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408                PATHOGENIC BACTERIA.

Sanarelli's labors have not ceased with his careful study
of the Bacillus icteroides, but have been carried into the
important field of serum-therapy. By careful manipula-
tion he has succeeded in immunizing the horse and ox to
large doses of the bacillus, injecting into a vein so as to
prevent the intense local reaction, and has found that the
serum of these animals has the power to protect guinea-
pigs from lethal doses of the bacillus. He hopes that
the serum will also be efficacious in the treatment of yel-
low fever in the human being.