THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA PRESENTED BY PROF. CHARLES A. KOFOID AND MRS. PRUDENCE W. KOFOID THE RELATION OF ANIMAL DISEASES TO THE PUBLIC HEALTH, AND THEIR PREVENTION. BY FRANK S. BILLINGS, D. V. S., C&.VOCATB OF THE P.KYAL VETKRISART INSTITtTTB OT BKSLI.N ; MEMRCR OF THE ROYAL VETEBINART ASSOCIATIu:< OF THE PROVINCE OF RRAN'DKNBURO ; HOJJORART MEMBER OF TUE VETERINARY SOCIETY OF MOXTBEAL, CANADA, ETC. NEW YORK: D. APPLETOX AND COMPANY, I, 8, A!«D 5 BOND STREET. 1884. COPYKIGHT, 1884, By D. APPLETON AOT) COMPANY. IN MEMORY OF ANDREAS CnRISTIAN GERLACII, L.VTE DIRECTOR OF THE ROYAL VETERINARY ISSTITI'TE, BERLIN, PRCSSIA, TO WnOSE EXAMPLE, LOVE, AND SYMPATHY THE ATTIIOR OWES WHAT LITTLE ABILlfV HE POSSESSES, THIS BOOK IS AFFKOTIONATELT Q tbicattb. \ 710 • PEE FACE » This book is written for the benefit of the people of the rniteJ States, Its purpose is to intruduce to every thinking man and woman of the country a new subject, the higher pur- poses of Veterinary Medicine. It is a work which treats of the Prevention of Diseases, not their Treatment. AVhile at times the language of the author may appear uimecessarily severe to the casual reader, he should not forget that the author is an enthusiast ; that he has given his life and energies to the sub- ject of the establishment of Veterinary Science in this country ; and that the evils so sev^erely combated are not " straw men," the creations of a vivid imagination, but actual evils that, unless prevented, will work most serious injury to the country in the not distant future. All that the author asks is calm reflection and an honest verdict upon his work. CONTENTS. PART I. PAGE The Diseases of Domestic Animals ...... 1 TrichiniasU of Man and Animals ...... 2 The Intestinal Trichinae . ..... 11 Trichiniasis in Swine ....... 15 Trichina; in American Pork . . . .18 Examinations of American Pork ...... 20 American llogs much more infected than European . . .26 The Di.-iease in Swine ....... 28 Prevention of Trichiniasis in Swine ...... 31 The Microscopic Examination of Pork ..... 32 Objects which may be mistaken for Trichinae, or not recognized as such . 34 Trichiniasis in Man ....... 36 Prevention of the Disease in Man ...... 40 Hog-Cholera . . . . . . . 41 Etiology . . . . . . . . .41 Bacillus suis ........ 43 Influence of Season and Temperature ...... 44 Incubation ......... 45 Pathological Anatomy ........ 47 Microscopic Observations ....... 48 Prevention of the Disease ....... 50 Disease of Cattle ...... .52 Tuberculosis in Cattle . . . . . . .61 Statistics as to its Prevalence . . . . . 71 Infection .......... 74 Bacteria ......... 79 Classification of Bacteria ....... 80 Distinction of Bacteria from Inorganic Objects .... 84 Dissemination of Bacteria in Different Media . .86 Nutrition of Bacteria ....... 86 Reproduction of Bacteria ....... 88 Reproduction by Spores ....... 89 The Action of Bacteria with reference to Contagious and Vinilcnt Disea.scs . 89 Dispersion of Bacteria and their Entrance into the Animal Organism 94 Infection of the Animal Organism ...... 98 Disinfection ........ 100 Vlll CONTENTS. The Diseases of Domestic Animals: Anthrax and Anthracoid Diseases History , . . . Etiology Nature of the Infectious Elements Appearance and Extension . Phenomena of the Disease Pathological Anatomy Prognosis Diagnosis Prevention Therapeutics . Immunity Anthrax in Man Etiology .... Symptoms and Course Therapeutics Anthracoid Diseases Emphysema infectiosum Texas Fever of Cattle . Definition Etiology Stages of the Disease Phenomena during Life Post-mortal Phenomena . Microscopic Examination Prophylaxis Diseases of the Dog Rabies Hydrophobia in France Phenomena of Canine Eabies Prevention Diseases of the Horse Glanders Transmission to other Animals Geographical Distribution Etiology . Tenacity of the Contagium . Natural Infection Disposition, Immunity Phenomenology . Duration of the Disease Acute Nasal Glanders Pulmonary or Chronic Glanders Pathological Anatomy Infiltrated Neoplasmatic Processes Diagnosis Prognosis Prevention Glanders in Man Cause . . . . Acute Glanders in Man Chronic Glanders in Man . CONTENTS. ix PART II. PAOK History of Veterinart Mepicink ...... 209 The Establishment or thk Veterinary Schools .... 2t)3 The Veterinarv Schools of Friince ...... 2G4 The Veterinary In-ititutc at Vienna ..... 280 Short Notiees of the Schools of Belgium, Sweden, Russia, and Norwny . 2'.)1 The Schools of Germany ....... 29!» Stuttgart ......... 2t'9 Ilanover ......... 30t Munich ......... 308 The Veterinary Institutions of Prussia ..... 321 The Prussian Laws for Suppression of Contagious Animal Diseases . .310 The Laws and Regulations for Rinderpest . . . . . 311 Special Regulations to prevent the Introduction of the Rinderpest from Foreign Countries . . . . . . . .34-3 Regulations with reference to Rinderpest in Germany . . . 344 Regulations to be put in force after the Rinderi)est has been declared ended ......... 347 Restrictions with reference to Use of Animals having Contagious Diseases 350 Anthrax ......... 851 Contagious Plcuro-pneumonia ...... 355 Glanders ......... 367 Variola of Sheep ........ 360 Rabies . . . " . . .362 Disinfectants ........ 864 PART III. The Means of Prevention ....... 368 A National Veterinary Police System ...... 368 The Foundation of Veterinary Schools in the United States . . . 390 State Veterinary School.^ . . . . . . . 415 A National Veterinarv Institute . . . . . . .419 IlYER^ri. :s££ooz r^ PART I. THE DISEASES OF DOMESTIC AK'BIALS. TuE subject of the relation of animal diseases to the public health, while not by any means unknown to hygienists, is still one whicli has not until the last few ycai"s attracted the scientific study which its importance demands. This is mainly due to the practical tendency which has prevailed in all veterinary schools, and which has been pushed, to the undue neglect of scientific investigation. Thankfully, the day of the school empiric is fast drawing to a close, and the rising sun of scientific research is beginning to dispel the fogs of tradition and the apathy of self-content which has rested upon veterinary medicine. The day has come when veterinary medicine is beginning to make its power felt, and to take its tnie place as a scientific institu- tion among the nations of the world. We have all been taught that the first commandment is "to have no other gods besides me." But without desiring to enter into the discussion of religious questions, the hygienist may say that, while this may be very important to the spiritual man, the earthy man has also certain positive responsibilities to himself, which find their expression in the command, " Man, know thyself." This commandment seems to be a stranger to the minds of most men, for how little do wo know of the physiological laws which control that complicated machine, the animal organism, or of the means by which we can in a large measure prevent diseases, not only among ourselves, but among our animals! The majority of our people assume that the nucleus of all knowledge is to be found somewhere in that record of Jewish history, the Christian Bible. "With reference to the prevention of human diseases from causes to be sought in the animal world, either directly or indirectly, we find, however, but little of practical value in that book. The in- 2 THE DISEASES OF DOMESTIC ANIMALS. structions of Moses to the Jews have far more to do with certain superstitions ideas of the cleanliness or uncleanliness of certain spe- cies of animals as unfitting them for food than with any true knowledge of their non-hygienic character. Enthusiastic but blind worshipers have even gone so far as to assert that Moses must have known that trichinae existed in pork, hence his forbidding its use as food. But they do not stop to think that these parasites require a microscope for their detection, an instrument which was not known to man until thousands of years after the books of Moses were writ- ten. That the flesh of diseased animals was unfit for human food did not entirely escape the attention of the Israelitic legislator ; but his restrictive utterances were limited to his own people. He tells the chosen of the Lord that : " Ye shall not eat of anything that dieth of itself ; thou shalt give it unto the stranger that is in thy gates, that he may eat it j or thou may est sell it unto an alien j for thou art an holy jpeojple unto the Lord thy GodP — See Deut. xiv, 21. Numerous passages, which command that all blood must be re- moved from the body before using it, lead us to infer that all such articles were to be well cooked before being eaten, and that raw or underdone meats were an abomination to the Jews, as they should be to all people. Plutarch asks : "Why is it that the priests of Jupiter are forbid- den to touch raw flesh ? " And answers : " Raw flesh is no more a living creation, and is unfit to eat. Cooking gives it another form." ]^ot only is human life endangered by the consumption of prod- ucts from previously diseased animals, or from the consumption of improperly cooked flesh, but quite a number of animal diseases are capable, by intentional or accidental means, of transmission to man. Yirchow has said that " man is far more susceptible to infection from animal diseases than the latter from similar diseases of man." TRICHINIASIS OF MAN AND ANIMALS. There is, perhaps, no one disease of our domestic animals which enjoys a more sensational reputation, or which has been more thor- oughly investigated, than the disease of swine caused by the parasite trichina spiralis. There is none more worthy of the attention of the public or the hygienist. Although the literature* treating upon * The American student will find the best compilation that exists on this subject in the " Report on Trichinge and Trichinosis," Glazier. 1881. Published by the United States Marine-Hospital Service. TRICniXIASIS OF MAN AND ANIMALS. 3 this disease is of comparatively modern date, still we have no justi- fiable reason for doubting the presence of these parasites in swine at a very early date, and also that the consecutive disease in man must have existed for years, if not centuries, before it came to sci- entific recognition; I am inclined to think, almost coeval with the consumption of pork as food. In this opinion I find myself op- posed by many distinguished observers ; but the fact that trichinae were not discovered earlier than 1831 does not at all militate against my conclusions. They simply were not suspected. Every fact in connection with the history of the parasite — its minuteness, the un- certainty of its pathognomonic phenomena in man, and still more so in the hog, which render ditticult the correct diagnosis of trichi- niasis — supports my hypothesis. Ililler* says: "The history of this disease can be appropriately divided into three periods, the first beginning with the discovery, or observation, of the capsule — the parasite not being recognized — in 1S21-'2S, including the description of the same by Dr. Hilton, of Guy's Hospital, London, England, in 1S35. '• The second period extends from 1835, when Paget discovered the encapsulated parasite and Owen described it, giving to it its name, 'trichina spiralis,' to the first authentic observation of the disease in a human being, and the direct establishment of its con- nection with a parasitic disease of swine which took place in 1860. " This begins the third period in the history of trichina spiralis — the period of active scientific investigation — which is by no means at an end, and which awaits its conclusion in the discovery of the original source whence swine derive the parasite." In the mean time, Professor Leidy, of Philadelphia, was the first to discover the parasite in the flesh of the hog in 1867. It is a singular fact that this discovery should have been made by means of an American hog. The principal workers in this important field of helminthic re- search have been Owen, Cobbold, Bristow, and others, in Britain ; and Leuckart, Virchow, Zenker, Kiichenmeister, and the veterinari- ans Gerlach and Fiirstenberg, in Germany. Cobbold t describes the parasite as follows : " Trichina sjnralis is an extremely minute nematode lielminth, the male in its fully de- veloped and sexually matured condition measuring only one eigh- teenth of an inch, while the perfectly developed female reaches a length of about one eighth ; body rounded and filiform, usually slightly bent on itself, rather thicker behind than in front, espe- * Ziem?3cn's " Encyclopscdia of Medicine," vol. iii. f " Entozoa," p. 335. 4: THE DISEASES OF DOMESTIC ANIMALS. cially in the males ; head narrow, finely pointed, unarmed, with a simple, central, minute oval aperture ; posterior extremity of the male furnished with a bilobed caudal appendage, the cloacal or anal aperture being situated between these divergent appendages ; penis consisting of a single spicule, cleft above, so as to assume a V-shaped outline ; female stouter than the male, bluntly rounded posteriorly, with genital outlet placed forward at about the end of the first fifth of the long diameter of the body. Eggs measuring y^w of an inch from pole to pole ; mode of reproduction viviparous." " The shell-less ova develop into minute embryos immediately on fructification, and completely fill the uterus of the female, and are born in immense numbers." * " The embryos measure, previous to birth, about ten micrometres in length, and five to six in transverse diameter. The study of the structure of the embryo is almost im- possible so long as it is retained within the body of the maternal parasite. Here it resembles a delicate thread, having a somewhat uniform granular appearance, which becomes less distinct as devel- opment progresses. In the older embryos — extra-maternal — we may perceive a very delicate cuticle and an axial line running through the body ; the extremities are more or less blunt, and not easily to be distinguished as to which is the posterior or anterior end of the parasite. In the intestines the embryos measure about 0*1 mm. in length, sometimes more, and have a transverse diameter of about 6 /i." (Pagenstecker.) " Within the abdominal cavity they may be found to measure from 0*12 to 0*16 mm. in length, with a transverse diameter of 8 fju. They have scarcely ever been seen less than 0"12 mm. in length when in the muscles. Comparison with mature trichinae indicates that the slenderer of the two extremities is the head." " The posterior extremity possesses more rigidity than the ante- rior, and also seems to have a backward and forward motion. The rigid condition of the terminal end of the parasitic embryo corre- sponds with the situation, or limits, of the axial line, which is looked upon as the rudimentary alimentary canal. The anterior portion of the embryo is not granulous, but clear, being only modified by a delicate chitin thread which is continuous with the cuticle, and con- stitutes the first indication of the chitinous lining of the oval cavity. As development progresses, this axial line divides into two parts ; the anterior portion corresponds to the so-called cell-body of the mature parasite, and the posterior to the stomach, intestines, etc. The sexual organs can not, as yet, be distinguished. The embryos * Leuckart, "Die menschlichen Parasiten," vol. ii, p. 512. TRICniNIASIS OF M.VN AND ANIMALS. 5 may be met with not only in the abdominal cavity of the autosite, but also in tlie thoracic and pericardial sac, and in such numbers that these places may be looked upon as normal resting-places for the embryos on their migrations ON'er the infected organism. In general we lind them far more numerously represented in the ab- dominal cavity, which corresponds exactly with our knowledge of their activity, for it is here that they must first come after passing the intestinal parietes on their migrations. From here they pass on to the other cavities b}' means of the natural openings, or ostia, through which the oesophagus and large vessels pass thi'ough the diaphragm. These vessels are loosely surrounded by connective tissue, which others favorable conditions for the passage of the para- sites. From these cavities the embryos follow the course of the larger vessels and nerves over the body, the loose connective tissue offering the favorable conditions. The duration of the migratory period can not be determined with any great degree of accuracy ; but it is undoubtedly very short, as embryos have been found in the thoracic cavity, the pericardial sac, and adjoining muscles, as early as in the abdomen. The majority of observer seem to agree in considering the ninth or tenth day of invasion as terminating the migratory period — that is, when but a single invasion has taken place." " The end)ryos display no distinguishable changes either in size or structure during the period of migration. The first appreciable changes occur after they have reached the muscles, and have be- come lodged in their fibers." " When they have penetrated the fiber — that is, become intra- sarcolemmatous — the protoplasma of the muscle-cell undergoes cer- tain pathological changes, which exactly correspond to the fatty de- generation observed in parenchymatous myositis. A proliferation of the nuclei is quite common, if not an invariable phenomenon. Like all tissues which have undergone fatty degeneration of their plasma, such fibci-s are darker, less refracting, than those which have not been subjected to parasitic invasion. Such fibers lose their con- tractility. When cut transvei*sely, the swollen jiarenchyma extends beyond the sarcolemmatous sheath, and if the trichina be near the section, it often extends free, or becomes free, with the protruded plasma. It is doubtful whether the triehinaj live upon the elements of the plasma while lodged in the fii)er, as they are in an appar- ently chrysalis condition. This fatty degeneration of the paren- chyma seems to offer no impediment to a second invasion of the fiber." 6 THE DISEASES OF DOMESTIC ANIMALS. " While previous to migration the embryo shows a somewhat slender form, it soon becomes thicker, or more rotund, its trans- verse diameter beiag nearly double that which it had before migra- tion. Its anterior portion becomes more slender and resembles that of the mature parasite. The posterior end becomes more blunt. Progressive changes also take place in the axial line, the different organs becoming distinct ; especially is this the case in the cell- body. The primitive sexual gland is to be seen as an elongated sac ; the pointed anterior end extends beyond the stomach in the females, and turns abruptly backward in the males. The oval cav- ity has a proportionate length, and over its middle distinctly shows the first traces of a nervous system, which in the form of an oval enlargement, cervical gangUon, is to be distinguished from the cy- lindrical mass." " With the progressive development of the internal organs comes a corresponding increase of the external dimensions of the parasite. It increases more in length than thickness, and its previous rotund form becomes more slender. At the same time the body becomes curved, and after a while assumes an irregular, spiral position — trichina spiralis. They begin to assume this position the earliest in the larger fibers ; but it occurs in all, even when the lumen scarcely exceeds the transverse diameter of the parasite. In the vicinity of the parasite the sarcolemmatous sheath invariably becomes dis- tended, owing to the lateral pressure exerted by the parasite. The spindle shape of the tube is due to the elasticity of the sarcolemma ; but, as it becomes thicker and clouded, proliferation must take place as well. The intra-sarcolemmatous, or capsular, development of the parasite terminates in about three weeks from the time of its in- vasion of the fiber." " The enlargements of the sarcolemma — capsules — vary much in form and size. Sometimes they are far more cylindrical and elongated than at others, and again one end may be elongated and the other bluntly rounded." " The capsules are surrounded by a rete of capillaries, which can be injected. A growth in length and thickness, due to the irrita- tion caused by the parasite, gives them a very ramified character." In this condition the parasites are known as " muscle trichinae " ; but when in the intestines of an autosite, as " intestinal trichinae." In the first form they make their abode entirely in the striated, or motory, muscles — the flesh. They have not been met with in an encapsulated condition, either in the non-striated muscles or in purely adipose tissue. TRICmNIASIS OF MAN AND ANIMALS. 7 "While this seems to be tlie opinion of almost all observers, durin<^ my observations in 1879, and again in ISSl, I frequently found encupsuled trichiniii in the midsit of purely adipose tissue, hetween muscle-Jibers of very fat hogs ; iiever^ however, in the adi- pose tissue which lies upon musculature. Since then, other observ- ers have rei^orted the same thing. In a letter, read at the ninth annual meeting of the American Public Health Association, held at Savannah, Georgia, in 1881, emanating from the Department of Agriculture, dated October 20, 1881, the author, with the custom- ary ignorance and consequent impudence of an American politician, says, in answer to the question, " Are trichintii found in the fat ? " " I have until now thought not. Professor Taylor, of this depart- ment, tells me that in the ' Journal of the Microscopical Associa- tion' he has recently seen that they have heen found in fat. I should rather see than believe without so doing.''^ I think this is easily explained. The great amount of fatty in- filtration had caused absorption of the plasma, and atrophy of the fibers by compression, which was, however, resisted by the greater density of the sarcolemma in the vicinity of the parasite, and also by the latter itself. Xo other explanation seems to me possible, for the capsules were comparatively perfect. The encapsuled parasites may be met with in the striated mus- cles of all parts of the body, such as the digital muscles, those of the abdominal walls, of the extremities, the eye, the ear, the larynx and pharynx, the tongue, oesophagus, and the diaphragm ; but the heart seems to be a favored locality, for they have only been found in its flesh in very isolated cases. In making examinations of the CBsophageal muscles of a rabbit that had been fed with infected pork, I was much struck "with the abruptness with which I met trichinse, in passing in review a mi- croscopical section of the oesophageo-cardiac portion of the stomach, when one passed from the fibers ])roper to the stomach to those of the oesophagus ; in fact, trichinae could be seen in the striated fibers of the latter, where they intruded between the non-striated of the former ; but in no case were there any to be seen in the smooth, or inorganic fibers. These parasites are not, however, equally distributed over the musculature of the autosite, but, on the contrary, appear to have their favorite places of abode. They have a predilection for the muscles of the anterior part of the body; of these, those of the tongue, larynx and pharynx, and masticator}* muscles are especially favored. The muscles of the rump are more profusely invaded 8 THE DISEASES OF DOMESTIC ANIMALS. than those of the extremities. Very few have been discovered in the tail of any animal. In the extremities, the parasites are found to be more abundant where the muscle-fibers begin to lose them- selves in their tendinous extension than in the body of the muscle. ]^umerous estimates have been published by different observers as to the percental invasion of the different muscle-groups, several of which may be given here. Microscopic specimens,* of an average length of two centimetres and a width of one centimetre, were taken from the flesh of several hogs which had been found triehinous. Eighty sjDecimeus taken from hog 'No. 1 gave the following : a. Pillars of diaphragm 12 trichinse. &. Muscles " 4 " c. " larynx. 1 " d. " ribs None. e. " tongue " /. " neck " g. " eye and overarm " Sixty specimens from hog Ko. 2 : a. Pillars of diaphragm 10 trichinaB. &. Muscles " 6 c. " larynx 2 " d. " ribs None. e. " tongue " / " eye '" g. " overarm and neck " Forty from hog 'No. 3 : a. Pillars of diaphragm 40 trichinse. &. Muscles " 25 c. " larynx 4 " d. " ribs 6 " e. " tongue 8 " /. " neck, eye, and overarm 2 " Forty from hog No. 4 : a. Pillars of diaphragm 40 trichinse. h. Muscles " 30 " c. " larynx 10 " d. " ribs 10 e. " tongue 6 " /. " overarm -. 2 " * " Mittheilungen aus. d. thierarzlichen Praxis im Preussischen Staate," 18V7-"78, p. 99. TRICHINIASIS OF MAN AND ANIMALS. 9 According to Gerlach : * One jj:raiii of flesh taken from tlio Psoas luuscle coutuiued IGl tricluuo). Diaphragm muscle . " 129 '' Laryngeal " " 120 " Tongue " " 105 " Orbital " " C4 Abdominal " " 54 " Mas.-^etor " " 45 " Lips, near snout '• 43 " Serratus magnns " 39 " Pectoralis major " 33 " CEsophagus, anterior to the diaphragm " 31 " " posterior " " 1 " Pelvi-femoral muscle " 20 '' Tibial " " 26 " Longissimus-dorsi muscle " 20 " Soapulo-humeral " " 18 " Radio-ulnar " " 17 " Metatarsal " " 9 " Intercostal " " 8 " Small muscle of ear " 2 " " tail " 1 " Kriimerf gives the following as the results of examining one gramme of tiesh from different parts : From the biceps contained 420 trichina). " raasseter " 213 " " genio-glossus " 188 " " gastrocnemius " 186 " " sterno-mastoid " 171 " " pectoral " 148 " '• diapliragm " 129 " " crico-tliyroid " 124 " " intercostal " 113 " " rectus abdominis " lOO " '* psoas " 105 " " tongue " 58 " " laryngeal " 21 Not having any opportunity to make detailed examinations of the muscles of any whole or single hog, I could not make any per- sonal observations of the percental di^-jK^i'sion of the trichinae over the different muscle-groups or parts of the organism. Coming upon a piece of a pillar of the diaphragm which was wonderfully infected, I made the following numerical observation * " Die Trichinon." f " Deutsche Klinik," July and August, 1872. 10 THE DISEASES OF DOMESTIC ANIMALS. (in fact, I never saw among all my examinations a piece of pork so completely filled with these pests ; capsules with four trichinae in them were by no means seldom) : '05 (5 centigrammes) contained at least 50 trichinag. One gramme would therefore contain 1,000, and 4 grammes, or a drachm, 4,000, and a pound of such pork would contain at least 400,000, and, if we assume the muscles of a hog to weigh 100 pounds, its organism — were equal dispersion pos- sible—would contain 40,000,000. The immense multitude of these parasites which may be found infecting a sing-le oro^anism is still more wonderful than their wide O C5 O dispersion over the autosite. Leuckart estimates that, in some of the cases which have come under his observation, a single gramme of flesh lodged from twelve to fifteen hundred ; and assuming the muscles of a man to weigh forty j)ounds, the number of these parasites infecting a human or- ganism at such a ratio would sum up some thirty millions. In Zenker's case — to be especially noticed later — Fiedler calcu- lated that the woman must have lodged some ninety-four millions ; and Cobbold assumes that one hundred millions of the encapsulated parasites may sometimes infect one organism at the same time. Leuckart again says that no one would look upon the foregoing as exaggerated estimates who, like himself, had found some sixty trichinse in ten milligrammes of muscle. In a report of the Chicago Academy of Sciences, it was esti- mated that one cubic inch of pork, examined under its auspices, contained some ten thousand, and that a person consuming the ordinary amount of such fiesh, taken at a single meal, would intro- duce into his organism more than one million trichinae. Kauch found numerous trichinae infecting the muscles of a hog. Of three hundred microscopic specimens, they failed in but tliree. In some he found thirty in one focus ; in others, but five or six ex- amples. As in seventy specimens weighing one gramme three hun- dred and fifty trichinae were found, one pound would contain one hundred and seventy-five thousand ; and one hundred pounds, sev- enteen million five hundred thousand. In many cases, however, the parasites are much less frequently met with ; and one has to search through many microscopic specimens before meeting with any, and then only with isolated examples. "When sufficient time has elapsed from the invasion of the mus- cles and formation of the capsules, the same may be recognized microscopically as small, white specks. Such muscles appear as if sprinkled with grains of white salt or sand. The calcification of TRICniXIASIS OF M-VX AND ANIMALS. H the capsule begins about the fifth month subsequent to the invasion of the muscles. It lias been said by some observers that the trichinae capsules in the hog do not calcify ; others aflSrm the contrary. The polari- scope, liowever, will reveal tlie presence of calcareous salts in the capsule if sutHcicnt time has elaj)sed since invasion. The reason they may not be easily recognized microscopically must be souglit intlie influence on the salts of the fatty oils in the porcine organism, which renders the crystals less visible. The Intestinal Tkichinje. So long as the trichinjB remain encapsulated in the fibers of the muscle, their condition remains unchanged. They make no progress in their development, irrespective of the number of years that they may have been imprisoned. They have been seen in an active — i. e., capable of progressive — development, under favorable conditions, thirteen, twenty, and even twenty-four years from the time invasion took place. a. In 1861 a woman was admitted into the hospital at Altona, Ger- many, suffering from a mammary cancer, which had been develop- ing some twelve years. On its removal and subjection of its tissues to microscopic examination, the presence of trichinje in the muscle- fibers was manifested. On inquiry, it was ascertained that in 1856 the woman had resided at Davenport, Iowa, where she was taken suddenly very ill, gastric and rheumatic phenomena being the most prominent of any, together with oedema of various parts and para- lytic phenomena. Her brother, with whom she resided, was at- tacked in a similar but less severe form at the same time. The woman died at the Altona Hospital in 1864, and an examination of lier muscles revealed the presence of great numbers of encapsulated trichinae. A cat fed with pieces of these muscles died in the course of sixteen days, its muscles being repletely infected with these parasites. h. Virchow reports a case where, after the lapse of thirteen years and a half the parasites moved in their capsules on prolonged ex- posure to the heat of the sun. c. Klopsch reports a case of trichiniasis, with complete recovery, which took place in 1842. The parasites were discovered in the muscles of the individual twenty-four years afterward. This dis- covery was also made on the excision of a mammary cancer. At the same time that this woman was ill, two persons in the same house became sick under similar conditions. Both died. (Virchow's " Archiv," Bd. 35, p. 609.) 12 THE DISEASES OF DOMESTIC ANIMALS. d. Professor Dammau,* formerly of the Elclena Agricultural Academy, reports a very interesting case, illustrating the longevity and tenacity of life of embryonal tricliinse in the muscles of a hog. This hog was fed with trichinous meat in November, 1S6J:, and in February, 1865, presented to the experiment station at Eldena. Since that time the animal had been kept isolated, unless removed from its pen for examination. On February 3, 1875, and February 12, 1876, Dammau removed a small piece of flesh from the shoulder. At both times trichinae were found. A considerable piece of flesh was removed and fed to two rabbits, and eighteen days subse- quently their muscles were found to be j)lentifully invaded with trichinse. This case demonstrates, beyond all question, the presence of living trichinse, which were caj)able of maturing, fructifying, and developing young when fed to other animals, after a period of eleven years and a quarter from the time that the invasion of the hog took place. Although the encapsulated trichinse suffer no changes while confined in the muscles of an autositic organism, yet the introduc- tion of portions of such muscles into the intestinal tract of man, or other suitable animal, causes rapid changes in their condition. The processes of digestion soon set the imprisoned parasites free from their capsules, three to four hours being sufficient for the purpose. The freed parasites rapidly complete their development to mature trichinae, thirty to forty hours being enough. In cases of fresh in- vasion, when the capsules have not become very hardened, twenty- four hours have been found sufficient to demonstrate the presence of sexually matured trichinae in the intestines of animals fed with such flesh by way of experiment. Still, we may often find trichinae inclosed in their capsules on the third day after feeding infected flesh to an animal. There is scarcely another helminth by which this matured stage in its development is reached in so short a period. Under these circumstances it is self-evident that the changes necessary to maturity by these parasites must be of a very insignifi- cant character. As a rule, sexual connection takes place within two days from the time the trichinae become free. The parasite increases in length and thickness, and in the fe- male the uterus fills with fructified ova, which soon develop into embryos still inclosed in the maternal worm. * "Zeitschrift fiir prac. Thi«rlieilkundc," ISYG, vol. iii, p. 92. TRICHINIASIS OF MAN AND ANIMALS. 13 The female intestinal or matured parasite lives from five to six weekr;, and produces at least fifteen Imndred embryos. (Leuckart.) The newly burn embryos are at first buried in the mucus which lines the intestinal canal ; a microscopic examination of such mucus, at this time, will reveal them as free and niovaldc parasites. The embryos soon begin their migration and dispei*si(.)n over the organ- ism, the first act being the penetration of the intestinal parietes. It seems to be still a matter of discussion as to the means or ways by which further migration takes place. Some authorities, in fact, all the most eminent, favor the view that the parasites proceed by the way of the mesenterium and connective-tissue tracts over the or- ganism, and penetrate the sarcolemma, or sheath of the muscle-fibers. Another view, the possibility of which is conceded by the above-named authors to a minor degree, is that the embryos gain access to tlie circidation, and are transported over the organism by the moving fluid, boring the smaller vessels at convenience, and thus gaining access to the muscles. (Thudicum.) AVere this the principal j^ath of dispersion, we ought to be able to discover numerous examples of the parasite in the circulating blood of living animals that have been subjected to feeding experi- ments. This has not been the case, however. Thxis it is evident that the host, or consumer of trichin-infected Jit sh, provides the means for its own invasion. While this is, in general, the manner in which invasion takes place, it by no means excludes the possibility of the infection of an animal taking place by intestinal trichinas (embryos), which have passed from an already infected organism with its fieces. In this way an infected swine may infect others, or, in fact, give occasion to a secondary invasion of itself, by rooting in the manure of its j^n. In the same way swine may become infected from infected human beings where, as is too often the case, the out-houses for the family are placed over the pig-pen, or load into it, or where the contents of the same are thrown into the piggery for the swine to work over. Thus we see the cycle of invasion may frequently continue from swine to man, and from man to swine. Trichinre may be assumed to be regidar cosmopolitans. AVhethor Xoah took a pair of them with him into the ark will probably con- tinue to be an open question. They have been discovered in Ger- many, England, Scotland, Denmark, Sweden, Kussia, France, Italy, North and South America, Africa, India, Australia, Spain, Egypt, and Syria. 14 THE DISEASES OF DOMESTIC AXIMALS. In fact, it may truly be said that they have been found infecting pork in whatever land, and wherever they have been sought for. As to their presence in other animals than man and the hog, they have only been unquestionably found in warm-blooded ani- mals, such as cats, dogs, rabbits, rats, mice, the marmot, the wild hog of EurojDC, and even the hippopotamus. Gerlach has produced invasion in calves and horses, while Leisering was unable to in the latter animal. Several reports have been published with reference to the dis- covery of trichinae in the flesh of fish and other cold-blooded ani- mals, but they all fail of experimental proof, and are non-conforma- ble with our knowledge of the physiological activities of the parasite, which becomes torpid in a temperature a few degrees below that of the ordinary living mammal. For some unknown reason they do not seem to be able to invade the muscles of fowls, though some authors claim to have found them in the intestines. A case is reported of invasion of some soldiers from eating a goose ("Philadelphia Medical -Times," April 13, 1878), the accuracy of which is very questionable, as pigs are fully as easily stolen as geese; and no evidence exists that they were seen in the flesh of the goose. "With regard to hens, I made quite a series of experiments. 1. I fed them with highly infected pork, in the natural way. Results negative. 'No trichinae, either in the intestines or mus- cles. 2. Assuming that the triturating powers of the gizzard might be sufficient to destroy the parasites before they could gain access to the intestines, I caused a quantity of infected pork to be chopped for several hours, until it became a veritable mush ; microscopic examination of this mass revealed the presence of numerous free trichinge. This mass was stirred up with warm water, so that it could be drawn into a coarse syringe ; the intestines of the fowls were then washed out as cleanly as possible with warm enemas, and time given for the water to flow off again. Several syringefuls of the mass were then injected, and the outflow stopped artificially. After forty-eight hours this obstruction was removed. Results absolutely negative, so far as producing muscle-invasion was con- cerned, at an examination made four weeks from the time of the experiment. No trichinae in intestines. 3. The abdominal cavity of six other fowls was opened, and two tablespoonfuls of the watery mass, but thicker than the preceding, poured in. The aperture was then sewed up. The hens drooped TRICniNIASIS OF MAN AND ANIMALS. 15 a few days, but recovered, and ate well. Examination at the same time with the othei-s gave negative results, altliough a queer-looking condition of tlie abdominal cavity existed. Why these hens did not die of septictemia I do not know. I had hoped to carry on numerous feeding and therapeutic ex- periments during my examinations of i)ork in 1S81, but lack of means on my own part, as well as on the part of the Board of Health of Massachusetts, prevented their accomplishment. Tricudoasis in Swine. As we have previously mentioned, the disease was discovered in swine by Leidy, in 1847. It is to German observers that we must look almost entirely for any authoritative statements with reference to the percental infection of swine with these pests, for in no other country is there at present anything approaching a systematic examination of pork, and even in Germany there is much room for improvement. To make the statistics valuable, it is necessary that the law should require that, at least so far as domestic consumption goes, all hogs should be examined before being cut up, and that only one part — viz., the pillars of the diaphragm, or psoas muscles — slioiild be used for examination. There is no evidence that this is the case in Germany, hence I much doubt whether it would not be possible to largely increase their present ratio of infection. The following statistics have been gathered at random, M'ith no attempt at com- pleteness, but simply as illustrations, from the books in my own library, such as Virchow's " Archiv," the " Yierteljahrsschrift f iir gerichtliche Medicin," the " Deutsche Zcitschrift fiir Thiermedicin," "The Veterinary Reports of Saxony and Hanover," the " ^lagazin fiir Thierheilkunde " (Gurlt u. Hertwig), the " Archiv fiir Tliier- heilkunde," and the " Mittheilungen aus d. Praxis d. Preussischen Staate." For Rostock, Germany, Petri gives the following : 1869 Number hogs examined, 5,4o7 ; trichinons, 1 1871 " " " G,520 " 2 1872 " " " 6.555 " 0 1873 " " " 0,441 " 3 1874 " " «• fi,731 " 2 1875 " '> '• 7,222 " 5 1876 " " '• 7.165 " 0 1877 " " '• T,5G2 " 2 Total 53,653 15 Tricbinou.-=, 1-3543. 16 THE DISEASES OF DOMESTIC ANIMALS. For Braunschweig, Ulide reports : Whole number examined between 1866 and 1880, 111,806 ; trichinous, 29. 1866-'67 there was found 1 liog of every 6,700 examined, trichinous. 1867-'68 ' ' 5,700 1868-'69 ' ' 14,500 1869-'70 ' ' 15,300 1871-'72 ' ' 13,387 1872-'73 ' 4,874 1873-'74 ' 5,129 1874-'75 ' ' 7,004 1875-'76 ' 13,183 1876-'77 ' 7,127 1877-'78 5,879 1878-'79 ' 10,397 1879-'80 3,857 PRUSSIAN STATE STATISTICS. No. examined. Trichinous. Measles. No. of state examiners. 1876 1,728,595 2,057,272 2,524,105 3,164,656 3,342,303 800 701 1,222 1,938 2,284 4,705 5,434 6,165 9,669 11,379 11,915 1877 12,865 1878 16,251 1879 17,413 18,332 1880 Total 12,816,831 6,945 Trichinous, 1 to 1,845. Eulenburg's report for 1880 deserves some special consideration. The ratio of trichinae in swine in Prussia has, we see, constantly advanced with each year since 1876. In 1879 it was 1 to 1,632 ; and in 1880, 1 to 1,460 ; which must be attributed to greater exact- ness in the observations. The great number, constantly increasing, of appointed examiners is also worthy of notice: from 11,915 in 1876, they have been increased to 18,332 in 1880. In Berlin they found 1 to 1,247 swine trichinous, while in Posen the ratio was 1 to 138, which more nearly corresponds to the conditions in this country. There does not seem to be &t present any endeavor on the part of the Government to make investigations into the cause of these things. Three hundred and twenty-nine cases of trichiniasis among human beings, and four deaths, are reported. In all cases it was traced to the consumption of either uncooked or improperly examined pork. In Berlin there were but sixteen cases during the year, a much smaller number than in previous years, which is at- tributed to the greater stringency with which the examinations are carried out. One of these cases is interesting from the fact that TRICniNIASIS OF MAX AND AXIMALS. 17 the person who died, consumed, raw, a piece of pork known to he trichinous, in order to show tl»at the idea that trichinsij caused dis- ease in man was a faUacy. Of examinations of American pork, the report says 3,030 trichinous pieces, sides, were found. Such an examination lias no statistical value, as it does not show whether the sides were all from different hogs or not ; further, were they all American I The average of trichiniasis in American I'Ieces, not hogs, was found to be 4 to 100. It was found that the abdominal muscles were only serviceable for examination, or such as were at- tached to the shoulders. More than twenty sides a day should not be examined by one person (?). In Schleswig, of TS2 " Amerikanischen Rouladen," 8 were found trichinous ; of 1,052 sides, G4 ; 3,903 hams, 6G ; and 13 shouldei-s, 3. In Stettin, of 72,230 sides, 1,124 were found trichinous. The number of swine affected with measles was 1,710 more than in the former year. From Hamburg, Germany, we have a few statistics which may have an instructive comparative value : In 1ST8, of 35,510 American hiiins esaininod, 397 trichinous. '' " 14,003 " Bides " 85 " 17,113 European haras " 3 " " " 2'2-2 " sides and 10,838 hogs examined, none trichinous. In 1879, of 79,8G4 American hams exnmiued, 1,087 trichinous. 41 (( 22,749 " sides and shoulders examined, 196 trichinous. '' " 28,710 European hams examined, 2 trichinous. " 16,204 " hogs " 1 " In 1880, of 55,008 American hams examined, 566 trichinous. " " 23,589 " sides " 270 " " " 49,943 European hams, sides, and hogs examined, none trichinous. At Blankenburg, from 1864-'65, 7,000 to 8,000 hogs examined, and but 1 in- fected. At IXanorer, from 1865-'66, 18,656 hogs examined, and 12 trichinous. In Sachsen-Weimar, from March, 1868-'69, 19,611 examined, and 1 found trichinous. In 1875-'76, at Frankfort, 8,000 hogs examined, 4 tricliinous. " " Gulen, 1,600 to 1,800 hogs examined, 1 trichinous. At Copenhagen, 1867, 8.174 examined, 15 trichinous. At Charkow, Russia, 1876, 3,550 examined, 5 trichinous. These statistics could be multiplied ad libiiu)n, but they are sufficient to show the results of Continental examinations. It is to be regretted, however, that we have no reliable statistics from either England, Scotland, Ireland, or France, or other Continental coun- tries, since they have commenced to lay so much stress upon the infected condition of American pork. 2 18 THE DISEASES OF DOMESTIC AXIMALS. Trichina in Americajst Pork. "We have already noticed the examinations of American pork made at Hamburg during several years, and will follow with a few more quotations of the same nature : At Rostock, 12 of 622 Americaa sides were found trichinous. At Gothenburg, 8 of 210 American sides were found trichinous. At Ebbing, 2 per cent of the pieces examined were found trichinous. In Schleswig-Holstein, of 5,673 pieces examined, 47 were found trichinous. In 1877, 343 cases of infected American pork were reported, and 183 cases of the disease in human beings. In the early part of the year 1881, badly infected American pork was reported as having been found at Lyons, France. Professor Mueller, of the Berlin Veterinary Institute, wrote me, under date of December, 1880, that of eighty-eight live American hogs (constituting a part of a shipment) that had been slaughtered at Dresden, fourteen were found trichinous. Dr. Loring * says, " I do not know that Germany or France has even examined for this disease in live hogsP The foregoing was reported by me in American papers at the time, and subsequently in the report of the Imperial Board of Health of Germany, and several German medical reviews ; and could have been as well known to our agncultural department as the presence of pleuro-pneumonia in the District of Columbia, a fact that ocular demonstration of diseased lungs could scarcely force upon our agricultural commissioner. At Turin, Italy, February, 1879, four per cent of a lot of Cin- cinnati hams were found trichinous, which led to the Government putting restrictive examinations on all further importations. A continual recurrence of such facts has caused a more or less strong feeling on the Continent against our pork, a feeling which nationalism and the public prints have fostered to the fullest extent. The result has been that in many countries restrictive measures regulating the importation of American pork have been introduced, which to a certain measure have acted as an embargo against further importations. In some countries these measures have even been extended to American lard, and a great alarm created about some kind of hydraulic pressing out of the same instead of trying it out ; in fact, everything possible is being done to keep out the competi- tion of American products. * Letter to Health Congress, Savannah, 1881. TRICniXIASIS OF MAX AND AXIM.VLS. 19 "With regard tt.) our pork, I think the assertions of tlie Germans and their restrictive measures are just. Naturally enough the old adage, " Touch a man's pocket and you touch his heart,'' found an illustration on this side of the Atlantic. The pork-producers of every variety became very much alarmed, and called upon the Government to assist them. Our consuls all over Europe were requested to make inquiries as to the true nature of these reports, and to report to their own Government. It is not within the nature of my work to consider these re2:>orts in detail ; but, suffice it to say that they displayed fully as much patriotism for the purity of American pork as the Continentals did for their o^^^l. Some went so far as to call the whole thing a humbug. A real desire to know the truth pervaded neither our representatives at home nor abroad. As with pleuro-pncumonia of our cattle, so with trichiniasis of the hog, our Government adopted a prevaricating and false course. It sought to "bluff down" the results of foreign examinations, and either did not seek to discover, or ignored the results of, home ex- aminations. In the face of a report of the State Board of Health of Massa- chusetts— numerous copies of which were sent to Washington — which contained a pa])er on the subject of trichiniasis, and statistics of the examination of the largest number of hogs which had until then been made in the country, the State Department published a singular document, which requires attention. It utterly ignored the statistics of the above report. Clauses 8, 9, and 10 are as follows : 8. That the percentage of American hogs infected with trichinaa is, in all prohabililt/, hy reason of tJie superiority of the hreed (which?) and feeding, much less than that among the hoys of any other country. 9. That freedom from trichiniasis of the two great pork-consuni- ing centers of the West, Chicago and Cincinnati, furnishes the strongest possible evidence of the purity of American ])ork. In Chicago, of forty thousand deaths, with causes, reported for a series of years, oidy two were from trichiniasis. During the same time none were reported in Cincinnati. 10. The reported cases of trichiniasis among human beings have resulted from eating uncooked pork, etc. With regard to trichiuie in American hogs, the above-quoted sections from a state document have no foundation whatever. They have nothing to stand upon. 20 THE DISEASES OF DOMESTIC ANIilALS. In clause 8 it does not stand upon facts, but upon a mere asser- tion— that "probably," etc. Again, the person who instructed the Government knew abso- lutely nothing about trichinse. Neither the breed of the hogs nor corn-feeding, or any manner of feeding as commonly practiced, aside from swill-feeding, need have anything to do, ])ro or con^ with tri- chinse in the hog. The hogs at the two great packing centers have never been thoroughly examined for trichinse, and at the time this document was published neither the Interior nor any other depart- ment had organized any proper examination of American pork. The j)ercentage of deaths among human beings has nothing to do with the percentage of infection among swine. Luckily for the American people, it has not. Even though cooking will kill trichinse, and thus render infected pork harmless, it does not prove that American hogs have " much less trichinse than those of any other country." A German has as much right to indulge a taste for uncooked smoked ham or spiced hashed pork as an American or Englishman has for rare or raw, warm or cold roast beef. The German may be invaded by trichinse for his cannibal- ism, and the American by a tape-worm {icBnia 7nedio-candlata). Examinations of American Pokk. At Chicago, April, 1881, a Dr. Paton is said (newspaper report) to have examined twenty specimens each, from four hundred hogs, and found none trichinous. The Chicago Academy of Sciences (" Boston Medical and Surgi- cal Journal," vol. Ixxiv, p. 136) reports the examination of thirteen hundred and ninety-four hogs, and finding twenty-eight trichinous. Health Commissioner De "Wolff reported (1879) finding eight out of a hundred trichinous. In 1879 I commenced my examinations of pork for the State Board of Health of Massachusetts, and again during three months of the summer of 1881. These examinations were not made upon any selected lots of swine, but the specimens were taken at random from the hogs as they hung up. 1^0 attempt was made to discover whence the hogs originally came, though, with the exception of about fifty, they were all bought at Chicago, and hence %cere emphatically Western hogs. In making these examinations, the pillars of the diaphragm were inva- riably used, one piUar representing one hog. But three microscopic specimens were taken from each pillar — a rule which I invariably adhered to. TRICniNIASIS OF MAX AND ANIMALS. 21 1879. LOT. 1 2 3 4 5 6 7 8 9 10 11 12 l:} U 15 \6 17 IS 19 20 Number ex- auiluud. 47 48 72 fio 226 11)2 100 81 95 93 98 300 201 192 200 257 2:]8 163 26 12 2,701 Non-infoctod. Trlchioous. 44 3 46 2 62 10 r,G 4 210 16 179 13 96 4 80 1 94 1 89 4 90 8 275 25 188 13 187 5 184 16 252 5 225 13 154 9 25 1 11 1 2,547 154 Trichinous, 1 to 17'54. From the same source as tlie preceding : 1881. LOT. Number ex- amined. ' Non-infected. Trichinous. 1 127 130 153 1 120 127 15(1 7 2 3 3 3 4 120 115 5 124 KiO 123 ' 99 1 6 1 7 119 127 113 123 6 8 4 9 1 60 152 8 10 125 lis 7 11 127 122 5 12 122 118 4 13 124 KiO 122 118 100 115 6 14 0 15 7 16 120 114 6 2,000 1,929 71 Trichinous, 1 to 28. 22 THE DISEASES OF DOMESTIC ANIMALS. rrom another source : LOT. Number ex- amined. Non-infected. Trichinous. 1 129 130 140 105 73 130 119 127 132 182 93 128 112 124 81 84 120 59 120 123 130 102 71 125 115 120 130 175 93 125 110 120 80 80 117 57 9 2 7 3 10 4 3 5 2 6 5 7 4 8 7 9 2 10 7 11 12 3 13 2 14 4 15 1 16 4 17 3 18 2 2,008 2,199 75 Trichinous, 1 to 27. From a third source : LOT. Number ex- amined. Non-infected. Trichinous. 1 105 45 65 80 61 63 96 100 100 98 90 101 121 103 76 102 130 130 131 122 85 105 45 64 78 60 60 92 99 99 96 86 98 121 100 75 100 124 125 128 120 84 2 3 1 4 2 5 1 6 3 7 4 8 1 9 1 10 2 11 4 12 3 13 14 3 15 1 16 2 17 6 18 5 19 3 20 2 21 1 2,004 1,959 45 Trichinous, 1 to 44. TRICHINIASIS OF MAX AND ANIMALS. 23 KE8UME. Number of hogs exaiiilned. Non-infoctcd. Trichlnous. 1879 2,701 2,000 2,UG8 2,004 154 71 75 45 1 to 17 1881. Same source 1 to 28 " Seeoiul source 1 to 27 *' Tliires, but by no means as convenient as the Ilartnach model of Continental makei*s, are to be had from Americans at from fifteen to twenty dollars. A large table to the microscope is a con- venience. A few glass slides, or object-glasses, and some strong covering- glasses, a pair of small curved scissors, and two teasing-needles, are all that is necessary to complete the outfit. The first step is to take a piece of muscle and cut into its sub- stance, in order to have it as moist as possible, and with the curved scissors cut several thin slices lengthwise to the fil)ers, and with a needle place them on the object-glass a little distance apart; the ,rf'f.'':Cit/' • ' rr/r ■■ I Fio. Fio. 1. — Fresh Trichinous Invasion. ^Leuckan.; covering-glass is then to be placed upon them and gently pressed with a slight, rolling motion, which will invariably make the speci- mens thin enough for examination. 3 34: THE DISEASES OF DOMESTIC ANIMALS. It is not necessary to cleanse the glasses for each specimen to be examined. To determine if the trichinae still live, place the object-glass over heat — a spirit-lamp — for a second, enough to warm the slide, and then place it under the microscope, and they will be seen to move in their ca^^sules. Salted pork is best examined by cutting it into thin pieces and soaking for a time, although the specimens can be at once placed in water for a few moments. Objects which may be mistaken fob Tkichin^, or not eecog- nized as such. It not unfrequently happens that the capsules become abnor- mally thickened, and the parasites dead within them. They do not then present the same appearances that are generally observed under normal conditions. Fig. 3. — Encapsuled Concretions WITH Dead Embryos in them. Fig. 4. — Trichina -Capsules with Calcified and Disintegrated Con- tents. In other cases the calcification is of such a character as to almost entirely change the appearance of both capsule and contents. Treatment of such capsules with hydrochloric acid will render the diagnosis easier. TRICUIXUSIS OF MAX AXD ANIMALS. 35 In some cases cysticerci, measles, perish and become calcified. These objects are somewhat larger than trichina-capsules, and often contain a caseous mass. The sacs of Raiuey, or, as they are also termed, " psorospermije," are elono^ated granulous bodies, like the triehime, situated wii/nn the sarcolemnia of the liber. Their true nature or pathological im- portance is not yet well determined. Some valuable diagnostic points are, that in the latter — i '^ . , " ' ' ^r) trichinai — the striation of the fiber is entirely destroyed with- in the capsule, while by i)soro- sperms it is retained, limiting the objects laterally, and con- ' tinning directly from their ex- tremities. Bruch,Virchow, and Leuck- art have described peculiar ,. r r. n - xr _ ■» iio. 5. — rreservation of the poison in infected pens and yards, alike in winter and in summer, to say, nothing of its possible conveyance by means of fodder or other vehicles." Incubation. According to the average drawn from a large number of obser- vations, the period of incubation varies from five to fifteen days. Intka-vttal Phenomena. One of the very earliest symptoms is a marked rise in the tem- jx'rature of the hog ; yet the fact is not without some questionable diagnostic value : first, on account of the variations which seem to exist in the normal temperature of different hogs ; and, second, the difficulty which the struggle of the pig throws in the way of the proper application of the thermometer, which may in some cases cause a more or less marked rise in the temperature. Detmers does not consider the thennometer of any great value in the diagnosis or prognosis of this disease. The disease frequently announces it- self by a cold shivering on the ])art of the atfiicted swine, lasting from a few moments to several hours, frequent sneezing, and more or less coughing. These anticipatory symptoms are soon followed liy a more or less loss of appetite, a rough and somewhat staring condition of the bristles, a drooping of the ears, loss of vivacity, and in some cases by vomitiTig ; a desire to bury themselves in the bedding and to lie down in dark and quiet corners; a dull and injected condition of 46 THE DISEASES OF DOMESTIC ANIMALS. the eyes ; swelling of the head, eruptions upon the ears and other parts of the body ; occasionally bleeding from the nose, and partial or total blindness ; dizziness, diarrhoea, and stertorous breathing. The flanks fall in, and the animals rapidly become emaciated, and betray a vitiated appetite for dung, dirt, and saline substances ; in- creased thirst, accumulation of secretions in the canthi of the eyes, and more or less copious nasal discharges. The peculiar offensive and fetid smell of the exhalations and excrements may be looked upon as characteristics of this disease. This odor is so penetrating as to announce the presence of the disease, especially if the herd of swine be a large one, at a distance of half a mile, or even more, if the direction of the wind be favorable. If the animals are inclined to be costive, the faeces are generally grayish or brownish-black in color, and hard ; if diarrhoea is present, they are semi-fluid, of a grayish-green color, and in some cases contain an admixture of blood. In a large number of cases the more tender portions of the skin on the lower surface of the body, between the posterior ex- tremities, behind the ears, or even on the nose and neck, exhibit numerous larger or smaller red spots, or sometimes a uniform red- ness. Toward the fatal termination, this redness frequently changes to a purple color. The physical examination of the thorax reveals, if pleuritis be present, the characteristic crepitation. As the patholog- ical processes progress, the movements of the afflicted animal become weaker and slower, the gait staggering and uncertain ; sometimes paretic phenomena appear, especially in the posterior portions of the body. If still standing, the head becomes much depressed, but, as a rule, the diseased animals are found lying down in a dark and se- cluded corner, with the nose buried in the bedding. An extremely fetid diarrhoea frequently marks the approach of a slow, fatal termi- nation of the disease ; the voice becomes very peculiar, faint, and hoarse, the sick animal manifests the greatest indifference to its surroundings ; emaciation and general debihty increase very fast ; the skin is hard, dry, and dirty, the more so according to the dura- tion of the disease ; death ensues under convulsions, or very quickly ; in some cases a cold, clammy perspiration breaks out over the body. "Wherever pigs or hogs have been ringed, the wounds thus made betray a great inclination to ulceration. In those few cases which do not terminate fatally, the symptoms gradually disappear ; the cough becomes more frequent but less laborious, the discharge from the nose becomes for a day or two more copious, but soon diminishes, and the offensive odor of the excrements disappears ; existing sores or ulcers have a tendency to heal ; the animal becomes more live- HOG-CnOLERA. 47 ly, and gains slowly in flesh and strength ; a short, hacking cough frequently continues for a long time. Patholocjical Phenomena. The morbid processes, though essentially the same, can have their seat in many ditferent organs or parts of the body. The necro- scopical aspects of the disease are consequently not always the same. AVe almost always tind a more or less extensive infiltration of portions of the lungs, as well as serous hiumorrhagic conditions in the i)ulmonary tissues. In some cases the infiltrated conditions of the lungs are so extensive that they sink when thrown into water. The degree of consolidation is largely dependent upon the duration of the disease. In some lungs these centei-s of consolidation were circumscribed and rare, while in others they were diffuse, and com- plicated a large portion of the lung. "Where the consolidation was limited, it was principally seated in the anterior lobes. In animals where the disease had progressed slowly, the different stages, or bet- ter conditions of consolidation were observable, conforming to the red, brown, or gray hepatization of pathologists — conditions of color dej>endent on the amount of blood present in the intiltnited pul- monary tissues. The greater the endothelial proliferation, and accu- mulation of inflammatory products, the greater the pressure exerted upon the capillary loops dipping into the alveoli ; hence the variation in Color, red, brown, or gray. The lymphatic and mesenteric glands were invariably found to be enlarged. In some cases they presented a brownish or blackish color, and contained not only disintegrated elements but extravasa- tions which lay between and separated the normal elements of the glands. The trachea and bronchi were filled with more or less frothy mncus, which contained desquamated epitlielium and bacteria. The mucous membrane was more or less tumefied and congested. Morbid changes were almost invariably present in the pleurte, mediastinum, and pericardium, as well as slight effusions in the ca^^ties of the chest and abdomen. Pleural ae complicate*! in the majority of cases. In some animals it was flabby and dilated, and generally congested. In the majority of cases pathological changes, which may be s;iid to be pathognomonic, were found in the ciccum 48 THE DISEASES OF DOMESTIC ANIMALS. and colon. These consisted of peculiar growths or ulcerous tumors in the mucosa. (Whether these were limited to the Peyer's patches or not the report does not say.) They varied in size and shape, and were more or less prominent above the general surface of the mu- cosa. The base of the older ones was frequently more or less pig- mented. Their size varied from that of a pin's head to a quarter of a dollar. The smaller ones were generally of a yellowish color, and projected but slightly ; the larger ones were of a grayish-brown color, or even blackish, and had usually a slight concavity in the center. The greater part of these growths consisted of connective tissue. In some cases these growi;hs, especially the smaller ones, or those of recent origin, were situated upon the surface of the mu- cosa, and were easily scraped off, leaving behind an uneven, excori- ated surface, having the appearance of granulation tissue. The older and larger tumors penetrated more deeply into the substance of the mucosa — in some cases so deeply that their removal caused perforation of the walls of the intestine. Similar productions were also found in. other parts of the intestine. The contents of the gall-bladder were found, in many cases, to consist of a semi-solid, granular, dirty-brownish substance. In most of them the ductus choledochus appeared to be thickened, so that the semi-solid condition of the bile might be attributed to absorption of its fluid elements, due to retention. Morbid changes in the skin were frequently met with, consisting of ulcers, purple spots or patches, or diffuse redness. The blood presented both qualitative and quantitative changes. It was dirt-colored in all cases wdiere death had been caused by cxt tensive pulmonary complications, but was thin and light-colored where pathological changes predominated in other parts of the or- ganism. It invariably coagulated on exposure to the atmosj)here. The kidneys exhibited no very marked change. Microscopic Observations. (Law.) Skin. — Microscopic sections through the affected portions of the skin showed the various grades of congestion, with blocking of the capillaries, and an excess of lymphoid and large granular cells and pigment granules with extravasations and necrotic centers. With the earlier congestion there is more or less anasarca and consequent separation of the elements of the cutis, while in the later or more severe conditions a fibrinous exudation takes place, and this may even exude upon the free surface and form dark scabs. In no in- stance was formation of pus in the skin to be seen. One feature. nOG-CHOLERA. 49 which does not seem to liave been hitherto observed, was tlie impH- eation of the bristk^-folHcles. Intestines. — St^ctions through those portions of the intestines which are merely congested and reddened, but without ulceration, show stagnation and blocking of the capillaries of the mucosa and sub-mucosa, with thickening and softening of the tissues, especially of the epithelium. This last contains a great excess of granules, and aggregations of the same into cell-forms, while the ei)ithelial cells are reduced in size and contain enlarged nuL-lei. As has been pointed out by Klein, the degeneration is often the greatest around the openings of the crypts of Liel)erkuhn, and in their interior, while their cavities are frequently filled with extravasated blood. Aside from the above one frequently finds lymphoid and migrated blood-cells, hajmatine crystals, and micrococci. The ulcere, with a central slough, present at their base the same characteristics as the congested mucous membrane. The slouch is mainly composed of small nucleated cells and granules, and mi- crococci. Lymphatic Glands. — The obstruction of the capillaries and ex- tnivasation of blood arc most common in the cortical portion of the gland ; when the medullary portion is complicated, the extravasated blood is oftenest met with in the lymph-channels and inter-stromatous spaces, while the parenchyma seems to escape. The cellular changes are most marked in the protracted cases of the disease. Or(jans of Respiration. — The characteristic lesion of the lungs is lobular pneumonia ; the exudation being most abundant in the interlobular connective tissues, and is often of a dark color on ac- count of the presence of red blood-cells. A microscopic section transverse to the bronchioli and alveoli reveals the presence of an exudation containing a large number of round lymphoid cells, gran- ules, and in the alveoli similar accunndations. Kidneys. — Clouded swelhng of the cortical, with consequent hypenrmia of the medullary, substance. Blood. — In most cases no changes were to be observed except the presence of numerous bacteria. No such organisms were to be found in the blood of a healthy pig. DiAc^N'osis. — From the foregoing detailed description of the phenomena of tins disease, it is evident that there is but little difficulty in its correct recognition, especially when appearing in a number of swine at the same time. Proonosis. — This is always unfavorable, for even though indi- viduals may survive the attack, still the ravages of the disease are 4 50 THE DISEASES OF DOMESTIC ANIMALS. sucli as to almost destroy their value as marketable animals from an economical point of view. Treatment. — On account of its difficulties, medicinal treatment of swine is in general almost useless, and with this disease truly so ; the antizymotics are, however, indicated in unison with tonics. Prevention. As in all infectious diseases, of whatever nature, the aim of modern medicine is prevention. On account of the great liability to extension peculiar to this porcine pest, the regulations of prevent- ive medicine must be fully as much of a general as of a local character. We shall follow Mr. Law in considering this question. He says : " One farmer may easily eradicate it from his swine, but, so long as it continues to prevail among those of his neighbors, his stock is daily subjected to the danger of renewed infection." This being the fact with reference to the individual farmer, it is equally the case in every township, county, or State. In our East- ern States the pest is almost invariably due to the importation of diseased stock, and, though from the lack of pigs it never gains wide extension, it illustrates the infectious nature of the disease in the West. To secure a complete or even restricted immunity from its ravages, active measures must be taken over the entire land, and this can only be done under the supervision of one central, con- trolling power, with the necessary number of local authorities. The following measures should be adopted : 1. The appointment of local inspectors to carry out the measures necessary to suppress the disease. 2. The injunction on all having the care of or ownership of hogs, and upon all who may be called upon to advise concerning the same, or to treat them, to make known to such local authorities all recog- nized or suspected cases of the disease, under a penalty for any and every neglect of such duty. 3. The obliging of the local authorities, under the advice of a competent veterinary inspector, to see to the absolute destruction of all pigs suffering from the pest, and all that have been in contact with them, and their burial in some isolated place, and the thorough disinfection of the pens, utensils, and persons around them. (It will frequently be found most advantageous to the interests of all concerned, to kill and bury the hogs in their pens, and to burn the latter, when of wood, as well as the utensils, and to erect new pens at some place properly distant for any new lot of hogs.) HOG-CnOLERA. 51 4. The complete isolation of all domestic animals wliicli have been in contact with the diseased pigs, and in all cases of sheep and rabbits, the destruction of the sick when this shall be deemed neces- sary. 5. "When all the pigs in an infected herd have not been de- stroyed, the remainder should be placed upon an official register, and subjected to daily inspection by the veterinaiy inspector, so that the sick may be removed and killed on the first indication of disease. G. Sheep and rabbits which have been in contact with diseased hogs should be treated likewise, and none should be removed from the fiock until after the lapse of a month from the last appearance of disease among them. 7. All animals and birds, wild or tame, and all persons except those employed in the work, must be carefully excluded from the infected premises, and until the same have been pronounced safe, after careful disinfection, etc. S. The losses sustained by owners from the compulsory slaughter of their hogs should be made good by a valuation to be fixed by a competant board of assessors. 9. Such reimbursement should be forfeited by owners who fail to comply with the law in properly notifying the authorities of the real existence or suspicion of the presence of the pest among their swine. 10. A register should be kept, in prescribed form, of all hogs kept on farms within a certain radius of infected herds — say one mile — and no removal of such animals should be permitted until the disease had been pronounced at an end, unless by special license from the competent authorities, after the veterinary inspector had pronounced the herd in question to be absolutely free from every suspicion of the disease. 11. Tlailroad and shipping agents of adjoining stations to in- fected districts should be forbidden to ship pigs, excepting by license of the local authorities, until the plague luis been pronounced at an end in such districts. 12. "When infected pigs have been conveyed by rail, boat, or other means of transport, measures should be taken to insure the thorough disinfection of such vehicles of transport, as well as the bams, docks, or yards, or other places into which the diseased ani- mals may have been turned. 52 THE DISEASES OF DOMESTIC ANIMALS. DISEASES OF CATTLE. Cattle assume bj far the first place among our domestic ani- mals, from an economical point of view. The prosperity of a nation might well be estimated by its wealth in cattle. Of all animals, they supply the greatest proportion of our animal food. "Without beef and milk, we could hardly think ourselves capable of existing. Assuming this rank, then, as a source of food, it is self -apparent that the greatest care should be taken in keeping such animals in a hygienic — i. e., healthy — condition. Animal hygiene differs much from human : 1. The animals must be kept healthy. 2. They must be kept healthy, so that they may yield the great- est possible return to the owner, be it work, flesh, milk, or other products. To attain this end requires the greatest attention on the part of the owners. To attain it economically,, the owner must pay attention to the different characteristics of each animal, that no food goes to waste. One animal fattens easier than another on the same amount of food. One cow yields more milk, or one ox performs a like amount of work upon food that its neighbor will not thrive upon. But in many instances, and it is with these we have especially to do, animal hygiene imposes upon the owner a responsibility that has, up to the present time, almost escaped appreciation. It is the imperative duty of owners^ or breeders of animals, to study every influence that may possibly have an injurious effect upon them, when destined to be articles of human consumption, either as flesh or milk. Thus we see that the interests of public health demand the greatest and most studious care of the water, feeding, and surround- ings of such animals. We are not going too far when we assert that this branch of animal hygiene has been almost entirely neglected, not only by the owner, but by scientists as well. Tape-worms are not by any means an uncommon occurrence in man, yet how few people realize that one variety is derived from the consumption of improperly cooked beef ! An instance comes to our mind of an M. D., who enjoyed a large practice, that came to us with the segments of a tape-worm, but could not believe it was, because the patient never ate any pork. DISEASES OF CATTLE. 53 On being told that man also obtains such a parasite from eating beef, he was eomi)letelj surprised. The name whicli science has given to this parasite is Tamia medlo-canellata, or, better, saginata. This parasite exceeds in length that which we have j)reviously described as being obtained from i)ork. Its sections, or proglottids, are also broader and thicker. Tania solium, or armaUi^ derived from pork, has its scolex, or head, armed with huuks, wliich is not the case with the one we are at present considering. This fact at firet led naturalists to think they had before them one and the same tape-worm, the dilferenccs in appearance and formation of the heads representing different stages of development, the armed parasite representing a youthful, the unarmed an aged, period in its exist- ence. This has been clearly demonstrated to be a mistake. Pro- glottids of tffiuia saginata fed to young swine failed to produce cys- ticerei, or measles, while the same when fed to calves were followed by positive results — i. e., the development of cysticerci of the un- armed tape-worm in the intertibrillar tissue (Leuckart, Mosler, it al.). As to their presence in cattle, Dr. Thudicum * says : " The question why the cysticerci of ticnia saginata have never been observed in the flesh of cattle, with the exception of those cases in which they have been intentionally reared, is of great inter- est and importance, from a sanitary point of view. It is possible that these bladder-worms are present in the musculature of cattle in very small numbers only, and consequently do not present any such striking appearance on section of the muscles as is produced by measles in the muscles of swine. For while a pig would devour an entire tape-worm if it came in its way, a calf would refuse to eat it, if it could avoid doing so ; hence, only free eggs or single proglot- tids, adhering to or concealed in the herbs making up the ordinary food of cattle, could be introduced into their systems. Thus, cattle driven along a road or path would ])c liable to snatch a mouthful of grass, and with it a proglottid of the bookless or five-cu})pod ta])e- worm. The very circumstance of tJie scarcity of cysticerci in the flesh of cattle facilitates their importation into thi' human intestines. The single specimens are not discovered, and consequently not avoided ; hence, the taenia derived from them live in almost all countries of our globe, and infest the black and white man, the Mongol, the !Malay, and the Indian. I have examined many thou- sands of specimens of beef from many hundreds of bodies of beeves, and have never yet found a cysticercus of this ta?nia in the flesh or * Report to the Privy Council of Great Britain. Sec seventh report, London, 1865. 54 THE DISEASES OF DOMESTIC ANIMALS. any other organ. Probably if calves and heifers were systematically dissected with the same care as human bodies, these cysticerci would appear as frequently as the trichinae or the cysticercus cellulosse in man, both which parasites were discovered in the anatomical thea- tre, and without anatomical dissection would no doubt have eluded the vigilance of science much longer." As said previously, taenia saginata is found in man in all parts of the world. It seems far to exceed taenia solium in its prevalence among the inhabitants of Austria proper and Lower Germany, while in North Germany taenia solium is more frequently met with. It has been met with in England, and a case of invasion is also report- ed in an Indian in our own country ; but well-ordered statistics in this regard are so out of the general course of events in these two countries, that we are not justified in assuming that the populations of the same are so much favored above their fellow-men in other countries. With reference to protection from this parasite — 1. We must have a well-organized system of inspection of all animals slaughtered, by competently educated men. 2. The people must be educated in a knowledge of these dan- gers, and also in the means necessary to their prevention. a. Without the active co-operation of the jpeojple^ we can hope for little successful reform in this country. 3. The consumption of undercooked meat must be looked upon as dangerous to health. Cattle are also subject to several diseases which threaten the public health, from the fact that they are transmissible to man by means of infectious elements peculiar to each of them. " Foot-and-mouth disease " is the common name given to a pe- culiar vesicular eruption which afflicts cattle on the parts indicated by the above name, as well as upon the ud'der of milch-cows. This disease has also been observed in sheep, swine, goats, the deer family, occasionally in the horse, and cases have been reported among dogs and turkeys. Further, numerous cases of infection have been reported among human beings. Fleming says : " It has caused almost as much loss and trouble to the farmers of Britain as has the contagious bovine lung-plague. In 1876-'77 this disease was reported as infecting 11,064 cattle, 4,809 sheep, and 1,904 swine in the kingdom of Prussia. It is needless to say that no statistics exist as to its extension among cat- tle and other animals in the United States." The asssertion that animals affected with it have been exported DISEASES OF CATTLE. 55 from this country and landed in England, makes it probable that the disease has attained a foothold among our animals. But ^vhere i Veterinary science is in a state so much less than embryonal in this country, that no one knows whence these animals came ; whether they were diseased when leaving here, or what portion of them was diseased. This disease is transmissible to man. So far as my knowledge extends, this has only taken place from diseased cows. Yalentine, of Italy, 16l>5, noticed the synchronous appearance of a i^ustulous eniption in the mouths of human beings, and a similar disease among cattle. Sagad, 170-1, was the first to notice that hu- man beings acquired the eruption from the consumption of milk from cows affected with the same. Ilertwig (of the Veterinary Institute, Berlin, Prussia) first proved the same by direct experi- ment, lie drank daily for four consecutive days a quart of milk taken from cows having the disease. On the second day he ob- served a mild fever, pains in the limbs, headache, a dry and hot throat, and a peculiar sensation in the hands and fingers. These mild phenomena continued about five days ; then the lining of the mouth became swollen, especially the covering of the tongue. In a short time small vesicles began to develop. At the same time that these eruptions appeared in the mouth and on the lips, ap- peared an eniption of similar character upon the hands and fingers. Two medical practitioners also subjected themselves to the same experiment, and at the same time similar results followed. All three recovered completely. (Bollinger, in Ziemsscn's " Ilandbuch der Pathologic," vol. iii, p. G37.) The danger from the consumption of the milk of cows afflicted with this eruption is most emphatically demonstrated by the fact that young animals fed upon the same frequently perish in conse- quence of gastro-entcritis, i. e., inflammation of stomach and bowels. For man, milk from such cows, to which ninety per cent normal milk has been added, is still dangerous when consumed. Cooking the milk from such cows completely destroys its infectious qualities. Bollinger gives the following examples of the eniption of the disease in human beinf]:s bv indirect infection : "A boy had a severe aphthous eruption in the mouth after biting the edge of a pail which was polluted with the droolings from the mouth of a diseased cow." " A man accidentally infected himself by putting between his teeth a knife which had been pol- luted in the same manner." "Another infected himself by chew- ing a piece of wood which had been used to clean the mouth of a 56 THE DISEASES OF DOMESTIC ANIMALS. diseased cow." " A veterinarian had a long-continued and painful eruption in the mouth from touching the internal part of the same with his finger after having handled a diseased cow." In the " Preussische Mittheil. aus. d. thierarztlichen Praxis," 18Y4:-'T5, are given three cases of aphthous eruption in the mouths of men who had drunk buttermilk which had been taken from a cow having foot-and-mouth disease. On account of the paucity of observations from competent medi- cal men, little is known about the disposition of mankind to this dis- ease. Doubtless, as in other infectious and contagious diseases, some persons have a far greater disposition to infection than others. Bol- linger says, " Notwithstanding the ruling opinion to the contrary, the disease is much more frequent among human beings than expected." Numerous observations have been made of the synchronous en- zootic eruptions of this disease among cattle and an eruption in the mouth of human beings. The outbreak of this disease among human beings is only to be prevented by competently educated and trustworthy veterinary in- spectors for all dairies, and by the exact isolation of all diseased animals. Such milk might be cooked before being offered for sale ; but the danger of insufficient or neglected cooking is too great to justify such a procedure, so that its sale should be strictly forbidden, and, if persevered in, as strictly punished. Such milk, after heing thoroughly coolced, could be appropriately used for feeding swine. Whether the consumption of butter and cheese made from such milk is dangerous to mankind is an open question requiring more extended and critical observation. Another subject which has not, as yet, received by any means the attention which it deserves is, the changes produced in milk chemically, and especially microscopically, by the presence of in- flammatory conditions of the udder of the cow. a. The influences of such milk should be critically tested by means of feeding experiments upon young and healthy animals of the same and different species ; controlled by feeding young ani- mals from the same mother, or of as nearly as possible like age and constitution, upon the same material. h. Are there in such milk, from diseased udders or single cisterns of the same, such microscopic changes as to allow their recognition when mixed with milk from perfectly healthy cows ? Fiirstenberg * has gone into this subject with no inconsiderable * "Die Milchdriisen der Kuh," Leipzig, 1868. DISEASES OF CATTLE. 57 deirree of exactness. From his and other researches it is evident that changes in the constitntion of the milk are produced by so sHght a change from normality as a hypentmic (increase of the qnantity of blood) condition of the interstitial and subcutaneous tis- sues of the udder. A comparison of such milk with normal, or, when but one cistern is complicated, with milk from the other cis- terns of the same udder, has shown that the solid elements are greatly augmented at the expense of the fluid ; especially are the casein and albumen augmented, while the normal milk contains more milk- sugar, and the so-called "extractives" in greater quantity. The inorganic elements are also considerably increased in the milk from diseased udders. In other words, such milk assumes characters simulating those of colostrum, containing the well-known colostrum bodies, having a yellowish-white color, is viscid, and coagulates easily. In such a secretion, Fiirstenberg found the results of chemical analysis to be as follows : Water 81 • VS9 Solids 18-211 Total lOUOOO The solid elements were : Fat 5-210 Casein and albumen 8 • 887 Milk-sugar and extractives 3 • 070 Salts. 1-044 Total 18 211 These 1-044 salts consisted of : Phosphoric salts and oxide of iron 0 • 384 Carbonates of lime O'lOS Chloride of sodium (cooking-salt) 0 003 Soda 0 549 Traces of sulphuric acid 0 - 000 Total 1 044 From the non-diseased parts of the same udder the results of the analysis were as follows : Water 88-583 Solids 11-417 Total 100000 58 THE DISEASES OF DOMESTIC ANIMALS. The 11-417 solids were : Fat 3 Casein 3 Milk-sugar and extractives 4 Salts Total 11 The mineral elements were : 405 218 092 702 41 T Phosphoric earths and oxide of iron 0-317 Carbonates of lime 0*146 Chloride of sodium 0*004 Soda 0-325 Traces of sulphuric acid 0-000 Total 0-702 The same is true, except in degree, of the more excessive grades of inflammation. The important question is, Is such milk harm- ful, and to what extent f May not the only too frequent cases of so-called " summer-com- plaint " of children, especially of those brought up on the bottle, be traceable, in a measure, to feeding them upon milk containing these colostrum-like elements ? We know that colostrum exerts a gentle purgative influence. Is it, then, going too far to (in an a priori manner) assume that such milk, when continually given, may produce more serious and lasting effects ? This can only be proved by direct experiment upon young ani- mals, which can not be done except at some expense to the State. It is, indeed, done by children, at no expense to the State, but at a fearful cost of human life, and all that is needed to close the evi- dence of this human vivisection is the competent veterinary expert at the milk-fountain end of the route, and the exact medical observer at the other. I think there would be little difficulty in establishing the connection between cause and effect, if animal life is not too precious and too tender for sentimental persons who esteem it above human at the present day. While every one is crying out for more economy in reference to State expenses, and while many expenses can doubtless be cut down with great benefit to the people — for in- stance, the number of representatives might be greatly lessened, with a corresponding increase in quality — might it not be well to call to mind the old adage that " it is not well to hold on to the spile with all one's might, and not look out for the bung." DISEASES OF CATTLE. 59 The work of State boards of health is not surely to be limited to gathering statistics of mortality in man, or ins])ecting our water- sources alone, but should extend to the investigation of those experi- ments by which alone the true causes of disease may be discovered. We are too ajit to satisfy ourselves with iine-sounding hypotheses with regard to the origin of many so-called strange diseases, which a few exact experiments would soon send to the winds, and which would lead to the discovery, if not of the cause or causes, certainly of means for their prevention. The real germ of small-pox contagion has never yet been posi- tively isolated, although many fond supporters of the micrococcus- germ theory cherish an idea to the contrary ; yet careful experiment and exact observation, in unison with practical experience, have taught us that exact attention to, and universal application of, vacci- nation, is an almost infallibly sure means of prevention against its deadly ravages. AVith regard to this very milk question, a few facts, gained from actual experiment, are worth thousands of surmises from 2)racticing physicians. To this end State boards of health should have at their com- mand an experiment station, under the control of a competently educated person as superintendent and observer of the experiments. Such a person should be a veterinarian, and be at the same time a member of the State Board of Health ; the advantage to such boards of such a member is by no means appreciated at the present time, either by the members of such boards or by the people at large. With reference to the expenses of such a station, the question for legislators, and also for the people, to consider, is not one of im- mediate outlay, but whether it is cheaper to spend a few thousand e States or cities done their whole (hdy when they have appointed inftpectors to examine milk after it has left the producer^ as it ?.* rfady for delivery to the consumer ? If, as I can but think, experiment will prove that the consump- tion of milk from cows having diseased udders, so called "garget," is fraught with danger to human health, then city im^pcction^ or de- livery inspection^ is next to usdesn^ and the place for the most im- portant inspection is at the stable of the jrrodncer. All such cows should be isolated by an official veterinary in- 60 THE DISEASES OF DOMESTIC ANIMALS. spector, and tlie sale of the milk from such isolated cows for human consumption should be punished by most severe penalties. In fact, the inspection of the milk as it is delivered to the dis- tributors for immediate consumption can only lead to the discovery of dilution — that is, cheating in value — 7iever to the discovery of an unhealthy or absoliUely diseased fountain-head^ i. e., cow or cows. The unquestionable guaranteeing to the public that the cows producing the milk are healthy is, in my opinion, far more a matter of necessity, from a hygienic point of view, than the discovery of a varying degree of watery dilution, always providing the water it- self is pure. In the one case, we have discovered a simple swindle ; in the other, what might prove to be the cause of serious constitu- tional disturbances among the consumers. It may not be known to many milk-producers that medicine given internally, and many things, such as salves and dressings, especially those used against insects, applied outwardly, are capable of exert- ing an influence upon milk which is very likely to be disturbing, or even injurious, in a far more serious degree to the consumers. The following examples, casually gathered iu my reading, will suflBciently testify to this remark : Guenther * found antimony in milk after feeding the tartrate to a cow. Harms observed a hsemorrhagic diarrhoea in two dogs and three young goats, after feeding them with the milk from a cow which had been given a large dose of the above-mentioned tartrate — forty-six grammes — the day before, Klink f demonstrated the presence of quicksilver in the milk of a woman afflicted with syphilis, that had been subjected to the blue- ointment treatment. According to Henry and Chevallier, cooking-salt, bicarbonate of soda, sulphate of soda, and iodide of potassium, may be discovered in milk when given to animals. Twelve cows were so infected by carbolic acid, which had been used in a strong solution to disinfect the stable, that human beings who used the milk, both cooked and uncooked, became sick, but finally recovered. \ A large number of persons in Rome were poisoned from the use of goat's milk. || The disease, as it appeared in these people, was strongly characteristic of cholera. Some persons recovered in * " Jahrcsbericht d. Thierarzneischule zu Hannover," N"o. 6, p. 72. f " Vierteljahrsschrift fiir Dermatologic u. Syphilis," 1876, p. 207. X Scholtz, "Preussische Mittheil.," 1874-'75, p. 109. il " Med. u. Chivurg. Centralblatt," 1876. DISEASES OF CATTLE. Qi the course of seventy-four liours, but the majority were ill for some four or iive days. The violence of the symptoms was in direct pro- portion to the (quantity of milk consumed. The suspected fi^oats were subjected to a careful examination by a veterinarian, but noth- ing abnormal discovered. Their food was next critically examined, and the following four poisonous plants Avere found in it: '" conium maculatum," " clematis vitalba," " colchicum autumnale," " plum- bago Europea." An examination of the milk vomited by the sick people revealed the presence of colchicum, which was looked upon as the cause of the disturbance. Tuberculosis of Cattle. This disease of cattle, but especially the milch-cow, is now play- ing a most sensational role in the discussions of hygienists, more esjjccially those of Germany. That the tendency or disposition to this disease is transmissible from parents to offspring has been placed beyond all question by the observation and experience of stock-raisers. This fact is also well enough known, but by far too little appreciated, by human be- ings with reference to their own race. Dr. Bowditch, of Boston, has clearly shown the influence which long-continued residence in low, damp, unhealthy localities has upon the generations of the older ISTew England families in extending or keeping alive this disease ; but the medical profession has been alto- gether too silent with regard to hereditar}' influences. Mueller * says that, basing his opinion upon 988 cases of per- sonal observation during the course of nine years, in 21*8 per cent of the same the parents had also suffered from tubercular consump- tion. This percentage increases to 28*0 per cent, if we take into consideration the grandparents, brothers, and sisters. Other ob- servers assume that thirty-eight per cent of the deaths from tuber- cular consumption in human l)eings is due to hereditary influence. If, as said, stock-raisers have learned a lesson from costly experience in this regard, and are applying principles of selection or exclusion in their breeding of animals, is it too late to apply like principles to human beings ? Is it not liigh time that the principles of scientific breeding should be applied l)y man to his own species ? I>eauty, form, money, position, should all play their aj)propriate part in the selec- tion of the partner for life by man or woman ; but, as the natural result of marriage, as the result of being made male and female, is * "Inaugural Disscrtatioa," Bcrnc, 1876. 62 THE DISEASES OF DOMESTIC ANIMALS. the production of eliildren, is it not still more imperatively de- manded of us to take the health of these products of our lust more frequently than our good sense into earnest consideration by select- ing a partner from families in which these tendencies have attained the least possible strength ? Have we any right to condemn children thus to lives of misery and early graves? What stock-raisers do for their pockets, man- kind should certainly have sense enough to do for their own off- spring. " 'Tis through ignorance they do it." The blame falls upon the shoulders of an incompetent, avari- cious medical profession. Consumptive families bring large fees, help to buy corner-lots, and enable the great doctor to ride com- fortably about with coupe and coachman. But to return to our subject. This disease of cattle has been practically known to exist for a long time. Its cause has been sought in all sorts of absurdities, such as acrid or irritable substances in food or water. Even hereditary influences failed for a long time of their due appreciation. In Germany the disease is also known as the " Franzosenkrankheit," or French disease. It probably received the name when everything evil which befell the German race was only too willingly attributed to their French neighbors as well as conquerors. The first intimation that some irritating or infectious elements were contained in the milk of cows having this disease is due to Gerlach, the most noted of all German veterinarians, and late di- rector of the Royal Veterinary Institute at Berlin. The experiments of Yillemin, Klebs, Orth, and many others, have amply demonstrated that the elements from tuberculous dis- eased lungs, lyrnph-glands, and other organs, contained some pe- culiar infectious material capable of producing a similar disease when inoculated upon, or in some cases fed to, animals by way of experiment. With reference to the milk of tuberculous diseased cows, the honor of priority is unquestionably Gerlach's. Here we have to do with a question of manifold character. ]N^ot only is the j)ublic health threatened, but both the nation and each individual dairyman, or cow-owner, has to face a question of no secondary economical importance. If the experimental results obtained by Gerlach and other ob- servers, both German and French, become universally accepted, then governments have no other recom-se than to order the most exact DISEASES OF CATTLE. g3 supervision of the cattle in their respective countries, by wliich the disease may be discovered, and their sale as meat at the earliest pos- sible moment of such as are suitable. All others, in which this is found unjustitiable on account of their condition, must be turned over to the knacker. The loss and expense of such a procedure can be best appreci- ated by the expert acquainted with the extreme extension which this disease has aecpiirod among cattle, especially milch-cows. If any government undertakes to stamp out this disease, it will find difficulties by far exceeding those connected with a t^iaiilar pro- cess by any other contagious malady. The adage, '' Touch a man's pocket and you touch his heart,'' will be more than sufficiently verified. In Germany, where the majority of the milch-cows are stall-fed, and that, too, in poorly ventilated, ill-arranged stables, this disease has acquired an extension of which we can at present make no ap- preciation in this country. The assertion of the infectiousness of the milk from such cows raised a perfect storm of abuse in Germany, which poured down on the asserter's head until he died. The more ignorant, lazy, and intlifferent men were, the louder they abused. jMany men who were professors at the schools joined in the cry, " Down with him ! " without ever making the attempt to prove the assertions wrong by direct experiment. Succeeding experiments have, however, es- sentially strengthened the assertions of Gerlach. As these fii*st experiments * with reference to so momentous a question are worthy of all attention, I take the liberty of noticing a very few of them in this place. Having a cow afflicted with tuberculosis that still gave milk, it was resolved to use the same to test the question " ic/tet/wr the milkfi'om such a cow is capable of producing a similar disease in yo>infj animals \rhen fed \ipon it.''^ f The cow was seven or eight years old, much emaciated, respira- tion difficult, and had a rough, weak cough ; vesicular respiration perceptible over all parts of the thorax which inclose the lungs, but numerous unnatural, especially dry " rdles '' were perceptible. In no place vcas the percussion deaden&l. No fever. Appetite good. Daily milk quantum, 1,500 grammes. After the lapse of three * It is not our purpose here to go into detail with reference to these experimcnls, but we will refer those interested to the " Veterinnrv Journal," London (England), vols, viii^ ix, and x, where they will find abundant material. f Gerlaoh, " Experiments with Reference to the Milk of Cows having Tuberculosis.' " Jahresbcricht d. Thicrarzneischule zu Hannover," 1868-'69. 64 THE DISEASES OF DOMESTIC ANIMALS. months the cow was killed. The emaciated condition had grad- ually increased, the milk-secretion likewise decreasing : in the first month the yield of milk decreased 600 grammes ; in the second, 500 grammes, and during the last eight days the secretion ceased en- tirely, although the animal received all the nourishment she could consume. '■'■Autopsy. — The inner thoracic walls, the diaphragm, and the mediastinum were covered with numerous tubercles of variable di- mensions ; the pulmonary pleura, or covering of the lungs, was far less complicated. The lungs were voluminous, and double their normal weight, l^odules and tubercles were distinctly perceptible on palpation. The bronchial lymph-glands were hypertrophied — enlarged — ^hard and nodulated. Cross-section of the pulmonary tis- sues revealed the presence of numerous tubercles and tuberculous devastations ; large and small cavities filled with a muco-punilent mass, others with caseous material; numerous miliary tubercles were disjjersed over the pulmonary tissue." With the milk from this cow were fed two calves, two pigs, one sheep, and two rabbits. The first calf died from an accidentally ac- quired disease. Calf No. 2. — A healthy, well-nourished caK, eight days old, was fed with milk from the above-mentioned cow, for a period ex- tending over one and two thirds months ; at first it received 1,000 and later 300 grammes of milk daily, an average of about 650 grammes per day ; in fifty days the whole quantity of milk con- sumed amounted to from 30 to 32 kilogrammes. Aside from this the calf received other milk ; later, diluted milk and oatmeal. Neither phenomena indicating the presence of disease, nor disturb- ance of the nutritive functions, were observable. The calf was killed one hundred days from the time that the experimental feed- ing began, and fifty days after the feeding with milk from the tu- berculous cow had ceased. Autopsy. — The pleura of the shai*p edges of the right lung was covered with delicate red, filamentous excrescences, which extend- ed as a fringe about a centimetre beyond the edge of the lung. Here and there this neoplastic production formed a connected mem- brane in which were to be seen miliary tubercles, as refracting points. The costal pleura, the inner lining of the ribs, was also irreg- ularly covered with a membrane of similar character. In the lungs were to be seen tubercles, otherwise the parenchyma was normal ; immediately under the pleura were to be seen four small and six miliary tubercles, and eight more were to be seen in the loose inter- DISEASES OF CATTLE. (55 lobular tissue. The smaller tubercles were more transparent, and bad a grayish color, having a firm organic character ; in the center of one of the larger ones was to be seen caseous material. The bronchial lymph-glands were much enlarged ; inwardly disturbed by many purulent and caseous centers ; here and there lime-salts 'were perce])tible ; tlie tuberculous centers extended prominently above the cut surface of the gland. The mesenteric and other glands presented a similar character. The microscopical examinations of the tubercles gave the same characteristics as those of man. Some of the experiments Avith the other animals mentioned previously gave negative, wliile othere were followed by positive, re- sults. These and other more recent experiments prove that the milk from cows complicated lo'ith tuberculosis is not only ]iarmful, hut that it also contains elements of a specifically dangerous cTiaracter / it is capahle of generating elements of a similar character : it there- fore hears the character termed infectious. Wliile I will not go so far as to consider the above-noticed and other experiments as conclusive and unquestionable evidence that the milk from tuberculous cows (and why not human mothers ?) will at all times produce tuberculosis in young animals fed on the same, yet, such is my confidence in the value of the experiments made by Gerlach and still later by others, that for myself I have no doubt whatever that the milh from tuberculous coios and mothers will, in the greater numher of cases, generate tubercles in young ani- mals when fed with sufficient quantities, and for a sufficient length of time, to produce infection. The casual reader might perhaps fail to see the point to which these conclusions necessarily lead us, viz., that if young animaU can be thiis infected, what is there to prevent the same taking place in babes brought up on the bottU ? I do not wish to place myself before the public as a visionary alarmist. Here are facts, however, induced from carefully executed ex- periments, and by a man noted for his exactness and trustworthiness in other branches of researches. Bollinger has summed up the feeding experiments upon young animals, with the milk in question, as follows: '• Three pigs — one successfully, two doubtful. " Three calves — two successfully, one prematurely died. " One lamb — one successfully. " Two dogs — two negative results. zr AvrT4-.is :. STT sg^sSirv^ TBggTrtr? ; "QSS ^}t^ST ms rsssarss. t&eT4» -1 m ■ :.h u^ ; Tarn ^i. aire ■fjH iiri:. _ ".id to ie • , 0 to tliS Aprf ^ . ' "-■t HL m- ■^ 1 12. tr. ■», 1 '^ tr&ci i DISEASES OF CATTLE. (J 7 cavities in the same, and she raised purulent ichorous sputa. She died from the disease Julj 23, IS 76. ** 6. Nurse Sanger had the habit of removing the mucus from the babes' mouths bv means of suction with her own ; and of blow- ing her own breath into the mouths of asphyctic children ; and, in general, treated children in a manner which rendered it possible for the expired air from her own lungs to get into theirs, kissing them much, etc. ** 7. In three of the cases of tubercular meuingitis which came to my personal observation, the sickness began with bronchitis- '* S. Meningitis tuberculosa is not an endemic disease among children at Neuenburg. In the nine years, from lS0G-'74, only two deaths are reported from this disease among children under one year old. Of twelve children, under one year old, that died in 1S77, only one died from this disease ; the parents of this child were both subjects of tubercular consumption.^' These cases, and those which follow, that were made by an ac- complished veterinarian, in connection with the experimental testi- mony which we have brought together in a simply suggestive but by no means exhaustive form, should be more than sufficient to call the attention of every reflecting man and woman to the fact that tuberculosis is not only a disease, the disposition to which is transmissible from parent to offspring, both human and animal, but that it is, under certain circumstances, a highly contagious and in- fectious disease. They tell tis in warning words that we mtist not only be most careful in selecting our partner for life, but in the selection of the nurse, or maid, for children, and, when neoeeeary, Oic coic from which we are to give them milk, Th^ inifuertCf of th< expired air from the lung9 cf caHU afiieUd vcith the disease called tuberculofis upon other animals of the tame sjKci<^ confined in the same ttahU tcith them. This question is one of vast praedcal and economical impor- tance to the farmer and dairvman. I much reg^t that I am so entirely limited to the observations of foreigners upon cattle in their own countries rather than to observations gathered in our own country ; but this fact should stimulate us to more careful consideration of these questions, even though it be late in the day that we begin. A German veterinarian. Albert, contributes a very thoughtftd and interesting paper, detailing personal observations bearing upon this very point, in the " Wochenschrift fur Thierheilkunde,'^ yoe. 30 and 31, ISSO, under the title '* The Tuberculosis of Cattle as an 68 THE DISEASES OF DOMESTIC ANIMALS. Infectious Disease." The following is a free translation of the es- sential points of this paper : Although heredity is unquestionably a very important cause in the generation of this disease among cattle, still it does not suffice to explain the great extension which the same acquires among them ; especially is it insufficient in answering for the eruption of the disease among cattle in stables where no breeding takes place, or where the young animals are brought in from other places. In such stables other causes must be brought into action, and these are the transmission of the disease from one animal to another. I have observed that when there is in a stable one individual which contains in its organism the conditions necessary to the extension of the dis- ease— tubercular process in the lungs — the disease extends to the other animals — cattle — in the same stable which have been there for a sufficient period. This seems to conform to the fact that tuberculosis is a disease peculiar to our domesticated cattle, but not to the wild ones of the plains, and agrees with the experience that certain stables are looked upon as peculiarly favorable to the gener- ation of the disease. Of the peculiar metamorphoses which tubercles undergo, those of caseous degeneration offer the most favorable conditions for in- fecting the expired air of a diseased animal. The following cases will answer to illustrate the point in ques- tion: Case I. — At the time (1848) that the views of veterinary au- thors were most crude with regard to the nature of bovine tuber- culosis, I had occasion to treat the disease upon a farm where it had prevailed for a long time, and caused much loss to the owner. Upon the farm were always kept fourteen milch-cows and cattle, a bull, and four calves. Of these, four head were sold each year, and replaced by the same number of calves. The animals sold were not always of the same age each year ; in one year the two and three year olds would be sold, in another older cows, and the third some of each, according to the fullness of the owner's purse, so that there were cattle on the farm two, six, and twelve years old. Of these older animals, I found on my first examination two afflicted with a rough, dry cough, and with accelerated respiration. As I was aware of the constancy with which the disease had pre- vailed among the owner's cattle, it was my advice to get rid of these two as early as possible. This advice was followed. The cattle were fattened, and upon being slaughtered my diagnosis was con- firmed. DISEASES OF CATTLE. 69 In the mean time every attention was given to the feeding and general care of the cattle upon the place. In 1851 I again found two of the cattle that coughed, and grad- ually hecame somewhat emaciated. The attempt to fatten them was partially successful in one, but failed in the other. Both were killed, and tuberculosis found in them. Four calves were placed in the spring of 1S52 with the cattle in the old stable, and four others placed where they were taken from. All seemed to be healthy to the spring of 185-1, when one of the calves, which had become three years old and had been placed in the old stable, began to cough. The cough was at fii*st very slight, but commenced to increase after the heifer had calved. In the following summer it again dimin- ished, to augment very considerably in the fall. This animal was put out to graze in the spring of 1855, and to my surprise became quite fat ; but upon being slaughtered the animal was found to be highly tuberculous. Of the old cattle there still remained a single cow, which we will call " A," that had always stood next to the above-mentioned animal. All the others had been sold and killed, their places hav- ing been filled by new ones. This cow had coughed for a long time ; but, not suffering in condition, she had been kept, as she was a great favorite with the farmer's wife, especially as I had not then the slightest suspicion of infection by means of the atmosphere. Every animal which during this period had stood beside this cow had begun to cough after a shorter or longer period, and, as the positions of the animals were sometimes changed, it happened that in course of time nearly all of them began to have the same sus- picious cough. The continued buying, rearing, and selling of cattle went on for nine years before I had opportunity to examine the cow "A," which was then sold to a butcher. The examination of the body and its contents resulted in finding it highly tuberculous. The re- sult of all my experience awakened in me the suspicion of the transmission of the disease from animal to animal, an opinion which was then considered ridiculous. I comnmnicated ni}' opinion to the owner, and addsed his selling off all his cattle and replacing them with new and healthy ones from parents and places where the dis- ease was not known to exist. My advice was appreciated by the owner calling in a quack to take my place. Case II. — On another farm were kept from twenty-four to twenty-six liead of cattle. In 1864 the owner bought a calf to bring up, the mother of which died a few years later from tuberculosis. 70 THE DISEASES OF DOMESTIC ANIMALS. This calf developed very poorly for the first two years of its life ; its neck and head were small and long, and its bones very small, so that the whole habitus of the animal was cachectic. This animal was killed in the fall of 1869. In the course of the winter of 1869-70 many of the cattle began to cough, and among them two, " A " and " B," so severely that my services were requested. I found all the animals in an apparently healthy condition ; only the two, A and B, were noticed to cough. By auscultation, I found in A a peculiarly marked bronchial respiration in portions of the left lung. At this time I knew nothing of the breeding, or the phenomena seen in the above-mentioned calf, which had been slaughtered. During this winter and the succeeding summer the two cattle, A and B, besides others, continued to cough. All the animals on the farm coughed during the winter of 18Y0-'71, except the yearlings and some calves which were kept in another stable. In the spring of 1871 the two cows, A and B, began to emaciate so much that it was considered advisable to kill them. The autopsy revealed the general characteristics of tubercular pneumonia, and tuberculosis of other organs. Basing my opinions upon the pre- viously mentioned experience, I made no hesitation in pronouncing all the cattle in this stable that coughed as afflicted with tuberculo- sis, and advised the owner to gradually get rid of them all. On ac- count of economical reasons, this was easier said than done, and the owner has never since been free from this disease among his cattle. During the period from 1864-'71, tuberculosis has been always present among the cattle of this owner, who has lost nineteen head from the disease in that time. The author gives four other illustrations of similar extension of tuberculosis among cattle upon other farms, and closes his remarks with the following interesting case : The milk from one of these cows had been used for some time in a cooked condition, but the condition of the cow finally became so bad it was decided to give the milk to the hogs, but uncoolied. From May of the same year, the farmer's wife noticed that the young pigs (four or five months old) fed upon this milk did not ap- pear to thrive well, and as, in the course of a few weeks three died, I was requested to make an examination of the last one. I found the same much emaciated. I found a tuberculous peritonitis with effusion in the caWty of that organ. The lungs and bronchial glands were normal; the mesenteric glands enlarged — on section of the same, found them filled with a tuberculous mass ; tubercles in the liver. In the course of a few weeks the two remaining pigs of the DISEASES OF CATTLE. 71 litter also died. I found tuberculosis in one of them, and the owner told me that the other, and another of an older litter which was with them, and fed on the same milk, were also found tuberculous on being exaiiiined. Unfortunately, in tliis country, there are not at present any sta- tistics witli reference to the extension which this disease ha,s attained among our cattle, and the same is almost true with reference to other lands. The following meager statistics may not, however, be with- out interest to the reader : Statistics wrrii reference to Tuberculosis among Bavarian Cattle for the Year 1877. Tuberculotts. Males 809. Females 4,107. 1-G2 to the 1,000. 64 under one year, or 1"31 per cent. 528 from one to three years, or 1081 " 1,846 from three to six years, or 37-80 " 2,445 over six years, or 5007 " Goring, " Zeitschrift fur Thierheilkunde," 4, 286. From January 1 to December 31, 1874, were killed at Augsburg, Bavaria, 11,331 cattle (calves excluded) ; of tliese 134 were tnhercu- lous, 1"18 per cent ; 42 males (13 bulls and 29 steers); 92 females. Of the whole number slaughtered, about one third were males and two thirds females. For the year 1876 were killed 13,241 cattle and 25,909 calves. Of these, 250 were foimd tuberculous ; viz., 243 cattle over one year old, one calf three weeks old. The percentage for 1876 was 1*84; for 1875, 1*40; for 1874, MS ; for 1873, 1-02; for 1872, 1-27. For 1876, 75 males and 168 females. Of the males, 39 were castrated and 36 were not. Statistics of Diseases found amono Animals slaughtered at Munich in 1874. "Whole number slaughtered at the public shambles : i Oxen 231 Cattle ^ fj^^^ ^^^ ^^^^j.^ g 290 Calves , 4,201 Sheep 1,563 Swine 808 Of the frequent diseases were observed : Y2 THE DISEASES OF DOMESTIC ANIMALS. Pulmonary tuberculosis in one goat and 235 cattle. Perlsucht, or tuberculosis of the serosaa 197 " Tuberculosis of the liver 29 " Tuberculosis of the udder 1 " Tuberculosis of the bones 2 " Abscess in the lungs 45 " Pleuro-pneumonia 20 " Echinococcus of the lungs 44 " Echinococcus of the liver 10 " Induration of the liver 264 " Distoma hepaticum 219 " Icterus 20 calves. Nephritis, suppurative 12 cattle. Abscess in udder and mastitis 8 " Scabies 242 sheep. Osteomalacia 9 cattle. Measles 4 swine. Slunk veal 57 calves. Nauseous appearance of flesh in one swine and 25 " "Department veterinarian Pauli reports* that 12,585 kilo- grammes of flesh were officially destroyed at the investigation sta- tions in Berlin from 18TT to 1878. Further, 1,646 cattle, 2,027 swine, 235 calves, and 714 sheep, were killed in the police slaughter- house to determine their hygienic condition. Of these, 213 cattle, 643 swine, 196 calves, and 382 sheep were found unfit for food. Of the 213 cattle, 49 suffered from general ' tuberculosis and initial emaciation,' 46 'from general tuberculosis and cachexia,' and 22 'from tuberculosis, general hydrops, and cachexia,' and 85 swine were found measly. In 998 cattle, 1,466 swine, 8 calves, and 107 sheep were found single diseased organs, which forbade using the flesh for human food." There is no subject more urgently requiring the attention of boards of health and the people than this. However important trichiniasis may be, this far exceeds it. The few experiments which have been made should be repeated by hun- dreds— yes, thousands, if necessary — by carefully selected men, and at the expense of the State, until this question is forever settled ^ro or con. "While this is being done, competent veterinarians (not empirics) should be engaged by the respective State boards of health to gather reliable statistics with reference to the extension of tubei'culosis among the cattle of each State. It would be well that the National Board of Health instigate the work. * "Mittheil. aus d. Thieriirzt. Praxis," 1877-78, p. 99. DISEASES OF CATTLE. 73 As the statistical results of the experiments which liave been made unquestionably go to prove that such milk does contain ele- ments of a spccijicalbj infectious character, there is no question that laws should he made, and executed also, so as to prevent the sale of such milk for human consumption, either for itself or mixed with other milk, in no matter how small quantities. Xo such milk should be sold ; but such cows should be strictly isolated and fattened, or condemned. This question of the specific infection of milk from tuberculous cows is no trifling matter ; on the contrary, it is one of life and death. IIow many thousand babies are yearly brought up on the bottle with cow's milk ! All the fond parents ask is, that the milk is from one cow. This guaranteed, they appear to feel perfectly satisfied. No one seems yet to have thought that a trustworthy and expert guarantee of the hygienic condition of the cow giving the milk was necessary. We make great demands, and get terribly excited about the purity of our water-supply. "We spend millions of dollars to keep the foun- tains pure, and to prevent all foreign admixtures on its passage to us. Is it not as much our duty to examine into the purity of the fountains from which comes our milk-supply ? "We can not but repeat our assertion that every State board of health should be liberally supplied with funds to be used exclusively for experimental purposes, and in every State there should be a station for such purposes. I do not know that it has ever yet been proved by direct experi- ment how much dilution it is possible to give to milk hj means of unduly watery food given to the cow, or how much the milk can be concentrated, in one and the same cow, by systematically lessen- ing the quantity of fluid given consistent with the health of the animal. The first form of feeding might he well called, dilution of milk icithin the law, while when the water is added after milking we have dilution Mnder penalty of, or vjithout, the law. Both forms of dilution are equally a swindle upon the con- sumer. An economy which does not recognize the absolute necessity of such experiments as the above is of the " penny-wise but pound- foolish variety," and never in the true interests of the public. Y4 THE DISEASES OF DOMESTIC AXIMALS. Anthkax {Carbuncle). Anthrax is the disease of all the diseases strictly due to germ-life which is best understood by scientists. Before considering it, how- ever, we desire to introduce some general remarks, and then to con- sider the subject of germ-infection, though in a very general manner. The word infectio means to pollute. The subject of infection is one of the most theoretic connected with the study of medicine. To theorize does not mean to dream of things possible, as the major part of the j^eople and too many professionals seem to think. To be called a theorist, if one is in reality such, is by no means a disgrace ; on tlie contrary, it is the highest honor that can be given. It means, truly, that one is a man capable of reasoning, both by in- duction and deduction. To be called a jfyractical man means that you know nothing but routine practice, or what one has inherited from teachers and fathers, and that we are incapable of reasoning. Theory is the connecting link, the hypothetical bridge of explanation between two known facts. These facts are, first, that something takes place; second, the phenomena by which you recognize that something has taken place. The empiric is satisfied with this knowledge. It is enough for him that a horse has colic, and that certain symptoms indicate it, and that in general a dose of a certain medicine will cure it. This is being practical. To theorize means to be able to think, and to think logically and well — to be able to trace the connection between cause and effect. If there is any disgrace in this, then those who are called theorists are generally in most honorable company. The trouble with our profession is and has been that it has never yet produced a great thinker. Xot one of the men whose names you have been taught to revere as great among veterinarians have ever been great thinkers. Even human medicine has been noto- riously wanting in this regard. Good thinkers are scarce at best. The Bacons, Goethes, Des- cartes, Humes, and Franklins of this world are always phenomenal. The great practitioners have been numerous ; the great thinkers in medicine can be counted upon the fingers of one hand. They are the men who have shaped the course of medicine for years after their death, and frequently dunng their lives. INFECTION. Y5 lias veterinary medicine ever produced a Bichat or a Yirchow ? When it docs, it will stand scientifically on a level witli human medi- cine, and not till then ; for then it will for a time give the direction to all medical research and thought. Good theorists arc ever prac- tical in the best sense of the word ; for practical does not always mean a knowledge of therapeutics alone, as many teach. An erro- neous theory, ably defended, is of more benefit to the world than a true one which lacks earnest defenders or combaters. It stirs men up, and leads to the discovery of the tnitli. Darwinism has been the greatest blessing to natural science that the nineteenth century has produced, even though all its premises should finally be proved incorrect. You have only to think of the immense increase of our knowledge of the lower forms of life, of the physiological functions of both lower and higher animals, to re- alize this. Some of our very best veterinarians are getting by far too con- ceited, and this conceit is unfortunately becoming inoculated into the rising generation. There is no such thing in existence as veterinary science. "We speak of veterinary pathologists, when in reality we have never Lad a single one. Pathologists and pathological anatomists are entirely different things, though occasionally united in one person. Bichat and Yirchow were pathologists, because they were good thinkers. Pathology is the philosophy of disease. They were or are pathological anatomists, because they could correctly read, that is, describe the results of disease. From these reaults they theo- rized ; that is, from facts they thought ; that is, they tried to tell us how the results took place, for no man has yet seen the processes of disease. AVhat we see upon the dissection-table, or under the microscope, is not the processes of disease, but the results. If we are practical in the world's sense, these results will be of no value to us ; if we are theorists, they may be very instructive, and we can become truly practical. I have said that Yirchow and Bichat were pathologists, and that veterinary medicine had never produced a pathologist. This is a fact, contradict it who nuiy. P>ut if we have not ]>:-o- duced pathologists, we have pathological anatomists, some say. Again I say, all wrong. A pathological anatomist is a man who correctly describes the results of disease, of which Rokitansky is a striking example. 76 THE DISEASES OF DOMESTIC ANIMALS. Have we produced sucli a man ? Do our text-books tell us much of the results of disease in our animals ? Some may quote to me the names of Gerlach, Roell, "Williams, Leisering, Bouley, Chauveau, Toussaint, and others, not one of whom deserves to be named with a Rokitansky, a Yirchow, or a Bichat. They have done some good experimental work, in a very limited field, and, like one solitary star shining out from a dark and clouded heaven, loom up all too conspicuously — thankful, as we are, that they have done something to make veterinary medicine worthy of notice. But where is our pathological anatomy ? "What is Roell, the best of German works on special pathology ? Has it any original pathological anatomy ? It is Rokitansky from beginning to end ; that is, human results transferred, without criticism, to animal con- ditions. Briickmliller's " Pathological Zootomy," the only work on pathological anatomy of our animals, is another abortion, born too early to have anything in it but adapted Rokitanskyism. What do we know about the microscopic pathological anatomy of the brain, the kidneys, or any single organ of our animals ? The macroscopical conditions are fairly described ; the microscopical have been scarcely thought of, but borrowed from human medicine. Have we a single contagious disease, the pathological conditions of which have been carefully studied and described by veterinari- ans ? Ko ! Do we know the pathological condition of the lungs, in direct progress from beginning to end, in pleuro-pneumonia ? Are our methods of investigation, urine analysis, microscopic technic and examination, any of them, the result of veterinary gen- ius ? No — all, all borrowed ! Then why speak of veterinary science ? These things are not written to discourage, but rather to stimulate, for I, for one, believe the day will come when veterinary medicine will have its patholo- gists who shall give the key-note to medical thought, and veterinary pathological anatomists equal to any that human medicine has had, or will ever produce. In that day we shall not grope in darkness, but shall see things as they really are. "We must learn to observe well, and, above all, to think well, and next to that to be able to express ourselves well. Medicine has its language, and the exact and logical use of language is the best characteristic of an educated man. I will illustrate my meaning by a few of the incongruities of medical literature. We frequently read of collapsed conditions of the lungs, by which is meant the dark-blue, airless spots which INFECTION'. 77 He somewliat beneath the general level of the pleura. This is real- ity atelectasis puliiionum, that is, airless. The structural changes of the lung by M'hicli this condition and true collapse are produced ai'e absolutely diliorent. In atelectasis we have a shutting olf of the supply of air, a gradual absorption of that which was present, and a consequent retraction of the pulmonary tissue, by which the blood- vessels come nearer together; a non-oxidation of the blood in the same, hence the darker color; hut tJie lung-tissite retracts, it retains its ehuticitij. In coUapsris pnlmmunn the hing-tissiie has lost its elasticity^ an entirely diiierent condition. Such a lung has lost all the springy characteristics of normal lung-tissue ; it is dead, doughy to the touch, which is never the case in atelectasis. Again, clinicians speak of hepatization, instead of solidification or infiltration of the lung. Plepatization means, indeed, solidified (liver-like), hut only to the touch. The observation and language of the dissection-table have been transferred to the bedside, where they do not belong. Each place has its appropriate language. "We speak of apoplexia cerebri, as if there were no other form of apoplexy, whereas the word means to strike down, to cease acting suddenly; hence we may also have apoplexia cordis, pulmonum, laryngia, medulla oblongata, all organs the continual action of which, or of ])arts of them, are absolutely necessary to the continu- ance of life. We here again mix up cause and effect. Apoplexy is the cessation of function, not the cause. The hremoiThages in the brain are that and nothing more ; but because in some cases apoplexy accompanies them, they are not always apoplectic centei*s. The part complicated, or the amount extravasated, causes the clinical expression apoplexy. While these things have, as it were, become sanctified by usage, they are not in accordance with the logical use of language. Concussion of the brain, by which life ceases, may be supposed to take place without ha?morrhage, yet is essentially apoplexia cere- bri, though we never hear it spoken of as such. "With reference to some of the infectious, or, better, contagious diseases, we find medical writers falling into the same error when they speak of the elements by which the disease is transmitted to human beings as "animal poisons." There are animal poisons, such as come from reptiles ; but the infectious elements of the con- tagious diseases are not, logically speaking, poisons. A poison is something which in well-defined quantities causes specific effects. Unless this quantity of a given poison is intro- duced into the system, this effect does not follow. f^^ THE DISEASES OF DOMESTIC ANIMALS. In contagious diseases the quantity necessary to infection can not be measured. The elements of infection in contagious disease multiply within the organisms into which they are introduced. Poisons do not thus multiply of themselves. The quantity of poison remains the same, unless a second intro- duction takes place. Infectious or contagious diseases have their period of incuba- tion— that is, a period elapses before the infected organism shows to us that anything has taken place. Even in inoculation the action is not immediately visible. In some diseases, as rabies, this period may extend over weeks or months, while in others only a few days elapse. By poisons the action is immediate, provided the quantity intro- duced is sufficient. Infectious diseases have their cycles, or stages. They have the above period of incubation, their period of full development, and that of reconvalescence, their " stadium accrementi and decrementi," while poisons have no such course. The diseases which are known as contagious, or infectious, do not by any means belong to a single class or group. "We have the group of acute exanthemata, such as the variolas, measles, scarlatina, certain forms of mange, the foot-and-mouth dis- ease, the maladie du coit, and the pustulous eruption upon the genitals of our domestic animals. These diseases are frequently accompanied by catarrhal conditions of the respiratory or digestive tracts, with cerebral, hepatic, or splenic disturbances ; but these latter do not constitute the essentials of the disease. They are also generally ac- companied by fever, which of itself is nothing specific, fever being a general phenomenon accompanying all serious constitutional dis- turbances. There is no such thing as specific fevers. Of specific causes there are many. "We have also a group of infectious diseases known as the acute intestinal, that tract being the chief seat of the same, though, as with the above, other parts or organs do not escape compHcatiou. Such are abdominal typhus, cholera, dysentery, and rinderpest. Then we have those of the respiratory tract, the influenzas — a collective name — pharyngitis et laryngitis diphtheritica, tussis con- vulsiva, pleuro-pneuraonia, and the malarial influenza, or pneumo- pleuro-enteritis of the horse. Also the group of septic diseases, which embraces those classed under the general names of septicae- mia or pyaemia, erysipelas, gangrena septica, phlegmonia, puerperal fever, etc. IXFECTIOX. 79 Another group embraces the so-called essential or malarial fevers, such as febris reciirrens, llava, and the Texas cattle-fever ; and, finally, the zoonoses, or contagio-infectious animal diseases, rabies, glanders, anthrax, as well as those peculiar to one species or an- other, as syphilis of man. After these general remarks we will now consider what are at present looked upon as the elements of infection, in one form or another, of all these different groups — viz. : The Bacteria. "What arc bacteria ? '*■ Cells deprived of chlorophyl, of globular, oblong, or cylindrical form, sometimes sinuous and twisted, reproducing themselves exclu- sively by transverse division, scissiparity, also by spores, bacillus subtilis, living isolated or in groups, and having affinities to the algt\»." Owing to their microscopic minuteness, it is not to be wondered at that most varying views have been held as to their real nature and place among living things. That they constitute veritiibly a contaglum vivion, that is, are living things, there is at present no doubt, various as have been the opinions as to what the true meaning of such a term should be. A living contagium is such by which the infectious elements have the principal characteristics of life ; that is, they live and die, and are capable of reproducing themselves : whether the reproduc- tion takes places within or without the animal organism is non- essential to our definition. Even very ancient writers seem to have arrived at some vague idea of the existence of a contaglum vivum. "We find the same in the writings of the Roman fathers of agricultural and veterinary literature of the fourth century, A. D, "V^aro and Columella, who asserted that many malarial fevers were caused by the penetration of lower organisms into the body. Even before the discovery of the microscope, animal organisms were supposed to have an etio- logical connection with the pest. Leeuwenhoek, the fatlier of microscopy, is said to have been the first observer who described anything like tnie bacteria. This oc- curred in 1075, while examining some water, in whicli he describes minute globules as crossing the objective field. The following year he recognized similar objects in fteces, and the tartar from the teeth, and gives such descriptions that we are warranted in assuming that they were bacteria, vibrios, and leptothrix. An author of the seventeenth century attributed the epizootics 80 THE DISEASES OF DOMESTIC ANIMALS. which prevailed at that time to the action of some sort of grass- hopper or locust, and recommended that the inhabitants make large fires to drive away or kill them, in order to prevent the diseases. Later, we find various absurd ideas being supported, and cholera, variola, syphilitic and other animals described by authors as being the specific cause of such diseases. Such absurdities led to the ridicule of the idea of living infec- tious elements, which found its counterpart in the idea of infectious gases, a theory which has been of late abandoned, owing to the great advances in microscopy and the technicalities of scientific re- search during the last ten years. The Classification of Bactekia. As early as 1773 O. F. Miiller made an attempt to classify these objects ; others followed, among them the noted German natural- ist Ehrenberg in 1838, and the Frenchmen Dujardin (18'11) and Davaine. Ehrenberg speaks of — 1. Bacteria, as filaments linear and inflexible, and gives three species. 2. Yibrios : filaments linear, flexible ; nine species. 3. Spirillum : filaments spiral, inflexible ; three species. 4. Spirochaete : filaments spiral, flexible ; one species. Dujardin (1841) classed them as — 1. Bacterium : filaments rigid, with vacillating movement. 2. Yibrio : filaments flexible, with undulatory movement. 3. Spirillum ; filaments spiral, with rotary movement. Up to this time the bacteria had been looked upon as animals, and placed at the foot of that kingdom. Later, the idea that they be- longed to the vegetable kingdom has been gradually gaining ground, and is at present almost universally accepted ; although the renowned German naturalist Haeckel places them in his intermediate class or kingdom of protista. Davaine (1859) was the first to clearly demon- strate the vegetable nature of the vibrios, and their near relation to the algte. Davaine's classification was as follows: Filaments straight or bent, but not spiral, moving spontaneously. "Wlien rigid, bacterium ; when flexible, vibrio ; when motionless, bacteridium ; when the fila- ments were spiral, spirillum. From this time on we find the study of these objects assuming a new and more exact character, thanks to the work of Pasteur, Da- vaine, Haller, Cohn, Koch, and others. INFECTION. 81 The absence of cliloropliyl distinguishes tliem from the algic, and places thera among the fungi ; a view which is supported by nearly all the best botanists of our day. The generally accepted classifica- tion is at ])res(.'nt that of Colin, and is — 1. Spherobacteria, or globular bacteria. 2. Micro or roil bacteria. 3. Desmo or tihimentous bacteria. 4. Spiro or spiral bacteria. In 1874 l>illruth, the noted surgeon and author on surgical pa- thology, published a large work upon disease-germs — viz., upon coccobacteria septica — and arrived at very different conclusions from those of Colin, wliich have not, however, gained any general accept- ance. BiUroth chiims tliat there is but one single original species of bacteria, and that all others are derived from it, viz., coccobacteria septica. This vegetable organism may present itself in two forms: the globuhir coccus, and that of rods, hacteria. These two forms may reproduce by elongation and transverse division, or may pass from one to the other. According to the variation in size, Billroth speaks of micrococcus, microbacteria ; mesococcus, mesobacteria ; megacoccus, megabacte- ria. And, according to their relations to one another, as mono- coccus, monobacteria ; diplococcus (in pairs), diplobacteria ; strepto- coccus (in chains), streptobacteria ; gliococcus, gliobacteria ; petalo- coccus (foot or base), petalobacteria. "We have said that the most generally accepted classification was that of Cohn, but, before considering it more particularly, we feel obliged to notice that of another noted German author, which is based upon the action of these germs. Xiigeli speaks — 1. Of mucorini, or mold-fungi. 2. Saccharomycetes, or budding fungi, which produce the fer- mentation of wine, beer, yeast, etc. 3. Schizomycetes, or fission-fungi, which produce putrefactive processes. This group end)races the micrococci and bacteria. I. Sphekobacteria. — Spherical bacteria are defined by their name. Tlu-y are round or oval bodies of vor}* small size. They arc sometimes found isolated, often appearing in pairs — diplococcus ; or again we meet with them in the ff)rm of chains, or articulations — streptococcus ; or united together by a sort of homogeneous material — zoogleaform. AVhcn in this condition they are young and in pro- cess of active proliferation. Sometimes they form a coating upon the surface of liquids. "When we speak of a raycoderma, they have 6 82 THE DISEASES OF DOMESTIC ANIMALS. no independent movements, but simply display the well-known mo- lecular trepidation. The function of spherical bacteria has been determined to be zymotic ; that is, ferment-producing. According to Cohn, they do not take part in the production of putrefying processes. While the above includes a distinct form of germ-life, there is no question that the spores of some other forms of germ-life, viz., bacillus, give no distinguishing means by which to separate them from spherobacteria, except the results of experimental cultivation ; as the Bible says of men, " By their fruits shall ye know them." There is but one genus of the spherobacteria, viz., " micrococcus." They are described as cells, colorless or scarcely colored, very small, globular or oval, forming by transverse division, filaments of two or several articulations in the form of a chaplet, or united in numerous cellular families, or in glutinous masses, all motionless. This genus is divided into three groups : Micrococcus chromogenes. Micrococcus zymogenes. Micrococcus pathogenes. ^ The first groups are again distinguished as to the solubility or insolubility of the coloring-matter, and are found upon vegetables, milk, etc. The second group contains but one variety of special interest to us, viz., M. urece, found in urine, where it transforms the urea into carbonate of ammonia (Pasteur). The pathogenetic micrococci are of so much more importance that we must give them particular attention. They are spherical bacteria, which are found in affections of a contagio-infectious nature, such as 3f. vaccince, being very small, appearing isolated or in pairs in recent vaccine virus, and in the pus of variola-pustules. They are looked upon as the active prin- ciple of vaccine virus. M. dijpMheriiicws. — Granular ovoid cells, isolated, or more fre- quently united in pairs, or in a chaplet of four to six cells, some- times multiplying in colonies, and extending themselves in all the complicated tissues, decomposing and destroying them. M. septicus. — Little round, motionless cells, crowded in masses or united in chaplets ; found in the secretions of wounds in cases of septicsemia, as zooglsea in callous ulcers, as isolated cells, united in pairs ^ or chaplets, in tTie serum of epidemic puerperal fever, and in all tissues, vessels, etc., in pyaemia and septicemia. Many others have been found and given specific names, espe- INFECTION. 83 cially by Ilallicr, Zurn, etc., as in Bcurlatiiia, epidemic diarrhoia, typhus, glanders, rinderpest, syphilis, gonorrhoea. II. The Skcond Group of Conx, the Micuouacteuia. — "We have here the single genus bacterium. Cells cylindrical or elliptical, free, or united in paire during their division, rarely in fours, never in chains, sometimes in zoogUea, having spontaneous movement, os- cillatory and very active, especially in media rich in alimentary material and in the presence of oxygen. As with the spherobacteria, we might divide the rod-bacteria into three groups: first, those of putrefaction, J3. termo^ llneola ^ second, those of lactic acetic fermentation ; third, the pigment-bac- teria of colored milk and pus. J3. tenno is the most common of all varieties. They are cylin- drical cells, slightly swollen in the middle, isolated, sometimes united in ])airs, two to five times as long as wide. Movements oscillatory. They can easily be produced in all infusions of animal and vege- table substances. Tliis bacterium is said to have cilia or hair-like projections from each end of the rod. It is the veritable agent and first cause of putrefaction, and hence is to be found in all cadavers where this process has com- menced. B. Ihuola is larger and found in various animal and vegetable infusions, but is not definitely known to cause a specific fermenta- tion. The other forms of lactic and acetic fermentation are not of es- pecial pathogenetic interest. III. Desmobactekia. — This group of Colin^s is of especial inter- est, as it contains the specific germ of anthrax, that germ upon which the germ-infection theor}- of disease largely depends for support. They are filiform bacteria, composed of elongated articulations, isolated, or in chains more or less extended, and resulting from trans- verse division. (In this form they correspond to leptothrix, but differ from torula in that the filaments are not constricted at the point of articulation.) They may be motionless or not, dependent upon the presence or absence of oxygen, the reaction of the medium which contains them, and other unknown conditions. Some forms never exhibit movement. AVe have here but one germ to consider — bacillus. The bacilli, are characterized as slender filament><, straight, short, or of moderate length, rigid or flexible, and as being with and with- out movement. One species is a pigment bacteria. Bacillus stihtilis. — Very slender elongated filaments formed of a 34 THE DISEASES OF DOMESTIC AKIMALS. single cell, or of two, three, or more segments. Thickness un- measurable ; well-defined flexible movement of an active or passive character. Reproduction is by fission and by globular or oval spores, which develop in the interior of the articulations. They are to be found in stagnant waters. This bacillus plays an important part in butyric fermentation. It exists in rennet, and can support a temperature of 105" C. and live in a medium deprived of pure oxj'gen, in which case it takes a peculiar form and contains persistent spores which when set free give rise to other rods. Bacillus anthracis is a species very similar to the preceding, but generally longer, and always motionless ; length four, twelve, and even fifty micrometers ; thickness scarcely measurable. Bacillus anthracis is developed in charbon — carbuncle — of cattle, man, sheep, horse, rabbit, rat, etc. ; never in dogs, the cat, birds, and cold-blooded animals. It is found, above all, in the capillary vessels. When cultivated in suitable media, such as the aqueous humor of the eye of the ox, and the different cultivation fluids, this bacillus develops spores in the interior of its segments which may germinate and develop rods. The other bacilli of this group are without any special interest. The only form of special interest is the " spirochaeton hermeieri," found in the blood of persons suffering from recurrent fever (chills and fever), but only during the access, never during the intermis- sions of the disease. Distinction of Bacteria fkom Inorganic Substances. 'No one has ever questioned the living nature of bacteria, except with reference to the most invisible varieties. These smaller forms may be often confounded with vario-us matters, such as organic par- ticles, molecular granules, fat-globules, or fatty detritus. To distin- guish them from micrococci is almost impossible, unless the greatest circumspection is taken by the observer. The detritus, or the amorphous powder, or precipitated mole- cules, of inorganic substances, though they equally well exhibit the noted Brownian movement, are to be distinguished from micrococci by such optical signs as their angular or irregular form, their lesser refraction, and their action toward certain chemical agents. The case is quite different if the molecules are of an organic nature. They enjoy, in common with micrococci, a round form, movement, and refraction. However, their form is wanting in the regularity proper to germs ; they vary in color, and their refractive INFECTION. 35 power is always less. "Warming the slides, the action of ether and other known reagents will enable one to distinguish them. The must ditKt-ult of all objects to distinguish from micrococci are fat-globules, or so-called fatty iletrUus. The difference in refrac- tion is very small, and in mucilaginous solutions the action of re- agents is not always to be depended upon. Cultivation is the only secure course to employ in cases of grave doubt. Only ,such (jlubuU's as have iJie power of multlpllcaiion are vital hodif^ : when this does not take place, we may assure ourselves that we are having to do with some form of pseudobacteria. Xiigeli says there are but three diagnostic signs by which we are enabled to recognize, to any degree of certainty, that molecules under our observation are organisms — spontaneous movement, pro- liferation, and equality in dimensions, united with regularity of form. The most certain characteristic is movement in a straight or curved line — a phenomenon never to be seen in inorganic mole- cules. Multiplication is a character of less importance, because of the liability to adhesion of inorganic or other molecules. ' Granules, of varying size and of a more or less irregular form, ought not to be considered as belonging to the segmented fungi. As to chemical reagents, concentrated acetic acid, which causes all animal tissues to clarify, is without influence on bacteria. Many coloring-stuffs used in microscopic technics are of assistance in diag- nosing bacteria ; among the best of these are hamatoxylin, fuch- sine, and Bismarck brown. The Development of Bacteria. Of all living organisms known to natural science the bacteria are the most widely dispersed : they jnay, in fact, be said to be ever}'where — in the air, water, upon and in solid animal and vege- table bodies. OuiGiN. — The origin of all inferior organisms has ever been a question open to most variable and vital discussion ; but, in general, three ways have been assumed for this most imj)ortant function: 1. By heterogenesis ; that is, by direct production from mineral or organic substances (spontaneous generation). 2. On the rule that ''like bejrets like'' it has been asserted that all bacteria must come from others of the same kind, by one of the recognized forms of generation : fission, spores, etc. 3. Others assume that, while they derive their origin from 86 THE DISEASES OF DOMESTIC AXIMALS. organisms abeadj in existence, tliej represent notliing more than dijfferent stages or forms of development of known species. This latter hypothesis is known as polymorphism. The Dissemination of Bacteria in Ditfekent Media — Air and Water. The experiments of Pasteur, T\Tidall, and others, have clearly demonstrated the presence of vegetable germs in the air which has been allowed to pass through apertures into vessels prepared for the purpose. These germs generally have the micrococcus or microbe form, and are present in lesser numbers in winter than in summer and fall, which fact finds its explanation in the greater degree of vegetable decomposition and telluric evaporation which takes place during the warm months in comparison with the cold. The experiments of Cohn and others have demonstrated that the atmosphere contains very few adult bacteria ; in fact, they are rarely found therein in a complete state, but rather as bright, refracting points, very difficult if not impossible to distinguish from one another. These points probably represent the latent or permanent spore-con- dition of bacterium life, capable of generating into tnie bacteria under favorable conditions. These spores may form the point from which epidemics take their origin, and in this condition are capable of wide dispersion. Nutrition and Respiration of Bacteria. As bacteria have some of the essential characteristics of organ- ized beings — a cell-membrane and protoplasmic contents — they must naturally receive nourishment and respire in the same way as all colorless -vegetables and inferior animals which have no special apparatus for such purposes ; that is, by endosmotic absorption. It matters not in what medium they may be met with, they re- quire— in order to live — water, nitrogen, carbon, and oxygen, as well as certain salts from the mineral world, which enter in very minute quantities into their organism. Water is indispensable to the activity and development of bac- teria. Desiccation, drying out, completely arrests the movement of those that are mobile, and the functional activity of all bacteria. Desiccation does not, however, killthem, unless it is too prolonged, as is proved by the activity retained by the various kinds of virus used for inoculation. In the condition of permanent spores they retain their vitality a long while. It is a surprising fact that the great chemical difference existing between salt and fresh water INFECTION. S7 appears to exert little or no influence upon the development of bac- teria. NiTitoGKx. — The experiments of Pasteur have demonstrated that an albuminoid nitrogenous substance is nut necessary to the life of bacteria, but that other nitrogenous substances, as ammonia, will answer the same purposes. Pasteur's cultivating solution is as follows : Distilled water 100 parts. Sujrar-onndy 10 " Tartrate of ammonia 1 '* Ashes of one gramme of yeast 0075. Cohn's fluid is designed to counteract the development of mold due to the cane-sugar in the above solution, and is as follows : Distilled water 100 parta. Tartrate of ammonia 1 " Ashes of yeast 1 " Mayer gives us another fluid which does away M-ith the ashes of yeast, viz. : Phospliate of potash 0-1 gramme. Sulphate of magnesia 0*1 " Tribasic phosphate of lime 0*1 '' Distilled water 20 c. c. Carbon. — Aside from other sources, bacteria can obtain this im- portant element to their life from organic acids. Oxygen.— ^Numerous controversies have taken place among sa- vants as to the 7'6le tliis element plays in bacterial life. It seems, a priori^ that, like other living things, oxygen must be necessary to germ-life. Pasteur has demonstrated tliat it is not so, however, with all forms of bacteria. In putrefying processes lie has demonstrated that, after certain species have developed />*. termo.^ which depend upon the presence of oxygen, and come to the surface, forming a coating upon it, the fluid beneath is free from this gas, and yet other forms of bacteria come to develo})nient in it. The first of these organisms — that is, tliose dependent on oxygen for life — he has styled aerobic fungi, and the others anaerobic. Other observers do not agree with this theory. Hoffmann, a very able German savant^ says : " These little beings can not live without air — that is, without oxygen. If this gas is wanting, tliey cease to move and to proliferate. If a drop of liquid full of bacteria is 88 THE DISEASES OF DOMESTIC ANIMALS. placed upon a glass slide and covered, the active bacteria will all gradually approach the margin of the cover, and at the end of sev- eral days will be found ah've, while those situated toward the center will be dead." Toussaint, the ablest veterinary student of this subject, has re- cently published the following results with reference to B. anthracis : " The bacteria which occupy the central portion of Kanvier's moist chamber, and which by reason of their situation receive very little oxygen from the groove, are soon arrested in their develop- ment, while those which occupy the borders are long and collect in immense numbers. Those in the center remain small, formed of two, four, or five articulations, which are easily separated. They soon cease to grow, and are not transformed into spores." Cohn, an unquestionable authority, also says that "the com- plete development of bacillus, and, above all, the generation of spores, only take place under the free access of air." Reproduction of Bacteria. "We have already mentioned that bacteria reproduce either by scissiparity — fission — or by the endogenous production of spores, which are again capable of developing into bacteria. We have also frequently mentioned that these spores are so wanting in specific characteristics that it is impossible to assert whether each variety of bacteria has its own specific spore or germinal form, although this theory is mostly supported ; while able authors also hold to a metagenetic theory — that is, that a metamorphosis be- tween the different forms of fungi is possible, the same being due to the influence of the different media in which they may be culti- vated or live. When proliferation takes place by fission, or transverse division of the cell, we see the cell gradually yet rapidly increases in length, the protoplasma in the middle becoming clearer, and a partition forms in the middle of the cell, separating the protoplasma into two distinct portions. The partition is at first very delicate, but soon thickens, and the cell divides in two. This phenomenon takes place more or less rapidly, dependent upon the richness in nutritive material of the media in which it is, on the temperature, moisture, etc. In some cases a constriction takes place in the middle of the cell, the two ends having a figure-8 or bulb-like form. INFECTION. 89 Reproduction by Spores. Until recently multiplication l)y fission "vvas the only form of bacterial reproduction admitted by naturalists. The formation of spores has been observed in bacillus subtilis (Cohn), bacillus anthracis (Koch), and in bacillus amylubacter by another ohserver. In cultivation experiments nuide with hay-infusion we may see, at a certain moment, in the homogeneous filaments of the bacilli, very refractive corpuscles making their appearance. Each of these corpuscles becomes a spore, oblong, or in the form of a short fila- ment, highly refractive, and having well-defined outlines. "We find the spores arranged in a simple series in the filaments. So soon as the formation of spores has terminated, the filaments can no longer be distinguished, and one would say that the spores were com- pletely free in the mucus; but their linear arrangement shows that they are produced in the interior of the filaments. These dissolve slowly, and the spores, being reduced to a fine powder, settle to the bottom of the liquid, where they may be found in great (piantity. The germination of spores does not apparently follow in the same medium; but, if we remove them to a new cultivating fluid, we may observe the spore to swell up and elongate, resembling a bacterium with a head. Soon the head, the most refractive portion of the object, disappears, and the tube stretches into a short rod- bacillus, commences to display motion, and becomes jointed by transverse division. The Action of Bacterlv witu Reference to Contagious and Virulent Diseases. One of the peculiarities of all life is the struggle for existence. Both animal and vegetable life is encompassed by this fact. Indi- viduals of the same kind and those of a different kind all live at the expense of one another. Many perish in the conflict. Life is a constant struggle with death. Even the individual cells of which the organs of our body are composed undergo this constant struggle ; the stronger overcome the weaker. So it is with disease. The germs of infectious diseases on entering the animal organism at once begin a conflict with the elements of the same for nutritious material. If the elements of our bodies are the stronger, they finally overpower these disease-producing enemies, and we live ; if the latter are the more powerful, we die. 90 THE DISEASES OF DOMESTIC ANIMALS. While many forms of fungus-life are known to have an eco- nomical value, which we make practical use of in the production of wine, beer, vinegar, yeast, etc., it is still more important to us, and of no less practical value, that we should know the nature of the action of those which produce disease, either in ourselves or in our domes- tic animals. In both instances we have to do with questions of natural economy, though the directions in which we pursue our in- vestigations are so manifestly different. While much has been written upon the action of bacteria as re- gards their etiological relation to disease, still we are forced to admit that the subject is yet buried in the greatest obscurity. We find it a hard task to distinguish the essential from the unessential in our studies. The task we have before us is, then, to discuss the role which bacteria play in the generation of disease in the animal kingdom. The diseases w^iich have been attributed to germinal action are very numerous ; in fact, the list includes all the infectious and con- tagious diseases, and many of a questionable character. Some en- thusiasts (Hallier, Zurn, and others) have even professed to discover the specific germ in every case, and we have in their writings most explicit descriptions of the peculiar fungi of glanders, cholera, hay- fever, rinderpest, and numerous other diseases, observations which the most exact experiments of other equally proficient authorities have failed to confirm. While our knowledge of specific disease-producing bacteria is thus limited, we can safely assert that, with increasing years and consequent improvement in the means and methods of investiga- tion, it will be constantly extended and augmented. It is well known that there are forms of fungus-life which live upon plants. A peculiar fungus — ustilago maidis — is the specific cause of the rust of grain. It is also known that during one period or form of its existence, this fungus lives upon the leaves of the barberry-bush ; and practical experience, based on this knowledge, has proved that with the removal of these bushes in certain districts the sequential disease of corn has ceased to appear. A very important question is, Are the infectious elements of disease of a gaseous nature, or are they organisms ? We know from experimental experience that a very small quan- tity of infectious material is necessary to produce certain diseases. We also know that, when in case of a certain disease (anthrax) we introduce the smallest quantity of material into the organism, a mul- tiplication of this material takes place. INFECTION. 91 We know that the disease-producing germs arc capable of suspen- sion in the air, thereby impregnating it with tlie property of infection. If we phiee healthy cattle in the same stable with others afflicted with contagions plenro-pneumonia, we know that they will probably ac(piire that disease, even though none of the healthy may be placed in direct relation with the diseased ones. The same has often been found to result when healthy cattle were placed in a stable where the disease had been, and the sick and all others in it at the time had been removed and some attempts at disinfection taken place. I shall relate circumstances which will sufficiently prove that cattle in the same stable with others having tuberculosis have acquired the disease, and that by means of the aspired air. Of our own species we know that it is only necessary for a sus- ceptible pei*son to be in a room for a few moments with an indi- vidual afHicted with the measles, scarlatina, variola, exanthematous typhus, to acquire these diseases, or to live for a short time in a cer- tain malarial district, to acquire either the yellow fever or intermit- tent fever. These examples sufficiently demonstrate the infectious nature of the atmosphere at certain times and in certain localities. While this is a fact, still the most contradictory views are entertained, both by the medical profession and the public, as to the real nature of the infectious elements. "We find our medical writings constantlj'^ mentioning " volatile contagiums," or " gaseous miasmas " — things which do not exist, and are entirely in contradiction with the results of modern research. AVe can speak of the infectious elements as fixed, or movable ; that is, such as nuist be attached to some vehicle, be it a living or- ganism or something polluted with the excretions of the same, or such as are easily taken up by the air and transported to some dis- tance from the place of generation. But neither of these definitions corresponds to our ideas of a gas. A poisonous gas when suspended in the air is more or less widely dispersed, and soon loses its activity. If it enters the body, it must enter in certain quantities, or no evil action follows. We know of no means by which it can multiply itself within an organ- ism. On account of their liability to disjn'rsion, it is almost impos- sible for an organism to inhale enough of a poisonous gas to cause serious disturbance in the open air. The gas and person must be confined in a room, and a given quantity inhaled, before evil con- sequences result. Even though a person may inhale a considerable quantity of such gas, removal from it soon relieves its effects. 92 THE DISEASES OF DOMESTIC ANIMALS. As many of you may have read, in tlie Catacombs of Rome and other such places carbonic- acid gas is generally very abundant in the lower strata of air in the passages, and while it is impossible for dogs or cats to follow their owners in such places, yet the latter, on account of the greater elevation of their respiratory apparatus, can walk along in perfect safety. We know also how quickly un- pleasant odors are dispersed by the atmosphere. A poisonous gas must be very soon so dispersed as to lose its specific characteristics. Were the generation of cholera dependent on infectious gases, we should find it rapidly extending over every part of a city or dis- trict, instead of being confined, as is frequently the case, to certain streets or districts. So in the case of rinderpest. If the infectious elements were of a gaseous nature, our endeavors at stamping out would be utterly futile ; yet we know we can frequently confine it to a single stable in a village where many cattle are kept. Were the infectious elements gases, all individuals with any disposition to infection would contract given diseases, as they would be far more likely to take up a correspondingly equal amount of infectious material than if they were of an organized nature. Again, if they were gases, the infectious elements would soon be so widely dispersed as to lose their activity. While we know the minuteness of many forms of bacterial life, so minute that our strongest powers give us but the most inadequate idea of their nature, may we not safely assume that there are many forms which still escape our observation ? Are the elements of infection formless, or are they organic in- dividuals— that is, objects having form and life ? We have two possibilities to consider : either they enter an or- ganism in such quantities as to cause immediate action, or they enter in very small quantity, and have the power of multiplying within the organism. By poisoning the first takes place. A given quantity of a known poison causes direct and specific action. This never takes place by infection. Specific poisons have no period of latency. The most poisonous of substances act only in this manner. Minus a given quantity, no poisonous action, though we may have what is known as a physiological or medicinal action which we make use of in many of them. If we carry these medicinal doses beyond a cer- tain limit, a poisonous action frequently results, which is known as the cumulative action of drugs — as with strychnine. INFECTION. 93 While a given, appreciable quantity of poison is necessary to specific action, we find in infectious diseases the contrary to be the case. We can not appreciate the niinutcnc.-is of the quantity of in- fectious element necessary to produce an infectious disease. A single bacterium, in a condition of active proliferation, can lead to the development of anthrax, if inoculated into a susceptible or- gimism. Who would have temerity enough to introduce under his skin even the smallest part of the point of the finest needle which had been di[)ped in the saliva of a rabid dog? Yet we can neither Aveigh nor otherwise appreciate the quantity of the inficieus introduced. You need no further proof of the impossibility of unformed elements causing infection. Unformed elements have not the power of self-multiplication. We are, then, naturally driven to the assumption of organized elements, as the etiological momenta in infection. The elements of infection must have the faculty of multiplica- tion. They must have the faculty of taking up soluble nutriment from their surroundings. What, then, must be the real nature of these elements? Our studies and experiments have clearly shown that, of all organic life, but one form has the characteristics which conform to these con- ditions. That is the bacteria ; or, more particularly, the schizomy- cetes, or fission, spore-producing fungi. These fungi correspond in every particular with our theories. They are small enough to be taken up in numbers, under favorable conditions, and widely dispersed by the atmospheric currents. They possess the ability to multiply to an incredible degree, doubling their numbers, under suitable conditions, in a few minutes. Their te- nacity of life exceeds that of any known objects. AVhile the essential characteristics of the bacteria in question so fully conform to our hypothesis, our practical experiences are not so full of assurance. AVhile, in some few diseases — diphtheria, intermittent fever, an- thrax, and emphysema infectiosum — we find the fission-fungi or sj>ores present in great numbers, in other hypothetic germ-diseases they are frequently wanting, or very seldom met with. AVhile we must admit the meagerness of our knowledge as to the manner of life of these bacterin, yet we may a.isume that their deleterious action extends itself in three directions. While the infectious elements act in the smallest quantities in the purely contagious diseases, when introduced into a suitable or- 94 THE DISEASES OF DOMESTIC ANIMALS. ganism, experience seems to justify us in assuming that much greater quantities are necessary with regard to the so-called malarial diseases. Miasmas are not transportable in the sense of the infectious ele- ments of purely contagious diseases. We can not acquire intermittent fever at any time or place, but must be in localities where it is generated. In septic diseases, we have, fortunately, still another condition. The continued introduction of infectious material is necessary to produce septictemia ; for experience has taught us that if, by disin- fection of the wound, we can shut off the supplj', even though the wound continues, we may prevent the general disease. We know, further, that we can introduce, subcutaneously, no inconsiderable amount of septic material into a rabbit, without causing fatal re- sults ; but, if we continue the supply, the general disease, blood- poisoning, follows. We do not know why it is that one individual of a given species is susceptible to infection by a contagious disease, and another not ; or why at one time an individual may become infected and at an- other not ; or why at one time we may go to a locality where inter- mittent fever or yellow fever prevails and not become diseased, while at another time we may acquire either of them. In fact, when we come to the earnest study of the causes of con- tagious infections, as well as malarial diseases, we become more and more convinced that our ignorance far surpasses any knowledge that we may possess. Dispersion of Bacteria, and their Entrance into the Anenial Organism. The deeper we seek to penetrate into the life and functions of the bacteria, the more do we feel ourselves as lost wanderers upon an unknown sea. We find very few known facts to cling to, as rocks of refuge to the storm-tossed mariner. There are but few beacon- lights along this coast. There are no more important questions in connection with bac- terial life than as to the means by which they become separated and dispersed from the original places of generation ; and, again, how they enter from these into the animal organism. Notwithstanding our poverty of knowledge, we have still some points of practical value at command to aid us on our way. We have ail-sufficiently established the non-gaseous nature of the elements causing contagio-infectipus diseases — a fact which will become still more apparent as we pursue our studies. INFECTION. 95 In all strictly contagions diseases, yon Avill remember, the ele- ments of infection are always generated witliin the diseased organ- ism, and pass off with the excretions, or are attached to them. In miasmas they are always generated ontside of any animal organism. This distinction mnst never be lost sight of. It is trne we have infections diseases, in which, originally, the etiological elements are generated ontside the organism, and which have a certain degree of contagiousness by means of their excre- tions. This is tiie group of infcctio-contagious diseases of which febris tlava and anthrax are examples. AVherever infectious germs are produced, their generation is based upon the 2>i'esence of moisture, either as a watery fluid or some substance containing moisture sufficient to the purpose. We find no difficulty in comprehending the dispersion of infec- tious elements when they are still contained within or upon the ma- terials where they have been generated, that is, by means of streams, or of solids or fluids impregnated with them. Distribution or disper- sion of infectious stuff in this way is by no means the rule ; in fact, it is seldom that it takes place to any distance, unless artificial means come into play. Glanders, variola, and syphilis can only be ac- quired by direct contact with an infected organism, or with a vehicle which has been polluted with the specific elements of either of these diseases. Only the infectious elements — inficientla — of purely contagious diseases are capable of any wide dispersion, and this can only take place through the moving of diseased individuals or the transport of derivatives from the same — clothing, excretions, hides, horns, hair, etc. — or through accidental substances which may have become impregnated with excretions from them. Elements of infection can only be dispersed in two ways : 1. By means of water or fluids, or moist substances containing them. 2. By the air, or in some desiccated vehicle or condition. Infectious elements do not long retain their original condition and activity in water. The nature of the nutriment found in such media exerts a corresponding influence upon the nature and activi- ties of genns. Metamorphosis into non-malignant forms is fre- quently said to take place. In jiure spring or rain water they soon demonstrate changes for ■want of sufficiency of nutriment. They retain their specific char- acteristics longest in those media in which they are originally gen- erated. 96 THE DISEASES OF DOMESTIC ANIMALS. The excretions of purely contagious diseases conform more to this condition than external media ; but when these are exposed to the action of an excess of moisture, decomposition of the media and germinal changes soon follow, which are opposed to further con- tagion. We are justified in asserting that contagions which are sup- ported in moisture not their natural media soon lose their activity. Such disturbance takes place more rapidly in a warm than in a cool temperature. The more water a given medium contains, the poorer its nutri- tious qualities, and the quicker destruction or change takes place upon germs suspended in it. In a frozen condition media as well as germs suffer but little change. Distribution of infectious elements in a desiccated or dried condition takes place either by means of the atmosphere, or upon the surface of or within desiccated vehicles. The elements of infection retain their vitality longer in a desic- cated condition than when in or upon media of a moist nature, or when the desiccation takes place with sufficient rapidity to prevent decomposition or changes in the media, or the germs in or upon it. If the processes of desiccation take place with such a rapidity and to such a degree as to remove all moisture, the germs perish. Some degree of moisture is necessary to their vitality. Germs re- tain their activity longer in a cool, moist atmosphere than in a warm and dry, and less long when suspended in a dry atmosphere than when contained in a dry substance, where they are protected in some measure from further desiccation. We know that the transportation of infectious elements to any great distance by means of the atmosphere does not take place, but that they may be trans- ported a long distance by means of diseased individuals or infected vehicles. From what has been said you must infer that infectious elements are largely transported by means of the air or desiccated objects, and that these are the chief sources whence to gain entrance to the animal organism. Infectious elements must be generated in media containing moisture. They are not volatile — gaseous — and must first become desiccated and reduced to powder before they can be taken up and transported by the atmosphere. Some authorities have mistakenly asserted that the germs are, as it were, torn away from their moist media with the molecules of water which pass off with evaporation. That this is false is proved by the evaporation of salt water. The salts remain ; the volume is INFECTION. f)7 less, but the quantity of salts is the same. TVhere vro find salts suspended in the air, there has been sufficient mechanical action not to remove molecules of water, but to take it up in drops, as in a storm at sea. With the cessation of the storm the salts drop of their own weight ; but evaporation does not cease. JBacteria can not be removed by simple processes of evaporation ; small as they are, they are larger and heavier than the molecules of salt dissolved in water. Infectious elements can only be taken up and transported by the atmosphere when in a dried or dust form. Two important adjunct circumstances come also into considera- tion in this regard : 1. The degree of adliesion with which such elements cling to their place of birth or lodgment. 2. The mechanical means to which they are subjected. "With reference to the latter, the most simple case is where the dried mass, or the remnants of an evaporated fluid, are disturbed or ground to a powder by some mechanical means which renders it easy for the atmosphere to remove them. The formation of dust in our streets, which may frequently con- tain bacteria, and its removal by the wind, is a fitting example. To this end it is essential that the material which contains the germs does not contain anything of a mucilaginous or adhesive nature, and that the particles of the same are sufficiently small. The dissemination of a gas takes place very rapidly in the at- mosphere. Even though the movements of the latter be imper- ceptible, a bad-smelling gas soon disajDpears if the supjjly be cut off. The distribution of dust is dependent on its fineness and the vio- lence or force with which the air moves ; but in no case is it capa- ble of very extended dispersion. In a motionless atmosphere dust molecules or germs soon fall to the ground. The smaller tliey are, and the more rapid the movement of the air, the longer they are kept in suspension. So many circumstances are necessary to the dispersion of in- fectious elements by means of the atmosphere, it is evident that they may be confined for a long time to an individual, a house, street, or locality. An organism is, therefore, so much the more exposed to a given infection, the more it is confined to a locality where infectious ele- ments are or have been generated, or the more the air-currents come from such a place. Infections elements do not all possess the same degree of dis- 1 98 THE DISEASES OF DOMESTIC AXIMALS. persion ; so that, under otherwise similar cirisumstances, one disease may attack a far greater number of individuals than another. The Infection of the Animal Organism. Here, again, we find ourselves mostly upon a hypothetical foun- dation. All is not gold that glitters ; so it will be with many of the existing theories of fungi-infection ; but out of all we shall finally winnow many facts. The penetration of germs into the body by means of an intact outer cuticle may be looked upon as impossible. Whether they can also penetrate through the mucosa, and walls of the capillaries of the intestinal or respiratory tracts, is also very questionable. In anthracis pulmonum, a condition of the lungs due to the pres- ence of coal-dust in the finest form, we find it accumulates in the alveolae, but we find no proof of its gaining access to the circu- lation; the same is true in the so-called "grinder's pneumonia," which is due to the presence of stone-dust in the lungs. In the intestinal canal we know, from our physiological studies, that even the finest qualities of solid fats are incapable of absorp- tion ; the action of the gall and pancreatic fluids is first necessary, by which they are reduced to an emulsion. We are not, then, justified in assuming that bacteria gain access to the living organism, either on account of their minuteness, or in any passive way. Action on the part of the bacteria themselves must play no secondary part in this phenomenon. To a passive entrance, or in fact to any entrance into the living organism, the respiratory tract offers by far the most favorable op- portunity. As may be known to many, the capillaries of the lungs are of an extremely delicate nature ; they also dip into the alveolae ; that large number of bacteria are taken up with the aspired air seems very probable ; that very few, even in a profusely impregnated atmos- phere, gain access to the air-cells of the lungs, must be also true ; for the mucosa of the respiratory tract extends from the entrance of the nostrils to the beginning of the inf undibula, or conglomerate of air-cells. The alveolae themselves have no mucosa. The viscid nature of the covering of this membrane is of such a quality as to warrant our assuming that the major part of such germs are caught by it, and gradually find their way back to the pharynx by means of the ciliary movement of the tracheal and bronchial epithelium. INFECTION. 99 AVe know that the fission-funyi liave a boring movement, and that this is apjnirontly in a forward direction ; the question is, Is it strong enongh to penetrate these tine capillaries ? The answer is, AVe do not know ! Again, some authorities have described openings, or vacancies, between the individual epithelium cells lining the alveoli, and have looked upon them as the endings of tlie pulmonary lymph system. If such stomata or openings really exist, they offer a natural and favonible atrium to the ])enetration of bacteria into the system by means of the lungs. As we have said, but a very small number can certainly pene- trate so deeply as the alveoli ; but we know that, on account of the wonderful degree of proliferation, a very small number is sufficient to produce infection. The blood, from its chemical composition, and the presence of oxygen, united with the temperature of the body, offers the most favorable condition for the multiplication of bacteria. As to the intestinal tract, we have already said that the nature of the mucosa is such that we do not believe it possible for the bac- teria to penetrate its different metnbranes. The acidity of the stomach offer's very unfavorable conditions to the life or multiplication of germs. Some have assumed, and among them the ablest of mycologists, that an abrasion (wounding) of an intact surface is necessary to the entrance of bacteria into the system. AVhen we reflect on the mi- nuteness of these objects, and how frequently results of this nature may take place, both in the respiratory, and particularly the digest- ive tract, we tind good grounds for accepting this hypothesis as the one favoring the general way in which infection takes place. Slight abrasions of the mucosa of the nostrils, pharynx, cheeks, etc., or even that of the tesojihagus, stomach, and intestines, are very common with our own species : how much more so in our domestic and other animals which seek their food in a natural manner, or re- ceive it from the none too careful hands of man ! An unhealthy mucosa is of itself seldom intact ; abrasions of its epithelial covering are very common, even though they do not occa- sion sucli disturbances as to lead one to suspect any very serious trouble. The proneness of the niminantia to take up all sorts of foreign objects — nails, hair-pins, broken glass, and even knives and fork? — is well known to many. Traumatic inflammation of the stomach and heart are no uncom- 100 THE DISEASES OF DOMESTIC AXIMALS. mon diseases in our cows, especially such as are grazed on road-sides and house-yards. Traumata, wounds in the cutis, are very common among our animals, and much more so among grazing animals, especially on the feet and legs and around the hoofs ; and as these parts are fre- quently in places where germs would be abundant (marshes, etc.), they offer the most favorable atria to the penetration of germs. How do germs act ? By depriving the body of nutritive material, by obstruction, cap- illary embolism, and by the products which either of themselves, or by the disease-processes, are induced by them. That they require large quantities of oxygen has been made ap- parent ; and it is self-evident that, on their entrance into the body, there must be a constant struggle with the red blood-cells for this necessary gas. Whether they produce carbonic-acid gas (COj), and thus add to its accumulation in the system, is still an open question. That capillary embolism is possible has been too frequently ob- served to be questioned. This condition would be but another way by which parts, not the whole, of the system, are shut off from oxygen and other nutritive material. Infectious diseases do not seem to last long enough to cause ne- crosis, or necrobiosis (death), in parts thus shut off from the circula- tion ; at least, never in my reading have I met with any description of phenomena similar to those we meet with in ordinary embolism. When an organism withstands the invasion of an infectious dis- ease, we may assume that it offers no longer a favorable condition to the bacteria ; they die, suffer some sort of a dissolution, and are passed off as an effete material. Disinfection. The birth of crude empiricism may be asserted to have been coeval with the first realization of pain or suffering on the part of man. The aim of modern medicine is prevention. We are ear- nestly endeavoring to make practical the old saying, " An ounce of prevention is worth a pound of cure." The men who boast of their " cures " are slowly becoming less numerous among the true practitioners of medicine. As observers slowly came to the idea that one disease, and then another, was due to some inficiens ; that many such diseases were strictly or partly contagious — that is, passing directly from one ani- mal organism to another — they began first to take means to prevent them : hence restrictions of commerce, not only with regard to hu- INFECTIOX. 101 man beings, but animals and their products. This restrictive, pre- ventive medicine, if we may be allowed the term, has been rewarded by the grandest results, though it at first paid little or no attention to the primary causes of the diseases it sought to prevent. The causes it recoy:nized were those of intercourse and commerce. It sought to regulate these with reference to the contagious diseases, and the result has been that the black-death and bubo-pest have become entire strangers to Western Europe ; Asiatic cholera is no longer the terror of the civilized world. Aside from the benefits of vaccination, the varioliB no more carry horror into the human family. The cattle-owner of Europe does not awaken on any morning and find the rinderpest devastating his herd. The lung-plague of cattle is kept within restricted limits, and so of other diseases of like na- ture. Tliese remarks have no relation to diseases of a purely malarial character, which are based on locality. Here we have to do with questions of drainage, tillage, and the like, which we will not dis- cuss at present. "While this work of modern medicine is of no secondary impor- tance, the results of the observations and experiments of recent years have opened still another path to the workers in preventive medicine. They have discovered the causes of some diseases, and gained knowledge that justifies us in assuming that the causes of all infec- tious and contagious diseases are of a similar nature. This cause is the schizomycetes or fission-fungi, and their germs, which bear the general name of micrococci or microbes. Having discovered these objects, the next step has been to study their mode of life, how they live and multiply, what elements favor these processes, and what are opposed to them. Our conceptions in this regard are still far from clear, and too frecpiently our action is based on mistaken reasoning. We too often think that, when we have removed the odor from an offensive place or substance, we have destroyed its disease-pro- ducing qualities, a hope which is only too soon negatived by expe- rience. The resistibility of germs is such that we may look upon it as very nearly fallacious to disinfect the atmosphere by adding to it chlurine-gas, or sulphur, or any similar disinfectants. Such disin- fection is more or less an idea inherited from the earlier days of preventive medicine, and not in conformity with our present knowl- edge. 102 THE DISEASES OF DOMESTIC ANIMALS. In considering the question of disinfection we must ever bear in mind that the fission-fungi, or their spores, always occnr in one of two conditions ; that is, moist or dry. This fact should always be settled before we decide as to our disinfecting procedures. When in a moist medium, bacteria are much more easily destroyed than when united with a dry. If we meet with them in a fluid, a boiling-heat is necessary to their destruction. Temperatures of 77° to 10^° Fahr. are in general favorable to bacterial life. The most advantageous has been found to be 95° Fahr. The resistibility to high temperatures varies in the different bacteria. A temperatui-e of 113" to 122° Fahr. has been found sufficient to kill bacteria thernio, while bacilli have been found to resist 176° Fahr. Extreme degrees of cold are far less effective to their destruction than heat. We have too often assumed that when our antiparasitics, or, better, antiseptics, have prevented the fermentative processes, the germs have been destroyed also. "While heat is the most effective of all the disinfectants, we shall make no mistake in adding to it those chemicals which are at enmity with bacterial life. Nageli sums up his remarks on disinfection as follows : 1. The infectious elements can not be securely destroyed when in an absolutely dry condition. 2. Boiling-heat can only surely kill them when they are in a moist or fluid medium. 3. The antiseptics which have gained acceptance are not posi- tively death to them ; they only place them in an inactive condi- tion, that is, consume them. (This argument is open to the objec- tion that, in disinfection, the disinfectants have been, or have to be, used in too diluted a condition, or in such a way as not to come either directly or in sufficient volume in contact with the bacteria. This last must nearly always be the case in spray or smoke disinfec- tion, which we believe to be an illusion.) 4. They are changed, not destroyed, by decomposition of media, by means of a surplus of water or heat, so that they lose their infec- tious properties. 5. They are harmless when removed in a moist condition. The true value of the internal application of the antiseptics is of a very questionable nature ; for these materials exert fully as poi- sonous an influence upon the autositic as the parasitic organism. In some cases, as in intermittent fever, it would seem as if we could bring the organism so under the influence of quinine as to act against the proliferation of the spirillum. That this bacterium dis- INFECTION. 103 appears in the intervals of tlie fever has been mentioned. AVhere it comes from a^ain during the paroxysms is an open question. AVhile this may be true, in a measure, of quinine, boracic acid, and some other materials, the internal use of the stronger antisep- tica in suthcieut volume is too dangerous to be tried. A special study of the antiseptics would lead us too much into details for our present purpose, and I must refer my readers to the works uptm that subject; among the disinfectants are the corrosive acids, carbol, tliymol, boracic acid, hypermanganate of potasli, the coal-tar preparations, and the long list of antiputrids. AlfTIIRAX AND AnTHRACOID DISEASES, The word anthrax is of Greek origin, and means a coal. Tlie name wjvs not originally given to a single disease, but to a group of diseases which were characterized by a black, tarry appearance of the blood. In any form, the blood is essentially complicated, while all the organs of the body are more or less aifected. Modern research has led to the isolation of one disease from this group as anthrax. The others may be called anthracoid (i. e., anthrax-like) diseases. They are all germ-diseases ; but the germ which has led to the isolation of one disease as anthrax has singular characteristics in its mature or bacterial form which enable us to distinguish it from other almost similar bacteria. The disease is also known as charbon (carbuncle), Milzbrand, etc. Jlisiori/. Of all the pests, or infectio-contagious animal diseases, anthrax seems to be the one of which we have the earliest historical rec<»rd. Moses has apparently described it as one of the plagues by which Jehovah punished the Egyptians. The early Greek and Roman writers mention it under the names of sacer ignis ; gutta robea ; also by its present name, and it is also mentioned by Arabic writers as " Al Immrah'' or '* Persian fire." Charbert was the first author to enter into any clear and criti- cal study of the various diseases of this group, and published a work, " Description et Traitement du Charbon," Paris, 1780, which even at the present day exerts more or less influence, especially in France. Although the observations of the eighteenth century led many authors to declare for the contagiousness of anthrax, still others declared it to be non-contagious. Kausch, an author early in this century, gave a good description of the pathological changes of this 104 THE DISEASES OF DOMESTIC AXIMALS. disease, and looked upon it cliieflj as a paralysis of the pulmonary nerves, but declared himself for the infection of man and animals by means of the blood, flesh, etc. Delafond, 1843, studied the disease among sheep ("Maladie de Sang"), and looked upon the abomasum and intestines as the chief seats of the disease, and declared it to be an acute enteritis by which the blood was also complicated. He denied the infectious character of the disease, and sought its etiology in hyper-nourish- ment, and in abnormal chemical changes in the earth. Gerlach 1845, looked upon this disease of sheep as identical with anthrax, and proved its infectiousness by direct experiment, and considered the contagium to be volatile aud having great tenacity. Heusinger, in his noted historical work upon " Animal Plagues," looked upon the disease as a malarial neurosis, and assumed that the infectious elements acted chiefly upon the ganglionic nerve-centers. The primary changes consisted of a paralysis of the blood-vessels of the spleen and the consequential death of its tissues, hence its German name, " Milzbrand " ; following this, the disease is charac- terized by vascular jjaralysis, blood-stasis, extravasations, and necro- sis in different organs. Contagious elements are developed by the disease, which lead to its extension. These elements are taken up by the lymph and blood-vessels, chiefly the latter, from the parts primarily complicated. The apparent divergence with which the disease manifests itself in different animals is not essential, as the essentials of the disease are nearly the same in all. The disease de- velops primarily in grazing animals, solipeds, ruminants, and swine. All animals are open to infection. In 1855 Virchow followed Heusinger in declaring for the mala- rial nature of the disease ; he emphasized its septic character, and looked upon the cause as a specific ferment. "Wald, 1862, laid spe- cial emphasis upon the nature of the soil in the generation of anthrax. In 1856 Pollender broke the ground which has gradually led to our modern views of the true nature of anthrax, and its isolation from kindred diseases; so early as 1849 he had found peculiar staff- like bodies in the blood of anthrax-diseased animals. Entirely inde- pendent from the observations of Pollender, Brauell, professor at Dorpat, Russia, found (1857) the same microscopic elements in the blood of men, sheep, and horses that had perished from the disease. He looked upon them as vibrios, and as he found them intra vitam (during life) in the blood of such animals, considered them to have diagnostic value, while Pollender declared their importance to be still an open question. INFECTION. 105 The discovery of tliese two observers gradually drew the at- tention of scientists to the study of this disease, and it may be truly asserted that no single disease has enjoyed so much observation in modem or ancient days. By means of a succession of experiments Brauell came to the knowledge that the peculiar staff-like bodies appeared from one, two, or three, and in some cases eight to ten hours before the death of the diseased organism, and when the course of the disease was very acute, but a few moments before its fatal termination, while they were not to be seen in the blood of convalesents, lie credited these objects with a ])rognostic and diagnostic value, but denied to them any etio- logical importance, as the disease could be produced with blood which did not contain them, a fact which will find its explanation later on. These peculiar bodies were not looked upon in the same light by different observers, some considering them as coagaluted fibrin (Briickmiiller, "Zootomie- Pathologique"), fragments of broken- down tissues, blood-crystals, while Delafond looked upon them as a species of leptothrix. In 1S60 the last-named author adopted the views of Brauell. In 1803 Davaine declared these bodies to be bacteria, and, in order to distinguish them from the motory bacteria of putrefaction, gave them the name of hacterklicn. As the blood without them was not infectious, he declared them to be the specific cause of this disease. The bacteridii\} are destroyed by putrefaction, but may be preserved for a long time in a desiccated condition. After this time, there followed a period of the greatest diver- gence in the views of different observers as to the true nature and place of these objects : all sorts of things — blood-crystals, the bac- teria of putrefaction, the cent-like rolls of the blood-cells, etc. — were declared to be the same as the bacteridiiB. Davaine's work, more than that of any other author, gradually led to the production of order out of this chaos. He found the bacteria to be present in the majority of cases of anthrax, antion of the life of these germs, which may not be out of place here, notwithstanding all we have previously considered : " At first the bacilli were absolutely motionless — they had been taken from the spleen of a mouse — but in some cultivations, after keeping them in a temperature of 33° C. for a few hours, a great number of them began to move actively about the field. While at rest they were not altogether without change, for clear lines across them indicated that they were in the process of division 110 THE DISEASES OF DOMESTIC ANIMALS. into segments. Sometimes a number of rods ceased moving, and, previous to lengthening out into filaments, arranged themselves into patches of zooglea. " The division into two or more segments is not always a very rapid process. A rod, which was watched until it divided, was made up of three segments, and one of them from the beginning looked as if it might separate itself from the others ; but after six hours of ahnost constant endeavor, it was still connected by a very delicate thread, and before final separation, which took place after seven hours' observation, it was divided into two segments in a com- paratively short time, so that, when it did escape from the other ap- parently inactive pieces, it moved about the field of the microscope like two freely movable links of a chain. "After assuming this motile phase for some time, the rods lengthened out into spore-heaving filaments. " The lengthening of the rods into filaments is an extremely rap- id process, and is apparently affected by the temperature. In five hours, at a temperature of 32° C, a rod may have increased so as to be from eighty to one hundred times its original length, and in twenty-four hours the filament may be full of spores. If the tem- perature be kept at about 28° C, the spore may not appear until the thirty-sixth or fortieth hour. When the spores have once ap- peared, all the other changes go on at an ordinary temperature of from 12° to 18° C, but not nearly so rapidly, even when the prepa- ration is kept in the sun for a few hours daily, as when artificial heat is employed. On the other hand, a high temperature, 37°- 40° C, at once checks all development. " The filaments, when first formed, are perfectly hyaline, but soon the central protoplasmic contents can be distinguished from the gelatinous-looking sheath. The protoplasma next divides into nu- merous short pieces about the size of the original rod out of which the filament was formed. These contract, leaving clear empty spaces between them, and often again divide to form still shorter masses of protoplasm. " At each side of this transverse line of division minute clear specks appear — the first indication of sjDores. These gradually in- crease in size and luster, and as they increase the protoplasma dis- appears ; in fact, the spores seem to be developed from the proto- plasm. Soon after the appearance of the spores the filaments seem to be made up of numerous segments, each segment containing one spore, the spores lying at the adjacent ends of the segments. The spores now begin to escape. The filament gradually disappears, and INFECTION'. Ill the spores appear surrounded by a mass of gelatinous material. The spores, when free, according to previous observers, develop into rods. My own observations lead me to believe that the spores do not always at once grow into rods, but that they may divide into four sporules, in which the envelope as well as the spores take part. The spore then elongates, becomes dumb-bell sha}>ed, and finally develops into rods." The action of the bacteria within the autositc is, as we have said, the consumption of oxygen, for which they have a great affinity, and the production of CO,. This fact, the absorption of O and ac- cumulation of CO,, would seem to account for those cases of sudden death by anthrax, and for the symptoms by which the disease mani- fests itself — such as dyspnoea, cyanosis, clonic spasms, distended pu- ])il, falling of the temperature, and asphyxia — which all correspond with the phenomena of poisoning with CO,. The necroscopical re- sults corrcs}:)ond to the same : congestion of the venous system, a dark, tar-like condition of the blood, extravasations, cyanotic col- oring of different parts. A peculiar diagnostic characteristic of bacillus anthracis is the abruptness with which each segment terminates : the ends are square, as if cut off, a condition which has not as yet been observed in any other bacteria, not even B. sultilis, which resembles it very closely in every other particular. The tenacity of B. anthracis is very great. They may retain their virulence in a desiccated condition for months or even years. 10^ DQ of a drop of blood has been found sufficient to cause infection. Davaine has caused infection with blood that had been kept in a dried condition for twenty-two months. Bollinger sums up his conclusions as to the nature of anthrax as follows : " It is an acute infectious disease. The infectious elements con- stitute a vegetable parasite, which generates (endogenous) within the infected organism, and perhaps externally (ectogenous), that is, in the earth, when it finds conditions favoralde thereto ; that is, when the earth has been first impregnated. Tiie disease is not contagious in the general acceptance of the word, as infection from animal to animal directly seldom takes place ; but it is highly transportable by means of vehicles, from the peculiar characti-ristics of its etiologi- cal elements. AppeajHUxce and Kctn.^iov. Anthrax occurs in all countries and climates, though to what extent it appears among the animals of this country we have no definite knowledge. 112 THE DISEASES OF DOMESTIC ANIMALS. In making a diagnosis as to whether a given disease is anthrax or not, it must always be borne in mind that no bacillus anthra- cis, no anthrax ; when, in doubtful eases, you can not decide, in- oculation experiments will always give you the key to a correct diagnosis. In 1864, 72,000 horses died in Russia alone from the disease. In the province of Novgorod (Russia), from 1867-'70, over 56,000 horses, cattle, and sheep, and 528 men, perished. Phenomena of the Disease. The disease, in general, presents itself under one of three forms : 1. The apoplectic form (anthrax acutissimus), the duration of which varies from a few minutes to several hours. 2. The acute form (anthrax acutus), the duration of which varies from a few hours to some days. 3. The subacute form (anthrax subacutus), which includes all cases of longer duration. Great divergence exists among the various authors as to the duration of the period of incubation in anthrax. In some cases the appearance of the symptoms of the disease seems to follow imme- diately on the introduction of the inficieus. Fever has been ob- served within two hours subsequent to inoculation. Among cattle the incubation may continue for four or five days ; in small animals, rabbits, etc., twenty-four, thirty-six, or forty-eight hours ; seldom three or four days. On account of the variance in form with which the disease appears, it is difficult to give any concise description of its phenomena. In the so-called apoplectic form the infected animals frequently drop, almost as if struck by lightning ; they fall into convulsions, dyspnoea, cyanosis, and in a few minutes death results. Frequently, these violent symptoms are wanting in all prodromic phenomena, the animals eating and appearing apparently as well as ever. It is not unfrequent to find animals in the morning dead in the stall which were apparently perfectly healthy the evening before. The acute form of the disease appears about as follows in horses and cat- tle : Animals apparently healthy suddenly develop a loss of appe- tite ; in cows, the milk secretion is restricted, or ceases altogether. The animals begin to tremble, and frequently chills may be seen to be present ; the superficial parts of the body become cold. This cold stage passes into a febrile, after a longer or shorter period. Peculiar contractions and clonic spasms of the extremities are quite frequent. During the remissions the animals appear weak and de- INFECTION. 113 pressed, or tliey may be apparently quite well and ruminate, and take to feeding. The pulse is increased to double its normal rapidity ; the tem- perature rises from 41° to 41'7°C. The excrements are frequently tinged witli dark blood, or are bloody and diarrhoea-like. These symptoms are not constant, but are interrupted by remis- sions, -svhich may continue from six to twenty-four hours, during which the animals often appear as if quite well again. Aside from the aix)plectic and acute forms of the disease, we have a subacute and exanthematic form, in which we meet with a carbunculous and erysipelatous tumefaction distributed over differ- ent parts of the organism, especially on the posterior extremities. These tumefactions are generally hot, and more or less painful. The general habitus of the animal seems to suffer but little change. Re- sorption of the exudations soon begins, and it is not very frequent that we meet with excoriation and ulceration. From sixty to seventy per cent of the cases of anthrax in horses and cattle end fatally, and are characterized by the above-mentioned phenomena — dyspnani, cyanotic condition of the different mucosae, opisthotonic condition of a variable intensity, spasms of the musculi palpebrarum, so that we can only see the whites of the eyes ; the animals become extremely weak and are unable to stand ; the tem- perature falls below normal ; the extremities become cold, the pupils distended, and death appears, under the ]ihenomena of asphyxia, in from twenty-four to forty hours from the tirst ai)pearance of the disease. In favorable cases, the recovery is very rapid. The carbuncular formations in the cutis are much less frequently met with in cattle than horses ; otherwise, the symptoms of the disease among horses offer no essential differentiation from cattle. The intra-vital phenomena of anthrax in the smaller domestic animals are far less distinctly marked ; however, we meet with con- vulsive phenomena, dyspnoea, and mydriasis. Pathological Anatomy. The pathological anatomy of anthrax shows no essential differ- entiation among the bovine or equine species. In cattle which have perished during or of the disease in its acute or apoplectic form, we find the blood of a black-red color, thick and tar-like, and without the ability to coagulate. The bhxjd has the same character during the intra-vital progress of the disease ; the entire venous system is congested ; the ingesta are frequently mixed with extravasated blood ; 114 THE DISEASES OF DOMESTIC ANIMALS. the intestinal parietes, especially of the jejunum, are more or less infiltrated with a sero-hsemorrhagic mass. Similar gelatino-haemor- rhagic infiltrations may be seen in the omentum, mesenterium, in the eapsula adiposa of the kidneys, the connective tissue of the in- ferior parts of the neck and mediastinum. A sero-haemorrhagic effusion is frequently to be met with in the abdominal and pleural cavities, particularly the former. Ecchymoses of variable dimensions are frequently to be met with in the muscles of the heart, also extravasations of variable extent under the endocardium and epicardium, particularly about the auri- cles. Hsemorrhagic effusions are frequently to be met with in the sexual organs of females. Genuine carbuncular eruptions are sel- dom met with along the intestinal canal of cattle. The rigor mortis is not of a very severe grade ; a frothy, blood-stained fluid is fre- quently to be seen issuing from the natural apertures of the body ; the abdomen is frequently distended with gases. If animals are slaughtered early in the disease, it is frequently impossible to con- jecture its nature, if they have been allowed to bleed freely, and the intestines, etc., have been carefully removed. This is an important fact from a public-health point of view. The chief patho-anatomic variation in horses is that we meet this gelatino-hsemorrhagic infiltration to a far greater extent than in cattle. This peculiar yellow, serous, blackish infiltration is difficult to describe ; but, after having once been seen, it does not easily pass from remembrance, and, aside from anything else, even the fre- quently asserted pathognomonic tumefaction of the spleen, is one of the most characteristic pathological phenomena of anthrax. These infiltrations may be met with wherever we have normally loose con- nective tissue, the retro-pharyngeal and laryngeal region, along the trachea and large blood-vessels and nerves, in the mediastinum and mesenterium, the organs of the pelvis, and fatty capsule of the kid- neys. The disease is not so marked along the intestinal tract in horses as in cattle ; but we find carbuncular eruptions and erosions to a greater extent than in the latter. The large glands of the body — kidneys, liver, spleen — are gen- erally tumefied, the parenchyma clouded, and the vessels filled with blood. The lymph-glands also show signs of hypertrophy, and many bacteria are to be found in them. Aside from the characteristic bacteria, we find the white or col- orless blood-cells numerically increased, sometimes immensely. Leucocytosis. — ^This condition is a transient numerical increase INFECTION. 115 of the white or colorless blood-cells in proportion to the red, while leucaemia is a permanent increase of the former over the latter. This increase is to be traced to the hyperplastic condition of the lymph-^Jauds and spleen. The red blood-cells seem to suffer some changes ; they are less tirm in their contours, and have a greater degree of adhesiveness than is conimon to them. Bacteria are, naturally, to be discovered only by the use of the microscope in the entire capillary system, many of them being vir- tually the seat of embolic bacterial obstruction. The parasites are also plentiful in all the effusions and extravasations, and frequently among the tissues. In the smaller animals the necroscopical phenomena of anthrax are far less characteristic : the spleen is but little enlarged ; the sero-hfemorrhagic infiltrations are by no means so numerous, as well as the extravasations. A special tendency to rapid cadaveric changes does not seem so common to cattle, sheep, and goats, as to horses. The rigor moi'tia often fails, or is present to a minor degree. Pi'ogjiosis. The prognosis in anthrax is to be considered as exceedingly un- favorable, sixty to seventy per cent of the cases ending fatally among the larger animals. In the acute and apoplectic forms re- covery seldom takes place, and in the sub-acute the mortality is very great. Diagnosis. The diagnosis is often very difficult intra vitajn^ especially with- out recoui-se to the microscope, in sporadic cases in localities where the previous occurrence of the disease does not give cause for sus- picion. During the intermissions of the disease, the microscopic exami- nation of the blood is often followed by negative results, as well as inoculative experiments. However, these should ever be resorted to, and, when taken in unison with the above detailed necroscopic phenomena, one need seldom make a mistake. The bacteria may, however, generally be found in the blood soon after death. It must not be forgotten that putrefaction is op- posed to the life of the bacteria. On account of the extreme degree of infectiousness possessed by this disease, the practitioner must ever remember that, in a certain sense, he takes his life in his hands in making autopsies upon ani- 116 THE DISEASES OF DOMESTIC ANIMALS. mals which have died or are suspected to have perished from it. "With wounded hands, or even the slightest abrasions of the cutis, no one should make such an autopsy. Great care must be taken not to wound one's self with the knife, or upon sharp edges of broken bones, for death is almost sure to follow. While a student in Yirchow's laboratory at Berlin, the body of a tanner who had died from anthrax was brought in ; the patient had simply removed the scab from a razor-scratch on his neck with the edge of a raw South American hide — sun-dried, however — which he was carrying. This case also illustrates the extreme tenacity of the germs of anthrax when dried. Prophylaxis. Notwithstanding the prevalence of the idea that the prevention of the enzootic or sporadic outbreak of anthrax in regions where it has constantly appeared is a task of great difficulty, we must say that this does not accord with practical experience, as we have proven by examples taken from the observations of persons of undoubted ability. Although it is beyond question that such soils or districts are highly infectious, yet we know that the thorough disinfection, and other removal of cadavers than by burying, also a similar care with reference to the excretions from such animals, have tended greatly to diminish the annual losses from the disease in notorious districts. Diseased animals, as well as their cadavers, must be thoroughly protected from the attacks of flies, by keeping the stables dark, blankets, etc. As an excess of moisture, or drying out of the ground-water, are both known, under certain previously mentioned conditions, to favor the development of the bacteria, and consequent infection of animals exposed thereto, and as practical experience has proved that thorough draining of such districts has been of beneficial effect, this procedure should always be resorted to. Animals should never be allowed to graze upon known anthrax districts or suspected pastures. Such places should be fenced off and used for agricultural purposes after careful drainage. While these remarks upon the soil as an infectious medium should by no means be disregarded, still there are numerous obser- vations and experiences on the part of unquestionably competent men which seem to stand in open contradiction to the theory of the infection of the earth by means of the cadavers of anthrax-diseased animals. INFECTION. 117 "Wliile so high an authority as Pasteur asserts that the soil takes up the bacteria and preserves them, and acts as a medium of culture for them — also claiming to have found the common earthworm im- pregnated with them, and looking upon the latter as a vehicle aid- ing in their dispersion — we know that putrefaction is opposed to their life and proliferation. All cadavers have to undergo the pro- cesses of putrefaction and chemical decomposition. Collin buried anthrax victims within a limited district, and used every means kno^vn to be favorable to the life of the bacteria, yet be fed thirty-five animals with plants in every condition grown upon such soil without producing any evil effects. Professor Feser buried a very large number of animals which had perished from inoculated anthrax, and from which repeated successful intra-vital and j^ost-morteni experiments were made, in the grounds around the government experiment station at Leng- gries, in Upper Bavaria, yet during the ensuing summer, when I was assistant with him, we were unable to produce a single success- ful inoculation, not only from the soil, but from the remnants of the cadavei*s. The same results followed like experiments made with material taken from a very large number of places where an- thrax-diseased animals had been buried in the mountains. Roloff, the present director of the Berlin school, is, however, a strong partisan for the infectiousness of such places. Therapeutics. The administration of the antiseptics has been extensively tried, and, in general, found unavailable in the treatment of this disease ; although large doses, as large as safe, of carbolic acid, are said to give favorable results to^some practitioners. Immunity. The question of the immunity to infection on the part of indi- viduals of the same species of animal life, as well as the immunity against certain diseases of other species which exist all through the animal kingdom, is one of the most hidden subjects in connection with the study of disease. The consideration of this subject belongs, rightly, in our general remarks upon bacteria ; but for special reasons we have placed it here. "W"e know that one condition to infection is expressed by the practical tliough scientifically blind remark, want of susceptibility. In what this consists we know not. Not every person exposed to 118 THE DISEASES OF DOMESTIC ANIMALS. variola acquires the disease ; the same is true even of syphilis, gonorrhoea, diphtheria, and all the contagious diseases of man. It is equally true with regard to pleuro-pneumonia, anthrax, rinderpest, etc., of our animals, though the individual immunity to infection is far less in some diseases than others. Again, syphilis can not be transmitted to our domestic animals ; the glanders to the bovine family ; pleuro-pneumonia to man, or most other animals, and so on of numerous other diseases ; while rabies is the most generally infectious of all contagious diseases, passing to nearly all warm-blooded animals. Foot-and-mouth disease is, again, very general in its ability to infect the various species. Man has a far greater receptivity to the contagious diseases of ani- mals than they have to those of man. The carnivora possess a very slight degree of receptivity to an- thrax, while birds and fowls are said not to possess any in a natu- ral condition. Pasteur has endeavored to show, and has, in fact, ap- parently experimentally proved, that it is the high temperature of fowls, 42° C, which is the cause of this immunity to anthrax infec- tion, formally the bacteria do not develop in their organisms, but, when he cooled their bodies off artificially, they did develoj), and the fowls died. I can not accept these conclusions, and think the immunity of fowls must rest upon something else than their high temperatures, for we know that a temperature of 42° C. is not at enmity with the life of bacteria. At the time that the above-mentioned experiments of Pasteur came out, I was myself busy in the experimental study of bacteria, particularly bacillus anthrax. In the disease itself in cattle, sheep, horses, and rabbits, the temperature frequently rises above 42° C. ; then why do not the bacteria cease to develop, and the animals re- cover ? I have frequently inoculated sheep that had a normal temperature of 42° C, yet the bacteria developed and the animals died. Success- ful reinoculations were also made from them. I have inoculated horses suffering from influenza and pneumonia that would surely have ultimately recovered, with a temperature of 42° C. or more, yet the animals died from anthrax, and a plentiful development of bacteria took place. The above condition is what is called "natural immunity." We have also what is known as " acquired immunity." A person who has once had the measles, whooping-cough, scar- latina, variola, etc., seldom has the disease a second time. Excep- INFECTION. 119 tions do not contradict the validity of a rule, though they would a law of nature. The same is true of pleuro-pneumonia. Another form of acquired immunity is that produced by inocula- tion, as in variola, pleuro-2)neuin()nia, and, according to Pasteur, in chicken-cholera and anthrax. By this procedure the artificial pro- duction of a mild form of the disease is able to prevent natural infection. According to Pasteur, we have a still mure striking phenomenon in anthrax. His experiments led him to affirm that the inoculation of ani- mals with a virus which has been attended by a certain series of arti- ficial cultivation, made in a peculiar manner, was capable of prevent- ing the eniption of the diseases when inoculated with blood of a most virulent character. He says : " Fifty sheep were placed at my disposition for inocu- lation. Twenty-five of them were inoculated with a known virulent nuiterial, and twenty-five were vaccinated with a prepared attenuated virus. The first twenty-five all died. Two weeks subsequent to the vaccination the other twenty-five were reinoculated witli a vims of known malignancy : they all resisted infection. (This subject is of the greatest importance, but governmental support is necessary before we can thus advance the science of preventive medicine in this country.) Again, there is a species of acquired immunity of another kind. It is known that syphilis is slowly becoming less virulent among the people of the civilized world. AVe are less open to infection, and the disease is not so malignant. People acquire a certain degree of immunity against the poisonous action of certain drugs, by gradually mcreasing the amount taken, as illustrated both by the sick-bed and by acquired habits in the use of opium, arsenic, or even those luxu- ries tobacco and alcohol. The first cigar makes us sick, but finally we can smoke all day. So it is with alcohol : we can gradually adapt ourselves to larger and larger quantities. To my mind there is but one explanation to all this, and tliat of a very philosophical (i. e., theoretical) nature, although we have observa- tions and experiences in the natural worhl whidi serve to confirm our theory. The two great forces which Darwin claims have exerted an in- fluence upon the changes that centuries have produced in the forms and characters of any species of animals, are — 1. The struggle for existence. 2. The gradual adaptation to natural conditions and surround- 120 THE DISEASES OF DOMESTIC ANIMALS. ings, by wliicli are meant food, air, water, temperature, cli- mate, etc. These two influences liave tended to fasten upon a given species certain characteristics which become transmissible or hereditary. The struggle for existence leads to the survival of the fittest. We have already said that in all life this struggle existed. It exists not only between all members of the same species, inclusive of man, but also between the cells which make up our organs. In the battle for nourishment, only those cells which are best adapted, from their chemical and physical characteristics, to their specific work, survive ; the others perish. The worn-out are continually replaced by the new. It is so in all life. By contagious or infectious diseases we have learned, to our sat- isfaction, that a living organism enters the animal body. Being a li\ang organism, it must naturally seek for the necessary constit- uents to its nourishment within the organism, or else it must die. Where it does not find it, it causes no infection ; with its inability to procure it, the disease caused by it must cease. We have learned that the life of the foreign organism is depend- ent on most of the elements of nourishment upon which the life of the animal organism, as a whole, or its individual parts, the cells, depends. The red blood-cells euter into a struggle for existence with the bacteria for that life-gas, oxygen ; the various other cells of the body for the different chemical constituents necessary to their life, the sum total of which constitutes the life of the infected or- ganism. In this struggle, one or the other must win. If the cells are the stronger, the bacteria perish, and the animal or individual infected lives. If the bacteria are stronger ; if, added to their parasitic na- ture, they also produce chemical stuffs at enmity with autositic life, they are in a measure supported by an ally in their stiniggle with the cells of the body, and the autosite dies. But, with reference to the immunity acquired, we have but one reasonable explanation, which is that, in some unknown way, the cells are enabled to withstand the influences of their parasitic ene- mies ; they gradually acquire a nature which renders them insus- ceptible to further attacks — i. e., they adapt themselves to the influ- ence exerted by the above-named poisons. Like the habitual drinker or smoker, the cells are the same as the individual of which they are the component units : they become accustomed to the alcoholic poison. So it must be in those cases where immunity follows vaccination INFECTION. 121 or inoculation. The cells become accustomed to the material in- troduced in such small quantities, or it becomes so changed that it is robbed of sufficient uf its deleterious characteristics, so that, ^vhile accustoming themselves to its action, they arc still able to overcome it in the struggle for existence. The continual infection of the human race with syphilitic germs for centuries has hardened the cells of the organism, so that they can better resist their attacks on exposure to infection. In the nat- ural world, this acquired adaptability to circumstances exerts such an inlluence as to become strongly hereditary : may it not be so, in a less degree, with regard to some diseases ? There seems to be no other reasonable hypothesis by which we can explain both the natural and acquired immunity which the animal species possess against certain forms of infectious diseases and poisons. Summed up : Either the cells are strong enough to win in this struggle for life ; or, in the struggle, they become, as it were, accus- tomed to such influences, and are no more open to the attacks of the germs ; or they are overcome in the struggle, and the autositic or infected organism dies. Anthrax in M^vn. Pustula Maligna, Carbu7icidu8 Contagiosa. The fact that this disease is transmissible to human beings should be known to every one. On account of the liability to infection of those having the care of anthrax-diseased animals, it is essential that the veterinarian, as well as the public, should have some knowledge of its deportment in the human organism. Until recent years the disease has been looked upon l)y most medical writers as belonging exclusively to the surgical branch of medicine. That the disease occurs in human beings was known to very early medical writers. I^iiologj/. The idiopathic or spontaneous eruption of the disease must be strongly contradicted, especially as we have conclusively shown that such is not the case among animals. There are no sufficient proofs that show that the disease ever occurs in man, except by direct inoculation from diseased animals, or their products. ^ledical writings do not give any evidence that the disease ever occurs among human beings from the mere residence in notorious anthrax districts. 122 THE DISEASES OF DOMESTIC AXIMALS. Man acquires the disease — 1. By direct inoculation. That is, persons acquire the disease whose occupations bring them in direct relation either with anthrax- diseased animals or their products. The most dangerous procedures are phlebotomy, slaughtering, and skinning diseased animals. The infection is in general external, and we can generally find some wound or excoriation which made the atrium to infection. 2. By the consumption of the flesh of diseased animals. Exco- riations or wounds along the whole extent of the digestive tract may be atria of the disease. This form of infection is veiy rare, but a sufficient number of well-constituted cases have been recorded, many of them termi- nating fatally, to make the consumption of such flesh a forbidden article of food. 3. By means of flies and insects. Cases of this kind of infection have been far more numerous than the former. 4. Infection from man to man has been observed, but few cases have been recorded, however. Those parts of the body upon which infection has primarily taken place are generally the uncovered (84 per cent, Yirchow), such as the face, lower arm, hands and fingers, and neck ; or, in other words, infection takes place most frequently in those parts naturally exposed to contact with infected material. Summed up, we may say : Anthrax occurs most frequently in man in those places where it prevails to the greatest extent among animals, and among those whose manner of life brings them more or less intimately into relation with the diseased animals or their products — such as those employed at tanneries, wool-pulling estab- lishments, and horse-hair factories. The susceptibility to infection is less in man than in the larger domestic animals. Man enjoys no immunity to secondary infection from having once had the disease. (This seems to stand in more or less direct contradiction to the experimental results obtained by Pasteur and others.) Symptoms and Course. We will not go into detail, but shall simply consider the chief primary symptoms, such as we should observe in a groom, or a per- son in whom infection would be likely to take place, for the treat- ment of the disease is such that an accomplished veterinarian might INFECTION. 123 sometimes be the means of saving eitlier his own life or that of others by immediate action, in cases where the dehiy in procuring a doctor wuukl be frauglit with great danger to the infected pei*son. The period of incubation is seldom less than from four to seven davs (thouirli sliorter periods have been affirmed), and never longer than from twelve to fourteen days. The lirst indications of infec- tion are sensations of burning and itching, similar to the sting of an insect, upon the ]>arts where infection took place. Such places ap- 2:)car as small, reddish tlea-bite sjmts, with a blackish center. The spot at first swells, but rapidly becomes an itching nodule, upon the apex of which appears a reddi.sh or bluish vesicle, which soon bursts and presents a dark-red base. The patient frequently de- stroys these vesicles by scratching before they come to maturity. The excoriated places become dry, brownish, or red, and scab over ; a red or violet circle surrounds them, upon which small vesicles soon develop. These secondary vesicles contain a yellowish, red- dish, or blackish fluid. The circle sometimes fails, but in general extends, becomes more and more tumefied, and the surroundings oedematous and verj' extensive. It is not necessary to our purpose to extend these remarks fur- ther, but the detailed account of the symptoms of anthrax can be studied in any good work on human medicine. The disease generally runs its course in fatal cases in from five to eight days. The first phenomena of the disease after the consumption of the flesh of diseased animals generally appear very rpiickly : in six to eight hours. The patients complain of shivering, weakness, headache, or general sickness. Death frequently results in two or three days. Peculiar pustulous or carbunculous centers are frequently to be met with in the digestive tracts ; transudations in the cavities of the body, sero-hfemorrhagic infiltrations of the loose connective tissues, glands, etc., in which as well as the carbuncles the characteristic bacteria may be found, as well as in all the capillaries of the body. Beautiful microscopic specimens showing the bacteria may be prepared from the skin, kidneys, or other organs. The diagnosis is comparatively ea-sy where reasons for infection exist. The examination of the blood with the microscope should never be neglected, particularly of blood o])t.'\ined from suspicious wounds or i>ustules, as the bacteria remain much longer locally con- fined than in animals. 124: THE DISEASES OF DOMESTIC ANIMALS. Therapeutics. The chief aim is prevention of infection, much of which depends iijDon the veterinarian instructing those exposed to the danger of infection as to the care of their persons and of animals that may- have the disease. The danger which may arise from the bites of flies, and the necessity of keeping cadavers covered, and of care in han- dling them, should ever be especially emphasized. The chief therapeutic interference consists in the thorough de- struction of the local centers where infection has taken place with concentrated carbolic acid, or nitric or sulphuric acid. If the car- buncle is fully developed, it should be at once cut out and the wound thoroughly cauterized. In inward infection by means of the digestive tract, appropriate doses of carbolic acid and quinine should be resorted to in unison with iron, wine, and other tonics. Anthkacoid Diseases. This name has been given to a group of diseases in which the necroscopic phenomena are more or less allied to those of anthrax. They are unquestionably germ or infectious diseases, but differ from anthrax in wanting the specific bacteria of that disease in their course, and the clinical or intra-vital phenomena. These facts should ever be borne in mind in the nomenclature or classification of diseases. In veterinary medicine we have never yet arrived at an indi- vidual independence, and our pathological anatomy is far more human than zootomic. But, what is still more absurd, clinicians, and especially the authors of our books, both past and present, have given names to diseases of our animals because of some fancied re- lation in the clinical phenomena to human diseases. They have forgotten that the caiise of a disease should ever have much to do with its nomenclature or classification. What real relation have the diseases called measles or scarlatina of our animals to the diseases of that name in man ? Not only are they pathologically different, but their cause is different. The measles of the hog is the cystic form of an animal parasite. It is an invasive not an infectious disease. To speak of scarlatina, or typhus, of the horse or any animal is equally absurd. There are peculiar infectious diseases of man due to specific causes which have never yet been known to exert any in- fluence on animals. You might fill a stable with horses and with INFECTION. 125 cliildren having scarlet fever, but no infection would take place ; or strew its floor with the alvine dejections of typhus patients, with- out causing infection of the horses. Who ever saw the characteristic lesions of the Fever's patches of human abdominal typhus in the horse or any animal i The diseases which we will consider imder the head of anthra- coid are the so-called emphysema infectiosum (black quarter) of cat- tle, splenic or Texas fever, and the hog-cholera. The disease which Eoell calls typhus equina (purpura of Will- iams), and which he looks upon as anthrax or nearly akin to it, bears far more relation in its clinical phenomena to anthrax in man than to genuine anthrax in the horse, though it is uncjucstionably an infectious disease and not a consequential complication of the infectious pneumo-enteritis — influenza — of the horse, or strangles, as some veterinarians claim. It occurs as frequently idiopathically as it follows either of these diseases. In such cases they simply act as a purveyor or preparer of the equine organism to the action of a new inficieus. EMPnYSEMA Infectiosum. This disease, which is known to lis as black quarter, from the peculiar color of sections of the muscles, or as Rauschbrand to the Germans, from the peculiar rustling which follows stroking the skin or cutting through the flesh of such animals, has quite a number of pathological phenomena in common with anthrax, and frequently occurs in the same localities. In its clinical appearances it is very diflerent. It is peculiarly a bovine disease ; but I have had a case in a horse in Boston during the past year. I saw numerous cases of the disease among cattle during my studies of anthrax in the Bavarian mountains in 1878. In the following remarks I shall mainly follow the description of the disease as given by Professor Feser, who with Bollinger has been the only one that has given any special study to it. This disease of cattle has undoubtedly been known for a long time, but has always been looked upon as an abortive form or pecul- iar symptom of anthrax, no independent study of it having ever taken place until the two observers named paid especial attention to it. It occurs everywhere, but the Bavarian Alps are especially visited by it. It is not so much found in the hot months as anthrax, but in general occurs at about the same period. It is neither anthrax nor any form of anthrax. 126 THE DISEASES OF DOMESTIC ANIMALS. Etiology. Like anthrax, it is also due to specific infectious elements belong- ing to the same class of bacteria — the fission fungi. The bacteria of this disease are shorter and finer than those of anthrax, and do not end with the abruptness which is the characteristic of bacillus anthracis. They are also movable bacteria, while those of anthrax do not in general betray any motion. They multiply by spores. Feser gives the following necroscopical description : " Distinct rigor mortis of the well-fattened cadaver. Visible mucosee dark red. The left over-arm, the left shoulder and a j^art of the right, and the middle portion of both posterior limbs were much tumefied, and a distinct crepitation — rastling — was both to be felt and heard on passing the hand heavily over these parts. The axillary and inguinal lymph-glands were to be distinctly felt as hard nodes un- der the skin. The subcutis and tendinous aponeuroses were filled with a yellow, gelatinous infiltration in those places which were tumefied. The connective tissue in the vicinity of the large vessels was much thickened and infiltrated with a mass similar in appearance to the above. The muscles appeared in many places of a dark-red color — red infiltration — rich in blood, softened, emphysematous, crepitating, and of a peculiar sweetish, sickly odor. (This odor of the flesh in this disease is very striking, but can not be well de- scribed.) The blood which oozed out of the vessels was black, viscid, and tar-like. "The above-mentioned lymph-glands were swollen, soft, and full of blood. " The abdominal cavity contained a reddish-black, peculiar-smell- ing exudation. Peritoneum clean, lustrous, and smooth. In the vi- cinity of the kidneys was a tumefaction filled with a yellow, gelatino- haemorrhagic infiltration. Omentum infiltrated here and there as above. The contents of the rumen soft, the epithelium, or rather the mucous membrane, frequently peeling off and attached to the ingesta. Reticulum filled with soft ingesta ; epithelium intact, without injection of the vessels. Contents of the omasum firm. Abomasum filled with a reddish-brown fluid, the contents having a fetid odor ; epithelium adherent ; mucosa swollen, dotted with ecchymoses and hsemorrhagic infiltrations, or rather diffuse ligemor- rhagic centers. At the beginning of the ileum was to be seen a very much contracted portion one decimetre long, of a diffuse dark- red color ; the walls were thickened ; the epithelium desquamated, and the underlying sinuses exposed. This portion of the intestine INFECTION. 127 was filled with a blackish couguluia. Many other portions of the intestine were the seat of diffuse red intiltration and eechynioses. The epithelium was loose and easily detached ; the contents of the intestines in tjjeneral of a yellowish-red colur, creamy, and full of ^a&- globules. ^«othing particular to be remarked in the large intestines. Kectum stained dark red in luuny places ; fieccs wateiy and green in color. "The spleen was enlarged from two to two and a half times its normal size ; of a dark-brown color outwardly ; inwardly almost black, soft, and disorganized. Liver dark red in color, swollen, and full of blood. The blood was coagulated in the large hepatic ves- sels ; kidneys, bladder, and testicles offered nothing very abnormal. "The thoracic cavity contained a small amount of a sero-ha*mor- rhagic exudation. The left costal pleura presented ingested vessels, circumscribed red infiltrations and ecchymoses. Both lungs filled with blood, but contained air in all parts ; here and there dark-red spots. The pericardial sac contained a small amount of clear serum (the normal quantity is somewhat less than a tablespoonful, about ten grammes); the muscles of the heart of a dark-red color, with here and there dark striations. The ventricles contained a con- siderable quantity of a dark, black-red fluid and some coagulum ; yellow sero-h{emorrhagic infiltrations into retro-pharyngeal and laryn- geal spaces. " Microscopic examination : " a. The blood from the heart contained, aside from the blood- cells, numerous micrococci and long, straight, and delicate movable bacteria, from 0*005 to O'Ol millimetre in length. "J. The spleen contained the same parasitic objects in addition to its usual elements ; also the ingesta. "r. These bacteria were also numerously represented in the eero-hajmorrhagic infiltrations and the dark stained j)arts of the muscles."' Feser gives the following resume with reference to his observa- tions and experiments : The disease known as llauschbrand presents similar phenomena wherever it appears. The animals look as if the cutis had been blown up, and crepitation may be heard and felt on parsing the hand over any such parts. The gas from these emphysematous tumefactions burns with a pale-greenish color. The disease is confined to localities, and appears with varying constancy each year, causing with anthi-ax the chief losses of herds- men. The disease appears especially in the summer and fall months. 128 THE DISEASES OF DOMESTIC AXIMALS. Young animals are far more susceptible to it than old ones. In the latter it is a very rare occurrence. The microscopic examination of the blood, iiesh, etc., of the dis- eased animals allows us a Yiew of the nature of the disease, for everywhere we find the same characteristic — movable, delicate bacilli and micrococci. The disease, in all probability, must be looked uj^on as an acute putrid infection. Numerous facts seem to strengthen this view. Aside from the resemblance of the bacteria to those frequently found in putrid masses, we have the acute course, the complication of the lymph-glands and spleen, the textural decomposition, the de- velopment of gases, and its transmission to other animals by injec- tion of its fluids into their organisms. The necroscopical results following experiments with purely septic fluids are the same in general as those obtained in this dis- ease. The fact that similar bacteria are to be found in the surround- ings of the animals — swamps, stable-fluids — makes it almost sure that this is due to infection from outward and the multiplication of the germs in the infected organism. The disease is neither contagious nor is it of a transportable nature, and thus is strongly distinguished from true animal pests. Infection from animal to animal, or by means of vehicles, has never been proved. The diseased animals come as isolated cases in the midst of numerous others, both in the fields and stables. Some- times several cases may occur among a herd ; but then they have been exposed to the same external causes, and of the herd are those in which the inner condition renders them susceptible to infection. This predisposition to the disease must be especially emphasized, otherwise we are utterly unable to explain why it should only oc- cur in young animals, and of these the best developed and con- ditioned are in general the ones to become affected, while the re- mainder of the herd are subjected to the same feed, and exposed to like external conditions. The flesh from such animals has and re- tains an alkaline reaction, while normal flesh soon acquires an acid reaction. The therapeutic treatment of animals ha^nng this disease has so far been entirely useless. Carbolic acid, and external cleansing and disinfection of the animals, should be tried, however. Experience has proved that the meat from such animals ca7i be eaten, if well cooked, with but little danger to the consumer ; whether it is justifiable or not, is another question. If it is to be so INFECTION. 129 used, the animals should be killed when first attacked, and the flesh cooked and eaten as soon as possible, as the meat soon suffers putre- faction. Bollinger gives the following conclusions with reference to his study of the disease : 1. The disease is neither a form of anthrax nor of septic or pu- trid infectitin, but — 2. It may be considered as a mycosis of a most dangerous kind, which invariably terminates fatally. 3. The infectious elements may be either endogenous or ectoge- nous. 4. The disease, like anthrax, belongs to those forms which may be transmitted by the soil. It is not contagious. 5. The infectious elements are active when introduced into the subcutaneous tissues, but also when introduced into the digestive tract. 6. The disease can be experimentally transmitted to cattle, sheep, goats, rats, and mice, though cattle become only infected in a natu- ural way upon enzootic outbreaks. 7. Bollinger gave it the name of " emphysema infectiosum." ^Ve have now come to the consideration of a disease of the bo- vine family which seems to be essentially American in its nation- ality, the — Texas, Spanish, or Splenic Fever. I wish it were possible for me to refer to a really reliable report or description of this disease. My own studies have been made upon the report of John Gamgee to the Commissioner of Agricult- ure of the United States, on animal diseases, and published in 1871. I wish it were possible for me to say one single word in favor of this report. It is a disgrace to the veterinary profession, to the man who wrote it, and to the Government which published it. It is a miserably arranged, illogical, and erroneous production. Symptoms, definition, and periods, are mixed up, and there is no connection between the parts. The pathological anatomy is simply abomina- ble, and one which I should be ashamed to have a student produce. * Ilistonj. An attempt at the histr^ry of the disease is made by another than Gamgee, but is of such a quality that we do not need to refer to it. 130 THE DISEASES OF DOMESTIC ANIMALS. Definition or Nature of the Disease. Gamgee says, " It is a disease peculiar to the bovine species, •which has never been described as attacking Southern cattle, and which occurs in a more or less latent form among them." I admit my inability to comprehend the above language. Even though a disease appears among a certain species of animals in a " latent " form, it still attacks them, and we know that it does attack the cattle of Texas, or it would not have received its name of Texas fever. Texas fever should be described as a peculiar infectious disease of cattle, due to some unknown inficieus, undoubtedly of a bacterial nature, which for its primary generation is dependent upon special localities, climatic and telluric conditions. With reference to its " latent " or mild character among the cattle native to the localities where it originates, it exactly cor- responds to the rinderpest of Europe, which appears in just such a form among the cattle which graze upon the places where it is said to originate, viz., the vast steppes of Kussia. It also bears some resemblance to this disease in its clinical phenomena, as well as pathological, but differs from it in not being strictly contagious, that is, passing from animal to animal. I have been unable to find anything in this report regarding the influence of the infected localities upon new stock imported from other places to them. It is like anthrax or black-quarter in that it is confined to locality, and some pathological phenomena, viz., the enlarged spleen. Gamgee says further : " It is, so far as we have ascertained, in- capable of communication by simple contact of sick with healthy animals ; and, in the strictest sense of the terms, is neither contagious nor infectious P That it is not contagious, there seems to be unquestionable evi- dence, for we read that when Texan cattle are put in a pasture, and merely separated by a fence from other cattle native to these places, that the latter do not acquire the disease. But that it is not an in- fectious disease is quite another question. That it is not an infectious disease as a contagious disease is, we freely admit ; but that it is an infectious disease of a very malig- nant type we positively assert. In this regard it is very interesting to note that it exactly cor- responds with an infectious disease of man, which is bound on nearly the same localities — viz., yellow fever. INFECTION. 131 While the nature of this disease is still a matter of grave discus- sion, all authors unite in looking upon it as malignantly infectious, still the greater majority deny that it is also a contagious disease. Like Texas fever, the yellow fever is confined to localities, upon moist regions, and a hot climate for its generation. By south and west winds its ravages extend, while the cooler winds of the north and east seem to check them ; and in a northern climate it does not prevail, or dies out of itself. The same is the case with regard to Texas fever : the famous " northers" of the Texas plains having the influence of checking or putting an end to its ravages, and it dies a natural death in a northern climate. The yellow fever, again, takes a milder or latent form among people indigenous, acclimatized to the climate and telluric influence, as does Texas fever among cattle ; some races, as the negro, are said to be almost exempt from its ravages. Is^aturalized persons, once having had the yellow fever, acquire a certain degree of immunity from a second attack, which they lose, however, if they leave such regions for a time and then return to them. Our ''report" does not tell us Avhether Texan or naturalized cattle acquire such an immunity from second attacks of the Texas pest. Provided susceptibility to infection exists, the inficieus of yellow fever enters the human organism and causes the disease. They are said not to reproduce themselves (?) in the infected organ- ism, but to act directly ; they do not pass from one organism to another — contagion. They retain, however, their infecting power a long time, when once infesting a vehicle, and are highly transportable, either by means of the sick, or ships, etc. Our National Board of Health has given a great deal of attention to this disease, and reports that it is a locally-generated infection, and looks upon the inficieus as some at present unknown form of bacterial life, which it hopes yet to discover, and then to be able to prevent its action. Tiiis Texas fever exactly corresponds to the above, and it is no less the duty of our Government to spend time and money in search- ing for its cause, than it is to study the same with regard to yellow fever. Gamgee says the disease " is not infectious^ in the strictest sense of the term.'''' We assert the contrary, and will quote his own testi- mony in proof of our assertion, and to show the utter fallacy of his words, which will sufficiently indicate the weakness of his report. On 132 THE DISEASES OF DOMESTIC ANIMALS. page 87 lie says : " Nevertheless, there are important data which in- dicate that, from the period of arrival of a Texan herd on any distant or any defined pasture, jive to six weeks elapse 'before the disease ajp- jpears in the indigenous stock, grazing icith or after Southern cattle. It is proved that animals may simply pass leisurely over a road or prairie, feeding as they move along, and, without remaining for any length of time on any portion of the ground they traverse, leave he- }iind them a poison suffi^cient to destroy all, or nearly all, the cattle which continue to feed ujpon itP He then goes on to give cases illustrating this statement. On page 88, he says : " At Tolono the largest body of Texan cattle arrived toward the end of May, and the disease broke out (in the native stock) on the 27th of July. One gentleman of Tolono gave accommodations one night to three hundred Texan steers, on the 25th of June, and the disease appeared among his own stock on the 28th of July. In Champaign County, Texan cattle were placed on the prairie on the 15th of June, and the indigenous stock hegan to die on the 3d of August, twenty out of thirty-eight head dying in four days." " Thus we see that thirty to forty days elapse between the plac- ing of Texan stock on a pasture, and the manifestation of the dis- ease to the stock-owners of the neighborhood ^ If this is not being " infectious " in the extremest sense of the term, and to the full letter of the law, then I admit my utter igno- rance of the philosophical -use of language, and logical connection between cause and effect. Still further, page 109, Gamgee says : " Near Homer, where there were 4,527 Texan steers, which had been driven to Broad- lands, and had communicated disease not only to cattle feeding on their trail, but also to a herd of Illinois cattle with which they mixed in reaching their destination.'''' Page 110 : " That they " (the Texan cattle) " communicated the disease to a very serious extent is beyond all doubt. ... At the time of my visit the mortality (among native cattle infected by Texans) was raging at its highest point, and men were busy from sunrise to sunset, skinning, digging graves, and burying." The whole report is replete with such testimony. Further com- ment on our part is unnecessary. If Professor John Gamgee does not consider the disease infec- tious, the people of many of our "Western States seem to have come to quite the contrary opinion, for, in the renowned Scotchman's own words, page 121, " stringent laws have failed to avert the most dis- IXFECTIOX. 133 astroiis and wide-spread losses, and while, on tlie one hand, persons interested in the Texan trade have justitied their inattention to legal restrictions by declaring them one and all unconstitutional, instances have not been wanting of mob-law adoj^ting its own expedients. Dealers and farniei's who owned Southern (Texan) cattle have been threatened ; they have been pounced on in the dead of night, that they might surely be found in their homes, and there and then they have been requested to attend meetings of indignant and im- poverished neighbors." What more can I say ? Surely mankind never makes restrictive laws, especially in this country, to prevent tratiic in a harmless dis- ease, nor do men go about tearing people from their beds on account of a " strictly non-infectious disease." Etiology. The cause of Texas fever has yet to be discovered. Gamgee says, " It is an enzootic disorder '' (another contradiction, for enzootic itself implies some general cause, of an infectious or invasive na- ture), " due to the food upon which Southern cattle subsist, whereby their systems become charged with deleterious principles, that are afterward dispereed by the excreta of apparently healthy as well as obviously sick animals." This is a very nice way of using many words to say nothing. Modern infection knows nothing of any such "deleterious princi- ples" which work in this way. "Deleterious principles" means nothing. They might be chemical in their nature, which would be utterly incompatible with all our present ideas of infection. They might be gases, although modern observer do not accept gases as infecting material ; gases they should be, to conform with the gassy nature of the report. Stages of the Disease. Gamgee speaks of four stjiges or periods of the disease, and yet he says it is not an infectious disease. Pathology teaches that only infectious or contagious diseases deport themselves in this manner. lie speaks of — 1. The incubative stage. 2. The invasive stage (an infectious is not an invasive disease, this term being used with reference to the action of animal parasites ; hence we should say the period of active infection). 3. The congestive or bleeding stage. 4. Termination. 134 THE DISEASES OF DOMESTIC AXIMALS. I would classify the disease as follows : 1. Stadium ineubationis. 2. Stadium accrementi. 3. Stadium decrementi. 4. Stadium lethalis ; although I do not see the necessity of a f oui-th stage, as it is always but the final determination of the disease. 1. Stadium incubationis. The period of exact latency or incuba- tion has not been accurately determined ; it is not so well marked as in many other infectious diseases, but may be said to be from thirty to forty days. 2. Stadium accrementi. The period of active infection — i.e., the progressive stage of the disease — is first indicated by a rise in tem- perature. The temperature varies from 102° to 107"8° Fahr. This period extends to from four to seven days, and should also include the haemorrhagic stage of Gamgee, which, according to him, lasts from two to six days longer. 3. The stadium decrementi is of indefinite length, but begins with the cessation of the progressive or active symptoms. Intravital Phenomena. The ears of the animal droop, its movements become sluggish, and the secretions retarded, especially in milch-cows. The appetite at first continues as well as rumination ; a disposition to lie down soon makes itself apparent, and, wherever pools exist, the sick ani- mals apparently seek them out to lie in. Some observers assert that a cough appears early in the disease, but this does not accord with Mr. Gamgee's experience. Depression of the head, drooping ears, arched back, hollow flanks, with a tend- ency to draw the hind-legs under the body, and knuckling over in the hind fetlocks, are early and very marked phenomena. The skin appears dry and attached ; the faeces are not materially affected, but in some cases clots of blood are attached to them. The urine is at first clear. Many cases do not attract notice until the animals are sufifering from hiematuria, but the urine retains its natural color in some ten to fifteen per cent of the cases. The visible mucosae are somewhat anaemic, but a hyperaemic condition may sometimes be observed, accompanied with a viscid discharge ; the mucosa of the rectum is frequently congested. The pulse is frequent ; in the early stages hard and thin ; it gradually becomes more feeble, and in the later stages, as death ap- proaches, it is impossible to feel it. It varies from sixty to one hun- dred and twenty beats in frequency. INFECTION. 135 The therinoineter is an invaluable aid in the diagnosis of this disease. The temperature is high at the comniencetnent, but be- comes reduced with the approach of death and hivmaturia. The temperature of the external parts of the body varies. Fre(piently the poll, ears, and extremities are very hot in the active stage of the disease. At other times they are cold, particularly the posterior ex- tremities. The respirations frequently rise as high as one hundred per min- ute ; but in the comatose condition they are slow, deep, and labored. The nervous phenomena are very marked. Trembling of the muscles of the posterior parts is very frequent, as well as of the neck. "Weakness of the limbs, particularly the posterior, is very common, so that many animals are unable to rise, or, if they get up, walk with a feeble and tottering gait. Listlessness and stupor indicate the approach of the end. The state of the secretions is usually indicatory of the course of the disease. Pei-spiration is much restricted; oedema of the cutis is quite frequently met with. The urine naturally contains albumen in large quantities when haematuria is present. The milk secretion is almost if not entirely suspended. Termination. — In most cases the depression increases; the pulse becomes more feeble and accelerated, the respiration labored, and the temperature falls to 100° or 98° Fahr., and the patient becomes outstretched upon the ground and dies without a struggle. In rare cases the febrile symptoms subside, the secretions again become active, the urine clearer, and the patient recovers in a few weeks. Gamgee has seen animals apparently recovering, and again the febrile symptoms with diarrluea have appeared, and they have died within thirty-six to forty-eight hours. Po8t-Mortcd Phenomena. " That form of splenic fever wliich is most latent and seen among Southern cattle is not recognizable after death l)y tlie condition of the skin, muscles, or in many cases even by the nmcosn?, with the exception of that of the stomach." The spleens and livers are enlarged to a more or less degree. On removal of the skin, hncmorrhagcs and serous infiltrations are sometimes found beneath the lower jaw and neck. The muscular system is normal (?). 136 THE DISEASES OF DOMESTIC ANIMALS. The organs of respiration are in many cases healthy. The mouth, pharynx, and oesophagus are always healthy. The rumen is generally found full of food and its coats healthy. The reticulum has often been found the seat of red imbibi- tions. The omasum is almost invariably in a healthy condition. The abomasum, on the contrary, is almost always the seat of dis- tinct and pathognomonic changes. It is often found of a pink or dark-red color. The pyloric end is more commonly of a natural color. Minute ecchymoses are frequently to be seen studding its surface. Erosions of the epithelium are common. The duodenum is often of a deep-red color ; sometimes its mucosa is deeply tinged with bile ; ecchymoses are frequently met with. The jejunum is frequently reddened, and circumscribed haemor- rhagic centres are often to be seen. The caecum is often the seat of extensive ecchymoses ; in the colon the same. The rectum is often the seat of extensive hcemorrhages ; the liver of fatty degeneration, congested, and heavy. (I will here state the gall-ducts are filled with gall, and that the microscopic examination of the liver often reveals a most beautiful condition of natural injection of the gall-capillaries, though no micro- scopical examination of tissues or organs seems to have been made in this report.) Tlie gall-bladder is usually found distended and filled with a viscid fluid. The spleen is uniformly enlarged, and weighs from two to ten pounds. Its pulp is soft and degenerated, and oozes over the cut sm'face. The kidneys are perfectly healthy (?), but are most com- monly of a dark brown-red color from intense congestion. In the majority of cases the bladder is found filled with bloody urine. 'No marked changes are found in the nervous system, except in those cases where paresis exists, when haemorrhages may be seen in the cord of the lumbar region of varying extent. The dura and pia are sometimes the seat of ecchymoses of variable extent. Microscopic lamination. As we have said, no microscopical examination of the tissues or organs appears to have been made. Neither germs nor anything abnormal seems to have been found in the blood ; but I am entirely dissatisfied with this part of the report. Treatment appears to be useless, yet quinine in large doses and THE DOG. 137 carbolic acid in appropriate doses should be tried in case of valuable cattle, and purgatives are certainly indicated in certain conditions of the disease. Pro2)hijlaxis. In reference to Texas, or wherever this disease originally ap- peared, we are as yet in such ignorance of its true cause that we can not well speak of successful means of prevention. It wouM seem that the same rules which are applicable to an- thrax and kinilred diseases — as to draining the land, etc. — should be of value here. The trade in Texas cattle should be regulated by national laws, so that no contact between thcni and natives could possibly take place. The disinfection of rail-cai's, stock-yards, the proper isolation of pastures on which such cattle had been grazed or unloaded for a period of at least two months from the time the last Te.xans were upon them — all these measures are indicated by the report which we have just considered ; and, lastly, our present knowledge is as yet so imperfect with regard to this disease, and the losses the coun- try yearly incurs from it so extensive, it is surely indicated that our Government should institute further researches in rejrard to it. THE DOG. "We have previously considered some of the most direful influ- ences exerted by certain diseases of swine and cattle, or their prod- ucts, upon the human race, and have now to consider some of the dangers to which we are subjected by that faithful companion of man, not to be less highly prized but more carefully watched — the (log. It is very doubtful if mankind truly appreciate these dangers, threatening not only their health but their lives in too many in- stances ; and especially is this true of the dog. One of the most disturbing forms of parasitic invasion is derived in some unknown wav from the dojj. I'cBuia echinococcus is the name which has been given to the smallest tape-worm yet found infesting animal life, being about four millimetres long, and consisting of but three sections or proglottids. The scolex, or head, is marked by a prominent rostellum, or crown, and anned with from thirty to fifty liooks, placed in two rows around 138 THE DISEASES OF DOMESTIC ANIMALS. the base of the rostellum. This parasite, in its mature form, makes its home in the superior (anterior) part of the intestinal canal of the dog, where it is sometimes met with in such numbers that one could hardly believe the mass before him was made up of countless examples of this toenia. They frequently give rise to most severe disturbance to the canine organism, the animal demonstrating such furious phenomena that they have been mistaken for those of rabies. This taenia, or rather its cysticerc (embryo) form, gains access to the human organism, as well as that of many animals, as the horse, cattle, sheep, and swine, and gives rise to the development of enor- mous cysts or sacs, sometimes multilocular or compound, seriously disturbing the invaded organ. Examples of invasion among human beings have been met with among the inhabitants of nearly all countries, but most notably among those of Iceland, where, according to Thorstensen, every seventh inhabitant serves as an autosite (host) for these pests. These cysts have been found in nearly all organs. Bollinger gives the following percentage of invasions among the different or- gans of the human body, taken from 252 cases : In the liver 176 times. " " kidneys 3 " " " spleen 2 " " " abdominal cavity 54 " " " lungs 7 " " " head 4 " " " mammae (breasts) 1 " " other places 8 " Of 9,703 autopsies, made at different pathological institutes, echinococcus cysts were found as follows : * Berlin from 4,770 autopsies, 33 cases. Dresden " 1,939 " 7 " Gottingen " 639 » 2 " Erlangen " 1,755 " 2 " Zurich " 400 " 0 " Rouen " 200 » 6 " Total 9,703 " 51 " ^Naturally, the great aim with reference to this parasite, as of all others, is preveyition. This consists entirely in keeping dogs in their proper places — in absolutely disdaining all those disgusting famil- iarities which are only too frequently indulged in by lovers of ca- * Bollinger, " Zeitschrif t f iir Thiermedicin," vol. iii, p. 44. THE DOG, 139 nine pets, such as sharing bits of cake, bread, or other articles of food, drinking from a common glass, allowing them to lap one's face, or those of children. Babies of the Dog. It would be fortunate indeed for the human race were this para- sitic disease the only one to which they were liable from their canine friends. Of all the diseases, however, to which our poor humanity is lia- ble, there is not one which so calls upon our deepest sympathies as that derived from the bite of a rabid dog, known as lyssa, rabies, hydrophobia. (This last name should be dropped, as it is based upon the misleading and erroneous opinion ihat I'obid dogs are afraid of and shun water. Numerous observations have been, how- ever, recorded, by competent observers, of rabid dogs cj'ossing streams of water, and attacking animals upon an ojyposite shore.) The disease in man has been known since the early days of the Christian era. It does not seem to have been known to Aristotle, for he says : '' Dogs are subject to rabies ; it makes them mad ; all animals that they bite also become mad, with the exception of man." The validity of this last passage has been questioned. The disease in man can be said to have been unknown, at least unde- scribed, before Aristotle. It is doubtful if Hippocrates described it in the dog. Up to the time of Celsus, a. d. 2^0, we still find no description of it : it is in his writings that we iind the word " h}'- drophobia " first appearing. The views of the writers of the third and fourth centuries (Plutarch, Pliny, C.nelius Aurelius, and others) were adhered to, and but little enlarged ui^on, by medical authoi*s as late as the sixteenth century. As nearly every one knows, and as every one should know, rabies of man is a disease which oices its genesis solely to the bite of a rabid animal, more especially the dog, and is a?i acute infectious disease, having an invariably fatal termination. Tlie disease in man has been artificially communicated to animals by inoculation, but trans- mission from man to man has never yet unquestionably taken place. As said, mankind in general owes its infection to being bitten by a rabid dog : it has been statistically estimated that 90 per cent of the cases of human rabies are due to this source, while from other animals it has been estimated that 4 per cent have been due to bites from rabid cats, 4 per cent from wolves, and 2 per cent from foxes. " Of 796 human beings that died from rabies in France, "Wiir- temberg, and Milan, 710 owed their infection to the bite of rabid 140 THE DISEASES OF DOMESTIC ANIMALS. dogs, 30 to that from cats, 31 of wolves, 10 of foxes, and 1 to that from a cow." As regards that part of the human organism which has been most frequently bitten, Bollinger further says that, in 495 cases, 263 = 53 per cent, were bitten upon the superior extremities, hands and arms ; 110 = 22 per cent, upon the head and face ; and 14 = 3 per cent, upon the lower extremities. The bites upon the face appear to be accompanied with a greater percentage of mortality than those of other parts of the human body. An interesting yet horrifying example of the devastations and suffering which may be caused by a single rabid dog is given by the German veterinarians Oemler and Guenther : " In December, 1871, the dog of a butcher showed indications of being rabid. It was confined in a stable, where it tore in pieces a goat and two geese, and finally freed itself by gnawing through the stable-door. Before morning, it had bitten several dogs in the village, and then commenced roaming over the country, passing through villages, and in thirty hours encompassed some thirteen German or fifty-two English miles before it was shot. On its way it bit many living things. The people of the villages became terri- bly frightened, from the fearful tendency to bite shown by the in- furiated beast. Nine persons coming out of a church were sprung upon and terribly bitten, one of them, a woman, to such a degree as to necessitate conveying her home in a wagon. In all, fifteen persons were bitten by this dog, mostly upon the head and face ; of these eleven died of rabies." (Bollinger, loc. cit., p. 574.) It is highly probable that dogs can communicate this disease in the earliest stages of its incubation, even before any very striking phenomena of illness may betray themselves. This seems amply sufficient to explain those cases of rabies in man which have followed the bites of dogs in which no suspicious phenomena had been ob- served, and which has led to the erroneous opinion that, if a dog afterward '^ goes mad," the person bitten by it will also " follow suit," and which has also led to the serious mistake of the immediate killing of the dog. In this regard I once knew of a singular case of superstition. A coachman in one of our leading families of Bos- ton kept quite a number of bull-terriers, and indulged in fighting them: he was engaged one day in the so-called "training" of one of them, when the dog accidentally bit the man's hand. Like most of this class of persons, the man was strongly superstitious with ref- erence to the bite from a dosr : he had heard that a sure means to prevent himself from ever becoming mad was to cut the heart out THE DOG. 141 of the living dog and bind it, split open, upon the bitten part. The dog was muzzled, triced up, and the heart cut out and applied as described. As the man had not become " mad " at last accounts, he probably thinks that his " cure " was effectual. A few cases have been recorded of persons becoming infected from non-suspected but already infected dogs licking parts of their persons which were wounded, or where veterinarians have been made victims of their devotions to their studies, at a time when they had abrasions upon their hands, by making autopsies of dogs dying of rabies. About 50 per cent of the persons bitten by rabid dogs die from this horrible disease. Of 855 cases, 399 died. If we take, however, the bites which have resulted from suspected animals, and add them to the above, the percentage is reduced to about 8 per cent. Of 1,3G2 bitten by rabid and suspected dogs, 105 died. The importance of the value of cauterization of wounds caused by the bite of a suspected or rabid dog is well shown by statistics given by Bollinger, page 618 : "Of 105 deaths from rabies in France between 1850-02, 111 were not cauterized at all, 45 too late, and 39 insufficiently. Of 200 human beings bitten by rabid dogs, 134 were thoi'oughly cau- terized ; of these 92, 69 per cent, remained healthy, and 42, 31 per cent, died from rabies. By non-cauterization of the wounds in 66 cases, the mortality was 55, 84 per cent. Consequenthj^ \chile after cauterization of tfie icmnids made hy the Vites from rahid dogs, scarcchj two sixths {31 per cent) of the persons litten die, hj the neglect of this simple process five sixths {S4- per cent) have termi- nated tcith deaths "With relation to bites of clad or unclad parts of the body, we find the percentage of mortality for the face and head as 90 per cent ; for the hands, 63 per cent ; for the body, 63 per cent ; for the lower liml)s, 28 per cent ; for the superior, 20 per cent. As to se.v, we find 60 per cent ascribed to males, and 40 per cent to females. The consumption of the flesh and milk from rabid animals has l)een found to be without harm to human beings. The ])ercentage which the disease attains among human beings is dependent upon its extension among animals, cs])ecially among dogs. In Prussia, we find that the average deaths for fifteen years, 1820-'34, amounted to 71 yearly ; in Austria, for eighteen years, 1830-47, 58 ; in France, for twelve years, 1850-'62, 24-25 cases ; in Bavaria, for five years, 1863-67, 13*8 yearly ; for the seven years between 1868 and 1875, 18 per year ; in the district of Upper Ba- 142 THE DISEASES OF DOMESTIC ANIMALS. varia, in 1875, 8 persons died of rabies. (Bollinger, loc. cit., page 600.) " Dr. Hermann, of St. Petersburg, gives quite an interesting paper on the ' Nature of Hydrophobia and its Treatment,' in the ' St. Petersburg medicinische Zeitschrift ' for 1875. From it we learn that rabies is on the increase among the dogs of Pussia, and consequently among human beings. From tables given by him it may be observed that, in 1863, the reported cases of rabid dogs were 8, suspected 7, while the number of people who perished from hydrophobia was only 3. From that year up to 1874 there has been a varying increase, until, in that year, 49 people were bitten by rabid dogs, 12 by suspected dogs, 74 by diseased dogs, and 268 by healthy dogs, while the number of people who died from hydro- phobia was 8. Altogether, in twelve years, 2,724 people were re- ported as having been bitten by dogs, of which 1,895 were healthy, 103 suspected, 198 rabid, and 528 affected with various diseases. In St. Petersburg during that period, 25 people perished from liy- drophobia, and 22 in the Oberhoft Hospital." * The Pegistrar-General's report, of Great Britain, gives 74 deaths as taking place in England in 1874 from the bites of rabid dogs.f Hydrophobia caused the death of 47 persons in England in 1875. The "Lancet" remarks: "It is an undoubted fact that hy- drophobia has been increasingly fatal in England in recent years. The annual death-rate from this disease, to a million living, which, according to the Pegistrar-General's report, did not exceed 0'3 in the five years 1860-65, rose successively to 0*9 and 1-8 in the two succeeding quinquennials, and further increased to 2 per million in 1875. In London six deaths from hydrophobia were registered, both in 1875 and 1876 ; and in the first twenty-nine weeks of 1877, ending July 21st, nine cases had already been recorded." X Hydrophobia in France. " It is one of the duties of a French prefect to give information of the particulars of every case of hydrophobia in his department ; but, as may be supposed, these political servants very often neglect a matter which has so little party interest. For eight years, 1869-'77, only thirty-five out of eighty-six departments returned replies to the official inquiries. Of these, however. Dr. Proust, in his own name, and that of Professor Bouley, has recently issued an interesting report. Their statements show that only one half of the persons bitten by * " Veterinary Journal," vol. ii, p. 216. + " Veterinary Journal," vol. iv. X Loc. cit., vol. V, p. 385. THE DOG. 143 rabid dogs, or other animals, escape hydrophobia. The number of deaths from this cause during a period of twenty-six years, accord- ing to their notes, was 7-iO, or Httle less than 28 per annum. More men than women were bitten, but sex made very little dilference in the mortality. The liability to be bitten by young persons of from five to fifteen years of age was found to be greater than that of their seniors, though the fatality of the bite was not so great, not more than one fourth, while among aged people, from sixty to seventy, it amounted to two thirds, and above that age to three fourths. Cliildren, therefore, seem to be less readily infected by the poison, though their chances of meeting with the accident are greater. "The animals reported as causing the bites during the twenty- six years were: Dogs, TOT; wolves, 38; cats, 23; fox, 1; cow, 1; and the disease was pretty equally distributed over all seasons. Ob- servations on the incubation of the disease show that in a large pro- portion of cases it declares itself within the first sixty days of the inoculation. Thus, out of 221 attacks, 139 occurred within three months of the bite, 54 between sixty and one hundred days, 21 be- tween one hundred and one hundred and eighty days, and 3 at later periods. The disease lasted from one to fifteen days, the greater number of cases holding out about four days. " Cauterization, either by actual burning or with butter of anti- mony, is generally resorted to by French surgeons. This remedy seems to have a great influence with reference to the effects of the poison. In a given number of cases duly operated upon, the mor- tality was only 35*7 per cent ; while, out of 117 persons left to themselves, 90, or 82 per cent, died. Facts like these prove that the great evil is not the number of deaths, but the terror and anxiety caused to persons bitten by a strange dog. " The moral is, somebody ought to be made responsible for every dog in the country." * It would have afforded me much pleasure to give some statis- tics with reference to the extension of this disease among our own people for a period of years ; but, unfortunately, we have not yet arrived at that stage of civilization when authentic statistics arc critically gatiiered by the various State authorities, and in many States there arc no State boards of health. Some day (may it come soon I) we sliall have such, and the results acfjuired by the respective State boards will be published in a compact form by the National Board, in unison with the deva-stations caused by contagious and infectious animal diseases. ♦ " Vetcrioary Journal," vol. viii, p. 217. 144 THE DISEASES OF DOMESTIC AXIMALS. IS'umerous cases have undoubtedly been reported in tlie various medical journals ; but the time at m j disposal has been so limited and interrupted by other calls upon it, that it has been impossible for me to pass them in review. As has been repeatedly emphasized, rabies occurs especially in the dog, then in the wolf, cat, and fox ; also in the jackal, hy- ena, badger, as well as in the horse, sheep, goat, swine, deer, ante- lope, and rabbit ; but it is originally a canine disease. It is not definitely known when man first came to a realization of this dis- ease among animals. Aristotle, 322 b. c, makes the first undoubted mention of the disease among dogs. Xenophon, Democritus, and others, also mention it. Hippocrates, 460 b. c, has not left any- thing in the writings which have come down to us to render it cer- tain that he knew of the disease. Later authors, however — as Yir- gil, Horace, Ovid, Plutarch — seem to have been well acquainted with it. Celsus says : " When a wound resulting from a bite is not at once energetically treated, then follows hydroj)hobia, a most ter- rible evil, that permits of neither hope nor salvation for the person bitten. We should seek to withdraw the poison by means of dry- cupping, and, when possible, by firing, and, when that is impossible, by corrosion and bleeding." Galen, 131-201 a. d., describes the disease as the most fearful known to man. As a prophylactic he mentions cutting out the wound. From this time on, notwithstanding much was written upon the subject, little new was added to the knowledge of the ancient au- thors until the latter part of the last century and the first of this. There is still room for much work upon the subject. This disease, like many others, seems to be wanting in character- istic pathological phenomena, while its clinical or iutra-vital phenom- ena are so striking that he who sees them once in well-developed form will scarcely ever forget them. The most important workers in this important field have been Chabert, John Hunter, Meynell, Touatt, Hertwig, Magendie, Bruck- miiller, Bouley, Yirchow, and many other eminent scientists. The best work accessible to the American reader is undoubtedly the compilation of the English veterinary author, Mr, George Flem- ing, " Eabies and Hydrophobia," London, 1872. Whatever may have been the historic origin of this disease, it like many other contagious diseases does not originate spontane- ously, but in our day owes its origin to the bite of the rabid animal, especially the dog, and owes its extension to this means alone. It TUE DOG. 145 deserves repeatiiiij; : rcibies does not arise »pontaneoushj^ it does not originate from nothing. All sorts of theories luive been adopted and found numerous de- fenders, to sink again into oblivion. Among them may be men- tioned the intiuences of extreme beat, extreme cold, want of water, domestication, training, continement, too much ease and petting, but, most ahsurd of all, and consequently held to with religious re- spect, non-satisfaction of the sexual desires. AVhat has not been laid to this last cause by an absurdly ignorant and supei'stitious hunumity i Every form of mental or nervous excitement, superabundance of spirits, depression of spirits, poor appetite, a good appetite, too much desire for sleep, want of sleep, good spirits, evil spirits, ill temper, and about every ill which could be hypothetically connected with the sexual organs, has been attributed to abuse or non-exercise of their functions. I by no means wish it to be understood that there is not a most intimate connection between the sexual organs and numy nervous centres, but I must affirm that many of the things attributed to their influence is most absurd nonsense. The medical profession seem not only too willing to support and favor this unfounded superstition, which has been nourished by man since history's beginning. Man's selfishness has been fostered at the cost of woman's happi- ness and health, and the medical profession has done its part to su])- port it. One would think the science of comparative physiology did not exist, or that its teachings were a myth. Blind fools seeking to lead an equally blind humanity ! " Pluck the mote out of thine own eye before thou seekest to remove the beam from thy brother's eye." Some day., when what Ilaeckel calls ^^ physiogenie^''^ or wluit 1 would prefer to call funciio-getiesis, or thi genesis of the physio- h>gical functions^ becomes a naked and cold-blooded part ollinger gives some interesting statistics with reference to sev- eral eruptions of canine rabies on the Continent : '• An epizootic reigned at Hamburg, from 1S51 to 1856 ; during this period HOO cases of ra])id dogs were reported, while for twenty- three years previous not a single case had been reported. In Saxony, from 1853 to 1807, 807 cases have been recorded ; an average of 100 per year. In a total of 275,000 dogs in Bavaria, for a period of five years (1803-07), an average of 800 cases of suspected and genuine rabies were reported. For 1873, the total number of dogs reported 148 THE DISEASES OF DOMESTIC ANIMALS. in Bavaria was 292,000, and 821 cases of suspected and genuine rabies were recorded. In Vienna, from November, 1873, to August, 1875, 332 cases of canine rabies were reported. Wliile I have been unable to find any statistics of a similar trust- wortlij character for our own country, it is not without interest to know that " in 1860 we had 112,000 dogs recorded in Massachu- setts ; and further, that for the year ending May 1, 1875, 11,489 were reported as having killed sheep vahied at $10,584.53." (Flint, " Massachusetts Agricultural Eeport," 1878.) l*fotwithstanding the repeated publication of the phenomenology of canine rabies, still the subject is of such vital importance to every dog-owner, and to every citizen as well, that the more frequently it is repeated the better it is for the community at large. Phenomena of Rabies Canina. The wound occasioned by the bite of the rabid dog heals in gen- eral very quickly, leaving little or no indications of its presence be- hind, unless it has been quite an extensive laceration. The smallest abrasion of the epidermis is sufficient for infection. This fact, in unison with the rapid healing of such wounds, suffi- ciently explains those cases which have been frequently quoted in proof of the spontaneous generation of this disease, where rabid dogs have died or been killed, and then been most carefully shaved, and not the slightest indications of a wound of the cutis could be found. The period of incubation — that is, the time which elapses between the bite and the appearance of the first suspicious phenomena — ex- tends, in general, to from three to five weeks ; sometimes it extends to as many months. In the other domestic animals the period of incubation varies from two weeks to ten or even fifteen or sixteen months. As should be well known to every dog-owner, rabies canina pre- sents itself in two forms : as furious, and as still or dumb rabies. It is not my purpose to enter into minute details with reference to this disease, but rather to endeavor to attract attention to the most promi- nent symptoms in which the disease manifests itself. Writers have, however, divided the disease into three stages, and, as laymen might suppose that by these was meant three dis- tinctly marked intervals, we will at once say that such do not exist, and that, while the periods may be said to mark different stages of development in the disease, yet these stages extend one into the other so imperceptibly that no intermissions are observable. All this dividing the phenomena of certain diseases into periods is more THE DOG. 140 or less a matter of artificial classification, to suit the conveniences of the clinical teacher. These three stages have been spoken of as — 1. The melancholic or initiatory. 2. The maniacal or irritative. 3. The paralytic or lame stage. The first perceptible indication which is manifested by the bit- ten or infected dog would never lead one to suppose that the most fearful and dangerous disease known to man was in })rocess of de- velopment in the favorite of the family. It consids in little else than a change in the natural deportment of the animal. This should be emphasized — emry change in the natural deport- ment of your dog should excite your 8Ufpicio7i, and render you watchful and uneasy. No time should be lost, not only in confining your dog most carefully and securely, but in seeking the advice of the most skillful veterinary expert at your command. Among the chief initiatory symptoms are surliness, uneasiness, depression, moodiness, a continued desire for change of place, fii*st in one comer, then in anotlier ; now on the sofa, then under it : if naturally morose, the bitten dog often displays a suddenly developetl affec- tionate disposition ; on the other hand, the generally affectionate dog becomes morose and suspicious, snappish and irritable. The most insignificant circumstance will set such a dog in a fit of rage. The eyes frequently give indications of the approaching tempest, the conjunctivae or linings of the lids being injected or reddened ; the eye itself having a peculiar, unnatural expression, which, to be realized, must be seen. Even in the early part of its development an abnormal appetite is often apparetit, and is to he lool'ed vpon as one of the mod char- acteristic symptoms of the malady. The neat, delicate, and cher- ished pet of the family turns away from the usual loved tidbits, to fill its stomach with masses of filth, such as its own freces, straw, rags, and the like. The sexual functions are frequently abnormally irritated, which, has probably given occasion to the absurd theory with reference to the genesis of the disease previously considered. Such animals are more or less resistant to attempts at control, and the once true and trustworthy house-dog, or the inseparable lady's companion, suddenly develops a most marked desire to get away from the favorite door-step, or the handsome rug, and to run off over the country. 150 THE DISEASES OF DOMESTIC AXIMALS. Tlie muscular movements soon begin to demonstrate a certain want of concord ; tliey become uncertain, wavering, or weaker than usual. Such dogs frequently lick the place where the wound causing infection has been, even gnawing it, as if it itched ; but a far worse enemy than fleas is at the bottom of this trouble, and a more ener- getic remedy than " Persian Insect Powder," or great " Doctor Go- it-cure-all's Magnetic Enemy to Worms and Insects," is needed to rid the poor beast of its troubles. Without any signs of intermission, but rather with a gradual increase of these phenomena, is ushered in the so-called maniacal or " mad " period of the disease, Is^early all the previously consid- ered j)henomena are presented to us with a tenfold intensity. The whole external appearance of the animal becomes changed. The appetite is wanting ; the once docile and affectionate dog is now a fiend incarnate, seeking to bite and tear all within its reach ; the cheery bark of welcome, which once greeted the approaching master or mistress, is changed into an indescribable Jioiol. The tendency to wander from home, or break away from its fastenings, is unbounded ; the parlor pet seeks to get out, and the chained watch-dog bites and tugs at its chain in its endeavor to break away. If confined in cage, they bite and tug at the bars with the fury of a maniac, which they, indeed, fully resemble. If, up to this time, the unfortunate dog has displayed more or less respect for the master's presence and voice, it now begins to know him no more, although some cases are recorded where the ties of affection have even ruled, in a measure, such a canine maniac until life was almost extinct. Once free, they do not pursue any regular course, as if follow- ing some intellectual perception, but roam here and there, often re- turning home, and behaving like disobedient children, afraid to face the owner's displeasure. According to the previous nature of the dog is its inclination to bite during this period of the development of the malady, some being more dangerous in this regard than others. The slightest irritation, such as the presence of a stranger, another dog or animal, the presentation of a stick, is sufficient to set such a dog into a par- oxysm of rage ; these paroxysms decrease in severity as the dog becomes exhausted by disease. Such animals seem frequently, like the human maniac, to be gifted vnth supernatural strength and energy. Chains thought to be unbreakable are ruptured as if made of straw ; walls or fences thought to be unscalable are easily sprung over ; barn-doors or par- THE DOG. 151 titions so solid and thick that escape is thoii*j:ht to he impossible arc easily giunved thruii<5h, and an infuriated tiend becomes loose to prey upon the community and the balance of the animal ^vorld. Jlydrophoh'ta^ at' fear of water, is never seen in tlui d(>r. Spinola, and a singer at the Koyal Opera-IIouse, Blume, played an important role in bringing it again into use. Xotwithstanding much opposition, the consumption of horse-meat has gone on steadily in- creasing among the people, not only of Berlin, but other German cities. A most favorable influence was exerted by the order issued by the p(jlicc president of Berlin, whereby a most exact control of the horse-meat market was ordained, and the quality of the meat offered for sale guaranteed to the people. The regidation of ^larch 24, 1854, ordered : '' That no hoi-se could be slaughtered, under a penalty of a fine of five thalers ($3.75), before it had been subjected to veterinary inspection, and pronounced suitable for food." For this purpose, a legal certificate was given, which must be kept by the butcher, for a periole was subjected to disinfection, but it was too late, for four other horses, which had stood near the stall of that first named, were killed on account of glanders. It is perhaps worthy of mention, for it shows the absolute ignorance of Dr. Quack No. 1, that upon the morning that the hoi-se of the express company died, when Dr. Q. came to make his usual morning call — the horse had already been drawn away to the knackers, the doctor (?) not knowing that he was dead — a hostler renuirked to him that ' they had taken the horse out for a little' ; to which the doctor (?) answered, ' I do not think it will hurt him any. I was going to tell them that they might put him to work to-day.' On the bth of March I was called to look at a horse belonging to Messrs. , whose store was next to the office of the express company, but whose horse was kept at a different stable. This horse, on the night when I first saw him, seemed to have an attack of acute pleuro-pneumonia — remember, I had myself as yet had no case of glanders — however, glanders unmistakably developed itself in the next thirty-six hours, and the horse was killed. Follow- ing this was a roan horse in the same stable in which I diagnosed farcy, and ordered isolation. The owner M'ould not believe the fact, at least he said he did not, and called in the services of another Dr. Quack, who said, ' The horse must have fallen through some hole in the floor and made his leg sore.' This horse wa.s then sold to a Frenchman for twenty-five dollars. Quack Xo. 2 treat- ing him for a while, and I lost sight of him, to follow him up about two months later, when I was called in by a woman to see a horse in a different part of the city, and found the same horse, in a mori- bund condition from glanders. It was immediately killed and taken away. The husband of the woman had bought this horse of the above-mentioned Frenchman for thirty-five dollai*s some four weeks previously, with the assurance that he had fallen through a floor, and that that was all the trouble witli hiui. At my instiga- 172 THE DISEASES OF DOMESTIC ANIMALS. tion suit "was threatened, and the money recovered without the case coming into court. In the mean time four or live other horses that had been in the same stable with the second horse were condemned and killed, among them a fine mare worth some five hundred dol- lars. In these cases, all the horses had stood uj^on the same side of the stable with horse No. 2. After this experience the other horses were all removed from the stable, which was most carefully cleansed and disinfected, and allowed to stand empty three or four weeks. Since then no new cases have occurred at this stable. During this time the disease had become well dispersed around the city, and isolated cases were a frequent occurrence, the days being rare in which we were not compelled to condemn one or more of these animals. There was no great amount of trouble in getting most of the owners to consent to the destruction of the diseased horses, but a few would not consent, and would quietly sell the horses, so that I generally lost sight of them, as they were taken over into Connecti- cut, and there disposed of. The first one for which I was compelled to call in the services of the State Commissioners was owned in Chicopee, Massachusetts, and after being condemned and the board of selectmen notified by me, the horse was turned loose in the streets, it being summer, to wander about at will ; this fact coming to my knowledge, I decided to call in the commissioners. The horse was killed, but not before four or five others had contracted the disease from him, which were also killed. Another center of infection had in the mean time come into existence at the southern part of Springfield, due either to the carelessness or ignorance pf the previously mentioned Quack No. 1, who had been called upon to see a sick horse at a brick-yard ; this person treated the horse, and he finally died in a small stable containing nine other horses. A few days subsequent to the death of this horse, a second animal sickened, and my services were requested ; the horse appeared as if it had some foreign substance in his windpipe, owing to a drench which had been given it, and, while I was debating what to do with him, the owner said there was another sick horse in the stable, that I might look at before departure, remarking, ' D7\ Quack says it lias strained its leg.' I found it to be another good case of farcy, which let in light upon the sickness of the other horse. I ordered the horses removed from the stable, and to be separated, the stable at the same time to be thoroughly cleansed and disinfected. Five of these horses died of glanders. In all, from March 8, 1878, to March 19, 1879, fifty-six horses have been killed on account of glanders, which is a large number for a small city like ours. It is TUE HORSE. 173 but natural to afisume that many cases escaped my observation, tf7i^7 you can well realize tlie difficulties w/iich a j)ersofi iritliout the proper authority meets with. Although after June 1, 187".', I liad every assistance wliicli the mayor, Mr, Powers, and the city solici- tor could give me, the State law seemed so varj^ie to him, that he did not feel like doing what he would have liked to do, or what seemed necessary in the matter. It is to be hoped that we shall soon have some better legislation with reference ti> these matters. Foremost, it should be 80})ie one's business to look up and attend to these matters exclusively. A competent veterinarian should at least have an active c<»nnection with every Board of Health in the State, and one also with the State Board. These matters are too in- timately connected with the public health to have them governed by sejKirate boards. AVe have not yet been able to completely erad- icate the disease." The following letter was kindly furnished me by Mr. Firth, Secretary of the Massachusetts Society for the Prevention of Cruelty to Animals : Dear Sir : In response to your request to be furnished with a report of the number of farcied and glandered hoi-ses coming to the notice of the society the past two years, I herewith transmit the same, as follows, viz. : Farcied horses 2 Glandered 27 of which number twenty-four were killed at once, three were isolated by the health authorities (and, as we were informed, subsequently destroyed), while the final disposition of the remainder was never known to us. And in this connection permit me to say that the earliest operations of the society (in the year 1808) developed the frequent presence, in public places, of infected animals, and also the not unfrequent complaints at our office of men who had been duped into their purchase ; and not only were the diseased ani- mals destroyed, but in souie instances others to whom they had communicated the disease. The growing necessity for such legislation as would make it tlie especial duty of local boards of health to take cognizance of such cases, led the society and the Board of Health of this city to present to the Legislature of 1878 the draft of a bill that, it wa.s felt, would effectually aid in stamping out the disease. The result was the passage of chaj)ter 24 of the acts of that year (amended in ciiapters 160 and 178 of the acts of 1879). 174 THE DISEASES OF DOMESTIC ANIMALS. It is well known to all competent authority, and it was in evi- dence before the legislative committee, to whom the matter of a statute was referred, that the most dangerous are the Tiiost obscure cases, and, inasmuch as the general condition of an animal under those circumstances is not such as to render him unfit for labor, it is not reached by the particular statute (chapter 344, acts of 1869) our society seeks to enforce ; yet, on the other hand, the presence of such an animal in a public place is dangerous, and in such cases we make it our duty to at once bring the matter to the attention of the health boards. We feel the subject to be all-important, and trust we have been instrumental in secm*ing a measure of protection both to animals and their owners. Yery respectfully yours, Charles A. Cueeiee, Special Agent of the Massachusetts Society for the Prevention of Cruelty to Animals. I have made exertions to get reliable information from other quarters, but only received the two following letters in reply, for which I desire to publicly thank the authors. My friend and colleague. Dr. Liautard, of the American Veteri- nary College in New York city, writes ; " You ask me for a letter with regard to the extension of glanders in New York city and State. With reference to the lat- ter, I have but little to say, as my experience is entirely limited to the city of New York. " From my connection with the city Board of Health, and the American Veterinary College, I have been enabled to observe, to no inconsiderable degree, the extent to which this disease j)revail8 in our metropolis. Although it has found a powerful enemy in the Society for the Prevention of Cruelty to Animals, I am well satisfied that it exists in our private and public stables, and can be seen traveling upon our streets every day in the year. " In connection with my duties at the college, I have had occa- sion to condemn quite a number of horses brought to our free clinics. In 1876 I condemned 40 horses ; in 1877, 49 ; in 1878, 62 ; and from January 1 to March 1, 1879, 49. This does not include animals found by me in my private practice. " But the most important of all my observations with regard to glanders, the one which has no equal in all my experience, is that of the summer of 1877. I was at that time requested by the Board THE HORSE. 175 of Health to inspect the different hircalled 'doctor' (I). I had no authority to subject the entire stock to revis- ion, but if I had, I am sure that the results would have been fully equal to those of the other examinations. I am ])ei'fectly sure that I could find numerous cases of glanders among the horses of this company to-day. " Is it not indeed surprising that such a condition of things shr»uld be allowed to exist; and how can one com])reheiid that the president of a company could so overlook the interests of the stockholders as to allow so many diseased horses to remain among those of the com- pany, without continually being on the watch to prevent such dis- asters 1 Let us take, for example, the first case : 300 horses, valued 176 THE DISEASES OF DOMESTIC ANIMALS. at the loTvest estimate at $125, amounts to 837,500. The same amount to replace those destroyed makes $75,000. Add to this the loss bj food, labor, the danger of infection to other horses, the costs of cleansing and disinfection, and $100,000 would not cover the loss to the company. In spite of all this, these companies still continue to employ as veterinary advisers men entirely ignorant of the phe- nomena of this disease, or, if they know them, men who are false to their duties to the public, by persisting in treating animals they refuse to condemn even with the most manifest symptoms of glanders. " Still at times an animal is recognized by one of these practi- tioners, but the symptoms are of a mild type, the animal is in good health and condition, it represents a certain sum of money : he al- lows it to be sold to some low dealer (if he does not recommend it), or perhaps to some countryman. In the first case the horse goes to some horse-market, and is sold again to some poor but licensed vender, cartman, or cheap livery-stable keeper, unless it happens to be seized by an agent of the Society for the Prevention of Cruelty to Animals, who has it destroyed upon my certificate. In the sec- ond case the animal is taken across the river to Long Island or j^ew Jersey, spreading the seeds of this loathsome disease wherever it goes. In the face of such evidence as this is it not high time that either our State authorities, or those in "Washington, paid more atten- tion to the contagious diseases of animals, and enacted laws for the protection of our animal property, as well as human beings, from infection? Is it not high time that American veterinarians used their infiuence toward the establishment of a general sanitary vet- erinary system for the country, with its appropriate head in connec- tion with the JS^ational Board of Health at Washington, looking toward the suppression and prevention of these damaging animal pests ? " Dr. Gadsden writes from Philadelphia thus : " Deak Sir : In answer to your inquiry respecting the preva- lence of glanders in this city and State, I am glad to inform you that disease is seldom met with now in this city. I can not answer for the State, but no doubt there are many cases that do not come under my notice. " I need not tell you that I have them destroyed as soon as pos- sible after examination. During the twelve years I have been in practice in this city, I think it is safe for me to say I have con- demned two hundred (200) horses with this loathsome disease and THE HORSE. 177 had them destroyed, so yoxi will see I have not been idle. About six years ago I was called to one of our best horse-car stables, to ex- amine some ' sick ' horses that a quack was ' treating ' by contract (so much per year). I found several of them suffering from glanders in its woi*st form. I told the president of the ctfinpany the conse- quences if he kept them longer in the stable ; he ordered me to pick out the diseased ones at once, and if I remember right we destroyed between forty and tifty of them in about two weeks. I have had that same unpleasant duty to perform at four other horse-car com- panies in this city ; the quacks used to treat them for ' distemper.' "We have no special law on the subject. If I find any trouble about having the diseased horee destroyed, I call at the office of the Society for the Prevention of Cruelty to Animals, and ask them to send an officer to look after the horse, and see that it is not worked (as that would be cruel), also to see that it is not kept near other hoi'ses (as that would be cruel to them) ; so you see it very soon answers the. owner's purpose (])ocket) to have it destroyed. '* I have known of three men that died with this terrible dis- ease in this city from inoculation (through sores on their hands), while attending glandered horses and mules ; all of them suffered very much. I hope you will do what you can to teach the public the danger of this disease, as it is woi-se than this (so-called) pleuro- pneumonia in cattle, and that is bad enough." It is just the same in every State, and our national Government is as incompetent and culpably negligent as those of the States. Cattle commissions are unnecessary, and one-sided affairs. AVhat we must have are boards of animal hygiene in each State. A great noise has been made about plcuro-pneumonia among our cattle. The Government and the cattle interest most emphati- cally denied that we had any, as they do now about porcine trichi- niasis ; but finally had to admit that we have a little of the former. We should never have heard of either of them, unless some one had felt his pockets touched. Then, like cowards, we sneaked be- hind a false assertion, and said, "We have not such things." But Europeans did not believe our assertion, and finally we retracted, and admitted that we have just a few cases of pleuro-pneumonia along our Atlantic seaboard. How is it with glanders? (rlanders has much in common with pleuro-pneumonia; it is even more stealthy in its progress. Should we, unfortunately (or fortunately, I should say), ship a few lots of horses with this disease to some European country, we should probably again have the 12 178 THE DISEASES OF DOMESTIC ANIMALS. stereotyped denial on the part of the Government and the horse interests ; yet I venture to assert that there are to the thousand fifty per cent more glandered horses in this country than cattle having the contagious lung-plague, and that the former disease is extending with more rapidity among our equine than the latter among our bovine population. The government gives the people no means of knowing the facts from trustworthy statistics. The United States Agricultural Department of Statistics, with regard to animal diseases, is a dis- graceful farce. Etiology. In our remarks upon the views of different authors with regard to the nature of glanders, we have unavoidably touched upon their ideas as to its cause, which renders necessary some repetition in tliis place. "We have not time to discuss all these views in detail ; but we, as those before us, are all children of the period, and can not well sej)arate ourselves from the opinions prevailing at the time ; yet we must, in all things, ever entertain a certain degree of skepticism : to doubt is the beginning of self-education. A person who has never doubted is an ignorant believer, and has no self-knowledge — a mere puppet, unfit to be a member of any profession. So in glanders, one party has looked upon it from the iatro- chemical stand-point, looking upon an abnormal degree of oxidation, or an undue degree of acidity of the blood as the cause ; others, of the humoral-pathological school, saw its origin in all sorts of dyscrasies — not diatheses, as Fleming has written — and even from our stand-point we can speak of glanders dyscrasia, but not in the way of humoral pathology, whereby the dyscrasia was the cause of glanders, but from the natural scientific sense, the dyscrasia being a part of the disease, the same as the neoplastic processes ; that is, the result of the action of the inficiens. Others saw in it a form of equine scrofulosis ; and still others looked upon it from the neuro- pathological stand-point ; while others saw in it a form of tuberculosis, and with the eruption of the pyaemia theory, we find it classed with that kind of diseases. Nearly all these different views led to the more or less strong opposition of the contagious nature of the dis- ease, and, as we have seen, to great losses on the part of the people. Is glanders pyaemia ? The whole theory of the autochtone development of glanders is more dependent upon a few experiments with pysemic material than anything else. THE HORSE. 179 Renault and Bouley injected pus into the jugular vein of a horse, supposed to be healthy. On the sixth day pustules were observed to develop in the nose, and soon afterward ulcers. Death resulted in eight days. The autopsy gave numerous tubercles in the lungs, and ulcers of the nasal mucosa. A positive result followed the re- inoculation of another horse, with nasal discharge from this one. Laisne reports a similar result. Others report the same, but Vines exceeds all in absurdity, when he asserts that he produced glanders by means of injections of vitriol into the trachea, and other such procedures. These experiments are openly opposed by others in the same direction, and are not conformable to the results of pathological experiments in our day. In fact, it should be well known that the introduction of pus into a jugular vein will lead to processes in the lungs which, taken by themselves, might lead one to suspect glanders. Furtho'more^ in old horses, nodulated bodies are frequently met with which the inexperienced might take for tubercles — such is the condition known as bronchitis nodosa. Whether genuine tuberculosis occurs in the horse is an open question ! Lauret, Billroth, Guenther, Spinola, Gamgee, Lee, and others, have made numerous injection and other experiments, with both laudable and ichorous pus, but have in no case produced glanders. It will be observed that only in one case was glanders proved to exist by second inoculation, in Renault and Bouley's experiments. In aU the others no case of proof, or secondary inoculation, is given. Were glanders ever due to pyaemia, we should have far more proof of it than at present exists. That it could ever have been assumed to be generated in this way, must be sought in the hitherto all too much neglected fact of the long latency which the pulmonary form may have, extending over years without even a single detectable symptom of the real disease. A wound, a cold, undue exposure, or any of the causes hitherto looked upon as protopathie, may cause the acute eruption of the disea.se. The theory of the spontaneous generation of glanders again finds full contradiction in the observations of practical exj)criencc, made on islands distant from the mainland, and out of general communi- cation with it. Krabbe * reports that, on the Island of Bomholm, with over * " Deutache Zeiuchrift," i, p. 286, 1878. 180 THE DISEASES OF DOMESTIC ANIMALS. 7,000 horses, the disease is unknown, and the same is true of lee- land, with about 35,000 horses. 'No one would, I think, be bold enough to assert that these ani- mals are not as much subjected to the evil influences of exposure, poor feed, pneumonia, etc., as the horses of more favored climates. While we can not help expressing our surprise that authors of undoubted practical experience should still hold to the spontaneous generation of glanders, and give it up for nearly all other similar diseases, it is still more surprising that any person of sense can hold to the utterly illogical, metachemical, or degeneration theory by which one disease transforms itself into another, without the aid of cause. Such a thing is opposed to both common sense and experience. "What, then, must we consider the cause of glanders ? In our day, contagion, and nothing else ! A specific but unknown inficiens enters the organism and pro- duces results, in general, only observed in this disease. In accordance with tlie best results of modern pathologists, we must assume this inficiens to be of an organic, formative nature ; that is, belonging to the bacterial world. Chauveau has looked upon pe- culiar cells as the etiological moment, but this is not in accordance with our present views, though in one sense, but not in his, the bacteria are cells. Frank has looked upon some chemical material as the inficiens, and has demonstrated that the nasal discharge and blood of glandered horses possessed catalytic action, and could trans- form peroxide of hydrogen into O and H^O. Hallier, Mueller, Seramer, Zurn, and others, have all described bacteria found in the blood and secretions. Schutz claims to have discovered, cultivated, and produced the disease by inoculating them. These germs must either act of themselves, which, from the nature of the disease, is scarcely probable, or, which is more likely to be true, by means of some irritants which they themselves produce by certain unknown metachemical processes. Such an irritant is absolutely necessary to explain the slowly- developing processes of chronic glanders — the (as we shall see) gradual complication of the stroma, or interstitial tissues of many of the most important organs. It is not in conformity with our knowledge of germ-life that they can directly act in this manner. Zurn * describes the bacteria of glanders as follows : " In the blood of horses diseased with gland- ers I have found micrococci, and strings of the same — streptococci — * " Pflanzlichen Parasiten," p. 375. THE nORSE. 181 consisting of from four to eight single cells. The micrococci did not have a uniform size, yet they were always round, and had an average diameter of 0-()002 millimetres. I observed that they multiplied by fission. I saw these objects in warm blood taken di- rectly from the horse ; they were principally to be seen in and around the white blood-cells. The red cells also seemed to be in- vaded by them, but to a less degree. The smallest capillaries were often obstructed by colonies of micrococci." " In the diseased lymph-glands I also found gi-eat numbers of the same, and also staff-like bacteria — bacilli. They were either isolated or in joints of two or three members. Such objects were also present in the mucous lining of the cavities of the head." Whether these objects seen by Zurn have really any etiological connection with glanders is still an open questiun. Pure cultiva- tion, extended experiments, etc., can only finally discover the imme- diate inficiens. One must be careful not to attribute too much imj)ortance to micrococci or bacteria, found in any part of the nasal cavity or phar- ynx, or bodily cavities which connect with the open air ; fur they are not to be considered of any diagnostic value, and their isolation is too difficult a task fur our present means. The germs must be seen and collected elsewhere than here, or from open wounds, on account of these foreign admixtures — even though such material be highly infectious at the same time. The inficiens of glanders is both transportahle — by that I mean suspendible in the expired air to a limited degree — and fixed ; that is, attachable to any foreign vehicle as a purveyor and supporter of infection. With relation to the inficiens being based upon the pers])iration and expired atmosphere, we have the very illustrative experiments of Gerlach and Viborg. In these, horses having glanders were driven in cold weather, so as to get into an active perspiration ; the steam arising from them, as well as the expired air, was caught in glass receivers prepared for the purpose, and allowed to condense. Ilealthy horses were then inoculated with this material, and the phenomena of glanders observed to develop. The expired air was found to be far more active than the transpiration from the cutis. These experiments go to prove two things : 1. That the inficiens is transportable to a minor degree. 2. That the inficiens must be of 2l formative nature. No other conclusion is possible ; for, in our studies on bacteria, 182 THE DISEASES OF DOMESTIC ANIMALS. we have already learned that neither gases nor chemicals have the power of multiplication within themselves ; yet even in this case, mnl- tiplicatiou of the inficiens must have taken place to have produced infection, for Gerlach says that " only some twenty drops of the condensed fluid was used for the inoculations." Yiborg, who lived early in the century, could not well have discovered form-elements in these fluids, and it is doubtful if the microscope which Gerlach used in 1868 was equal to it. At least, he reports that none were to be seen, and concludes that the infectious elements exert a chemi- cal action, which was also Yirchow's opinion at that time. Nega- tive experiments (which, however, have always but little value in the face of positive, as the individual immunity peculiar to all spe- cies must always be taken into consideration) have been made by Ilertwig, Eegnault, and others, with reference to the expired air causing infection by means of the lungs. Diseased hoi'ses were caused to breathe into a canvas bag at one end, while healthy ones breathed from the other, yet in these cases no infection took place. These experiments are, however, only too abundantly contradicted by daily experiences. The Blood. — Numerous experiments made with the blood of glandered horses have shown it to be infectious. Schimming * gives the following resume upon the results of his and other experiments : 1. " Yenous blood from a glandered horse injected into the veins of a healthy one causes glanders. 2. " The quantity of infected blood injected appears to exert an influence upon the duration of incubatory stadium ; the stage of the disease in the animal from which the blood was taken may not be without influence also. 3. " Three months may elapse after the transfusion of such blood before we can recognize any pathognomonic symptoms. This will probably serve to explain the negative results which followed some of the experiments of Viborg, Gerlach, and Hening ; that is, the period under which the animals were kept in observation was too short to allow the disease to develop. 4. " The blood from glandered animals appears to have a less intensive action upon healthy animals than the nasal discharge, and secretions from wounded surfaces." 5. " Transfusions with such blood in dogs, cats, and swine, gave negative results." 6. " The subcutaneous injection of six grammes of deflbrinated * " Ansteckungsfahigkeit d. Rotzblutes," Dorpat, 18T5. TUE HORSE. 183 blood, taken from a glandcrcd horse, in dogs, produced the disease, which woukl seem to indicate that in this way the blood was more actively infections than by intravenous injection." Chauveau looks upon the active principle of infection in the blood as being based on certain suspended particles, leucocytes, or other form-elements, and not upon the serum. Time failed me to make any search over the literature as to the existence of tlie infectious princijsle in the secretions of the parotid and other glands, or the urine, although Gerlach casually mentions that the latter is infectious, without giving any experimental proofs. Both practical and experimental experience sufficiently prove the fixedness of the infectious principle of glandei-s. "We know that it is contained in the discharges from the nasal cavities, in tlie secretions of the cutaneous ulcers, and that whatever becomes polluted with such material, be it the harness, cribs, bed- ding, or any other accidental vehicles, may retain its dangerous prop- erties for a long time. A valuable experiment could be made as to infectiousness of the fieces from horses diseased with glanders, Teiiaciti) of the Contagium. The infectious principle of glanders retains its activity for a long time, and under varying influences. "When a vehicle — nasal dis- charge— is spread out, and quickly dried, on any hard substance, it soon loses its activity, but in stables where it pollutes the crib, etc., it retains it many months. It loses its activity on exposure to a temperature of 45° R. ; by exposure to scalding water, or by the ac- tion of chemical agents — disinfectants — such as chlorine, carbolic acid, etc. — but only when brought into actual contact with the same. Decomposition does not appear to thoroughly destroy it (Ger- lach). It seems to lose its virulence when introduced into the in- testines (as flesh) of man, the dog, swine, and hens, but while not 80 active, is still capable of causing infection in the horse. The dispersion of the infectious principle over the organism is by means of the blood and lymphatic systems. The Entrance of the Infectious Principh: into the Orgajiism — that is, Natural Infection. Experience goes largely to prove that while the infectious ele- ments of glanders have a fixed character, that is, are not capable of being taken up by the atmospheric current, and carried to any great distance from the point of original generation, or lodgment, still that, 184: THE DISEASES OF DOMESTIC ANIJIALS. in bj far the greater number of cases, infection must take place hy means of this principle when suspended in the atmosphere ; that is, by means of the expired air from glandered horses. Were this not so, cutaneous glanders (farcy) would be far m.ore common than it is ; in fact, it should, under this cu'cumstance, be the j)rimary form. Again, were the infection not generally due to a suspended principle, we should have far more cases of ulceration in the lower or exposed parts of the nasal passages, which is rare, while deeper seated ulcerations are more common. Again, that a suspended principle is commonly the cause of in- fection, is proved by the numerous cases of pulmonary glanders which occur with little or no nasal complications ; in the numerous cases of pulmonary glanders, accompanied by cicatrices in the mu- cosa of the bronchial tubes, trachea, and pharynx, all indicating the long continuance of the disease, but, with eecent complications in the super-nasal parts, with no evidence of older complications. Disposition. — Immxinity. As in every other contagious disease, not every horse exposed to infection has glanders. Of 138 healthy horses which Lamirault caused to stand among diseased ones, and to be cleaned, etc., with the same utensils,, and to work with the same harnesses, only 29 be- came diseased — 28 with glanders, 1 with farcy. According to Lydtin, 40 to 50 per cent of the horses exposed to natural infection became diseased. By inoculation of 23 horses, only 8 became infected. The almost invariably fatal character of the disease does not allow us to judge whether an acquired immunity is possible or not, by animals that have once had it. "With the present French mania for all kinds of vaccinations with cultivated virus, we shall probably hear of a modified form of glanders being able to give an acquired immunity to natural or fur- ther infection, at least for a time. I always stand skeptical to all such assertions — ready to believe, but doubting until the evidence is overwhelmingly ^w or con. At present I do not believe in the generalization to which the few Pasteur vaccine experiments have led. Inoculation for glanders is no new thing, but has as yet always signally failed. Furnival,* an enthusiastic Briton, claims "to have cured seven bad cases of farcy by inoculation," and was anxious to * "Fleming's Veterinary Journal," vol. x, p. 51. THE nORSE, 1S5 continue this method of equine salv;ition, but, as we have heard nothing more from him in this direction, we may conchide that there are backsliders in his equine salvation army. Phenomenology. According to duration, glanders may be spoken of as acute or chronic ; according to seat, as nasal, pulmonary, or cutaneous glanders (farcy). Pulmonary glanders can occur -without either the nasal or cuta- neous forms being present, but it is very questionable if cither of the latter can occur without evidences of pulmonary complications. Chronic glanders is the common, acute the rare course which the disease assumes. Incubation. — D u ration. In inoculations the incubatory period is generally from three to five days, but in natural infection it is very hard to say, the authori- ties varying from five to six days to as many weeks. In that form which is known as chronic glanders, a period of apparent latency may exist for months, yet even here there must be a period of incu- bation. Acute glanders may terminate in from ten to fifteen days, while the chronic variety may continue for months or even years, how many is an open question. Chronic glanders terminates invariably with the acute form, but when the acute variety follows known infection, it never assumes a chronic character. Acute Nasal Glanders. Under this name we usually find both the acute processes in the mucous membranes of the head an"<^Gtice. Such men flatter the friends of the sicJc, are very attentive, take less pay, are boldfaced, and never attribute the poor results of their practice to their own ignorance. The educated practitioner must flee the company of such men as a thicTcet full of ravenous animals. The reward of the practitioner must be ordered according to the means of the pa- tients. It is dishonorable to demand pay of Brahmans, relations, friends, and the unfortunate. The doctor shall take no other pay from women than refreshment. The kings have especial doctors^ who take part in the wars ; others must be present in the kitchen to prevent poisoning." In the " Laws of Manu " it is written that " the doctor who mishandles animals shall receive the lowest, while he who mistreats human beings shall receive the highest punishment." The Indian doctors possessed but little real knowledge of anato- THE HISTORY OF VETERINARY MEDICINT:. 0|7 mj. They, however, made studies upon the huuian body, hut in a singular and unfruitful manner. The body must be that of a healtliy man, not too old, not deformed, and from a person that had not died from poisoning or tlie devastations of a long and wearing dis- ease. The body nmst lie for seven days and nights in the watere of a brook, and then the outer parts must be removed by brushing with twigs. Instead of a description of the different parts of the body, we find numerous calculations, measurements, and classitica- tions of the parts. According to Susruta, the human body consists of seven elements, and seven skins or membranes, three hundred bones, twenty-four nerves, three fluids, one hundred and seven joints, nine hundred ligaments, ninety sinews (the nails were looked upon as the endings of the same), forty principal vessels, seven hun- dred branches, and five hundred muscles. The navel was looked upon as the central point of the nerves and vessels. The cardinal elements, air, gall, and mucus, find frequent mention. The air is situated below the navel, the gall between the navel and heart, and the mucus above the heart. To the elements making up the human organism was also added ether, out of which sprang light, out of light generated water, and out of them both earth. The seven or- ganic products of these cardinal elements were the chyle, blood, flesh, cellular tissue, bones, the medullary substance, and tlie semen. The blood generated from the chyle. The chyle is an aqueous fluid ; it becomes red in the spleen and liver. Milk formed the exclusive article of food to the end of the first year ; to the third year, milk and rice ; and to the fifteenth, rice alone, when a mixed diet was allowed. Tiie best means for the preservation of health are the weekly offering of an emetic, montlily a purgative, and twice yearly (at the change of seasons) blood-letting. Diseases were classed as natural and supernatural. Diseases were frequently caused by sin. The most important diseases were due to a want of or surplus of action of the cardinal elements upon the jihysiological elements— the chyle, blood, etc. The predominance of one cardinal element over the others gave rise to the different temperaments. The soul seeks to equalize the disharmony, dyserasies of the cardi- nal elements, by which disease is produced. Disease is, therefore, a disturbance of tlie activity of the soul occasioned by abnormalities of the cardinal elements. The air contained in the body is the cause of eighty different diseases. To these belong the diseases of the nerves — tetanus, trismus, chorea, also leprosy. Among the dis- eases of the urinary organs one is surprised to find that a sweet and albuminous urine is mentioned. Diabetes was considered incurable. 218 THE HISTORY OF VETERINARY MEDICINE. A knowledge of poisons and their action is an indispensable part of the education of the doctor, as the food is often poisoned by the enemies of the ruler, wicked women, and unthankful servants. These ancient Indian doctors seem to have been well acquainted with hydrophobia, as the action of the bite of the rabid dog, fox, jackal, wolf, bear, and tiger. The treatment consisted in appro- priate local applications to the wound, and the inward offering of antidotes. In this regard Wise * says : " The Bites of Mad Dogs. — When dogs, jackals, foxes, wolves, bears, or tigers, become mad, they foam at the mouth, which re- mains open, their tails bang down, they do not hear or see well, and saliva flows from their mouths. In such a state they snap at and bite one another. The part that is bitten becomes senseless, blood flows from the wound, which becomes black, and other ap- pearances are observed, as after a wound with a poisoned arrow. The ])erson hitteii makes tJie same hind of noise and movements as that of the anim^al which has bitten him. IVheii such a person sees the shape of the animal which has hitten him, either in water or in a glass, it is an unfavorable symptom. It is also iinfavorahle wJien the person is afraid of water, and dreads either seeing or hearing it. This is called hydrophobia, the fear of water. When the per- son dreams of the rabid animal, it is unfavorable. Toward the ter- mination of the disease the person is convulsed, becomes insensible and powerless, and dies." " In all such cases the first part of treatment should be to scari- fy the part and squeeze out the blood, after which the p>art is to be washed and burned by means of hot ' ghee^ Then apply to the wounded part a mixture of certain antidotes, and give old ' ghee ' internally. Errhines are also to be given with the milk of the arka- plant, Calatropis giyantea. Susruta recommends the following, which is to be used both internally and externally : Take of ' Shir- isha,' ' Kustha,' ' Haridra,' ' Shita,' ' Sharshapa,' of each forty ratas, mix in a pint of water, and boil until reduced one fourth. During the treatment the patient should be kept in a cool situation, without any water. When the symptoms disappear, the person should then bathe, and on the third and fifth days the above is to be administered in half the dose given at first. He is then to take rice and milk. It is recommended in these cases to act powerfully upon the system by strong medicines before the poison has produced its constitu- tional effects. After the infliction of the wound, and before it has * " History of Medicine in India," vol. i, p. 280. TDE HISTORY OF VETERINARY MEDICINE. 219 produced any <;oncrul effects, the free use of water in batliin«j^ is reconiiuended, anil the bowels are to be afterward opened by purga- tives and emetics, followed by errhines to clear the passages." The perfection to which the Aryan doctors developed the prac- tice of surgery is surprising indeed. They made many useful instniments, catlieterized the bladder, removed stones, punctured the abdomen, originated plastic operations upon the nose, ear, and lips, set fractured bones, performed " laparotomy,'' and made skill- ful operations upon the eye. The Caesarean operation was per- formed on the death of the mother to save the infant. The beginners of veterinary medicine, or, rather, those who firet practiced the liealing art upon animals, were undoubtedly the shep- herds and lierdsmen, who were intrusted with their care. This em- ployment was frequently followed in families, and the results of experience thus gained were doubtless transmitted from father to son for generations. These early veterinary empirics must fre- quently have come in friendly intercourse, and thus the results of nnitual experiences were interchanged and criticised ; so the fund of empirical knowledge gradually increased, until the sum of these experiences was linally gathered on parchment, and then, with the birth of printing, into books. While many of these men were un- doubtedly keen observers of nature, there is no doubt that they were also great admirei's of the marvelous, and equally superstitious, so that many most absurd superstitions as to the causes of disease crept into their sayings and writings. Charaka is said to have written a work upon the diseases of ani- mals, but I have vainly searched for any quotations from it. That the Jews and Egyptians were acquainted with many forms of animal disease must be known to every reader of the Bible, for the plagues with which Jehovah punished the Egyptians, and through which they were robl)ed of tlieir cattle, are most graphically described by Moses. The oldest Egyptian monuments bear upon them carvings illustrating the treatment of animals. The Greeks possessed, at a very early date, a more or less ex- tended literature with reference to the treatment of the diseases of animals. With the blooming of Greek culture, medical art took an active move forward. IIij)pocrates, 4<50-377 n. c, the honored father of medicine and the compiler of all the knowledge which ex- isted up to his time, was quite well acquainted with the coarser anatomy of some of the lower animals, and we find several notices in his writings which warrant us in assuming that he was not unac- quainted with some of their diseases. In speaking of hydrothorax, 220 THE HISTORY OF VETERIx\ARY MEDICINE. or water in the chest, lie says, " It is a disease which is also fre- quently met with among oxen, sheep, and swine." * He had proba- bly met with it in these animals much more frequently than others, because of their frequent use in the sacrifices at the altars of the gods at the Hellenic temples. In another place he says : " In cattle, the thighs are apt to become dislocated at the hip-joint, when they are particularly lean, which occurs at the end of winter, at which time they are particularly subject to dislocations. Homer has well remarked that of all beasts oxen suffer the most at that season, and especially those employed at the plow. In them, there- fore, dislocations happen most frequently." f The influence which Hippocrates exerted upon medical science for a thousand years after his death is scarcely appreciated by the public, and by far not sufficiently esteemed by his successors of the present day, many of whom have not read his works, notwithstanding their accessibil- ity to English readers, by the above-mentioned excellent and critical edition, for which we are indebted to the Sydenham Society for publication. The young practitioner of to-day seems to be carried away by the desire for new things, and all sorts of iiew remedies are eagerly sought after and experimented with, much to the neg- lect of the study of the fathers of medicine. The present genera- tion is emphatically one of research, but it is a great and harm- ful error to think that the microscope and crucible can reveal all that is to be known of disease. The works of the fathers of medicine often excelled those of the present day in clinical ob- servation, in the exact description of the intra-vital phenomena of disease, and in detailing the results of experiences gained at the sick-bed from the use of medicines. At present a healthy re- action is beginning in this direction, and the microscope furor is being toned down within the limits of practical possibility, notwith- standing a Kew York enthusiast purposes to tell us whether two given persons are compatible for marriage, so far as the production of healthy offspring is concerned, by the microscopic appearance of the granulations in the protoplasma of the white or colorless blood- corpuscles. That such an assertion is but the utterance of a vision- ary and untrustworthy observer scarcely needs to be mentioned. Hippocrates,:}: also called the great, is said to have come from a family of doctors, descending from yEsculapius and Ilerucles. Little is known of his life, many relations concerning the same being mixed up with myths and impossible extravagances. He was, how- * Haeser, he. cit., p. 173. f "Works, Sydenham edition, vol. ii, p. 575. J Wunderlich, " History of Medicine." THE niSTORV OF VETERINARY MEDICINE. 221 ever, greatly hunoret-l, and both j)niotlcL'(l and taugLt medicine among his countrymen, lie wa.s the author of many books, but few of those which have come down to us are looked upon as genuine ; many others attributed to him c-untain much of his teach- ing, however. It is a mistake to designate him as the founder of a new system of medicine : he was simply a harvester in the lields of medicine, but also a keen observer of the phenomena of disease. He himself says that '' he who scorns or throws away the past, and seeks to make a new way and new theories, or thinks that he has found such, is either a deceiver or is himself deceived " — words which should not be without due appreciation by the JSsculapians of the present day and generation. The followere are many, the discover- ers of new truths but isolated phenomena in the march of human progress. He was a grand observer of nature. lie made no new system, but was bitterly op]>osed to hypotheses. He looked uj)on the living organism in the Epidoclesian sense, as composed of four cardinal ele- ments, which he named blood, mucus, black gall, and yellow gall. His pathology was simple in the extreme. When these cardinal elements bore a proper relation to eacJi other in the living organism, a crasis or normality existed ; any disturbance of this normal condi- tion, any preponderance of one of these elements, either as a whole or locally, produced abnormality, dyscrasis. He laid but little value upon theoretic discussions : " When any one can give a better ex- planation, it suits me equally well ; such ability is but the result of a glib tongue." His anatomical knowledge was quite limited, and he seems never to have made studies upon the human body. He laid great stress upon the value of knowledge with regard to all the ex- ternal phenomena presented by the diseased organism. The condi- tions, in disease, of many internal organs, did not, however, escape his attention — such as the swelling of the spleen, and its subsequent retraction, in various forms of infectious disease. " The practitioner should be able to recognize the conditions presented to him, without the necessity of referring to the relations of the patient ; ... if perspiration occurs in a fevered patient, without remission of the fever, the disease will be lengthened ; the fever increases when the teeth have a viscid coating; ... a disea.'^ in which sleep has a deleterious influence is deadly ; when the patient is, however, im- proved by sleep, it is to bo looked upon as a favorable symptom ; . . . sleep and sleeplessness, when present to an abnormal degree, are evil symptoms ; . . . when a convalescent person has a good appe- tite, but does not improve thereby, it is a bad symptom ; ... he 222 THE HISTORY OF VETERINARY MEDICINE. who would correctly prognosticate as to who will die or who will recover, whether the disease will be of long or short duration, must know well all the phenomena, and be well versed as to their re- spective value." His manner of treatment was well considered, and he generally avoided heroic means. He placed great stress upon the value of dietetics, which should be adapted to the individuality of the pa- tient, his constitution and habits. He was, according to his idea of the cardinal elements, much addicted to the employment of local means, by which the supposed centralization of a given element was to be equalized or the surplus removed ; therefore, we iind in his writings many directions for local bleeding and applications. He invented quite a number of surgical instruments; performed tre- panning of the cranium, set bones, and reduced luxations. He highly prized cauterization, and his last aphorism reads : " What medicine will not cure, the iron will ; what the iron will not cure, fire will ; what fire can not cure, must be considered as incurable." But, above all Greek writers of antiquity celebrated in the field of medicine, none equaled, in a knowledge of the anatomy of ani- mals, that mighty intellect which has been the wonder of humanity for generations, and which had not its equal in the arena of natural science until long after the middle ages — Aristotle. " Aristotle was born at Stagyra in Macedonia, in the year 384, and died 326 b. c. He was undoubtedly the greatest thinker of his time, and united in himself all the knowledge which then existed. His father, Nichomachus, was body-surgeon to Amyntas III, of Macedon, the father of Philip. At seventeen years of age, Aris- totle went to Athens to study under the immortal Plato, who recog- nized his great genius, and called him the brightest spirit of his school. Aristotle soon separated himself from his teacher, and be- gan to oppose the doctrines which he taught ; he went to Mace- don, and became the tutor of Alexander the Great. "When the latter went upon his conquests into Asia, Aristotle returned to Athens, where he appeared in the character of teacher, Alexander supporting him, and for his studies giving him the immense advan- tages offered by the collections of curiosities made in his foreign conquests. The results of his investigations are collected in his writings and speak for themselves. . On Alexander's death the ene- mies of Aristotle became powerful enough to cause his banishment from Athens ; he was declared a heretic, a disbeliever in the gods, and so deadly was the pursuit of his enemies that he finally killed himself in his sixty-third year. His body was brought to the place TEE HISTORY OF VETERINARY MEDICINE. 223 of his nativity, his eountryinen erecting a nionuuient to liis memory. Aristotle may be justly styled the founder of zoiitomy, the anatomy of animals. His writings, subsequent to his death, suffered a rather chanireable destiny: thev fell at tirst into the hands of his heirs; then they were buried and barely escaped destruction from decay and worms ; afterward they were conveyed to Athens, and finally to Rome by the Romans on the capture of Athens, and from there they have been dispersed over the world, but not without many falsifications and changes." * His anatomical descriptions,^ so far as they had reference to man, were limited to topographical descriptions of the external parts ; the formation of the internal was, as he himself says, little known, but they were described according to analogy, from the ex- aminations of similar organs in the lower animals. lie describes the brain and its membranous surroundings, as well as its ventri- cles, cavities ; also the optic nerves in their passage from the brain to the eye ; on the other hand, he denied any connection between the brain and the ear ; he describes also the larynx, uvula, epiglot- tis, the trachea and its bifurcations in the lungs, also the Eustachian tubes, but had an incorrect idea with reference to the connection between the heart and lungs; he described the oesophagus, and its passage into the stomach, as well as the extension of the latter to the intestines ; also the epiploon and mesenterium, Kotwith- standing much study, it was impossible for hira to come to any defi- nite conclusions with reference to the vascular system ; he looked upon the heart as the center of the vessels, but described only three cavities in that organ, missing the septum between the auricles; he notices the aorta and vena cava, as well as the main arteries and veins of the head and neck ; also the diaphragm, liver, gall- bladder, kidneys, and their pelvis, the ureters and veins of the kid- neys, tlie urinary bladder and urethra, the testicles and their vessels, as well as the same organs in the female, and the uterus. It is doubtful, however, if he knew of the relation of the secretion of the kidneys to the l)laddor, or of the organ at present considered as the rudimentary male uterus. Aristotle had very imperfect ideas of the circulation : the blood was generated in the heart and from there dispersed over the organ- ism ; it sprang, coagulated, out of the vessels, and was of varialjle color. The respiration served as a cooler to the organism — its or- gans are the lungs and gills ; his incorrect idea of the connection * Schracder-IIering, " Bibliopraph. Lexicon f. TliicrarTte," p. 16. f Aubcrt and Wimmer, "Aristotle's Thierkundc," Lcipsic, 1868. , 224 THE HISTORY OF VETERINARY MEDICINE. between the lungs and heart gave him the conception that the air came into the heart ; he compared the lungs to an air-sac, and does not seem to have had any conception of the changes which take place in the blood by their means. His views with reference to digestion, and the changes which the elements of the organism un- dergo, were very crude indeed. His description of the senses, see- ing, hearing, smell, and taste, is surprisingly clear and explicit. He looked upon the muscles as the organs of sensitiveness, and not of movement ; the sinews as motor organs, and the heart as the cen- ter of movement. He made an astonishing number of clever obser- vations with regard to the generation and development of animals, and studied the same in the hen's e^g ; the formation of the heart, brain, and eye, allantois, and chorion ; the duration of gestation in many different species. His observations with reference to the instincts of animals are often surprisingly correct, as well as with regard to the variations in their habits of life. Aristotle also de- scribed quite a number of diseases among animals, and, as the sub- ject is not without instructive interest, I take the liberty of giving a very free translation of them here.* " As to the diseases of quadrupeds, swine have three different diseases. One is known as ' bronchos,' and consists in an inflam- mation of the air-tubes and the masticating organs ; it, however, frequently complicates other parts of the porcine organism ; some- times the feet become diseased, and at others the ears. The dis- ease develops rapidly, the swine soon losing their appetite. The herdsmen know of no other treatment than to cut out the diseased part at once. Aside from this, two other diseases occur in swine, both being known by the name of ' kraura.' In one of them we may perceive pain and depression of the head, and in the other diarrhoea is the most frequent phenomenon. This last is reputed to be incurable ; the first is, however, cured by rubbing the snout with wine, as well as washing the interior of the same with that material. In this disease, also, but few recover, as it generally ends fatally in from three to four days. Swine suffer most from ' bronchos ' when the summer is very fruitful and the swine very fat. Mulberries and plenty of warm baths are said to have a beneficial effect ; scarification of the tongue is said also to be re- sorted to. The swine are measly when the flesh of the limbs, neck, and shoulders is soft; in these places the measles must be sought for. The flesh has a sweet taste when it harbors measles, at the same time it is soft and watery. One can easily tell when * A. and W., chapters xx, xxii, p. 181. THE niSTORY OF VETEIUNAKY MEDICINE. 225 the swine have measles, fur tliey are to be fouiul under the tongue. Measly swine can not keep their hind-feet quiet ; they lose the measles after having fed upon ' tiplia,' which also helps their con- dition. The best food to nourish swine is peas and tigs, but one must not give them one kind of food, as mixed diet is best for them. It is &i\\d that acorns are greedily devoured by swine, but that they make them have soft and watery flesh. AVhen in a pregnant condition too many acorns cause them to abort, as they also do sheep. So far as we know, swine are the only animals that harbor measles. '• Dogs also suffer from three diseases, known as ' rabies,' ' ky- nanche,' and ' podagra.' Rabies puts them into fits of rage, during which they bite furiously, and all animals bitten by them when in this condition also become mad, loith the exception of man. This disease kills the dogs, as well as all animals bitten by them, with the exception of man. ' Kynanche ' is also deadly to dogs, and from ' podagra ' but few recover. Camels are also subject to rabies. Of all other animals, the elephant alone is exempted from this disease, but it is subject to tympanitis." ** Cattle living in herds are subject to two diseases, known as ' podagra ' and ' krauros.' In the firet, the feet become swollen, but they do not die from it, nor do they lose their hoofs ; they be- come better when one covers their horns with hot pitch. In ' krau- ros,' their breath is hot and respiration accelerated ; this is called fever in men, but ' krauros ' in cattle. The signs of this disease are drooping ears and loss of appetite ; they die rapidly, and the lungs are gangrenous upon examination. '* Horses which live \\\>o\\ pastures are subject to no other disease than ' podagra.' AVhen afllicted with this disease they sometimes lose their hoofs ; but, when this is the case, new ones soon develop, for, as the new hoof grows down, the old one is shed. Among the signs of this disease is swelling of the right testicle, or a corrugated condition of the skin between the nostrils. They are also subject to a disease which is called ' eilos,' which is characterized by the animals placing the four feet together under the body. AVhcn horses go for some days without eating, and then become crazy, one has to resort to bleeding and castration. They arc also subject to ' tetanus,' a disease by which all the vessels, as well as the head and neck, become stiffened, and the animals move stiff-legged. They soon become purulent. Another disease to which they are subject is called ' krithian,' indicated by a soft palate and hot breath. These diseases are incurable, when they do not cease of themselves, which 15 226 THE HISTORY OF VETERINARY MEDICINE. is also the case in tlie disease called ' nympliian,' in which the horse becomes stiS when one blows up its nose, or depresses the head ; when any one tries to ride them they go in circles until stopped. They always depress the head when rabid. Other signs of the same are that they depress the ears upon the mane, and again elevate them ; that they become weak and snort much. Conditions con- nected with pain of the heart are also incurable : in this the animals have tucked-up flanks, or the bladder becomes displaced, which is easily recognized from the inability of the horse to micturate, and that they draw their legs up and stamp with their feet. According to those who should know, horses and sheep suffer from all the dis- eases common to man. A poison known as ' sandarac ' kills not only the horse but all draught-animals. It is given in water. A pregnant horse aborts when it smells the smoke from a blown-out candle ; the same effect is also occasionally observed in women when in the same condition. Horses love meadows and swamps. They drink gladly of dirty water, and when the water is clear they stir up the bottom with their feet, and then bathe in it, for these animals generally bathe gladly and love water. Cattle, on the con- trary, do not drink freely of water which is unclean and warm. " The ass suffers especially from one disease, which is known as ' melis.' It at first attacks the head, a viscid, yellow slime running from the nostrils ; when the disease extends to the lungs it is deadly, but when limited to the head it is not so. Of all animals of its kind, the ass can bear cold the least, and thrives, therefore, in warm climates. " The elephant is subject to tympanitis, and when thus afflicted can neither micturate nor pass faeces. When it eats earth (?) at in- tervals, it becomes weak ; but when it eats it constantly, it does not seem to harm it. Sometimes it swallows stones. It also occasion- ally suffers from diarrhcBa, and is healed by giving it warm water, and hay which has been dipped in honey. When suffering from want of sleep they become weak, but strength returns when the shoulders are rubbed with warm water, salt, and oil. When troubled with pains in the shoulder, they can be helped by placing roasted pork iipon the afflicted part. Some elephants will drink oil, others not. When a fragment of iron penetrates their body, it is said that it can be driven out by giving them oil, but those who will not drink it willingly must be given the oil mixed with roots." The fame of the noted Greek general, Xenophon (349-259 b. c), is not alone limited to the remarkable retreat of the brave ten thou- satid, for his writings upon the horse and horsemanship have given THE niSTORY OF VETERINARY MEDICINE. 227 Ijiin a no less lastiii a. d., but was again called to Ivonie by the enn)erors IMarcus Aurelius and Lucius Yenis, where ho remained until his death, giving public lectures, and busied with his studies and writings. lie was the most exten- sive medical author that has ever lived, and appears to have begun his authorship even as a boy. It has been estimated that he wrote some four hundred books, some of them being quite large. He was, indeed, a polyhistorian, and a man of astonishing learning; many of the views of medical authors antecedent to his time are only known to ns through his writings. lie possessed great analyti- cal and critical ability ; he had seen much himself, and investigated much, and possessed a highly systematic mind, clearing medicine, as it then existed, from nuich of the superstition and nonsense with which it was burdened. His anatomical knowledge was derived in part from the writings of llerophilus and Erisistratus, and in part from his own dissections, which were made largely npon apes. It had not been possible for a long time to make studies of anatomy upon the human form divine, and this age, which did not pause to sacritice thousands of human beings at brutal gladiatorial combats, still could not oUer one for the good of humanity and the advance- ment of knowledge. Only once, during the German war of Marcus Aurelius, was it allowed the doctoi-s to dissect a human body, but they did not get beyond the situation of the intestines, ^t'ever- theless, the writings of this great doctor remained for a thousand yeare the source from which a knowledge of human anatomy was drawn, and it was only by earnest endeavors, supported by actual inspection, that his great authority was finally shaken. Galen is accredited with saying that " the education of a doctor was incom- plete without a knowledge of the processes of disease among the lower animals." The writings of the celebrated Roman veterinary authors, Cato, Varo, Columella, and Vegetius, which are mostly cumpilations from earlier writers, may be found collected in " De Rei Rusticse," a good cditidU of which was given out by Gesner in 1735: cojiies of this work may l>e found in some of our medical and public libraries. These writings contain descriptions of some diseases, much of which is altsurd and ndiculous, in the light of the ])resent day. *' Marcus Fortius Cato,* the most ancient of this quartet, was bom at Tusculum, or Tivoli, 234, and died 149 b. c. He was of a plebeian family, ami served as a soldier under Fabius Maximus, but * Schracdcr-llering, loc. cU., p. 76. 230 THE HISTORY OF VETERINARY MEDICINE. by his energy of character elevated himself to positions of the high- est honor. He became a clever general, jurist, and orator. On ac- count of his steadfast morals, and constant enmity to human frailties, he acquired the surname of 'the Censor.' He was an enthusiastic opponent of Greek doctrines and art, and has the honor of being the first Koman who wi'ote upon agriculture : in these writings we ob- serve a crude development of veterinary medicine. His writings have been frequently printed and translated into several European languages." "Lucius Junius Columella* was born at Cadiz, Spain, in the reign of the Roman emperor Clandius, about 42 a. d. He had fre- quent recourse to the writings of Celsus, and did much for the development of veterinary medicine. His writings upon the dis- eases of the horse are not inconsiderable, but his descriptions of those of cattle are by far the best which we have received from antiquity." " Publius Renatus Yegetii f (fourth century a. d.) is noted as the most erudite among the early veterinary authors. He appears to have possessed no inconsiderable degree of knowledge with refer- ence to the diseases of the horse and their treatment, as well as a scholastic acquaintance with the writings of his Greek and Roman predecessors, and some of human medicine, and to have held affec- tionately to its antiquated theories and methods of practice. I have heretofore said that ' veterinary medicine has heen but a parasite clinging to human medicine for support.' His writings bear the characteristics peculiar to his time, but are distinguished from those of many of his contemporaries by being written in more scholastic Latin. He used the writings of Absyrtus, but complains of the illiterate style in which they were written. As Vegetius often speaks of the Huns and their horses, and as these people spread over the Yolga in 374 a. d., it is evident that he must have lived in the fourth or early in the fifth century, at a time when the Latins also understood Greek. He describes the diseases according to the parts afflicted, and varies but little from his Greek predecessors. It is to his credit that he was the first veterinary author who endeav- ored to bring some order out of the chaos which had until then ex- isted, and endeavored to formulate some general principles for the diagnosis and treatment of animal diseases. His first two books treat upon the diseases of the horse, the third upon those of cattle, the fourth gives a general description of the bovine and equine form, and the composition of many medicines ; among the latter are * Schraeder-Hering, loc, eit., p. 88. f Ibid., p. 440. THE HISTORY OF VKTERINARY MEDICINE. 231 many which are nio-st hulicrous. AVhik' thu therapeutic knowledi^e displayed hy ^'e^etius is frequently good, his knowledge of anatomy was most insignitieant, especially of that which was then known in human medicine." It is in the writings of these authors that we iind the words "veterinaria" and " veterinarius" first appearing, indicating the Latin oritrin of our words ''veterinary" and "' veterinarian." The art was also called '* mulo-medicine," and Vcgetius styles himself "Vegetii Renatii sive Mulo-medicinae." It is at or about this period that we first find intimations of horseshoeing among the Romans, a practice they seem to have borrowed from the Germans and Gauls.* Veterinarii are also mentioned as attached to the Roman cavah-y, and attending to the health of the animals used at the circus at Rome. During this period numerous pests carried devastation and mis- ery among the Romans and their tributary tribes; the domestic animals likewise suffered from similar scourges. No writer of the period has given to posterity so classical a description of these devas- tations among animals as the poet Virgil in his " Georgics." I take the liberty of transcribing a few appropriate verses of the same from Mr. Fleming's " Animal Plagues " : " Not whirlwinds from the sea so frequent rush, Big with storm, as pests 'mid cattle rage. Nor individuals sole disorders seize, But, suddenly, whole flocks, with every liope, At once, and, from the youngest, all the race. "... From tainted air arose A dreadful storm, inflamed by autumn's heat, And gave to doatli all cattle, tamo and wild. Corrupting lakes, poisoning the grassy food. " Hence, midst the springing grass, young cattle die, And yield their gentle lives at loaded stalls; Ilenco, madden fawning dogs, and the sick swine. With suffocating shake and panting cough, give up their lives. "Lo! a^ tlie hull under the plowshnre smokes, He falls, and vomits mint'led foam and gore, And makes his final groan; • .\nr one dofirint; to road a most interesting archfrolngical Ptudv, should not fail to obtain Mr. (Icorf^c Fleming's " Horsoshoos anil Horspshooing," which is a work more suit- able to gi-neral education than for instruction in horseshoeing, though the latter part does not fail in this particular. 232 THE HISTORY OF VETERINARY MEDICINE. The plowman sad disjoins the ox that mourns his brother's fate, And leaves the rooted plow, his work half done. Move him not now, nor stream through rocky bed, That pure as amber freshens all the plain. His flanks are all relaxed, and his dull eye A stupor covers, and to earth his neck Down rushes with the heavy weight it bore. " What profit, then, then* service and their toil ? No change of food affords relief, And art, implored, destroys." I have endeavored, briefly, it is true, to sketcli the history of veterinary medicine in antiquity, with what success it must be left to the reader to judge. The works which we have already alluded to remained the fountain th" t supplied nourishment to compiling authors for nearly a thousand years: for it is not until the middle of the thirteenth century that any work of original importance was added to our literature. In the tenth century, the Emperor Con- stantine Porphyrogenitus, 911-951 a. d., instigated a compilation which included about all the works which had until then aj)peared. Schraeder, in his biographical lexicon, says of him that "he was the son and successor of the Greek Emperor Leo. To him we are indebted for about all we know of veterinary medicine uj) to his time. He favored and nourished science with all his energy, caused public education to be given and schools to be erected, which he made subservient to the uses of the state. He gave his whole at- tention to the academy at Constantinople, and sought to increase its usefulness with all the resources at his disposal. As author and polyhistorian, he gathered books from all parts of the earth, praised the diligence of compilers, and caused most valuable extracts to be made from innumerable writings upon history, agriculture, and medicine, a task which had never before been undertaken, and even veterinary medicine was not neglected." Haeser * says of this part of the work, which was entitled the " Hippiatrica," that it consisted mostly of the letters of Absyrtus, Emulus, Hierokles, Pelagonius, Theomnestus, Tiberius, Anatolius, Archedemus, Hippasius, Tetrippus, and Stratonicus. It first ap- peared in a Latin translation, under the title " Yeterinaria Medi- cinse," libri II, Joh. Ruello, interp., Paris, 1530. An edition in the original Greek text was published at Basel, 1537, under the title " ToDV L'mnarpL'xpiv ^t^Xia Sua)." Translations of the latter appeared in Italy, 15-13 ; France, 1563 ; Germany, 1571. It is of general in- * Loc. cit., p. 546. THE HISTORY OF VETERINARY MEDICIXE. 233 tercst that Leontius asserts in tlie Latin edition (the phice is want- in^j^ in the Greek) that in the apparent peat-like ipizooties, horses which icere healthy were carefulbj separated from those which were diseased^ and their protection was sought hij bringing them iipon good pastures. Xo such regulation is to be found in any work of antiij[uity against the frequent pest outbreaks of disease among hu- man beings. We have now, in a very cursory numner, traced the history of veterinary medicine, or better, empiricism, to the tenth century, whicli may be said to begin the '" Stalihneisters," or master of the horse period. This period continued to the opening of the schools, and in all truth may be said to be still with us ; for every one well knows the taste among men occupying such positions to write ])rae- tical books '" on the care and treatment of the horse." While I would not deny more or less practical and empirical ability to men occupying these positions, I must em]iliatically enter an earnest pro- test against an American absurdity which leads otherwise intelligent citizens to assume that such persons know anything of disease, and which results in calling in to attend sick animals the first conven- ient stable-keeper, blacksmith, or cow-herd ; that because such men have gained a certain sort of practical knowledge with regard to the care of our domestic animals in health, it is justifiable to assume that they know anything of them in disease. Xo greater error ex- ists than this, and it has unfortunately extended itself into human practice, much to the cost of a suffering humanity. Experience is indeed valuable, but experience alone has proved a ledge upon which many a man has been wrecked. Times come when your practical man, your man of boasted experience, can do nothing but stand with fcjlded hands and wait. Such times come only too fre- quently to the man of still greater experience, and that backed up by a most elaborate education and reflective ability. AVithout edu- cation, without that systematic drilling and practice which can only be obtained in well-regulated schools and hospitals, experience is worse than nothing ; it results in nothing more than the most absurd guess-work. What idea can a man have of inflammatory processes in the lungs, kidneys, brain, or liver, M-ho scarcely knows the seat of those organs, much less anything of their anatomical construction ? In all truth, it is the most abject form of cruelty to give over a suf- fering dumb animal (alas I it is too often the case with human beings also) to the tortures or futile endeavors of one of these " experi- enced " quacks. Fortunate would it be for humanity, fortunate for our dumb animals as well, were disease and its treatment the simple 234 THE HISTORY OF VETERINARY MEDICINE. thing wliicli sucli actions on the part of those intrusted with their care would lead iis to assume that it was. On the contrary, the study of disease is one of the most difficult tasks which the human intellect has to cope with, and, while many men pass through life with the reputation of successful practitioners, still it is but the limited few who gain entrance to the " holy of holies," and acquire much inti- mate acquaintance with disease itself. That an occasional quack is rewarded by success is not to be wondered at, when we take into consideration the recuperative powers of Dame l^ature herself. !Noth- ing is more amusing, more saddening, than to hear self-important practitioners hoast of their cures. It is very, very hard, as many dis- tinguished men have admitted, and as every man who has devoted time to experiment in pathological and therapeutical research, but especially the latter, knows, to positively decide whether the im- provement which one sees in a given patient is due to the recupera- tive powers of ^Nature, to a weakening of the active properties of the cause of the disease, or to the action of drugs which have been offered. The best and most skillful practitioners are but handmaids., ser- vants, to Nature, and he is the best practitioner who most scrupu- lously holds to the rule, " hands off," and wnth religious regard aims to support the ever-active recuperative power, efforts, of the physio- logical functions. It is seldom given to the attendant upon organ- isms afflicted with inner diseases to effect radical cures / this boon is, however, occasionally awarded to the surgeon. Only the quack proclaims to have the radical panacea which can cure all and every- thing. But to return to our subject : The period which we are now considering in the history of vet- erinary medicine is marked by the appearance of several works of great historical importance. The first of these was the "Hippi- atrica" of Jordanus Rufus, " Marescallus Major" to the court of Frederick II of Sicily. The king is reported to have assisted on the work. Rufus seems to have known but little of the writings of his Greek and Roman predecessors, but, according to Haeser, was not unacquainted with several works of Arabian origin. His mind appears to have been remarkably free from the superstitions of his time. He describes quite a number of diseases, among them lami- nitis, vulgarly called founder, glanders, tetanus, etc. Schraeder * says of him : " He was born in Calabria, in the twelfth or thirteenth century, and was from a noble family, and, like many gentlemen of his position, busied himself with training * Loc. cit., p. 368. TOE HISTORY OF VETERINARY MEDICINE. 035 horses, and the treatment of their diseases. That lie must liavc been an important personage, and much esteemed by his patnjn, is attested by the circumstance that his names appear among the signers of the king's testament: ''Ego Jordanus maguus justitia ruis Rufus de Cahibria imperialis MarescaUus major interfui his et subscribi feci." (Frederick reigned from 1^12 to 1250 a. d.) Rufus's work, '' De Medifina Ecpiorum," appears to have been written with the advice and consent of the king, but it has been incorrectl}' asserted that the latter himself wrote it. It appears, from Rufus's own words, that the king had already died at the time of its publication, which accordingly must have taken place subsequent to 1250. It was written in Latin, but at an early date was honored with transla- tions into Italian, and in ISIS violin, professor in Padua, gave out a Latii\ edition. None of the ancient Latin works upon this subject afford more pleasure to the reader than this of Ruffus's. From it one can easily perceive that he was a person of considerable expe- rience, far exceeding any of his successors in ability for a period of nearly four hundred years. We do not find in his writings any of the superstitious fables or astrological nonsense which encumbered the works of his predecessors; he was an earnest student of Nature, and erave his conclusions with earnestness and directness. It is certain that he knew little of Yegctius, or of the collected writings of Greek authors ; at least, he made but little use of them. Many of his di- rections are not without value even in our day. Many names which he gave to diseases have been adopted into other languages. Hazard possessed several manuscripts, and especially a French translation of his writings. The contents of one of these manuscripts on vellum, from the fourteenth century, is given as follows : 1. The Creation and Nativity of the Horse. 2. His Capture and Training. 3. The Care and Treatment. -4. The Recognition of the Parts of the Body. 5. The Diseases. 6. The Medicines and Remedies. The invention of printing gave a great im])etus to the publica- tion of works of all kinds — to a degree, in fact, which we of this day and generation can scarcely appreciate. In this regard the pub- lication of medical works kept even pace with those of theology and other bninches of learning. In our own field of study there ap- peared a work of rare value ; one, indeed, which marks a turning- point in the development of veterinary medicine. Up to this time there had been no book on the diseases of animals since the days of Aristotle which endeavored to enter at all into the study of their anatomy based on special dissections. This ground was first broken by an Italian work entitled " Dell' Anatomia et dell' Infirmita del 236 THE HISTORY OF VETERINARY MEDICINE. Cavallo," di Carlo Ruini, senator of Bologna, 1598. This work contains numerous illustrations, finely executed, when we take into consideration the period and the condition of equine anatomy. It remained unequaled for nearly two hundred years, when its place was in part taken by the really magnificent '* Cours d'Hippiatrique " of Lafosse,^Z5, Paris, 1T72. Carlo Ruini* was born and died in the sixteenth century, at Bologna, Italy, the exact date being unknown. His grandfather was a professor of note at the university of that place, lecturing upon jurisprudence. Kuini also studied the same subject, and, as stated on the title-page of this book, became senator in his na- tive city. But little is known of his life, but in the preface of the book in question it is said that from early youth he displayed a great fondness for horses. The original edition of this work ap- peared in 1598, and the printing and paper are marvels of perfec- tion. Uffenbach gave out a German translation, and several from French sources soon followed. The book served as a fountain from which subsequent compilers drew much information, using also the illustrations, which, however, frequently lost much credit in the copies made of them. The first part of the book treats of the anat- omy of the horse, and the numerous illustrations testify to the dili- gence of the author in dissections. The second part treats of the diseases of that animal, and is based in no inconsiderable degree upon Euffus and other authors. As little as the authorship is in general to be questioned, yet it is very doubtful if the " Anato- mia del Cavallo " is from Ruini's hand. " I harbored this doubt," says Schraeder, " very early in my study of this book, and the more I have reflected upon it the more have I become confirmed in my doubts. It is my opinion that some young doctor had at his own instigation, or perhaps incited by Ruini, studied the anatomy of the horse, and drew the illustrations, and had them engraved upon cop- per, which could not be done save at considerable expense, which the wealth of Ruini made possible." Ercolani, one of the most learned veterinarians of Italy, and celebrated for his researches into historical veterinary literature, questions the above assertion, and gives full credit to Ruini. I have casually mentioned the brilliant contribution to veterinary literature, the " Cours d'Hippiatrique" of Lafosse^^^. While Rui- ni's work was the first illustrated book of any account which had until then appeared, that of Lafosse was the first book with colored plates which appeared upon equine anatomy. The work is divided * Schraeder-Hering, loc. cil., p. 369. THE HISTORY OF VETERINARY MEDICIN'E. 037 into three parts, ami is embellished with a fine copjier print of the author. The first part treats of the anatomy of the horse ; the sec- ond, of its diseases and their treatment ; the third, of horseshoeing. It is impossible to doubt the influence of Ruini, when one thought- fully compares the plates and the arrangements of both these works. At this period two men, father and son, occupied most prominent positions among the veterinarians of France. I must beg leave to nourish the opinion, heretical as it may seem, that it was an unfor- tunate thing for France, unfortunate for the development of veteri- nary science, not art, that the first veterinary schools established at Lyons and Alfort, France, were not established under the direc- tion of the younger Lafosse, rather than under that of his great rival, Bourgelat. Bourgelat was a horseman, eminently practical / hence we see horseshoeing and all practical routine assuming a jilace in French veterinary medicine, at the cost of the scientific in- vestigating spirit, which would not have been the case had the more scientific and original but not the less practical Lafosse been the guiding star. I wish to call particular attention to this opinion, for here in America we are in great danger of losing the true union of science and practice, before the great practical common sense that our people are so fond of assuming to themselves. "We have not yet learned, at least so far as the study and development of medicine is concerned, that experience is a dear task-master. I would not have it inferred that I would neglect the practical — I am too much of an American for that — but true practice must ever stand upon the results of scientific research ; upon an empiricism based upon some- thing else than the trrtditions and errors of our forefathers ; the things which have been, but which have never at the same time been subjected to the skeptical crucible of the experimental, scien- tific researcher. As the two Lafosscs. especially the son, exerted such an influ- ence on the development of veterinary medicine, a short notice of their lives can not be out of place here. "■ Etienne Guillaume Lafosse,* the father, was born in Paris, and died there January 24, 1765, Little that is authentic is known with reference to his life — he appears to have been lost sight of be- hind the greater renown of his glorious son. Yet it was to him that the son owed his careful education in the scientific and practical ele- ments of his profession. The father had, however, given us some idea of his ability by his investigations on the seat of glanders, published in 1779, in a treatise entitled " Le veritable siege de la * Schracder-IIcring, loc. eit.y p. 234. 238 THE HISTORY OF VETERINARY MEDICINE. morve (glanders) et les moyens d' j remedier " ; in 1750 he gave to the Academy a brochure upon lycoperdon as a haemostatic, anti- bleeding medicine ; and in ITSi published a work on horseshoeing. Other writings upon horseshoeing and ^^ractice followed, several of which, as also the above, were honored with translations into other languages." " Pliil. Etienne Lafosse, the son, was born at Montaterre, near Paris, and it is said died at Yilleneuve, upon the Yonne, June, 1820. He was the eldest son of the former Lafosse, and at thirteen years of age decided to follow the calling which had been so honorably followed by his father and grandfather." (It should be mentioned here that this family has been one of the most noted among those which have given worthy veterinarians to France, and that it is not without honorable representatives at the present day.) "At the conclusion of his school-days, his father required him to serve for a time in his stables, where he acquired proficiency in the handling and care of horses ; he then went into the forge for two years, and at the same time devoted himself to the study of human anatomy. He also received instruction in fencing, drawing, and music. Then followed practical experience, gained by accompanying his father upon professional visits, at the same time continuing the study of equine anatomy. By visiting knacker establishments, and making autopsies, he constantly enriched his collection of specimens. At eighteen years of age he received an appointment to lecture upon equine anatomy to the members of the light cavalry stationed at Yersailles. He also did the same at the house of his father for the students in the forge. In 1758 we find him stationed as army- veterinarian, and accompanying the army in two campaigns into Germany during the Seven Years' War. On his return he studied medicine at Paris. In 1767 he built an amphitheatre, and gave therein free lectures and demonstrations upon equine anatomy ; these lectures enjoyed great and deserved notoriety, but in 1770 he gave them up in order to bring to completion his great work, " Cours d'Hippiatrique " ; the same cost Lafosse seventy thousand livres, and gave him an immortal reputation, especially in foreign countries. He did not, however, enjoy the same good fortune among his own people, for, not only in this work, but also in his " Dictionnaire d'Hippiatrique," 17Y5, he displayed a most active opposition to the schools at Lyons and Alfort, or rather, against their founder, Bour- gelat. He nourished a great ambition to become a teacher, or even director, at one of these schools, but his severe polemics seem to have completely shut him off from the desired end. Bourgelat was THE HISTORY OF VKTEKIXAUY MEDICINE. 239 a far more politic character, and stood in lii^li favor witli tlie min- istry, and his scholars gave him such ardent support that the severe critique of his opponent passed him liarmlessly by. Tlie disappointment to his ambition, in unison with sufferinfi^s caused by a stone in the bhidder, made him sell his house in Paris and remove to Russia, where he remained from 1777 to 1781. It is not definitely known what positions he occupied while tliere. But in no case could he find himself at home in the despotism ruling in Russia, and soon returned to Paris, where he rapidly assumed a position at court as veterinarian, and was also appointed to a simi- lar position in the carabiniers and gendarmes. From his discon- tent with the government, it is not to be wondered at that we find him taking an active part in the acts of the Revolutit)n, which soon followed : he was present at the storming of the Invalides and Bastile ; became a member of the armed commission, division com- mander, and municipal officer of Paris. But we do not find his revolutionary ideas confined to politics alone ; his hatred against the existing veterinary institutions and Bourgelat again found full vent, and he easily saw reasons for the suppression of both, and the rc- mt)val of the schools to Paris; among other things, he accused the existing powers of supporting a costly and unnecessary menagerie, besides unnecessary instruments, and of accumulating a debt, in the years between 17S2 and 1785, of thirty thousand livres. La- fosse was a hippologist par excelhnce^ and this exclusive devotion to the horse wius used successful!}' in the arguments against his polemic attacks on the existing institutions. Although the authori- ties took so little notice of his polemics, yet Lafosse did not fail entirely of public appreciation, for we find him appointed to sev- eral important positions as inspector and examiner in connection with the army. In all these he displayed his usual activity. On the 29th of July, 1794, he narrowly escaped death upon the scaf- fold. He then left Paris, occasionally revisiting it, however, and retired to the country, where he busied himself in scientific studies, occasionally appearing before the public In 17i>7 he read a pajier before the National Institute, entitled " Memoire sur une maladie epizooticpie vaccinique dans le Canton de Bray, qui a regni pendant Tet^ de Tan V, jusqu'd la fin de vend^miairc an VI." Other i)apei-s followed this of no less importance. In 179r» he was elected asso- ciate member of the Institute, but, notwithstanding earnest endeavor on his part and that of his friends, he diil not succeed in becoming virtually a member. In 1819 he again vented his hatred against the schools in a writing entitled " Nouvellc Theorie pratique d'equi- 240 THE HISTORY OF VETERINARY MEDICINE. tation." He possessed bis great activities until tlie close of liis days, and frequently complained of the unthankfulness of his fatherland — an ingratitude which, notwithstanding his failures, is still dis- creditable to his countrymen, for if Bourgelat deserves a monument to his memory for what he did for France, Lafosse no less deserves one for his services to the world at large, for none of the literary work of Bourgelat equals that which has given a world-wide repu- tation to the greater Lafosse. Other books, which have acquired at least a certain historical importance, but which are of but little practical value, with a few exceptions, at the present day, were the "Parfait Marechal" of Solleysel, 1664, which was honored with translations into several for- eign languages ; the writings of Saunier, mostly based upon books which had preceded him; Diaz, in Spain, Yon Zind, Newcastle, Winter von Adler's Flugel ; Marx Fugger, on Breeding ; the " Foure Chiefest Offices of Horsemanship, whereto are added, Diverse Medi- cines not Heretofore Mentioned," by Thomas Blundeville, of New- ton Flotman, in Norfolk, England : London, 1609. (Blundeville is, I believe, the originator of the term " Poll-Evil ") ; the " Hippono- mia, or Vineyard of Horsemanship," Baret, 1661 ; " Master Peese, Containing all the Knowledge Belonging to the Smith, Farrier, Horse-Leech," etc. ; the " Complete Horseman," of William Hope, 1696; "The Farriers New Guide," by Gibson, 1719; Snape's "Anatomy of the Horse," 1751 ; and a very remarkable book from Stubbs, on the " Anatomy of the Horse," 1766. During this long period the Continent of Europe and Britain had been frequently overrun with animal plagues. Interesting as a condensed history of these invasions would be, it is not my purpose to enter upon it here, but gladly refer those who care to pursue this subject to the very elaborate work of Mr. George Fleming, entitled "Ani- mal Plagues," where it is treated in detail. Of these plagues, the rinderpest and pleuro-pneumonia of cattle caused the most se- rious devastations, and I shall presently have occasion to quote largely from the above-mentioned "Animal Plagues," from the writings of three men who played an important part in their sup- pression, but better still, in instructing the people and governments in the means of combating them ; instruction which is as applicable to our day as it was when written, over one hundred years ago. It is scarcely possible for the people in this country to form any conception of the devastation and misery caused by these plagues in Europe during the eighteenth century ; and not only these, but plagues unknown to us, carried death and misery among the pec- THE HISTORY OF VETERIXARV MnDiriyE. 241 pie themselves. AVai-s on wai-s, •\vitli all their accompanying evils, lunl impoverished hoth the governments and })eople. Epidemic on epidemic had almost broken all the himling ties of kindred and affec- tion. Plague on plague had driven people to the last verge of hope for sustenance and wealth, by robbing them of their animals, more) especially cattle. " It has been computed that from 1711 to 1714 no; fewer than one million five hundred thousand cattle died in Europe' from cattle-plague." A competent authority tells us that between' 1711) and 1709 "not less than two hundred millions of cattle were! destroyed by rinderpest alone." * These figures might easily be aufirmented to a deffree almost bevond human concei>tion. In our own day millions of dollars' worth of valuable animal property is yearly swept away by these ravaging destroyers. Ignorance and su- perstition prevailed among the people. Where should they look for aid ? The doctors were powerless. The veterinary empiricism of the day sank as an imbecile before the furious storm. The Church cried that the Almighty was angry, and punishing the world for its sins. " Come to me — I alone can save you ! " said an equally iinbecile priesthood. The people went ! Instead of help, they found husks. In spite of the invocations of anointed bishops, in spite of the sacred and all-preserving charms which the Church affirmed were possessed by the consecrated oils, or by the burning cross, or heated key of the all-holy saints, Martin and Angelo, in spite of Inquisitional tor- tures inflicted upon an already suffering animal world by these bar- barians of the Church, in spite of all the powers of man, on went the ravaging pests, carrying death and misery in their path. Empirical curers, then as now, were to be had on all sides, but their medicines were as empty of effect as their brains were of knowledge. The so-called veterinary profession was as powerless as the mighty Church ; priestly imbecile and veterinary quack joined hands in producing nothing. "Woe, woe was on every side ! Hope alone was all that poor humanity had to depend upon. Men felt that they were indeed deserted by (rod, and that the Father of the heavens was no more mindful of his children. But this was only so in ajipearance. AVe have arrived at the latter part of the eighteenth century, and found — what? That no veterinary science existed; that no veterinarians had added anything of much value, other than a few- things of practical import, to human knowledge. But the medical profession had not been idle. "While Luther was battling, as a son of Mars, for the freedom of the human intellect from the trammels • " AniiDal Plagues." 16 242 THE HISTORY OF VETERIXARY MEDICINE. of an imbecile snperstition, and in part demoralized priesthood, Truth was not without her able representatives in many fields of science. Yesalius was following in the path of Luther, and bring- ing things which had been, until then, hidden in an impenetrable darkness, to the light of the world ; the human body was, for the first time, subjected to the analytical power of the human intellect, and the anatomist's scalpel was daily revealing truths before which the superstitions and myths of thousands of years disappeared as the mists before the morning sun. The Church shouted her anathemas, but in vain. In spite of curse, hatred, persecution, and calumny, on went the bark of truth, emphatically testifying to the wisdom of the words of the Eastern sage, " Truth alone is the mightiest of all things, and will live forever." Yesalius was a reformer of the truest type ; but to progress, other elements are also necessary. They seek to pull down, not to build up ; they serve to tear away the cobwebs, which, as superstitions, prevent the new light from gaining entrance into dark corners. The sun of revolution in medicine found its representative in Paracelsus, a wonderful mixture of superstition and common sense himself, but nevertheless a man who did no small work in preparing the way for the truth to enter men's minds. On went the march of investigation. " More ! more ! " was the cry of a hungering humanity ; and the answer came in the great and im- mortal Harvey's unlocking the keys to an unknown fountain, and teaching men how the flowing blood was forced through their or- ganisms. England then denied her child, to honor him in future generations as among the " anointed " of the sons of men. Tlie great Hunter laid the foundation of a new science, and made the world a debtor, by laying the foundation of the first museum for pathological anatomy. Boerhaave was teaching a mighty class of scholars, whose fame was to make his great name still more famous. Yan Zwieten laid the foundation of the first hospital in Yienna. Glisson started the doctrine of the irritability of the tissues, which found its more complete elucidation at the hands of Haller, im- mortal physiologist, poet, philosopher, statesman, and naturalist. Harvey and Haller must be looked upon as the fathers of modern physiology. It is not an uninteresting fact that Harvey freed the world of errors which had been held ever since its beginning, in the same year (1620) that our "Pilgrim fathers" broke the ground in favor of human rights on the "Western Continent. Haller, Lancisi, Ramazzini, Bates, and others, did the work that an incompetent vet- erinary profession could not do, by describing the animal plagues, especiaUy pleuro-pneumonia and cattle-plague. Xot only did these THE HISTORY OF VETKRI.VARY MEDICLNE. 243 men describe, tliey also made most careful observations as to the manner in which these pests extended, and elucidated means of prevention entirely applicable to our day, and which had we, in this country, sense enough to study and follow, would save us untold millions in the future. So true are the descriptions given by these men, so far-seeing the instructions they give for prevention, that I feel myself impelled to give them here. Speaking of the animal pest which devastated Europe in the eighteenth century, Fleming says : " The cattle-plague — rinderpest — continued its ravages in all the countries named in the preceding year (1712). In Knssia, it had enlarged its boundaries. In Ger- many, it was reported at various places. It was still spreading in Switzerland ; but in Holland its violence was excessive; it was said tluit there alone, between 1713 and 1723, it destroyed two hundred thousand cattle. In Italy it was steadily marching on, and causing havoc on all sides. In Naples, Calabria, and liomagna, its advances were causing the utmost apprehension and fear. The learned doc- tor and j)hysician of Pojie Clement XI, Giovanni Lancisi, was sent to investigate the nature and prescribe measures for the suppression of the pest. To the ability of this man, while obeying his instruc- tions, we are much indebted for an accurate description of the symp- toms and posi-mortciii appearances of the malady, as manifested in that part of the Roman dominions. His report is as follows : ' In the middle of the summer of 1713 there was a rumor at Rome that a large number of infected oxen from districts on the Mediterranean were being driven from the market of Frusinoso to us ; wherefore it was wisely decreed that no markets should be held, or any cattle be driven into the place. But merchants introduced oxen into the city S'Crithj h>j hij-icays^ hecause their Iwpes of selling thnn publicly hadhein frustrated ; and these ^ heiny driven ahout in all directions^ and l>€coming mixed with our hitherto healthy stock, spread ahroad the disease. For, ichen foreign merchants had doubtful or suspi- cious cattle, which they could not sell in their own country, they brought them to Home surreptitiously, and sold them for less tfian the usual price."* " * This pliilosopher and far-seeing jiatriot gives us such a high opinion of his wisdom and truthfulness in his work on this plague, that we nuist quote more largely from his report, lie had no doubt whatever as to its being an inijiorted disease. As (piic-kly as pos- sible, when its presence was discovered, all traffic in cattle was to be prohibited, and the law enforced with the utmost rigor in the case of * Fleming, "History of .\nimal Plagues," p. 198. 244 THE HISTORY OF VETERIXART MEDICIXE. those who moved cattle about. But the disease was still raging ; " as a neglected spark at first, it had at length set Italy in a blaze," and was extending everywhere. Lancisi described the disease, dwelt on its terrific character and the hopelessness of medical treatment, and then recommended what he deemed the wisest course. " I advised that every diseased animal should be killed ; for, I maintained that, should they be left to a slow death, the cost of medicines, veterinary surgeons, attendants, and other means, would be very great, and not only this, but their very presence would assist in the diffusion of the contagion. The Sacred College, however, ordained that this meas- ure was too severe, and that remedies should be tried ; and, in tnith, they were greatly influenced in this decision by the number of people who pretended that they had infallible cures for the affection. But the fact is," added Lancisi, •' that in the cattle, as in the human plague, not every one who takes the disease dies of it. Some re- cover, thanks to Nature, rather than to the remedies which are re- sorted to." The attempts to cure the disease only resulted in failure, and its indefinite extension. Edicts were issued, forbidding the bringing of cattle from the Cam23agna into the district of Home, under the penalty of death to a layman, and of the galleys for life to an ecclesiastic. The sale of hides was interdicted, and the flesh, horns, and fat of the animals were ordered to be buried in deep pits and covered with quicklime. Measures were taken to prevent the sale of diseased meats. Inspectors were appointed to visit the mar- kets, and only those pieces of flesh which were stamped with a hot iron by the inspector were allowed to be sold. Skinning the dead carcasses was forbidden, as it might lead to the further extension of the disease. The severity of the edicts was complained of ; " but it is a fact," he adds, " that here^ where the laws were strictly enforced, the plague was arrested much sooner than in other parts of Italy." The various edicts issued by the Sacred College are given at length by Lancisi. He thinks " they will be of great service to pos- terity if a similar misfortune should ever again happen — which may Heaven avert ! " Posterity has heedlessly passed them by many and many times, and has consequently paid the penalties of its neglect. The last chapter of this invaluable work sums up his admirable reflections upon this disease : " The steps which a wise government should instantly take, whenever the pestilence may again appear upon our borders, are these : all roads and by-paths should be care- fully guarded, so that no ox or dog be allowed to enter the coimtry. Any animal so entering should be forthwith destroyed and buried. THE HISTORY OF VETERINARY MEDICINE. 245 Should the pestilence, however, gain admission, the separation of the sick from the healthy must be enforced by decree. Luhed^ in my oj^inioHj by far the safcd course Is instantly to destroy tlie ani- mal with the poh'-axe^ so that no infected hlood may escape on the ground ; for, in attempting to cure the diseased animal, the veteri- nary surgeon may convey the disease to healthy animals. The healthy cattle nmst be removed from their former pastures, which must be roirarded as contaminated. The diseased oxen should be kept in stables, to which no one is admitted except the veterinary surgeon or the herdsman. The fountains and vessels used by the animals should be frequently cleaned with quicklime. The clothes of the shepherds should also be fumigated. The dead carcasses, from which not one hair is to be removed, must be buried in deep pits ; any saliva or secretions which may drop from them on the way to the pit are to be carefully removed. If any cows are infected, their milk is instantly to be thrown into a hole in the ground ; and the severest punishment should be inflicted on those who disobey this order. The passage of all rustics and dogs should be forbidden." That Lancisi's teachings liave not been entirely neglected is shown by the following letter, written to Mr. Fleming while I was a student in Germany:* My dear Sir : I have just read your very judicious and reason- able letter in the "Times," on the ''Cattle-Plague," and being here at Berlin, the headijuarters of this outbreak, it may not be uninter- esting to you to hear from me as to what I have seen. The whole state, we will say, is divided into thirty-six depart- ments, and these again are subdivided into districts ; over each of these districts is an official veterinarian, known as the " Kreis- Thierarzt," or district veterinary surgeon, and the same arrange- ment is carried out over the entire Empire of Germany. All these men are selected for their ability, and especially for their knowledge of contagious animal diseases ; in the smaller towns the " Kreis- Tbierarzt" is one of the men of the town, and has for so<'iety those who are considered the leading men of the place. The " Departc- ments-Thierarzt" is a much greater character; he is an unusually well-educated person, who nmst be thoroughly posted in regard to the laws of the empire relative to his profession and duties, and is responsible to the local state authorities, as well as to the ministry, for the faithful performance of his duties ; the " Kreis-Thieriir/.te " are responsible to those of the departments. These officers all re- ceive salaries from the state, varying from fifty to four hundred • Published ia the " Veterinary Journal," 1879. 246 THE HISTORY OF VETERINARY MEDICIXE. pounds per year, and also are permitted to receive fees for their official attendance in addition to their regular fees. They are fur- ther favored in their practice bj their official positions, it being a guarantee to the public of their competencv. Prussia does much to encourage graduated students to continue their studies. This -win- ter some thirty men, from twenty-five to forty years of age, are re- ceiving about forty pounds each from the Government to pay their expenses in Berlin, while they are attending lectures and studying ; and at the time I write they are being examined for higher positions. Every year a new set arrives ; so you will understand that our sci- ence is properly encouraged on the Continent, and a man has some incentive to work. In Prussia, to every 4*75 square miles (geo- graphical) there is a veterinary surgeon, and to his care are confided 1,544 horses, 4,592 cattle, 14,221 sheep, 2,192 hogs ; and there are (these figures apply to 1875) 1,290 veterinary practitioners. This has no reference to the number of official veterinarians. These few remarks will serve as an introduction to the remainder of my letter. Early in January there was an unusual excitement to be noticed around our school ; messengers were to be seen rapidly passing between the offices of the Minister of Agriculture and the school officials. It soon transpired that " der Teufel's los," as it was expressed to me, or, in other words, the " rinderpest " was in Ham- burg. It took but a short time to arrange mattei*s. Professor Miil- ler, whom you know as an anatomist, and a great authoi-ity upon this scourge, was dispatched to Hamburg with a high government officer. Another great expert was sent to the Russian frontier ; every department veterinary officer was notified by telegraph, and in less than twelve hours an embargo was placed upon every head of horned cattle in Germany. If I mistake not, your Government was officially informed of the sailing of the Castor with infected cattle from Hamburg, in sufficient time to have stopped her before reaching London. She should have been stopped some distance from that port, her hatches battened down, and the vessel and cargo towed somewhere, sunk, and paid for by the Government. If this was in reality the first infected cargo, then England would perhaps have been preserved from a serious loss ; the future can alone prove what the loss may be. To return to the outbreak in Germany. The Berlin and all other markets were most vigilantly watched, and no cattle or other animals were allowed to be removed from them alive for slaughter in the city. (All cattle moved at any time from the markets in Berlin are moved only in large cattle-wagons ; the same is true of THE HISTORY OF VETEIilN'AIiY MEDICINE. 247 every other marketable animal, e\i'ej)t horses. Glanilered horses and suspected horses are invariably moved in wagons, either to the school for inspection, or to the knackers, to be immediately killed.) All cattle that had to be removed were tirst rigidly inspected, and then conveyed in wagons, and put directly upon the cars; and bo it was all over the country. Alluding to your remarks in the " Times," on the futility of inspection when the disease is latent, a fine in- stance occurred here, which our mutual friend Professor Dieck- erhoff unraveled with his customary ability. He was called to "\Vest})halia, it being rej^ortcd that a cow there was suspiciously dis- eased. On his arrival the cow in question had been killed, or had died, but her illness was said not to have been rinderpest. It was, huwever, reported that another cow was sick, and this animal was immediately placed under lock and seal, and the case proved to be one of rinderpest. As the story is interesting, it may be useful to relate it in full : This cow had been bought in Berlin by a butcher, who was a Jew ; it was there inspected and passed, put on the cars with others, and taken to the town, the name of which I have forgot- ten. The other cattle were at once killed ; but the butcher having a child suddenly die, the remaining cow was sent to a friend for a day or two, for him to keep, and during the interval the disease liad time to develop. Professor Dieckerhoff traced the whole affair from beginning to end ; the cow was killed, and rinderpest proved to be present. If this cow had been killed with the others, the disease might have been spread without the real cause ever becoming ap- parent, or brought to light. I have purposely refrained from saying anything about the action of the authorities in these special cases ; in the investigation of some othera it Avas my good fortune to be present. Early one morning about two weeks since, Professor Dieckerhoff sent for me ; it was just daylight, and, witli him and four other students, we started for a village, about thirteen miles from Berlin, where a cow was reported to be sick. I should state that the Government keeps a very nice " turn-out" and four horses for this purpose, and Professor DieckerhofF has this clinic (at pres- ent he has charge of the school hospitals) — taking four students each time with him, your humble servant going when anything interest- ing is likely to turn up. "We arrived in about two hours, the roads being heavy ; we met the local officers and proceeded to the sus- pected farm-house, but did not enter until we had proved our right to do so ; the house being guarded, and not a person allowed to leave or enter the premises, but to speak or pass things in or out through a window. I omitted to state that Professor Dieckerhoff 248 THE HISTORY OF VETERINARY MEDICINE. and the renowned Hertwig had been there the previous day, and it had been decided to allow another to pass, in order that the symp- toms should become sufficiently developed to prove the existence of the disease, the place being well guarded. During the night a trench had been dug some forty feet long and some fourteen deep in an entirely isolated wood, which we could reach without crossing a public way. We removed the cow, made a necroscopical exami- nation, proved our case ; her nine companions were brought after her to the same place, with their chains and stable-utensils : the cows were then shot, after the decision of the proper officers had been given, and they with the utensils were at once buried — a military guard over the place, another about the farm from which they were taken, and also on the streets leading to the village ; the inmates of this particular place being confined strictly to their own limits for a time prescribed by law. JSTo cattle or farm animals were allowed in the streets, and only persons permitted there with teams who had received sanction from the authorities. All those who had had to do with the infected cattle were most effectually disinfected ; while those that buried them had no cattle themselves, and were not al- lowed to go near any within the lawful time. I heard an officer say that the pastor of the village must be carefully watched : that these gentry were unfortunately apt to be spreaders of contagium, the guards of ter allowing them to pass as favored persons, and then they innocently, of course, must go to the stable, see things, and after- ward go to another neighbor to mention the loss of neighbor So- and-so. This has often been the case, I am told, in Germany. The manure, the stall, and all things about the stable, are carefully cleansed and disinfected under the supervision of veterinary officials. I was surprised to see numerous military about the fields and streets, ap- parently with no purpose, yet carrying rifles ; their duty, it seems, was to shoot every dog, cat, or valiant chanticleer, which they might see straying abroad or leaving the proper quarters. Doubtless the Prussian course may seem tyrannical and severe — all the cattle are killed, not only the diseased, but all belonging to the infested farm or stable — but the law is, to my mind, essentially democratic ; it is for the good of the whole, and the cattle killed and utensils de- stroyed are paid for by the state at market prices. The remarks of TIaller upon certain contagious animal diseases, rnore especially the pleuro-pneumonia of cattle, which is of such vital interest to the people of this country at present, and which bids fair to become a most serious economical problem to American statesmen, certainly more than warrants their introduction here. It TUE HISTORY OF VETEIUXARY MEDICINE. 049 is not, liowever, iiia])propriate to the siil)jec't of this book to gwo a short sketch of the life of a man uho has wiekled such a mighty intellectnal iutiuence in the world's progress. '' Albert von Ilaller * was born at Bern, Switzerland, in 1708, and in early youth demonstrated a systematic spirit and a strong scien- tific tendency. lie began to make for himself a private dictionary as soon as he was able to write, in which he entered all words hith- erto unknown to him, with their meanings, lie also made a dic- tionary of a similar character as soon as he began the study of for- eign languages, and when he began the study of history he followed the same course. He often said that in his later years he found valuable information in these works of his youthful days. AVhen ten years old he had already shown his taste for poetry by writing ludicrous verses about his teachei's, his poetic talent at this time having a special bent to satire, which he, however, entirely gave up in later years. In l~'2'-\ when he was fifteen years old, he went to the Univei*sity of Tubingen, to study medicine under Duvernoi and Camerarius. In the ne.xt year he wrote a polemic against an ana- tomical assertion of Professor Coshwitz at Ilalle. He did not re- main long at Tubingen, ;is he, with other students, had made a shepherd so drunk with high-wine (Branntwein) that the latter lost his life. In 172.') he removed to Lcyden, to study under the guid- ance of the immortal Boerhaave. At eighteen years of age he ac- quired his degree of doctor of medicine, visited England and France, but had to flee from Paris, because it was found that he had made dissections of human bodies at his residence. From Paris he went to Basel and studied mathematics under Bernoulli ; but in 1729 he returned to the place of his nativity, Bern, in order to practice his profession ; at the same time he studied botany with great earnest- ness. In 1734 he became director of the hospitals of his city, and also had an amphitlieatre built in which he gave anatomical lectures. Most of his poems were written at this time. In 1735 he had con- trol of the City Library, which he himself used with the greatest diligence. In 1730 he was called to Gottingen as Professor of Anat- omy, Chemistry, and Botany ; he also explained the ' Institutions ' of his master, Boerhaave, which he himself })ublished with commentaries in 1730. At this period he still busied himself with botany, and pub- lished several works of classical importance upon the subject ; he also wrote a large number of important anatomiciil papers, besides publishing an atlas of anatomy. But it is for his contributions to physiology that Ilaller is as much noted as for any other of his mani- * "Geschichte d. Mcdicin," Wundcrlich, Stuttgart, 1859, 250 THE HISTORY OF VETERINARY MEDICINE. fold accomplishments. His Urst appearance in this branch of sci- ence was a polemical work on respiration in 1727. He demonstrated that there was no air between the pleura costalis and lungs, against the contrary assertions of Professor Hamberger. Haller's fame, and with it that of the Gottingen University, increased each year ; he laid the foundation of the Gottingen Scientific Society, and a periodical, which is still in existence, devoted to science. After sev- enteen years of unceasing activity his health broke down, and he was obliged to return to Bern in 1753, where he took an active in- terest and part in the government, and published numerous works upon botany, anatomy, surgery, the practice of medicine — all of them of classical importance. During the last years of his life he scarcely left his library — sleeping, eating, working, and receiving his friends and visitors there. His wife, children, pupils, and friends were all kept busy aiding this wonderfully gifted man in his work ; only in this way was it possible for a human being to give to the world the almost incredible amount of literary work which he did. Haller died, beloved and respected of all, at the place of his birth, on the 12th of December, 1777." In 1877 his native city fitly celebrated the one hundredth anniversary of the death of this her greatest son, whose name and fame will be held immortal so long as memory lasts and mankind continues to reverence the noblest among the children of the world, who, though dead in form, still live that immortality which is given but to the selected few. I have previously mentioned that among the most important con- tributions to veterinary literature in the eighteenth century was a writing by Haller upon an epizootic disease of the cattle of Switzer- land, an edition of which appeared at Bern in 1773, entitled " Me- moire sur la Contagion parmi le Betail." " In this year (174:5) * the immortal Haller published his inves- tigations into the nature of an epizootic which had several times been observed in Switzerland. The great physician supposed it was the ' cattle-plague,' but no one can read his description of this Swiss malady without surmising that it was a different disease, in all probability the bovine contagious pleuro-pneumonia. Such an authority needs no apology for being quoted here, especially as his preventive measures are worthy of notice, and would probably have saved this country a great loss had they been adopted in recent years : " 1. The first thing necessary is to determine the nature of the disease. This knowledge is not easily acquired, for frequently it * Fleming, loc. cit., p. 446. THE UlL>TORY OF VETEItlNARY MEDICINE. "51 does not niaiiifest itself by any perceptible pymptotiis for a lonlague^ the smallpox, and other contagious diseases. "5. A long experience has taught us tliat remedies are useless against the contagion. The beginning of the disease is nearly im- perceptible, and when the symptoms arc manifested the cure has become almost impossible. The use of remedies is otherwise dan- gerous, for the infection is really communicated by the breath and exhalations. We have a proof of this in the foul smell attached to the clothes of people who look after the diseased beasts. "We can not hope to cure in a day a disease of so serious a character; and thus the diseased creature, which lives in the same stable with other cattle, and feeds and drinks with them, may infect them during the time we are unsuccessfully attempting to cure it. These same exhalations may also lodge in the clothes of those who go 254 THE HISTORY OF VETERINARY MEDICINE. about tliem, and thus become dangerous to the animals yet in health. '• We can not, then, hope for any good from remedies. For more than two thousand years an infinite number of the most learned men have given their constant attention to observing the effects of medicines on mankind. We know well enough the value of sim- ples, the properties which they have of stimulating or evacuating, and their dose. But we have not nearly the same knowledge to guide us when we deal with animals : few talented persons have observed their diseases ; the art of curing them has been left to men of low condition, who have no knowledge of the anatomy of the lower creatures, and who have not informed themselves by the study of nature or of good authors. The cattle-doctors invariably fol- low the same routine traced out by the ancient veterinarians, and their science (art) consists of divers receipts which they have found among the papers of their predecessors. " The structure of the stomachs of cattle is very different from that of man; in general, the envelopes of their nerves are much thicker, the sensations less active, the pulse less frequent, the arteries more hard, the heart less irritable. All these peculiarities change the effect of remedies in animals, in a way quite different to man ; and it is only within a few years that convincing proof has been afforded of the differences between the effect which a given remedy has on man and the animals. The saffron of metals is a violent emetic for man ; in the horse it only increases the transpiration ; a dose of glass of antimony, which produces violent vomiting in man- kind, simply purges the horse ; no poison will make a horse or cow vomit. Because the effects of medicines, therefore, on the lower animals are so little known ; because scarcely any one has observed closely enough the diseases of cattle, or given definite rules for the exhibition of the proper remedies ; because the use of remedies can only tend to spread the contagion — for all these reasons it is pru- dent to abstain from a dangerous tentative which promises but lit- tle, and which may have the worst effects ; it is infinitely preferable to oppose the disease by means which are more certain and com- mendable. '' 6. We hegin ly disabusing the pxiblic of the idea that the pneii- monia {la pidmonie) is not a contagious disease. This outrageous idea even comes from some savants. There are those, too, who rob the plague of its contagious power. I do not pretend to say that the skin of an infected beast preserves its contagious properties for a long time after death ; experiments upon this matter, which deserve THE HISTORY 01" VETEUIXAllV MEDICINE. 255 attention, have been made in France. It is necessary, nevertheless, to remember that the j)hi<:jiie attaches itself by preference to the wool and the hair of animals, that it may be transported b}' these materials, ami that they will spread the contagion to other towns and countries free from the contagion. It is, then, possible that the poisonous exhalations of the diseased beast attach themselves to the hairs of animals which go near it. It is at least certain, in our country, that as often as the disease is manifested among cattle, and when it has been traced to its source, it has been found that a beast which has been purchased in the market of some suspected place, or which had been brought from some suspected locality, has carried the contagion with it to a new center. Sometimes, also, the cattle of our regions have been pastured with those of a neighboring in- fected country. It is very probable that at other times the air of the infected mountains has spread the dangerous exhalations over the country. We believe that we have ol)served that healthy cattle which had smelled of those that were diseased have shown, a few hours after, traces of the contagion. It is known that the ship from Sidon brought the plague to Marseilles, and that the bull which was taken from Hungary to Padua, in 1711, took with it the fearfid con- tagion which first ravaged Italy, and then nearly the half of Europe. It thus appears that the plague of man and the cattle-phiguc take their origin in hot countries, that they can infect temperate regions, and that they are gradually destroyed during the cold of some rig- orous winter. That which is yet a better proof that the pneumonia is perpetuated by infection, as the plague is, is the manner in which we can confine it in suspected places, and by cutting off all commu- nication between the stables which are infected and those which are not. If this malady were generated spontaneously, like the ordinary fevers of man, we would in vain barricade stables, in vain would we slaughter the cattle of a village, and it Avould be useless to isolate the mountains by barriers and guards. All the>e ])recantions would not keep away a disease which has its origin in the blood itself of the healthiest cattle. . . . The contagion, however, does not s])rcad very far, and it does not infect a column of air for any great distance. If the air were infected, if it w;ls able to carry afar the poison of the disease, the barriers and other jirecautionary measures of man would be unavailing. In this there is the greatest resemblance be- tween the disease of cattle and the plague of man. The monks and nuns of Marseilles were saved because they kept their convents closed. The air was not, then, the cause of the disease, else the clos- ing of the convents would not have prevented the pestilence from 256 THE HISTORY OF VETERINARY MEDICINE. entering. The police have often confined this disease of cattle to a stable, or a small number of stables, and so prevented others being attacked. " It follows from all this that, on the one side, the disease arises from infection, and, on the other, that there are no hopes of a cure. There only remain, then, those resources which we may employ to prevent infection, and for confining to the smallest possible limit the loss which might happen when animals are first attacked by this poison. These efforts should be directed to prevent the infection being communicated from foreign countries to ours ; or, if it should have penetrated, then to stop its extension from diseased to healthy cattle. Above all, then, we should hinder the entrance of cattle from a country where the pneumonia nearly always reigns, some- times in one district, sometimes in another, and these precautions ought to remain in force at all times, and be jjerpetual in regard to those countries where the police is not strict, and from which the disease might be carried to ours. The danger will alioays he great if the trade in cattle is carried on without inspection. This precau- tion is all the more necessary against the countries whose rulers care little for the welfare of the people, and in which the people have no confidence in the administration. The poor people of a country, despairing of being aided by the Government, conceal with extreme care the existence of the contagion ; to evade more onerous consequences, they even inter their cattle in the stables ; and it is very natural that they should endeavor to sell at modest prices beasts the keeping of which would only cause the extension of the disease among other cattle. In the countries where the ruler has a paternal feeling for his subjects, where he is always disposed to soften their losses, where he generously takes into account the ex- penses necessarily attending precautions, and where he gains the confidence of the people, the inhabitants at once denounce the disease, submit to the necessary restrictions, and rely on the wis- dom of their king for their preservation and the amelioration of their hardships. A wise government ought to prevent the contagion, and not wait U7itil it has invaded the country, hut check it at its frontiers, where it is easy to do so. The police ought, then, even in times of the greatest security, to taJce care that no animal shall hecome diseased without responsible j^^ople heing informed. Even in ordinary times every animal purchased or sold ought to he vouched for, and should he marked on the horn with a particular stamp for each village, which mark should he renewed whenever it hecomes effaced ; so that hy this proof we may know what village THE HISTORY OF VETERINARY MEDICINE. 257 it comes f/'o/n, and assure oursehrs of tlve health of that village. For the same reason no cattle should be admitted to fairs or markets^ sold or exchamjed, without a voucher being given of perfect healthy impressed and signed by the authorities, testifying to the health of the animal and that of the place whence it came. For this purpose inspectors are necessary. They should destroy cattle which are brought icithout attestation and give the fe.sh to the p>oor ; there are but few cases where less rigorous measures are needed. " 8. Notwithstanding all these precautions, the extent of the frontiers, the want of care on the part of nei^i^hboring nations, the exhalations from the infected mountains where the disease is rag- ing, the greed of gain, and the desire to purchase at a low price, as well as the other failings of a police so difficult to enforce in Inunan society, are all causes which may aid the contagion in insinuating itself into some village or on some mountain. In this unfortunate case it only rests with us to smother the flame in its first commence- ment, and to i)revent its extension. Every j)erson who may have any knowledge of the disease, or even any s^ispicion of its existence among cattle, should be held liable to a penalty if the nearest magis- trate is not at once informed ,' also, ichen a non-suspected beast be- comes diseased or dies, the proprietor or other instructed person should gin' information, and the p7'op>er authorities should then pass on the tidings. Whoever conceals any suspected case should be se- verely punished. Every precaution should then be taken to extin- guish the disease. " 9. The first of these precautions is the prompt separation of the diseased beast from healthy ones. So long as it is suspected, it ought neither to be allowed to drink, feed, pasture, nor dwell with the healthy. It should be kept in a separate stable, or in an in- closed paddock, and those who attend it should wear clothes appro- priate to the purpose, never even approaching healthy animals. The trough out of which this animal drinks ought not to be used for healthy ones, the dung should not be spread on the ground or carried away, but should be buried in deep pits and well covered with earth, and these places should be surrounded with pahngs, so that no healthy beast may be able to smell it. " When the infected animal has been killed, or when it has died, it is necessary to aerate the stable for three months at least, and to remove and bum the thatch, and all the wooden movable articles ; to dig up the ground to the depth of a foot, and rei)lacc it with other earth, and cover the whole with lime. The healthy should not go near the forage which the diseased may have been eating, 17 258 THE HISTORY OF VETERINARY MEDICINE. and whicli might be infected by its breath, though it may be given to horses. Every animal dying of the disease should be opened in the presence of proper persons skilled in the veterinary art, and a report of the ])ost-mortein appearance should be made. If the dis- ease is made out to be a non-contagious one, the owner may be per- mitted to use the flesh and remove the skin. But if there is found the slightest cause for suspicion in the lungs, the skin ought to be cut crosswise, and buried in a grave six feet deep, which should be filled with lime. Palisades should be fixed around it, so that no animal may come near it. If the disease is really a pneumonia, it is preferable not to doctor it, but to kill without delay the first ani- mals which, from their cough, would lead one to suspect the dis- ease, or those which have been in the same stable with the sick ; because we may set down as lost, without exception, every animal which has been in a house with a pulmonic beast. Experience has only too often demonstrated that they take the disease one after the other, and all die. •' 10. When many stables are infected in the same village, the danger is yet greater, and it is here that it is necessary to redouble our efforts to prevent the extension of the contagion. All the in- fected stables should be carefully closed and excluded from all communication with the watering-places and pasturage ; in seri- ous cases, to make more certain, we should kill all animals which have been in the infected places, no less those in apparent health than those in which the disease is manifest. We are driven to this severe course because we can never be assured that those ani- mals which have come out of the suspicious places have escaped the contagion. This apparent cruelty is the only means to be employed for preventing the contagion from penetrating into other stables and into neighboring villages, and from spreading over the whole country. " The case is yet more dangerous when the contagion manifests itself on a mountain where a certain number of cattle find their subsistence during the winter. It has happened that the cattle of the plains have remained in health, but those on the neighboring mountains have been infected, and thus the herds of the republic have been encircled by contagion. In these unhappy circumstances it should be recommended that the mountain-passes be closed, and all communication cut off from the infected pasturage. Inspectors ought to make a visit every fifteen days to the mountains, where cattle belonging to the subjects of the state are kept, in order to examine with great care if any beasts are in a suspicious condition, or if, without exception, they are healthy. THE niSTORY OF VETERINARY MEDICINE. 259 " In those instances wliere the infected mountains of our neigh- bors abut too closely on our own, these last should be most strictly guarded, and it should not be for less than a year after the disease has disappeared that any communication should be allowed ; as ex- perience lias amply demonstrated that cattle not suspected of the disease have been attacked by the contagion by grazing on mount- ains in the neiiirhborhood of those infected. Sometimes we are obliged to exercise a greater degree of severity by destroying the hogs which, according to custom on the mountains, feed with the cattle. The contagion which destroys the cattle does not affect either pigs, sheep, or horses; but it is always to l)c apprehended that these may carry some of the contagion or their infected breath to these animals, and may thus spread the disease. " It is only by these precautions, which should be constantly in force, that it is possible to contine the contagion to a village or mountain, and to keep the country free from infection." That these explicit instructions of the great Ilallcr have not been without their })roper appreciation, may be seen from the following: Professor Putz * (of the Veterinary Institute at Bern) says : '' It is not difficult to determine what regulations are indicated, from a truly scientific stand-point, to suppress the contagious lung- plague of cattle. In order to effectually eradicate the generation of infectious material, the sole generator of tlie pest, there is no more radical method than the complete killing out of the infected herd. A view of the questionable conditions in Switzerland Siitisfactorily demonstrates how advantageous it would be were all the nations of Europe to adopt this plan. In the canton of Bern, noted for its richness in cattle, for about one hundred years (since Ilaller) this scientific procedure has been successfully carried out, and it has finally become universally adopted by the numerous cantons of the Swiss Republic. The law (of February 8, 1872) for the suppres- sion of contagious animal diseases, especially the contagious pleuro- pneumonia of cattle, says, article 2i, ' In Switzerland no cattle that have been diseased with the contagious lung-plague (Ansteckenden Lungenseuche) can ever again be allowed to become an article of traffic' " In M;issachusetts the same course was adopted, at a cost of some seventy-five thousand dollars to the people of the State, but the result has been, that while the disease has prevailed, and still prevails, in neighboring States, not a single case has again appeared in Massiichusetts. * " Die Lungenseuche," etc., by Professor Tutz, " Vortrage fiir Thierarzte," Scries i, Heft 6, V. 7. 260 THE HISTORY OF VETERINARY MEDICINE. As is well known, England has been repeatedly invaded by the rinderpest, which has caused the people to lose millions of pounds in valuable cattle ; while legislation has been wofully im- perfect in this regard, owing to the unfortunate influence exerted by the London Yeterinary School in times past ; still Britain has not been without patriotic and excellent advisers. Among the most noteworthy was a Mr. Bates, surgeon to George I, who wrote in 1714, but his advice seems to have fallen upon barren ground in later years. Bates was appointed by the Government to study the disease, and to devise means for its prevention. He writes, after examining a large number of diseased animals: "We then ordered some of the sick cows to be housed, and several sorts of cattle to be kept with them, to see whether the contagion would affect any other species. The next day I made a verbal report to their Excellencies of all the several opinions and discourses which I have had about it, and left them debating what method to take ; at last I was called in, and ordered to consider it again the next day, and to deliver them in writing what would be proper to be done. Accordingly, I drew up and gave them the following pro- posals : " 1. That all such cows as are now in possession of Messrs. Rat- cliffe, Rufford, and Pullen, be brought, killed, and burned ; or, at least, that the sick be burned, and the well kept secured on the grounds where they now are, that such of them that sicken and die of the distemper may be bunied. *' 2. That the houses in which the sick cows have stood be washed very clean, and then smoked by the burning of pitch and wormwood, and be kept empty three months, at least, before other cows be put therein. " 3. That the fields where the sick cows have grazed be kept two months before any other cows are suffered to stand or graze upon them. " 4. That persons looking after such that are ill should have no communication with those that are well. " 5. That the same methods be observed if any other of the cow- keepers should get this distemper among them ; and that they all be summoned, and told that as soon as they perceive any of the cows refuse their food, or have any other symptoms of this distemper, they immediately separate them from the others, and give notice to such persons as your Excellencies shall appoint, that they may be burned ; and the places where they have stood or grazed ordered as before. THE HISTORY OF VETKUINARY MEDICINE. 261 " 6. That the cow-keejxTs be re<|iiired to divide their cows into small parcels, not more than ten or twelve in a field together; and that they be allowed such satisfaction for complying with these pro- posals as your Excellencies shall think fit." * These suggestions were accepted and acted upon, forty shillings per head being allowed for the sick cows killed by the authorities. '' Some of the cow-keepers a})peared not content with this ar- rangement, and, beUeving that the disease would become general, designed to have their cows sold at some distant markety which the gentlemen having notice of, appointed several butchers to watch near their grounds, and count their numbers every morning, with orders to follow such as were sent to market, and to prevent their being sold by telling the people what they were. " Another great obstacle at fii-st was the cow-keepers not admit- ting the disease until they had lost several cows, for, as soon as it was known that any man had but one sick, no one would buy his milk, and to those who kept many cows the loss was considerable. " Nor was there ever wanting one or other who gave tJuim hopes of cure. " It was endeavored to impress upon the cow-keepers that they would receive remuneration for their losses : ' Tliis had a pretty good effect^ hut here in Englaiul^ where every man is at liberty to dispose of his cattle a^ he pleases^ nothing hut making them sensible that it loas each man^s particular interest to comply lalth these methods^ could do.'' " The entire loss by this invasion was estimated, including ex- penses, at £31,174: Is. Id. In 1717, Jolin Morley, of London, published a satirical poem of this invasion, which may not be without interest : "As soon as Britain had sustained That fatal loss which heaven had gained, And parties squabbled to a maduess About their sorrows and their gladness, A plague unprophesied succeeded. That only reached the horny-headed, And like a fatal rot or murrain Turned all our bulls and cows to carrion. "The farriers now their skill employed, But still the cows in number died, And with their horns and hides together Were burnt, without reserve of leather. * "Animal Plagues," p. 211. 262 THE HISTORY OF VETERINARY MEDICINE. "Some cunning hucksters, who had cows Old, dry, and lean, not worth a souse. Though sound in health, but scarce deserving Of pasture, to prevent their starving. They wisely knocked 'em on the head By night, when neighbors were in bed. Next day assigned their extirpation To this new fatal visitation : So bore 'era to some distant pit Or ditch, for such a purpose fit ; There, to the terror of the isle. Consumed 'em in their funeral pile. Then like true hypocrites, put on A mournful look, as if undone, And claimed the sum of forty shilling For every cow of heaven's killing — A generous bounty, that destroyed More cattle than the plague annoyed." THE establishme:n"t of the vetee- INARY SCHOOLS. There is no doubt tliat many of tlie nations of antiquity had some kind of hospitals for the care and treatment of diseased ani- mals. We have stated, in a previous part of this work, tliat veteri- narians were appointed to watch over the health of the animals used at the circus of Rome, but in this regard the Oriental nations took a high rank from their great veneration for all forms of animal life. Wise says : * " The peculiar humanity of the small and despised community of modern Buddhists, in the country of their ancient greatness, induced them to keep up brute hospitals — Pingra-Pol — which are still to be found in ditferent parts of llindostan. Trevin- nier informs us that he found three or four such houses in Aman- dabab in 1772 ; and Scavoneur gives an account of the Banian hos- pital which still exists at Surat.f " This curious institution is supported by one anna per cent on the rupee of the merchants' clear gain, to which are added the tines for certain venial offenses, under the supervision of the chief Banians. In 1770, when trade had de- cayed, the revenue waa upward of six hundred pounds a year ; and BO careful were they of the animals, that bread and milk were pro- vided for two that could not crop the grass. The ]ios})ital grounds extended over twenty-five acres, and were surrounded by a high wall, and supplied with sheds and wards for the accommodation of the animals. " At the present time there are no hospitals for the cure of hu- man beings when sick, or maimed, or old, because they were sup- posed to be provided for by the Goveniment ; while places are prepared and persons engaged to attend the sick and aged of the inferior animals — proving how much the essential is sacrificed to an * 7yv. ril., Tol. ii, p. 395. f " If proper inrpiirr were directed to this building," writes Princcp?, " I dare .«a.v it would be discoviTC'l to be a lining example (the only one that has braved twenty centu- ries) of the humane arts of Asoka, recorded, at no great distance, on a rock in Guicrat." 264 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. affected refinement of feeling. ISTiebulir found the hospital con- taining horses, mules, cows, oxen, sheep, goats, monkeys, a variety of sick and maimed beasts, poultry, pigeons, and birds ; also an old tortoise, which was known to have been there seventy-five years. In sickness the animals are attended by properly instructed indi- viduals with the greatest care, and here they find a peaceable asy- lum for the infirmities of age. When an animal broke a limb, or was otherwise disabled, its owner brought it to this hospital, where it was always received without regard to the caste or na- tion of its master. There they remained for life, and the only work they were required to perform was drawing water for the pa- tients of the hospital. Above-stairs were depositories for seeds of many sorts, and flat, broad dishes for water for birds and in- sects. " In 1823 Sir Alexander Brown visited the brute hospital at Surat. It is situated in the suburbs, between the inner and outer wall, surrounded by houses and a dense poj^ulation. It occupies a court fifty feet square, to w^hich is attached a large area to admit cattle to roam about, and is strewed with grain and straw, to prevent the inmates wanting either food or bedding. They receive animals of all descriptions, from all countries, as the more numerous they are the more they increase the reputation, happiness, and prosjDcrity of those who support them. In the hospital Sir Alexander found the old, lame, or disabled animals consisted of buffaloes, cows, goats, sheep, cocks, and hens ; some of the latter had lost their featliers. There were cages to protect the birds, but most of them were empty, and a colony of pigeons were fed daily. One of the houses, twenty- five feet long, has a boarded floor elevated eight feet, under which the Buddhists throw a quantity of grain (the oftener the better for themselves), as a work of charity, which in the hot and stagnant air gives life to a mass of vermin dense as the sand of the sea-shore." The Yeteeinary Instftutions of France. It is impossible for me to give more than a very incomplete ac- count of the veterinary institutions of Euroj^e, there being no mod- ern history of veterinary medicine ; hence I have been obliged to collect such information as I could from different articles in maga- zines in my possession, though I have derived great aid from the article entitled " Yeterinaire " in D'Arboval-Zundel's " Dictionnaire de Medecine," etc., Paris, 18T7. I have also been fortunate in pos- sessing two reports of German veterinarians of unquestionable abil- ity, Hertwig and Miiller, who visited France at different times in the THE VETERIN'ARY INSTITUTIONS OF FRANCE. 205 interest of their own Ciuvernineiit. I have myself visited several of the German schools, and also that at Alfort, France. The Continental schools for the stndy and development of veteri- nary medicine were not founded by the respective governments bo much to educate men to practice their profession, as to provide men capable of studying the nature of those fearful pests which had re- peatedly brought poverty to the people, and even threatened nations with ruin, and to discover means for their prevention. In this regard the French schools took a slightly different course from those of Germany, giving more attention to the practical at the expense of the scientific in their education; this reproach is not, however, applicable to the French schools of our day, especially those at Lyons and Toulouse, although that at Alfort has contrib- uted no insignificant amount of scientific work, especially that of the veterinary physiologist Colin, and M. Bouley, the inspector-gen- eral of the schools. At the time when the first veterinary schools were established in France, that nation was approaching the proud position of leader in medical science and culture, which she held for half a century. Bichat, a giant among giants, founded a new sys- tem of anatomy, and died at the early age of thirty-one, a martyr to the cause of science and a benefactor to the world. Cniveilhier, the author of a noted M'ork upon pathology ; Laennec, the author of per- cussion and auscultation ; Broussais, the vampire of medicine, so called on account of the extent to which he advocated bleeding ; and many others, all tended to make Paris a haven toward which men desiring knowledge in this branch of science longingly turned ; longing, not like some American women to go to Paris to die, but for that M-isdom with which her intellectual fountains were so re- pletcly filled. It was but in the order of things that the first veterinary school of the world should be started by a Frenchman, and in France. This honor belongs to an "advocate," Claude Bourgelat, 1712-'79. This young man was educated to follow the profession of law, and studied at Toulouse. Having by his talent won a Ciise which after- ward appeared unjust to him — we wish some of our young American lawyers would follow his example I — he resolved to retire from that profession, and, having from early youth nourished a passionate fondness for the horse, resolved to encourage this tiiste ; in order to do this, he became an officer in a cavalry regiment for a short time, and then chief of the riding academy at Lyons, which soon acquired great notoriety under the guidance of its enthusiastic teacher. The earnest spirit of the young riding-master could not content itself 266 TDE ESTABLISHMENT OF THE VETERINARY SCHOOLS. with studying the outward forms of his equine favorites alone — he must know more ; he must know of the inner powers, the machinery of which this wonderful whole was composed. He therefore gave himself most diligently to the study of equine anatomy as M^ell as physiology, these studies being encouraged by his friend Pouteau, one of the most eminent surgeons of Lyons. At the same time he devotedly studied the writings of earlier veterinarians, and published two works — "Kouveau Newcastle," 1747, and the "Elements of Yeterinary Medicine," 1750. Bourgelat has mistakenly been called a reformer of veterinary medicine ; on the contrary, his was the spirit which gave cause to the birth of scientific research in a branch of medicine which until his time had been nothing but the crudest empiricism. The real science in veterinary medicine did not find birth till many years after Bourgelat's death. He broke the bonds of quackery and superstition to a degree, and gave science room and opportunity to develop. In one thing Bourgelat was indeed wiser than Lafosse, in that he extended his studies beyond the horse, see- ing the necessity of studying the anatomy, physiology, and pathol- ogy of all the domestic animals ; but Lafosse was his superior in intel- lect, in that freedom of mind which evinced itself in his taking an active part for the freedom of his countrymen in the Revolution. On the 5th of August, 1761, through the influence of his friend Bertin, he received permission to found a school in Lyons, the aim of which was to study the diseases of all the domestic animals. The Government supported him with the assistance of 50,000 livres, pay- able in equal portions for six consecutive years. This school was opened to students the 2d of January, 1762, in a small house, for- merly used as a hotel, in a suburb of Lyons called " La Guillatiere." It soon acquired Continental celebrity, and among the students of its first year we find the names of three Danes, three Swedes, three Austrians, three Prussians, three Sardinians, and ten Swiss, all sent to study the elements of the new medicine by and at the expense of their respective goveriiments. The branches at first taught were zootomy, especially that of the horse (exterior), horsemanship, phar- macy, special pathology, surgery, and the principles of sanitary police. Scarcely was the foundation of the school successfully accom- plished, before France was again the seat of the ravages of the de- vastating animal plagues, which gave its students an opportunity to display the value of systematic education, crude as it then was, over the still cruder but futile attempts of a puerile empiricism. The students, guided by the teachings of their master, were so successful THE VETERINARY INSTITCTIONS OF FRANCE. 267 as to attract the attention of tlie king, Louis XV, wlio in an order dated June 30, 1704, gave to the institution tlie title of a " lioyal Veterinary School." A month previously the king had honored Bourgclat with the title of " Director and General Inspector of the Veterinary School at Lyons," and all other such institutions which should be founded in France. The intimate relation which Bourge- lat bears to the early history of the first two veterinary schools of France and the world, makes it almost impossible to treat them separately. Such was the success above alluded to, of the students of the Lyons scliool, in combating the ravages of the animal pests, that the French Government determined to establish a second insti- tution of a like character. It seems ever to have been the aim of the French Government to make Paris the center of French learning and civilization ; hence it was but natural that a point in the vicin- ity of that city should be selected as the site of the second school. Therefore, on the 27th of December, 17G5, a tract of land in the village of Alfort — opposite what is now called Charcnton, at pres- ent connected with Paris by a horse-railroad, and also by steamboats on the river — was purchased for the sum of 32,000 livres, and Bour- gclat called to be its director, which position he occupied until his death. Like the majority of men who give their lives for the devel- opment of science, and in service to their countrymen, Bourgclat died poor, but not unforgotten, as is attested by the immortality with which his name is reverenced in France, and the monument lately erected to his memory by his veterinary successors in France and other parts of the world. From the first, the Government did more for the support of the school at Alfort than that at Lyons, for, while the latter school received but 8,333 livres per year for a period of six years, we find the Alfort school receiving some 12,000. The Abbe Rozier succeeded Bourgclat in the direction of the school at Lyons, which for many years underwent all sorts of vicissitudes, but finally received its full share of acknowledgment, and is at present a most dangerous rival to that of Alfort for the honors with which fair Science wreaths the hrows of her ancresfiful children. Ilavemann,* afterward teacher and director of the Royal Veteri- nary School at Hanover, wa.«i sent by that Government to study vet- erinary medicine at Alfort at this time. While there he wrote the following letter, describing the condition of things, to the master of the Royal Horse at Hanover : * " History of the Veterinary School ot Hanover, from 1777 to 1877," p. 45. 268 THE ESTABLISHMENT OF THE VETERIXARY SCHOOLS. " Alfort by Charenton, Auffust 29, 1777. " The Koyal Yeterinary School has, besides the director, M. Bourgelat (who, however, does not instruct any more, but resides generally in Paris), three teachers. The first, who is known as di- rector and professor, educates in practice and pharmacy ; the second teaches materia medica and botany, and the third anatomy. The majority of the students complete their course in three years, and take them in the following order : '■^ First Summer. — Exterior of the horse. " First Winter. — Osteology and myology. " Second Summer. — On the selection of horses, their care, etc. " Second Winter. — Splanchnology. " Third Summer. — Materia medica and botany. " Third Winter. — Xeurology, angiology, and adenology. " Those students who are blessed with a good memory, and who are able to leara anatomy in two winters, end their course in two and one half years, while many require four. Here no other hooks are in use than those B our gelat himself has written ujjon the subject. The books must be learned verhatirn from beginning to end; in order that this may be complete, one of the older students, who is selected by the director and bears the title of ' chef,' reviews the students each week, and explains and illustrates the various points. TVhen the course is ended, the whole is again repeated before the director, and he who can rattle his books off best receives the pre- mium of a case of instruments valued at fifty livres. " Those who have ended their course practice operative surgery upon the horses which are to be used for anatomy, and also practice horseshoeing in the forge. When not confined by the hours devoted to study, the students may practice in the forge at pleasure. In mak- ing shoes and farriery the instruction is given by a ' chef.' Scarcely any instruction is given in pathology, or the director does it in a very cursory manner when treating of other subjects ; the director seldom detains the students by the sick horses in order that they may study the patients, or to explain their diseases to them, w^hich can have no other result than that the students do not learn to diag- nose diseases, and but few appreciate this great necessity. The medicines are prepared by the students and given by them to the patients. This is done by those who have ended their course, four such being weekly appointed to this purpose. At present there are about seventy sick horses in the hospital, and for each the daily fee is thirty-five sous (forty cents) for medicine, care, and feeding. The THE VETERINARY LNiSTlTUTlONS OF FRANCE. 269 director has exceedingly little to do, and one pei-son can as surely give as good instruction to the students as all three professoi-s. The students are controlled very strictly. Aside from Sundays and Thui-sdays, no students can leave the grounds of tlie school without permission from the director. Everything is arranged by the ring- ing of a bell — getting up, study, attending to patients, eating, and retirinj;. Each student must be in the dissectinjr-room at 7 a. m. in the summer, and 8 in the winter. A chief calls the roll and reports each one who is absent. Each student must remain in this room, or at least on the grounds, and before 11 no student can go toliis room. At 2 r. M. the same course is gone through with, and at G the stud- ies are ended. The students are kept under severe military regula- tion, and the 'chefs' arrange the service of the sub-officers. There are about eighty students here, of whom twenty arc destined for the cavalry regiments ; these have special barracks outside the school, and are under their own officer ; the rest are lodged in tlie school, and, inclusive of meals, pay yearly 3G0 livres. The king pays the professors. Each student, when he goes into the court-yard, must wear the school uniform, which consists of a blue frock with yellow buttons, upon whicii is a lily suiTounded by the words ' Ecolc roiale veterinaire.' The uniform of the ' chefs ' is distinguished by a double golden ' tresse ' upon the collar. The botanical garden is prettily arranged, and contains 0,700 plants. Xotliing seems to have been forgotten which can add to the comfort and beauty of the school." In 1705 the French Government considered the erection of a school at Toulouse for the soutli of France, but it was not until 1825 that the idea came to realization, Dupuy being its first director. This school was intended to give especial attention to the study of diseases of cattle, and if one may judge from the efforts of Toussaint in reference to " charbon," this intention has been most successful. " Alexis Casimir Dupuy * was bom at Breteuil, the 27th Sep- tember, 1775, and died September, 1S40. He was the son of the postmaster of his village. It is without doubt that his intimacy with horses .ind other animals in his youth was the cause of his de- voting himself to the science which he so faithfully served. Ilis first education was received at the college at Beauvais, and later at the college of 'Louis le Grand,' at Paris. In 1792, when seven- teen years old, we find him, with many other young Frenchmen, in the ranks of the revolutionists ; he took part in the battle of Je- * Schracdcr-IIering, loc cit., p. 111. 270 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. mappes, where lie displayed so much courage as to be honored with the standard of his regiment. In 1795 he retired from the army and entered the veterinary school at Alfort. Having passed the requisite examination successfully, we find him, in 1798, acting as assistant at his Alma Mater, and, after passing successfully the re- quired competitive examination, received the professorship of Bot- any, Chemistry, Pharmacy, and Materia Medica. In 1805 he ac- quired the title of Doctor of Medicine, after having devotedly given himself to the study of the necessary branches ; his dissertation treated upon ' Purulent Abscesses and Tumors.' At this time he was very intimate with Dupuytren, so well known in the history of French medicine at this period. He gave his chief attention to the study of pathological anatomy, recognizing the fact that all talk about disease is but mere words, unless one knows intimately of what disease consists. The first product of his investigation in this important branch of medicine was a work which gave rise to much discussion, upon ' Tuberculosis, which is generally called Glanders,' Paris, 1817. Dieterichs, who studied with him in Paris, says that he ' sought to find tubercles everywhere, though no one with healthy eyes could see them, and that he would gladly have seen every dis- ease classed under this one name, so enthusiastic was he in this direction.' His own countrymen seem to have recognized his zeal in this direction." With the opening of the Toulouse school, he was called to be its director, but his mind was so exclusively scientific that he does not seem to have had the attributes necessary to successfully fill such a position, for in 1832 he was discharged, even without a pension. He then removed to Paris, and engaged in practice and the publi- cation of books, but his endeavors do not appear to have been re- warded by success, for he left his family in such a destitute con- dition that the Central Veterinary Society of Paris felt themselves obhged to institute a collection for their benefit. During the extension of the empire under Napoleon I the estab- lishment of three other veterinary schools was considered, but only one came to a positive result — that at Turin, Italy, which is still in existence. The French schools have from the beginning enjoyed a creditable independence from those of medicine, though not without attempts aiming to unite these two branches of medical education. At first they were under the control of the Minister of the Interior, but later have been controlled by the Minister of Agriculture, Com- merce, and Industry, assisted by an inspector-general, that position THE VETERINARY INSTITUTIUNS OF FRANCE. 271 being occupied by the accoinplisheJ M. Bouley, member of the Academy, etc. In the year 1777 the French Government pubhshed very detailed regulations for the guidance of the schools, which have suffered but few modifications to the present day, although their organization as part of a common institution of the land was not fully completed until May 10, 1673, when a decree to that efiect was issued. In accordance with this decree, the students are classed as " Aleves internes," or regular students, " eleves externes," and " auditeurs libres " ; of these, the first form by far the greater majority. On account of the similarity of organization, a visit to one of the three national schools will give an observer a very good idea of them all. The number of professors is the same at each of the three schools, being six, and an irregular number of '" chefs de service," or assist- ants. The professors and assistants receive their appointment from the minister, after having demonstrated their ability by public com- petition for the vacancy in question. These competitions are made known to the public in appropriate publications, some six months before they are to take place. Each competitor must be a French- man by birth or naturalized, and a graduate of one of the national schools. If the competition is for a place as assistant, the person must bring a certificate that he is free from military duty, or that he has permission to present himself for the purpose. The competition is generally divided into five sittings or parts: at the first, the competitors have to present an essay upon some sub- ject in connection with the vacancy which is open ; in the second and third, they have to deliver oral dissertations of a like character ; in the fourth, in connection with any subject belonging to veterinary medicine ; in the fifth, they must show their practical ability in different branches of the profession. The tasks for the second, third, and fourth sittings are made known to the candidates twenty- four hours before each sitting. The candidates for the positions of " chefs de service " must make known their intention of competing one month previous to the date fixed for competition. In the year 1871 the budget ordered for the support of the veterinary schools was G73,000 francs; and in 1873, G56,500. No perquisites are allowed the professors fur examinations, the money received for the same being added to the school funds ; in the place of this the pro- fessors receive 500 francs a year in addition to their regular pay. At Alfort, all officers of the school have free lodgings found them, each professor having six rooms, two being situated on each story of a three-storied building. Each assistant has three rooms at his service. 272 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. In 1876 the corps of professors at Alfort were as follow : M. Keynal (since retired and pensioned), Director and Lecturer on Veterinary Jurisprudence ; M. Gouboux, Lecturer on Descriptive and General Anatomj', Histology, Physiology, and Exterior; M. Baillet, Lecturer on Breeding, Hygiene, Zoology, and Botany ; M. Saunier, Lecturer on Physics, Chemistry, Materia Medica, and Pharma- cy ; M. Colen, Lecturer on General Pathology, Therapeutics, Surgery, Parasitic Diseases, and Horseshoeing ; M. Trasbot, Superintendent of Clinic, Lecturer on Special and Surgical Pathology. The " chefs de service " were M. Baron, assistant to and repeater upon those subjects upon which M. Baillet lectures. He also conducts the ex- cursions to the model farm situated about a mile from the institu- tion, as well as to the cattle and horse markets of Paris, and botani- cal excursions ; M. Barrier, assistant to and repeater of the subjects lectured upon by M. Gouboux, also teacher of histological micro- scopical practice ; M. Nocard, assistant in the clinic and surgery, and demonstrator of autopsies ; M. Baillet, assistant in clinic and surgery. The course of study occupies four years, the lectures lasting one hour and a half each. The sessions are divided as follows : First Session ( Whiter). — Anatomy, physics or chemistry, bota- ny or zoology. These subjects are reviewed by M. Barrier during the session. Second Session. — Chemistry or materia medica, exterior or gen- eral anatomy. Reviewed by M. Barrier. Third Session. — Anatomy, physics or chemistry, botany or zool- ogy, general pathology, and therapeutics. Reviewed by M. Barrier. Fourth Session. — Physiology, general anatomy, botany, micro- scopy, and chemical analysis. Reviewed by M. Barrier. Fifth Session. — Special j)athology, therapeutics, hygiene, general pathology, agriculture ; clinic is held three hours each day on week- days, and two on Sundays. Sixth Session. — Special pathology and surgery, hygiene, phar- maceutical practice, general pathology, therapeutics, parasitic dis- eases, theories of oj^erative surgery, and agriculture. Clinic as be- fore. These subjects are reviewed by assistants Baron, Nocard, and Baillet. Seventh Session. — ^Practice in operative surgery, special patholo- gy and surgery, parasitic diseases, agriculture, forensic medicine, sanitary police, and excursions to the cattle and horse markets. Clinic as before. Subjects reviewed by MM. JSTocard and Baillet. Eighth Session. — Practice in operative surgery, special patholo- THE VETERINARY IXSTITCTIONS OF FR.VXCE. 273 gy and surgery, parasitic diseases, breeding, agriculture, toxicology. Excursions to the model farm. Clinic as before. Subjects reviewed by appropriate assistants. The lectures on agriculture were then delivered by M. lleuze. The subject of dissection luis not been mentioned in the above course, because of the irregularity of the hours devoted to it. The above plan is open to some criticism : one is at a loss to understand why the word " or'' is placed between so many branches, except that the lecturer will dilate upon one '• or " the other subject at the lecture m question. Pathological anatomy is not mentioned, but is treated at the same time with general pathology. Surgery and special ])athology are united in one series of lectures, and the important branch of obstetrics is not mentioned, although we have reason to know it is not neglected. Professor Miiller says that '' when one adds the number of hours devoted to lectures in the four years' course of the French schools, he is surprised to find that they are exceeded by the number required by the (former) three years' course at Berlin.'' The number of professors at the French pcliools is insufficient to do the work well that is requii'ed of them, and they should be relieved by the addition of a greater number of special- ists. We shall see this plan better carried out when we come to speak of the school at Berlin, although there is room for still further improvement there, so far as the clinic is concerned. At the French schools the distribution of the studies over the educational term is not conducive to the best interests of the scholars, too little being required of them during the early part of their studies, and too much toward their completion. This is equalized by the great number of repetitions to which they are subjected by the a^ssistants. Clinical practice and surgery assume an undue prominence in the French system, to the cost of pathological anatomy and the funda- mental elements upon which mcdicid science rests. It should ever be remembered, in establishing a school for the education of men in the principles of medicine, that the hiyhhj-prhed practical man never advances science an iota / he is a money-getter, not a servant of his race ; this has been most empJiaticall y emphasized hy the schools of Britain, where practice has hen the on^ desideratutn, and sci- ence almost totally neglected. The union of both in one person makes the perfect practitioner in veterinary as well as human prac- tice. One might suppose that the clinic of the Alfort school would sofEer from its being so distant from Paris, but this does not appear to be the case, the country around being well populated. At the time of Miilier's visit, which was during the vacation in the sum- is 274 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. mer of 1876, the clinic was restricted as rauch as possible on ac- count of the absence of students, yet there were forty horses and twenty dogs in the hospital. A free clinic is also held daily at the school, and is visited by fifty or sixty patients each day. The sta- bles have room for about fifty horses, and the dog-hospital accom- modates the same number of patients. The school is provided with a special room for operations, with raised steps, arranged in a semicircle, for the students to stand upon. The pharmacy dis- penses the medicines used at the schools, and gives abundant op- portunity for the students to become expert in the knowledge and preparation of drugs. The stables are excellently arranged in the form of a horseshoe, the operating saloon being the center or toe ; two forges also join it, one on each side, the full clinic being held in the space between the wings. The collection of surgical imple- ments at this school is very complete and well arranged. The school fails in not having the ambulatory clinic, common to the Ger- man schools, by which students obtain an acquaintance with much outside, especially herd practice. This is in a measure made up for by the visits which the French students make to the governmental model farms in the vicinity of the schools. The two rooms devoted to the practice of dissection are of middling size, high, and well lighted and ventilated. The anatomical lectures are held in one of these rooms, and there is an amphitheatre for the students to stand upon. Between these rooms is the room of the professor, overlook- ing both by means of windows. The students at Alfort belonging to the first and third sessions have separate rooms for anatomical practice, and also have different lectures. Those of the first session hear lectures upon osteology, sjmdesmology, and myology, and those of the third the remaining parts of anatomy. The practice of anat- omy by the students of the first session is not begun until they have heard lectures on osteology, the dissection practice being limited to muscles and ligaments. The contents of abdominal, thoracic, and cranial cavities are passed to the students of the third session. The students of each class are forbidden to visit the rooms of the other. Both classes are divided into sections of twelve to fifteen students, half of the students of the first and third classes practicing dissection for one week, when not attending lectures, and then the other half, and so on alternately during the winter months. Each section has at its disposition one cadaver, and they are distributed to students of each section as above mentioned. During the week eight cadavers are generally given to the students, and one is used by the professor. Besides these, some twelve to fifteen cattle are THE VETERINARY INSTITUTIONS OF FRANCE. 275 pnrcliiised each year for the study of anatomy. Forty to fifty liorees and ten or twelve cattle are also purchased each winter for the study of operative surgery, and the practice is also kept up in summer. In the coui-se of the year some two hundred and fifty horses are used for these purposes at Alfort. They are hout^ht by the school — the students payin<^ no additioiud fees or buying themselves — and are supplied by a company in Paris, at about forty francs per liead, the same company again receiving the remains after the scliool is done with them. The amount appropriated by the Government for these purposes alone is some eight to nine thousand francs per year, exclusive of the amount paid for cattle. During the fourth session the study of microscopical anatomy takes place ; for this purpose the students are divided into sections of twelve, and practice one week at a time, the specified hours and turns coming round about once a month. The school possesses six microscopes, so that, unless a stu- dent possesses one himself, two students must be appointed to each microscope. The anatomical museum does not make the favorable impression which one might expect from the long existence of the school ; it fails in richness of material and systematic arrangement. The number of normal skeletons is very email, scarcely six being observable. Among them is the skeleton of a thorough-bred horse, which was killed on account of having its forearm shattered by a ball at the time Fieschi made an attempt upon the life of Louis Philippe. The collection contains numerous dried preparations of muscles and ligaments, among them that of a liorse upon which is seated what was once a man and groom at Alfort, who desired that liis body should be preserved in this way. The most interesting and instructive collection is that of the teeth of the domestic animals, arranged so as to show their condition at each year of the animal's life. There are also many interesting artificial preparations of papier-mache and wax. The pathological collection contains a very extensive array of preparations illustrating those processes as they take place in rinderpest. Not more than ten specimens of mon- strosities were observable. The individual preparations are tastefully mounted, but the systematic arrangement is poor. A zoological collection is being begun, owing to the distance of the school from the museums at Paris. A large, well arranged botanical garden helps to make up the appurtenances of the school. The institution has also excellently arranged stables for some twenty-five cows, two hundred sheep and swine. The library of the school contains over ten thousand volumes, mostly French works, however ; it was greatly enriched at the death of the noted veterinary author, llu- 276 THE ESTABLISHMENT OF THE YETERIXARY SCHOOLS. zard, wliose library of some forty thousand Yolumes was pretty well distributed among the three French schools. The school has a special librarian, who also serves as curator of the museum. Students are allowed to read the books at certain hours, but are not permitted to leave the room while there, or to take books to their rooms. Xone but the professors can take books to their residences. The school also possesses a well-arranged riding academy, having some twenty- five hoi'ses, and a riding-master for the instruction of the students. It also has a room fitted up for the students to practice music. The Students. — It has been previously mentioned that the stu- dents are divided uj3 into three classes^ viz., the internal or regular students, the free students, and those known as external students, who come and go as they please. In the summer of 1876, Miiller reports that there were at Alfort 275 regular students, 35 external, and 12 free students — the latter being mostly foreigners. The "eleves externes" are generally students that did not present them- selves at the end of the fourth year for examination, and are study- ing, of their own free-wi]l, the fifth, or those who have been put back one year and lost the support of the Government. For admit- tance, a student must not be under seventeen or over twenty-five years of age. Each student must present a certificate of birth, and the attestation of a doctor that he has been properly vaccinated, or has had the small-pox, and that he possesses a healthy physique, espe- cially that he is free from scrofula ; also an attestation from the supe- rior officer of his locality — mayor or prefect — that he has a good moral character. Students over twenty years of age must also bring a cer- tificate that they have fulfilled their military duties, or been freed therefrom. Their acceptance is dependent upon the consent of the minister having control of the schools. The students present them- selves at the schools for the first time about the beginning of Octo- ber (6th ?), and are then subjected to a matriculatory examination, which consists in writing on dictation something in the French lan- guage, and analyzations of portions of the same ; in arithmetic they must have a knowledge of its principal elements, of the decimal sys- tem, and arithmetical and geometric proportion ; in geometry, a knowledge of its principal elements ; in geography, a general idea of the geography of the world, and a special knowledge of that of France. They also have to write an essay, or something like it, upon history and geography. Special favors are given to those ap- plicants who possess the title of " bachelier es lettres et sciences." For a certain number of students, the " eleves internes," the Gov- ernment supplies lodgings, the school at Alfort affording accommo- TUE VETERINARY INSTITUTIONS OF FRANCE. 277 dation for 275, and generally all these places are occupied. These students pay a yearly fee of six hundred francs for education, lodg- ing, heating, light, board, washing, etc., and the other two classes pay a yearly fee of two hundred francs. Those students that have passed the necessary uiatriculatory ex- amination, and for whom there is not the necessary lodging-room, have the right to enter as external students, not being then subjected to internal regulations of the school ; but few, however, take advan- tage of this privilege, most of them preferring to wait another year for financial reasons, rooms, etc. The exclusion from the " inter- nat," or school boarding-house, is considered the severest punishment which can come upon a student. Only one third of the " eleves in- ternes" pay this six hundred francs from their own means; two thirds of them are the recipients of so-called " demi-bourses," or stipends, which equal the fees paid by the other third. To receive them, however, the student must first have been at the school six months, and have demonstrated his worthiness by appropriate con- duct, diligence, etc. These stipends are paid every half-year, and as a rule are enjoyed by the students during their whole coui-se of study, being only withdrawn in case of gross misconduct or want of proper knowledge, in proportion to the time the recipient has studied. There are three sources from which these stipends come, viz., the prefects of departments, the Government, and the military funds. Each department has two stipends to pay toward the support of one of the veterinary schouls. There are certain regulations to be com- plied with for the reception of the militaiy stipends. The *' eleves boursiers militaires," or military students, receive, aside from the benefits of the " internat," clothing, rent, the necessary books and instruments, and a small amount of pocket-money, in addition to which the Government pays the examination fee of one hundred francs; whereas the other students having the benefit of the " in- temat'' have to pay all such expenses. The military administration provides for sixty stipends, all of which were enjoyed by Alfort pre- vious to 187G, but they are now so divided that Alfort receives thirty and the schools at Lyons and Toulouse fifteen each. The military students, after becoming twenty years of age, are re(piircd to sign agreements by which they promise to serve in the army for five years, but are, during their course of study, generally free from military regulations. The number of students at Lyons and Tou- louse is somewhat less than at Alfort. The whole number of stu- dents at these schools is, in general, about 600, so that each year 278 THE ESTABLISHMEXT OF THE VETEEIXARY SCHOOLS. would give to France somewhere about 150 newly graduated veteri- narians. (The number of civil veterinary surgeons in France was in 1860, 2,760 ; in 1871, 3,036 ; in 1875, 3,019.) Every two or four students at Alfort have a room in which they sleep only, otherwise they are in the study or lecture rooms the whole day ; each year- student having a separate study-room appropriated to his use, ex- cept that the third and fourth year students have a study-room in common. They are allowed certain hours for recreation, in which they are permitted to visit one another in the different study-rooms, or to roam over the court and garden of the institute. The meals are taken in a common room {I'efectoire) at fixed hours, and are good and sufficient. Each Sunday a " bill of fare " is posted in this room for the ensuing week, which has been inspected by the direct- or, and indorsed by him. The students are continually under the eye of certain officers — " surveillants " — who have their discipline in charge during the hours of study. On Sundays the students are permitted to go outside the school, the roll being called at 11.30 p. m. On the first Sunday of every month they are allowed to remain out until 12.30, that they may attend the theatres in the city. They are only allowed to receive visitors at certain hours, and in rooms near the gate appointed for the purpose. On entering the school one is immediately struck with the peculiar blue frock worn by all the stu- dents, which would, however, give a far better appearance of uni- formity were they obliged to wear the same form of hat or cap. There is no state examination at the French schools as in Ger- many ; on the contrary, the students are subjected to repeated ex- aminations by the assistants, and at the end of each session by the professors in their respective branches. The result of these sessional provings is, that students found unsatisfactory are put back for a year in their course, and lose the advantages of the " internat," or are sent from the school. The final examination for the diploma of the French Government is simply a more extended sessional examination. Of late, the professors have been ordered by the Government to prove the students in the branches of the first two sessions of their course. This examination is further distinguished from the ordinary sessional in that each student must attend to two sick animals in the hospital and perform three operations. (It should be mentioned here that in the French schools, other Conti- nental schools also, the students have a certain number of patients under their entire charge during the whole course of their hospital practice, being simply guided and questioned by the clinical teach- ers. This amounts to the same thing as being in practice while THE VETERINARY INSTITUTIONS OF FRANCE. 279 studyinf]:, and offers the great advantage of a competent advisor and consulting assistant.) Aside from an anatomico-pliysiological essay, the examination is entirely oral. Each professor hands in an account, with reference to each student examined, in the form of a number, which is inclosed and sealed ; these numbers are then added together in a somewhat complicated manner. Ilertwig, who visited the French schools in 1S71, in speaking of the veterinary condition outside the schools, says that the civil veterinarian is entirely dependent upon his practice for a livelihood, there being no civil official veterinarians, as in Germany, occupy- ing positions for which they are paid by the Government. Miil- ler, who visited the school in 187G, and whose report I have mostly followed, also says the same thing ; " but that in some depart- ments there are so-called ' arrondisseraents' which receive from the communal funds from three to six hundred francs per year, but they are not connected directly with the Government, and their pay is yearly resumed." A revision of the " Laws and llegulations of France for the Prevention and Suppression of Contagious Animal Diseases" has lately been made by the Government (1879), but I have failed to see any indication of the division of that country into departments and districts, with its appropriate government veterinarian, as we shall see is the case in Germany when we come to speak of the veterinary institutions of that country. Such may be in contemplation, however, and will be a great gain for the pro- fession in that country. There are, however, municipal and local veterinary officials stationed as inspectoi'S of markets, horse-fairs, and the like. Notwithstanding most earnest remonstrance on the part of the veterinary profession of France for many years, tlie Government has not yet taken the steps it should for the protection of the holders of its own diploma, by enacting laws for the suppres- sion of quackery, which renders the task of gaining an honest living unnecessarily difficult for the graduated members of the profession, for the quack is ever ready with infallible cure-alls, and is ever such a glutton and an unprincipled wretch that he will work for any fee, no matter how small ; and, on the other hand, frequently gets fees for services rendered which a graduated man would scarce have the effrontery to ask. All that the Government does is to make known in a public print that the veterinarian is the holder of a government diploma when he settles in a district to practice. These conditions are made still more onerous by the large number of graduates which are yearly turned out from the schools. "In 1871 the department of the Seine, inclusive of Paris and the school at Alfort, and several 280 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. military veterinarians, had 115. Of these, four were attached to the Ministry of War, two to the omnibus companies, one as in- spector of the horse-market, two as inspectors at the slaughter- houses, one to the market-police, and one to the court stables. " The military organization is, on the contrary, well arranged, and the army veterinai'ians are well placed, both in regard to their rank and pecuniarily. According to the decree of 1860, the French army had in all its departments 337 veterinarians, who enjoyed the following positions : 4 principal, 120 first class, and 128 second class, and 25 assistant veterinarians. The yearly pay of the chiefs was 4,000 francs, and that of the assistants 1,800. When the chiefs were retired, they received a pension of 2,340 francs, which could be increased to 3,744. Two of these veterinarians were members of the commission ' d'hygiene hippique ' at the Ministry of War, and a third was veterinary to the Guards, and resided in Paris. A fourth was stationed as superior veterinarian at the cavalry-school at Saumur, and a fifth in a similar position with the troops and royal stud in Algeria, under the rank of ' etat major.' The other three classes have also the rank of officer, with corresponding pay : for the first class, 1,700 francs as minimal, and 2,760 as maximal ; the second class from 1,400 to 2,800 francs ; and the assistants from 1,300 to 2,112 francs. On the other hand, the value of veterinary science has been from the early days of schools well acknowledged by the members of the Academy and other scientific societies in France, and members of the profession have taken no second rank among the scientists of France and the world. At the present day the literary-scientific horizon of France has no more refulgent lights than Chauveau, Toussaint, Bouley, Colin, Megnin, and other mem- bers of the veterinary profession." The Yetekinaey Institute at Vienna, Austria. With the termination of the school-term for 1877, this institution began a second centennial existence, and it is to be hoped its pros- perity and usefulness will go on increasing as the years pass on. The school is known as the " Eoyal Military Veterinary Institute of Vienna." Professor Dr. Roell, its late director, gave a complete sketch of its history for the first hundred years of its existence in the " Oesterreichse Vierteljahrsschrift fiir wissenschaftliche Vete- rinarkunde," vol. xlviii ; to which are added lithographic illustra- tions of the grounds and buildings. This periodical (quarterly) has been issued by the faculty of the institute since the year 1851, and contains many articles of value. The establishment of this school THE VETERINARY INSTITUTE AT VIENNA, AUSTRIA. 281 was preceded by tlie openinp^ of a scliool for the treatment of the diseases of the horse and operative practice in 17»)4, with the con- sent and support of the Government, by an Italian named Luigi Scotti, who, in company with an apothecary named Meno;mann, was sent by Maria Theresa to Lyons to study the principles of veterinary medicine. I)urin<2; this visit to France Scotti received 420 guldens each year from the (xovernnient. On their return they presented the Government with a proposal for the erection of a school, and recommended a course of two years, considering the study of anatomy as the most important subject. They recommended that tiie students be taken from among the experienced smiths of the army, that could read and write, and felt confident that they could make competent vetennarians in the time mentioned. Ac- cording to their plan of instruction, general anatomy, osteology, and exterior, were to be taught in the fall, as well as horse- shoeing, upon which great stress was laid ; in winter, myology and practice in horseshoeing ; and in spring and summer, a knowledge of the useful plants, their preparations and use. The second year was little more than a repetition of the first, with the exception that the students were made acquainted with disease and its treat- ment by hospital practice. There were but two teachei-s attached to the school, which was opened January 12, 17G7, the whole being under the supervision of a military ofticial, who attended to the gen- eral order, cleanliness, and deportment of the students. The pur- pose of the school was limited to the education of better qualified smiths for the army, and only army horses were treated therein. The students were taken for the full two-years' course, and only at the exjiiration of the same were new students taken. While this horse-school was still in active operation, J. Gottlieb Wolstein, surgeon, and a selected military farrier by the name of Schmid, were sent by the Minister of War to Alfort, to carefully study the principles and practice of veterinary medicine as there taught. Both of them were paid by the Government, as well as hav- ing an allowance for the necessary expense, in return for which they were obliged to bind themselves for life to serve the Government, and on their return "Wolstein was named as professor and Schmid as assistant, Schraeder* says : " Job. Gottlieb AVolstein, Doctor of ^ledicinc and Surgery, was bom at Flinsberg, in Silesia, March 14, 1738, and died at Altona, near iraml)urg, July 3, 1820. lie at first gave his attention to the study of surgery for nine years at Vienna, and * Loc. eil., p. 476. 282 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. in 1769 was sent to France by the Austrian Government to study veterinary medicine under Bourgelat and Cbabert, where he at the same time studied human medicine in the Paris hospitals, as well as taking an active interest in the work of Lafosse between the years 1772-'73. In 1773 he visited London, and, on his return to Austria, Denmark, Mecklenburg, Holland, and in 1779 took the degree of Doctor of Medicine and Surgery at Jena. The school at Vienna bore witness to the practical abilities possessed by Wolstein. In the year 1795 he received his discharge from the Yienna school, but it is not known whether it was owing to his free-thinking tendencies (for he was the first Protestant who received an appointment in the state service of Austria), or to other circumstances. Wolstein was a most extensive author, nearly all his works bearing testimony to his clear-headedness and practical ability. Among other things, he was the first to establish the causal connection between an accumu- lation of fluids in the lateral ventricles of the brain of the horse, causing the condition known in German as " DummkoUer " ; French, "immobilite" ; Latin, "amentia." He also wrote a book upon the " Scientific Breeding of Human Beings." On his return to Austria he gave the Government his ideas with reference to the formation of a veterinary school, and on the 23d of July, 1777, he received from the Government 13,740 florins toward the erection of the school ; and on the 26th of December, 1877, the Government issued the instructions for the regulation of the school, which was soon opened. The personnel of the school at this time consisted of one pro- fessor, one superior assistant, two assistants, and a number of half- invalided soldiers, necessary to the care of the animals in the hos- pital ; also one inspecting officer, and one farrier. The school and hospital were placed under the control of the Minister of War, and the supervision given to a brigadier. In the buildings were pro- vided lodgings for the teachers of the school, and seventy army farriers, as students. To the school belonged a botanical garden, an anatomical saloon, a lecture-room, dispensary, laboratory, and library ; a smithy with four fires ; four stables, with room in each for seven horses ; fifteen separate stalls (probably boxes), and a small stable for cattle and sheep. The instruction was divided as follows, and extended for two years : Professor Dr. Wolstein lectured upon the theoretical and prac- tical application of the principles of medicine to the diseases of the horse. First Assistant Schmid lectured upon horseshoeing, and demon- THE VETERINARY INSTITUTE AT VIENNA, AUSTRIA. 033 ptrated and supervised operative surgery, and represented Wolstein when the latter was unable to be present. Assistant Toegl (1779) demonstrated anatomy, and Men<^mann controlled the pharmacy, and lectured upon medical botany and pharmacy. The military students came either from cavalry regi- ments or were selected by the school from among young smitlis who displayed unusual ability. The students must be under thirty years of age, unmarried, natives of Austria (Hungary also ?), of pei-fect physi(|ue and good moral education, and be able to read and write in the (rerman language. The admittance of civil students was dependent upon the judg- ment of the teachers, who were made responsible for the ability and character of the same. P>om 177S to 1790, 178 military, 137 civil, and 144 foreign students graduated at the school. During this period, 4.2<)8 army horses were treated, of which 3,6l)5 recovered, 201 were discharged uncured, and 252 were killed. In 1806 numerous changes were made in the buildings and some in the curriculum, the intention of the school being to educate superior and ordinary farriers for the army, '•Kurschmieden " (farriers edu- cated in the principles of medicine), veterinary surgeons, and ordi- nary farriers. The course was still continued at two years : in the tirst year, horseshoeing, anatomy, pharmaceutical chemistry, physi- ology, exterior of the horse, breeding ; in the second year, therapeu- tics, pharmacology, and veterinary police. The military students were compelled to work from G to 11.30 a. m. and from 3 to 0 p. m. in the forge. The personnel of the school was increased by a pro- fessor of pathology anhysiology. The faculty consisted of five professors, receiving 2,000, 1,500, 1,200, and 1,000 florins each, with free lodging and other perqui- sites ; also four assistants, receiving 700, GOO, 500, and 400 florins. On the ITth of November, 182.3, the corner-stone of the new school was laid with appropriate ceremonies, and in the presence of many of the nobility and noted personages. In this year the com- mencement of a library was begun in earnest by an appropriation of three thousand florins, but at the present day a yearly sum is appro- priated to the purpose. In the year 1835 an institution for experi- ments with reference to the variola of sheep was added to the in- stitution and continued until 18G4. In the year ISJf!) the institution was separated from the university., and has since remained indejyetv- denty sidject to the control of the Ministry of ^Yar. In 1871 the cur- riculum again suffered revision, and wa.s placed in its present form ; the purpose of the school being to educate civil and military vet- erinarians, and also civil and military horseshoers j aside from this it jnust do its vtmost to forward I'eterinary science, and is the highest technical authority with reference to contagious animal dis- eases and thiir suppression. The director also acts as adviser in all things with reference to the military veterinary institutions at the Ministry of V^at. The guidance of the school is dependent upon the director and the military supervisor. The latter is directly sub- 286 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. servient to the Minister of War, and conducts tlie institute in its re- lation to the military organization, supervising the internal arrange- ments and the discipline of the servants and students. The director controls the scientific-technical parts of the institution. The teach- ers are represented by professors, docents, adjuncts, assistants, and a teacher of horseshoeing. The number of professors is limited to six, one of whom is director. The subjects taught are as follow, divided among the following professors and assistants : Director (1877), Moriz F. Eoell,* and Lecturer upon Animal Pests, their Causes and Prevention ; also Conductor of the Inner Clinic. Professor Franz Miiller, Lecturer on Zootomj', the Theories of Shoeing, Exterior, and Conductor of the Dog Hospital. Professor Andreas Briickmiiller (recently deceased). Lecturer on Breeding, Obstetrics, and Zoophysiology. Professor Briickmiiller is the author of the only text-book extant on " Animal Pathological Anatomy," which is too largely founded upon Pokitansky to be un- critically followed at the present day, however. Professor Franz August Armbrecht, Lecturer on Yeterinary Surgery and Operative Surgery, and Conductor of the Surgical Clinic. Professor Leopold Forster, Lecturer on Special Pathology and Therapeutics, Pharmacology, Pharmacognosy, Botany, Instruments and Bandages, their Uses and Application. Professor Franz Zahn, Lecturer on General Pathology, Patho- logical Zootomy, and Forensic Medicine. The lectures in Chemistry are delivered by Professor Dr. I. Moser, of the Agricultural Academy. Adjujicts. — Max von Paumgartten, Assistant Lecturer on Zo- otomy, Exterior, and Theoretic Horseshoeing. Eaimund Koezil, Assistant Lecturer on Path.-Zootomy, Forensic Medicine, and Cattle and Meat Inspection. Franz Konhauser, Assistant in the Medical Clinic, and Teach- er of Special Pathology and Therapeutics. Josef Bayer, Assistant in the Surgical Clinic, and Teacher of Veterinary Surgery and Operations; also Lecturer on Yeterinary Literature and History. Johann Csokor, Assistant-Lecturer on Breeding and Zoophysi- ology. Assistants. — J. P. von Froschauer, to the Medical Chnic. Josef Stengel, to the Surgical Clinic. * Since retired and pensioned. THE VETERINARY INSTITUTE AT VIENNA, AUSTRIA. 287 Franz Wildner, on Descriptive and Patholof^ieal ZoOtomy. Over-Vcterinariaii F. Scliuller, Teacher of Horseshoeing. Inspecting Veterinarians. — Ferdinand AVicher, for the Hospitals. Anton Janich, for Horseshoeing. Accountants. — Franz Miihhi, Superior. Heinrich Liizlo, Assistant. Other Perfions. — One gardener, two otficial servants, one porter, three saloon-servants, one apothecary's servant, one watchman, two drivers, three smiths in forge, three corporals, and forty-one soldiers as servants in the stables. The ground of the school covers a territory of 42,514 square metres. It is ])lentifully supplied with fresh water. The stables contain room for eighty horses, besides twenty-two boxes, with grain magazines, rooms, and all necessary appurtenances. There is also a stable for fourteen cattle, and the dog-hospital is fitted up with cages for forty -four dogs. There is also a quarantine-stable for the isolation of suspected or diseased animals, with five boxes. The school has a tine botanical garden, lecture-room, laboratories, muse- ums, forge, grazing-ground, and everything necessary to such an in- stitution. The number of works in the library is 4,132, or 9,030 volumes, six to seven hundred florins being allowed for its repletion each year. The books are all arranged, according to the subjects treated, upon appropriate shelves. At the end of the year 187G the anatomical museum contained : Stuffed mammalia and monstrosities 160 spec " birds 59 Skeletons : Mammalia 100 Birds 62 ' Amphibia and reptiles 10 ' Fishes 1) ' Individual bony specimens 3CG ' Teeth 428 Lipaments, cartilage, and muscle preparations 95 ' Intestines 156 ' Nerves 27 ' Blood- vessels IGO ' Lymphatics 8 ' Monstrosities in spirit 110 ' Embryos 129 Varia 115 Total 2,084 The pathological museum contains 2,762 specimens. The col- 288 THE ESTABLISHMEXT OF THE VETERINARY SCHOOLS. lection of surgical instruments is very complete, 224 new ones being added to it in the last twenty years. The collection of herbs, minerals, etc., used in medicine, and all other appurtenances of a school of like nature, are kept full and in perfect order. During the years between 1823 and 1877, 100,558 animals (of these 87,436 recovered, 8,787 died, and 4,281 were killed), with the exception of dogs, were treated at the school, being 1,845 for each year. From 1857 to 1877, 20,241 dogs were treated in the dog-hos- pital, of which 14,023 recovered, 4,725 died, and 1,463 were killed. The Students. — The students belong either to the civil or mili- tary professions. The first are either students of veterinary medi- cine ])er se, or of horseshoeing. IS^either the Minister of War nor his representative, the military supervisor, exercises any control over them, they being subjected to the control of the directors, and all regulations concerning them emanate from the " cultus " minister. The conditions for admittance are : 1. At the military veterinary school the students are educated in the entire principles of veterinary medicine. 2. "Whoever intends to become a student must subject himself to a matriculatory examination. This examination is not required of students that are graduates of the sixth class in a " gymnasial " or " real " school. (The matriculatory examination is limited to the following sub- jects : German language, physics, chemistry, natural jiistory, geog- raphy, history, and algebra.) In the German language the student must write an essay in good, clear orthography and good grammar, upon a subject of nat- ural history. Physics. — He must explain and demonstrate npon instruments the ordinary phenomena. Chemistry. — The elements of inorganic and organic chemistry, with simple tests. Natwal History. — General knowledge of the classification of the three kingdoms. Geography. — Physical geography in general, and the climatical and geographical conditions of all parts of the world, and a special knowledge of Central Europe, and Austria in particular. History. — A knowledge of the chief historical events of the world at large, and Austria in special. Algebra. — Elementary. THE VETERINARY INSTITUTE AT VIENNA, AUSTRIA. OgQ This exiuniiuitiun takes place in the first week of October of each year by a special commission named by the '' cultus " minister, three members being professors of the school, and one each repre- senting a gymnasium and real school. The examination costs five guldens, and goes to the examiners. Students must not be over twenty-six or under eighteen years of age ; consideration is some- times taken in case of students whose studies have been uninten- tionally interrupted in a scientific or agricultural academy. The course extends over three years, of two sessions each, as follows : First Tea?' {First Session). — Introduction to the study of veter- inary medicine for two weeks, three hours each week ; zootomy of all domestic animals, weekly, five hours; general chemistry, weekly, three hours ; breeding, weekly, three hours ; theoretic horseshoe- ing, weekly, two houi-s ; dissection and practical horseshoeing, ar- ranged in the hours not taken up by other branches. {Second Sessio)i.) — Topographical zootomy, weekly, five hours ; organic chemistry, with especial reference to physiological and pathologiciil chemistry, weekly, three hours ; breeding, five hours ; medicinal botany, weekly, two hours ; dissection and practical horse- shoeing, as before. Second Year {Third Session). — General pathology and patho- logical anatomy, weekly, three hours ; physiology with microscop- ical practice, weekly, two hours ; pharmacognosy, materia medica, and art of writing prescriptions, weekly, three hours ; clinic, daily ; dissection, and the preparation of two anatomical subjects, in hours to be fixed at convenience ; autopsies ; practical horseshoeing. {Fourth Session.) — Pathological zootomy, weekly, three hours ; physiology, with microsco])ical practice, weekly, two hours ; ob- stetrics, weekly, two hours ; theoretic use of instruments and band- ages, weekly, two hours ; clinic, daily ; autopsies ; practice in chem- ical laboratory ; horseshoeing. Third Year {Fifth Session). — Medical and surgical clinic, daily ; special pathology and therapeutics, weekly, three hours ; veterinary surger}', weekly, two hours ; practice in operative surgery, weekly, three hours ; exercise in making reports of forensic cases and in reference to veterinary police ; animal pests and veterinary police, weekly, three hours ; cattle and meat inspection, weekly, one hour ; horseshoeing. {Sixth Session.) — Clinics, and other branches as before ; history of veterinary medicine, weekly, one hour ; horseshoeing. The school also has a special course of two years for medical men and wound-doctors. 19 290 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. The Examinations. — The examination takes place at the end of each year in the subjects which have been lectured upon or demon- strated. The results are designated as " excellent " (" sehr gut " *), " good," and " middling." Students who have received the last censor may apply for a second examination, but those who have re- ceived it in two or more branches are obliged to repeat the full course for the completed year. The professors are free to make examinations on any subjects during the session. Students who desire the state diploma as veterinarians must, among other things, make an autopsy and correctly dictate the re- sults ; also prepare certain anatomical specimens, and give in to the appropriate professor certain written documents upon cases in con- nection with forensic medicine and veterinary police. Aside from this, the final examination consists in the student attending a selected patient (a tough case selected by the teacher) in both the internal and surgical clinic for three days, of which the student has to make, unaided, the diagnosis, and attend to and direct the treatment, and write a full description of the case, its history, treatment, and prognosis. Further, he must make several surgical operations upon a living animal, and demonstrate a subject in anatomy. The partial examinations take place under the special professor in each branch, with changes of professors, the last examination in the presence of the whole examining body. All members of the examining commissions are free to ask of the candidate any ques- tions they please in connection with veterinary medicine or its col- lateral branches. The examining commission consists of the pro- fessors and a person named by the Minister of the Interior. If a candidate has failed in one part of his examination, he may again present himself at a time fixed by the commission, which can never be in less than three months. If he has failed in two divisions of the examination, he must be examined again in all parts of his studies, but never in less than six months. The final examination costs fifty-four florins. Foreigners are admitted by the consent of the direction, and have a right to an examination for a diploma, hut not to jpractice in Austria when not naturalised citizens. Foreigners have to pay twenty guldens fee for each session before it begins. Single courses of lectures may be arranged with the director. Certain rules of conduct must be observed. * The German " sehr gut '' is not correctly interpreted by the English " very good" it being spoken with a peculiar emphasis, and used only in a sense of the English " ex- cellent." VETERINARY SCHOOLS OF HFLCHM, Rr>^SIA, SWEDEN, ETC. 291 Some fifteen years ago the scliool at Vienna enjoyed a very high reputation in Europe. BriiekniuUer was then a first-ehass authority. IloL'll hud made himself famous by his clinical ability, especially with reference to jmlmonary disease, and is accredited with being the first to systematically introduce auscultation and percussion of the chest into veterinary practice ; but all things must fade: the pro- fessors have grown old and lost some of their youthful energy, and at present their places have not been filled by "young blood," so that this once famous school is in a sort of semi-torpid condition. Nearly all schools of medicine and science have to undergo these changes, so that we may be sure that the Vienna school will ere long assume its old rank among the bright sisterhood of European veterinary in- stitutes. Short Notices of the Veterinary Schools at Brussels, Bel- gium, AND those of Russia, Sweden, and Norway. The small kingdom of Belgium was by no means to be outdone by her larger sisters, and ranks high among the Continental nations in reference to its veterinary institutions. The Royal Veterinary School was instituted in 1832, but not organized until 1835, and is situated in the environs of Brussels ; one of the streets bounding it on one side is named after Brogniez, one of its most distin- guished professors, who added many valuable instruments to the veterinary cabinet. Among other noted professors who have been attached to this school we find the names of Thiernesse, AVehenkel, and Dupont ; and, among the practitioners, Willems, the introducer of inoculation as a prophylactic against pleuro-pneumonia in cattle. The Bnissels school is modeled after those of France ; the fee for the regular students (eleves internes) is fixed at TOO francs per year. The preliminary education denuinded of students is higher than in France, the consent of the minister being necessary to their admit- tance. !Many young men study the natural sciences at this school, who intend studying medicine at the university, thereby enjoying the advantages of the " inteniat." The number of teachei-s is larger than at the French schools, there being eight professors and four assistants. The number of lectures is also greater. There are two examinations — one at the end of the first two years, and the other at the completion of the course, which extends over four years. The hospital has room for about thirty horses, each one paying a fee of two francs daily. The school has a visiting clinic, but no school conveyance, the visits being made, however, at the expense of the in- stitution. Three horses are weekly used for anatomical and opera- 292 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. tive practice by the students, and one for the anatomical teacher ; they cost some eighty francs each ; about eighty animals are used in this way each year. The anatomical museum is very rich in specimens, and they are better arranged than at Alfort. The four-year course is arranged as follows : First Session. — Anatomy, dissection, physics, botany. Second Session. — Botany, physics, repetition in anatomy, and the two foiTner subjects. Third Session. — Anatomy, dissection, physics, chemistry, with reviewings upon the two latter. Fotirth Session. — Anatomy of the domestic animals aside from the horse ; physics, histology, chemistry, horseshoeing. Fifth Session. — Clinic, pharmacy, general and special pathology, anatomy, operative surgery, therapeutics and materia medica ; the- ory and practice of horseshoeing. Sixth Session. — Clinic, general and special pathology, anatomy, pathological anatomy, therapeutics and materia medica, pharmacy, with practice, operative surgery, horseshoeing. Seventh Session. — Clinic, surgical pathology, horseshoeing, breed- ing, topographic anatomy, operative surgery (theoretical and practi- cal), pharmaceutical practice, forensic medicine, and sanitary po- lice. Eighth Session. — Clinic, surgical pathology, breeding, obstetrics, meat-inspection, pharmacy, horseshoeing. Numerous repetitions or reviewings of each branch of study take place during each session. The regulations for the control of the Government veterinary officials are about as follows — I say "about," for they are taken from the law of 1851, and some changes may have since been made: Article 1. According to the requirements, there shall be one or more Government veterinarians in each agricultural district. These veterinarians are named by the Minister of the Interior, on the proposal of the permanent deputation of the provincial coun- cil, and the agricultural commission ; the minister fixes their residence, and the territory over which they shall exert control. Art. 2. The Government veterinarians are generally selected from among those who have passed an especially satisfactory exami- nation at the school. Akt. 3. Each appointment is at first made provisory for a period of tliree years, and only at the end of this term can the ap- pointment become permanent. Abt. 4. In those districts where the rewards of practice are in- VETERINARY SCDOOLS OF BELlilUM, RUSSIA, SWEDEN, ETC. 293 sufficient, the minister may allow the veterinary official a support whicli shall not exceed three hundred francs yearly, in addition to that allowed by the local authorities. Art. 5. The duties of the Government veterinarians are : 1. To exert a careful supervision of the hygienic conditions uf the animals in their district. 2. To watch over the healthy condition of the stal- lions used for breeding, and to see that they arc adapted to the pro- vincial regulations for the improvement of stock, 3. They must carefully investigate all animals in their district with reference to contagious or infectious diseases. 4. At the requisition of the gov- enior of their province, they must visit public markets and fairs and watch over the health of the animals. Art. G. Such veterinarians as are members of the provincial agricultural commission control, when required by the governor or Bald commission, the official duties of the other Government veteri- narians of the province. Art. 7. It is their duty to notify the commissioner of the "ar- rondissements," and the members of the agricultural commission, of the presence of contagio-infectious diseases in their province. The governor of the province receives his notification from the above- named officials. In important cases the Minister of the Interior is also to be notified by the General Inspector of Hygiene, who is notified directly by the veterinary official. Art. 8. The Government veterinarians are also obliged to ob- serve the conditions of agriculture in their respective districts, so far as their other duties will permit of, and to make reports to the Min- ister of the Interior, Art. 0. These officials must make official returns within the first ten days of each quarter to the governor of the ]>rf»vince, with reference to each case of an infectious or contagious animal disease that has taken place during the past quarter in their district, and also with reference to all other facts which are of importance to the Government. These reports are collected by the Provincial Agri- cultural Commission, and sent by them to the governor, whr» in his turn sends them to the minister. The General Inspector of Public Hygiene must return a yearly report of all cases of contagious ani- mal diseases which have occurred in the kingdom. Art. 10. The Government veterinarians liave exclusively the control of the infectious animal diseases, and must always be called upon to make such examination by the higher officers of the Gov- ernment, Art. 13. Such officials can only order the peremptory killing of 294 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. an animal when it is affected to an incurable (?) degree with the following diseases : Horses. — Glanders. Cattle. — Anthrax, rinderpest, and plenro-pneumonia. Sheejp. — Yariola, and in all animals when complicated with rabies. The rank and advancement of veterinarians in the Belgian army are as follow : The veterinary inspectors rank as major; the first-class veteri- narians as captain ; the second-class veterinarians as first lieuten- ant ; the third-class veterinarians as second lieutenant. In order to become a third-class veterinarian, the applicant must have graduated well for a civil veterinarian ; must be twenty-four years of age, and a citizen, or naturalized. No one can become second class without having served creditably in the third for at least two years. To become first class, he must have served in the second for at least two years to the same degree. As inspectors, three years' first-class service is necessary. To be first or second class, the applicant must also stand a practical examination. The inspectors are appointed by the king. Yeterinarians of all grades receive, after ten years' active service, one fifth more pension than army oflBcers having a corresponding rank. Russia.'^ We are somewhat inclined to look upon the Russians as a sort of lialf-civilized people, but the reverse is much more near to the truth, at least so far as it has reference to the support given by the Govern- ment to the advancement of science. In no way is this more true than in relation to veterinary science, the need of which made itself apparent very early in this century, on account of the wealth of the nation in domestic animals, especially cattle, horses, and sheep. As should be known to every one, rinderpest, the most terrible and devastating of all animal plagues, makes its home upon the steppes of Southern Russia, causing yearly a loss of thousands of cattle, and frequently extending its ravages to neighboring countries. In 1877 the official returns of the losses caused by rinderpest are given as 217,768 cattle and 1,884 sheep; and the same authority gives as the number of cattle in the empire, 25,918,600 : the loss from this cause amounting, therefore, to 0'82 per cent. Russia has three veterinary institutes, one each at Kharkov, Dor- pat, and Kazan, all supported and regulated by the Government ; the degrees given are doctor and magistrate of veterinary science. The * Miiller, " Russische Veterinar Institut Magazin," vol. xxx. VETERINARY SCHOOLS OF BELGIUM, RUSSIA, SWEDEN, ETC. 295 regulations for these schools suffered a complete reorganization soon after the veterinary congress at Frankfort in the year 1872, the aim of the Government being to make them second to none in Europe from a truly sclent Ijic poiiit of view. The new regulations bear date May 8, 1873. The schools are subjected to the control of the cultus minister in the tirst place, and directly under the curator of the educational district in which they are situated. The immediate direction, however, consists of the director and council of the school. At each institute there are three regular, one extra profess- or, four docents ; of the last, one for pharmacy, one for agriculture, one prosector who is also a docent, and an extra prosector and a teacher of horseshoeing, with various assistant teachers. The direct- or receives, aside from a free residence, 3,300 silver rubles yearly ; the regular professors, 3,000 ; the extra, 2,000 ; the docents and pro- sectors, 1,200 ; the assistants, 700 ; and the teacher of horseshoeing the same, with residence. The director, professors, docents, and prosectors must all have the qualification of a magistrate of veteri- nary science. The docents of pharmacy and agriculture must like- wise be of the same grade in their respective branches, but the teacher of horseshoeing may have only the ordinary veterinary diploma. Private docents are also permitted to lecture upon any branch of veterinary science which they may select. To these last the qualification of doctor of veterinary medicine is necessary, but each aspirant must write an essay upon a selected subject, which must be publicly defended, and also stand two test-examinations upon themes selected by the council of the institute. The private docents have no certain pay, but the same is regulated by the council, and they have before them the privilcije of adding to their education bv study in foreign countries at the Government's expense. The natural sciences — mineralogy, botany, zoology, comparative anatomy (not zo- otomy), physics, physical geography, and chemistry — are taught at the schools l)y special professors, aj^pointed for the })urpose from the university. The students also receive lectures upon religion on appointed days. A high grade of preliminary education is demand- ed of the students. The course is extended over four years. Three thousand silver rubles are at the disposal of the council for each school, as stipends for desirable students. The general censors are excellent and satisfactory, which give the student the diploma of doctor, but in case of extraordinary ability the council may give the diploma of magistrate of veterinary medicine. A foreigner may also obtain them by standing the same examination. The director also possesses the grade and rights of a dean of a university, while 296 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. the professors, docents, and prosectors rank with those of the uni- versities. The teachers are appointed by the council from can- didates who have distinguished themselves in scientific research, but must also demonstrate that they have the gifts necessary to becom- ing proficient teachers. The allowance for each veterinary institute, to pay the teachers, and other educational expenses, is yearly 35,700 silver rubles. To each institute is added a school for veterinary assistants, the course being three years, and is limited to practical in- struction by the teacher of horseshoeing, two clinical assistants, a pharmaceutical assistant, and special teachers appointed for the pur- pose. Organization of the Royal Veterinary College at Copenhagen^ Denmark!^ The Royal Danish Veterinary School was founded in 1773 by the talented veterinarian Alildgaard; it was again reorganized in 1858, and changed to a royal veterinary and agricultural high school, and removed to the suburbs of Copenhagen. By this ar- rangement, veterinary instruction can be directly carried out at one school, and in it are also taught agriculturists, surveyors, gardeners, and foresters, though the education of the latter is chiefly theo- retical. Owing to the number of departments or sections in the school, there is a better opportunity for more classes, and par- ticularly for special instruction of each class in its own branch of study. This school is under the control of the Minister of the Interior, and is presided over by a director, who does not teach, but who is a member of the Privy Council. The present director is Dr. C. E. Fenger. An agriculturist is also connected with the school as as- sociate director. The number of teachers is eighteen, ten of whom are appointed by the Government for duty only in the school ; the other eight belong, more or less, to the university, the polytechnic, and other schools. The assistants are in addition engaged in teaching the various sections, and there is also a pharmaceutist in the dispensary. The following are the branches taught the veterinary student : Anatomy, including dissection and physiology, by Dr. Bendz. Internal pathology and clinical instruction, by Professor Bagge. Chemistry and pharmacy, by Professor Barfaed. Exterior zoutechny, hygiene, and theoretic farriery, by Professor Prosch. * "Veterinary Journal," ii, p. 123. VETERINARY SCHOOLS OF BELUIUM, RUSSIA, SWEDEN, ETC. 297 Operative surgery, obstetrics, and surgical clinics, by Professor Stocktleth. Botany, by Professor Langs. Physics and meteorology, by Assistant Fjord. Zoology, by Professor Scliiodte. Veterinary jurisprudence, by Assistant Bay. Practical farriery, by Assistant Green. The avera-re number of students attendinf; the school since 1858 has been yearly about two hundred and fifty, being mostly veterina- ry and agricultural students. The students nnist provide their own maintenance and lodging. A free education and scholarship can be obtained if the student enters his name ; moreover, it is necessary that he has received a certain specified general education, which is considerably less than is required for matriculation at the univer- sity. Latin is not required. The scholastic year commences on the 23d of August, the annual period of instruction consisting of two sessions of six months each. Although the student is at liberty in the matter of attending lect- ures, yet the instruction is so arranged that these may occupy a pe- riod of six sessions ; as a rule, the period of study is four years if the following plan is pursued : First Session. — Physics and meteorology, six hours per week ; inorganic chemistry, four hours ditto ; zoology, four to six hours ditto ; shoeing practice, twelve hours ditto. Second Scs.fion. — Physics and meteorology, two to three hours per week for the first two months ; organic chemistry, three to four hours ; botany, two to five hours ; anatomy and physiology, five hours; zootechny, five hours; practical botany, one hour; practical farriery, twelve hours ; practical grooming, twelve hours a week for a month ; clinic, twelve hours per week. Third Session. — Botany, seven hours per week for a month; anatomy and physiology, five hours per week ; zootechny, four hours ; theoretic farriery, two hours ; pharmacy and pharmacology, two hours; pathology and therapeutics, three to four hours; sur- gery, three to four houi-s ; veterinary jurisprudence, two hours; practical botany, one hour per week for a month ; practical farriery, eight hours per week; dissection, exterior, one hour; clinic, twelve hours ; practical pharmacy, twelve hours. Fourth Session. — Anatomy and physiology, five hours weekly; zootecliny, five hours ; pathology and therapeutics, three to four hours ; surgery and obstetrics, three to four hours ; veterinary juris- prudence, two hours ; dissection, operative surgery, four hours ; 298 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. practical farriery, eight hours ; clinic, twelve hours ; practical phar- macy, twelve hours. Fifth Sessio7i. — Pathology and therapeutics, three to four hours weekly ; surgery, three to four hours ; dissection, operative surgery, four hours ; practical farriery, eight hours ; clinic and pharmacy, twelve hours each weekly. Sixth Session. — Ambulatory or visiting clinic ; veterinary juris- prudence. The veterinary examinations take place in April and October, and are divided into two parts : the first of these is in pure natural science only ; the second, in the other branches of veterinary medi- cine. Veterinary Medicine in Sweden.^ The first veterinary school in Sweden was founded by Hern- quist, born in 1726. After passing his examination as a doctor in philosophy at the University of Upsala, Hernquist went in 1T63 to France, and, more especially at Lyons, studied veterinary medicine. In 1774 he established the veterinary school of Skara, Sweden, and was designated professor of it in 1778, remaining in it until his death, 1808. He was a writer and practitioner of very high order. One of the best of his pupils, Korling, took his place in 1814 ; and in 1820, by order of the Swedish Government, he organized the veterinary school at Stockholm, remaining director of it, as well as that of Skara, until his death in 1855. The Skara school served as a preparatory one for that of Stockholm, where the student, after a stay of two or three years, underwent the examination for the de- gree of veterinary surgeon. At that time, as now, the students came from Sweden, Norway, and Finland, and during this period a great number of men belonging to each of these countries gradu- ated at the Stockholm school. In 1867 it was fixed by royal ordinance that before a student could enter that college he must have obtained the diploma of graduate in letters from the university. This excellent measure for the elevation of veterinary instruction was due to the initiative of Professor Landberg ; and, instead of diminishing the number of students, as some had predicted, it led to an increase. In requiring from candidates for admission to this school an amount of prepara- tory knowledge not demanded by any other veterinary school in Europe, the Swedish Government has taken care to protect the interests of its graduates and increase their income; the conse- quence is, that the number of graduates has correspondingly aug- * "Veterinary Journal," vol ix, p. 266, 1879. THE SCHOOLS OF GERMANY. 299 mented in quantity and quality. The candidate, twenty or twenty- one years of a^je, being a graduate in letters, is received into the veterinary school, and there he has to study for four or even six years. The school has four professors, each with an animal salary of about £230; a lecturer, with a salary of £108; an assistant, or ad- junct, and a teacher of farriery. Two of the professors, the assist- ant, and the instructor in farriery, reside at the college ; the others have a yearly lodging allowance of £28. The course of teaching at present is as follows : Anatomy, physiology, zoology, and pathological anatomy — Pro- fessor Kinnberg. 2iooteclmy, sanitary science and police, and the amlmlutory clinic — Professor Morell. Surgery, obstetrics, farriery, and clinical surgery — Professor Sjostedt. Pathology, therapeutics, epizootics, pharmaco-dynamics, pharma- cotechny, and special clinic — Professor Lindquist. Botany, physics, chemistry, pharmacology, and j)harmacy — Lec- turer Ericsson. The assistant aids in the clinic, and the other official instructs in the farriery. In Sweden there are thirty Government veterinary surgeons, who receive an annual allowance of £S0 and traveling expenses. The regiments in garrison have a regimental veterinary surgeon, with a yearly pay of £17»> ; and a battalion veterinary surgeon with the rank of sub-lieutenant, who receives annually £112. Regiments of the line have regimental and squadron veterinary surgeons, hav- ing the grade of non-connnissioned officers, and a pay of £56 yearly. The number of civil and military veterinary surgeons under the Government is 170, and all, so far as their technical duties arc con- ceniod, are under the direction of the medical authorities. TuE Schools of Germany. The School at Stuttgart* This school was the last established among the German schools. It was built on territory which had previously been occupied by the Zoological Garden, the royal order for its establishment being dated August 21, 1790. "Walz, Ilordt, and Ilaussmann were prominent * " Die Koniglich. Wiirtemberg. Thicrarznei-Schulc." Historically considered by He- ring. 1847. Rueff, 1871. 300 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. among the veterinarians of tlie state at this time, and were called upon to advise and take part in it. The former was bj far the most influential of the trio. He was born in Stuttgart, the 7th of De- cember, 1771, and died there, February 4, 1834. He received his first education in the gymnasium of his native city, and then in the Karls School of Philosophy, where he studied natural philosophy and the general j)rinciples of medicine, at the same time acquaint- ing himself with pharmacy in the shop of his father. Having se- lected veterinary medicine as his means of livelihood, he went to Vienna, for a time enjoying the teachings of Wolstein ; then visited the breeding establishments in Austria and Hungary ; thence his travels brought him to Dresden, where he tarried at the Veterinary School for a while ; then visiting the Universities of Jena, Erfurt, Leipsic, and Halle, and finally at Berlin, where he remained for nine months at the School of Veterinary Medicine. The reputation which the school at Copenhagen acquired under Abildgaard drew him to Denmark ; at the same time he studied medicine in the hospital of the city under Bang and "Winslow. After three years' absence he returned to Stuttgart by way of Hoya, Hanover, and Gottingen, and on the 9th of September, 1794, received the po- sition of an ofiicial veterinarian, having the supervision of the en- tire veterinary system of the dukedom. He soon became a member of the sanitary commission, and of many scientific and public associa- tions. "Walz was one of the first who asserted that the cheapest and best way to stamp out the rinderpest was to kill all diseased animals, as well as those exposed to infection. The invasion began in 1795, but so many difficulties presented themselves to the proper execu- tion of these principles that it was not until 1801 that the pest was finally got rid of, at a cost of some 40,000 cattle. His treatment of the scabies of sheep has become one of the fundamental elements of the veterinary practice. He took a most active part in advocating a governmental veterinary school, his efforts being finally rewarded by success ; his life was eminently successful, and he died respected by all and mourned by many. The conditions of admittance to the school were at first very easy, requiring applicants to be — 1. Twenty years old. 2. A healthy physique, with sufficient strength. 3. Free from military duty. 4. The necessary educational qualifications. 5. Of good moral character. 6. Must know some trade. TDE SCHOOLS OF GERMANY. 301 7. Must have means enougli to pay the expenses of their educa- tion. The school supplies sleeping apartments for quite a number of students, and residence for a number of the teachers. It is titted up with the auxiliaries to inf>truction, the same as other schools, but the collections of skeletons and specimens in the anatomical department are wonderfully large for so small an institute. The course of study was at tirst tixed at one year, many students, however, remaining over one, two, or even three sessions, themselves seeing the necessity of a more complete education. In this regard, it may be Avell re- marked that the tirst year in any medical school can do nothing more than introduce a student to his work ; and if, at the end of a four-years' course, he has progressed so far as to get a general view of the field before him, and has himself really learnetl how to study^ how to select the chatf from the wheat, he may consider himself as among the few who enter in at the strait gate which leadeth unto knowledge. All this talk about " completing an education,'' or '" he has a complete education," with reference to graduates from schools, simply shows the ignorance of the speaker ; for, as I have pre- viously said, it is only the Yirchows, the Franklins, the Darwins, and Ilallers among men who get so far as to obtain firm hold of the keys which are to unlock to them the treasury of knowledge in the future, but not without untiring work and uncea.sing self-sac- rifice, however. The rest never even get hold of the keys ; they are and always remain pettifoggers, dabblers, or mere routiners and fol- lowers in the path of the true lights which lead on to the j^erfcct day. The example of the students finally led to an increase of the term of study to two years, after a lapse of twenty-five years from the opening of the school. The school had at first four professors (a vast improvement over that at Hanover, which at first had but one, and for a long time but two) and a teacher of horseshoeing. The course begins every year on the IGtli of October and ends the 31st of August the following year. Vacations come at Christmas and Ea.ster, but such a number of students must always remain at the school as is requi- site to attend to the patients in the hospital. The library contains 2,1*28 books, and is open to the students under certain regulations, which are very easy to comply with : " They can keep a book out for four weeks at a time, and are allowed all books except such as are very rare or costly, which can only be used in the ruoms of the librars.'' 302 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. Patients treated hy the Students from 1821 to 1871. Horses : In the school hospital 18,091 Visited by students outside the school 5,896 Used for anatomy and operative practice ... 684 Asses and mules 45 24,716 Dogs : In school hospital 5,270 Brought in by police 755 6,025 Cattle : In school 270 Outside 16,794 17,064 Other animals 2,652 Autopsies 2,722 Whole number of animals treated in school for fifty years.. . 53,179 "Whole number of students in same period, 2,140. Of these, the following are recorded as having emigrated to America : L. Bickard, 1841-'42; Alois Ebach, 1865-'67; Will. Eberhardt, lS38-'39 ; J. F. Erpf, 1831-'32 ; A. Fritz, 1841-'42 ; B. Fusseneg- ger, 1844-'45 ; Aug. Gleich, studied winter of 1860 ; J. Haussler, 1840; G. Halm, 1842; L. D. Hess, 1824 ; Chr. Horz, 1849-'50 ; A. Ibach, 1886-68 ; G. F. Liitze, J. E. Mack, 1864-'65 ; J. Eitters, C. Shock, J. J. Schwarz, J. Stiefel, Chr. Troscher, C. E. Wolff. The school at Stuttgart is, I hope, soon to be among the " have beens." At one time it enjoyed quite an exalted reputation, but since the retirement of Dr. Hering, Sr., it has steadily been going into decline, and the students becoming fewer and fewer. This is in part owing to a very injurious stand adhered to by some of its teachers, and which was once quite general in Germany, viz., that a school should give two different forms of education, and graduate first and second class veterinarians — the first for the use of the state, the latter for the people. The nonsense of such an idea should be apparent to any one, but to no one so quickly as to a veterinarian. Of one hundred students graduating from a given class and a given school, and enjoying instruction uniting to the fullest possible de- gree a scientific foundation and practical execution, not all w^ill be successful practitioners, and but few suitable for state work, and still fewer for the highest state work — perhaps one of the hundred may make a really gifted and capable teacher. Let the education be as perfect as possible : the world's test will do the winnowing. It will not do to leave even this brief notice of this school with- THE SCHOOLS OF GEllMAXY. 303 out duly iioticiug the man who did more to ^ive it fame than, in all })rol)ability, all the othei-s c'ond)iued who have taught withiu its walls. About the thirtieth year of this century really marks the birth of the scientific tendency in veterinary medicine. At this time (Germany was far beyond any other country in the quality of the work she was giving to the world, so far as veterinary medicine was concerned. Gurlt, llaubner, Ilertwig, and Ilcring were the four, among others, who took part in this work. Of these four, Eduard Ilering was by no means the least. He was born in Stutt- gart on the 2ortant matters and articles which came to pass in connection with their profession in other lands. His ''Special Pa- thology and Therapeutics," and his " Book for norsemen," are still well worthy of study ; the latter is beautifully illustrated by the celebrated Baumeister, also professor at the school, and is bought up so closely as a work of real art that it is impossible to get a copy, it being out of print for many years. His work on opei'ative sur- gery should be translated into English, it being much more j)ractical and condensed than the two-volume verbose and indistinct work of Pcuch and Toussaint ; a compendium, critically revised, would be a grand thing, but deliver us from the original 1 But the one act which has given Ilering the most fame, the one act which did more for the elevation of veterinary medicine into a science than all the work of all the other jirofessors at the school, the one act which has made his name immortal as a discoverer of a new fact, was that Ilering was the first to ex])crimentally demon- strate the velocity of the circulation in the living organism, pul> lished in " Tiedemann und Trevirarnus Zeitschrift fiir Physiolo- gic," Heidelberg, 1828. 304 THE ESTABLISHMENT OF THE YETEEIXART SCHOOLS. The School at Hanover.^ On the 15tli of April, 1777, the first steps toward the erection of a yeterinary school were taken into consideration by the king, or rather elector, who was at the same time George III of England, and Kersting, the superior veterinarian of the court at Cassel, a neighboring province, was invited to visit Hanover to advise about the opening of the school, and take charge of it. Kersting's popu- larity was so great at the court of Cassel that he could not obtain permission to leave for Hanover, and was obliged to run away. As Kersting was by all means the most important German veterinarian of his day, a short sketch of his life is not out of place here : " Johann Adam Kersting was the descendant of a Huguenot family, and was born at Liebenau, in Lower Hesse, in 1726, and died at Hanover, March 2, 1784, from the effects of a wound caused by the kick of a horse, at a time when he could ill be spared, being but fifty-eight years old, and full of bodily vigor and mental activity. His father was a farrier, wound-doctor, and veterinarian. At fifteen years of age the son went into the forge of his father at Cassel, where he soon displayed unusual abilities. Among others, he be- came acquainted with a clock-maker, and took so much interest in the work of the latter that he himself constructed a clock and hung it up in his fathei-'s forge, which so incited the wrath of the latter that he knocked it in pieces, declaring he would have no such non- sense interfering with the proper work of his son. The son also busied himseK in studying the diseases of the horse, and practicing their treatment ; and we find him, in 1745, as farrier accompanying a squadron of Hessians into Scotland in favor of the Stuarts. He accompanied the Hessian prince of the day during several wars as farrier, and at the close of the Seven Years' War studied medicine in Gottingen for a time. During the war in Silesia (1757) he was thrown from a baggage-wagon, with such force as to lose both sight and hearing, the former not returning for a period of two years. During his blindness he attended to the publication of the first edi- tion of his book, " Sicherer und wohlerfahrener Huf und Eeit- schmidt " (" Sure.and Well-experienced Farrier and Rider"). Dur- ing a winter's quarters at Brunswick he again studied medicine diligently. At the end of the war he settled at Cassel, as farrier veterinarian to the court, where he busily pursued his studies, espe- * These remarks are taken from " Die konigliche Thierarznei-Sclmle zu Hannover," during the first hundred years of its existence, by K. Giinther, director and professor, to which the reader is referred for all minute details. THE &CHOOI.S OF GERMANY. 305 cially of anatomy, and soon acquired a rej)utation wliieh extended into neighboring provinces. That he acquired no inconsiderable skill ill anatomical dissection may be divined from the fact that he discovered ami very minutely described the mendjrane of Deccmet in the horse, on the inner part of the cornea, and connnunicated the same to Ilaller in a letter vehich is among the collections at the Han- over school. lie soon received students from the adjoining prov- inces, other governments sending young men to study under his guidance at their expense. It was but natural that, on opening the discussion for the erection of a veterinary school at Hanover, the attention of the Government should be directed to him as the man best fitted to successfully conduct the venture. Ivei*sting's sudden departure for Hanover, against the will of his elector, gave rise to a most interesting discussion between the two Governments, that of Cassel declaring him to be a deserter, and demanding his return, which was not, however, conceded, Kersting declaring himself to be no slave but a free man, and in debt to no one. Kersting was a man of irreproachable character and lively temperament, an in- defatigable worker, sharp and logical thinker, and close observ'er of the phenomena of disease. In this regard, a remark which he makes upon glanders is not without public interest, when we con- sider how long ago it was made, and how ignorant many people still are with reference to this disease, thinking that when no nas;il out- flow and ulcere are present there is no glanders. Kersting says, after giving the usual characteristics of the disease: 'I must concede, and it is true, that a glandered horse can present these phenomena, but not in the beginning of the disease. For a horse may have glanders for a whole year, and, according to circumstances, still longer, without its having ulcers in the nose, and at the same time have a good appetite, smooth hair, and be in good condition.' " Kersting received 300 thalere (8-25) pay, a free residence, and the title of superior veterinarian to the Hanoverian court. Ilavemann, who had been sent to Alfort, at the expense of and by the Government, was appointed as assistant teacher, at the same pay. There seems to have been an extreme prejudice existing among the people at this time against those persons who had any- thing to d<; witli cutting up animals, for the king was obliged to issue a royal order, by which any slurs or other ill-treatment of the teachers, students, or servants at the school for this cause would be punished. The course at the school under Kersting was limited to one year, though many of the students remained through two, hear- ing the same lectures a second time. It was as follows : 20 306 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. WiNTEE SESSiOiSr. Befove noon. — 8 to 9, horseshoeing, dailj ; 9 to 10, instruction npon the internal and external diseases of the horse, four days each week ; 10 to 11, clinic. Afternoon. — 1 to 2, dissection, daily ; 2 to 3, anatomical lec- ture, four days per week. General examination upon all subjects twice weekly ; 3 to 4, dissection. SuiMMER Session. Before noon. — 8 to 9, horseshoeing, daily ; 9 to 10, internal and external diseases, daily ; 10 to 11, clinic. Afternoon. — 2 to 3, osteology, exterior, physiology, hygiene, obstetrics, materia medica, pharmacy, bandaging, etc, one day each per week. On Kersting's death, the direction of the school passed to Have- mann, who had for a time been stationed at one of the royal studs, which he left with great regret. He was a man of extreme mod- esty, but nevertheless proved himself to be a competent and pleas- ant teacher. There was but little change in the course or manner of instruction. Havemann was requested to give his views upon veterinary education to the Government ; and this man of the last century embodies some ideas therein which are not unworthy of ap- preciation in this country, which, to-day, in spite of self-conceited Americanism, is no further advanced, so far as veterinary science is concerned, than Hanover was then : " According to my ideas, tiet- erinary medicine would receive a much more rapid development if the education were made entirely free to the children of the land, as there are so few veterinarians to he had. Applicants must not only be able to write legibly, but must give reason to hope for their fu- ture success by diligence and a natural adaptability to the profession. Those who have not these two necessary qualifications must be dis- missed the schools, for, while it is an undoubted truth that capable veterinarians are of much benefit to the public, so is it beyond all doubt that empirics and quacks are nothing else than lashes to the land, even though they be supplied with letters of apprenticeship, saying that they have studied in a royal veterinary school an art of which they have not acquired the least idea," In answer to the question, "How long would it take a gifted and industrious man to become an educated veterinarian % " he says, " One learns quicker, another slower, but to all are necessary great capability, much work, and these all demand time, and three years are none too little." But, in spite of all this good advice, the course was not much extended by the Government, or the conditions to admittance made much more severe. Hausemann succeeded Havemann as director in 1819, and had THE SCHOOLS OF GERMANY. 307 for assistant the veterinarian Freilerick Giinther. Little change was made in the ])hin of instruction until 182S, except that the courses were made longer. In 1828 Gunther introduced into the curriculum forensic medicine and veterinary j)olice, materia medica, and the art of writing and nuiking prescriptions, with several other essential im- provements. A teacher for horseshoeing was also added to the school. The period of study was extended to two and a half years, although Giinther worked earnestly to have it three yeare. In 1847 Gunther became director, and with it began a new era in the school. There is no doubt that he was one of the most eminently practical men that has ever graced the veterinary profession in any country ; per- haps it would not be going too far to say that the scientific and practical were united in him to a degree which has been but rarely met with in the members of our profession. lie was an earnest ex- perimenter, a close observer, and his greatest failure seems to have been too much delay in publishing his results. No better hippo-anat- omist has ever lived ; his work on the " Myology of the Iloree " has never been equaled, and has been a source of assistance to all succeed- ing authors. He was the tirst to discover the chief cause of roaring, if not the only one, in atrophy of the laryngeal muscles, upon which opening of the glottis depends, especially of the left side, and con- nected it by experiment with diseased conditions of the left recur- rent nerve. lie gave us the first book of any moment upon the horse's teeth and their diseases, and invented numerous practical (not useless) instruments for their extraction, etc. Xo one has fol- lowed him in this direction, atul we remain just where he left us in the middle of this century. His work on obstetrics was for a long time the best which we had. Through his earnest endeavors and untiring energy, the school-term wa-s finally fixed at three years, at which it continued until 1877, when with all the German schools it was extended to three and a half, and the conditions to admission and receiving the diploma of the empire were fixed alike for all. Gerlach succeeded Gunther as director, and under him the school attained a still greater celebrity, but, as we have to speak of him in e()nnection with the school at Berlin, we will defer further remark till then. The grounds of the Hanover school are quite extensive, the library replete with books and many valuable manu- scripts and works of early German and other Continental veterinarians. The buildings are many of them new, and all have recently suffered renovation. The hospital is roomy, airy, and well lighted ; in fact, the school has all the requisites necessary to such an institution of a smaller variety, except a special physiologist and physiological 308 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. laboratory. The above-mentioned historical sketch, from which I have taken these few facts, gives a list of all the students, their place of birth, time of entrance, and whether they received a diplo- ma or not, from the year 1820 to 1877 ; from which we see that during that time 1,269 students were recorded upon the books : many of these never stood their examination ; among the latter will be found, in all probability, quite a number of " graduates of a German school " (?) now practicing in this country. The present corps of teachers is as follows (1877) : Medical Councilors. — K. Guenther, Director ; Professor Bege- mann. Professor Dr. Dammaun, Dr. Harms, Dr. Lustig, Dr. Rabe, Dr. Brlicher, Dr. Eichbaum, Vet. Ernst (assistant). The School at Munich. Instead of offering an imperfect historical sketch of this institu- tion, it seems more conformable with the purposes of this book to offer to your consideration a translation of the following address, " U])on the Necessity for the Reform of Yeterinary Education in Ger- many, as proved hy the History of the Munich School,^^ by my friend Professor Johann Feser, of that institution, delivered August 6, 1873 ; the more so as there is much contained therein of unquestion- able importance to the people of this country, and further, that the author is one of the most advanced thinkers as well as accomplished scientists in the veterinary profession of our day : " The veterinary schools have assumed no less a task than the education of completely qualified veterinarians, for their graduates have a manifold service to perform to states interested in the breeding of domestic animals, which can only be well done by a complete scientific and practical education, united to great diligence and unceasing activity by the veterinarian himself. " The veterinarian must not only be capable of performing the practical duties of his profession when called upon by the public, but he has much higher duties; he must at the same time act as counselor and protector of the state, and that portion of its citizens interested in the breeding and rearing of domestic animals, thereby contributing to the nation's welfare by keeping distant and suppress- ing those pests which carry death and desolation in their path. " The chief task of the veterinarian lies in keeping the domestic animals in health, and in exerting a favorable influence toward their perfection hy aiding, as educated advisers, the progressive de- velopment of breeding in the land {to which may well be added, and in 'preventing many diseases of human beings caused by unsuitable THE SCHOOLS OK GERMAXY. 309 animal jyroducfs \chich would otherwise he offered for consumption as articles of food). The veterinary schools are 7wt, therefore, founded for tfie education of mere curers ; they are not instituted to send raw empirics into the land, for in such cases the aims of veterinary medicine are by no means attained. Sucli empirics were plenty enough long before the foundation of the veterinary schools ; and only because of their utter uselessness to the state were the veterinary schools founded, in order that veterinarians could be had suitable to the higher purposes which the public necessities de- manded. " In order to prove the correctness of this assertion, it is neces- sary to refer to the history of the veterinary schools. We must know why these schools were really founded, what necessity they were expected to fill, and how observing men thought this end was best to be attained. "To this purpose nothing serves better than the address deliv- ered by Cothenius, body-surgeon to Frederick the Great of Pnissia, before the Academy of Sciences on the 21st of January, 17C8, be- fore there was any veterinary school in Germany. Cothenius first demonstrated from the records of history that in antiquity, and fol- lowing down to his time, devastating animal plagues had always ex- isted, which produced immense misery to the people, and concluded with the advice that only veterinary schools had the power to give the means of freeing the nation from these plagues ; but he placed great emphasis upon the necessity of an exact fundamental educa- tion, giving a plan for their establishment which is well worthy our present consideration, though elucidated over one hundred years since. lie knew very well that at that time there was no thor- ough plan of education, no veterinary science, and no teachers, and that for the last purpose men of great ability were necessary, for they were to teach subjects of which they knew nothing, and upon which there were no suitable books of reference, or other assist- ance, lie said: 'The first teachers must not be ashamed to be themselves students ; their greatest honor must be the public admis- sion of their own ignorance. The less they at present know, and the more they feel the necessity of learning, the more have we rea- son to hope that they will in time attain to that degree of perfection which thov so much desire.' Thus we see that Cothenius well a|v prcciated the only way by which veterinary science was to be suc- cessfully developed. He looked upon this task from a purely scien- tific stand-point, and well knew that progress was only to be at- tained bv the methods and assistance of scientific research. To 310 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. this end he demanded not only macroscopic but microscopic anat- omy, a physio-pathologic, therapeutic method of exact investigation, and recognized the necessity of a well-ordered chemical labora- tory. He laid emphasis upon the necessity of several teachers for such schools. He recommended paying especial attention to the study of the animal plagues, and laid great stress upon the value of exact observation and experiment. He says : ' In the study- room one can make no such observations. The teacher must, at the time such pests prevail, go out into the country, and hold his dietetic, pathologic, and therapeutic discussion in the afflicted sta- bles ; he must observe the situation and character of the stables, and cause better ventilation, cleanliness, and care of the animals ; he must visit the fields, meadows, and drinking-places, in order to ascertain if in them are not to be sought cither immediate or mediate causes of infection, and what in every case is necessary to propose for the better protection of the animals. He must gather all forms of dew, and make therewith chemical and physiological experi- ments, and must also have recourse to the microscope in order to see if he can not discover some poisonous insects, which, either of them- selves or with their semen, so pollute the vegetation as to cause the generation of the pest or other infectious disease.' (In reading this one almost forgets he is passing over words written more than one hundred years since.) ' The teacher shall study the animal in all its parts, its mode of life, procreation ; and, when necessary, shall have recourse to the crucible and distillation to increase his knowl- edge. He must separate things into their minute parts, unite and make new bodies, and seek to attain a sort of despotic power over nature.' " This is what was thought in the last century by the founder of veterinary medicine in Germany. The schools Tnust he useful nurs- eries of science^ and not produce mere empirics. Let us see if the schools have fulfilled their task, and, if not, seek to discover what has prevented them from doing so. It is all the more our duty to do this, as the popular judgment with regard to the results at the schools seems to be at present un- favorable. Kot only the organs of the state and agriculture, the interests of which are to be served by the educated veterinarian from an economical point of view, but also the graduates of the schools, concur, more or less, in this opinion, as was sufficiently demonstrated at the Frankfort congress of German veterinarians in 1872. It is especially the duty of the teachers at the schools to acknowl- THE SCHOOLS OF GERMANY. 311 edge tlicse evils, aiul to seek fur their removal, and I doubt not that the governments will respectfully listen to our demands for reform. 1 pledge myself to Lave the strictest regard for the truth in the t;isk I have undertaken, even though it may be unpleasant to some, and to bind njyself to facts ; and, in proving the questions we have to consider, to do it according to the strictest methods of science, and to keep in mind only the attainable and practical parts of the ques- tion. With reference to the history of the Munich school, we shall most speedily atain our end if we consider those causes which have, at dillerent times, interfered with the production of good veterina- rians. Then I will show that even in our day evil conditions still exist, the complete removal of which is beyond the power of the best teachers, notwithstanding all diligence and pei*severancc. The proposals for improvement will then receive their consideration. The school at Munich has passed through two epochs since its foundation. The tirst extends from its establishment in 1790 to the year 1S52, and the second from that date to the end of the school year 1872. Nothing satisfactory can be said about the condition and results at our school during the first epoch. Empiricism obtained a greatly extended duration in Bavaria, while at the other veterinary schools (German) it extended only to the second decennium of our century. Many of the learned gentlemen present studied at our school during this period and must confirm my judgment, that our institute had until then never filled the place of a scientific veterinary school as portrayed by Cothenius. Xothing but schooled " routiniei-s " were produced, nor did they dare to produce anything else. They hid themselves under a deceptive cloud, by boasting of their abhorrence of speculative theories and of their great respect for practical things, which by no means should be neglected, but by this means they nour- ished an imbecile empiricism and sought to keep distant from all true science. It was made exceedingly difficult for young men of better preparatory education to gain entrance to the school ; in fact, they ap- pear to have been intentionally avoided, so that any external incite- ment to scientific work became impossible. The experimental method suggested by Cothenius as absolutely necessary to the sch(X)ls had no ])lace in the programme. The great reforms in medicine in general, and every natural science, were passed heed- lessly by, by the Munich school of that period. Instruction in natu- ral sciences, the foundation of the study of medicine, was so neg- lected that one feels almost ashamed to mention it. The few stu- 312 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. dents who gained admittance from the " real schools " were aston- ished thereby, and scorned to make notes upon the nonsense which they heard from the lecturer at the desks of the school. There was neither chemical laboratory nor physical cabinet, but every "real school " had these long before 1852, and all the attributes necessary to good elementary instruction in natural science. Let it remain so ! We will not follow this sad relation further. You will believe me, however, that with the exception of anatomy, the conditions were no more flattering with reference to the purely veterinary branches than with the natural sciences upon which they are founded. One would naturally assume that, although the scien- tific side of our education was so much neglected, the students at least received a good practical education. On the contrary, that was not the case. Let us see if we can not discover the causes of this neglect of the teachings of Cothenius, To this end we must again have reference to the general history of the schools, and bear in mind the extravagances of the first French schools, to which many evil influences may be justly attributed. Two schools (Lyons and Alfort) were organized in France some years before the foundation of any in Germany. The Alfort school was larger than that at Lyons, and received from the beginning great attention and care from the Government. The fittings of the school exceeded those of the German schools, even in our day, and every condition was present to attain the ends which should be re- quired of a school except fitting teachers and promoting veterinary science. Suitcible teachers are and ever will he the chief desidera- tum / without them all donations of money are useless. This was soon experienced by the French schools. Instead of proceeding in the manner indicated by Cothenius, and first paying their attention to the development of proper teachers, they sought at once to make the world wise by a display of superficial knowledge. The students were educpted in a manner to produce superficial but ready talkers, but not to become methodical and educated veterinarians. The Al- fort school especially sought to gain an acknowledgment of supe- riority from other nations, which was, indeed, attained, but not with- out great injury to herself. Chairs for agriculture, comparative anatomy, natural sciences, animal painting, etc., were even then attained, although the raw empirical material at command had by no means been sufficiently culled out. The students must at once be educated to be obstetricians, wound and eye doctors, coroners, etc., in order to fill the wants of the country in this regard. They THE SCHOOLS OF GERMANY. 313 founded a menagerie filled mostly -with exotic animals, and gave great attention to the breeding of sheep, rabbits, fowls, and even silk- worms. To the formation of the so-called ''royal cabinet," stu- dents and teachers were sent at great expense to the sea-coast to •rather examiiles of different sea-animals. Thev studied the anato- my of the dolphin and ray, and forgot that of the domestic animals. This superficial learning of a little of many things was especially cul- tivated by Bourgelat to the cost of a true scientitic method, and found, fortunately, little imitation in Germany. But instead of pass- ing quietly by these French extravagances, and copying them in what good things they had, we fell into the opposite extreme of developing one-sided empirics, the so-called " Rossiirzte " (horse-doc- tors) and " Kursehmiede " (farriers). Every attempt of individual men at the schools to introduce the true scientific method was ener- getically combated, and the French schools quoted to strengthen the ground of the opponents. Bojanus, medical councilor in Hesse, enjoys the nnenviable reputation of having most successfully op- posed all improvement. I can not refrain from telling you how Bojanus would have the veterinarians educated and the schools con- ducted, lie had a controlling power at the Munich school until 1S52. Bojanus looked upon the education of i'>ractlcal men as the sole task of the schools. They would fail of our purpose were they edu- cated to be scientific veterinarians. (The English have most reli- giously followed in this direction even to our day, and here in Amer- ica a good practical ignoramus is in general more prized tlian the man of genuine scientific attainments ; let it be understood, I claim, a trnhj scientific man can never be aught else than practical.) Cer- tain axioms were to be learned as articles of jiractical belief, the students being reduced to mere mechanical machines. The state needed only veterinary hand-workers (in some parts of France the veterinarians are still spoken of as '* artistes vi'terinaires "), who would follow the rules learned at school with blind confidence. Such a practitioner never asks the cause of the phenomena which he sees presented to him by a diseased organism ; he does not seek to enter into the real nature of the disease, but is contented to know that dis- ease is before him. He does not seek to arrange a special method of treatment, but u.ses that which he has learned as something dis- covered for all time. lie is all content when the patient recovers, and asks not why, nor under what neccsi?ary laws, it lias taken place, lie enters pul)lic life as a common artisan, and must always be classed as such ; he never feels the power in him that is given to 314 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. the scientifically educated man, but is content with the bounds and bars which surround him. The school was to take only such stu- dents from the masses as were fitted to go back again to the same. Their knowledge was to be limited to what was necessary to their livelihood, and to read and write sufficient to support the memory. 1^0 other preliminary knowledge was considered necessary. They were entirely wanting in a preparatory scientific education or spirit. You will permit me to describe to you the method of instruction which Bojanus would have introduced into the schools, especially as two teachers of modern times (Director E,ueff, of Stuttgart, and Professor Plug, of Giessen) would have us follow in the same di- rection. Bojanus writes: "It is the duty of the practical veterinarian to cure the sick animals belonging to the public. His office, which does not belong to the most respected, brings him constantly in relation with the commonest people, to whose ideas and conceptions he must adapt himself if he will not endanger his success and let it pass over into the hands of quacks and herdsmen. He busies him- self with disgusting work in dirty stables, and all his endeavors and privations are rewarded with but a scanty income which scarcely covers his necessities, and, at the most, permits him to enter society as an ordinary artisan." Bojanus then goes on to say that "the scientifically educated veterinarian is unsuited to such work, and could not lower himself to the necessary level, and is therefore never looked upon by the people as a j?raciical man, and, there- fore, it is the duty of the schools to educate practical, not scientific, veterinarians." These words of Bojanus justify us in concluding that he knew right well the qualifications of a scientific veterina- rian, but he intentionally put all he could in the way of their edu- cation. On the contrary, Bojanus would have the teachers scientific men in order that they might discover new methods of treatment and give them to the students, who were supposed to follow im- plicitly in these ruts in practice. To the end that the state may have such teachers, Bojanus would have another form of school, a higher, scientific school. In these were to be taken the candidates for teachers' positions, with a complete scientific education from the lap of the academy. Bojanus either did not see, or passed in- tsntionally by, the fact that the state needs scientifically educated veterinarians for the purposes of veterinary police and forensic medicine, and for the perfection of the breeds of the domestic animals. The second class of veterinarians were there only to be curers, and a very small class of scientific veterinarians to develop THE SCHOOLS OF GERMANY. 315 ciire-methods for the benefit of the former. In this way there came to pass the idea that two chisses of veterinary schools were necessary, which occasionally finds an advocate even in onr day, althongh it must be remarked that these people go higher in their demands for a veterinary academy, and propose that not only teachers but a small number of scientific veterinarians also shall be educated for the ])ur- poses of the state. If we return to the conditions in Bavaria, we shall iind that only the poorest proposals of Bojanus came to fulfillment, and that no one bothered himself about the education of scientific veterinari- ans. According to the edict of 1810 for the organization of the veterinary institutes of Bavaria, that only went out of power in the last few ycare, it was found very convenient (at first, doubtless, ne- cessary) to promote the forensic M. D.'s to veterinarians of the first class, falsely assuming that the doctor, from his education, was well adapted to be the highest veterinary authority, and that a short visit to the lectures at a veterinary school would completely equalize any want of knowledge he previously might have. The lectures for this purpose in Munich lasted eight days. In two or three hours were completed the lectures upon nutrition in the horse and rumi- nants ; in one hour those upon operative surgery ; and in one to five hours the elements of animal pests, or veterinary police ; one to three hours were given to gaining practical knowledge in the clinic. Only an idiot could assert that this kind of education would sufiiee to the production of scientific veterinarians, for even in 1790 the full course of stuily for second-class veterinarians at Munich extended over three full years. The above description suftieiently indicates the hindrances in the way to the education of scientific veterinarians in the first epoch of our school, and no one need wonder that our science stood still impotent in comparison to human medicine and that it could not develop to that position which it was expected would be the case with the foundation of the schools. Notwithstanding the diflicul- ties which they had to overcome, it must be said, to the credit of the profession, that even during tliis period many men of acknowl- edged ability were to be found in the land ; but it is impossible to place this to the credit of the school, but to the great diligence of the individuals, who overcame the failures of their school educa- tion. A not less praiseworthy service of these men was the fact that they mercilessly exposed the weakness of the school, and finally succeeded in bringing about the reform which took place in 1852. After the Government of Bavaria had seen the failures in the 316 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. manner in whicli the scliool was conducted, and after it had re- peatedly heard the grumblings of the agriculturists that mere em- pirics were useless, a reform was decided upon, which, however, failed of a scientific basis. The germ of the failure was that the school still remained patterned after those of France, and was left free from every connection with the medical faculty. It was as- sumed that all scientific foundation in the preliminary education was unnecessary, save what little was gained by students in a low class of a " real " school, and the two lowest classes in Latin. The teachers were too few, and, taken mostly from the old empirical school, were not adequate to the education of veterinarians suitable to the purposes of the state. Tliey were so poorly paid that they were obliged to have outside occupations in order to live, so that teaching and self-improvement became a matter of secondary im- portance. " I myself had the misfortune to study three years (1857-60) un- der this Tcglme. The conditions at the school then were sad indeed, for I will describe to you a time when we should have seen some- thing of the development of the scientific spirit. The school did not then have the least scientific character ; even the good of the old school, the instruction in anatomy and dissection, was neglected. The physiology which we heard was nothing else than what Schwab had written many years before for the instruction of empirics. Kot a single experiment illustrated the lectures. There was no practice in the use of the microscope. The instruction in natural science, over which so much talk was made, consisted in nothing else than in learning by rote a few pages of j)Oorly compiled chemical analyses from Gorup-Besanez's work upon that subject. There was a chemi- cal laboratory which had just been erected, but only for the agi-i- cultural experiment station, and exclusively for the use of students of agriculture and forestry from the university. The instruction in botany was very poor. Physics was not taught. The formulas for the prepan.tion of medicines passed as traditions from student to student, and I do not say too much in stating that not a single one was con'ect. Pharmaceutical chemistry was lectured upon by an as- sistant, but a second one coming after one lecture had been deliv- ered, we did not attend them further, for we knew more chemistry than he did. The pharmacognostical collection was poor, old, moldy, and unsuitable for study or demonstration. The teaching upon the action of medicines was nothing more than a mere phraseology, which served to hide the ignorance of the teacher, but did not help to instruct the students. The balance of the instruction bore the TUE SCHOOLS OF GERMANY. 317 same character. The dependency and insufficiency of tlie institute is well illustrated by one fact, which amply shows the requirements which were necessary. In order to make a correct necroscopical diagnosis, for instance, of liright's condition of the kidneys, it was necessary to call in the assistance of a professor of pathological anat- omy from the medical faculty of the university, and numerous valu- able and instructive specimens sent to the school by practicing vet- erinarians perished for want of proper aj)preciatiou. It is no wonder that the congress of veterinarians atAViirzburg, in ISGO, pronounced it a w;iste of time, trouble, and money, to allow the institute to con- tinue its existence. I will cease, at this point, enumerating the sins of the Munich school during the first half of this epoch, as it would not be courteous to extend it to the present teachers." Let us turn our attention for a moment to the other schools of Germany, for I have endeavored to get at the true facts, so far as was in my power. With the exception of Berlin, which, notwith- standing a brilliant external reputation, had fallen into a stiige of semi-torpidity, its teachej's having become old, and new power being needed, and the school at Stuttgart, the schools at Dresden and Hanover were in many instances worthy of being considered as models. Dresden had suffered a complete renovation, and Gerlach worked in Hanover. (In both these cases it was, however, the work of single individuals which gave these schools what little advantage they had. Ilaubner in Dresden, and, as Feser says, Gerlach in Han- over; there was nothing general about it.) But neither of them went beyond the education of clever empirics — in proof of which may be noted the fact that, after the reformation of the plan of the Dresden school, of which so much was spoken and expected, it was found impossible to find veterinarians suitable for teachers, and the chairs were only finally filled by going outside of Saxony, and at great expense. (Here is a proper place for me to remark that, not- withstanding the high position which I have clainu;d for the Ger- man schools and other veterinary institutions, no one unacfpiainted with the true conditions can realize how few men there are among the graduates of the German veterinary schools at all fitted to be- come teachers, and every one of these few, and every man who has gained fame before them, have been obliged, at great cost to their physiipie and demands upon means which in no case are too plenty, to fill the great gaps in their ctly col- lected by him, and mounted under his supervision ; this number has been steadily increasing under his able successor in ])athology. Professor Schutz, so that, although I have not the catalogue number, there must be at present in the museum some eight to ten thousand specimens. His collection of fetal specimens, illustrating their peri- odical development, is one of the ornaments of the school. In 1823 another M. D., Ilcrtwig, was attached to the school after studying veterinary medicine at the most prominent institu- tions of the world at the expense of the Government. It was these two men who raised this school to the high defjree of renown which it enjoyed up to about 1850. Ilertwig has been one of the greatest contributors to veterinary literature that has ever lived ; he is a con. temporary of Ilering, Ilaubner, and, of couree, Gurlt, who with Spinola, as practical author, served to make the German name so famous in the middle of this century. His studies of rabies, sup- ported by numerous experiments, opened a new light upon the sub- ject, and have never been much improved upon ; these, with other contributions to canine pathology, in unison with those of Gcrlach and Fiirstenberg, have served to make up about all there is, or has been written upon the diseases of the dog, other than a few practi- cal hints gained from experience. Ilis work on nuitcria medica was not excelled by any in human medicine in its day, and is founded largely on personal experiments. His surgery and work on operations are by no means antiquated. As the ycai-s increased with these men, the school slowly pa.'jsed into decline ; its wonted activity was no more, but no want is felt long in this world before the right man is found to fill it. Ix'isering most beautifully jiictures this con- dition in his obituary notice of Gerlach, who was called from Han- over to fill this place : '' Slower and slower went the machine, which was chietly to be sought in the increasing years of her once active men, who were no more able to keep pace with the rapid march of science, and who also nourished the opinion that new things are not always the best. But the machine moved again with new fire, partly with permanent and partly with transient powers. 324 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. for as well-organized a body as the Berlin school had been since Langermann's time does not so easily come to a complete stand-still ; but that such an evil condition should not really occur a new fire- man was necessary — and he came. He made fresh fire, and we soon saw the glistening sparks." As Gerlach was, in my opinion, the most important character, the most original genius that has ever appeared on the German veterinary arena, if not of the world, I may be pardoned a short sketch of his life. I do this the more willingly, as the memory of this man still waits due appreciation in his native land, probably because of the intense severity with which he sought to instill into drones the grand fire by which he himself was impelled to sacrifice life, health, and friendship for the good of his profession and country. Andreas Christian Gerlach was born at Wedderstedt, in the Harz Mountains, the 15th of May, 1811. His parents were honest peasants, but had little means. His early education was received at the hands of some childless relations who resided near Halberstadt, who soon learned to love the pale, earnest boy as their own child. The child saw one day an old veterinarian in the village busied about some animals, which greatly excited his interest. He fol- lowed the old man from stable to stable, from patient to patient, and only returned late at night to the friends who had adopted him. This childhood's experience seems to have determined his future destiny. After his confirmation, his adopted parents sent him to Halberstadt to school, without, however, having sufiicient means to cover his expenses. Here began a time which indeed proved the stuS the boy was made of, and which developed in him that char- acter which drew little love toward the man in later years, but which enabled him to overcome obstacles and trample under foot an opposition as bitter as any man ever had to combat. He had first to prepare for his entrance into the gymnasium, and lived in the family of a poor artisan, who kindly gave him food. He sought with great perseverance the company of students in the higher classes, hoping to improve his knowledge thereby. Leisering, from whom the above remarks are taken, says : " A doctor, with whom he is acquainted, who lived at Halberstadt at this time, told him some years back, after Gerlach had already become a noted man, that it was not without much feeling that he recollected how the boy Gerlach had come to him in his peasant clothing and begged, with his eyes filled with tears, that he would give him free instruction in Latin. . . . He finally completed his school-days at Halberstadt, after enduring untold hardships and a continued battle for the food THE VETERINARY INSTITUTIONS OF PRUSSIA. 305 necessary to support life; but he had attained his end, and acquired the necessary kno\vledy;e fur admittance to a veterinary school.'' He gained this knowledge at great cost, and therefore highly ap- preciated diligence in others, lie was ever an advocate of higher education for veterinarians ; ever on the side which tended to the advancement of his profession ; from first to last he was a scientist and a student. He graduated from Berlin in 1S33, and until lS-1-4 practiced his profession at the i)lace of his nativity in Saxony, lie there published a pamphlet upon " Anthrax in Sheep," which soon attracted the attention of the Government, and led to his being called to Berlin, first as assistant and then as teacher. In lb5*J he received the honorable appointment of Director of the Veterinary School at Hanover, which he came near losing, however, as he placed as absolute condition to his acceptance that he should have the title of " professor,'' which had never before been given to a veterinarian, and which in Xorth Germany does not mean, as it does in these glorious and free United States of America, anything from a genuine man of genius at a university down to a shoeblack, dealer in old clothes, or vender of (|uack medicines. Ilis promotion to professor was soon followed by that to privy medical councilor. " He was in Prussia not alone the first veterinarian who received the direction of the veterinary school (previously it had always been given to medical men of note), but also the first veterinarian who, without being also an M. D., received the titles ' medical ' and * privy medical councilor,' " Between 1859 and ISTO were made the greater part of those original researches, which have gained accept- ance not only in veterinary but human medicine. He was the first to obstinately deny the abiogenesis (self-develojnnent) of glanders. To his investigations is also owing the excitement with reference to the transmissibility to human beings of the tuberculosis of cattle. To the extreme obstinacy with which he defended these opinions is due much of the opposition which he received from the profes- sion. In 1870 he became director of the school at Berlin, and began, or rather went on, developing the work of his life — the further intro- duction of the scientific method into veterinary instruction. So far as the future of the profession in Germany is concenied, I think that Gerlach's last act was l>y far his greatest — that is, the introduction of a specialist as physiologist to the school, and the erection of a proper laboratory and experiment station. I myself lived through this, and no one better knows the bitter opposition which conserva- tism and selfishness put in the way of the purposes of this man, whose only desire was to improve the school and serve well his country. 326 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. Gerlacli was said to be a verj one-sided man by those who felt the power of his opposition ; but this was only true in so far as it had reference to a man who was bending everything for the suc- cess of an ideal object. He was an idealist of the truest type. His entire character is expressed in the saying, " Be sure you are right, then go ahead." He was a hard and exact student of his position and responsibilities, and tried his best to fulfill them. He was not generous, as the world calls it, to the opinions of others. In per- sons occupying such positions, generosity, which in general soci- ety becomes a virtue, is nothing but a weakness. Gerlach was ex- ternally cold and autocratic, with the handsomest and cleanest-cut face I ever saw ; but behind all this coldness was a heart warm and generous, which went out to the hard-working student with almost a mother's love. He paid but little attention to the opinions of others, seldom consulted with the other professors, but, like a king among men and like a Prussian as he was, ruled the school with an iron hand so far as his powers would permit, l^aturally, men lack- ing ambition, in whom the sparks of science found no fitting mate- rial to ignite, felt ill at ease with such a man, and he felt discon- tented with them ; hence, during his whole administration of the school there was a healthy excitement kept up between these two opposing forces. But, had Gerlach lived ten years longer, there is no doubt who would have won. He died at sixty-six years of age, at Berlin, August 29, 1877, of cancer of the stomach. Gerlach died ten years too soon. At present, at the Berlin school, the practical education bears no proper relation to the scientific. The teachers are too bitterly opj)osed to one another, the one set being purely scientific, the other representing the scholastic-empiric school of which Feser speaks, which ruled absolutely until after the middle of the century. The German Government showed itself unequal to the occasion when Gerlach died. The manner of ap- pointing professors, so far as the veterinary school is concerned, is not so jus<- or good in Germany as in France. It is based too much upon literary reputation, without taking into consideration that ability to teach well, which is as necessary as extensive knowledge. Another great evil in Germany, which all countries share more or less, is fear of a young man. Other things being equal, the expe- riences of years have value, but men of genius often gain more ex- perience in a few years than the average man does in a lifetime. The moment a man ceases to be progressive he is of little use to the world. In appointing a new director at the school, there was fully as much political wire-pulling as is exercised by candidates for mayor THE VETERINARY INSTITLTIOXS OF PRUSSIA. 327 or governor in this country, and this in Germany, where Anieriean- isni is sneered at. There was tliis difference, the wire-pulling was done l>y men of unquestionable ability in some directions, but neither one of the candidates was fitted to carry on the work of progress. They were all good men, but unfortunately had too much of the old school about them to meet the demands of the time. The Govern- ment seemed to be entirely ignorant of the great failing of the school, which is the surgical clinic, and everything pertaining to it. An litter want of practical horsemanship runs through the whole thing. The treatment of internal diseases leaves nothing to be desired, but the exteraal treatment, in many cases, may be truly ex- pressed by the English word '* botch." There had never been any real practical surgery taught at the school. A great many operations are made, but seldom handsomely. The opportunity to reform all this was placed at the disposal of the German Government. But there was no one to inform it, and how should the ministers know ? The opportunity was there to reform the surgical clinic, but, what is still more to the point, the man was there also. Dr. knew that a school hospital is for the purpose of instructing students, and that the curing of patients, so long as the interests of the owner are re- spected, is a matter of secondary importance. The death-rate was perhaps a little large, but the number of recoveries in desperate cases more than counterbalanced it. Our clinical instruction was really magnificent. lie knew, better than any one at the school, its greatest failure, and studied night and day as to the best means of overcoming it. One great mistake and waste of material at the Berlin school, one which clearly demonstrates that from the begin- ning the aim of education in a given direction was never understood (it is the same at the French school), is the way in which the stu- dents practice operative surgery. // is plain hiiU'henj, not sur- gery. What sense is there in merely cutting certain nerves, opening certain cavities, ligaturing an artery or two, upon a living animal, though it be chloroformed I The students learn to cut, not to op- erate. Is cutting the whole of surgery ? In human medicine they learn to cut upon the cadaver, and it can be done equally well in veterinary medicine. But I none the less believe in taking advan- tage of our ability of practicing operative surgery upon the living animal in veterinary medicine, when chlxyroformed. But if this is limited to mere cutting, it is but butchery. To he practical, the necessary number of horses should be procured by the school, prop- erly groomed and fed ; the students to operate should be selected ; they should be privileged to select their assistants from their col- 328 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. leagues ; then they should deliver a lecture before the class as to the operation, its history, and ways of performing it, the reasons for its performance in practice, the teacher correcting or suggesting as the student proceeds. One such operation, and sometimes more, should be done daily throughout the year. The cutting exercise can be under the guidance of an anatomical assistant on the cadaver. These operations should be performed according to the strictest rules of surgery, and the different forms of treatment experimented with ; the student operating should receive the animal operated upon as a patient, and treat hira in the hospital as such ; the wounds should be bound uj), the same as in practice, and every endeavor should be made to improve the methods. All other operative surgery, either as jDracticed at Berlin or in France, is a " botch" and humbug, cruel to animals and degrading to the profession ; but the above plan is dignified with a scientific purpose ; it may serve two ends at the same time — properly exercise the student, and serve as an experi- ment by which general surgery may be benefited, and some new method find proof or contradiction. It is in unison with the true purpose of a school, the perfect union of theory and practice, which makes up the science of medicine. Were this the only error of the Government in the management of this school, it would be fortunate indeed. But, not satisfied with making an error in one direction, they must equal it in another. At the school was a young man of marked genius, of genuine scientific spirit, who was ranked as prosector in anatomy, the only trouble being that he knew too much, and was not to be brought into the scholastic-empiric leading-strings. The non-progressive tricksters, unable to control, resolved to get rid of him. As in England in- cumbrancers have often been confined in lunatic asylums, or great men banished by imbecile governments, so they sought to send him to the Russian frontier to watch the rinderpest. A man of science to act as an ordinary policeman ! was ever anything more ridiculous ? Fortunately, other powers existed. Instead of banishment to the Russian frontier, our young assistant received government aid to pur- sue the study of comparative anatomy under Gegenbauer and Wal- deyer. He was the man above all others to take Gurlt's place in vet- erinary anatomy ; ay, more ! he recognized the practical needs, and his lectures were models of scientific foundation applied to practical ends. One would think that such a man could not fail of apprecia- tion ; but such was not the case. He received a call to Dresden, and the Prussian Government, blind to its own interests, the direction of the school false to its duties to the profession, quietly let him go. TOE VETERINARY INSTITUTIONS OF PRUSSIA. 329 The Buildings. As one approaches the school from " Louisen-strasse," he is struck at once by the imposing building which marks the entrance, and serves as a residence for most of the teachers. The front wall of that part of the building, which serves as entrance to the grounds in the rear, is embellished with busts of Aristotle, Absyrtus, Ka- nuuzini, Liincisi, Lafosse, Pessiua, Bourgelat, Kersting, Cuthenius, Langermann, "NVollstein, and Abildgaard, men intimately connected with tlie birth of veterinary science. The accommodations for the residences of the teachers are liberal in the extreme, and in many respects the suites are really niagniticent. In this building are three lecture- rooms, and one for chemistry and physics, with a])propriate cabinets. The tine library, of some ten thousand volumes, espe- cially rich in valuable historical works, is situated in this building. The students are allowed to take books home and to keep them a reasonable length of time. On passing through the corridor of this building, the line grounds of the institution, with their winding walks and grand shade-trees, make a most pleasing impression upon the visitor. The anatomy building and museum is, strange to say, almost spoiled, so far as appearances are concerned, by being situated in a hollow, when sufficient commanding ground was and is to be had to show the truly fine architectural proportions of the building. It was drafted by the celebrated architect Langhans, and the main portion, which was built under his direction, is fretpiently pointed out as an example of his genius. In the basement is the dissection- room, with accommodation for two hundred students. Like many older German buildings, it is miserably ventilated, but it would be well lighted were it not for its abominable situation. The anatom- ical lecture-room, which is also used for the same purpose by the physiologist and pathologist, is without d(nibt the finest of its kind at any school. It can seat some three hundred students, the seats being arranged in an amphitheatre, the entrance being in the cen- ter ; it is lighted entirely from above. The preparations are ele- vate" 1 upon a table from the room below. The Physiological and Pathological Institutes, two fine build- ings, costing with their appointments some §00,000, are something which no other veterinary school has in the world. In the Anatomical Institute is situated also the microscopical laboratory, with microscopes for the class, and every convenience for work in this branch of stud v. 330 THE ESTABLISHMENT OF THE YETERIXAEY SCHOOLS. As we turn to go toward the horse hospital we pass that for dogs, with accommodations for about fifty, and fitted up with a small laboratory for chemical and microscopical examinations. The attendant resides in the building. The dog practice is very large at Berlin ; one good feature is, that if a dog bites any one in the city, he can report it to the police, and tlie owner tnust bring the dog here to be watched for the requisite number of days with refer- ence to rabies. Tlie horse hospital has room for about one hundred and thirty patients, many of the stalls being boxes; the stables surround a court, in which the free clinic is held. A new and handsome stable was added during Gerlach's direction. In this stable is the labora- tory for clinical examination. The stables are fine and clean, but they need the genius of an English or American head groom to make them what they really should be. The fees for patients taken into the hospital are in general fifty cents per day, which includes every expense ; operations are all performed free of charge. There is a special department for animals affected with contagious diseases, or in which the same are suspected ; another for forensic cases, for which a fee is asked in addition, as well as for the exact examination of horses. In both cases a warrant is given, and the questionable animal must remain at least three days, during which time it is tested in every possible manner. Casual examinations cost nothing, but no warrant is given. There are also special stalls for animals with cerebral troubles, so that they can not injure themselves, so far as it is possible to prevent it. There are two large halls for operations. There is also a cow-stable, holding some forty head, besides sheep, goats, swine, rabbits, etc., which are to be used for experimental purposes. The servants of the school live in build- ings on one side of the court. At one entrance of this inclosure is the pharmacy, treasury, and some teachers' and assistants' residences. The patients in the open clinic receive advice free, but pay for medicines prescribed at the regular price of the drugs, without the cost of preparation at the pharmacy. The students prepare all medicines, under the guidance of the assistant to the teacher of chemistry. The patients in the hospitals are divided equally among the senior students, each of whom directs and looks out for them as if in actual practice, being guided and questioned by the teachers. Each day the students hear a special lecture npon some selected patient, illustrating some special phase in the progress of certain diseases. From the large amount of material at command, the teacher is enabled to follow a certain course in these clinical talks. TUE VETERINARY IXSTITCTIOXS OF PRUSSIA. 33 1 Practice and lectures upon auscultation and percussion form a very strong point in the clinical instruction. There are, during the last half year of a graduating class, two chusses of students in the hos- pital, those of the lower acting as assistants to their seniors. On the graduation of the latter, the othei*s then have a full year to themselves, when the same coui"se is again pni-sued. Everything necessary to absolutely perfect instruction is present at this school, the ffuidin": owers which can give the diploma to veterinarians : The diploma for veterinarians for the German Empire can only be given by the central powers (" Centralbehorden ") of such states of the empire in which one or more veterinary schools are situated ; consequently, at the present time, by the appropriate ministers of Prussia, Bavaria, Saxony, Wtirtemberg, and Hesse. (There is no independent school in Hesse, but the university at Giessen has a vet- erinary department.) II. Regulations with reference to the qualifications of candidates : The veterinary diploma is only to be given to such candidates as have satisfactorily stood the fixed examination. The examination is divided into two inirts : 1. In the natural sciences ; and, 2. In the technical branches of study. The examination must take place at a German veterinary insti- tute. The examining body consists of the du'ectors and teachers of the THE VETERINARY INSTITUTION'S OF PRUSSIA. 335 institute, with such persons as shall be ordered to be present by the apjiropriute minister. The composition of the examining commissions in the different sections of the examination is regulated b}' the ministers. The director conducts the whole examination. The Examination in the Natural Sciences. — 1. Conditions for competing. The candidate must testify : {a.) That he has had the rcHpiisite education. He must have the proper certificate of having been prepared to enter the first class (''prima") of a gymnasium, or of a first class "real" school, in which the study of Latin has been obligatory, or of such an educa- tional institute as is recognized by the Government as of equal standing with the above. {h.) After having acquired the requisite scientific preparatory education, he must have studied for three sessions (one and a half year) at a veterinary or other high scientific school of the German Empire. The period for the examination in the natural sciences, as well as the notification of the candidate of his fitness to take part in it, is arranged by the directors of the respective schools. The notification of readiness to participate in the examinations, and the certificate of his having fulfilled the above conditions, must be handed by the candidate to the directors and indorsed by him. (The schools have especial forms for this purpose, on which each teacher testifies to the regular attendance of the students at the respective lectures and demonstrations.) The following are the branches in which the candidates are to be examined : Zootomy, inclusive of histology, physiology, botany, chemistry, physics, and zoology. The examination is oral, and public. Its aim is to ascertain if the candidate has obtained sufficient knowledge in the above sci- entific branches to warrant his proceeding with the study of the strictly professional ones. Only four candidates can be examined at one time. The examining commission consists of the director as chairman, and at least three associates. A complete account is kept of the progress of the examination by each candidate in each .section of the examination. The examination in chemistry and physics, the " tentamen physi- cnm " of the medical examination, or the })harmaceutical examina- tion, may be taken as an ecpiivalcnt to the above examination in the same branches at a veterinary school. 336 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. The results of the examination are to be indicated as follows : A judgment is to be given on the results of the examination in each of the above branches. The judgments are as follows : " Sehr gut" (excellent), "gut" (good), "geniigend" (satisfactory), "unge- niigend " (unsatisfactory), and " schlecht " (bad). The judgment in each branch is to be given by vote of the ex- amining commission. In a tie-vote, that of the director (chairman) decides. The candidate has passed his examination when he has at least received the judgment " satisfactory " in each individual branch. The conclusive judgment " excellent " can only be given when the candidate has passed in the majority of the branches as " excel- lent," and in the remainder as " good." The conclusive judgment " good " can only be given when he has passed in the greater number as " good," and in the remainder as " satisfactory." The conclusive judgment " satisfactory " can only be given when he has passed in the majority as " satisfactory," and in no branch as " unsatisfactory." The conclusive judgment " unsatisfactory " is given when the candidate has not passed in each branch with " satisfactory." If the candidate has received the judgment " unsatisfactory " in more than two branches, or as " bad " in more than one, or in one as " bad " and another as " unsatisfactory," he can only receive the conclusive judgment of " bad." Repetition of the Examination. — When the candidate has re- ceived the conclusive judgment of "unsatisfactory," he may be allowed a second examination at the expiration of three months ; it is only extended to those branches in which the candidate has re- ceived the judgment of "unsatisfactory" or "bad." When he has received the conclusive judgment of " bad," a second examination can only be permitted him at the end of one year, and is to be extended over all the above-named branches. A second I'epetition of the examination can only be allowed a candi- date with the consent of the minister. The Expense of the Examination. — For the first examination, twenty marks ($5) ; for a repetition of the same, ten marks (§2.50) more. The Technical Examination. — For admittance to this examina- tion the candidate must present his certificate of having successfully passed the examination in natural sciences ; and, secondly, he must bring a certificate of having attended lectures for seven sessions at THE VETEKINAUY INSTITUTIONS OF PRUSSIA. 337 a German vetL'riiuiry institute, or other German academy, and have heard lectures on the succeeding subject^, whicli must be testified to by tlie appropriate teachers: Zootomy and histology, inclusive of practical study in both branches; physiolttiry ; botany (anatomy and physiology of plants, classification, and ] tract ice in determina- tion of species; the Berlin school has a special professor of botany from the university) ; chemistry, inorganic and organic, with ])rac- tical exercisL's ; physics; zoology; general ])atli()lugy and therajieu- tics ; materia medica ; toxicology ; pharmacology, with practice ; pathological anatomy, with necroscopical practice and attendance at the demonstrations; special pathology and therapeutics; sur- gery and aciurgy ; theory and practice of horseshoeing ; dietetics ; breeding ; obstetrics ; exterior of domestic animals ; veterinary police ; hygiene ; forensic medicine ; history of veterinary medi- cine; clinical attendance, with practice; and visiting clinic. I^otijicatwii of the Examination. — The period for the notifica- tion, as well as for holding this examination, is tixed by the director, with the consent of the minister. The notification must be accom- panied with the proper attests from the teachers of attendance at the lectures upon the above subjects, and a short description of the principal events of the candidate's life. The director fixes the period for the examination in the different branches. Sections of the Exaynination^ and the Regulations for the same. — The examination is public, and is subdivided into the following sections: 1. In anatomy, physiology, and pathological anatomy; 2. In the medicinal clinic ; in the surgical clinic ; in operative surgery ; in phannacology (practical and theoretical) ; 3. The conclusion. The examinations in the different sections follow in immediate succession. No candidate can enter upon an examination in a section until he has passed in the previous one. In the examinations in anatomy, physiology, and pathological anatomy, the candidate has to follow the following course: 1. To demonstrate and open one of the cavities of the body in the pres- ence of the examining body ; 2. To explain an ostcological and syn- desmological preparation ; 3. To demonstrate and prepare an ana- tomical preparation ; 4. To prepare and explain histological j>repa- rations in the presence of the teacher; T). To give an oral disser- tation upon a physiological subject ; 6. To make an autopsy of a disea.'^ed animal, or one of the cavities of the same, or to demonstrate a pathological specimen, and in both cases to reduce the results to 22 338 THE ESTABLISHMENT OF THE VETERINARY SCHOOLS. writing; further, to prepare and demonstrate pathological speci- mens with the microscope. The tasks in anatomy and physiology are given to the student by lot. The commission for this examination consists of three members. In the clinical examination the candidate has — 1. To examine an animal having an internal disease, and to make the diagnosis and direct its treatment for three successive days ; 2. The same with an animal having some surgical disease. In both cases the candidate is isolated, and has to prepare a written history of his patients and their diseases, their pathology, treatment, and the probable results of the case. The oral examination takes place in each case after the written descriptions have been handed in. The candidate must prepare the medicines exhibited to the patients. The candidate has, further, to perform, demonstrate, and explain three surgical operations upon a living animal ; also, to demonstrate two fresh or dried officinal vegetable preparations, as well as to recognize two chemical-pharmaceutical preparations, give their ele- ments, formula, etc. ; also, to stand an examination in materia med- ica, toxicology, etc. The operations, as well as the above-named medicinal objects, are selected by the students by lot. The examining body in each branch consists of two members. The conclusive examination can extend over all branches of study, so far as they have not been the object of sj)ecia] examina- tions in the above sections. Only four candidates can be examined at one time, which must take place under the supervision of the director and at least three other members. Each member of the commission must occupy at least ten to fifteen minutes with each candidate. A special written report must be made with reference to the examination of each candidate in each branch, and indorsed by each member of the commission. The judgments are given in the same manner as before. The repetition must take place in the next year, and may extend itself to all branches of study. A second repetition of the examination can only take place with the consent of the minister. The written part of the examination and the written attests of the examining commission must be placed before the minister for approval. The costs of this second examina- tion are sixty marks ($15), and the repetitions fifteen marks each. TUE VETERINARY INSTITL'TIOX.S OF TRrSSIA. 339 If a cainliJate retires from the examination, a proportionate part of the fees fur the sections he has nut been examined in ^^•ill he re- turned. (The fees for the examination of the military stndents are paid by the war department.) Conclusive Judgment. — This is given after the examination in all the sections luis taken place. It is given by vote, and is influ- enced by the judgments obtained in the sectional examinations. The judgments are the same as for the sectional examinations. The chancellor of the empire is empowered to absolve a can- didate from single conditions of the examination upon reasonable grounds. The names of the graduates are published in the official organ, from which these regulations are taken. The military students arc absolved from the examination in horseshoeing, having passed it before entering the school. The course is extended over seven sessions (three years and a half), and. as the military students must first serve for six months in the military school for farriers, their course of study is in reality extended over four years. The course of study at the veterinary schools of Germany is as follows : First Session ( Winter). — Introduction to the study of veterinary medicine ; physics ; inorganic chemistry ; general zoology ; zootomy ; dissection. Second Session {Summer). — Organic chemistry ; botany ; zoology of the vertebrata ; histology and embryology ; physiology (1) ; chem- ical practice in the laboratory ; practical histology'. Third Session ( Winter). — Physiology (2) ; exterior of the domes- tic animals ; breeding ; dissection in anatomy ; lectures ; practice in the pharmacy ; repetition of lectures in chemistry and physics. Fourth Session {Summer). — General pathology and therapeutics; pharmacognosy ; pharmacology, toxicology, and practice in the art of writing and combining prescriptions; practice in pharmacy; horseshoeing. Fifth Session ( Winter). — Special pathological anatomy ; special pathology and therapeutics ; s]X.*cial surgery ; operative surger}', with practice; clinic fur large animals ; clinic fur small animals. Sijcth Session (Summer). — Dietetics ; obstetrics ; animal pests, veterinary ]iolice ; microscopical practice in pathological anatomy ; clinics ; visiting clinic. Seventh Session ( Winter). — Forensic medicine ; history of vet- 340 PRTJSSIAX REGULATIONS FOR COXTAGIOUS DISEASES. erinary medicine ; clinics ; visiting clinic ; practice in writing legal papers with reference to veterinary police and forensic medicine ; repetitions in anatomy and physiology. There is room left for an eighth session in the schedule, which it is to be hoped will be soon added to the curriculum. THE PRUSSIAN LAWS AND REGULATIONS FOR THE SUPPRESSION OF CONTAGIOUS ANIMAL DISEASES. The first attempt at the organization of a veterinary police, and drafting regulations for the suppression of contagious animal dis- eases in Prussia, dates back to 1803. It has been the object of constant improvement, and it seems that a translation of the prin- cipal parts of these laws can not be without value to the people of this country. "We have nothing in a condensed form to which our legislators can refer when drafting regulations for the su2?j)re8sion and prevention of contagious animal diseases ; and as these questions are sooner or later to take no insignificant part in national legisla- tion, their appearance here is justified. The supreme supervision of the veterinary institutions of Prussia rests with the Minister of Agriculture, who is assisted by a resident director, and a board of assistants, composed of lawyers and eminent agriculturists. In addition to this there is a veterinary council, the duty of which is to give the decisive opinion with reference to all technical points in relation to veterinary questions. The active members are selected from the teachers at the veterinary school and the department veterinarian of Berlin, with Professor Yirchow and other eminent medical counsel. In Prussia there were (1879) 36 department veterinarians, 12 so- called veterinaiy assessors, who rank higher than the above, 16 fron- tier veterinarians, and 407 district veterinarians. These ofiicers have fixed remuneration for their official work, and their traveling ex- penses ; with the exception of the frontier veterinarians, they are almost all permitted to practice ; the latter receive about $800 per year, and enjoy no very enviable positions, from the difficulties and exposures, as well as the comparative isolation of their positions. Each district is further supervised by an " imperial president." The department veterinarians are named by the minister, with the advice of the council, from among those district veterinarians who have RINDERPEST. 341 especially distiiiguislied themselves in the execution of their duties ; the latter have to pass special and severe examinations, both oral and written, with reference to the duties required of them at the veterinary school : those olice for that purpose. ''If the existence of the disease is proven, or if strong suspi- cions of the same exist, it is the duty of the veterinarian to as- certain how long the suspicious phenomena have been noticed, if the diseased or suspected animal has been in relation with other cattle, if animals have been recently slaughtered from the same sta- l>le or farm, or removed, when and where the suspected animal was bought, and who the former owner was. The results of this ex- amination are to be at once communicated to the police and the local officers, in order that they may put the necessary laws in execution. If the corresponding police regulations have not been ordered, and the police representative was not present at the examination, it is the duty of the official veterinarian to at once order a preliminary separation and isolation of the diseased and suspected animals. It is also the duty of the veterinarian to notify the owner or his represent- ative in writing of these regulations. In necessary cases the official veterinarian can require the presence of the head man of the town." The Regulations in Case of Suspicion. — "The cattle of a farm (or locality) which has been heretofore free from the disease are sub- ject to the police observation when it has been confirmed ; that, among the cattle, individuals are found which have been in re- lations with animals having this disease within the last eight weeks ; when the cattle in which the disease was suspected, before the official examination, have been slaughtered, removed, or otlierwise done away with. The police have to make a memorandum of the number and characteristics (marks) of the animals in the sus- pected locality, and to make such regulations that the owner or his representative can not remove any cattle without the permission of the police. It is the duty of the police to see that these regu- lations are executed. " After the lapse of four weeks, the police must order the otli- cial veterinarian to make a second supervision of the cattle in the suspected locality. " If the official veterinarian can not at the time positively assert that the disease exists among the animals, but if the examination 356 PRUSSIAN REGULATIONS FOR CONTAGIOUS DISEASES. has confirmed the existence of suspicions phenomena which jnstify the fear that an outbreak of the disease may take place, it is the duty of the police to subject the stable to quarantine. The other cattle of the place must be confined to the limits of the owner's property. No cattle can be removed from the place, nor can food materials be removed which may endanger the extension of the dis- ease. The police may allow those animals which have not been quarantined in the stable to be used for work in the fields of the owner, or to graze when the fields or the ways to them are so situ- ated that the cattle of other owners can not possibly be exposed to in- fection. These regulations come to an end when the official veteri- narian declares that suspicious phenomena no longer exist," In case the disease comes to an outbreak : " When the disease has been confirmed, it is the duty of the police to give public no- tice of the same in an appropriate manner. The infected locali- ties are to be made known by inscriptions, ' Pleuro-pneumonia,' being placed at prominent places. " All the diseased or suspected animals must be discovered as soon as possible. All cattle in the infected locality (farm or stable) are to be looked upon as suspicious, inclusive of those which are found in isolated stables. It is the duty of the police to kill at once all animals which the official veterinarian shall pronounce diseased. If a perfectly secure isolation is possible, the police may restrain the above proceedings for a period of fourteen days, if the owner urgently requests it. The suspected animals at the infected farms must be subjected to quarantine. The removal of cattle or food from such farms must be forbidden so far as there is danger of the extension of the disease, though they may be used for work if such can be done under proper restrictions. If the disease acquires a considerable extension in a district, no cattle are to be allowed to be driven from it, or introduced into it. In such case the holding of cattle-markets must be forbidden, and, in necessary cases, in neigh- boring places also. " If the disease breaks out among cattle which are constantly kept upon pastures, it is the duty of the police to order the diseased animals killed ; such places must be so guarded that no cattle can be driven on or from them. Such pastures must be indicated by appropriate signs. If it is impossible to isolate such pastures, then the remaining cattle must be removed to more suitable quarters. If the disease is found among droves, or in cattle on the cars or in canal-boats or other means of transport, then the police have to order the diseased ones killed, and the remainder isolated. AX Til RAX, ETC. 357 " In onler that the slaughtering of suspected or quarantined cattle may immediately take place, the police are permitted to allow their removal by rail or other closed conveyance, to such slaughter- ing-places as are under the control of the state. This can only take place where no possibility exists of their coming in contact with other cattle. In such cases the police must give timely notice of the arrival of the suspected cattle. The cattle must be slaughtered subject to the supervision of an official veterinarian. This liberty is not extended to already diseased animals. " If suspected animals are removed in opposition to the above regulations, or found in places where they have been forbidden, it is the duty of the police to kill them at once. Animals which are condenmed to be killed by the authorities must be slaughtered under their inspection within the limits of the place (farm, etc.) where they are found. The lungs of the slaughtered, and bodies of those animals which have died, must be destroyed. They may be skinned upon the named grounds. The flesh of the slaughtered cattle can be removed after it has been cooled oflf. The hides can only be removed from such places after they have become com- pletely dried, unless they are directly delivered at a tannery. " The cleansing and disinfection of the infected stables must be controlled by the police, and must take place before the restrictive regulations are relaxed. The police and veterinary official must re- turn reports with reference to the execution of the laws. '" The disease is to be declared at an end when all the cattle have died or been condemned to slaughter ; when all the sick cattle have been removed, and no new case has occurred within four months from the last case of disease ; when no case of disease has sliown itself among the cattle of the infected locality for a period of three months after the last possible infection could have taken place. No cattle can be removed from such places, save for the purpose of im- mediate slaughter, until after the lapse of six months. "• The police are to notify the public that the invasion is ended, after the disinfection has been properly effected.'' Glanders. " The examination of animals (liorse, mule, ass) by the official veterinarian must take place, as a rule, in the presence of the head man of the place, or a special representative of the police. If the presence of the disease is confinned, or if there is a strong sus- picion of the same, it is the duty of the veterinarian to ascertain how long the suspicious phenomena have been noticed, if horses have 358 PRUSSIAN REGULATIOXS FOR CONTAGIOUS DISEASES. been lately sold from tlie place, or removed ; if tlie diseased or sus- pected animals have been in relation with other horses ; if so, where the same were bought, and from whom. The results of this exami- nation are to be at once communicated in writing to the local police and the head man of the place, in order that the requisite regulations maj be placed in operation. "If the regulations are not yet in active operation, and the rep- resentative of the police was not present at the examination, it is the peremptory duty of the official veterinarian to at once separate and isolate the diseased or suspected horse. The veterinarian must also at once notify the owner, or his representative, of these restric- tions. A memorandum must at once be taken of the character- istics and appearance of the diseased and susj)ected animals, and of those horses which, although not yet diseased, have been in rela- tion with them and others exposed to infection. The papers are to be at once sent to the police, so that the regulations may be ]3ut in force." Protective Begulations. — " The public are to be notified by the police in the usual manner. This notice may be dispensed with in places of over 50,000 inhabitants with the consent of the Minister of Agriculture." When Glanders is proven. — " If the presence of the disease is confirmed in a horse, it is to be at once killed. It must be done in some isolated place. In the transport to such a locality care must be taken that the diseased animal does not come in contact with others of the same species." Wheyi the Suspicion of Glanders exists. — " In the following cases the suspected animals may be killed : " {a.) When it can be proved that the suspected animals have been in relation with diseased ones. " (b) "When a suspicious nasal outflow, hard and swollen glands, especially the intermaxillary space, suspicious nodules in the skin, suspicious tumefaction of one or more limbs exists ; especially when one or more of these phenomena are present at the same time ; or when, at the same time, difficulty of respiration or staring hair is present with some of these phenomena. " ( ; besides, it would be necessary for the first few years to treat the offspring of that immense number of stock, entailing an increased expense. Other Diseases. — Many reported cases, in young stock, upon in- vestigation, prove to be the result of the presence in the bronchial tubes of the parasite Stron/julus filai'lce^ species Micruris. In some localities it exists to an alarming extent, causing a severe mor- tality. Its symptoms being similar to pleuro-pneumonia, it is usually mistaken by the farmers for that disease. It readily yields to scien- tific treatment; but, owing to the immense loss it entails, should receive legislative consideration. Ilog-cholera, likewise, exists in the southern part of the State, and is creating a good deal of alarm, but, not coming within the provisions of the act under which we are working, has received but little attention. It is a subject that also calls for legislative action. Nt'W FacU. — That we meet forms of pleuro-pneumonia varying in degrees of vinilence is beyond question, and to that fact may be attributed the difference of opinion in regard to the efficacy of in- oculation. "When, as frequently found, the malady will run through 374 THE MEANS OF PREVENTION. a herd, causing perhaps the loss of but one or two out of a large number of animals, and affecting the remainder to so slight a degree that the layman can scarcely appreciate it, we must admit it differs widely from that form which (under similar circumstances) causes a mortality of fifty and sometimes sixty per cent. To the former type may be traced the cause for the disputed question. Does an animal once affected ever recover ? We are inclined to the negative side of the question : after having destroyed a number of cases that have passed through a mild attack of the malady, we have found upon examination lung lesions generally in an encapsulated form. These cases we are willing to admit are perfectly safe to mingle in a herd, so long as the capsule walling up the disease-germs re- mains intact, but if it should break down, a condition we may very reasonably look for, and those germs be allowed to escape, shall we not have another outbreak ? If it is true, as claimed, that the dis- ease-germs are imprisoned and lie dormant in the lung for months, even years, the question very naturally presents itself, Do they in the mean time lose their infecting principle? Until this vexed question is settled beyond doubt, we advise as a means of preven- tion the destruction of all such cases. Very respectfully, your obedient servant, Ja3ies C. Coelies, D. Y. S. To General W. H. Sterling, 249 Washington Street, Jersey City, N. J. The following is a summary of the work accomplished : I^umber of cattle inspected, 40,309 ; diseased, 572, of which 315 were de- stroyed. It will be seen from this report that " dealers " in cattle are a source of great trouble to those intrusted with the execution of laws against contagious animal diseases. I wish also to express my earnest opposition to inoculation, so far as it may be advocated as a preventive means for this country. Were it absolutely necessary that every head of cattle in this coun- try should have the disease, either in a natural or artificial form, in order to put a stop to its ravages, then this procedure would be jus- tifiable. At present it is not. The disease has not as yet acquired any very devastating extension, although, from the want of really competent veterinarians, it is doubtful if we know exactly to what degree it has extended in all the States where it is now domesticated. We shall know in time to our cost. Were our people so educated that they could really appreciate the truly devastating character of this animal pest ; were our legislators at all adequate to the demands A NATIONAL VETERINARY POLICE SYSTEM. 876 we Lave a right to make upon thom, there would not be an isolated case of lung-plague in this country in six months from this time. Alas I unity of action is the last thing to bo expected of an Ameri- can Congress. While political pettifoggers are squabbling over party- bones, the people are being daily robbed of millions of dollars by the ravages of different animal pests, and that other pest, equally dangerous, quacks. If all the cattle having this disease could be at once killed and paid for by the Government ; if all suspected animals, which in- cludes all which have been in contact with them, could be isolated and quarantined, or else at once killed, and sold for flesh ; if it were possible to subject all cattle entering our territory from Canada or from across the Atlantic to an appropriate quarantine — then we might soon be rid of this destroyer, and keep it foreign to our shores. This is impossible at present. "We have not the necessary laws, and it is still more doubtful if we have at our command the necessary number of qualified veterinarians. I wish to say a word about cattle-inspection at points of delivery. In one sense of the word it is useless. Unless an inspector knows that a given lot of cattle have come from a suspected locality, he has no more right to condemn them for pleuro-pncumonia contagiosa than for an ordinary pneumonia before an autopsy has been made. Many people seem to think that it is easy to recognize this disease in the living animal, whether one knows the history of the case or not. In truth, no two animal diseases present so many difficulties in the way of recognition of their true character as this disease and pulmonary glanders. The differential diagnosis between a de- veloped case of lung-plague in cattle and tuberculosis is by no means difficult, although many would have it that it is so. All cat- tle, or other animals destined for transport, should have a "clean bill of health" signed bj' a State veterinarian at the place of pur- chase, and attested to by the proper legal official. This should be an invariable nde of animal transport. With this precaution, and careful regulation of the cattle during transport, there is but little danger of the spread of such diseases from one point to another. It is evident that, if the laws in the respective States were different in this regard, all action would be made null and void. All pneu- monias are not pleuro-pneumonia ; yet, how is the inspector at the place of destination or final shipment to distinguish one from the other, unless he knows the history, or has condemned one to necro- scopical examination ? The truth is, but few veterinarians in this country really know the pathological character of an ordinary bovine 376 THE MEANS OF PREVENTION. pneumonia. Cattle are so phlegmatic, they can endure so much, that but very few of them die from this disease ; yet it is a fact of pathological interest, at least, that the fully developed simple pneu- monia of cattle is the only form among our domestic animals which bears a strong resemblance to the cheesy pneumonia of man. Mr. John Gamgee says that "England loses two million pounds sterling annually from this disease." * Fleming says : " The losses from only two exotic bovine mala- dies (contagious pleuro-pneumonia, and the so-called 'foot-and- mouth disease ') have been estimated to amount, during the thirty years that have elapsed since our ports were thrown open to foreign cattle, to 5,549,780 head, roughly estimated at £83,616,854. The late invasion of ' cattle-plague,' which was suppressed within two years of its introduction, has been calculated to have caused a money loss of from five to eight millions of pounds. But these examples and estimates, after all, give but a slender idea of the devastation, misery, embarrassment, and loss that have been due to ignorance, apathy, and neglect of the teachings of veterinary science, which must, nevertheless, claim the merit of having conclusively demon- strated that the most formidable diseases can be readily repressed, or altogether abolished, though not by attempting to cure them, and, having done this, nothing more remains than to indicate the steps necessary to make the legislation of a wise government effective in its dealings with animal plagues in general." f It is scarcely possible for us to comprehend the monetary loss this disease has caused since its history began, not to speak of the misery it has brought upon many poor people. There is at present but one rule for its treatment : No temporiz- ing. Immediate slaughter, and redemption by the Government. We have, fortunately, not yet been visited by the rinderpest. Should that day ever come, there will be mourning in the land — Columbia weeping for her property, and little comfort will she get from church or State, unless we mend our ways and act more intelli- gently. The people of this country have no idea as to the real nature of a contagious animal disease. To this end it may be possible that they need the presence of this destroyer. The horse epizootic of 1871 and 1872 was certainly infectious enough, but this disease is equally infectious, and so much more devastating that it is impossible for words to fitly express it. It is not slow and sneaking in its prog- * " Report on the Cattle Diseases in the United States," Washington, 1871. I " Animal Plagues," introduction, p. xxxiv. A NATIONAL VETERINAKY POLICE SYSTEM. 377 ress. It breaks loose in a ni^lit ; ay, in an hour; and, like a (lemon incarnate, it frequently sweeps the bovine family before it. Russia loses millions every year from it. Germany scarcely passes free from its ravages for any single year, though they are at present very quickly stamped out. In 1878 she lost 2,500 cattle, having a value of about half a million dollars. England lost some twenty-tive million dollars' worth of cattle in the last great invasion which she suffered in 1805, 1800, and 1807. AVe have in this country the " Texas disease " of cattle, the real nature or causes of which we at present know very little about. It produces no inconsiderable loss each year, however, and the States, the frontiers of which border on lands where this disease seems to be domesticated, have been obliged to make laws regulating the traflfic in cattle. The Agricultural Connnissioner pretends to give some statistics with reference to the losses the people suffer from swine- plague. In 1870 it was reported that the loss from this disease alone amounted to some 820,000,000. The report for 1878 gives $30,000,000 as the amount of loss to the country from all conta- gious animal diseases. These are estimates — nothing more. It is absolutely impossible to gain any reliable statistics in a country where there is no system of veterinary laws or an efficient veteri- nary police. The value of reliable statistics, with reference to the extension of contagious disease among our animals, can not be over- estimated. Until we have them, it will be useless to hope for much conformable legislation. Every observing citizen must at once per- ceive the immense tax which these diseases impose upon the nation. It is highly probable that, were the real facts known, their rav- ages have cost the people more in the last hundred years of our ex- istence than our national debt amounts to. Every one should know that, if not absolutely preventable, yet it is possible for a competent veterinary police to reduce these losses to a very low minimum. Cxermany, with its efficient code of laws and veterinary police, is continually proving this ; while Britain and ourselves as frequently give proof of the incapacity of our respective Governments in this regard. Xo preventioii can be hopei'otection. This is the sole and only prin- ciple which should guide legislators in drafting laws. Especially is A NATIONAL VETERINARY POLICE SYSTEM, 379 this true with reference to those we are now considering. This prin- ciple is ecpiuUy applicable to our respective States. Without such centralization — i. e., without sotne one controlling, inciting, directing ])ower — nothing was ever yet acconij)lished. The question of regu- hition is to tind the proper relation of such a power to the other ele- ments or powers by which it is surrounded, that the greatest good for all concerned may result from their united action. This prin- ciple is one of true politics. "Whether it be true repul)licanisin or democracy I do not know, and care even less. Tiie family can not well exist without its head. The ship can not pursue her coui-se over the sea without her responsible captain. No business has ever succeeded without its competent and accountable head. " Too many cooks spoil the broth " is a homely but true saying. As a nation, we stand at present impotent before the ravages of the infectio- contagious animal diseases. AVe shall never get much beyond this impotent stage if we adhere to the State-rights doctrine with refer- ence to the suppression and prevention of these diseases. This doc- trine requires special notice at the present moment. "We are ap- proaching a period in our history when the different State Legisla- tures will be called upon to make some kind of laws and regulations with reference to this question. Reflecting men, those best compe- tent to judge, are also endeavoring to urge the General Government to do likewise. The real question, which must be discussed with cool and unprejudiced brains, is, Which step is the more likely to be of most lasting benefit to the people of the whole country, as well as those of sinjrle sections I Dr. Bowditch, in his valuable essav, " Pub- lie Hygiene in America," tells us that we have at i)resent (1876) twenty-one States without either law or regulation looking to the suppression or prevention of these diseases. In ten States there were some, and sixteen were reported as indefinite, while from one State it was impossible to gain any information. Our markets are all without the supervision of competent inspectoiv, notwithstanding the great danger to the poorer classes, more so than the rich, of dis- ease of a disturbing if not fatal chamcter, from the consum]>tion of diseased meat. No State in this Union, so far as I know, has a State veterinarian in the true sense. In some there is a veterinarian attached to some agricultural society ; in others, to a cattle com- mission. The few regulations which exist in some States are totally inadequate to the purpose. They almost entirely fail in properly defining the duties of the public. Quacks are in no way made re- sponsible for the proper notification to the authoritii-s of the pres- ence of a suspected contagious disease in a given animal. In fact, 380 THE MEANS OF PREVEXTION. our laws are of such a nature that, while in some cases, as in pleuro- pneumonia, they allow of quite satisfactory action, because of the very limited extension of the disease, in others, as glanders, they are next to useless, because of the great extension which the disease has already acquired among our horses. One of our greatest errors is, that we have made no use of the few competent veterinary practi- tioners in the country. Our laws serve only to make one man very prominent without being of the service to the State that they should be. It is in the interests of the peoj)le that the veterinary profession be made of use, and not that a single veterinary com- missioner, in unison with several citizen members, have the en- tire work to do. It can not be done, as is sufficiently proven in Massachusetts, where we have an old and well-tried veterinarian on the cattle commission. While they did kill out plem'o-pneu- mouia, it has been sufficiently demonstrated that they are next to powerless in fighting glanders single-handed. We seem to think that, having organized a " cattle commission," our work is done ; as if there were no other animal diseases worthy of consideration ! Finally, in some States they attached a section with reference to glanders, and with that we have thus far rested content. Such a system is next to useless. It can never lead to any reliable statis- tics. These laws or regulations in the different States have very little in common. In many States they are simply dead letters, there being no competent authority to see them properly exe- cuted. " What is everybody's business is nobody's." In no one sense is the saying, " In union there is strength," more strictly true than in combating contagious animal diseases. It may be positively asserted that, if we adhere strictly to the principle of State-rights in this regard, all our endeavors to prevent and suppress these dis- eases will be weak and of but httle avail. All must admit that the manner of viewing any given subject is not the same even among a few individuals. How much less likely is this to be the case among large bodies jealous of each other ! These great differences of opinion are largely dependent upon a difference in information and education by the individual members ; and, secondly, upon a varying degree of appreciation of the nature of a threatened danger. A large amount of reading and reflection is necessary before men are competent to logically legis- late on any given subject, and on none more so than that we are at present considering. Hence it is that in some States we should have more or less suitable laws with a corresponding execution of the same, while in A NATIONAL VETERINARY POLICE SYSTEM. 3S1 others quite tlie contrarv would be the case. Only M'hen a coin- inon chm«;er exists, or when there is some ccntriil and controlling power to spur men on to their duty, and warn them of their dan- ger, do we have energetic and uniform action. The results of this condition of things may be made more a])i)arent by supposing that pleuro-pneumonia is present in two or more adjoining States. The authorities of one of these States, thoroughly aware of the dangers to which her bovine population is exposed, and not regardless, we may hope, of their duty to sister States, have made ample provision of money, and drafted a]ipropriate regulations for " stamping out " the disease. The}' have selected special persons to execute the same. On tlie other hand, the authorities of an adjoining State have de- cided to follow the temporizing policy. They seem to fear a primary outlay, not appreciating that a small outlay, well expended, at tirst, may save an immense expense in the future. The regulations of this State, and the manner in which they are executed, are of that form which serve to express a fear of the ill-will of the people. Her legislators seem to have their attention more earnestly fixed upon influences likely to interfere with the next elections, rather than on their duties to the people. They appear to utterly ignore any responsibility with reference to their duties toward adjoining States. They make of their State a hot-house from which pesti- lential germs may be disseminated, not only to adjoining States, but even to those more distantly situated. Of what use, then, is all the outlay of time, money, and labor by the authorities of the first- named State i To prevent the disease extending over her borders, she must treat her sister State as an enemy. She must place an em- bargo, not only on all cattle from that State, but upon all passing throriffh that State. She can allow no cattle to cross her frontiers from a State where the laws are less stringent, or poorly executed, without first subjecting them to inspection, and frcijucntly to quar- antine. Were this regulation carried out along a long line of traffic through different States, it requires no stress of the imagination to perceive the great disturbances which our trade in domestic animals would suffer. In the case of glanders it will be absolutely impos- sible to keep it properly confined within narrow limits, unless we have the same laws and regulations for every State in the T'nion, and equally stringent execution of the same. Otherwise, such horses can be nm backward and forward across State boundaries, or the result will be that the disease will acquire an undcsiral)le exten- sion in those States where the laws are lax, or where they are but dead letters for the want of proper execution. The people of such 382 THE MEANS OF PREVENTION. a State will then suffer losses which thej richly deserve. We find it necessary to have national laws to prevent the introduction of con- tagious human diseases from foreign countries. Is it not equally necessary that we have such a code of laws as will best protect the animal property of all the people in this country to the same degree, and not (as will be the invariable result, if we leave the States to make their own laws) have such codes, as to offer but incom- plete protection to the people of any State ? The universal testi- mony of all men who have busied themselves with the suppression of contagious animal diseases is, that it is rendered doubly difficult because of the ease with which owners can get rid of diseased or suspected animals. Dealers are, in general, only too willing to take advantage of such opportunities to get cheap bargains, and they are equally regardless of the interests of the community in transporting them. A man sick with a contagious disease gladly stays at home. But if a person practicing as a veterinarian informs most owners of the presence or the suspicion of a contagious disease among their ani- mals, the owner's first endeavor is to get them off ; and experience has proved that many of them care very little about the danger of infection to which they subject the property of other men. This is absolute testimony to the necessity of regulating the duties of em- pirics and quacks in the practice of veterinary medicine, as well as owners. The duties of graduates must naturally also be regulated by law. With reference to the trustworthiness and public spirit of owners, a most interesting example occurred in connection with trichinosis in swine within a few weeks. A gentleman came to me one afternoon, and in a very bombas- tic manner requested me to examine two pieces of pork. These hogs had been fattened by himself, and, as he expressed it, were " blooded Berkshires." It was, or is, his custom to fatten two each year, and present pieces of " home-fed pork " to his friends at Christ- mas. One piece was free, but the other was very badly trichinous. On showing them to the gentleman upon a hot table attached to the microscope, so that he could see the worms squinn about, he called me a " swindler," and intimated that I had introduced them surrep- titiously into the specimen. Convincing him of his error, however, he somewhat recovered his temper, and remarked that he certainly could not think of presenting such pork to his friends, and that some would have to go without their present this year. " But there is no law against my sending it to market, is there ? " To which I am sorry I had to answer that there was not, nor could I prevent it ; but that I thought the rendering establishment the best place for it. A NATIONAL VETEUIXARY TOLICE SYSTEM. 383 The answer, and tlie manner in which it was given, were sonietliing really worth recording. " Thank God, there's some freedom left in Massachusetts ! " said this pattern of Boston aristocracy ; for the gen- tleman is one frequently })ointed out as an example of honesty and Christian virtues. '* Thank God, there's some freedom left in Mas- sachusetts'' for a -wealthy man to sell pork which, if a little under- done, can cause the serious illness of persons consuming it, or even death ! Is there not need for laws to prevent the sale of improper food by technical examination? If a person of this man's worldly standing has no moral responsibility, what have -we to expect from the ordinary owner of hoi'ses, cattle, etc. ? Every one at all ac- quainted with the internal arrangements of the German Empire must know that there is far more jealousy betw'een the different kingdoms of which it is composed than there is between the differ- ent States composing our Union. Notwithstanding this, these gov- ernments have seen the absolute necessity of an imperial code of laws for the suppression of the contagious animal diseases, experi- ence having proved the state laws hitherto in existence insufficient for the purpose, there being here and there a dissimilarity which re- sulted in evil consequence to the people of one state or another. "We need not copy literally the German laws, but we can study them and adapt them to our uses. It is high time that active steps were taken, in this country, in this direction. To this end our national Congress should either select a commis- sion of honest men, or authorize the President to select such from among the leading stock-raisers of the country, one from each of our great geographical sections. This commission should select three of the ablest approved veterinarians in the country, and two able and non-partisan lawyers. These five men should be paid to make a study of the veterinary police laws and institutions of such countries as are worthy of consideration, and should then draft a national code of laws and regulations in strict accord with the re- suits of tlie best scientific research, and with exact regard to logic and cxplicitness in language. These laws should be accepted by Congress and by the respective State Legislatures. Such a plan in no way interferes with the right of States to make such special laws and regulations, in addition to tlicm, as their local needs, posi- tions, or other requirements may demand ; and furthermore, as will presently be seen, our plan will provide each State with a competent and trustworthy body of men to execute the laws. From these three, and others, if they desire, should be selected a person to be known as Yeterinarj' Inspector-General of the United States. This 384: THE MEANS OF PREVENTION. position should never be disgraced by being filled by political favor- ites of congressmen, secretaries, or commissioners. The present Commissioner of Agriculture would gladly have the appointment given over to his dispensation. Fortunately, Congress has not yet seen fit to give him such a liberty. A man must, at least, know something of the duties of the office to be filled, if he is to appoint an incumbent. This position must be filled on its merits, and by public competition before the members of the National Board of Health in the first place ; but when the time comes, the incumbent should be elected by vote of the trustees and teachers of the national school, from among the State veterinary inspector-generals of the country. No teacher or professor of the school should ever be eligible to the office so long as they were connected with that insti- tution. In no other way should it be possible for any man to gain the position. Science is the search after truth. A scientist who uses the ways of politicians to gain a position does not deserve the name. Science is open as the day. Politics is as dark and intricate as the passages of a coal-mine, and about as dirty. Science is not politics, as we see it displayed in America. There is such a thing as political science, but it has not yet been introduced into our legis- lative halls. The great men of science have been the truest servants of mankind. Scientists are patriots, not demagogues or political hucksters, ready to sell their birthright for a mess of pottage. The "Veterinary Inspector-General of the United States should be attached to the National Board of Health, as should all State inspector-generals to State boards. The whole system of veterinary sanitary police should be part and parcel of one grand national sani- tary system, working in the interests of true preventive medicine. These officers should hold their positions until sixty years old, unless incapacitated for work by sickness. They should be liberally paid ; and, in case of retirement, their pay should be continued to them during life. The nation and the States need all their energies and time. On his death, if leaving a widow or minor children, the former should have at least two thirds of the husband's pension during life, and the children a proportionate share until sixteen years of age. The State inspector-generals should be selected by public compe- tition of approved veterinarians before the members of the State Board of Health. In each State there must be county, district, mar- ket, and other local veterinary officials. These men must first have passed a special examination, instituted for the purpose, with refer- ence to sanitary police duties, at the National Veterinary Institute. A NATIOXAL VETERINARY POLICE SYSTEM. 385 Until such an institution is organized, the competitions should take place before the members of the State Board of Health of each State. They should receive a certain amount of pay per year for othcial work, and in no case should they hold office after becoming sixty years old. They should not be subject to pensions, as their official ]iositions should assist them in practice by guaranteeing to the people their superior education. Local insjiectors, while belong- ing to the force, such as market and milk inspectors, should be paid by the respective local authorities. State inspectors, ordered to at- tend horse or cattle fairs or markets, should be paid for the time of service by the respective associations. The State should fix the price, -which should be liberal, and allow for all traveling and inci- dental expenses. We can not expect any intelligent appreciation, on the part of the public, of the value of such a sanitary system, unless we can present them with reliable statistical information on the subject. Without statistics we can not tell to what degree such diseases are domesticated in a given State, nor can we judge of our success in combating them from year to year. To this end, returns should be made quarterly by the district and local veterinary officials to those of the county, and semi-annually by the latter to the State Inspector- General, who should make an annual report to the inspector-general at Washington, who in his turn should prepare a condensed annual report of the condition and work done in the whole country — the same to be a part of the report of the National Board of Health. It must not be forgotten that this work of inspection is never to be limited to contagious diseases of animals alone, but that most espe- cial attention must be given to the study and observation of those diseases and conditions which are either known, or are supposed, to exert harmful or dangerous influences upon the health of mankind. The true veterinarian is fully a.s much a guardian of the public health as the medical hygienist. The curing of sick animals is by far the most insignificant part of his work. Prevention is the true strength of veterinary science. In this regard the veterinarian is of far more importance to humanity than the medical practitioner. The tables are exactly turned about in the two branches of medi- cal science. The doctor is strongest in practice, the veterinarian in the prevention of diseases. By the plan which we have proposed for a national veterinary police code and organization, it is self-evident that the extension of any disease over the country, or from one State to another, can be very strongly combated. In case a contagious animal disease — we 25 386 THE MEANS OF PREVENTION. will assume the rinderpest — breaks out at any place, say Columbus, Ohio, the law requires the owner, attendant quack, empiric, or regular practitioner, to at once notify the next veterinary official of the State of the suspicion or actual appearance of the disease. If the former is very strong, or becomes at once confirmed, he at once no- tifies the inspector-general of his State, who at once notifies every official veterinarian in the State, and the inspector-general at Wash- ington. The latter notifies each State general inspector, who in his turn notifies the State veterinary officials. What is the result ? An absolute quarantine of every head of cattle in this whole country. Not a single one can be moved without the permit of an official veterinarian. All transported cattle are watched from place of ship- ment to destination. Extension, under such circumstances, is re- duced to the lowest possible limit. The same is true of every other contagious animal disease. Smuggling or remov^al across State boundaries of suspected or diseased animals becomes useless, for notification is at once transmitted from the one State to the other. There is no opposition between the authorities of different States. The laws are the same. The officials belong to one organization. They are appointed for a term of years. Truly, every one must see that in this case we have unity in purpose and strength to execute the laws. State rights are respected, individual rights honored, yet both State and individual receive the fullest amount of protection for their animal property which it is in the power of science to bestow. I have said that the national veterinary inspector should be attached to the N^ational Board of Health, and that the whole ' veterinary sanitary organization should be a part of a grand national system of preventive medicine. We have a National Board of Health. Oth- ers have expressed their ideas of its work, therefore it may be allowed me to close this section of my book with some of my own, crude as they may appear. The National Board of Health was called into being simply on account of the yellow fever. Its work, uj) to the present time, has been chiefly limited to the study of that disease, and in seeking for means looking toward its prevention. This much-needed work should be amply supported, and obstinately persevered in, but we may be sure that many years will elapse before any marked success will crown our efforts. Success will come, however, if the Ameri- can people can keep their balance long enough not to cry out for a false economy, which is the last cry one should hear in this impor- tant branch of our Government. The work of a National Board of Health has, however, scarcely begun when it is limited to yellow A NATIONAL VETERINARY POLICE SYSTEM. 387 fever. Such an iiistitutiou must be the focal stimulus wliicli shall gradually cause the organization of one grand national system of preventive medicine. It nnist seek to incite reforms where they are needed, and among these none is more important than one stand- ard medical examination for the country, and one similar course of study at every medical school in the land. Xo good work can ever be done except as the result of organized effort. Centralized, that is, cohcentrated effort, is always rewarded by better results than isolated, s|X)nidic endeavor. Many of our States are still without effective boards of health, as is also the case in many large cities or towns. In only one State, Massachusetts, have we anything like State medical officers. In this State we have the " medical examin- ers " taking the place of that useless inheritance from England, the " coroner." In effective work it is absolutely necessary that the whole country become subjected to one code of sanitary laws, suitable to the general needs, while in every State, county, city, or town, such special laws must be made, and are in general, as the local needs demand. These special laws and regulations should always bear a proper relation to the general. It is the drafting of the latter which will devolve upon the national board. Once hav- ing such laws and regulations, the next thing is their execution. To this end competent sanitary officials are necessary. These ap- pointments should never be made until candidates have pa.ssed a special examination, to be fixed for the purpose by the National Board of Health for the whole country — the examination to consist in (piestionings upon the pathology, etiology, etc., of the diseases included among those generally spoken of under the headings of preventive medicine. The examinations should be made by the members of the respective State boards of health. The organization of the sanitary system in eacli State should be similar to that wliich I have [)ortrayed with regard to a veterinary organization. These positions should be points of ambition for our best young men. They should receive pay for official work. In cases where the ne- cessities of the public demanded their whole time they should Ixj liberally paid, and open to a pension in the same manner as above considered. We should therefore have a National Board of Health in connection with State boards, which sliould be in connection with local boards and health officers. These officials must be thoroughly educated in the principles and practice of modern research, and in patliological anatomy and necroscopy. The professional members of the State boards of health should be appointed by the Governor from among the most competent of the sanitary officers. They should 388 THE MEANS OF PREVEXTIOX. all be paid, and hold office until sixtj years of age, or during activity. Those members who are required to devote their whole time to the service of the State should be pensioned on retirement. The State can never afford to be a " bummer." Men who can afford to work for honor alone are seldom fitted to serve the State well. This principle of working for the State for honor alone, so common in certain positions in this country, can not be too strongly condemned. It is death to young men, and equally detrimental to the public good. A State which is too poor to pay competent men for the work it requires of them is too poor to exist. It had better secede out of this Union, or be merged into another which is capable of paying for work well done. Boards of health are too much limited to gathering statistics. Again, these statistics are often too much limited to those of the so- called infectious diseases. The latter class of statistics has a very subordinate value. It matters but little whether one thousand or ten thousand men perish from a given infectious disease, so long as the cause is present, yet unknown, and prevention thus far impos- sible. It is far more necessary that observations and experiments in these two directions be made than that exact statistics be gathered annually. Statistics as to causal influences, however, can never be too highly appreciated. These accumulated statistics have one good purpose : without them, in this country, it would be impossible to get means enough from the Legislatures to carry on the necessary studies and experiments by which we may in the end hope to find means of prevention. Boards of health should always have the necessary means to carry on an experiment station, and to amply reward specialists for experimental researches in any desired direction. There is, however, another form of statistics, the careful collec- tion of which would send a thrill of horror over the human family, and it is from this form that we may, in the distant future, expect very valuable results. To obtain them we need far better practi- tioners, much less prejudiced thinkers, than we at present have in the medical profession. I allude to statistics with regard to the really preventable dis- eases of life ; the diseases due to ignorance, not only on the part of the diseased, but of practitioners as well. An ignorance of duty with reference to the latter, for the medical adviser who treats only is simply fit for confinement among idiots. I allude further to the diseases due to the ignorance of the people in the employment of quacks, and further to the still more to be condemned American craze, the use of those disgi'aces of our civilization, legalised patent A NATIONAL VETEUINAUV POLICE SYSTEM. 3S9 life-dist/'ot/ers, discoveries of the devil ur his agents^patent medi- cines. Another disease wliieli requires statistical attention is tubercular consumption. It kills more jK'ople in ten years than any invasive disease of the present day is likely to do. Our climate has been made to play a much too important part among the causes of this disease. Climate, employment, etc., all play the sufficient or pro- ducing causes, but very seldom the primary cause. The primary cause is to be sought in the senseless inbreeding of weak lungs from genenition to generation among human beings, until at j)res(jnt tlie very irritation of normal breathing is often sufficient to send a child into an early grave from tubercular consumption. The medical profession acknowledge the iulluences of our climate. Perhaps they can see the other also. But truth is ever unpleasant ; and to tell parents that their children dare not marry at all, or dare not inter- marry— to tell young lovei-s they dare not marry, because they Would condemn their children to an early grave — would seriously interfere with one's yearly income. TF/zo of the medical prof ession stands up as a man of truth and proclaims to th