ATROPA BELLADONNA 679 4. Datura administered for Robbery.—(a) A Brahmin was sentenced to nve years' rigorous imprisonment under section 328, I.P.C., for administering datura in cooked puries and potatoes to not less than nine persons of a family residing at Nimsar. All of them were taken ill and were unconscious, but recovered in three days.—hid. Dailv Teleg., Aug. 10, 1923. (b) Four persons from Roorkee went to Hardwar to take a bath in the Ganges. One of them met a Sadhu who gave him some chapati and rice mixed with datura powder. Soon afterwards he became unconscious and the Sadhu took away his purse containing about 20 rupees. He was later arrested, and a phial containing datura powder was recovered from him.—U.P. Chem. Examiner's Ann. Rep., 1946. (c) A man and his brother went one evening with two strangers to a temple near their village to excavate a treasure said to have been buried in the temple. The strangers gave each of the brothers a cup of "Panakum" (water sweetened with jaggery) and arrack mixed with some powder of datura seeds, and then began chanting " mantrams ". Both the brothers became unconscious after a short time, when the strangers left the temple with a gold ring and one hundred rupees belonging to the brothers on the pretext of immersing the deity in a neighbouring rivulet. One of the brothers died and the other recovered.—Madras Chem. Examiner's Ann. Rep., 1949. ATROPA BELLADONNA (DEADLY NIGHT-SHADE) & This plant belongs to N.O. Solanacese, and grows wildly in England near villages or on ruins and abundantly in India in the Himalayan ranges at an altitude of 6,000 to 12,000 feet above the sea level. Atropa Lutescens is often used as a substitute for Belladonna plant. All parts of these plants, viz. the leaves, berries and root, are poisonous. They contain three alkaloids, atropine, hyoscyamine and belladonine, but the most important of them is atr opine. Atropine, Ci7HoBO;$N, crystallizes in odourless and colourless, prismatic needles, and has a bitter taste. It is sparingly soluble in water (1 in 500), but freely in ether, alcohol and chloroform. Its aqueous solution has an alkaline reaction, and is readily decomposed by keeping. It can be chemi- cally split up by strong acids and alkalies into tropine and tropic acid, and may be reconstructed synthetically from these substances. The non-official dose of atropine is 1/240 to 1/60 grain. Atropine sulphate (Atropince sulphas) is an official preparation, the dose being 1/240 to 1/60 grain, It is odourless and occurs as colourless crystals or as a white powder, and is soluble in water and in alcohol. The following are the pharmacopceial preparations of belladonna: — 1. Belladonnas Folium.—Belladonna leaf. It must not yield less than 0,3 per cent of the alkaloids. 2. Belladonna Proaparaia (Pulvis Belladonna).—Powdered belladonna leaf. Dose, J to 3 grains. 3. Extractum Belladonnas Siccum.—It contains 1 per cent of the alkaloids. Dose, J to 1 grain, 4. Tinctura Belladonnas.—It contains 0.03 per cent of the alkaloids. Dose, 5 to 15 minims. 5. Belladonna Radix.—Belladonna root 6. Belladonna Radicis Pulvis.—Powdered belladonna root. It is grey to light brown in colour. „ 7. Extractum Belladonnas Liquidum.—It contains 0.75 per cent of the alkaloids of the root. 8. Linimentum Belladonnas.—It contains 0.375 per cent of the alkaloids of bella- donna root, 9. Suppositoria Belladonnas.—Each contains 1/60 grain of the alkaloids. The following official preparations are derived from, atropine sulphate : — 1. Injectio Atropinos Sulphatis.—Strength, 1/100 grain of atropine sulphate in 15 minims of sterilized water. Dose, 1/240 to 1/60 grain by subcutaneous injection. 2, Injectio Morphines et Atropiuoe.—Strength, 1/100 grain of atropine sulphate and about 1/6 grain of morphine sulphate in 15 minims of sterile water. Dose, 8 to 15 minims by subcutaneous injection.