NERIUM ODORUM 717 by Hindu worshippers. It has lanceolate leaves and has a two follicled fruit which contains numerous seeds. All parts of the plant are poisonous. S. R. Naidu and his co-workers 21 have isolated from the plant an active principle, nerin, (Ca5H3oO10), which is a pure, white, crystalline glycoside. It is sparingly soluble in water, ether, petroleum ether and benzene, but dissolves readily in alcohol, acetone and Fig. 195.ŚNerium Odorum. chloroform, and melts at 123░C, It is highly poisonous, and when injected into the dprsal lymph sac of a frog, it produces paralysis and death. The average minimum fatal dose for a frog weighing about 10 grammes is one- fiftieth of a milligramme. Eight milligrammes injected into the abdomen of 21. Madras Chem. Examiner's Annual Rep., 1937, p. 8; Jottr. and Proceedings of Institution oj Chemists (India), Vol. XV, Dec. 1943, pp. 134-144.