TREATMENT IN CASES OF POISONING 453 Water containing 40 grains of sodium chloride to the pint and sweetened with glucose should be given frequently by the mouth, if fere is dehydration owing to intense vomiting or diarrhoea. If water cannot be retained by the mouth, an enema of two pints of warm normal saline should be adnMstered. In severe cases it is advisable to administer intravenously normal saline particularly by the drip method. It also dilutes the poison in the blood and promotes its elimination from the system, especially by the kidneys. Respiratory failure should be treated by intravenous or hypodermic injection of nikethamide (coramine), the hypodermic injection of atropine or strychnine, by artificial respiration and by the inhalation of oxygen, Coma should be treated by the hypodermic injection of} grain of strychnine, by the intravenous or intramuscuk injection of 5 to 15 cc. of a 25 per cent solution of nikethamide (coramine) and by lumbar puncture. In a case where coma is prolonged, an intravenous injection of normal saline may be administered continuously by the drip method. Convulsions should be controlled by chloroform or by a drug belonging to the barbituric acid group. Appropriate treatment will be necessary for remote effects of poisons, such as ulceration or contracting cicatrices after corrosive poisoning and neuritis after chronic arsenic poisoning.