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YELL OW FE VER.                        407

ach and intestines, where it develops. It is only excep-
tionally and in small numbers that it makes its way from
these positions to other organs. He thinks the toxic sub-
stances formed in the stomach and intestine are probably
the result of the breaking down of the bodies of the ba-
cilli by the digestive juices, and that to the absorption of
these the various tissue-changes and fatal terminations
are to be referred.

In a lengthy and interesting review and comparison of
Sanarelli's and his own work, Sternberg1 concludes that
the Bacillus icteroides of Sanarelli is identical with the
Bacillus x, which he had discovered in yellow fever
cadavers as early as 1888, and felt disposed to describe as
the specific cause of the disease, except for a few facts,
such as finding it in only one-half of the cases, etc.
Sternberg seems inclined to believe in Sanarelli's work,
and asserts his intention to further investigate Bacillus x.
Bacillus .ir was, however, isolated from the alimentary
canal, in which Sanarelli's bacillus is said not to exist,
and was isolated from the liver of a case of tuberculosis,
wliicli takes away considerable of the evidence of its

In a later paper2 Sanarelli discusses the validity of
Sternberg's claim to priority of discovery, and points out
a sufficient number of differences in the original descrip-
tions of the organisms to establish conclusively the in-
dividuality of the Bacillus icteroides.

It would seem, from a careful consideration of the
recent literature, that Havelburg had very little ground
for considering his bacillus specific, and that it is not
possible for Sternberg to establish the identity of the
Bacillus x with the Bacillus icteroides, while at the same
time Sanarelli's descriptions arid arguments are convinc-
ingly in favor of the accuracy of his own work and the
specificity of his bacillus.

1  CentraWL fi'tr Bakt. und Parasitcnk^ Sept. 6,  1897, Bd. xxii., Nos. 6
and 7.

2  //>/</., Htl. xxii., Nos. 22 and 23, p. 668.