls. The roots are then grubbed up, as it is certain they will give a proportionately good return, If, however, the scrapings do not turn out well, the tree is abandoned, — and work is commenced on another, No attempt is made to extract La camphor from the fallen trunk or from the branches. In some ‘eases, the trunk is sawn up into timber, but this depends on the locality ; from many districts, owing to absence of roads, timber would not pay for its transport. It is impossible to imagine a more wasteful method of procedure, and it is fortunate that the camphor forests of Formosa are practi- cally inexhaustible. _ The quantity of camphor produced depends, of course, simply on the amount of labour employed in the business. Ten of the iron pots mentioned above and their accompanying jars make up what is called a ‘‘ set,” and are worked by four men, One set will produce about 65 lbs, in ten days, or, say, 18 cwt.a month, but this only under the most favourable circumstances; a fair average is about 1} ewt. _ Recently a change has been made in the camphor monopoly. It is _ now proposed by the Chinese authorities that the camphor stills ‘should be licensed before they are permitted to work. The cost of the license will be equivalent to a tax of about 22s. 6d. per cwt., ry tax, seeing that the the actual value of the camphor at the APPENDIX. 203 place of ———* is very little over this amount. = Journ, June 13th, 1891.) El TACK. Phyllanthus Niruri. The bitter principle of this plant, which we fi seetnige.! named pseudo-chiratan, has been examined by M. Ottow (Nederil. Tijds, voor Pharm., 1891, 8, se — ealls it ee and gives its ehemical Sennipoiditiock as 70°, It crystallizes-in colourless needles or flakes, possesses an cases pies taste, and is almost in- soluble in water, but easily soluble in alcohol, petroleum ether, ether, chloroform, benzene, and glacial acetic acid. At 200° C. it is volatilized and condenses in the-upper part of the vessel as an amor- phous mass, but in a few days this sey a deposit changes to, the crystalline state. Manioc or Cassava. From the brief allusions to this substance by writers on Materia Medica, one would get but a slight idea of its importance as an arti- cai Cle a diet in Sirnicial countries, being the staple-food for unnumbered ~~ millions of human beings—the staff of life in the West Indies, Brazil, nae on the Continent of Africa, The plant from which this food is derived is known to botanists as Janipha Manihot, and is a shrub six to twelve feet high and one or two inches in diameter. Except for the young leaves, which are used as greens, its whole value consists in its tuberous roots, which sometimes reach the enormous weight of thirty pounds, but usually range from one to three inches in diameter and from six to eighteen inches in length, The shrub is said to bea native of Brazil, where it is known as Mandioca or Tapioca, Cassada (or Cassava) is its name in the West Indies, Itis not grown from the seeds, but from cuttings, having surprising vitality; for a cane of it, like Aaron’s rod, will bud and grow leaves in your hand. Hence, it is only necessary to cut the _ stick into pieces of six to twelve inches in length, and thrust them into the ground, and it matters little whether the ground has been first broken for itor not. In eight to eighteen months the tubers are in their best state to produce the nutritious food—seventy per cent, gluten and thirty of starch ; but, at a later period, the gluten becomes 204 APPENDIX. less and the starch increases. There is no food-produet which com- pares with it in resisting drought. Even in the dryest seasons, it is like other trees “planted by the rivers of water,” and whole fields are green with its foliage, while all else is brown with the scorching sun, There are two varieties of the manioc, known as the sweet and the bitter; the first of which may be eaten with impunity, while the latter has a bitterish, milky juice, which is poisonous from containing prussic acid. But these roots are grated or otherwise reduced to a pomace, and then suspended in grass bags, when the poisonous juice drips out, or, being volatile, is dissipated by the heat in baking bread from it. The bitter variety is the principal kind used in British Guiana, while the sweet is the one mostly cultivated in Africa, The tapioca which comes into our houses is almost pure starch, and is made from the expressed juice of the root, which, on standing, deposits in the form of powder, and which, if dried without heat, will remain so. If heat be applied, it takes the form of the irregular masses we are accustomed to see, The root has the taste of chestnuts, and may be eaten raw delicious, wholesome food when roasted in hot embers or | $f soaked fill the oki a ne Pee, ee Ibis + # ihe tricans call it oH pinta ? bomba. An extremely white and fine flour, called fuda, is made from the soaked and dried roots, and it is the chief food in Angola. The flour makes a thick porridge or mush—funje. The water is boiled and salted and set off the fire; after which fuda is stirred in until it can be cut into blocks, which may be taken in the hands and eaten with molasses or dipped irito chicken broth. The staff of life on the Congo is guanga, or bread made from the _ manioc by soaking, peeling, and pounding the soaked root into a _ pomace, and kneading and making into dough-loaves of four by six or ten inches. These loaves aré wrapped in thin, tough leaves and bound, and then boiled in large earthen pots, Then the bread is ready for use; or it may be sliced and browned or broiled, as one prefers.” from the manioc is prepared by grating the green root, dry. _ the sun, with all the starch and tapioca in it, browning it _ & APPENDIX. 905 Grate, strain, and dry slowly in the sun, and you have a starch for puddings or any other purpose for which starch has demand in the market. Gluten being a nerve-food, indispensable to health and vigour of both body and mind, the great abundance of it in the Cassada—nearly three times as much as in wheat flour—the Cassada is pre-eminently ‘“ the staff of life,” since there is no way by which its abundance of gluten can be wasted in preparation, as in wheat. There is a Providence here which shapes ends, since this chief food for tropical regions has so much nerve-supplying elements and so little of the heating elements, as compared with food in colder climates. But this abundant gluten, as compared with other foods for the sick, pre-eminently fits it for the sick-room, oe especially so when we wish to increase strength instead of heat, and where any irritating and indigestible food-substances are at, It requires longer boiling than starchy foods in general, and may be use in the form of thin mucilage or demulcent, or in a more solid form with sugar, lemon juice, nutmeg or other aromatics. I suspect that, as physicians, we should make immense gain in restoring from prostrat- ing sicknesses by using more of this eligible substance in place of so much meat slops, and especially so in cases complicated with more or less gastric irritation, Meat foods must be excluded from the stomach in gastric ulcer. Why not, then, fall back upon this highly nitrogenous food for supporting the strength? Having so large a proportion of gluten over the starch, it offers immense advantages over wheaten and other bread in cases of diabetes where any starch at all is allowable. (By E. Chenery, M.D., of Boston, ‘*The Times and Register,” April 5th, p. 318.) - In the Cox’s Bazar district, Bengal, the tuberous roots are used by the Maghs in the preparation of a spirit. A false Kamala. Mr. Henry G. Greenish has examined a sample of Kamala from Bombay, and found it to have been carelessly collected, and mixed with badly preserved safflower and other extraneous matter, and reduced to coarse powder. (Pharm. Journ., March 11th, 1893.)