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6000371 73R 

1512- ^,- '^ 


r . 


I , 


O N 


By R. J A M E S, M. D. 

Solet autem ex eo vulnere, ubi parum occurfiim eft 
aquse timor nafci, 'v^^o^oQiw Graeci appellant : Miferri- 
mum genus mcibi : in quo fimul aeger et fiti et aquae 
metu cruciatur ; quo oppreffis in angufto fpes eft. 

Celsus. L. 5. C. 27. 

t|»ooeo c oopoc{ i oo«ooopoQOio rm iioo oBn ( i oopQo nnninipcn o B o >WBD Oo9 B opooMo< 


Printed for J. N e w b e r y, at the Bible and Sun in St. 

Paul's Charch-yard« 


y^ < : 

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Jti*- ■■.. 

^ l->.^( 

.' i 


.'^rn ' ■ i- •"-■ 

. 'it-y ■' 

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Baron Pierrepont, of Holme Pierrepoht, 

. Lieutenant General of his M^efty's Forces^ 


^night of the Molt Noble Order of the Gartcri 

My LoRjj, 

ADDRESSES of this kind to per* 
fonages of diflinguidied ranky 
are the more difBcultj as from time 
immemorial they have turned upoQ 


a i>B D re A^ir voim 

ptancgyric, as nearly allied to flattery, 
a$.|!at;teryis to falfliood. 

ov--.- ■ ■ " ■ 

.,r rXHpsB^, howi^er, l (hall ende^^ 
vour to avoid ; becaufe the one is as- 
fatal to delicacy, as the other is to 
^onow a^d innocenpe. . . 

J^ WjpAT ijQicreafes. the diftrefs isj 
t]^^^>fe'ry excellerice a perfon is re- 
£i)Jj^.)ij;i .ppfieflion, pf, eeafes to be 
l}^^ , Qbje<£t ^ pf Jiii« ,apit)itipn, a$ it . is 
^^jK^iJiacif^ by, habit ; fo that 
^me' imaginary virtue muft be 
f(^jfffy^i which i^ fur« ,to havp a better 
ej^e^,.as i^carr^s .^he .appearaiice. of 
^i4\fm^^A'-^ ^^s the.-pkafijr^ 

^f I was 

I was therefore to fiiid out st psi* 
tron, who neither wanted, nor ex- 
peded, this Ipecies of incenfe ; who 
had rather do a thovrfand worthy 
adi(»i$, than be told of one. 

Amongst the cardinal virt6fe^, 
my Lord, there is one which docs 
honour to human nature. It is^ 
undoubtedly, the gift of heaven; 
an emanation from, the Supreme Be^ 
ing ; becaufe it can never bfe acqui- 
red, though it may be diilcmbled. 
Where poflefied, it adds luftre t6 
crowns, and dignity to titles. With-^ 
out it, royalty is tyranny j power, 
oppreffion ; and juftrcc xmieJty, 
Without it, even virtue and re^ioA 


if 0E Die ATI OK. 

contract a morofenefs^ nearly D€»der- 
i^:Qn,inaligmty:, , ; ., 

I ■ , • • ■■ • I 

,j(>| wEiED not tell jx)ut>Gr2cej that 
I[;qaean good-natucd, humanity,: > or 
thftt univeifal benevolence^ which is 
%<>i]tr(M>glDr. reeommended in Scrip- 
twp uijder the, name of Charity. ^ 

iwiTHJs.I think mtieL' too limited, iF 
e<DBi^nffd tb the human race. As it is^ 
a^^ee glft^ ^nd inesrhauiftibk, it fhould^ 
be as freely difpenfed ; and the brute 
creation has a right to a ihare of it< 

i'Thmv mjr^Lotdj I may Ikrely 
afctibe 'td' jrdut ^Grace, without de-^ 

lilatihg'^cbi 'niy owTi* rules. And I ■ 

vo .; ^f! . 1 ; ' . flatter 



..: o I 1 / "^ T CI :•! a VI 



Hatter myfelf, you will baVe* ibiiiid^t 

materials in the following flieets, for 

. the exercife of this i^irtiite ; wheri fan 

iliall find, that GANiNEM'A'DNfessatd^ 
mits of a remedy y- though, till fonife 
of the firft of thefe experiments were* 
made, ^ from ^ the infancy of phyfitf/ 
very few inftances of recovery have 
been recorded, ' after ' thie infection 
had made^fiifficient.progrefs .to^arnHf 
&p^tMt^,evcjx}k^vQiy ;firft a|)pearaDcfes: 
of ^- diften^pef . i.w ..?.;! ^i- jt! / ^ai 

A FARTHER fatisfa(3:ion, my Lord,, 
will arife ffom refle^ing, that; |the 
grateful, honeft, and ■ fcnliWe ,, i^nih; 
^aJ, Y^hich .is .par^y thC: , fubj^ ,pf/ 
this^Xreatife, will, for the future, be 
iefs liable to the wanton perfecutions 


» —IV ^ 

\- ' 3t DT CATION. 


of \tlieir torturers, who, was it net 
for the rcftraint of laws, would treat 
dieir own fpecies with equal bar- 

I ajn, My Lord, 

•f * 

With tfie utmoft Deference, 

55Qur Griace's rhoft obliged, 

.1 - r'.- * « 

'. I ^ - - - • 

; . 

'ariS',moft, obedient 

ii'J.x ,-■ 

. .. J . .Humble Seirant, 

•••«• ■ ' V 

• ";^ ^ Robert Ta.mes,.; 

f • ' 

vzit.. ' :.: •• . 


i • •! 

. V ; • . . . 

'C'T .• . ■!:; 

■ ^ /.. 


^:tJ;i€K I N E MA p ^TE.S S. 

#t ■ ■■ r I 

H E diftcmper excited by jthic 

bite <)f mad animals is ufually 

called HydropbolMf from a re- 

mark^ble fyo>ptpai g^rally^ 

but f\o.t,2dways, ^a it, which is a 

drealJ of water, or any liquid, and an 

abfolute inability to fwallow a drop of 

iL It is derived from two Greek words, 

I one of wjhich. in^rts water 9 and the 

other, y^tfr. But the fymptom is not 

' peculiar to the ^diftemper abovemention'd, 

/though it is generally an attendant ; for 

B we 

^■^ Hi* with fevrfa .inftafices'efan|r» 
^icbihifiiiiiea with i'ateid'of'WWi'i /(aid , 
when he quotes Hippocratei, as mention- 
ing this Ipecies of madnefs. The place he 
alludes to is in the firft book of the Pror- 
fjf^iian(lruns51ius/t?i ^/p^TtxoifPf«x1J»r 

TOt, ■^Q^a xmi»if[ifttvatt r^ojjtuSus. Xhls IS again 

repeated in the C^f^ Pramtioneit thus. 

oilly, as (j<«?» ejf plains It, thofe who in 
fevers drink very feldoni> and theix.hut.ill 
"/feaU ^iiaAtes>' !'ARd;i)jJ'tl\e VtrhiJo, jrf- 


•*'«?«! iH-im^^ tk^iiiii ate affefted 
VitK'^kiy iJiatfteSbv'We'fubjsa'^io %. 
%ti«n*i;'(Sik»^s? - ' ' " '' ■ ■■ 

.1' -KKir-I' itMiiber, ■ ^ii'^ificra^, 
'-'i<me*heh?irfhiSt)^i2dihiis;'(ift's tii'c*i^ 

^- ^: by 

A i. J 

_ { • f 

ly < f '# ^^»v— ^,-'W TV' '■~T"»"*'*' '^ ~ /"^- • ^ ~''»rW»5/T;'5 . t r ,■ -./..-. 

1 • f . • • • 

five fits, upon ende^ivouring to drink pr 
b»liWJ£"»bing. (TQV^^dsr:,^eTei|d:p£ the 

iiiiea.-^uart^r -pC^m hmt*^)»^nu to^ fp(iSik, 

B 2 and^ 

artdi ^ith her finger, pointed to the paft 
afFeifted, which was under the upper 
part of the fternum, where it is joined 
with the clavicles. About two months 
before, ihc had a quinfey, with a violent 
fever ; and, when it was expcfted every 
minute that fhe would be fuffocated, the 
fweiling abotit her throat fuddenly dif- 
appearing, fhe was relieved in a great 
" meafure j but was fenfible of a painful 
WCTght remaining in her breaft, at the 

- place (he pointed at ; and from that 
time* deglutition had met with fome ob- 
flacle, which- had daily grown worfe. 
About three days after the Do(Sor had 
feen her, a tumor broke, which almoft 
fuffcicated the girl witli the flench aiid, 

- quantity of; matter, and- fhe recovered. 

*"^ Very -rtmarkable is the cafe quoted 
<%y Vm SibleCen, from the Mifceltan. Cu- 
nio/^of a^man about thirty-nine years of 
age, who in a great paflion of anger, bit 
his own fore finger, in confequence of 
which he was, in twenty-four hours, 
.; . - feizcd 


.fed; with an Hydro^bpbta^V^iox^:^, ^p^, 
jfie^x/ythat-lie.feemcd iSm^^ ftrai^^jal? 
'tlie'inention of wateri- and ibon, after d^ed 
Wfng, ,And it:is,>flotMjnlikp|jrt,tha^ 
¥«^':ftom, j^nr: W0UI4. .ha^-.jEsD3d«Jic^ 
.Hydrophobia in another, . ^ ;,;>[,? :/jn?Qbi 

/ . . 

•fi^i^i^^^i^^, gives a reotarka^Ie ^pa^^^f^ 
a^,j&5?</r<?/>i$o4*i^ which J 4f>n't W pr^ 
tttlded from the ■ |)i|e of a. fla(94 4ogi XlXi^ 
^Ijas ii>a-.yoUog gendeinaf>if:whQ YE«^§>J«i2b 
ed with a violent paifi at, /y|u| upper ftf^ 
^e pf the fton^ach ; .his {HliUb^Was.mvdli 
<^r'eired, and very ir^egulaiv and pfttq 
intermitting^ and his ex(^fpi|tipe)ClBlV<l£ 
Ifje was alnaoft fiif&cated^ /^tct^ng heav^ 
fig^, an^ yery ofteq lopkiiigt; ghafttjrjr 
fpputingout faliva frequently. ' In hjs Lir 
t^rvals he would; calif j[qf44^ I ^^^ ^^ 
l^$>men.t he.faw^itii^U.iAto^^Q mof^ fuf^ 
^rifepg hdrrprai.;.;and« a». jHHiipptoaAhod; 

fe»mi,.ftartediJ.9ol|ed; ffigbtirf, fcfeid /con-, 
vt^^nsk efpecta%: ahovi^ th9(j<n«Qth, and' 
peifivifhly pufcit ftw^ vi^^ Jjii^ vhan^ . 

B 3 and 

^ *■ V 

8 \f'V¥t\fi^'<!M'' 

Sn& riiferii'-wHth an air thht fpokeat'oriW 
Botfi 'fright 'and refefltmenf, he woultf 
ftart after this drink, and fodn aftet*, 
in^a^ently call' f6t it, and repeated tht? 
fifcne Icerfe'Preqiieiitly. HfeAras-curftd'-by' 
repeated bleeding. 

^■'BtrT a^ nsSte I'eceAt ihftance to 6ur 
f*e^ftt purpbfe'Wjfs comwftiaicated to me 
by Dt". napStboy,' <^ Wdirt irt tmcok- 
fiitriy fix^ aftet' if feappert'd. WHtiam 
Goodacm iert'arit to Sdy/iuet Baftmood^ 
l5cK*tor of liaw^S of fP'^lTftit ii* Li^olk^ 
jkiferWM^y^Bttt^. the i^t\ of March* 
tf$f, vfSs -feiKed \'Hth »he' frfiaVt poX, of 
a'-vei'y flrtiia jfnd faVohraWe fort, wPiicfe 
Kffhdd the 'ftVcrith day after the 6i-iip- 
iibti, ahd'^trent off in the rtoft dcfkrtibld 
mrfnfiet. B(it EibOUt the f^cnd day affiaf- 
fhB iydp*iort; he was fei^Jfid With a delP 
ritffn, dt' phf6Tity, whfellafol^ tO fuob 
^^height,'»hit he ftaiVierf Kt !he mowh, 
rrfilfed i\l IH^iior, ((rid''*rtdeavoiired to 
ttitt the attendshts. Til^ made two emi- 
tveht' ]bhyf^'iartB that attahAid him fufq 
%ii i -'. pea. 

<=mmx¥i^M^^k- ^ 



of a mad. doe:. For this reafon they en*, 
deavoured to give nim the 'Tonqum re- 

When the fmall pox was, entirely over, 

powders having no vjifiWe opa^itipn. ,he 
took another Avhole paper two hours after 

^^ec^^ th? far?)^,.^ay :^ .t% .ja^ei; J^q- 

^l^u^h?lf ap h»p,i-,,o^pr|te4^^jP^ij|:gip§; 
hw r^ykjg^ afl;9r. tbjs^ gj-^w^jci^vJ^c^^A^ 
ipfi' J|i^. qat and drank any thing ihey gave 
him. He continued taking the powders 
three times a (lay;;for three of )f(Hir days, 
aftef ivhichj the i:ata,plafih)5'or3<5i^d in the 
V - B 4 V flirectj^ons 

^ireftidns for taking thefe powders/ i^fefc- 
applied to his feet, as alfo a blifter to his' 
head J and upon taking the powders twice 
a day for a week more, he perfeflly reco- 
vered hoth his fenfes and his health. ■ 

" J&oci'dR Dajhwood efteeming this ciiffc 
worthy the notice" of the public, 'othtfit 
it to be inferted in the public papers, 1753. 
Upon enquiry T could not dilcover the 
leaft reafon to believe this Hydroplkbiavii£'\ 
caufed by the bite of a mad animal, 
dp I know that my ^bwders "would ha* 
fcurdd hini in that c^dfe. " - - ' 

CiriFtfi" JtunltaWf^teim^ to have^bs^J 
fenfible, that an i^S-^'^hobht was niSi 
peculiar tfl"the diftemper e>:cited by^llie 
bite of a tflad animal, when he fays "that 
"■'tispoflible for this pafTion (an Hydro- 
to be produced in the body 
*' without 

* £11 prxt«rea poi£b lie. fine QiaDifcita csufa haifc 
palltonem corporibus Innafci, cum talis fi-rctit (Itic- 
lioJfOnte gencrata, qualfs a vejieaoi 
^'Ui^-r ^'-^ Ctelius AurtUanus, Lib. 3. Acut. C. 5. 

-< • 


« without a ms^iiifbft c^LUTe (at>ite-][*WH^ 
<*fuch iftriaufe fti is ohSiwt&' ffom' 
«* ppifcn; is fpofttaiyioiifly geQcr^tecf/*; -^^ 

. , * 

Thee* cafes, tO" which' iritoy^otlw/ 
might be added> may ferveto prove, that 
m ^]Sy'Ar^bobia '* may \>t ■ gener^ed jHrom 
QiMiite WdBpenderft 6f the hitfe t)ra'tiia^ 
juiimal.; On. th^ dthfef hifid &A$Ma!(i ht(t 
unfr^uenfly^ die*inad iii ajiifcqueiicc 6f 
H bite from another mad ahimaT, wiiliout 
any figns of terror at the nght 6f ;ap- 
proSCh ot water. I have frieqflteftdiyVfliii 
toad dogs, all of which refufed both: to 
drink and to eat ; but I never obferved 
any emotion or figns of dread at the^ap- 
proach of wiater, or any other liqmd 
ioiffered them. On the contrary^ libavts 
ieen a dog extremely ravings fhatch^ti 
veffcl full cf milk from a pcrfon's- hand, 
m fuch a manner that part of tlftf:'thi]k 
})a^ been in his mouth, and about his 
jaws. And I have alfo feen a mad dog in 
■his foiit traverfe Water, not f6ttg before 
he died. I within thefe two' years, faw 
* • a young 

ip A^ TiR,5i A T.I S E, ON. 

by tli^ llite of, a, ,mad 4og, Ayh'o i(i; iriy, 
pr^f^Bce dranK a' glais of wiater/ and iii a 

water, attendin&r -it. ^His circumfbirbce 

f!L^^^Wr<?$^<^¥^^.k dr« y^t^t*.,^? 

tfi/i p^i;petvi4 coiji,c,Qnxi^^t of; jEbki .|iiit^ 
tfiqigpr J.; ;fctf: tJbi? ^fa^M Jjbfl^e i^pi . ottf^ofT 

^4HP4. :^o be^eve ^t ftf|t fjiaj^, ^ !?y ,- i^ 
means .'(aqtb tbefla^^ve^ into, a: f^^tal i^r 

. , . ...... . . 

Bsf«>|i4 I prpG^pd %ther, I mufl takp 
poti^^,: th^t I aei in^oifued by a letter 
from CqIorc) J|4«^f//t ^i-^nfWt a genj- 


cab d£|)mullup£si^.ilifft: no'rfgygliji 
dung a$ ^ihadidog wa^ eycai k!)<lfKQlr^ 
tAmLeewsrd:iOaaQdia« Ami:l£i9 ^(miitRMn 

Ra^knnek, . which: is, that^tlkefie k iio fv9^ 

• ^ . • ♦ • r •'•■•#,' 

r^-zls. r\^ •» .•» - : rf.. „,. k- I »~»^. •.V^lib. 

wfifc- ferae [Wry cjxtraQ^dwx^ c^fOtti^ 
ifetiwes^ bi^fe thefe ham l»eea mudltijpU^ 
and magnified bieyociid 9i^ yferi^^Hd^ 
and beyond all the limits of truth, as wiU 
be ihewn in the fcqndL This ia vkry 
nfoal liipoQ many other ful^^. A. pftfti. 
ficii for the inarvelbus, and an itc|x 'fer 
rd^ating uncommon ocicurrences; baV« 
freqaenify'laid a. fonndatioe ibr miftabc^r 
cxaggtration> deceit^, and falfliiood.^^ \\-'^. 

But ;t<> proceed, great difputes- hav« 

afoie concerning the antiquity of thc^jS^ 

df&phobia *y -and Piutdrch -is quoted- <b^ 

ibme, particularly Le CS^r^^'^ alkdgkf^j 

: fi '^ that 


riiat it firft appeared in the days of Af~- 
ckpiades : But this 15 a miftake, for Plu^i 
tarch only relates a difputc between P^r/« 
the phyfician, and Diogenianus, whether' 
liaUirc could produce new diftempers, or 
not. Athenodorus is quoted, who fays;, 
that the Ekpbantiajis and Hydropbd'i 
bia both firft appeared in the time oi A/-* 
ciepiades. Diogenianus anfwers, as to this 
particular, that the Hydrophobia was 
known to Homer. Plutarch never denies 
this, bot endeavours to prove, that new 
difcafcs may be produced. 

Ctelius Aurel'mnus, in order to prove 
the antiquity of tliis diilcraper, quotes a 
paffage out of theeigthth Iliad oi Homer, 
where Teuccr calls HeBor wva. KiwatiTnpa. -, 
tho' he docs not feem to depend much 
upon it. He has, however, omitted fome 
other paffages in the fame author, which 
are, in my opinion, more for his purpofe, 
and come fully up to the point. Thus, 
in the ninth Iliads the artful lJly(}es is \x\~ 
iroduccd addrelBng jArA/y/e-j, a hero who 


had made phyfic a p^ of his ihidies, in 
thefe wordsi ,:>. 

In the the thirteefiih' iZrW, He&or~Ji 
' again called xwmdi^i By JSTeptune: 

\ ' ' • • .... 

V i It frioft be obferrtdi diat x^trat, xvtin^ 

--afld AvWMf^i ptc>{i6rly idifdy this.pittjsgiiitf 

•^ i^^ecies bf madttefii The wwd ^iritt^^ 

' Avi1«; is - 11^^ to fignify the madnefsi bf 

« dogs by 'Arijiotief Gakn, and jD^^rfti&b. 

And Auwlptt^ is ufed by thelaft mention'^ 

author to fignify a man bit by a mad dog. 

xvtnrdai is ofed by Aretatis in this fehfe^ 

and xwmJtfiff by Phturch to fignify ^ 

. iame thing. 

; TMr>.fliJtnnp€r I ain Jtrciiting of is jn 
maa^. gntfraUy . css^^^ t^ bitci of 
ibme animal prcviouily mad» and. ptic^ 
cipdly from domeflic 'animals^ whifii 
have th<;.^greatefl: commerce ^wiliiiiftaiQh- 
' * 1 ; ;:apd amongft , dQ^> : ^o^: )catsj 

* fwine. 

^4 ^A'TKEATrSE ;OfN' 
■fiffiHe, -Kories, and even cocks, arci/ad- 
cufed.' I believe it may be poffible for 
a cock bit by a mad animal to.contradl 
the ' diftemper, and communicate it to 
mtn-by ;pecking him, fo as to. penetrate 
beyosd the external ikio, or cuticle. But 
that a wound with the fpurs of a cock, 
Or the horns of a beaft, is capable of pro- 
ducing -tfais diAemper, as is related by 
■authors of fomeweight, and as is com- 
■monJy believed,!!' think highJy imppoba- 
■■fele. lit has alfo been faid.i that even the 

■ Wood of -a mad dog- applied' to the ikio, 
' or (ouchiog the froth emitted from the 

■ "anouah of antad animal, will convey the 
-^^mper. Bat as many people have 
=eVen -eat «he liver &f a mad dog hy ■ w«y 

of medicine, and confequently ■ the bile, 
without any injury, I think the blood is 
.hot likely to prMiice this effeiSl. I- was 
many years ago confulred fbra'iervant of 
'Mr. Hor/fcn's.'of CUfton^ ut&v' Litvhfiey. 
''This than killed-amsd flog b>r3bloW-fo 
" Violent, that he received a - confidcrable 
' quanlitj- of blood in" his'mouth-'from the 
^-^^ — ^-^ wound 

V. /-N 


f 9 . • • 

"wpuh'd ne • gave the dbg. I gave it rffi 
my^pTiii^^^ \W tfie'infeaion- Could ti6t 
Kf propagated tiiat way, and'I ido not reSr 
niQmber . tUat he took &ny pfe^atiflo^. 
Tiie event vermed jcny. prediction, for I 
law nun perfeiStly well lome years arter, 
when ^ I .was informed no lymptpms-OT 
.niaanels Iiad ever appeared. I have 
,Known. many people, one particularly, a 
'whipper-in' to TVIrJjF%yi?f^8 fox-hounds, 
"at j9/«/j^ in *S4'<2^?r^/r(f,'who'6avc'.b* 
daring /E^nough to-6pen the jav^^s of a 
'dog 'foinqiBfy, ' when * a<3;ually ' mad, and 
'drciich' Kim,* without any fiipervenihg 'ac- 
cident: But I. am credibly informed, 
that "others,, who have tried /the fame 

» » • t r 

*expferTment, have fared much wbrfc; fo 
that ^tis* much better 'to Wold fuch fa- 

V' A«*^ •* W-* « 

inilTafity, as ^tis*^ certainly attended with 
much danger. 

< -i- 

■ ' G-^ • -^ Jk 

T^PEJiE ire' other ways of receiviinfg 
the'^inireiSib^ very extrab^^ 

j^irv^^ attieftcd. 



^ Pel 


Paimarius, cf a man labouring luider this 
diftemper, who, after moft earnefUy m- 
treating permiffion to Jcifs his children 
before he died, was fuffered to do itj 
and in confequence of this, in feven days 
all his children fell ill of the fame diilem- 
per, and died. In this cafe 'tis very pofll- 
ble, that fome of the frothy faliva might 
be conveyed to the lips or the mouth of 
the children, which not being defended 
by the cuticle, might communicate the 
contagion, as it happens with refpeft to 
the venereal poifon. It is, farther, faid, 
that the breath of a mad animal received 
into the Lungs of another, will produce 
the Hydrophobia. But I cannot confider 
this capable, of conveying the contagion, 
as I have feen people very often, for many 
minutes together, hold their mouths fo 
near that of a mad dog, that it was 
impoflible for them to avoid taking 
* in their breath at every infplration, and 
yet "no madneft enfued. I think, How- 
j^er* inad dogs very difagreeable compa- 
t ntonsi and would by no means reconi- 
. '■ mend 

mend their company to others, Ccelkis 
Aumlianus mentions a woman^ whofe 
gown was torn Ijy a mad dojg^« and whp» 
upon mending it, wetted ' the rent with 
her l»oguej^ ip order to ftcilitj^te $h* 
paipige of the needle. * The <cpnfequence 
was, that ^e fell into zxi Hy4r^b$^iq jia'; 
threq days. Jind Hildanus takes notice 
of another woQiaq, who ^wine; a rerit of 
her garii^nt, torn by a mad dog, bit o^ 
the thri^di and threp months after died 
of an Hydropffo^. Thefe are extraordi-r . 
nary occurrences^ .which have inc^ned t 
ibme to iQ^agine, that toiiching the froth 
etnittfid.hcmf^^ would, produce 

the dift^wp^r. But I have feen^ a boy'a 5^ 
hand in, ^e. yjpffy o^^ of a^ mad d^g^^ 
hfWiipg, cypti^n hi«. j^Wf » in order, tp fprc^. 
down s^ ball, of medic^w?, by which xneaus , 
his whole hand /was cohered- with frothy* 
Md , yet |iQ wjttry.. eijfu^ed. ; But if this 
fro$h,jha4 bcj^Hf appjjiftd^ , ^o ,aajr part dc* 
mtu?e,<^ tlif- w^ifile,, I. think it .miaht. 
have jjcc^nyjeyed, ^e .coatftgi^n ; into jthfi, 

C Very 

^8 '^: tr^ E AT rSlE : 'ON 

L.i ,1. ( •..;.... I- . •• ■• ■ J ■ ' •■ 

. .Veryi rcuaarkablc is the; ftory . related 
]by ^ckenciiuh of a boy; who cleaninga 
fword iwith .which a mad dog had been 
killed, oiany years before,, unfortunately 
(p^t.hisj&ngpr, and thereby contraftedraa 
Hydrophobia. : 

,, r 5-^ «• • . -■■■ ♦ ' ' ' \ t » > : ■ 

c It has beien queftionedy whether eat^* 
iog the fieih of a mad animaU or th^ 
x^ilk/ .ca^B . iCommunicate the contagions 
The liver of :the oiad dog has frequently 
^BOejtten without injury, which fecrtis 
fe) determine the firft in the negative ; be 
that as it may, a caution againft it could 
be of ufe to none but the Cbinefe, who 
fQail upon /animals which die fpontane* 
QxtH^Y:^ dogs- not excepted. As to the lat- 
t^, I iuaow.' that tlie milk of a bitch will 
c;pjT)n[iunicate^ the ixifedion to pUppies^,^ 
Vjptkfs it :ihould rather be thought to be 
conveyed by licking them. 


;;. There is. another way by which the 

CQOtag^oa may be^ and often is, propa*^ 

'i.^.v^.yi .-. gated. 

'gated. I have the moft unqueftionable 
imlaority, thatiwhena keiYCid Has b^en 
once much infcfted by thiS refiddicb of 
WDsd dogs '^^in it^ (though aitt the ftraw fe 
biimt,' the kennd fumigsited^ dnd iaill 
methods taken to purify it, yet if ogs' will 
contract thediftemper a long time aiti* 
by lying in it. And I have heard the 
fox^thunters fay^ thaSt the only way to 
d^ftroy the contagion is to let a fiodk of 
gee^. lie in it for a confiderable timej 
Whatever efficacy this luftration may 
ha¥ie, it proves, that it is commonly 
known that kennels are infed:ed> anidf 
iiommunicate the contagion. * 

I SMALL endeavour to ibew, that this 
madnefs is nothing more than the fete^ 
cui'mvorous animals are ibbjedb to, anid 
that it is inoculated into other animals 
Aat ircoeLve it. And if fo, ddgs and 
other carnivorous animals may be infedK 
ed by effluvia only, which, with refpeft 
IQ the human %ecies»\ are innocent y in 
the^j&ni^ maROcr ^ :the finallr pox Is pro^ 
.r.a: C a pagated 


pagated from one man to another, 
which, however, dogs and other animals 
are not fufceptible. It is confirmed by 
obfervation, that we may make almoft 
any dog run mad, by keeping him fome 
time without water ; that is, give him a 
fever j especially if at the fame time his 
aliment is rancid, fait, putrid, and fetid. 
And this fort of food, together with 
want of water, a very hot climate, or 
one fubjeifled alternately to exceflive heats 
and immoderate cold ; an extremely hot 
and dry feafon long continued, and worms 
generated in the kidneys, brain, inteftines, 
and cavities of tlie nofe, are juftly ef- 
teemed the preceding caufes of madnefs 
in thefe animals. So that I fliould ap- 
prehend, that the madnefs of a dog, or 
any other carnivorous animal, is in re- 
ality nothing more than the common fe- 
*er fuch carnivorous animals are princi- 
pally fubjedt to, attended with a delirium 
in the rAving madnefs, and with a fort 
of coma in the dumh madneji, as it is 
called by the huntfmen, in which the dog 


c f Dt m ? V iw AP¥^ s ^. M 

Jles ^!»pid and as it were fer^fejpfs, tsdk^P^ 
|ip jnannerpf notice of any jb<?dy, <x ^f 
thing,, tiyjie die% never U^empung to 

r " - • 

.-- -»• . i-» ., "■ ■' 

^ ■ . • ' ■ • ' ii >' ' . ■ . > 

With refpe(3t to the propagation of 

this difleinp^r from hrulies tq man^ this 

^iibffe feems to be^ as it W£re» ioocuktcd 

hy the bite into the animal which re<- 

ccivf^ it J for it is remarkable^ that the 

wound> whereby the poifbn is received> 

grows ibrei painful^ and fometin^es fefters 

ibme little b^fort^^ or about^ the time the 

.difl;eniper begins to appear* Somethic^ 

-vierylike this happens in the Inoculation 

vof the fmall pox ; for the incifions^ ^bpre 

the variolous matter had been introduced^ 

.begin to grow fore and pain&l about the 

timeb*the diilemper begins to £he w itfelf. 

If it fhould be afk'd, why thofe fevers 

which the human fpecies is fubjedt to 

vare.not propagated in the £une manner 

. Jby inoculation, I anfwer, that the natural 

weapon a dog defends himfdt with from 

his enemy, or what .he efteems. as fvch, 

'"'-■■ C 3 is 


is his teeth J that of mankind, the fift. 
When a iog, therefore/ of any other car- 
nivorous animal in a delirium pic^s 1 
quarrel with any thing he imagines of- 
fends him, he bites his antagonift, and 
fbme ro£tlf£e iaUva enters by the wound, 
or fcratch> a very little of which is fuffi- 
feietit to excrtfc the fame diftemper iq^t^e 
^bunded animal. A man in thenfante 
-fituatibn gives a flap on the face, a box 
bh the ear, or a piiich, by which no 
^uhd is made, and hone of the excrei* 
jlifcnthious Juites difcharged from the fick 
jptfrfon'Ts conveyed into the habit. But 
rthfere arcTotne inftances of contagion be- 
ing propagated' by ail accidental wound, 
4nade by a fharp inftrument, when fomfe 
•excrementitioiis juices from a morbid 
hfaHy have been i incatitioufly appfifed to 
the wounded 'part, isind'fomerimfes even 
.by the'bite'of a perfoTi in afevdr, where 
there wa$ ho fufpicion of the canitie 
madncfs/ of ^ which iet the following 
cafe fttit to 'me fot my dpimonv be an 
evidence, ■ '* -J * *'' • i ' ' ? 

-' '^ To 

C *• N I If ei JV$.A,Q^ ^S. ^ 

The following cafe is iubmitted to yoiH 
for your opinion and dircfiions* J : 

* ( 

j^'G;ef^0e|?^?«^aii who ai;teade4 a^^^a^ 
of quality in JamJ^fj^. ][^; W^ 
unfortunately bit by her, when fhe w^ 
in a frenfy, in the extreme_|puit .qf J^pf 
little finger, wljich j uft ^ ^reiij/ ^Go4- 
Pain and inflai?jnj^tio» eqfqed^ap^^a^ffj;- 
tle^ turpj?ntine ■ was applied to the par^ 
5ut the furgeon could not keep the /Woun^ 
from healing, , ^d . fkipning. .o.yer, v,^ 
foon. . ,, , , v^ 

'/i.r ^^r^: /^; 

TwE inflammation upon the joipt,. ner 
verthelefs* continued for fome Av^eks ,af- 
ter.. , Thre? d^ys aft^i: the bite^^ ihf; w^ 
blj^d, and topk a purge* About . a w(?e^ 
after tjaat, fhe was fei^ed with a fpittipg 
9^H>iich froth, a. J[yn}pton(i, , th^t attended 
the lady quite through herillnefs.. This 
Y C 4 fpitting 

(pitting con tinued^ bating a ihort intfeN 
valj for a coh^fabfe tittle 5 afeverft^- 
lowed it ; the inflammation on the finger 
xncreafed. " ' '- 

Upon this a blifler was laid oil one 
arm, which difcharged copioufly for a 
ibrtni^t J krt it v^& ittelld6d with a 
H^ inflanithatbn . 


AiHp6*t!ie bliftef dried; flxe was Med 
^ipkii ahd tbok another dofe df phyfic t 
Slid in two or three days after, the «*n 
grew itic(re inflamed, dnd there (hot thro^ 
it violent darting painis, the fame as in 
ttie fiirgel-; ahd ^efe pains iafted, as 
long as the fever fits, which continued 
about twelve hours. 

. » V 

Upon this the gentiewomaft took to 
her bed, and determined to try your 

The firft doie tvas half a paper, which 
gave two or three gentle pukes^ brought 

V. :' off 

off a pretty deal of difcok>« 
produced a copiOttS fwAtt fyr^ dj|^tt or 
nine hpufs» and majiy faolU ^raptioits 
and efflorefcences appeared onftibc^bioii 
which (Welled in, die &ce and handSf 
and "Other parts* :. : ' 

Upon the ceffidon of thet Atircit» ifi« 
fever returned, and ihe took the £urie 
dbCt as befcHce, on the fecond day ; which 
rta6wed the (Vreat, and kepf di» eit^oA 
ottty «nd {he coititiaued tdcio^ die poti^- 
d^^i d quartet^ A pa{>4r only tt » tiffie« 
for two days tiSttt, a .d«^ «ach ifay. - 

The apothecary ^pprAcnding the &* 
vcr was quite fubdued, by At «rupdcftir 
dying away, flie omitted ihe powders tm, 
Friday the 5th day, and cm Satarday the 
fever returned with tnore vidtente. She 
then took half n paper «tiore ; /oHowing 
the dircdtions all along, by dritikhig plen^ 
tifully of dil tftiftg iiqtfers, as barfcy wa- 

tei>.^C« :/, • M.:- ■ • :i'.; ." ir: V t 

», • • •. *'/.. ■■■V ".-. '. /:-■ - ■*'" r'*7T •\."'-- ' 

. . f '' • , .1 . ■ ,<..■•■ - rtfe 


, . *fy\ ■ ^.- • ►. ,■■'*.••*■>>•■* . 3 . '•■ ' , .> 

7 vlrttiSL' fweated^ as hefore5;aiid the.evar 
diation iailedi twenty-four honts^ * Upon 
|!u&^iiratar :feparated kindly >, and there 
luting, z blear intermifllon> ^ the . bafik was 
given ; and the fever came no more. 
And the inflammation of the finger went 

intjlr^ly off, for five weeks. 

t ■, ,. • , ■ • ■ •■» 

•' (Jurie d2) return'dj, and 
about a wetek before , its return the fpit- 
ting camie again^^ with occafionalrfick fits, 
and vomiting. The apothecary has ta- 
ken away five or- fix ounces of blood ; 
a few days after gave a gentle purge ; 
which after an interval of fix days, is this 
day renewed. But the inflammation of 
the finger ftill continues with itching and 
ibooting pains ; and there are fmall blad- 
ders of water upon the joint and extre-* 
mity of the finger, which difcharge a 
little. It is to be noted, that all thro' 
this illnefs, fhe has had* unuiuaJ pains 
and diforders in her head, quite diiferent 
from common headachs, with which ihe 
• * ' has 

CANINE? RfA^N'Ed-S. if 

- » • 

has been much afflitftcd. She has it 
weekly conftitution, bad nerves ; and the 
evacuations of the powders, tho* it te^ 
moved the fever, were fblloveed byhyli 
terical fymptoms. ^ 

June 22, 1754. 

The lady's cafe, who bit this gentle- 
woman^ was a remitting fever, which 
became continual ; and there wiis not the 
leaft reafon to apprehend fhe had ever re- 
ceived • an injury from any mad animal. 
I was cohfulted by letter j but my direc- 
tions came too late, for I think fhe died 
either before my letter arrived, or very 

foon after. 

• • • ■• 

Boer HA AVE has very diligently col- 
ledled from all preceding authors upon 
this fubjcdl, the fymptoms of madnefs in 
a dog. This is a tafk of great confe- 
quence, as at the fame time it teaches us 
to diftinguiih when a dog is mad, it gives 
a caution to avoid coming near him, and 


«8 .:,4/rR.^i).JI?9. QN 

e dreadfiil con&quences. But as Bo^ 
ierbaave feems to have de£bribed a; mad 
qog' not from his own bbfervations, but 
fioip. thoic of otUers^ I think there ar« 
£>me circumftances in which Ije is mif- 
ii^Lcn^ which I fhall take notice of, after 
giving his aphorifm upon this fubjed. 

^^.M f ME ' figns of an approaching mad- 
^ nc^ in dogs are, accx)rding to him, 
«*^ithefc. Thejr become dulU iblitary, and 
:^ efideavour to get out of %ht/and hide 
;^ themfdv^i they are mute; as to their 
^ Back, but make a 'kind of i^uitnuring 
^« noifc, refufiiig, at the fame time, all 
>* kinds of meat and * drink, ; t'hey * are 
^'enraged, and fly upon ftringers, but, 
" in this ftage, reniember and reipedt 
'*» their maftct^* l^heit lears arid head 
^^ hang 40wQ, iaiA they walk nodding, as 
^« if overpowQ-ed by llcep. This is the 
.«• firft ibge of the diftemper, and a bite 
^« received then is very dangerous, but 
" not of the worft kind. Then they 
: ** hcgi^ to pant, and hang out their 


C'A'lsri]<TE ■^A'dlsFEUs. i^ 

^^ tongue, to emit a great deal of froth 
** from their mouths, which they keep 
*' perpetually open : fometimes they 
** walk flowly, as if half aueep, and thca 
*' fuddenly run, but not always direftly 
*^ forward, as is pretended : at laft they 
"begin to forget their mafters. Mean 
a time thdf eyes look difpirited and dull, 
" full of tears, and red ; their tongufe is 
** of a lead colour ; Aey are fuddenly ex^ 
•* tenuated, and now rage cxceffively^ 
« They fddom furvive this fecond ftage 
" thirty hours, and a bite received at 
" this time {Boerhaavt Ays) fe incurt* 
«* ble 5 but the mfore raging the animal 
<* is, the longer he has been afieded, and 
/* the nearer he is to death, the moie 
" dangerous is the bite^ the more violent; 
" are the fubfequent fymptoms, and the- 
^\ iboneT: ^hey come on ; and wee *verfa.*^^ 

In this defcription of a mad dog, our 
author iecms to have con&umied the' 
iymptoms of the dumb tnadnefs^ as it is 
calledt with tlaofe <^ the ta^g madn^i^ 


Uiei^lbrmer of which I took notice. of 
bi^fpre ^ and ib far is a dog from being 
liidt^ in Jthe raging madnefs, that he will 
b^k^ inceflantly ibr a whole day or two^ 
ifi^cionfined ; and one of the firft and 
thoGt certain iigns of approaching mad^ 
n6fk)in a. dc^ is» a remarkable alteration 
iHnthe tone of Jbi8 bark» which jfounds 
hoarfb and hollow^ and which, in no de<! 
gree refembles murniuring. This I have 
had frequent occafions of obferving, I 
anL.&n£ble> however^ that .every dog that 
h haaiie. does ^ not go mad. Boerkaave 
I)as Lfdfq omitted the moft certain cbarac-i 
ter^ftic of wmaxlnefs in a dog» 4hoM find 
his^JCOtnmentatorK KanSwieten^ has quo-^ 
ted it fjropi , my pamphlet in 1741. It is^ 
that i all other dogs» tipon fmelHng the 
dog:' going >n;iad^ will avoid him^ and run 
away >yith horror^, fhaking their heada 
with fome vehemence. Lommius fays, . 
other dogs are^Ven terrified at the fight 
of vimad dogs^ or at hiearing them bark. 
I have^ iteqi^titly fe^ei^ a very finall mad 
d<)gitwalki0g,^ X)f;jrath€tr trdtting^ . down a 


CANINE M'A^D^E9rS. jf 

ftreet, and obfcrvcd very large andfieroi? 
dogs come out of houfes, and the f^t^i 
of inns, as is ufual upon aiiy unc(^mciti' 
noife, with an apfyarent intcntibn* of wo^' 
rying the little miferable aniaul$«i but 
the inflant they approached, they .turned 
away from him with the utmoft preci*^ 
pitation, and made their efcape with 
all imaginable figns of terror and con^! 
fternation. ■' -■ , 

/./ ' 


Desault relates the cafe of a ladyv- 
who going in her chariot from Btmrdmu^ ; 
to Medoif obferved a little ftray dog upon 
the road, which fell upon all the ihepn?: 
herd's dogs, and the dogs at every. hou&L- 
(he paiTed by, though much larger than 
himfelf, and put then) to flight. . This 
behaviour gained the lady's efteemib far#t 
that ^e took him home, and by thatx 
means fhe, her coachman^ and fome o^ 
hei^ children were bit. Hence I ihouldo 
depend much on the experiment .menn > 
tioned in the Hijiory ofthe^ Royal Academy ' 
ofSciemes. This is^ when a dc^ is skilled 



upon fufpicion of being mad, without tH 
abfolute certainty, to rub a piece of 
dreffed meat on the teeth and gums of 
the dead dog, and when this is o&'ered to 
mother dog, if the dog which was killed 
Was mad, the other will refufe it with 
great terror, or otherwife he will eat it. 

The following cafe will furnifli a moft 
remarkable inftance of the diftingui/hing 
faculty of dogs upon fuch occafions. 

Is January y 1747. Thomas Field, & 
Bafltet-maker and Turner, who at that 
time lived next door but one to Haddock's 
bagnio. Charing Crofs^ but fince kept a 
Turner's fhop in King-Jlreef, Wejlminfier, 
was feverely bit about the middle of the 
arm, by his own dog, a very large ma- 
ftiff, that was mad. There were two ■" 
very large wounds. A tumor enfucrf • 
more than twice as large as a tennis- 
ball, and was propagated as far as the 
IhoviHcr, looking very black, and bein^ '•'^ 
Mccffirely hard. Another dog belonging-"'^ 
-c- t- ^ to 

CTAiK 1 NIB MM D I* E S ft 33 : 

to jtbe- ' aext hoble^ - was ^it by tho - lamtf 
doj|ty much abcKSt the fame time. Mr.' 
JFVai/ immediateljr^ confuted Dr. Mead; 
by whofe ^redHoh he was falopddl, took 
the Puhis antifjifiu, of the ' aih-^oloured 
Kverwort and pepper, and an ointment 
was applied to tfa^ arm* The neighbour's 
dog was prudently chained up, to fee 
whether he went mad or not, but Mn 
Field's dog was killed. Some antidote^^ 
was alfo given to the dog that was pr6« 
ierved. Mr. FieU continued very well, 
except that his arm was painful for about 
a fortnight : but at that time the neigh*^ 
hour's dog going raad^ he was ioiipru* 
dently hanged upon the iron rails which 
fence the ft^ue at Charing. Crofs^ juft 
before Mr. JP/>Zs^& door, and in his %ht. 
This put him into the utmoft confteroa* 
tion, and terrified him almoft to a degree 
of ^adnefs. 

Ax this time I was applied to» I di-* 
itGtcA a ix^erculrial ointment to be rubbed 
into the arm, rad: £000 rafter this ^applt^ 

D cation^ 

34 . A! TKBA/ri«Ei ON * 

catioojr «thfi: tumor V fubfi4^f and the 
wounds difcharged a well-digefted iiMtf> 

ten 1 think he alfo took fmall dofes of 

, • . . . ^. 

^urpeth, Mmeralp.hut xaxmot be ceartaioi 
At. this ?nd>., howevsr, q£ ^ month frovp^ 
the bite, >yhen the wounds healed* her 
came to my houfe alone, naore raying ' 
^ifid ^elipjQus^ than I ever faw any onc^ 
m:u^r>t]^eu}flaexipe qf ^£,madn^$.,ft j[ 
iaiinqdiateiy. pf dere^i t;vro Xei;vants to yoft* 

^Md itim hcs9ie,, and g^Me him> as fp9» 
^a it could be prep9^ed| a bolus, widb t^ 

fif^ps of fMP^ti> }4mif(al'. . 1 He '^jg\<Si^ 
ately wa« put to bc(jl> land ii> one • ^^MMor 
^fter xht TCurpeth Mineral^ he tojok .thfl 
Tongtm^ repiedy, as it is called, confift-** 
ing*of:nat.iyea&d £ii^titip«s cinnabar, eacht 
twsntyrftvje g?ainsj,mth. fourteen graids 
oi itn\di$i*. .Vho^ Ti^peth Mwerali thoughft 
il^ng. ei»etic# and in a very lai^e doidg 
neither vomited nor purged him 5 *bw; 
he fell afleep in lefs than half an hour 
•aftpr; taking. xh^.,SQfiqmn remedy^ and 
contiQued-fQ nioie,.bours,^ fweating. qottfib^ 
dtt'ably,;allwthe timeiK In the morning 
v*j - * i . he 

C A If I Wm • M ADJ5IE &S. 35 

'^fl^ r ttiC^A ^iVifdh * HeiJ ri:.Jjiow alive, 
tnd'haiS never. liad:> >tfae Icaiffi 'telapfe% I 
^c^LiH have taJoeik Dotice, thkt hie Trent 
tfbi Grmjefend'^ and^was^ dip'd iAi.tSaic fak 

^{^^Bff T hi$' difi>#der was ^tfetided" with 
t)li(bi*Veiy'fttriaffetbfe circuinftahte, tda^ 
we to whicit' r#ioft be very* particular, 
i^k Maf conti^beite to ^ftat^^ jst potnrt 
€9r^ gl-dat <S(^tlf^li€nce, tb- -any who 
fi4t«ttft» mayi^be-' in doulrtj whether 
«kher man 01^ dog> labours (under this 
diftemp«r. • 

. .' ♦ ■ . - ■ ■ « • 

< > Fmli>, amoBgft other things*, ddalt in. 
liuiiteF/ aoiii had feribmeyeafi^'tuf niched 
m^ femily ' with: it. This bi-ought h\m 
^ice or. thrice a week toiQiy hou^j 
;|ftd. bdSdcs ^lis^cfaeihad a^very >p»tic}iik!^ 
iiitkiiacy 'Witb/iionc^ of my. dortieftle^j; 
illionif I bdievbthd feldom* &il^ viiklA^ 
tefotievday. Tisis mintMe drcOttU^lE^^ 
^.^QQ^mcirttQnii lD:^i9bew^faow:iiteb«fiBRUi 
bi\:: Da very 


very familiar with tlirec fpaniels I then 
kept. Thefe creatures were lb remarka- 
bly fond of him, that whenever he came 
to my houfe, they leap'd upon his lap, 
and made him all manner of careffes. 
But the night he came under the influ- 
ence of the diftemper, the moment he 
entered tjie kitchen, they all ran away 
to the very top of the garret flairs, bark- 
ing, and making i kind of howl, and 
with all other figns of the utmoft diftrefs 
and confternation. And this they re- 
peated every time he came to my houfe 
for three years after, and were at laft 
with difficulty reconciled to him. , 

^,: It has feemed pretty extraordinary to 
^IJlofi authors, who have treated of thiS 
4iilemper, that the poifon (hould conti- 
nue fo long, as it were dormant, with- 
out producing any diftemper ; and at laft, 
without any manifeft incitement, pro- 
duce a difeafe, of all others the moft 
alarming. And this not at anyfbtcd 
period, but Ibmetimes in a very few days. 


<U)d; in other inftances, after ^rtJriteml; 
of tnarty months, or even yearfe,' irom ic^ 
cciving the contaigion. Bat I' think i!^6 
wpnder will ceafe, if we confidcr that sdl 
difeafes propagated by efftuyia, cpntad^ 
or inoculation, (not including the wounds 
of venomous animals, as vipers^ andma^ 
ny others) require fome tittie' befoi-fe 
they ^ can exert their efficacy, in fudh 
9, manner as to produce a mfariifell di«- 


Thus neither the .fmall pox, nor con- 
tagious fevers, produce the di^^emper im- 
mediately, or after certain and itated in- 
tervals, but in fome conftitutions fopner, 
in others later. This was manifeft in the 
(Celebrated infeftious diftemper which was 
cjoptrafted by fo great a number of people 
at the d/J Bailey 9 in jiprih ^7S<^ y ^r 
fome were feized in a few days, and 
others after fix weeks. 

I* ■ 

The. itch does riot appear $5 loon as 
tn6 ihfeftion ii reCiSlvea,' nor does the 

D 3 leprofyi 

lepfofy 5' and neither at any ftated perykt^ 
And tf i tftifty give ct^dit to the Wibft) 
fblemh alTevefations tf many patianflfr;> 
^ilrha ha^re^^n fotoewhat «nfortana?lc iif 
tliefr 'ittiottrt> Cottle: (have percciJ^^ed ■ ^ 
confequenccs in twenty ^biur powrs^ ©oitt' 
the receipt (rf^the inftkaion, whilft dtfitei^ 
havie, 'for^fen* yAai*, ^teWained in a^-* 
fMearancfe Cotatfy frefelr^m the diAenipbf; 
till af laft 'it has- difcovered itfelf with t 
degree of inveteracy that might hav4 
been expected from its being harboured 
fo long in ^he habit. 

All tfedfe varieties, lip wever, as wdl 
as thofe which occur in the diftempcf 
that is the fubjedt of this treatife, A>ay 
readily be accounted for from every cifr- 
cumftance ' that can <:ontribute t6' i 
ciiarige either in the vital fluids, or tfei 
folid fibres. Thus every evident qualfty' 
of the alnioiph6re> as its weight, con- 
tents, and heat, befides perhaps itmnjr 
other properties thereof, with which we 
are unacquainted .; fbe faiiibrity of food, 
and the regularityr' 6r thb i<6Verfe, With 

■■^ refpedt 


rdped: to the ufe of it ; exercife> the 
paffions^ the excretions^ ileep> fingulari«- 
ties in the conftitution, and the degree 
of infe<Stion received, either with refpeft 
to quantity or malignity, may accelerate 
or retard the progrefs of contagion re- 
ceived by any means whatever i or may 
even totally diflipatc it, fo that it fliaH 
never a<ft in fuch a manner as to produce 
a diftemper. For contagion, like treafon^ 
feldom manifefls itfelf by an overt adt^ 
till it has fecretly form'd a party in iht 
microcofm, fufficient to excite a diftur-^ 

What I have faid is true of every 
diftemper I am acquainted with, that is 
propagated by infection ; and that it is 
true in regard to the Hydropbohkj is 
proved by a great number of cafes re- 
corded in the annals of phyfic, which 
evince not only, that the poifon of a 
mad animal exerts itfelf at different pe« 
riods, but that fometimes it excites a 
kind of pqriodical madnefs^ which jrpcurs 

D 4 afto* 

.:; ncifter. t cesttin . intervalk ; .. and. . thsatiJitzany 
v.: people have been wounded; by mad ani* 
HW^Si vdi0 never. contraacd .any diftcm- 
i||cr:&owi :it,: jtbtf ijothing had Jbficn at- 
7^e9ipl^.t9 pVe«ent it,; ; _r 

- 1 •-• 



«■ ■ t 

J oH<^£ I^nfw ^ footmany belonging to 

a;iyciy nca? relation of minc^ uwJio was 

. ibrce Sina^s bit by dogs roanifeftly mad, 

jii.9lPQ}t|ch.thatr^ver^l animals bit by the 

jfen[ie dog€> ; n^ar the fame hour, coptnwJt- 

edt the diflemper, and died^ This fellow 

i^. ^\yas iib pbflinate, .that Jje could not? be 

., perfuaded to do the leaft thing by way 

of precaution, and yet never had the 

leaft tendency to an Hydrophobia \ fo far 

^. <jfrom it, ^^t he dipd mjiny years ifter, in 

n : , ■, cpnfequenoB of drinking . too much , at an 

i /lijk^^^Qi^XKW of which he 

J .wast, mafter* . r 

;:l'. • 

\ ,, As to the ti«i9 thaf tliQ infe<aioa; ^re* 

..^ cf^rqd ,by^ th^tbitp of a mad animal may 

continue latent, without producing ja'di- 

ftemper^ Caelius Aurelianus only obferves, 

•:H that 

that fbme fall ill fboner after the bite* 
others later; that fome are a year, or 
more before they are fenfible of itB ^ ef« 
feds, but moft perceive it after forty 
days. Galen is of much the fame opi<- 
nion. Diofcorides relates, not upon his 
own knowledge, but report, that people 
have gone mad feven years after the in* 
fedion was received. Paidus and ASu^ 
arms agree with Galen and Diofcoridef^ as 
to the time. Stalpart Vander Wieli\w>t^ 
cafes from feveral authors, where the in- 
fection has broke out in an Hydropbobia 
eighteen, thirty, even forty years after 
the bite. 

Of the three cafes Wldanus gives us, 
the two firfl: continued perfeftly well for 
three months ; but^ the man who received 
a fcratch upon the thumb, continued 
well about feven. In Dr. Lijlers patient 
the confequenccs of the poffoni ajipeared 
in five weeks j and in Dr; Jl^iri^t in 


■..*. J 

4* A' TJl<E Air I SW OH- 


♦ ^«'.-i«.i .^r;# .'tr«. .. I. r.^.l* -j; ... .4. / 

.BiTT^tberc arcanfl:aacc$ of perfons af» 
i!b£l;edivvk)h tlio difte^ in twenty-rfbur 
]|t[itts, 'lof whacht .iiowfiyer, I : have oevjo: 
ifti^ an example talii very latd;/. But I 
Iji^lfl T^mark^ tixat L do not abfolutely 
gbfe ci^edit .to tkoib hiftories of cafes, 
which riq)rcfent the contagion as, lying 
dormant for a great Jiumber of. years, 
i^d at iail producing: an Hydrophoina^ 
Thoif who relate, them might probably 
^ make >*a- 'Very obvious miilake.; It has 
b^%femv^ above,. that the. HydrQ^ 
fhobia is frequently obferved in many di- 
ftempers befides that excited by the bite 
of a mad animal. Now perhaps there is 
fcarcdy a perfon to be found, who has 
tiqt at one time or other been bit' by a 
dog, 4^ had fuch intercourie with that 
apknal, as i% generally thought ; fuiEcient 
tl^ proqjiLice an HyJr&phobia. If therefope 
turenty.or thirty* years after, a perfoii* 
fcovld Jiave any other diftemper, attend* 
ed with an averfion to drink, it is' very, 
likely, that either the patient, or his 

> 1 friends. 

C A N 1 NE • MA D N-E 8 S. ^ 


friends, may recolleft fomc kind of com- 
munication with a dog ; and the HySto-^ 
fbobia^ the* from a irery tliffcrent caufe; 
may be unjuftly afcribed to the innocent 
animal. ' I^bWcver I think it isr agreca; 
that the diftcmper moft ^ncraHy heghii 
to manifeft itfelf about 'forty days aftet 

the bite. '^ 


' That the diftemper excited by thfe 
contagion of a mad animal is fometrmeJ 
J>eriodical, and not always immediately 
fatal, 4he' following hiftories will ahuh* 
dantly evince. 

Rose I us, in a letter to Hildanuu 
which the laft mentioned author has 
given us after Obfervat. 86. Cent. i. m«- 
forms us, that in the month of Augt^^ 
1581, a lady received a wound in her 
left arm, by a mad dog, which -(he l;lad 
the misfortune to meet in the ftretft! ' A 
ftrong ligature was made upon ^fieP^tftm' 
above the bite, and topics applnidv^^lf'^ 
place was jilfo tauterifcd^'^and^^ 

'.i i 


44 SA'^TtJ&g^^FS^i 6^-' 

fitbi^ caode upon it. 'J^dKlphiirmci vmk 
l^ttfcribed? by hbr i^fite After* this 

fltd^ciofitiriudd weH; till: the^ feveftth ^ar^ 
iife>l*ih Hie was fciied tirJith vidcpt pains 
III ^ the arrai fornicrly wotmded, wliich 
fei3fft6d to her as ftf ^a . dog wis - gnawing 
ife'^ 'This was flrcccedtd by *a taving, and 
fiiffirfcftii; a ' tndaricholy , and dej edetincis ^ 
pirtinaciotrs watchings, infatiable thirft, 
a fever and great wcaknefs. She had a 
great averfion to food:, but had no JE^f^ 
. ^ophihiat * for fhc drank freely. 'With 
jSroptreare, in a few days, (he recbvdredi 
^e fymptoms gradually difappearing^ 
^even years after thife (he was again feized 
^ith violent diforders^ which began in 
' th'i fkme arm. The place patticulatly 
?J*feiere the bite formerljr" had beieri, wis 
ijJJftfcmdy painful, and fomewHat coin* 
Viifffed. ; Befidcs this^ fhc felt almoft in- 
^&iFeraWc gripirigs, and, at the fofiie timei 
•iier bid witchings and thitfV retunied; 
^owcvt*, flic, it leaft, feemed tb be 
'etircd a fecond time f but in £bt years af- 
tfer an theiamc* fymptoms returned. 
I > - ' This 

6a nine MAfD If E j^ S. 45 

. • . - ■ ■ 

THis was twenty years after receivkig thfr 
wound. The next year fhc had anothcar 
fit of the fame illnefs jj in the twenty^ 
fecond, two ; and in the twenty-third# 
three ; and in the year 1604, when thig 
letter was wrote, fhe had been tormeBted 
with two more. It is likewife remarka^ 
ble, that £he felt convulfive motions 9!q4 
pains in the wounded armi uppo .any alf 
terations- in the weather* .:: .^ 

■; .; '\ 

Dr. List£R tells us of a tradefinan in 
Landon, who had, for twenty-five year^ 
been troubled with convulfions of ' ' 

headf which 'often obUged him to • move 
it with great velocity, fideways^ froca 
fhoulder to flioulder ; ^nd in thefe parpXr 
yibis^ fvhich feized hint in the 4ii^iM^* 
he would niake a ftntnge npife, toksp^ 
bling the barking of a;dpg^ Upon xssfp^ 
minatioh the Doctor thought tJiQr? 19^ 
great reafbn to believe^ that thi^ 0^4 4j^ 
order was originally caofedjby thCrWtici^ijf' 
a dog, which; he had received nianvtjreatf 
before. A And in. this he was.ttqd^ cm^' 

j|fiQfidd» % ibixie' accounte >giv^g <lum bf 

r^Jbi th/e. Fhiloffkbhical TranfaSiom we are 
ioIdLoti^ ia irriiW, ibout the LsiAof 0k:** 
<fi^W* 1679, t,w<?,|3^^ aboiit5fiv^or te» 
mvsu ^4r • handed. iU)4 wafhed th/e ' headi 
Q(^>,rfdog^ whkh .ha^ bitten by a 

Umad one. The^4ag: never, //^asr. ^iibir* 
dered, but, about May^ 1680, the chil- 
4l^^ . rWa!a ieizcd c,^^^ ^ ' giundtng pain 
tQwards ^^ bottoms of their bdlie^ 
"vificfy, afcended^. gcadoall^ tow^rdf theiir 
jftiy^. Ahaatjfuiy^, they -w^ere fed2ie4 
^ithta flow; Ru^, ^aiiui fakting fits^ r wheq 
tkA-.paia. a0aulM them. 3<x9e ^Iff^^afU 
t^^ this, paj^ gpt above the %maci^, 
^jWAwhidb th^y^.bad vecy viofepfrjCon^ 
YuUivQ^; mqtiorui,, .partlcukiiy abovt the 
ig:|0^ad:i and 'b^yji with fpam^g at thi; 
aM:^!^. uir the, rjntervak of - ^if ^ita^ 
7^(^ fyfnptQnas:iA;oQt;iitued ap^lf^r^M 
^Uth^J^tfr^^epdof -r%^iij.t^^ $}iex 
V^ taken with, a ^^ afrW^er,- i^ iq 

r^^ much 


much that^ upon the fight of any.. thing 
liquid^ they would fall . down as deadt 
and continue ibmc little time ia a fwoom 
Then they would tumble and tofs with 
violent motions, and diilortions of thick 
bodies, accompanied with heavy- groans { 
and ordinarily, the eldeft especially, iharl« 
ed and barked, and endeavoured to^ bite 

• ■ • • • • . 

like a dog. In about an hour they would 
recover, and creep away, as if afraid of 
any body that was near them. T^jf 
came entirely to tbenjfelves when the fit*' 
went off, which returned daily, till about 
the middle of September ; and then their 
difwder was more violent, and they mortt 
wild than ever, infomuch, that in tbtt 
intervals, they could aot endure aiiy com^ 
panyi riot even that of each otl^en Thin 
continued about- a week, and th^en the 
eldeft cried out to his father, as^ one iuis 
prifed, that he was well ; which acooTH 
diilgly both he and his brother were, and 
continued fo for three or ^mr^daySji m€ 
then they fell ill agaizi, ^md reooverfid M 
ieveqdays, without any furthei; «tlapfiu 
.-.^^■- It 


It is remarkable, that they both went in- 
to, and came out of, their fits at the 
iame time. It is alio worthy of obfcr- 
vation, that in Auguji they took dofes of 
Mercurius vita and antimony, with ^- 
nice treacle, and the teftaceous powders. 

I HAVE been told alfo, by Mr. Blackeft 
a gentleman of veracity, of a cafe where 
the diftemper appeared periodically in a 
boy, who was whipper-in to a pack of 
fox-hounds in the north of England. 

I WAS a itw years ago confulted for 
Mrs. Clark, a relation to Mr. Barrow^ of 
St. Jobti's Square. She had been for 
upwai-ds of two years affliifted with a 
fever on her fpirits and nerves, as it was 
called, which reduced her (o very low, 
that ihe was unable to fee any company, 
and was ready to fmk at the leaft noifc. 
Every objefl feemed diftorted and fright- 
ful, and fo great watchfulnefs attended 
the diforder, that fhe has been often fix 
or eight nights fuccefiively without fle^, 


thmigh one hurfdrfecl arid' twetrt^ dropV oX 
Liquid Latidamm were gi^e/f her at ii 
time- to torocure it. Her Mefids tried alf 
mekns -for her relief that' wdffe ' kdviifdcr/ 
biif V^^ithout effca,-and flic 'v^as fuppolecJ 
J>aft alt hbpets^ of recovery*: ^-^ '^' •■''--■'-■ 

Sh*: took a ftw dofes of thb 'Fever 
P^T£;^(fri tipoh a fupjxi^fition/ that her* dil^ 
ord^ proceeded from a flow fevers' ^^i 
in a few d^ys was perfeftly well. Ai 
this time I had not feen her, but fome 


little time after, I became acquainted 
with her, and learned from herfelf and 
friends the following particularsv ' ■ ' 

J t 

. wT* 

^ Shi: had been bit by a mad ^6g abotit 
two years before, and had nevei* feceif 
perfeAly well afterwards. But the next 
yean nearly- at the fame feafon ''in wHich 
flie hdd recd«^elt the- wound;' TtU' tKte 
fymptams'abwemehtidned apptarcd withr 
^eat violence-. -What meafuresf'were* ta- 
)ktn I canHbf TeSffi, • birt "in Tome"-^ 
flic bddamc^ ttuch -TietW/ ^THS^ ieconff 
' ; :'- E year 

19 -'.43:T^fl^j^A»r I^iKi "On v 

imfM %T^o s<^^im.^ Mitdm 

^«f9 ?^^ (W?fifpcr^«c4rfm Wore J ^ 

it , >!ir^ tt(?fv ,^Q took ^e. ^Vw^ fi9m^ 

Yi^ the juc^cis: wentiOflcd !|bQV4» : i Mrt 

femtibn is, that- ujpon j tHo^ - P^!9<%|| 
returns of the diforder, all obje^ a,p-» 
p(;air^ Xd) her red^ and ■ fkpra^ on; £u^ 
Thh Ifdyiff, I, hear, at thi?. IWJC.^W^ 
j^ in,^ goQ4;ftate of ;JiesiU|h, <»»d Jt 4^ 
13|?t hjwr ihe J^asi ever Jiad apy return, .-. 

X^Xn^ cafe of ^^a^ iV^^ii?,, record ia UmS 

J^kiloJkphki{l ftrmf(t^hmy No. 495. b a 

confirmatj^ pf w^t is i^t prefeat adr 
yanced, at the fame time that it proves 
i^'LtQhm aimnm terr^m not to .be 


,, 'J;ij4$ maisj was, bit byi jt'mtd dof/OB 
jtJie tfew»bv*l>9, ^-fi*^*?^ before Michaeh' 
ffias diy, 174,1. The w<»if)4 ¥m9 ii}«et>7i 
fied). he was blooded ; he uied the eold 
bath> and took the Licbm cinerem terrefirh. 
wi^ peppc;r, as^ dkeded in ^ Difpon- 


faty, under the title of Pulvh AntilyJJuil 
Bot at the fult nifoon, which happened a 
fiWWiight after, all the fy mptoth'i of rnadi* 
nttfscameon with great vJolfertcc. Th^ 
jAyficians treated him very prudently M 
jthe- atftiphlogiftic method, by bleedings 
blifters, gentle opiates, and laxatives'. 
His life was preferved, but he was not 
tbtarlly cured j fbr at the period^ of the 
modn, the fyhiptoms returned in fottic 
degree, but (lightly. So f^r the Phihjh" 
phical TranfaSlions. But upon enquiry I 
«m infwmed that the man is now dibad, 
Jand that durmg his life he was always '^M 
thft foil moon feized with difofders of 
thfe head, refembllng thofe he fell updft 
the firft att^fc, attended with a flight 
alienation of mind, and an involdikafy 
difpofition to ramble, which laid hinl 
'under a ncccffity of bleetjing as ofteh as 
the dlfordcr returned, from which he 
found great relief. '" 

* -^ 

'E^-2i' ^ ■•■'■ ^ •■ ='■ Vt 

I r-, -• » ■' . . 


> » 

. It appears from. * Calius AurelianuSf 
that fomething of this kind had been 
obferved by^ tljie ancient phyficians, the 
truth of which, however, our author. di(^ 
putes, ^* He fays, we are not to give 
*J credit to Demetrius', when he aflerts 

.*/ that this,- diforder may be chronical j 

«*., .»•■•.*■ •• '<. .J. 

,•* for he (Demetrius) fays, that fome 
.'^ have been for tv/o years afFed:ed with 
*V a flight degree of an Hydrophobia** 

The fyraptoms of this diftemper vary 
£o much in different perfons, that it is 
Aot poflible to defcribe it with that ac- 
/p.uracy which the importance of the fub- 
jeft fliould feem to demand. And it is 
fomewhat more difficult, becaufe the 
diforder is providentially fo rare, that no 
phyfician. has feen a number of cafes 


• Nee Dcmetrio danda fides eft dicenti, quod cti- 
am tarda hasc pafBo poffit efie, hoc eft diuturna, quam 
"Gxdtci Chroniam vocant : fiquidem dicit in ifta paf- 
fionc levi timore affcdios biennium tranfgifle. 

Calius Junlianusy L. 3. Acut. C, 11. 

C A N I NIE A M- A:D N:E S'S. 53 

foSif i^t fof fo ample an information aff 
is requifite for drawing an exa6l . pid:ure 
of the difeafe. And the iyftematic wri- 
ters . have in • *gtnefal coIlc6te<J' all ' tlie 
fymjytoms from 'all the cafesi-uponrecorcfi^^ 
and' united themiin Yuch i. manner, that 
a perfoh who Tftcttte their accounts, Vi^ould 
be^'inclined to think, that every.'fymptpm 
whiah has ever-aj^eared iaoiie patienty 
has i been obferved in all. But-: this is 
n^Trtie, either >with refped: ,to;. :brutes"bb 
ipcn, ^ It is in this^ manner -that Boer-* 
ipafOe,-'Tis I obferved before, his rdt&ribed 
the Hydrophobia y \yyxt I think his com^ 
mentator Van Swietert, has fet it in & 

juibef light. ,.;'.•.: 

* - • • 

■ * ■■:..'■? 

/:BuT of ' all the- authors who have 
treated this fubjed:, nonerhas done it. with 
greater preciiion, or prefcrvcd the refcm-? 
blance of what actually happens in an 
Hydtophobiaj tnore than Ca&'tis idure/ia-^- 
Hus^ a" moft excellent authory^'wfeh .«- 
fpet^:- to- every thing but ftile,' Vehich^is 

. E- 3 .. beyond 

bc3^nd aH tncafurc biaurbarous and jWJf^ 

' He telb trsi L. 3. ۥ 14. that tbep^rtt 
faff^^ fi^fii ^^cb origpmify received (iH 
W)imd* And L. 3. C;- 1 1? he fay3> dfeat 
thofc who arc juft abcnit to fell intoaii 
HydrapBabiaf zct icizcA with' a cerCadi 
anxiety^ without any^ wid^nt rcafonx W> 
prone to ahga*, have their bodies': f en-; 
dered tmca^, : and fubje^ted to prctcrWH 
ttiraf and Uirafual moticttia^. • Their flsdji 
fe either rcftleft and diftarbed, - or - they 
are ^flfeAed with perpetual watching*. 
Their alft^ms iDecome corrupted, their 
ftbmachs opprefled, and they are irididbd 
to ftretch out th^ir legs and arms. They 
are afflfd^ed with a ctaitiriiial ofcitatibn, 
ahd a violent naufea, or tncliriation to 
vomit; They make unaccountable com- 
plaints, with refpefl: to the weather,' as 
thick and rainy, when -at the fame time 
the ftate 'of the air is pure, ferenei and 
clear. They are rchdered uneafy, fittfulji 
and difcontented, by lowers arid falls of 


C A-NI N E - JK A D^N^ s;5. 5$ 

rail), and ha?e an unu&ial fh)a& appetltA 
for drink. 



-. W-H«» the-difowki" cdti«s foi»,-0tey 
«% afflkited with a vk>l«Rt oii^ in&tiii^ 
bk thir^> but, at the AtA^- time, tut# 
ilrock with ati unadccuhtabtd terror atiid 
dre&d^ not only at the fight, bat ^jfo. ^t 
the Ibind 6r -nftaii^ of waters Thed tfae|r 
become afraid <^ fomentations of ofl xx&A 
for their relief, and their pulfe is thick, 
ffiSall, «nd irregular, Sonie are ietzed 


M4A a Hight fever, convulfiv* throrws tf 

the ftomach, a tofpor and iiumbnefs tX 

the joints, a pretematurid cleyation <tf 

•the Praecordia to the iiiperior parts, anft 

^ coftive ftate of the belly. * Then ithfijr 

difcliafge their urine ff cqdendy, and 'by 

little at a time, and are fdzed with a 

trembling and convulfions. Their voice 

becomes hollow, and refembling. the 

barking of a dog. Thepoftiire of thefr 

Ixxlies is like that of a dog;, when, lying 

afleep on the ground, Their rclpiratioh 

is difficult, and their whole body is ren- 

E 4 dcred 

^ered higWyiirfeftlefsyjqind-uneafy, \}pim 
the; entrance of any perfon into theiioomi 
for fear he fhould bring water with him. 
, !!Jph3^r^^^£W.4)i:oiiftteftwcefbccoOTe^^^^ 
ifeir- bo^kf jfl?n4^> aildv the fupciiof 
|«j;tj:.€rfiit^ii^ %A^ f&v^si with fw^t; 
g?.he tppgji% b^ngs ftu t,Q^; the nlpu th, andi 
jg. ,g!|P4,j^e^|Jfi£4s ;isif§i^^ 

^ai«l;ary(,qfl^ fluids .; 

• • • • •. r • t . ' ■ • ^ .-. 'V 

ISplflOf; .•',%q&ift5?;ife.u«l| viiitli, an, ntiofir 

#» SM i^R*^^lfl\f ^^""^ the^s with liqrr 

Jfmkh^ aeknowledgf;j,th{it. it i* a natursd 
Jifluor, and ,.tp, which they. have been ac- 
. cuftpined ; -bat when tlojey fe^ il; rPUt ia 
motion, reced?. from it. with die utn\Qft 
'iverhon. . :» . . • vL- 

(« . a. . .y 


Thus Soranus informs us, •tha4*''he 
knew a perfon labouring under this dif» 
orderC^'Viiib imads' :fvi^h^' i -ebn^f^dif p %ut 
telk. tis,--at the:- ^]^ iiim,^ tb^%& ¥<^Iti 
not pcevait t]fp9& Mrn^fo ^^ke tW^#y'' 

% . . I 1 I ■, . ' • t 1 - • , 

h - ' * 

•''i' A«T<8f«:i<*JS-alfo g?*^'^"^s aii4niftSH^ of 
kf^m ^ho laBdiiWhg'tiriaeF ^=dlf^ 
order,- tuflbfaidcd .hirtifrelf • witH' his 'irfeTJi^i 
p]?cfi\tk- iiread of water, * the 'darliiigf ' ffi 
quor l»^*(^hieh lie had *cch fcr raicfi'^l 
'cAftoififc^ 5 TSnce, ki^^he^ hotf eft' %ittKfe 
:he iiad 'ri«Veir ifelr the fihalleft cmotSbni^'dF 

1 ^^EtrtffiMWs,- a fdllblv^r of ^Bem/Sffi 
:mik«fe fti^i'ntioh of a c^itaftt phyficiitf^tft 
-bouringiunder- ah HydrcfMiay^\iq, 'e'^jfi 
fcious of -the > ^danger,' carrteftly int^ektiJl 
thofe who ciitfttcd the rddm to fcccp'^^'^ 
Ja diUmc^fkOA him; and at laft, z'icit^ 
rfent of tears barfting from his eyes, 'ttlc 
drops had fuch a furprifing influence upon 
i him. 

1^ e A I'P RE. A/r IBH ] N 7 

lum, that he ftarted up> and tore his 

ty,jRoMiA,mfk\mf9ir'^MSf ihtt be 
i{i£lf^tiiUHii^d Mrith i;bi$ difordor, ilrock 
SfiilfkMfm at) i^ ( nafttbec-a l)fCRft«. ; it 

^kipGifftioiv ; is jft^c^Bt to ^9 ^ go&^a) 
|4«»r!9|j'th«5 fyi^ptooM, with .pfifp?^. rJ^ 
jiar|iiqfejih»iwieycr, I, ihall be iwpre. pftr^ 
$jp}iaif^owheyQ J.^«iidea;four tD>aqeow>t for 
^tb9(Q(^ii^ ,4^ a^ueLi Mem tm^s :ky 

^i^ ^iUuftc^tiOB> J ,ih|4l fQ}fl^fp ft;; C%^ 

.cooamunicated ..^ |ne by the l4t« IV';* 
li^^htns jjf Davcntry in NortbamptonJJMre, 
f«i.|ib^^an well.Jl«i^n fo^ :^fi ^tedHve 
|)j|^<^kk«^/C«untr!iry ^nd<:w.hoie 2iq& 
jj(j^}4 h#ve ; !((;► *h^f day bten ; asorc re* 

-lypflhiily (.fuj^pUe^ .his plf^ei ; i , gentki- 
js^i, of;;^r^ff 4)^lki€S ^R4;iatcgrity i the highcft opinion,. 

Hi The 

Ct^HlNB Mi^^ITBaS. j^ 

\ Thjs perfbn wlia is the fubjcS 
Jhiftory,. I was well acquainted with 
when I w%is too young to donfider it with 
a view to medicine^ * : But two rtlic^ittk^ 
ftances cromb-tbuted to- fix his mii6d^4tlttft 
in my memory^ and which induced Qio 
mtpiy years after to be uniifhJQy liiijfiifi-- 
tive about it. ^ One wias, thftC i3|6 ^ 
remarkable for va^ bodily ftren^hi^ 
agility, «id fo much celtbritc)!-- for 
wreftiing, a diverfion much in Vbgtti^ili 
that country, that wfcei^ver any pflimmhk 
to be contended for iii the adhletic W^f^ 

hp wfts for many years eiiceptedr*^'*. 
champion not fit to enter tht^ UftsviJ^Jog 
by far ftiperior to dl others; TM^ <«»^M, 
naturally make a ftmng impi^oli £^^^ 
mind of a boy, highly and mtich afife^ted 
by the honour this unfbrttfnMd'niaii'hal 
acquired by this iupcriority, arid which 
was little lefa than that of a viCtbr i;l thfe 
Olympic games. ' i ' "'^ 


r ' •* • $ . t ■* f t r Jt ' t 

6q a treatise on 

• » •• 

'- The otKer circumftahce was ;the un- 
commdnriefs of his^ cataftrophe-; and the 
confternatioh arid terror it excited ii^ the 

• - • ■ 

neighbourhood ; thefe-madef fee "deter-* 
miiie*'^ tBe fame' foment I chofe 'phyfic 
for myprofeffion, to try hy all-jioflible 
nieans to difcover '~a- remedy forthc tJi-' 
ftei'hper of which he' dtcd ; -and- tf V have 
fuQCeteded; the. world -is oblig^ed to this 
i6an's"Misf&rtime •foi'-the benefit; ' *. ' ' 

W^Ba^ Wand,W^uckby \n tSfe'countv 
tiNortfyamptony a farmer, fomething Jefs, 
ais f remember, than forty years 'of age, 
came' \b' Dr. Adams at Daventri on the 
market day, {jVcdneJday) to confult him 
about a' forenefs in his throat, and* a dif- 
ficulty fn fwallowing. As nothing was 
thought * of lefs than the bite of a^mad 
dog, his' diforder was afcribed to a cold, 
and he was' treated accordingly. Two 
days after, the Doftor was defired .to 
make him a vilit at his own houfe. He 
found him reftlefs, uneafy, and anxious 



without any caufe ; but yet went about 
his bufinefs a^ ufual ; was perfeftly in 
his fenJfes ; free from fever ; but the dif- 
order in his throat increafcd. 

f I 

After the Do6tor had been fome little 

,«.--. - • • •. • 

time in the houfe, as he was fitting bc- 
hind the table with his patient, 
meftic brought him fome ale in. a conot-r 
mon mug. As foon as he took it in his 
hand, his patient with fome precipitatioii 
made his efcape frpm behind the table, 
and feemed pretty much convulfed, and 
in great terror. Upon being afked the 
reafon of his retreat, he faid he did not 
like to fee the drink. And then his wife 
informed the Do<a:or, that fome . litfte 
time before, he went ^o draw fome ^ee;f, 
and was fo terrified at it^ ranning, that 
» he made all manner of hafte out of the 
room with the fpigot in his hand. Upon 
this the Do(3:or aiked him if he had ever 
been bit by a dog ? to which he replied, 
never in his life. But a fervant in the 
next room hearing the queflion,.<;jij»ein 


• ^ 'A •'«•■: 

afld faid, Mafter, you may fcmttftlbcf^ 
that laft fpring (abdut four months be- 
fbrt) coming from Rugfy market, we 
met a little dog, that you endeavoured 
to catch, and complained it had bit your 
fhYiinb. Upon this he recoUefted the 
circumftance, but faid the creature only 
fcratched him, without drawing blood, 
and that he had never thought of it af- 


' "The cafe wais now too plain, and the 
Doctor made a proper prognoftic, which 
was the third day after verified by his 
death ; for from this time the anxiety, 
#^Uef8iiefs^ and urieafinefs hotirly irtcreaf- 
ra^i the paroxyfms, fuch as he fell intd 
(di'tlie fight of tht beer, attended with 
^hKftrsy' convulfions, and vift agonies, 
reflttrfnted it infervaly, and b^catfie more* 
vfelent ias death approached. The dif- 
l«xler in his thfoat increafed, till at laft 
h&died, as it were, ftrangled, and univer- 
iilly fconvulfed. Biit he fcarcely ever 16ft 
|bi$ ireAlbii, hoi- Ivas there lany a<aions re- 
^'•'' fettibling 



fembljng ihofe of a, dog ; nor barking ; 
except Tuch an alteration in his voice, as 
happens in almoft every quinfcy, that 
rlfcs to any confiderable degree of vio- 
lence, might by a warm imagination be 
cileemed fuch. Nor was his fever evei 
confiderable. s 

Before I can proceed to give a far- 
ther account of the Hydroyhobia, it will 
be neceffary, for the fake of method and 
perfpicuity, to defcribe the appearances 
obfervcd in fuch bodies as have died of 
the diftemper upon diiTeflion. 

First, then, the internal fuperficics of 
the Oefophagus, or gullet, has been gene- 
rally found confiderably inflamed. I fay 
generally, becaufe the late Dr. Mead has 
mentioned in the FhiloJo^bkalTraHfaBions,, 
the cafe of a boy of about nine years old, 
who died of an Hydrophobia, and upon 
diffedtion no appearances of inflammation 
were found in the Oefophagus. But this 
is a fingle inftance, and I do not rec&lle<a 
ntr-;. ■,:■.. another 

64 .A TR,>B,4TX"S.E. X^) 

another iUpon record to : this jiticpo^- 
hircori'es; of ajmoft every other cafe taking 
riofitq^pf tJii^.appcarantJjc a^ mofl: rfimsurkn 
able.': And this^ibiiahimation. has, been 
obfecved in the .iiomach and ij)teflines> 
and in. the menxhranesvinterpofed betwixt 
the cartilaginous rings of the q/ 
teria, or windpipe, by Bonetus, and other 
authors of authority. 

It' will be'obferved in the fequel, that 
patien^ts under the influence of an Hy-* 
dropbobia.vsx^ often difcharge by vomit 
a vifcid, glutindus^bile, of various colours^ 
a dark brown, for example, or green, 
frecjuiently J of a diiagreeable. fmeil, and 
often, very oiFenfive* .Much^r^f. this i^ 
often found in the ftomachv upon diflTec^, 
lion i ..AQd the gidl fcladde^ has. on thefc 
occafian^ ^ bcQn^ almpfl always found ,dif- 

tcndq4* with. IS thiffe. tsn^ious hale, of. a 

■ . * 

fimilar cjolouri :&nd ,fpajet;ime^..biack. . .' 

Tnjf . Pepcardfuffi, i^,,.a. kind ■ pf bsgy 

which inclofcs the ,, ji^^^t^, tqgeth^ ij^^th 

, its 

its auricles, or what is in beads called the 
H>iafEarSs and all the large veffels arifing 
frofti thefe and the heart. In this bag 
a fpobnftid or two of bloody water i$ 
^tfually found upon diflefling fuch bodies 
as have either died of violent deaths, or 
other difeafes. But in fuch as have pe- 
riflied* in confequence of an Kydrdphobhip 
it is found without a fingle drop of Va- 
tpr, or moifture, fo as to appear rehaark-- 
ably dry. 

THfe lungs are oWervcd to bfe pitodigi'^ 
oufly <liflended with thick blood,- ^ib ui 
CO have the appearance fometimes of 1 
inafr of coagulated Wood, deftftutfc of 
6erunw The caviti*s, or ventricles of the 
heartr dnd it^ auricles, eipeciaHy thi 
.right, arc obfcrved «o be full of concre- 
ted blood, widi litde or no Moifhire; 
but in the left ventride the blood has 
been found fluid,: But the different ih^ 
tervals of time betwixt the death and the 
difle&ion of the fubje^, may caufb £omt 
diffwence m thefe refpe^s. 

F I 

■ ■ 

I fiNj^Dr. Mead^ in the.laft cditiott 

of his Trfiatife on Poifons, attempta to 

^ablifhr a very iingplar theory relative tQ 

this diftemper^ and: to prove that« the 

aeryousL juice receives^ and convej^rithc 

inoculated poifon into the habit« Aflid 

Boerbaave has> in his conciie way ;of .wct« 

tiogy . insinuated ibmewhat of th^ jGune 

kind i and tbefe have been foUovred .buy' 

others, for whofe characters I have. ipKix^ 

regard. But as I cannot facrifice vnf 

r^aibn zxid, my underilxmdiBg to the Maner 

of thefe great men ; as I have not a tUitt 

of mind fuited to abftrufe reafonings on 

viiionsj; a$^. I. prefer a faithful detail , of 

fa£ts to romances, andefteem the evH 

dence of my fenfes, or what approachci 

Jihe neareil to it^ a better teftimosy. than 

all the ff^oHJ^g- probabilities that a warfti 

^aginat^pacan. fuggeft; I hope I may 

be G?^cu(eid from taking . any further: no-^ 

tice . of a theory I cannot comprehend^ 

ftftpr baMictg declared/ that r do not be-^ 

* * 



jeve one fyllable of the modern doiSrine 

tervom juices and nervous H'l/lefnpers. 

^R this it fliould feem incumbent 

explain, how I think this infec- 

^^ed, foftered, and propagated, 

jtely to infed: the healthy 

t a train of fymptoms, 

teemed the moft ex* 

.re known to be the 


IiN ordei- to fet this in the cleateft 
light, let us confider the appearances of 
the linali pox from inoculation. The 
furgeon makes a fcralch upon the /kin, 
very frequently not deep enough to 
bleed, or to admit immediately the 
variolous infefied matter into the 
i>lood. From this operation the patient 
perceives no inconvenience for about 
eight days, more or lefs j but about that 
time the wounded parts begin to in- 
^mc, and. in a little time to difchargc 
■^JluE, or Ichor, or fome kind of humour. 
■ F 3 At 



At this time the inoculated perfon begins 
to be fick, hot, and uneafy ; the head is 
affedted with pain ; he becomes deUrious, 
and often convuUed ; and thele fymp- 
toms continue till the vital powers have 
relieved the conftitution from this em- 
barraffment, by fmall critical and ialu-. 
tary inflammations in the cellular mem- 
brane, which from their firft appearance 
tend gradually to fuppuration, and which 
are called puflules. 

Let us compare this with what hap- 
pens upon the bite of a mad dog. The 
animal, with his tooth covered with fla- 
yer, inflids a wound, which very often 
amounts to no more than a fcratch, 
Tpithout opening a veflel, or drawing the 
ieaft drop of blood. The infeiSing Sa- 
liva, by this orifice introduced into thft 
habit, remains there without any appa- 
rent injury to the confl:itution, for a 
longer or a fliorter time, from one day 
to ten months, or as many years, if wc 
may credit the hiilories of phyfic. But 
-4* lb 

C A N'l N»E ' M A P>N?E Sf. ^9 

jfb^ 'ibbn as lh« eetitagion h&s itrade m p^o^ 
jgtc&, and altered the habit fo a certain 
^gree> the piurt where it wa® origixn^ 
received generally begins to inflame, fei^ 
terr^ and be painful i and tk«^^di&empel 
whkh has been already deicribed ccmiei 
gradually (MW o 

' Bu T here the compariibn ceafes yfak 
whereas the fniall ipox tern>inates hy'i 
£dutary crifis, the difteniperin queftion 
has very feldom been known to end 
dthdrwife than with the life df the pirty 
infedbed. There is, however^ fimilitude 
efifOugh in their propagation to juftify my 
comparing them together, and to render 
U* probable, diat they are both received 
1^ fb(Vered in the ian^ way, though iii6 
difierence of the poifons may render th^ 
C<Hi&quences Hot the fame« 


^ Here I cannot forfjear rraiarkingi 
thfett if the cxiftence of a nervous fluid 
l&d been provcdi which is by no means 
^ ca^ I|b(»ttld appt^heiid, ^t a fpirit 
a F 3 fo 

fo fihe'its^td e(cape thc-'ii6t5cc df tli# 
fenfes, to elud^'everjr artifice of the ttfo(\: 
artful and curious inveftig^tot-/ and which 
has been compared to cJe<Strical fi^e^ jxMik 
be contaminated fo inftantaneoufly, as" to 
pfxxluce immediate and fenfible effe^^ 
ivithout waiting on the poifon till*<"it 
pleafes to exert itfelf. And as after th* 
receipt of the infedting matter, the blood 
does not appear to have contraded any 
noxious quality, or to be in the leaft aK 
teredi after many days, weeks, or months, 
it ihould • feem extraordinary,' that it 
Ihould have' harboured for fo long atimd 
fuch a powerful inmate with impimity^ 

• But there is another part of the ma^ 
chine, neither fo much underftood or no*' 
ticed as its importance merits, which I 
think more adapted to afford a nurfcry 
to this, and many other kinds of conta- 
g'lcn, than thoft already mentioned/ I 
mean the Cellular Membrane. This BcK 
erhaa've has proved, to my latisfaftion at 
Jeafti tQ be- the receptacl? ot -the ven9real 



jhrfcdion, anodierspoifoft prtif^ag^tfcd ; bj^^ 
inoculation. An(i this is the known fca£ 
<rf inflammation^ : foppuration, mortifica;- 
tion, and gangrene, a& weil as.of mi^ny 
OF moft^ofthpfe 4iftpnipers which ard 
called €utaneous,^from a common piniplfif 
toa .tmboin thepox^ or a carbuncle iii 
the plague ; and therefore it mud be fuT-f 
ceptafole. of infeftion from -within o^. 
without^ or from both. . - ' 

-That the reader unlearned in anato-^ 
my may the better comprehend what I 
have faid^ and what I (hall fay^ upon 
this fubjeft, it may not be improper to 
make him acquainted with the mecha- 
nifm of this extraordinary membrane, fo 
far as it is hitherto underftood, upon the 
authorities of Boerhaave and CheJeUenp 
the former of which, in his preface to 
the colkiSion of authors on the venered 
difeafe, thus defcribes it* 

V ■ 


^ This membrane is of a vafcular con*-. 
/ t«ftwe; Mid forms innumerable cejils 

F 4 * com* 

/ >. 

e7^ xmPl^^mKl$^:i>n! 

jji^hil^h, the fat isJodgiecL Tlifefe cdls 

:dla«f fci4)€^lp of ^ prddigiotos difljeQti(:^ 

J^hf a t^ry fmaU difteading forc&<: In a 

^^!)f7pnf^ption the^ :ftre:ib mtach W^ 

f^lhat: th^ kaft traces ; qf them art ,)iot 

< peoqept^hle. When la an E^pi^ma 

f !thej(:a|tsi(|ift^nded. with air^ thajriwcU 

^.^OiisMv enornototoSf!]^^ alfo in ai> 

^ Anafarca^ when, fiilied. with water./. 

*.- ^' -I^HiS Ineinbfaneirtv^sallthcmatre- 
f able patts; df the body, ahd, by its in-* 

. ftyterpofkii)n betwixt the intern^ part of 
A)the, J9an» and external furface of the 
'^ Inuiclcs^ renders the fkin moveabk> 
,f whilft the mufcles Are at reft. Hence^ 
>f,wh€yr«,the mufcies which are moft in 

. Mnoftioni are fituatedy there thiis'-mfem- 
.ffbraoc is found to be toaturaUy thtckeffc, 
jf and ^moft replete with fat ; as ip vifible 
* on the breaft,: abdiJmen, baqk,i teiiis, 
^ buttocks, thighs, legs, fhoulders, arms, 
S $w^pl€i«, aad toedk* . ; But in thqfe parts 
> where, the . wufcks are ve^y fmall,. or 

* their 


« ni/hed with feilitde fat# thit m^ wtik^ 

< tQfdifts haye doiied^ that m: lliofe fdacei 
^ it is to beJoand^. Thwiathe htod; 
^ eye-lids, face» and fcrotum, they affirm 
^durt there is /oofach tiuag ^ butHow^ 
f cvericm>heouil7 ; fiir in the£(^ parts it 
5jr€aily;exij(ib> but is 1^ in proportioil z& 
f . the Eievafor Pa/peira Juperioris and 
^ Corrogator Brontu \% lefs than the Glu^ 
f tai. But as this membrane feparateS 
^ idle moicies from the fkin^ib it lies be- 
^ Ovidxt the muiclesy and feparates^^veiy 
^ individual mufcle of the body from 
^i every other mufcle^ that they may move 
^ upon reach other without difficUltyv It 
^ forms ahb vagina ijht^xhs) for the ten- 
f dons of the mufcles^ that ihsy may 
^ readily move backwards and forwards 
^without any hindrance. It, ^rdier, ac- 

< companies the heads and tendons of the 
^ muicles to their^gins from, and infer- 
♦ tions intoy thfc bmes, where it is expand- 
'1^ ed upon the cKternal Peri^a&H (memr 
« braxve tliat COVE'S tbeibooe) bones and 

* liga- 

f^ M ^TT/R E<AT 1 3 ]& • ON ? 

1 ligaments < of the joints, which it -in- 
f volyfes, and iniinuates itfelf to the Vif-- 
f cera (internal orgaps) under the Menin-* 

* V 

. , vB^^iDEs the, Involucrum,* or -covdr^ 
Ving, which the. cellular membrane give$ 
^ to , , . ^aph mufi:le^ « as abovemeri tioncd; 
^^j^very . individual . mufcular fibre . is 
* clpath^d: with a produi-tion thereof,, by 
fythe intervention. of: which every .fibre 
f is feparated and, diftinfl: from ,. every 
^ other fibre. This . membrane, there** 
j|,foj;e, on account of its incredible, ex- 
/^aftfipn, and the communication o£-it$ 
^, cel)s v^ith each other,. carries on an in^ 
i.tqrcourfe between, the parts of the bo^ 
f dy the moll reipote jfrom each other; 
f. betwixt the Ikin, for example, ^nd -the 
5, marrow of the, bones ; for as it reached 
A/rora the fkin. to. the external Period 
fjlaumi and as the matter which forms 
;*.the marrow is conveyed to the bone, 
,^anjd a portion of it reconveyed back 
;1 ggaia by the vej^els of .tlie Perio^anntf 


G A N I N E ^ IV* Attif^'fe IS. f^: 

* the way is obvious how thefe ttttwtc? 
^ parts may communicate.*' ' • . s v* » 


' BoERHAAVE fays, he is <»1»4nced^*[f 
' this ftrufture, and the ufes of th^ Mem-' 

< hrana Celkikja by irttohteftible ■ eX^A-i- 
^ments, and that the kno^vlcdge of: itti 
^ irtdifpenfebly neceflary 'both for^tindelr- 
' (landing and curing an ihflammatibfi, 
'r^uppuratidn. Gangrene, Scirrhus,^GiiH- 

< ccr. Atheroma, Steatoma, MelicerBs, 

* Sphacdus, and Dropfy. ' ' ' 

^ GrtESELDEN fa3rs, that the celb of 

* this membrane communicate throttgh- 

* out the whole body fo much, that from 

* any one part the whole may be filled 

* with air, I have feen two cafes, fays^ 
^ he, where the, windpipe being* cut, and 

* the external wounds being' clofely 

* ftitched^ by injudicious furgeons, the 
^ air which efcaped at ' the wound of the 
f windpipe, getting into 'the cells of the 
' Memhrana Adipofa^ blew up the uppeif 
^ part of the body likfi: %. bladder, : The 
- *Uk5 

f Itk0^1tccidcnt^ £33^$ he^ I have jfeen front 
^ai broken rib, . where' I ^ fuppofe the end 
♦>of the rib had pricked the lungs : all 
*.4feefei peifons di^d* 

^'■•■f^in^ thefe cells the water is <*>ntained 
^iiti atai Anafarca^ which from its weight 
i^fffli££Ils thddepending parts^ as the 
1 dirt in the formier cafes^ did the upper 
i|>ertS:; and when thefe cells are very 
•rfifli/th* water frequently paffes from 
< them into the JiMommf and after tap- 
^ pfaag', tho' the limbs were ever fo full, 

* thiy • will . almoft. empty themfelves ia 

* one night's time* 

:: fiTai^smcmbiattieis the ufiial feat of 
^ kmpoitim mation and bc^ls> in both 
^mbi<^^2Xatc tminterrupted always cor^^ 
*. todis> a - hdc hi tile? ikin, from whence 
« we may learn^ ^at thie feeft way of. 
^.opetiing impoMbrtiations is by a hole; 
^.fltit# that too a» neat the time of its^ 
** hrbakrng naturally as may be, that na-' 
* toi^may make; the utmofl advautegeo^ 

« the di&hftrge. : Th^m is fomsUrMkit 

* large Jdnd of boylji i>r carbuncle^ iadthi* 
^ membrpie, which ;6lA makea ;aiiat^ 
« Houghs and a numbet of {msll hdo 
^ thro' the ikin> which in time mortifies 
« and c#s oiF^ hut the icmger the floi^h 

< is AifFered to ren>ainr the more kt^ <ttl^ 
^ charges^ and with the more advantage 
^ to the patient ; at the latter end^ of 

< which calc» the mattor hai^ a bhiodf 
^ tinfture^ and a bilious fmell^ • exai93f 

* like what comes from ulcers in the 

* ver> and both thefe tales arc att 
^ with fweet urine as ikz Diabetes/) >n " 

To what the two laft quoted author^ 
have faidy let it be added^ that there is a 
perpetual intercourfe betwixt the blood 
V^flels afnd the cellular fflen&brane, Jdod: 
cofi&M^ntijr betwixt the^ontentsofboch^ 
the Uood and the fati and that the fat jen* 
ters the compoiitioq oftbe Bdki ^ portijQfi 
of itbeing coaeeyedfix)«tits giJcatf c^epta*- 
cle the OmentumrVrhick m beaAs jbs ,i^(id 

1^ Lfqfsl» the Vtna£prtarmt (th« Iwge 
. ..i veflcl 

V.-*'. 1 f «,« 

7« /AiTREATlS13 OliT 

vdOfd which conveys' the juices to iht 
4iwr) by veffels adapted to that ufe; 
HeAce^ when fat horfes are rode, or cattle 
dtove very hard in hot weather, rthe fat 
lu^fied by heat* and impelled into the 
liver too copiouilyi burfl:s that organ^ and 
tht beail inftantly.dies. 

ir. ■ ': 

!.» Xhsse things ;being premifed^ I think 
it no .difficult affair to account for, the 
r|jrogrei^ of the venom, which i^ the fub- 
jciSti pf this diflertation, and to . tracer ; it 
ii»m the part where it firft entered the 
body^ithrough-iaJl the fcenes to ;the ul- 
timate cataflrophe, which clofes the tra- 

! I apprehend^ therefore, that the poi- 
jfonou? Sii^a adhering tp the toe)th of the 
^d dog, ,i^ immediately communic^^ 
to the fat refiding in one or more of the 
jcells of the menibrane juft defcribcd, 
which ufed to be called the. Membram 
^sAdipefa^ ■' but . now - more .generally the 
M^mbra^aCdlulafa^ A fcratch^i^ fiofficir 



€ttt for Aiapui^ofei >if it orily fftifoftli^ 
cuticlci or external ikin^ withoot opent 
ing a iingle' blood vdiel^ or 'drawing ^ii 
drop of. blood 1 for' this fubtile pdfeiS, 
as well as the venereal venom^ U-t^p^^ 
of entering the cellular membrane, Wh*h 
applied to any part, not covered- With, 
>nor defended byi the external fkin, o^ 
Vutktila4 -: Thus I -think- it is receiSred, 
widr-there harboured for a'lbng^r iH 
fhorter tirafe^ according to the degfe^W 
the infeftion, thfr-heat of the Velth«{, 
iKe conftitutbn of the patient, ^^i3>rA'^ 
thod.'of iiving, and a dioufand iiiinQti(rtf'« 
able drcumftances, which miy ^sitiS^ 
. accelerate or retard the progrefs of*^ll^ 
canine venom. 

t j^ iMi this ^fifft ^ tc<;ftptaick> " like< anf^^tivll 
gucftj it ninfedU i the 'Contained M, ^a*^ *^ 
kind-of kavcn, whidi: communkiatesr tiKe 
contagion to' the adjacent cells^ and tiiefe 
^ain. ta otheri^ >till the whole mafsi of 
fat * is thus' akertdy ior^at' leaft a ^^udritfty 
Npf^iti Efficient' to pjtoduc* k diiteirt^jkft^, 

re/CemhUog. j^at whid) tko, wmmi hm--^ 
bour^ under* which communkat^itont : 
gin;^U]^ , (he^ venom* 4nii ; tvhoie . i jtuMt . : 

twi;^t.t^:>l0o4 a^ the cdytidiiBDjnanHi 
hv9fic ^ fjtti :it ig wt iprabiablc it jdiouli : 
f&ape liifi €Oi3itogi0o i /luid y^:;tbere;ii 
fi)i;i$jp ;i:^aic» toi bdk«c>. jtli^t Ji ik not 
initdtfjafi^c^ed evea a&cr ^v/bmtkkig 
ottl< Oif (tl:^ <difl;eittper> as k has all tlie 
tefrkfi iMf Joeing le^i^toKly i :gO€d^ virhen 
Iet^p9t f)£ithe :&p(i)r^ . cifiren &£^ ike dfr# 

is Qmninota bonus % good ia^a^iQigr^TeipeaiSl) . 
in appcarance5* But in -the progrefs of 

beiagviiimetiwMi^Tei^Sjiiaejn andidiick^ 

and at K^Cos^.,t^%^^^ 

Crmr, or gore ; fo that it fbould ieem not 

recQHit aifcir^l itstpodlumi&an itlf^oiAai . 

> that 


ihat has'hiAcrto rendered the cure fo 
difficult, artd difappoiiited" the pradH* 
tioners in all ages in their attempts to 
iremcdy this diftemperi For whilft they 
apply to the blood or nerves> quite in** 
iiocent of the evil, the part aiFefted is 
neglected, and the contagion fujBTered to 
proceed unnoticed in its proper refidenccik 
It is therefore incumbent on us to look 
a iittlc. further, ahd examine whether 
there may ^ aot be fome other juices itt 
the body, Jwhidi this venom may afFe6lv 
in fuch a nianner as to excite ia diflem<»- 
per^ and uhiqiatcly vitiate the blood, aii$ 
diMrb the ;l^its . By fpiirits L mean that 
part of the corporal fyftettt; Wlirkh coriveyi; 
ieniation and 'Motion, Without pretend*^ 
itigiio underilaiid how or in what man^^ 
nerthefe are. performed. Abd I would 
chuib toliave this remembered^ whene^ 
ver I mentibn the fpirits dr nerves^ • 

\ It has heal- '^eady ob^(erved> that A 

eon&krable qiii^fitity of fat enters the 

c^pofition of the bile,^ a fluid of th^ 

*♦- C moft 

moih extenfivc u£e in the MSthal icBCdno^^ 
my^ and uith which iSmntA'^f f^iHfdy 
is fappliedi bythe Liveit in immeinie ^usufi* 
titjasM I IK^W' ' when the fat ns f ink£bsd 
with. contagion^!! probably » in proceftriof 
dme>:the- bile; mufi partake <yf 'it^fitf 

•Jtxau xo(Ugog^ x»mp mvj ^dn- ^it birdfiJBfM 

fsaii egg. '^ '••': '; 

iriNow itrififfCztiemciy cvMain^-thatinioft 
^€|:te^ilIId«t)tbe' infktcisecrf of thir Ai4 
IbfOfieiv ^iichacge;' « By ifaxbit . a- .viftad 
XeNt^ib^)fii£ii£ ^vaiiousfr^cfdoost^: frequoiidjr 

i^^P^^f tr i^fti^utity.^'jtw^eous dkfi^ 
i«ir«ir)»t^lM^ bo9a £QJulKiib«grfiat plenty 
lfliJth/9 f|oi)»a^i aadfdtthg^lbbladder liJH 
^dpdi.^i$bvy»&i4. hUf^jvefy fjrequemly 

. black- ^ Vt';:^ri iUs^ttV'i ^VHI 5At«: I. . 

• i . '•» 
ri It. 

• . > • • ■ . 

R.;^,jij(tu$;jfvJIW3f« i»# <*i6r»«.^ may 
ijluftr?if,.j;hft> fr^enjt Ij^lyd^, ,^%t: from 
t][t? very infai^cy pf thje; fn^cinal art to 

. \ this 

Qi. i 

this hour, A/aci tenacious Hie has been 
gfiacntfl)r ^oeni^di^he ''gfeattli<hia& 'of 
aU€natk)ii;of>ithb mind ;i and:.t]iiia&aiine^: 
diaiiim wliLch di^bhrei it, ohdzthofe purges 
whidi:(carr)t it.cmt^ofi^the body; drnvejasi 
generally/ b^ I ^thought to ccmtribu0rtbr 

, * *. . 1 . - . > . I f % / J -• iJ « j ■ • . i " /1 1 ./ J- .* 

Txri:proceed':of]?faisrbik b^ing ^^kmdpin; 
the (il:etoa£h^$hii£(:a!ten5dn^ft(^i^kili^ 
C8}>fllkte^:dantlIfihfaBrf£tClplire ksieinftenoe 
su)b idtscnateofbib^ ii^iigks : £ ibsdbtetoe rf 
€ondqAe)othrir at[Ii6^'»ibd^ Q}>oq 
dirpdreUrtr dgeri^ Hirhicivajhdircelii thtt 
obao^-'^tidrtihat^'im tEerliyiBiv^h^tGe^Utdt 

fat that ehtdm:id^I^m{$d&t&)di^^'Ofilhte 
bile ? What makes this the more pro- 
hiUe is, thati froii certa^-*e«fily cdrtciiv- 
titilei changes An' the fiifitif y " fi^fteaiw, a(lmo ft 
every fymptamlitaf the eatfirrtr Madnefe 
may be accounted for and explained. 

G 2 The 

■• i" 


» • • • • • » 

./rj<«.bilc> 'tis -^eir^owiv when* iit 
ite joatuxai.ahd fulutaiy ibitej^ is a ilqid- 
q£,^iitmoA: importance to thie limitn^ 
machine ; 'tis ceirtain^ that it is fubfer^ 
vient'tdtnasiy aftions, whicfay were they 
to languidly or ceafe^ gn almofl: imraedi-^ 
ate period would be put to life. And it. 
id etq4a% ceitaiii^ : that the .bile is fub)Q& 

cfitc^BBitiand iritwnalicatifb^ ;tbat render 
|t,, !iniflndl>c4i a : benign fldid^ a noft de«4 
ftcN^ll poifon^ fkaroeljiiir^eHorkL as^ 
mp ia;^if»iiiii^nc^^ !>}£ t}ii» .ihould^ >be ;iii 
theledftrldoyfatedpl: mieic iki^ict^fZ ia 

4kintf:it^^tntno Corporis^ of which il^^ 
$9 > tufaoitatKP^ in th^vMcdidnal i>i<^iat|4 
«^/iyn4i^.,|h^dr|ipl^^Lj^^ . \ : 

r. ' r 

^ ;/•.* t 

i;, ... 

. I M e'^T! . nK)t,|»r0cetd w&hout fcnaiark:^ 
i^g ^g^ that the blic is fecrc.ted in the 
rJUvtr ib kntnenfe >q^aii|iti ;; > •: 

^4 ^ .• •. f 

Ci^mKJ*EL%^l)*I%S%. ^1 

* I 

•*• E^ii« US ho«r j)?oiJ&3 td'take k vieW of 
ihi" rymjjtonil^'' of' iJie' Canirife "W^^Afefsi 
t^en the caufc 6ieft{ 'itfelf •^v^'idfiVity 
fttffident to exiiS^e a (Jlftemper. ''''•' - ' 

' -'Wh^n the iiifeaion lias '^eeR'i^mci 

lyfifcjptdtn of flic appi:oachii» tlifeafe is a 
paiii in the part where the irifd^^on wki 
nrft received, which is propagated fboa 
to 'thfe a^acerit partS'j ihd' if the wound 

arid 'Dac?K of the 'feme fide. This pain m 
fBm6'i3 fejitrenieiy acute 'ahd' excri;iciai^ 

irtay riof be eftedm^d* it certain ^cJiaenoftiS 
of the -diftem^'r/^aihcf'put nave 

received the irifediion off^'thblr guafo^ 
when this does not appear, I muft/e=p 
mark, tfl^t WHcn the contagion is rer 
eeived witnout any laceration o; any part 
^ the Ikin,. but by the patent pores, a? 
ty rpuch handling the foaoi, or the ap-^ 
^licatioa of it to fuch parts as are not 

G 3 fivniihed 

furniflied with the fcarfe, or external 
ft:in,. as the lips, tongue^ -or any. part bf 
the TOOUth, by a. kifs^ "or pthcny^fe, f J 
am not certain, qither ftpm myowa'tsp^ 
pcrience, pr the ohfervatioijs of oth^tSt 
that this pain is a prologue to the trage- 
dy, or that the diftempcr may not csi/tae 

on without it, jyi^h^abpuVJJMr'.to^ 
time, the i^Qjinded part Iwgrn^ -to feftef 
and he fore* , . - . » ' 

» » • 

^ . .In tiusiJy^bptpin I mpft confefs there i? 

ft Wgftfpga^Q ^bft?ur^..t9 b«^' iPr«ifdy ac-r 
CQijBted. for. But in order to fajCiJitiitQ 

ap ^xplic^tiftfi .of..jt,-;^e,tfitijl>9 t^m^m- 
bcred, . that .the yqry, ,{ami^ J^gi ijiappens 
in theijJQculation jfoj.^^jie.fe^ 3nd 

in apother fpecics.^of iiv)cx4?<?o;^^:: that of 
the. venereal i^fedHpn^ ,.ifor i^' both thell^ 
cafes,, however different in their iiaturcs^ 
the diforder caiifed? by .hpth^ ^o/editiox^ 
firft fhew their aftlvity in the very places; 
where they were, originaJly receiyed,^ 
In the fmall pox. the variolous ppifoa 
firft rnanifefts its roalignity in thp?yetrjj 



CAN 1MB M ^la W KS S. S7 

arm> Or wherever the jioHox) was^ in^t^di 
In the. venereal difeafc, if the Glam Pe^ 
«£f is firft infeded, there the firfl: fympi* 
tooispf the diftemper. gencrajly give tHo 
fifft alarm of .the ^ppix^ajohiog jL«^^. If 
the nipple of . the breaft, the lips, oi 
tongue, firft receive it, the offending part 
i& firft piiniihed for its delinquency. -' 

Let it alfo be recolIe<fted, that in n 
ipecies of ulcer which occupies the cel-^ 
lular mcnabrane, taken notice of in tha 
paflage quoted above from Cbefelden^ the 
frndl of the difcharge much refembles 
that from ulcers in the liver. .Whence 
it fhpuld feem^ that there is fome com-- 
munication betwixt the liver and cellular 
membrane, by what intervention anato- 
mifts have not given any iatisfaftion, and 
which I do not pretend to know. But, 
ypon the whole, an alteration in the con- 
tents of thexdlular membrane is likely 
to .he gfeateft Jn that part where the ve- 
Bom was firft received^ . and to be moil 
permane;at. ; /When the jyhpl^ bile, 
;■;' G 4 therefore. 

all over tb^il)ody» :that part where the 
obilru£tIoii, or call it injury, is greateft, 
lyill be.tbe rinflfti likelj^ to jcocive the firft 

,; T*i? ::fymptom»^ wthati^lappear, 
HYj^^di fooncr or later fucceed the pre- 
f;cdiilgf: arp X^iStudp, a feniktion, as. it 
wei:ei Qta}oa4 or weighty and ina<5tivin 
ty or torpidnefs, with reipc(3: to mtifcukr 
motion ; difturbcd fleep, attended with ^ 
tpf rifying dreams, couvuhions, and dart- 
ing3 ofr the tendons ; perpetual xeftlefs- 
nefs ; figbingr deje,£tedne6i» ^nd dcfire of 
iijUtude-. : . < - ^^ *> ' •' 

Trt^ifS, traia qf fymptoms isitaken from 
^Qerbaayey accordiiig ^$o >vhom thefe 
cpnftitute th]q,i|rft, flag«tpf;the>diftemper. 
Btit as this Qelqbrated, author thas (X)lle(3jed 

)^^4 ,PHf . .t^#^R: ^y-^ty ^ 'fyn^ptom that 
occurs ;iii, :amJbpr^, .thai:: bavic ^ wrote upon 
\t> I m\ift apprife the reader once more, 


ia certdia caf^s, iome iJ[) <)^Ws. 

' « • i » i- 

Now Bono iof thefe iymptdrits ar*^ pife^ 
culiar to Canine Madftefs* Thcykll 
frequently occur before, and during a bi-.- 
liousr Diarrho^a^ or purging excited by 
putrid ': bile in the ilomach by whifch 
they are totally cured, as fbon as the bi- 
lious forde$ are ;difcharged eitlier by vb<^ 
piit, or flool, or by both^ 

*These alfb frequently appear jn the 
beginning of many fevers, and ieldom 
fail of being removed by a natural or ar- 
tificial copious difcharge of bile, either 
upwards or downwards. Of this I have 
feen innumerable inftances, wheti my 
powdei;s have been tdken in quantities 
fufficiefttJtcy Excite a vomiting or piirgt 
ing. It is therefore probable, that they 
are caufedil!^ bile in the ihwnkch. Duo- 
^enum> gall bkdjjery or liver, in the ca/es 


•■..,. .. .». 


laft nientioned; andiif in thefe^ whytiiot 

ia^ie* begionibg ' of CaDine^Majdaers I > . 

• • " . 

Many under the influence of Canine 
M^dnefsin this fbage> have.compl^bed 
Kf being afFefted in their dreams with 
horrid, terrible ideas about dogs : /But 
this ii ; do not Xqok ; upon as an efiential 
ooffcomitint of ■ the diftemper.' > Tbeteri- 
ror excited by the bite of .a >mad dog as 
uppcf^oft ity tb^ mind ; and this the 
imagination reptefents to them ileepi^ 
or waking. If an equal degree of danger , 
was threatened ^r6m any adkibn of a be- 
loT?)ed fifter,- or mifirefs, I doub( . not but 
the imagination would be cmpjoyed about 
theie, as jnuch as in the prefent caft 
about dogs, ' 


XhERE is another circumstance omit- 
ted by Bderbstaviy and not taken notice 
of by: his eixcellent commentator Fan 
Si^iaUn; asi I. remember, : and »»yet it is 
very remarkable. It is, that all the ex-r 
terhal organs of fenfation are rendered 


moft eafilyi fufceptible of imprcffions, fii 
as:t6i rcn4tr almbft evcty objfeftithat fire- 
fentq trcdtdefome. Thus the leaft mo«* 
tioit^pfi the: air fe iineafy, and the very 
ligfac bdcoraefr horribly offenfiVe, • '-"t 

• • " X 

• MeaO' takcs^^notice of thi^j ami the 
girU Whofe. hiftory^ Khali hereafter i^ 
late,. could not bt^t the light, 'the* her 
eyes'wcre (hut j and fhe was obliged- tS 
covier' her face with the bedf^cloaehg/ ifl 
order to avoid the uneaiinefs it gave her;^ 

Wirjt refpedl to -this, let it be -confix- 
deredir itbat in drder to produce a difa-' 
greeaKe' fenfation froni objefts before 
pleafing, either the organ muft be afted 
upon more forcibly, or it muft be ren- 
dered fenfible in a greater degree to ex- 
ternal impreffions. It cannot be the for- 
mer, becaufe the air and light muft bfc 
nearly the fame as at another time. It 
mUft, therefore, in this cafe, be the latter; 


■ But 

. .^t . 

ft - A ^ni E ATI S'E- &Vf " 

Birr the fime thtng^ happens, m^feiinr 
degree, m various other cfiftempcrs; 
Thus die ienfation of maniac :uftd ^ire^ 
nitic patiotts arc frequently extrea^^ 
acute, and the organs very ienfible of 
the adions of every external clt^iStl 
Thus; atfo^ in the beginning of manx 
fevers, the air b^cx>mes diiagreeable, ntd 
the light ^xpefiively of&nfive ; and a co<* 
pious ' diicharge of yellow or green bile 
by vomit, almoft inftantaneoully removes 
thefe iymptoms, as well as the head-ach 
ufually ajttjcnding. Ane we, tfacrefbVc, 
to fay, that in this cafe the very feniible 
mettibranes of the ftomach, and all the 
parts about the Pr<3ppordia, communrcatQ 
the fenftyons they receive from an acri?' 
xn^nlcHis bile, fo the whole iyfterii of 
verves'? Or, that the bile become ex-* 
tremely ftimulating^ and poured all oveir 
the habit, acuates the organs of ^nfa?^ 
tiQii, and renders them fufceptible gf the 
llighteft, and;iiore affeifled by the ufual,. 
ioipireflions ? Or ratjier, ^that the bile 


^ihg acquired foine new qualities^ be^ 
gin$:{idw to. a& upon the braini andjtd 
render flie entire Ofrgan of feixiatlcyD^ 
^ence 46rived# iliorc; liable to be movc^ 
by all e^ctem^l objects ading upon theg^; f^ 
The moil general caufe of inadnei$ 19 
£dd iQ^ be an .obftradion in^ and a Ph-.e^^. 
nitis is^ adhiaU; an infiammatioaof^.th^ 
brain. - •:: 

* 4 

The application of what 1 hdVe Juft 
laid to.thdfe fymptorhs of Canine Mad-*; 
hefs/is too obvious to require farther 

"' ' ■ ■ * ■ . ■ 

The Uood taken aw^ in this flage^ 

being In appearance perfedtly good^ feems 

to intimate^ that it is yet not much vir 

tiatexi by^ the contagion. In this flage 

of the: £;amne Madneis \ think it always 


% QaSi now proceed to examine the 
iecond Aage/fis it; is called by Boerbaan)ef 
having lirft remarkJe^j, as I did before* 

i ■ ■ ' with 

wA -oipea: to ^er:^i^b^8to4luti;:«2t 
^uj^ :^ ^ipt pftei^ appeal:. 'uk^iSfCjU^foti 


cgjfeigsi^tK^^ of . a^ rbite^ frpoot; . jiif i qwa 
Dutch dog, that had none of themxii^ri 
cq)t great dejeftion^ and a lurid afpe<^. 
H^ had BO; d^ead of ^wjitcir, /oir I- faw ^pm 

3vith great pleafure and: fa^is^^ipp, bq^ 
long before he died. This pa^Pii^;^fWas 
not concerned for, and only faw Ijim 
9!P<:€;iby; ^fcidentv, . ■. The. jadthofl* hciJJur*- 
f^iedy ^never jcjieW:^. jthat X. rnp^cnibgiujr) 

Jjf tfe^^fwpnd-ftggCjthciiijalJtliid ibovb 

which are added, a diilrefsful. oaibArio-* 
ture, or tightnefs about the Praecordia i 
a.c$if5cw)t rcfpirsatl^D^^.attendcd \ttit&. fre- 
gjq§jiX%hing;;:;a\ii6arfiw:> and^yaShfedfiwI 
Jiempt at. the. llg^' of watcavi cy^amy 


CAN IN B MA»D»rrESS. fif^ 

liquor^ landietten.'of ariy i*hing- thatii©?. 
fledts the light tike aririirrof ; total ' liffk 
of appetite, whilft yet a poflibility rc- 
m«ns: of tfwAllowirig" folids ;: incrtriiWc 
anxietyi i tremors, andicoiiyuliionsr klihodb 
inducing^ m^idnefs; updn touchiDJgfaoy:li>4 
quors^r.-cfpcclally fwitk theiips jjind iobgticj;: 
a difchtrge-of very- vifcid darktcolbulrcd 
bUiou6^y&r^# or porraccous (green) ' bllc. s 
heat j • fevers wan t of rffecpy ' a Pn^piitn^ 
and a ferics of Anafual, ftrangc^ difturii-^ 
ihg' thoughts. ' ' . 

I •■■(«• '' 

* ' Most : of thcfe fymptoms appear *» 
many bther diforders befides ''Canine 
Madnefs. ' In that ciceffive voniiting atid 
purging^ fo frequent about the approach 
of autumn, which SydeuAam elegantly de^ 
fcribfes xioder the name of Gholera. Mor^ 
bus^ the ucriraoni6u^ -ibfle, ftinvulating; 
the nerves of the ftomach and ihteftiri^s^ 
and all the adjacent parts, excites ftric- 
turei difficiiky of refpiratidn> convullibhs, 
whicb'-ewr fo Irttle xieglefted bec6me 
i-: ■ '*^ ^' * . • '"'/V •' ' ifatal. 

••>'; • i' 

.'. . -tr!a 


fyal, and much the fame tFain of (ymp^ 
tofxis as thofe delcribed abore. 

''t^iy the bile brings about ill fhisr 
tion&fion in the body, becaufe when thi$ 
is brought away by drinking copioufly. 
th« chicken water defcribed by the fame 
Sydenbanti and vomiting it tip .zphi re<« 
peatedly^ and by frequent clyfters . of the 
iamef the diforder is in a very few. hours 
perfedUy cured « Upon this occafion the 
chicken water diiTolves, as it were^ and 


brings away the acrid falts of the bile, or 
dilutes them in fuch a manner, as to ren*- 
der them no loiiger ofFenfive to the ten- 
der nerves* And befidcs, the genial 
warmth of the chicken water foments 
and rela;{ces the contracted and , convulfed 
Derv6s» and nervous membranes^. and re- 
moves thofe painful ftridturcs which ex- 
cite ipafins. 

Many poifbns are alfo obfenred to 
produce nearly the fame fymptoms, by 
inducing pain, fickaefs, ftri(3:ure, . and 



toniiilfioAs. And ' I believe ho pfaftl-** * 
tiorter in phyfic/'thtit his ftieh an Kundrea 
patients need be informedi that in the^ 
hylteHeal parbxyfins of wdtften, and the 
fits of hypckrhondriacifm in men, all the 

. - ■ ■ ■ r 

fymptoms occur, which are mentioned 
above 'as attendahts Upon the fecx)nd ftagfe 

of Cariirtci Madnefs, th6' dread of watci? 

' ■ " ■-*"■'■ 

only excepted- And thefe, I am certain, 

frequently arife from putrid and acrimb. 
nioUs filth In the Duodenumy or the bile 
in the fame conditipn, or fome way al- 
tered from its natural and /alutary ftate^ 
harbburiilg in the liver, gall bladder^ fto-* 

mach and Duodenum. 


• . . . . 

Now, if the bile may be fo al^ 

' ■ . • . . ■' 

tered, as to become capable of brings 
ing on fuch fynijptoms in other cafes, 
why may hot the fame bile, poifoned by 
the Canine Venom, induce the very fame 
feries of fymptoms in the Canine Macjr 
neft ? IHo hoi fiippofe the alterttion the 
Ibild unaergocs, or the^ acrimony it con* 
traits,' the fame in all thefe cafeSi ; %r I 

H think 

Xhmk it m?y 4evi^e a !wJtItudft.of:^f«!« 
ffpin. a i|#wl ftatc;, and; induce fyjp^ 

aq4 events^ tho' in general fuffiokat^ .i^ 
mi}af 1^ difcpver their fourcc, 

« /• -i .■ « « • > , ' t * k . . . « . . - I, ) • • •* ^ ■ V » V • 

■ ,^^,.fymptqti\,,Q{ this, fiifpf4ffi» 
^Ia9h k^s jjjpen, n?pft paif tipttifr]^^ < ^ganfe 
pi TiyJ^icti has beep always (tl^q' f^dy) 
^eav^ its c^araiaeriftic, , afl4 tftcw* 
j^n^ce it,hfi8 ^qijiredthe naqae :of i^ 
4r^p^ia» is. jthe, dread of watep, or flui4% 

. In order to account^ ik^ iota? ^\p|^&^t^ 
for this extraordinary circumftance, let it 
be remarked, that there is a moll ama- 
zing, conpeiftics^. beitivjixt the mipd jand 
the bpdy, infoinuch, that the body i? in- 

^^^'^^^¥ f^^^^^^^y idea? arising ia 
l^e.m^^^. and the.min^, in its turn^ a^s 
it were, jpip^jtaaeoufly, and .wjijtjhout a^y 
previous expedience, confciQu? pf the ^ij-^ 
fations of the body, (q, a? to diftingijiitt 
v\r]^at. will 9pniniynic-4t» pain or.jj](e.^r 

•cial. " This kit: is what is calkd InJiinU 
ill the brute creation^ of which I do ncit 
thMk; thii humaA fpccies totally dc- 
^tuite. ' : 

J • 

.With refped: to the imprcffions the 
jmihd mlfces,upon' the body; 'tis noto^ 
/ JTOU8, that they ibme(imes irife to a pitch 
of ridiculous extravagance, when the 
imagination fuggefting fome unaccount- 
^k chimera, approaching nearer to fblly 
.than madne(s^ adts upon! the cprpored 
organs fo, , as to produce extraordinary 
<oiaii3^6tions in them< 

* To explain my meaning by a few ex* 
jirtiples, the following may fuffice. 

. . Some years ago I was callbd to a lady 
^advanced in years, whofe difbrder I do 
not recoHeft j but I remember it wai 
iucli a one as did not confine her to her 
bed, and was attended with no com- 
plaints of the ftomach. She earneAly 
petitioned ^ me .to Order her nothing 

H 2 that 

that was nauieous. I c^irefted a ju\eitm 
BriJiQl water,^ Rhenifh wlrie, aiid fihe^tfi 
gar- The apothecary brought it : a'l^t^ 
^lafs was filled out in my pfefencc i^'ttik 
applied the glafs to her nofe, and fmell- 
ing it> upon k fuppoliiioit that it was 
naufeods, took up a bafbn, aihl voinitek 
ti)l it was half foll^ without taking iftc 

TrfERE is a remafkable cfafe of a gen- 
tkm(m^, who had been obliged td'taicc 
(o many -purges and vomits, in confe-* 
quence of fome misfortunes attending his 
amours, that at laft the very fight of his 
^pothccaty,. who^ brought and admini- 
ftered them, had the effedt of an emetic. 

In regard to fimilar aftions of the bo* 
dy upon the mind, every one who has 
laboured under a purging, either from 
putrid bile, . or putrefcent aliment, either 
^ fiefh or fifli, taken in too large cjuaii tidies^ 
fo as to produce a furfeit ; and whoever 
h.^s experienced a fever, muft recolifedti 



tbat under thefe circumftances, fuch im-^: 
preffions have been made on the mincli ' 
that the idea of a roafted lobfter, ftrong- 
leop, or any kind of putrefcent animal- 
food, and more particularly the light of' 
ir, was unfupportably naufeous, without 
learning from experience, that fwallow- 
mg it was either difagreeablg .or pre-' 

This and many other inftances to the' 
fame purpofc, which might be mention-' 
ed, I have always looked upon as a kind' 
of inftinft, importing a prohibition or 
warning agair.ft fvvallowing any thing 
that would increafe the diforder ; whillt' 
acid or acelbent fluids, which contribute' 
to the cure, are eagerly coveted. 

I fHiNK, in all the dlfledions of thofe 
who have perilhed in confequence of 
Cj^aijine Madnefs, a very few only except- 
ed, the Oejhphagus, or gullet, hae been 
found inflamed J and when no inflamma- 
tion has been obferved, it was probably 
JI 3 tender 

i9t: A i 1 R E A T/I S3S : ' ®<NX 0> 

tender and foce» either frcuti k dikharj^ ^ 
op! thi^ :e^vi:»:)of ithe; noaddm .bile^i oc.aa - 
iBCf:pgfe4:^^0lGbl^iHty. o£ th'e(;iu5rv£si sodi 
tkfhft«Bo^k«»t)cett;in.tBu4 iain&oo{nii«i; 
tl^ATftMhe-jthfpat i8.-4l% generallys JJibiftL-^ 
5f^«$» it. hfts.h9e» QbfeBvodj.that per£bn« ", 

m9^ a41)p9ffibk q^>fits to dnAk> tbo' wit)^^i, 
outefFcdi, have immediately after pcrccivxl^ 
their ftomach to fwell very confiderably, 
not without pain ; ahd moffc patients haVc 
h^^ .a%^c?lt.<:oftYuIfQd. upoi> touching wa^ 

t§r> or.^^yi fl^idi^ widi their Jips*. M9y> 
i^, th!E}t€J|<SPei, the local 9fic<9ion of thsi^ 

body in^r^fs upon the. mind a {pontarv 
ncous perception or prefcience of th^. 
eflfe^bs, . Uquor? would, have, when. they, 
come in .contact with the tpnder and; 
excoriated membrane of the throat, Oe- 
fof>h3gu*, md ftomach ? And if fo, 'tis 
ftqt e^tra^ordinary, thai the idea of fluids 
£hpivld.!?3^cite averfioD, terror, and all-thcr 
(Kxnfcquencqsv . . , . . 

I. . k 


T 1 

C AN I N« ' MA BN E S i i-cij 

... • . ■ 

• ''■ ,• ».• ■ . t . • r , .^ 

•'**■• "' .. -T . '$. J 

In confirmjstion of thisi pefrmrt me to' 
retnark, thdf a butlter of Sir R6betfWdt^\ 
pal^Sy afterwards! Lord Orfbrdy havittg* 
^v^lowed accidentally a bbttle of j^lixir- 
of vitriol; Had for fbttie days as- ^reat Utt 
averfion to liquors, as was ever obferved 
from the- Canine Madrfefs: ' th?s^ I Aid 
not fee, but relatie uj>on utidoubfed a:u-; 
tKoffty: ; '^ 

ANOT'ftER more recent cafe of thtf 
fame kind has been' communicated t'd? 
tnt by a 'gentfem^ri, oh wKoni I can' 

■ s 



'A'fervant maid in the Hay Market ^ 
abolit twenty-five .years of age, of a very 
robiift habit, took three tea-(poonfuls of 
oil of vitriol, in half a tea-cup* of water, 
as a remedy for a cold. In half an hour, 
or lefs, a great difficulty oF refpiration 
came on, that threatened immediate fuf- 
focation \ and (he could not be perfuaded 
to attempt to fwallow a drop of any li- 

H 4 quor 

Mor^^batCTcr, but was tmiBcsd wIicd- 
^rriti/pri^jiamcd. Hei: pulib «ns bard 
and full, and (he was all over extremely 
hof^.^. Sift. WiSjCurcd by ixmiow bkcd-» 
Jv^^p dyfters^ and oSy .i^edidiie^ irben 
^ i9fa& fapfM^ o^^fikii^ tbcrOi 

••■':-. ■ ^- •-'/. ^ 

• I 

,. JN. tbis^nib, as in^^the -Camae-Afad- 
. 1^, ^. (irgaps, Cff . d<^utitkm feem to 
have been excoriated and ibre, £> as .to 
be io paio upon being moved to fwallow 
9 fiui4> j^.afoaa^wbat.difierent. motion 
of thefe is required in or(]er to fwaUow 

a Hgttic)^ frpni M^hat is aecci3*^ty ^ the 
taking a. fblid* This af^pears frtttBijcafes 
j^^^t xnufi have occurred to cv^ery pra^i- 

-i}f9P^f'}r^f thercj is> not unfjrequent/dif- 
jiy^^^r 9f the O^foph^^us^ .^vhioh iodlices 
^n .ipabjjity to fwaUpvv folios fometirpes, 
. and , fometimes JiquidSf bu( feldoiB bptb, 

;4" ^^5 ^^.; A*g^' -and.T^en.ihe.the par 
jpient (Jic^ fftniifhed. . 

; *« II i'b 

..[TiiE., vicinity, ofj, file O^ophagus \o the 
iij^cra ArUrta, will re^4Uy acgovini ibf 


> ' <» M 

CAN I MIS ^Ma'D^I^ESS. ioj 

^ fuddm ienfiKioa of {tiffb^ l&e 

that ^which happens in Omine Madnels. 


. I Mt7&T. not quit this {objeft without 
cemarking> relative to the fwelling bf 
the ftomach fboo dfter riolent efForts to 
4nnk> that many liquors excite a confi- 
deriable efFeryeicence and heat upon being 
mixed with water, during which a large 
quantity of ait is generated, or nltber the 
air is let looie from its confinement in 
the poises of the fluids thus united. 

Now I think it very pofiible, dut die 
diilempered tnte m2^ hare cootraded 
fuch qualities, as tnsj ibit it ta eSEcr-- 
vefce upon coming into axiuSt vridk 
water/ or any other liqtior^ yfAkk taof 
be accompanied tridi die fenr ^pMff:k^ 
tion of air, and tbe ISme b»e. Am: i 
ioy may not die p wfert^ iCTft ^ ^tfv^, 
would happen ^^y^tM^ xeim-^ <<^^v/^ 
fbmc degree^ iSa^ im^ ^A^ ^^ i^ #^ i^c 
actually happM > )iiit ii^^U tw^ «4Mpm^' 
9s a very sauiiKnHi vfctr^ i^M4^ k-^^m^. v 

citt tbridra of it when abfetit^nrift csrertf 
theifiitieicmetic pcwery:9S.if it was^adiial*- 
lyfwallowed ? The whole frame, there-* 
fint^riies) as it wet^, dgainftk, and pro- 
hilMlt^itiraAiihfion^ into 'the part^ whet^ 
k ^W6uld mod certsirtfy ptoivt^'^ titbm^^ 
ffClA^{)£^i>, not wkhout imminent dan> 
g!Wi«i!f immediate Motion. > 

'•!» tll« third ftag^ alJ the fyrtfptom^* 
afrt Wfltirtwally aggravated j the 'tbngue, 
befidesK ' beeonleS cirtl^emcly rdi%fr, land 
hangs out of the mouth, which remains 
it4A&' open 5 the vdice is roiigft '&nd 
HAlrlfcr «he thirft iinmenfe ; the fight 
oifciftech^'of any fluid kiduces dirfeift fory> 
tnikH particttkrly any attempt to^ fwallow^ 
i«>^AI^ge quantity of foam is coUefted 
irf'WW' mouth, which the mifefable pa- 
tiftri*'^cannfee forbear to fpit out tipow 
thMfe' thiit approach him; th^re is an 
Uiire'ftrainable propcnfity to bite^ 'every 
tJAflg' about him; he grins like a dbg; 
tha pulfe and- re(J)iratiGn become defiei-- 
ent ; cold fweats, and the highefl degree 
1. : V « of 


of rage come on, whilft he wonderfully 
retains hta fen(est.inic^nui$ tol>^a&aid 
of injuring die attendant? ; and l^boati 
the. fbiirth day from the firft i]bage^,hc^ 
di^s;iQ^ ixmwl^ns,. and with. <a;tieaM|^ 
diffieidty of breathiijgw .- 

I MUST here^priz^ the readf^Ts ^tbat: 
thia laft feries of fymptoms I relate upoft 
the j^uthority of B^erbaa^ej and the ai|- 
thi^sdrfrona whop^ hq has cqlled^ed theiOiir 
For I Mvft nqvep feej^ ^em myfcljf ift, 
^ny dogree equal to ^rhat is» her^ cepcefir 
^tedj, ^l I. have attended haviqgb^c^ 
cursed; ift: the firft ftage,. or begmn^ng.gfi 
the fecond : and no one I have cqayei^iird 
with has defcribcd the fymptoms in this 
mftrfi^er upon thei« jowa knowledge. 
Andk to ppaCeis the trutib, I am. a Mtt^pi 
appj?eli^fi(Ve, |hat thQ appearances may 
h^ve bec»iexagg^fiated by an imaginatipii 
pug.'udiced by whft: the earlieft, as well 
as. lateXf authors have wrote^ and terrified 
at the uneooamon^neis of the qaic* , 

• « Am- 


^•''^BV^dletn&ft audientio^^torcounts I can 

ftatiiMTI* utidb^ the infiuonoei o£ilhiiitiif^ 
^iH-lb«ya«^ e:stremel3^ reaiboabk^tiiK 
*grVdls/bttt' often fei^od Avithfpafdayimfc- 
dP'tremblihgs, widi convulfioHs^^^indidif*- 
15euIt!;^^€dF1)i'eathirtgi' Whidi; becotoei mocfe 
l^qiieift*, and ittoM feycre,rtiHvtb« piK 
tient dies fufFocatcd' cither ^by-»i«i»opprt^ 
lion about the Proecordia, or fore throat, 
dh%t>A. Me^ri *^hilc, I cannot leara, 
^^^^' imitate- thc'daionr of,a ^Qg, 
i^^ti&^ri^^ or barking,. mcAie 

tHaft * per&itf who dies of a common' 

' ^^^ THii ' fyhi^6m* iif tending? vtbfe i thirt!^ 
ftij^, I ddhfidfer tortl^ as thoTchdE^tke fe- 
6dnd'a]^gi-aVkted t except as the bloodiis 

'iif6# ^'gteatlf -altered In i iits^v^B^daraoce 
ifroifr ^hat it fe'iri^ts^rnatufaliftater ^aftd 

^ what^ Wis a- feW days 'before^ Tiwis cir- 
biirhftaiice tioay^fdduce ibnxe il^rt^^ 

^cotTttnd^ t6^^ihis aflid alllihfbaiuxiatiQiK. 


It*' is rcmaiikable>.tliat 2itth%sr,tkxys[th^ 
blood appears fomctimes very £27 ? &|g4 
thicks and Jbrnetimes^x a llttile afterk^i^ 
dtiTohedrAnd iiuid^ .as->n6t to con^tcUf^ pf 
coagulate like other^ bloody > wbeii . ^^lal^i 
from the vein, and. expofed to th9 ;^ir« 
But in^this there is apt^iDgiingul^if^ 
the very iame haif^aa ia n^ny othM i^ 
flainmatc^ diftempetiSiA' V .' r ,,„ .^^,v 

• ■ ■' '..V;: :;j* :.:■ .r. <u^\\ 

^ I SHALL avail,n^yfelf of .bat q^ptrjf^^QS^ 
Itrgunaent to; illaftratie th« rprobal^Ui^ ^ 
the Ca^Qine V<6nom being (received :;mi4 ^9f~ 
tered in the membrguie whH:h qpnf^ff^ 
the fat, or rather in the fat itfelf^^ ,1^^^ 
this I draw from the method of cure : 
for thati very medicine which cur?€|f the 
venereal: difeafe, and: many pthef dMjbi!-* 
der8,twhdfe refidence is iort^ fat^if ,sli^ 
fbund'-^flfeiftiml fin prei^nting,. ;gn)d .ffnj^ 
airings ih* Ganine j Madnef^, At; ] kaii ^ m 
the fktHk, or perbapjb the.' f^ond ^g^^ji.^f 
mea» MeKury, for* l}^ie®«'ecy oi *ff\ii^h 

in Ganiwer.'Madneife Ijsflatter myk\i I 


tit) A l?Rfe^A^TISE iOfl* 3 

fhall produce fatisfadory evidence, in the 
fdUowihg detail \)f 'experithcfils^; \: ; ^ 

» ■ I V f 

i • ' * » " 

•>^ I'MLALL begin. with diolc !pTintdi:io 
Aa Pbilofopbical ^ranfoBtdm^ iiotd^ tAj 

i> -;ti t 

1 • !• • » . . . 

ciB Mr; J?*4y^ <s>f Hints j a gcndwnfati; 
who was very curious ill fo^ hound^l 
He complained that he was afraid of a 
teSdhdft atfiongft his hounds j fdf that 
lAfoitiing one had run mad in the'kennd'^ 
ah^ he was apprehenfive, that rtioft of 
tibe' reft were bit by him. I took thig 
opjfortunity of telling him, that I bad 
long believed Mercury would, if triedi 
prove the beft remedy againft tbid 
\tiiiGcLOTi I and that if the idea I* had 
formed of this poifoil wa^f jtift> Iwas 
pfetty fure the medicine wouH arifwer; 
liotwithftanding the difficult there is of 
^eterntining the cfFeds of a m^dkinie^ 
a fti^ i and that it was at kaft worth 
while to try, '^ ' -' " ^- ^ ^ ^^ 


C Am N E M A D,K'E S^S. tu 

> ■ . f ■ t ...'', 1 1 •. «>4 -« 

, J ; , ; • 1 . • . .■ ■ . , , - • ' 1 / * . • > I «••■■. 4 

Mr. F/o^r neglQ,<3:cd thistadvioj/tilLihe 
Febjruary jfoUowiog.* Mean tunc:fae tried 
the fliedii(;inp i», 5^45^, Commonly knQwa 
by th? ijjimft of (Jbc Pewter Medkhtei $y^ 
alfo eyecy thing elic which was recooa^ 
mended to him by other fportfincn, but 
to no purpofe ; for fome of his hounds 
ran mad almoft wt^ty day after huiUiing. 
Upon this he tools; hi$ bounds to the;, li^di^ 
and had I every one of them dipped j^ 
the ialt >vater ; and ^t hi? retufQ, brougl^; 
his paqk to another , gentleman's kemofiW 
fix miles diftant from his own.. Ba{^ 
jiotwithA^nding .^his pr^cautign, he la^ 
fix or{fe.yen couple of .his dogs in a-fortr 
night's itime. ^ .: 

"J .. . ; • t 

Ab9UT this time, which was .in. -F<- 
bruary^ I waited on him at .bi^ VV^yf 
habitation^ and found him in that 
diflrefs not uni|fi)al to fportfinen uppfi 
thefe occafions* I afked him. if. h? b^ 
tried the experiment I had r^pmmen^cd* 
He iaid he had not ; but that two of his 


1 14 A 'rk-fe Alii s fi^ ofr 

hounds were then inad» and he woulcl 
that night do it. He ihewed me tlie 
dogs, and they were as far gone as I ever 
faaw&enany^ They refttfed food of tU 
ibrts^ particularly fluids, Havered much^ 
and had all the fymptoms of an Hydros 
pb^m to a great degree^ 

. I 

He fent immediately to Litchfield for 
all the TLurpeth Mnera/he cfooild^ i and 
that night gave twelve gi*ains a-]:^^e to 
the two dogs, which vonaited and pureed 
them gently. Twenty-four hours after 
thi^ he gave to each twenty-four grains^ 
and after the fame interval he gave forty-- 

eight to each. The dog3 fallvatcd ccm-» 
fiderably, and foon after lapped wanii 
milk. At the end of twenty-four hours 
more, he repeated to one dog twenty^four 
grains mow, and omitted it to the other: 
The dog that took this laft dofe lay upon 
the ground, falivated extremely, was irt ' 
great agonies, and had all the fymptoms 
of a falivatioa raifed too quick, but got 


elhchrciaplfidaaiidiid. ^^ '■*' 3!^^'-" '-■* 

levisa ^graiiU of^itlie ^Ufpetl^ 0jr'^ftticfliirfE^^' 
^ple^.^^fecoiid twiel^i at iWeky-fb^^ 
{ipurs diftance, which^aier liepdittd 'c\teiy - 
other day for fome little time. The 
If^q^d.was fi^catqi at ithe «wo til^thii^^ 
fuqecediog fulls and changds^of^^e^tkdtiiiJ ^ 
From thM time he ioft ' fit)t . ^fei^^t ' ' ^ 
hpto4 j^ ,aiid tM^h/ &veral Jb^v^ &nt6r '^ 
'b^e^ttit %< %^9^ 4^r the T^i^ h»6 ^' 
alii^^^ |||'ev6tfted vftfyy /ill «}nfdqiimipeji < ' • ' 

I f n4 l»J!* ^fti^^f^ h^Q fried i the feft»^ 
jfeipg fioc#viVf«n |kii»ujtittidb« of -46gt^* -^ 
i»0^ $1 lugsr 2}fpyer i^^ed tn ouiy oite^ |(kir iii<^ 
J|%»C<tt ihcmgh fl^SibM a^:th€f4Mfl^^fl(»^'* 
and by the fanw dogsi hare ^tOft^miaJj ' 
after moft oAer methods haifc:.:lic^ ^ 

As^. £(> itb^ ..experimi^ttS' made ti^o6^'^ 
lliiailkiiid# die j6rft was upon a girl about 

I fourteen 


fourteen years old. The calf of her leg 
was fo torn by a mad dog, that the fiir- 
geon was obliged to ufe means to prevent 
a' mortification from the wound. She was 
vomited by the T^urpeth. Three diys 
before the next change of the moon, the 
vomit, was repeated, and again the very 
day of its change. The fame metfibd 
'\vas piirfued the next full "m'odn. * 'The 
girl is very well. 

The fecond was a bdy of about 'ten 
years of age. He had foiir holeis in'dne 
of his l6gs, made by a mad dog in -Kfo-- 
vember, 1735. The Turpeth was given as 
'above, and the wounds drefled with di- 
•geftives; arid he continues well. Thefe 
two lived near Burton up6n Tr'ent^ and 
Mr. Towndrow, of that place, was apo- 
thecary. ' : 

The third cafe was that of a ybiing 
man near Tamworthy of about eighteen. 
The bite was upon the hand. A great 
number of dogs were bit at the fame 



timcjinthe towa where he lived. About 
fjx days after the jn[iifchief was done, fe- 
veral dogs that had been wounded ran 
mad ; upon which he applied himfelf 
to Mr.. Wilforix appthecary in ^amworth^ 
to whom I h^d cpmn^unicated the fuc- 
ceis of the Turpelhin this cafe. The 
youpg man was, , at this time, very me- 
lancholy and d.eje(3:e.df had ti:^aioj3, and, 
flept very little for fome nights beforej^ 
though he was not apprehenfive that the 
dog wl>ich bit hind was mad.. - Hq had a 
4ry fcab upon his hand. He was, upon 
^applying tp. Mr. IVilfon, yomitjed with 
two ounces of Antimonial Wine. 

The .next thing he toolf: was njade 
according to the following prefcriptions. 

Take of ^urpeth Mineral twelve 
grains. Lapis Contrayervce a dram, Venice 
Preachy a fufficient quantity to make 
three bolufles, of which one was taken 
every night, with a julap made of rue 
water, four ounces ; treacle water, two 

I 2 ounces I 


ounces ; compound fyrup of plony, ait 
ounce and a hdlf ^ tifafilufe of Caftftr, two- 

* Upon takings thefe he fwtaf Ve 
rilUth, and had two loofe ftools ev 
day aftdf diem. His tremors went dffj: 
afid he ftept b«!tef . After this he wcht 
info the cold* bath, artd continued pcr-^ 
feftly welL 


" But what is remarkable in this eafe- 
IS, that the wound fan a thick digeft^d 
matter after this method, iand threw c^ 
the fcab, after which it healed of ilfelf. " 

As thefe fadts are of too great impor- 
tance to be ^eft ffanding entirely upon. 
my own credit, it may not be improper 
to give copies of the following letters, 
the originals of which how lie befbffe 

' • ■ ■ - r 


•. * 

, Hints t Smdi^> m^^ M^ * Ss ^ 7 3 ^* 

Pear Sir, 

J' AM iprry yj^u ^ad not t% aqpounl: | 
. pronuTed jTQU iCop^ef , whic^ jyas enr 
tirely owing t^.a^iulltitude jqf.q^pmy^ 
and not out of any difreipeijt The 
quantity I gave che ho^nd tfeat was mad^ 
and recovered, was firft twelve grains of 
the Turpeth Mineral^ refting twenty-four 
hours. The fecond dofe was twenty- 
four grains ; the third dofe, forty-eight 
grains, repeated at the fame diftance of 
time as before. 

The dog that died, was loft, I appre* 
hend, for want of* the fame quantity 
that was given to that which recovered, 
having only the quantity of twelve grains 
for the firft dofe, twenty-four for the j^^ 
cond, and twenty-four for the third, all 
at the diftance of twenty-four hours 
from each other. 

I X The 


The dogs that were not aftually mad, 
had firfl feven grains ; for the fecond dofe 
twelve ; and a repetition of twelve given 
€very other day; and the fame quantity 
was given at the two or three fucceeding 
fulls and changes of the moon. 

Jam, Dear Sir ^ 


Your mojl humble Servant ^ 

J. FloyeR. 

Nofe, The dogs Mr. Floyer mentions 
were large fox-hounds. 

iV. JS. The account of the quantities 
of the Turpeth given the dogs that were 
mad, as related in the Fhilojophical Tran^ 
JaBions, differ from thofe mentioned in 
Mr. Floyer. s letter. I remember I took 
the' account from him a few days after 
the medicine had been given the dogs ; 
but as Mr. Floyer is poiitive as to the 
quantities, probably I made feme miftake. 



Burton^ May 10, 1735. 


IH A V E only two experiments to give 
you of the T^urpetb Mineral on hu- 
man bodies. The firft was on a girl, a- 
bout two years ago, aged about thirteen 
or fourteen years. I gave the dole im- 
mediately, which vomited five or fix 
times, and gave a few gentle ftools. 
Afterwards, at three days before the next 
change of the moon, I repeated the fame 
medicine, and likewife gave another dofe 
upon the very day of the moon's change 
ing. I obferved the fame method with 
her at the next full moon. 

The other was a boy about ten years 
old laft November^ who had four holes 
bit in the calf of one of his legs. I ob- 
ferved the fame method with him, but 
was obliged to drefs the wound with di- 
geftives, laying on a cataplafm of Mithri'- 
date upon it. ' - 

I 4 I 

Y^o " A' ^klBAf I-gfe 6]^ 

- » . ♦ ' 

y ' 

I iiAVB given the fame medicine to 
^ thirty dogs at leaft, none of which ran 
-Hmad, when other dogs, bit at the iame 
^ titaie, died. This is dl 1 have tlnw to 
^ t^rite at prcfent, being in a gredt feiirry* 

/ am youf moji obedient 

Humble Servant y 


< . • 


i^ yT Y Mafter being oWiged to go from 
xVi home, ordered me to give you an 
account of the people to whom he hath 
given the Turpeth^ Mmeral. One of 
them was Anne Bagnelh of Branjloni 
the other was a boy of John Co^vpcry of 
StepenhiU in the county of. De?*fiy ; and 
they remain quite free from the leaft. 
ly mptoms of a Mania. 

He never gave it to any other animals 
but dogs. We have daily inftances of 


the good fuccefs this operation hath with 
them. There Were ftveral which were 
bit the other day. Thofe which \te give 
the tftedicine to, ftand feccms^ uA i^e 
red are gone: quite m^. H^ &nt U.ito 
a perfi^fiL who had two horfes bit^. imt 
they finding no wound, did not gore k, 

If you pkafe, my maftet, perhaps^ 
will give you a more intelligibie 'accouot 
the next poil. I beg le^e is> (Klblbt^ 


s I r: 

Tour moji ^beJknt 
"' BuMhk Sert^nf, 

W. Cotton. 

Burton, May ij, 1735;' 


• • . * 

■ « 


Burtorif May 21 ^ ^735- 

I Was prevented from anfwering your 
. laft letter by a call out of town, fa 
•gave directions to fV^ Cotton to inform you 
of the names of the perfons upon whom 
the experiments were made, and the pla- 
ces of their abode. I cannot recolle£t, 
that' I ever gave the Turpefh to any qua- 
drupeds but dogs. A perfon once ap- 
plied 'to me about a horfe, but I find 
the medicine was not given. We have 
had lately fome dogs bit : I heard of nine> 
three of which were treated after the 
method mentioned in my laft, all of which 
remain well. Three of t]ie other dogs ran 
away mad laft week. I have never yet 
had an opportunity of trying the Turpeth 
upon any thing which had tire fymptoms 
of madnefs. When one of that kind of- 
fers, I fhall communicate the effedl of it 
in that cafe. 

» 'I amy Sir, 

« • 

Tour mojl obedient humble Servant ^ 




TH E youth that was bit was about 
eighteen years of age, it was thic 
Hxth day before he came to me. He tuad 
little fleep from the time he was bit, WJ» 
very low-fpirited, attended with tremors. 
I immediately gave him as follows. 

R Vin. BenediB. ^ii. 

R Turpetb Mineral Gr. xii. Lap. C(m>^ 
trayerv. ^i. Tier. Androm. Q^. F. 
Bol. No- 3. 

R Aq. Ruti^ gvi. Ther. jii. Elix. Campb. 
Gut. 50. Syr. Paon. C. Jifs. Tmff. 
Cajior ^n. M. 

I afterwards cold bathed him for five 
mornings. The bite was on the back of 
his hand ; it was, when he came to me, 
a dry fcab. The fourth day after bath- 
ing, the wound run a thick digefted mat- 
ter, which flung off the fcab, like au 



gj^ A T A £ A T I S E QN 3 

The youth was a fervant toJ^Ir^ f^^ 
ffi^fi^{ 4^ry., Th? cure has been ouipb 
^^K;e^^ abroad. -Two of my buiiwie 
hf^ve been very bqiy to know whjit 2 

1 amy Sir, 

Tour mojl ahedient Servant , 

R. Wilson. 


....... f 

/* P. S. The voniii: broiight. up a 

=/ large quantity of flimy matter } it alfb 

gave three loofe ilools. He fweat 

** much that night. He took every 

*^ night afterwards one of the bolufles, 

<« and four fpoonfuls of the julap, which 

** made him fweat very much. His fpi- 

^* rits were much better; he l^ad two 

'* loofe ftools every day. Three days 

*< after he had finiflied the boluffes, he 

^' began to bathe^ which he thought 

« gave him frefl^ life. He took, as long 


C A'N I N -E ' ]Vl A § i^l S^. H§' 

** as the julep held out, four ipoonfuls 
** at bed-time. He fkpt ihtick 'better 
**thanufual. I ordeired hioi W atoW 
^ from fait meat and fpirftoiDus^ li^iioWi 
^ but to Kve on puddings «lnd -fueh likB 
** diet for a month. He is perf<g<aly re-* 
^ covered, and continues very well* 

- ♦v The misfortune happehed in De-' 
*' cemier" 

I HAVE been concerned myfelf in ^ 
great many cafes, which abundantly con- 
firm the good efFedts of Mercury, both 
aS a prefervative, arid a cure; amongfi 
^hich the three following feeni very fc- 


f . ■ 

In 1739^ a neighbour's dog carne into^ 


my houfe, and very much worried z 
middle-fized fpaniel bitch, malting many 
wounds in feveral parts of her. Imme* 
diwely before and after he worried feveral 
dther dogs in the neighbourhood. 




•; Ashe was a dog of value, his mafter'a 
^rvants caught him, and tied him up*, 
■yhe next morning, upon a full: conyic-r: 
tion of his being mad, he was j^9tw 
My fpaniel had immediately all heo 
wounds . dreff^d with a . Mercurial pint** 
ment ; and took every day, for a fort- 
night, jTwr^/y^ Mineral in fmall dofes, 
by way of alterative. After that, I^ had 
her dipped every day over head in cold 
jyater^' The bitch lived many years af- 
ter, and at laft died of an accident. 
■ J • - • . • , . 

As fbme other dogs were much va- 
lued, the Tin medicine was given them^ 
and fome other things, commonly efteem- 
cd fpecifics ; but in about a fortnight, 
,they moll pf them ran mad, and the reft 
^yrere deflroyed to prevent farther mif- 

The other cafe is that of a young la- 
dy, about five years old. Her father had 
an Iri/h wolf-dog, of uncommon fize, 


C ^NI N E M A t)'NE SB. titj 

which, about two years ago, runnings 
mad, met his daughter in a p^flage^*^ 
threw faer upon her face, and ftood over, 
her, endeavouring to worry her, till the 
fervants came and releafed her.j V'^ry 
fortunately he had a garland ftftened 
to a collar about his neck, othdrwife 
probably he had Jcilled hen. " .} ; - 

A garland is a thing 'well known to 
the fportfmen, confifting of two hoopte 
crofling each other, and which . hanging 
before a dog's fore legs, prevents his 
running after fheep, or being otherwife 
mifchievous. » 

The dog was immediately tied up ia 
a ftablei and a meflenger difpatched to 
me. As I was twelve miles from the 
gentleman's houfe, it was fix or eight 
hours before I could come; When I 
arrived, I found the dog raging, and he 
was immediately after fhot, for I wa$ 
not then at leifure to try experiments 
upon an animal capable of fo much mif- 




chief. I was informed, that h?r cap 
had been pulkd o£F, her hair very muoli 
difcM'dercd, >aad that the dog had^ hw 
^bole head fever^^ times in' his iiioudi;^ 
I diredted for her Turpetb Minend vot 
fmall quantities, loaded with Camphirej 
which difordered i her fo mmrh^ that ii 
was obliged, . inAead of it^ . to igive pills 
made with crude Mercury^ divided ^th 
turpentine, and FU. Ruff. After this 
fhe made) u& of Htx^ cold hath for foenb 
tirne^ and continues perfectly welL; ^ 

Had there not been a great number 
of other cafes to eftablifh the reputation 
of Mercury^ as a prefervation againft the. 
Hydrophobia^ I (hauld not hayc given 
this inftance al5ne, becaufe wc were not 
certain that the lady was bit, ^ though 
there w«re fevcral fcratches on the back < 
part of her head, which alarmed us 
much ; but it is poflible they might be 
made by the comb. 


C 41 K I|^ E - M A^IWIf B $ S) jS§ i 

• ' . . J 

.\ At the fame timcKa boy ibout fou*-^^^ 
Xeen» was brought to me^ wiiofe arm had ^i 
)9,e,e4 much wounded and torn by a mad 
jdog> aboujfj ten days before. )i .y;ir> :^ i 

, :\Another l)oy, wjio had -Jbcoti bit by v 
the fame.^dog iqt the head/ died ^niad in ' 
a very few days. . 

r , - . ' ■ • ■ \ • ' y I . ' • ; ) i • * 

^ ; This boy's wounds Iddked* very livid. ' 
He took the Turpeth in large quantities, 
hi§ wounds healed, and he continued 

' r ' 

'. Some time in' February or March, 
1738, I received from Mr J^bn Douglas, 
a furgeon in LadrJLaney a letter, with a 
printed half fheet of paper ioclofedinit, 
which jDo w li?s before me f and of which 
.here follows an exadt copy. : 


1 3© A 'f'R <E A T IS E' 


'!. ■ • 

i ' .. 

-/f fure Metjbod of pre^^ingi and^ie 

'^ 'moji pribdbk Wny tfcuringi tbe^Wj^ 

* drophobffl?, ii. c. the Dread (f Wmtiry 

^ after the bite of a MadD^g j a Diii* 

^ cafe hitherto found incurable 6y the 

. ^ PraB&lioHers ofuU Nations *: By J%hn 

* A S foon as may be, after a per£>d 
' -^-3L is bit, bleed in the neck or arm f 
^« then kt a drachm (Mdr6 or leffil>'^*. 
'^ cording to the difcnetion of the furgeM) 

* of the Unguentiim BenediStum (R AfjgMl 

* vini purifs. axiing. human, porcin. ana Vbi 
^'Terebt. 'ven. clar. §ii. M* S. A.) - be 

* rubbed into the wounds and parts >a«t- 
^ jfecent, Theh give one drtt€hm> nioit 
^ or left, of th^ following powder *> lA 
'^ a gkfe of \*ine an d water, watery or 

* cow's milk-WArm* '{^' Herbs Licikfh. 

* cinerei terrejiris fubtilts. puh. ^ifs. piper. 

* ^W' y^^^/z^J. pulv. ^. M.) Repeat the 
- ^ ^ un(5kion 

* Vid. Pulv. Antylin Dampr. Philof. Tranf. No, zij. 



^urid:ion ^very evening, and the powder 
^i^cryrmomiBg lifting, for three weeksi 
•f;ior A month, inuteriiritting two or three 
^iiaya^ when-. <die mouth begias. to be 
^** (Sue, . to . ^eycnt a fali vation . Then 
rfrjjingc off. the Marcurjy f.a.\\tt the pa- 

* cleat recruit for three or four: weeks, 
f an4 afterwards go into the; cold bath, 

* or the coldeft water in the neigbbour- 
f.jgkood, as ufoal, if his furgeon thinks^iit. 

}:^\f ..'•■■. ■ 

: ,,tWHfiN thr<Dugh neg^e<3:, (i> e. when 
:f I lihcy ; did not imagine the dog. .was mad 

* which bit them) or after they have 

* been amufed by going to the fea, eat- 
•^ iog part of the dog's liver, taking many 
Vincoaifiderate jumbles of antidotes ^ &€. 

. ?:-dbe harbingers of -an Hydrophobia ap- 
^S . pfear {viz, tuopi flin e&, dejeiSedn efs^ 
■fi\ W9l2t of fleep, or fleep interrupted with 
:* horrible dreams, unufual pconenefs to 
Mtiiger, tingling numbed pains, and 
^^j^elling about the cicatrices of the 
^ wounds, great inward heat and thirft, 

* IremorS; corivulfions, delirium, ereat 

K 2 . « pains 


* againft the fting of the fcorplon, the 

* bite of the viper, rattle-fnake, anck all; 
^ the fcrpents in the Eaji or W^ 
« Indies^ &c. ,f. ^ 

1 - ' ' 

* I SHALL: be exceedingly obliged to 

* any gentleman, who will communieite 

* a fliort account of all thofe they hwc 

* either known, or heard from gobd 

* hands^ were bit, within twenty yecErs 

* paft, viz. when bit, what fymptdftis' 

* appeared, from firft to laft ; what t*tts 
« done for them, and the fucceft, good' 

* or bad, with any other material cir* 
< cumftince, as alfo their fiiccefs with 

* this New method. 

* Feif. 26, 1738. 

Non fiimum ex fulgorcy fed ex fumo dare 

Cogito - — -- 


Given gratis in Lad-lane^ near Guild-Hall. 

CANINE-iMADIffES.'S. 13-^ 

< I HAVB troubled the reader with Mr. 
Douglas's paper at^ length, ia order to 
fecure to myfelf the honour, however 
trifling, of having been the firft that ap- 
plied -Mifr^^^/y internally to .the cure of 
the Canine Madncfs, which I find has 
been difpjuted with me, in favour of Mr. 
jfohi Douglas. But as this appears to be 
^e firA thing he ever publiihed on this, 
fubjeft, ^nd :a$ b^ quotes my Memorial, 
printed in the Philofophical TranfaBions^ 
'tis very certain, that I wrote upon this 
fobje(5l before him. Whether he ever 
publiflied any thing farther afterwards, 
I cannot learn ; but I believe he did not ; 
' for I remember, that, not long before his 
deceafe, he defired I would give him 
fome cafes; and I think, if he had 
printed them, he would have fent me 
a book, as he did upon other occafions. 

It may be obferved, that Mr. Douglas 
quotes Deff'cidtysfur la Rage, a book wrote 
by a phyfician of Bourdeaux. As I had 

K 4 never 

136 AjTREATlS/B ON) • 

never either feen or heard of this au- 
ihovj I pptitioDied him. to. fend it me, 
which, he very, obligingly ddd . foon after. 
And I was, ouicly plcafed to find the effi- 
cacy .o£ Mercury confirmed by fomc ex- 
traordinary cafes there related. . » 

,,As JDeJauk*& theory feems but iudifJc- 
reut, I (hall confine niyielf in my quota- 
tions from him, entirely to his practice, 
as much more worthy of notice. 

* The remedy, fays he, which I have 

* tried with conftant . fuccefs, and which 

* I propofe to prevent and cure the Hy-- 
\drophobia, is the ointment made of one 
f third part of Mercury revived from Cin-' 
f . nabar^ one third part of human fat, and 

* as much of hog's lard. . 

.. * This ointment fhould be rubbed 

* upon the wound, and round about, one 
^ or two. drachms at a time, by intervals, 

* pr fucccffively, 

I think 

eA N I N E ■■ M A N E -S S. ty^ 

. . . • : • ' ■ / '. . . ' .. I ' 

• I 

^ I think I am the firft Who made this 

* trial, and have no reafon to repent it, 

* fince all thofe who have followed this 

* procefs have been preferved from the 

^ Hydrophobia^' 

; ^ When a perfbn comes to me im- 

* mediately after the bite of a mad crca- 
^ ture, I fend him to bathe in the feat;* 

* although I have no dependanc6 upon 
« its efficacy, on account of the fad ex- 

* amples we have feen of it this year. 
' Neverthelcfs, as it is authorifed by the 

* opinion of the public, to omit it would 
^ be flying in the face of a general pre- 

* judicc, and it is at leaft: of fome ad- 
^ vantage, fo fair as it calms a little the 

* patient's mind, who meafures his con- 
< fidence by the great number of medi- 

* cines he ufes, to fecure himfelf; and 

* the bath abates, in fome degree, the 
^ great fear which fatigues him night 

* and day, I have obferved, that their 

* ap- 

X%S .A T'H'IE/A t IS E : N > 

* apprehenfion increafes as they come 

* nearer the fortieth day. . 

*t ■> 

/ni^.SECONDLY, immediately after his re- 
fittirn».. I make him take Pa/marhis's 
^powder, to which I zdd the. CaraU 
' /ma, an excellent vermifuge. We 
*- flibuid be guilty of ingratitude to our 
fc prcdcceflbf s in pltyfic, if we ni^leiSted 

* thofc remedies which they have tranf- 
« piitted to, pofterity. And if the ideas 
« which I propofc are juft and true, we 

* are^ much obliged to the ancients for 

* them^ fince they are only confequcnces 
1 drawn from their obfervations^ and the. 
f iuccefs of their medicines 5 and this 
\ which I prqpofe has occurred to me 
^ from the analogy of their precepts and 

* do<3:rine. 

■ - ' - • ■ 
. * I; therefore order one drachm oiPal- 

^ marius's powder, in white wine every 

* morning ; and women who cannot bear 

* wine. 

CANINE' ^I»A'til^ESvl *^ 

* wine^ -lake it ih a draught of if^^aipih' 

■ ■ •• ... 

- ' In ^ this method I pcrfevere thirty* 
^- d^ys^- with thofe who have been bit^ilti 
*an uncovered places or have received 
' fome confiderable wound by the bite ; 

* but to; thofe whd have been bit itt a 

* place that whs covered, and had'oisty^ 

* a few holes made with the teeth, I givfc 

* the powder only twenty days^ v mm 

* Thirdly, from the firft day of 

* ufing the powder, I make them rob^ih 
^ one or two drachms of the ointrntot, 
^ upon the wound and adjacent par tv^ind 
^ extend the ointment all over the part 
< that wjis wounded. 

t • • 1 • » 

•^ The friftion is repeated every other 
* day in the beginning; and after the 


* Palmarius's Powder, and what may be expe£ted 
from it, will be feen in the fequel. 

I40 A-TREATI§?35^ ?CW^3 

^'itliid time> cwtry third day; after. tlbe 

* iiztb, every fourth^ till two ^Of: thuse 
' ounces of ointmeDt have been o/ed ; 
« the quaiipty of which ought to be pro- 
\ portioned to the ftteogthj, age, tempe- 
^,nmBtit, ibc, the bitej &c. 

■ '•■ '**■■ 

• BvT when the patient comes to: me 
^•icveral days after the. bite, for fear of 
^ accident, and to prevent the RaiitSj T 

* order him to make the frictions daiiy^ 

* for four or five davs, and increafe the 

* dofe of the powder ; afterwards I leave 

* a day or two between, to avoid the*ia« 
^Kvation which might enfue from ihe 

* daily ufe of the ointment. ' 

* I n AVE often thought, that if the 
' Mercury (hould occafion fome flight fa- 

* livation in this cafe, it could -not but 
•'produce a good effed:; for the poiiorr' 
' of the Rabies flicks to the fathai a5 

* above, and as Mercury naturally tends 

* tdwirds the mouth, as daily experience 
« evinces, is it to be doubted, that the 


C A!^\ N'.fi VM A't) N'E S>6. ^41 

* icivefcign antidote^f fa *rnaf!y' eonti^- 

* dusr j)oifons, • (hould ^hb't deftro/ ^fd *tSaV 

* of the Hydrophobia^? ' ' - • -^ •'(• ^^ 

^ all thofe trifliri^ neinedies he»Js»''^S*^a 

* to, as wearing of amiitets -about ^hi& 

* neck, (3c. provided they do not weaken 

* or deftrdy the yirlue/ofrmy^p^^^ or 
^ ointment. I infinitely approve d^vo- 
^ taohs and vows, aftd^ani' o^-^plinlon^ 
^ trhtt: J his prayers^ fliofc of his ( jfrieiids, 
^ and of devout ' andI^>p(oua peribiais, 'pro-- 
^ cure a happy fucce^' 'to' the rejiiedies : 
^ thefeineans fervc at.leaft to quiet-dae 

* patient's mind^ who -ftanda^ m great 

* need of it. -- . - 

1 r .-■ . : i . . « I . I 

^ Fifthly, I -let him k?ep to fhis 
^ ufual ' « meals, forbidding him * all er-> 

* ceflcs; for experience proves that they 
i^incredfe all the other contagiotus di- 

* ftempef$. ^ > Llct him ;, drink wine with 
i ^oioderationi. which fea& ^virtoQ {4:)f ma- 
-^kirig^eofple bold; and in this^prefent 

* cafe 

^fi^J^ dy^Eiinifhes^ at leaft^ that taiMa 
A.fear>..wbick . torments them mght «id 
* day. I take care that they be nor left 
' alone, and deiire their rekticms and 
*Jxitad$^ to bear' thonr cprnpaoy, ibrbkU 
'^ -diii^* them to tacadon madne& to them> 
« or jnadrpreaturcfif .. ;.. /. 


• ': " ■ . f . 

'.irA«gehtlewomto.]Of this city> {Bmr^ 
^^Jeaiix) i going to^ 'M^doc^ found > upon the 
^/iroada Jittk fl:ray:d6gi which run sEfaout, 
•^ fitting afterwards down ; his tftU^ was 
•; between hi« kgs^- and his tongue hung 
/, dot- ctfhi& mouth.. The dog followed 

* the chariot flie was in, with ipirt of her 

* family.. As foon as he faw fome (hep- 
< hcieds dogs, he purfUed thenii» findtnade 
^thetoji run awavy ialthough much bigger 

* tban<^im£dl£i Moreover^ be fun tato 

* eveiyi.houfc upon the roadp andiet^upon 

* the dog3: ^rong or weak, with a fupe- 
Vffiomy ;x)6 courage, and' ftrcogrfj,. which 

. - J . ^ » 


* pleafcd the hdy^ who thought' {he-hkd 

* been lucky in linding.^igabd hdufo dogt 

* Her cow-herd came down ta Catch 
him, prefenting him a piece of meotiha' 
had left of his breakfaft. The dog rb- 
fufe^ it, but bites hipi in. the-hand. 
He then judged him to be mad, tcld 
his lady of it, an^ wanted to :k^l^^^ial. ^ 

* Sh£,. \vho amoflg many. oth?!:\fine 
f qualifieations is of a humane diipofitiwi> 

* oppofed the cow-herd's ciruelty,j..and 

* ordered him to let the . <log foUq^r htfu 
rThe dog was hardly^ corner iator the 
^ houfe, but he bit one of her childreo i 
*aftd at that inftant herfelf^ alfb> dn.the 
' haad:.ftt)ove the little finger, anjii Md 
*ibfaft,that notwithftainding flifc endea-i^ 

* voured to get lobfe her hand; lifttipg 

* the dog up from the ground, and iha-^ 

* king him .witb^aJl her might ; and al- 

* though I they ftrucfc I^ini witii . great 
^ fttitks» h<^ dkindt quit his hold t^l the 

* whole .part he had fcizcd was tore with 

* * his 


' his teeth > which made a confiderable 
« wound iniier hand* 

^ They found too late that the doa: 
^ was mad^ and then he was killed^ 

« The lady went to the fea, although 
the weather was pretty cold. After 
ihe had bathed ^ ihe eat a pancake^ in 
which they had put calcined oyfter- 
Ihells ; but her mind was not eafy, ter- 
rified by the fatal and frequent exam- 
ples^ which were before her eyes in her 
country, fhe afFefts folitude, her fleep 
is interrupted by terrible dreams, and 
her mind is filled with unufual ideas ; 
and heir fear went fo far, as to think 
herfelf upon the verge of madnefs : 
She often afked for water, to try whe- 
ther (he had any abhorrence to it. 

• * I WAS called to vifit her dt medoc ; 
• altho' it wag feveral days after flic had 

- * • m 

•^ been bit, the wound was not cicatrifed, 
« but appeared of a livid colour. 




^ I BEGAN with chearing up her mind 

* i&jmuch as poffible; I repre&ntcd to 

* her the infaBibility of my method^ -and 

* the certainty of my experiments, and 
^ that they never had been followed' by 
^.ttny bad confcquences. 

t ) 

* I made her take Palmarius's pdw^ 
^ der, and rub the wound, and the hand 
^ every daty with half a difetchm of 
^ ointment. I pcrfuaded her to g6 abroad, 
** to fee company at home and clfewhere, 
f and to go to jthe concert in this city. 
^ By this meaiis {he is perfe<9:ly recovered 
^ of her fright, fecured from the diftem- 

* per; and enjoys a good ftate cdf health. 

» ■ • . • 


- * A mad wolf went and attacked, be- 
^ fore day, two dbgs of one F^ey Dumeniu^ 
^ of Ae 'parifh of ISouffans^ in Medoc^ k 
« tenant to Mr de Latour 'Dmons. He 
i^* L * begins 

^ begins with killing the dog, which was 
?« able rtd make the gi?eateft refiftante; 
^ the :othcr ; was afterwards nioft cnidli^ 
* torn, dnd ahnoft put to dcaih. • 

^ ■ 

V «:THad fccne did not pafs witfamit a 

* great deal of noife on the part of ^t 

* dogs. Pey Dumeniu awakes, opens his 

* door in his fhirt, and runs to help his 

* dogs } the woTJf jumj)s upon him/ ind 
'« bites rlhim in both' his^ hands and hii 

* arm.^ iiis ion, called C^i^u?/, alfo, gets 

* up in his fhirt, and runs to hdp his fa^ 

* ther with a rake in his hand. The 

* wolf lets '• gt) his hold, artd falls upon 
f the fonv whom he bites fevercly in- the 
.*^ arm ; the fether, in his turn, althkmgh 
*. wounded, :: corrtes to fuccour his fon. 

^ The wolf runs away, and meets aneigh- 

* hour who was got up, named , Jean 

* Giiiraud ', the wolf alfo bites him in 
•5^ his. iafm» making three or four cohfider- 
/ able opetjiings, befides feveral little ohes^. 
/* This Igfti' man feized the 'wolf by one 
^of hie Jbioii Iegs,.<Eind niadc him quit 
iff - *'lus 

canin:e madness. 147 

**ius hold. The animal continues his 
< tour^ and meets with a (hepherd of 
^.Monf. Brethonneau, called Criq^ whom 

* he bites. At iaft the wolf was killed.' 

- > ,Here are four men bit by the fame 

* wolf, the fame day, and the/ame hoii^;' 

* tki^y all foUr go to the fea to bathe,* 
^ ishd confie back pretty well aflured of 
<^lheir cure. ' 

^ *^ Some days after, Pey Dutrteniu feels a 

* numb pain about his fears, which grew 
*iiard, and rdfe like embroidery ; he Was 
< very much frighted ; they comfort him, 
^ attributing it to the great cold of the 

* winter of 173 1 . A little while after, 

* however, he Is feized with all the 
i^ifymptoms of madnefs, as well as Criq ; 
-^ they both die mad. 

' r^rDoMESTic examples ftrike and inti- 
^ midate commonly more than ftrange 
:f, ones. Coufiot Dumeniu having feen his 
^ father perifb, expefts the fame fate ; 
i^ L 2 « and 


* arid the rather, fiticc he bfegins to pc^^^ 

* oeive pain in his cicatrices^ and a fwdtt-' 
Ving with hardnefsi Ji^an Gmraiul, Mtf 
^ companion, is in the fame cafe. ' * 

: * Monf. Joutardf merchant of Cq/Ue^ 
\ naUf a very honeft maja^ -and my pfauiU^ 
\ culaf fdeji^ fends thmi to me wilili*^ 
Vcut dt4ay./ I exaa>^n$iij^eir cida^-* 
^ ces, and wondered that the wolf's jiie^tb 

* could have made fuch large wounds 1 
f the parts were hard;%fid felled; and 
^ I doubtdd not bi^t (n^ne^s was ne^f ;fife 
f hand, if .iome remedy was not applied 

* immediately^ the oth* twb unfortu-* 

* nate perforhs having died one or two 
^days befoce* 

I J 

. . * i MADE them' prefently rub in one 

* drachm and a half of mercurial omt^ 

* ment, which I made them extend over 
5' the icicatrlceJ, arid the whole arm. TFhis 
•/ was repedted three days fucceffively. I 
^'..thought the cafe too prefling to fofier 
;^ .any inteivaL ' After the three firft days, 

L. ' *I 


^ I made them rub themfelves evefy 

* other day, and after the fifth frlftlon t 
^kft two days interval 5 however they 

* took every day a drachm and a half of 
^ Pa/manus's powder. \ 


* These two patients were perfecJUy 

» . . • • •■ 

^ cured, and returned to the plough. J 
t had . thq pleafure of feeing, after the 
^. ithird friction, the cicatrices grow fiat 
1 and ibft, the ps^in went off, their G06- 
*jrage rpturned^ and- their iriirids refumed 

* their natural tranquility, in proportioii 
^ as they perceived the accidents difap- 

* peared which had terrified j^em. 

■ * Can you wifh for a more diftiftdl 
^ cafe, to prove the efficacy of Mercury to 

* preferve perfons from Canine Madnefs,' 

* than this, which I have here related.' 
< Four men are bit the fame day, the 
fiame hour, by the fame animal; two of 

* them die of madnefs, the two others 

* perceive the fymptoms which foreboded 

* mjdnefs to the others.; but Mercury fe- 

h 3 * cures 


*. cures them, affifted by Palmarius'a 
f powder. Truly if I had but this ob- 

* fervation only, it would deferve the at- 
^ tention of a practitioner. 


, • • . - ■ • • *' ■• 

* Old Dumeniu.v/zs bit in both his 
f hands, in the arm, aftd thighs; the 

• number of wounds might accelerate his 
f madnefs ; befides, they had been made 
•in parts not cloathed^ he being in his 

♦ fliirt. 


'In the conftcrnatioh the two patients 

* who came to me were in, I omitted 

* nothing to raife their courage ; I even 

* gave them the medicines gratis, as well 

* as my advice, to fhew them, by not be- 

* ing mercenary, how confident I was of 

* fuccefs. 


C AN 1 N E I M A D N E as. 1,5 1 

* ». - • 

REMARK III. - : - ' 

^ The fwellingj^ pain, and "hardiiefs x>f 

* the cicatrices foretold fome days before' 
^ that madnefs wasxoming on ^ as in the' 
*. yenereal difeafe, buboes, for example, 

* and cicatrices which grdw^ haird and' 

* fwell, are manifeft figns of the pox. 

v.'', But this is hot the only iftftance 
' where it fymbolifea with the Hydropbo^ 

* bia. The venereal diforder is contraft- 

* ed by the intromiflion of the poifon 

* from one body into the other ; fo is the 

* Hydrophobia. The venereal virus is 
^ foxne time before any of its f5miptoms 

* appear 5 the fame fcene paffes in the 

* Rabies. Authors obferve, that the ve- 

* nereal diftemper has fometimes lain 

* many years dormant, before it. appeared; 

* the like has been obferved io the Rabies. 

* Every one who expofes himfelf to catch.. 

* the infeftion from women, does not 

* take it ; fo likewife, not all thofe who. 

L 4 * are 

1:52 .A .TREATISE ON. J 

« are bit by mad dogs, contradl the Ify-* 

* dropbobiaf. 

^ All theiib ftrokes of refeinblance be- 
' tween the venei'eal difordcr and the Ify^ 
' dropboiaa^ . :are as many inconteftible 
^ proofs of the ufefulnef$ and efficacy of 

* Mercury in the Rabies/ 

' • V 

So far Dejfault. I confefs I never had 
made ufe of Mercurial imfdon in die 
cure of Canine Madnefs, till I faw this- 
author'^ book. But I think I may fairly 
claim the priority of applying Mercury, 

Dessault tells us, that when Pey 
Dumeniu was terrified upon the firft fymp- 
toms of the diftemper, they comfort him 
by afcribing his diforder to the coldnefs 
of the winter of 1731, whence it ihould 
feem, that this cafe occured in 1742. 
Now it appears in the Fhilofophical "Tranf- 
oBionSy that I recommended Mercury in 
this cafe about Michaelmas, 17JI* and 



that it was tried the February following 
with fuccefs, 

I MvsT not pmit the hiftory, fo far as 
I could inform myfclf, of a medicine^ 
which I hear has been fuccefsfully ufed, 
both as a prefervative from the Hydro-- 
phobia J and cure of it 5 and which feema 
very ftrongly to prove the great efficacy 
of Mercury in this diftemper. 

Sir George Cobb^ a gentleman formerly 
In the Eajl Indies^ brought from Honquiit 
two forts of red powder, which are much 
celebrated in that country, as efiicacipus 
in this diftemper. 

Upon examination, thefe two powders 
proved Native and Factitious Cinnabar, 
and, according to the beft information I 
can get. Lady Frederick brought the fam6 
remedy from the fame place. The pre* 
fcription is as follows. 



V ■ 

Take of Native and FaBitious Gin^ 
naiar, each twenty-four grains; Mu/k 
fixteen grains. Let them be powdered, 
tnd mixed well together.* 

- This powder is to be taken ail at 
cnce in a tea- cup full of arrack, and is 
faid to fecure the patient for thirty days ; 
after which time the dofe is. to be re- 
peated in the fame manner ; but it (hould 
be done as foon as poflible after the bite 
is. i-eccived. 

V- - 

i But if the pati<?nt has any fymptbms 
of the difeafe upon him> the fccond dofe 

/.. . J , ■ > 

• Th^ original rf ceipt was given me by pother 
hand in this form. Take two Candarines of the beft 
Mufk, five Candarines of Native Cinnabar, 'five Can- 
darines of Vermilion. Grind them fine, and mix 
thci5 inaglafs of ftrongarrack or brandy. A.Can- 
darine oi China is the 7 2d part of a French crowii»fp 
that one phyfical ounce is rather more than 76 Can- 
darines. , This I thought proper to infert, tho' not 
cxadllyagretable to Sir George Cobb*s receipt. 


muft be repeated three hours after the 
firft, and this is faid to be fufficient for 
a cure*. 

• Sir George Cobb commumcated. this {9 
Mr. Roberts i an apothecary in PallMall^ 
yi\iQ publifhed the receipt in fome of the 
daily papers ; and I hear Sir Benjamin 
Wrench oE Norwich , xOiZjdib fome expcri-i 
ments with it fuccef^tdly> as well: as 
many others. 

- Faditious Cinnabar is made of three 
parts Mercury to one of Sulphur ; and, 
as I remember, a pound of good Native 
Cinnabar yields near fourteen ounces of 
fluid Mercury ; and therefore it feems, 
that the good effefts of this medicine 
ought to be principally, if not entirely, 
afcribed to Mercury. 

As to the Mufk, it is an animal fub- 
ftance, and confequently of an alcaline 
nature ; and as alcalies have in all ages 



been recommended in this cafe, it fccma 
tQ be at leail not prejudicial. 

« . •• 

The Chinefe are very fond of per- 
fumes, and probably give Mofk to ren- 
der the medicine more agreeable. Bat 
I think it may be. of fbme further uft; 
as it is a great cx)aipofer, and excellent m 
GOJQvuliions. It mayt therefore, mode-* 
rate the lymptoms^ whil/l Mercury per- 
forms the cure, 

Claude du Cbtufel^ a' Jefuit, and apothe- 
cary to the miffion* of Pondicberry, bav-f 
ing fent fome papers to Franccy relating 
to certain experiments he had made withr 
Mercury in the Canine Madnefs, thefe 
were publifhed at Farts j in a pamphlcv 
in 1756, and that year tranflated into> 
EngliJJ^. . As his obfervations are extreme-^ 
ly interefting, and the cafes he relates 
amount to a full proof of the efficacy of 
Mercury in the cure of the. Canine Mad-i 
nefs, I Ihall here add his. teftimony ta 
what has been already advanced. 

' Tho* 


« Though, fays he,' it is but abbuf 
fourteen years that I have been in India, 
I imagine that the dldeft pra<3itloricrs 
of phyfic- ill Europe' have fcarcely had 
{o frequent opportunities of treating per- 
fons bit by mad animals, fuch as dogs. 
Cats, foxes, or by their own fpecies,^ as 
liiyfeJf, Animals, elpecially dogsi Ste 
much more fubjeft t6 madnefs in this 
country, than in France. THe gtfeafc 
heat of the climate may, perhaps, be 
one particular caufc; and theit food 
may likewife contribute to it. They 
get very little food in their mafterS 
houfcs (who are commonly very poor) 
and, for the moft part, feed upon car- 
rion. This corrupted aliment, no 
doubt, predifpofes them to madnefs. 

; In the exercife of that charity in 
^ which I am employed, in giving medi- 
^ cincs to the fick, I have had the morti- 
• fication to fee many die of this mad- 
^ nefs, after having treated them in the 

^ beft 

1^58 A: TREATISE :0N 

« beft manner I could, according to the 
^ common rules, of medicine. Hence I 
f l^ad reafon to be .convinc^d^'tjiat thofe 
^ who Jiad wrote i^n thisi diftenSpcry 

* had not yet difcovered a fpecific for it. 

,.if Ths authors .who have treated on 
fj4Jbi$; diftemp^,, at leaft thgie whom I 
f iiaye^.h^d aq opportunity of perijfing^ 

* have ajl fpoke <>f it in ai^. indetcrmi* 
*,nate.and obicare manner. . I know of 

* BO author, but M, Dejauk^ who dc- 
f. icribes this difeafe conformably- to the 
appearances I have obferved. 

* TjHE rcjoi^edy of M. Deffault is Mer- 
*,cury^. Before Lmade ufe of it I had 
«,fried, in vain cordials, bitters, abfbr^ 
« bcQts, bathing in the fea, and every 
« thing that is prefcribed in medicine for 

* the cure of pgrfons bit by mad animals. 
« At the month's end thefe perfons died 
< with the mpft^eyident fymptom^ pf this 

* madnefs, as a ghaftly and even convul- 
« fed afpcift, and faultering voice ; they 

* fighed 

^ fighcd, and were i»t capafeie of - ex- 

* plaining what they felt 5 they '^Voided 
*'the light, had a dread of water, and 
f fell into convulfiofls when it wi^ of- 

* fered them to drinfc. .r\ 

> ■ • 

* Many of thofe who were undir my 

* care, flattered thehifelves that they had 

* efcaped the fyniptoms < bf tnadncis,'^ and 

* even death itfelf,: by. the ufe of the 

* common remedies, which T gave, when 
^ firft I undertook to treat this 'diforder : 
f but I iim perfua^ed that the ^ animals 

* which bit them were not mad* 

... . . . - ^ . 

**The marks afligned by authbrs to 

* know a mad dog, arc fometimefe v6ry 
^ ^mbigub^is. We cannot always judge 

* by the appearance, whether a dog is 

* mad or r not. In this uncertainty, t 
^ have followed the fafeft and moft ra- 

^* tional method j which is to take for 

^ granted, that all thofe who fay .they 

« have been bit by a rnad animal, 'Have 

* been fo in reality; and the rather, as, 

* if 

f64> -A" f feEAtlS:*- 'dtJ • '^ 

* if tk* aftittial 'was'not'Wadi niy mddibd 

♦ tf 'treatment cdnr do-^em no hahrr. ' 

-•»».^|*iji f \ ,\' .'^diL 

. • * * 

>TH'1s is my method, diflfeWtit^ irt 

* fome mcafure from that of M*' Deffatdt\ 

* but I dare vcftture to fay, that mine is 

* preferable. 








Mercurial oirttmcht.upon the^oondcd 
pitt, '. fc^pihg topeticthe wound 'as mtrth' 
w^'JjoflSble, that this oifitmdfffmay pe- 
Mti^ate into it. ITie next '^dd^ I it- 
peat the unftion on all the wounded 
limb, and purge my patient with a 
dtWjhtfl 't)f the merVJuflil ' spiffs.' ' • iTHe 
third day, after rubbing in 'titer 'diirt- 
^aent only on the bitten part, I give the 
patient a merouiial pill, or r^:6)urth 
part of the ddfe under mentioned. I 
I ctotttmiie thiiS'for 4en da}^ td* rtrb lA 
a drachm of the'tjihlment^ every^iiibte 
ing, and to gtve^'the refolvcAt liblus*, 
which commonly ^rodupefe the patieht 
twd or three Aools, and prevents the 

* Mercury 


* Mercury from affecting the upper parte. 

* At the end of ten days, I purge the pa- 

* tient again with the fame pills, and dif- 
^ mifs him* 

The Mercurial Pill*. 



Three drachms of Crude Mercury, 
extinguifhed in t drachm of Tur«- 

* pentine. 

* Choice Rhubarb, CoUoquintida in pow^ 

* der, Gutta Gamba, of each two 
f^ drachms. v 

' I make up the whole with a fufficieot 

* quantity of clarified honqr. The dofe 

* one drachm. 


^ One ounce of Crude Mercury^ ea^tin^ 
< guifhed in two Drachms of turpentine. 
^ Mutton iiict, liiree ounces. 
' Make an ointment of the wboki. . 

M *Tbft 

> The quantity to be rubbed in at every 
* undion in this difcafe, is one drachm'. 

* I MAKE ufe of mutton fuet hfere, • bc- 
caufe the heat of the climate hinders 
the hog'^ lard from preferving the con- 
fiftence neceflary for an ointment, 

^YlfE method I have dtfcribed, and 
the continuance mentioned, are cmly 
proper for thofe who apply immediitely 
after being bit : for when two or three 
weeks have pafled after the bite, it is 
evident we muft increafe the dofe of 
the medicines, and continue the ufo of 
them. for. a longer time; beclufe ithc 
difeafe has taken deeper rootv It is not 
neceflary to obferve, that the dofe muft 
be leflened to children in proportion to 
their age. For them I dircft fmall 
quantities of the ointment to be rubbed 
in every day for fifteen days, ahd purge 
them once in three days with fyru|>'of 
rhubarb, ' • ' ' * ' ' 


C A N I If E,' MAp^E S,.S. 1^3 

. ;* I HAVE remarked, thaf. children and 
^ young people are, in general^ more fuf-. 
^;^ceptible of this, , contagion^i^ -jthan thofe 
Ipjf an adv9iu?ed age. . ~ , , ; .._ 

s- / . 1 • ■ . . . ■ • . , 

• >■<■ • oL'.->l.'At>.. .J '.t 

. / As to regimen, I forbid xny patients 
Ithe ufe of things tart or acid, and all 
f . crude meats, or fuch as* are hard to di-: 
f.^geft. Other wife, I' give, them entire 
'.liberty to eat what they plcafe,. 

. '. ^ ' 

, * Bathing in the fea has hitherto b^en 

* looked upon as an infallible prefervative 

* againft the Canine Madncfs* The ex- 
f perience whiqh I haye had pf it in all 

* thofe patients who were not treated ac- 
/cording to. my new method, Jaas proved 
/to. pie the falfity pf that opinion. They 
' bathed themfelves every day .in the fea, 
/.but to no purpofe; not one of them 
,* furvived th/s bite longer thsfn thirty, or 
*: three anci,thirty days. I do.not, how- 

* ever, difapprove of thefe bathings, 

* where they ferve to quiet the minds of 

M 2 « the 

f64 A^ -TREATISB i^N - 

the patients. Befides^ the Indians ufu-- 
aHy bathe thcmfelvcs every day. We 
Itre iituated hereon thefea (hore^.andiif 
h ti mattdr 0F iiidifierence whether a ^cvir 
waves of fea- water pafs over their \t6r 
diesy or they waih themfelves in a pond. 
In this hot country there is no danger 
of an obftrufttd perlpiraiioa or plcnri- 
fies. If I were at a greater xliilance 
jfrom the &a coafl, and in a cold Qoun- 
try, I would have nothing to do with 
fuch fort of remedies^ which I look 
upon as entirely ufelefs in the cure of 
this difeafe. 

* Whek I had been taught from the 

* learned differtation of M. Default, the 

* method of giving Mercury to prevent 

* this madnefs, I did not fcrupuloully 

* confine myfelf to his method ; I found 

* it too tedious : for why ftiould thirty 

* or forty days be fpent in curing, this 

* (Jifeafe, when twelve or fifteen are fuffi- 

* cient ? . 

* This 

CANINE^ '!VfVVt)^f^ES*S. J65 

* I 

'* Trt IS author makes ufe of ^e Mer- 

* curial un(5tioh only three times, viz. the 
^ three firft days. He tohtents himfclf 
•-«• with giving hfe patient the^bittef pow- 
^ dfer of Palmaritti during the thirty or 

* forty days 6{ the cure. But I httve 

* ittiore faith in "the efficacy of Mercury 

* kgainft the poifon of this diftempcr, 

* than in the powder of Fdlmatius. Mtfr- 

* cury internally and externally liled, 
/* tho* in frta^ll quantities, appeared to me 

* much more capable of diffipating this 

* venom, than any other medicine. For 

* this reafon I ventured to make the pa- 

* tieiit take evefy day, a fmall i?efolvent 
^ bolus compofed of Mercury, and I 

* have never had reafon to repent this 

* pradice. 

•> . ■ * ■ * 

' Altho* the method I have ufed fel- 

* dom excites a falivatioh, yet it fome^i 
. *' times happens. This gives me no 

* pain : I continue my ufual way. I had 

* rather fee a patient under a falivation 

M 3 * for 


* for a few days, than mad. The Mer- 

* cury, however, goes off hy ftool, with- 

* out any trouble. 

a , ■ » • - 

* Most of thofe to whom I have ad- 

* miniftered this remedy, followed their 
< ufual employments, in the fame man- 
^ ner as when they took ho medicines ; 

* a matter of great importanee in this 

* country, where people are fo poor, that 

* if they leave off working two or three 

* days together, they are abfolutely in 

* want of neceffaries. 

* I KNOW not whether this diforder 

* was formerly attended with different 

* fymptoms from thofe it is accompanied 

* with in our davs : but I have never 

* feen one of thefe mad perfons mimic 

* the creature that bit him, as is gene- 

* rally believed ; nor have I ever obferved 

* that thofe affe(5ted were feized with fits 
*' of ra?e at intervals. When the difeafe 

* is manifeft, the perfon dies on the third 

* day. 

C A N I N. E . M A D N e S S . i£^, 

< day, and feldotn continues to the fourth, 

^ as the firfl: fit always, carries him off, 


* It is an error to believe, that the' 

* frothy Saliva of a mad perfon infedts' 
^thofe who touch it 5 for in my pre- 
^ fence, feveral perfons have walked bare -^ 

* footed on the Saliva of a child that died 

* die fame day raving mad, and not one 
^ of thofe who had touched the Salivai 
\ or walked upon it, contracted the leait 

* injury. This Saliva^ov Haver, can do no 

* harm, untill it has penetrated the flefli, 

* and palled into the blood. 

; • As to the furious defire which fome 
Vpatieats have of biting thofg who ap- 

* proach them, I never faw it, but in one 

* young man, who bit two women, his 

* relations 

^ * The fadt which I am now going to 
f Telate at large in ail its circumftances, 

* will fully prove the efficacy of my me- 

* thod in curing this difeafe. 

M 4 'March 

I ....... . . ' . • ■ J . • t .'*'•»• i ■»)' ^ *i *f 1 • 

, \Mw^b z$f \ 1753^ * young Indiarr 

«,x]pppvef t was brought to mc:. he w» 
*,bctwwn ih}rte«n rand .fotirteca jearsP 
< 9J4j^ ami they I9I4 me th&t he had a; fo-*^ 
' vcr with fliiverings, ^ I iaflccd^hen.he 

• was feized with it ? they made anfwert 
^JLaft Qight. I feli hiS: hftadt/ ^nd ilbund 

Ith^y w<^re cool enoughj; and/ did ;ti9ir 
^pCTCcivc any fcver^ . J gftw.himxfome 

* JFebrifuge pillsi made withwocoawood,' 
•ilheOjc Bezoar^ and Colomha .r<K)t/iatd 
^^ordered him a Ptyfan to.. drinks .with' 
rCryftal Mineral and Liquotiec* . - ^^v 



^/ ' 

^ NfixT dayi, the 26tiiv they, broaght 
* him bick much in the fame conditioit. 
*^I repeated his medicines. : . ^.i- 

; * The i7th he was brou^ > again/ 
*ibut I could not perceive any other dfc- 
< teration in the boy, than that his face, " 

* and particularly his eyes and ey4ids, 
*^were convulfed. I attributed th«fc 

* fymptoms to worms, aod gave hinai.a 

' dofe 


CA N I N E ■ M AIX^N E S S. i^^ 

< dole of cathartic piUs> which procured 
%&mx or five ftools and vemited- hirn 
^threo times* » I'fent.him a finkil dofc 
^.oEDia/corJium, to be taken that irigHtat 

< bed-time. He paffedthe night wither 
*.out flecp, and in gresH anxiety. 

, ■ } 

.j^^ Thx 28th in the morning, when the 
^>patient was brought to rtie, he feemed 
fto be a great deal worfc; his hands 
fwerefomewhat cold 5 his pulfe fmall, 

* and vfcry quick: he had a confufcd 

* look; his face, eyes, eye-lids, and lip$ 

* were frequently convulfed ; he ipokc 

* with difficulty, and his words were in* 
' terrupted with fighs. J fuipeded there 

* wa3 fpoie poifon or venoms. in the cale, 
<^ and enquired of his parents^ if he had 

* eaten any thing that could have occa^*- 

* fioned this difordcr, or if any animal 

* had flung or bit him ? They anfwered 
^ no. I alked the patient, if he remem** 

* bered having been bit by a dog ? Yes, 
^ he faid, he had, and then fhewed me 
' his right handj^ which was, marked in 

^ five 



« five or fix places* by the teeth of the 
^ dog ; and thofe parts were ; elevated 

* above the reft of the fkin. ' Tfie dog 

* had been immediately killed Akty days 

* before he feU ilL 

« I THEN made no doubt it was the 

* Rabies i but in order to be more certainly 
^ con\^nced of it, I ordered a cup of clea^ 

* water to be brought him by way of 

* medicine; At fight of the vfater, hi 
^ flipped haftily out of the hands of his 
^ parents, protefting, with an air full of 

* terror, that abfolutcly he would not 

* drink a drop of it. Thefe words were 

* accompanied with feveral violent con- 
^ vulfivc motions, which were plain evi- 
•^ dences of his diftemper, and of th6 

* ihort time he had to live. 

^ Without delay I had him carried 

' to church, to receive the laft fecra- 

^ ments> fearing left the phren^y, which 

' comes on always, with more or lefs -vi- 

* olence, at the approach of death, might 

* prevent 


* prevent my adminiftring them to him. 
^ After this he wascarried home. About 

* three o'clock in the afternoon he bc- 
' dame farious; and bit- two ' women his 

* relations, in the arm, who attended 
'him. One of them was about fixty 
^ years oldj and the other thirty, • 

^ As foon as I heard of this accident^ I 

* went to the patient, and took care to 
'* have- him tied down, in order to pre^ 

* vent further mifchief. H^ didd about 

* eight o'clock that night. Had I known 
■^ his difeafe fooner, I had probably fared 

* him. 

'^To relieve the women, to whom this 

* misfortune had happened, I ordered 
' fome of the Mercurial ointment to be 

* rubbed into each of their arms that 

* had been bit. The eldeft of the two, 

* who as fhe was bit firft, was in moil 

* danger, was very careful to come every 

* day for my medicines, after having 
♦bathed herfclf in thefea.. 


« I treated her in the manner before 
^ mentioned. . She was purged the firft 

* and twelfth dgy with a dr^hoi' of the 

* mercurial pills* Jn the interval Qic 

< took daily a fmall mercurial bolus^ and 

* had evQry day too a drachm pf ^hc mer- 

* curial ointment rubbed into the bitten 

* arm. This wopnan had three or four 

* ftools a dayi and during the whole time 
« of the cure I obferved no other fenfihl^ 

< efFe£fc of the medicines. She had a 

* good appetite ; wets usually employed in 

* her domeftic affairs ^ had not the leaft 

* appearance of a. falivation ; and has al- 

* ways enjoyed good health for the two 

* years and a half fince this accident hap- 

* pened. ' , 

f The other woman who was bit be- 
r haved other wife. She came to me the 
^ two firft days, but did not return again 

* for three or four days. I fent for her, 

* and upbraided her with it, acquainting 

* her with the danger which threatened 

* her. 


her, if (he left off ufing the medicines. 
She fubmitted to a third, undtion, then 
left ofF coming ; contenting herfelf 
with going to bathe in the fea twice a 
day for fifteen or twenty day is. She 
now thought herfelf free from danger, 
by her bathings, becaufe fhe had hcpn 
well in health to the 7th of Ma^* at 
night, which was thie thirty-ninth day 
from the bite : but (txc then began *to 
feel a heavy pain in her head, as iiie ih- 
formed me by meiTage, 

* I SENT her half a drachfn of oilit- 
^ ment to make a flight unflion upon the 

* arm that had been bit, defiring flic 

* would come to me next morning. She 

* came, after having bathed In the fea. 


* fhe was infeded with the fame difeafe 

* as the boy who had bit her. I endea- 

* voured to infpire her with confidence, 

* tho' I confidered the pain of her head 

* as a fymptom of approaching niadnefs. 

« It 


, * It is true, that thirty days is the 

* ufual time before the Rabies commoBly 

* (hews itfelf, but the delay of nine days 

* might be occafioned by the three unc- 
^ tions (he made ufe of at the be^niag. 

■^ Be that Wiill^ I made her taktf a 
5 drachm of Mercurial pills. .She vo? 

* mited twice, and was purged nine or 
< ten times* 

* Next day, having bathed herfelf 
« well in the fea, (for jQie had fuch a fan- 
^ cy for this bathing, that I let her ufe it 

* as much as (he pleafed) (he came, and 

* told me, that, notwithftanding her be- 

* ing well purged, (he was not relieved 
« of the pain and heavinefs in her head ; 

* that her head was become- infenfible, 

* and like a piece of wood (thefe were 
' her own words). She added, that (he 

* had pains ia her neck, breaft, belly, 

* and particularly all down her back. I 

* gave her a laxative mercurial bolus, and 

* ordered 

C AN I N' E-. M.A-D'N^E S"€. ^75 

^ ordered three drachms of the ointment 

< to. be rubbed into her back, and the 

< arm which had been bit, 

*'Th.b day following,^ M^ loth, .1 re- 

* peated both thofe, ; A cup of water, 

* which I made them offer her, affected 

* her ftomach, and made her draw back : 

* neverthelefs, by mypcrruafion-flie over- 

* came her relud:ancy, and drank a little 

* of it, but threw it up again by .vomit. 

* The Hydrophobia characSerifed the dif- 
« eafe too plainly to doubt its being the 
* ' true \Rabies. 

* It, is ufual for thofe who have this 

* laft fymptom to die the fame day, or 

* the day following ; which I have Jci^rri- 

* ed from frequent experiences The 

* bufinefe then jnoft preffing, wa6 to pro- 

* -cure the facraments to be adminiftered 
'^ to her. 

•. * After this, not defpairing of a cure, 
^ I direfted to be rubbed in, at night, 

• three 


^ three drachms of mercurial cintiilvftf 

* over her whole body. Next morhiiig it 
^ was repeated.' At this time the jpatient 

* kept herfelf in a comer of the chani- 

* ber, and would neither eat fiordritik. 

* Under thefe ci/cumftanceft a fdlivattoo 

* began, which I looked on fts t:)f ft^ 
^ vourablc prefage. I repeated tfae^^ttuftidfi 

* again at night, widi three, drachmr dT 

* ointment. In the night flie faliiited 
' much, and the nekt day found her liead 

* confiderably relieved. TVo flight Uric*- 
•tions, which were afterwards made 

* with two drachms of ointment eatH 

* time, kept up a plentiful falivation all 
« that day. 

« TiTB day following, which was iSM^ 

* day. May 13th, £he found herfelf ^ 

* well, that (he went to bathe in Ae (fca,, 

* She came alio to hear mafs, and to de^ 

* lire medicines of me. The fight of 

* her, and the change in her condi- 

* tion, furprized me agreeably. I haJ 

* the curiofity to try if the Ifydropboh& 

* wis 

^^l^iffts gpne : (be d^aiik, thoiigh> in/i:eed> 

* whiii fomc difficuj t j^ half 2n cup of w^*-^ 
^JteX:. : I agaia repeated tfee Uiw^ion^^, 

* (but made them flighter) morning and 
^ ,euefiing» Son two days longen. The &- 
^iOond diiyf ai i^ht» there came oa • a 
^ ©yfc©teri<? purgingi^ I was: hot jsi th« 
'^ ieait ahiFmcd aK it. J ftrengthcaed' tli« 
» patient inwardly with a littte ccaife^pn 
« «if Hyacinth. The falivation^ piHgin^ 

* WkI dyfcatcry continued until next dayv 

* when^ not obferving,any .furtber fignfrof 
^ illnefs^. and the Hy<ircpjbo^. being. q^tc 
f gai>e> I gave liieir an ounce of CatboJkm^ 
^'madewith a double quantity of . rhu^^ 

* barb, which purged her gently, asnd 

* flopped the dyfentery and purging, oc- 
^ caponed, by the Mercury. Aft night .-ihe 

: "^ look a dofe of Dm^oril&um^ aad next 

* diay repeated the iancie remedies morn- 

* ing and evening. 
<■ • # ■ 

^JjiA^TLV, byme^QS.ofan aftringent 

* igai^le, I failened the patient's teeth, 
^ firhich ha4 been a little loofen^df and 

N 'flic 

^ ftlfc did >ot loofc <»i«' of them. The 

< cure was in this -manner happily com' 

* pleated. She is now in perfed: health. 

'^I 8HA1.L not here relate tmai^ 

* berlefs other inftances of the efiica- 
« cy of this methocL I can iafely ,dc- 

< clare, that I have treated^ with equal 

< fucceis* tfitn, women^ children^ i Ih^ 
l/liaw, Portugueje, Blacks, Melatim» 
^ and Armenians y more in pumber ^n 
^ three hundred perfons, without ona ■ of 
^ them being afflidted with thC' i leaft 
^* fympton) of madnefs i and all thi& iifice 

* the year 1749, when I began, to make 

* ufe of mercurial unftion* I do not pre- 
' tend to fay, that all thofe whom ^ tnsftt- 
^ ed would have been mad, if they^ bad 

- ? not had recourfe to my remedies, . But 
1 iince fo many perfons, bit bymad aqi* 

* mals, have been kept free from- the 

* fymptoms of madnefs, the matter is be- 
:. * yond all . difpute, fincc the cure of the 

- Sgreateft part cannot be attributed Jto^finy 
'^ thingtbut to the effis^of the remedy I 

-... ^ . * have 


t* hav^-copftantly made ufe of oa all ocr 

»• .*. • • 

* At the time I write this,' J have un- 
• der cure five perfons bit by dogs fup- 
-^jpofedtto bave.been,mad : dicy areaii in 
"^.^a fair^wayof rcaoverw. r^- -m - ;..- 

r : * .1'. » . , , . 

- I .-*••■. t i >A. t • • .' ■ • ! -.J, : • ' 


:' I*HiNic layiiplf.qbliged to the.^trau- 
ila^OK'ipf;: this,^pamphleti^ whoever he,, be, 
for h^viag Mcri$f dr;thp dU?overy of the 
viftaes of 'Turfietpi Mineral to me* JB.ut 
:inr::hi8.addl:ej(§ ,Jo the reader there is a 
fitosH . .cl3tro^]<9l9gical qrror, of no great 
coafequence. He fays, myjfew method 
<f\.furing madnefe; &c. was read before 
like; Royal Society in February:^ 1741 j 
whereas my Memorial on Caninej Msidnefs 
was laid before that fbciety in 1735, and 
:! d0:.Qet' know that nay paihphlet pub- 
lifhed ia i74i> Was eyer read there. 


This gei).tleman, alfo, feems to think 

7urpeth Mineral too irritating when the 

throat ^Si^ fauces are inflamed* But, pro- 

t * N 2 vided 

• • ■» 

vided Mercury will curdtlrA diftiimpcri I 
will not difputc with him about -the- ^par- 
ticular preparation of that mineral^ or 
Which h hitJft fuitable; ' ^- 

' • 'tnt feaffin WhSV^feVgry ' that M de- 
termine me to*itletfe» itfc, tiiatk df 
all the mercurials the mofl powerfaI> and 
-ixerts its efficacy '^e-'feiiMCfeft. Th* it 
•ihiayi or - fhtlj^ hot^ fcte'gi^^, iri'^fflcfe't 
'tnannen. ii^'ib 'excite no ftrong effbife, 

• ri6r any diftirrbance in the -body ^ - tfftd 

-that when ufed as an bihetie, when--ft 

perfon is aftufiilly feiircd with tfeis fpecies 

of madnefs, fol- that very reafori- it pfO- 

d\ice^ very pdvC^erful, iMportaiit^jind Jiat««- 

•tai?y;fefFei(3:e> without injuring the* coii^ 
^ftitutibii; • ■ • : • ■ r : .... 

» • r 

• AF^fck r had -refided feme* jrcars m 
Z/(?;^^<p;f^ I'cbiiihitmicated 4hc fuccbfe rif 
the Turpef/j Mineral to Mr. Scawen of 

'Wdodcof Lodges' ne^ri}apiik(m m Surty^^ 

• -^^16 tried it in a A-eat numbcF of cajfe*. 


, 4 ...11 I .»-.• 

th<?; following i^t^r,^ ^jd^rb m 4^ jOv?- 

■ • • l -.»..) fci > . 1 L ...... a^^ A . ^ f ^ ., « 4 L 

.' W/mlckt Lodger I S^Ai^ 

I Pear Sir,^. . . . ^ . r 

UPON ihfi ftriifteft tnqouy of JfcGifrr 
/e» (/i6tf huntjman) I know but of 
^i^ inftance -where, /yoiiu: Im^dKaiite ;has 
mi^arried^ and that was^d ^vc it}t«>a 
faonixd; dinfi x>r tea days ofter^he wa$flHt» 
and had iS^t^HyikopbaSiavA I begap wtith 
tW3clve gradns of .^T^r^f/ilibr^ihie firflidofe, 
twentyrfoBK for- the : fea»uU anxir4:hirty-J$x 
&r the thurd. ..He was ibemingly "Well 
between each .dofej but after the third, 
continued well for near twelve hours, but 
then relapfcd. I repeated the TurpetA 
fls before 5 after which he continued wpU 
for near twelve hours, itheo was ill again* 
I Went on jio further ;with the experiment, 
l)ut ordered him to be killed. 
j-^*'" N 3 The 

i8a A TiEA'Msi''^¥r' - 

» A i» i' 1* 

inipfece'Wth>5«;' into ' Which'^e 5^^ 
/^/i& is ][)»« r then givtf^hifd i"piMe%r 
two of clean meat, which if he tJsM 
freely, then give him the piece that is 
baked. Butjiiathe firft cale, when the 
dog is mad, mix the ^urpetb with butter, 
which put on the end of ^* ftick, and 
thrift It dovifn his throat. ' y 

'-*As fooiiir^as'I 'know a dog to' be bit, I 
ordftr:^him*i3(p Be.blooded, and then give 
himoe%htigrains;for die £rfl \do(e, th4 
fame quantfty for the fetond,.aind twelve 
for the third, iTeftin^ tweftty-four^htmri 
between/each ^iofe;/ but the Hkeqiianticjr 
in three dolei^ has been carefdly repeat^ 
at the next period of the moon. 

^ .— 

^ I HAVE -vAry* often tried the experi- 
tnentj and always with faccfefs, eswept in. 
•the* cafe whrch I have already mentioned: 
J have now ohe under cure, and doabt 
not of his doing well, as it was given 


hifn the day after be was bit ; for I re- 
alljr belkrve ^the . ^ukpethi .ta. be;;a vfipecific 
fon'thcJnte pf^.4nud dog^ji^whe^.taken 
in^' juuG time'/ ^ • ^ " -> '^ • - • • ■ * • • ** "■* «'.*'>'i * » *■ • » ■ ■ •» . 

- • ■ . - .J 

I HAD the honour ofreceiving the fol- 
jb^tng"* fetter on fbiis fiibjefl: "from tile 

late Earl of Berkel^. ' " 

,1 ./ • - • II I 

.«■ *•- ». '1 .>*\ 

IA M fo thoroughly perfuaded of your 
good intentions for l^e benefit- of 
iHacikinid by all your' adioni» that yea 
may ! make ufeof my name;: and the 
things^'that iiha^TOxxperienced.:: i .: j 

:j $ 

. The firfl was on my pack of hounds^ 
gwgO:jne::by .1^4 iQfford three or four 
yfttFs ,agQ> \yhicb I^idlboth fbrts .of madf 
nesfcjtithc. reiving: smdjtbf? keinjej -miadDeia. 
I- l<^;,feveral couple till I talked .with 
you, and„ had , your. famphJc^. J .then 

N 4 im- 

# ■ * 

jr«4 A f T R EAT IS B j ll2ilX 

knmediately gave all my hounds in.'g^* 
iieidLr&jQimieidjcine^ tlulfe tliattmfaw bit^ 

a madnefs from that day to thioiii: dtjAtaui 
two dogs mad at th^\r4fiue time ;;; one of 
them had>b€en tied up, three days, and 
had eat and drank nothingj^ fo had not 
ilrength td *^ through the remedy « 
That ivliich was jcured had the fbongeft 
j^mptobis oif madnefs,^ fuch as the daread 
of water, biting at apy things -aiid ,ber 
bark was altered frofti a little voice, to 
that of a great dog ; ihe w^ aur^^ 

f J - - . ■ 

My nbwther 3*b^'s hOunds that were 
mad, had token all forts of drenches, to 
:thc ©umber of iriae or)ten, but it did not 
do. I immediate^ .>gai^ him:yotir re«^ 
ceipt, and he gave it them, and he ne- 
Ver had a dog mad ifterwardsv I have 
actually -now five Tpsniels and hounds 
juft bit^; I have giWn them, alio, your 
medicine : they have jpafled a change, a 
iullmoon> and another change, and they 
are afi well, and jiot one gone mad. 
- . You 


-■ Yoir<'HUiy>audce v^Kat'vdc yiixt fdcafe 
of iha& idtter^ i hare: fcttt.aft idut I 

*):J DTD once meet '^iti% Mt^ilqiim/^ 
dbittofit £3x-hounids^coiiuiig tdbey^xpdt 
lifid;!tdld his buntimiai'^ of your cxtoe^ 
i)Ut^know not if be xtf^d it ; but^jishi^may 
anqutreu' He lives dn Hertf^J^wnfilQ 

* Jam, Sfr, y^uf^ .i-' 

I ; ■ f 

k « « 

t * .• s .■ 


P:'5: I am net furei but I thanfk liiy 
Brother's hounds took Mead's medicine* 

» . » ■ 

Milton HilU near Pujy, 
hy HMgetford B(ry, 


1^ . .AvTH E;A-3P4 $i&^.-fiaf ■ :> 

:,Ta£. two 'foUof«/ing'^i:aie9 ywem^ 
coxiicbRiiubatfid^Jto :tnQ hsy th& Rigbt JFiOm 
noarable the Counted of Bucbauk. . ^i-^vj; .-^r 

^l^i^Jufyf 1740, as Margaret Bwyatthd: 
JikM^der'Logan^ a youth; of fifteen^ firt^ 
vrnite tD Lord J3//Ci&as,i:.ivere:.ftaQd^ 
thoidtohtnv a- fiieep dog, belonging /to 3 A\ 
kboftirmj^^jhw bar^ hy^ came in# wMcb 
at firft did not alarm them, as he. ttfed !». 
do ib, and had nothing of that wildneis 
and fury )b his .look, that could make 
them aware of him ; the reafon of which 
was owing ito his being what we vulgarly 
call filly mad, andof courfe, as we always? 
obferv^y ' upable to bite, or at leaft but: 
fiightly, by reafon of the debility . of . the 


under jaw. 


He firftcameup to the maid, whom 
he fnapped at as (he was ftooping for- 
ward ; and though there was nothing but 
a flocking between his teeth and her 1^^ 
the wound was fo flight, that it hardly 


CANINE: M. A I>N E S S. 187 

brought tJifi .blood. He • pext jumped, 

and caught Alexander Logmhy the han^ 
but had not ftrength to make a wound 
deeper than < the former^ .whickjalfo 
hardly ..bled,' bujt the ffcin : was .(nu^ 
ruffled. - : And, feftlyi ^g,;jufn^4r^t . » 
little girl; who, and .attempt^ 
to bite- her arm;* but as it was, 9WSf^ 
within her gown, there; Lwb§;ri}QtJlji\g. tQ 
be feen but a rednefs on the part, and 
the fkin not in the leaft;brQket 

J ^ I 

'■^. :^;\ 

As we heard of the accident the mOf« 
ment it "happened, we fent exprefs. to the 
Earl of Hopeidun, with pur compliment^ 
and to beg his Lordj[hip would l^t; jis 
have what he had found by experience td 
be the mqft fuccefsful remedy for the pre- 
venting madnefs among his dogs ;. which 
he did accordingly, and it was thus. Na- 
tive and Fictitious Cinnabar aad Mu£k, 
in equal proportion ; but for the quantity 
he could not pretend to determine, as l^e 
had never given it to aay creature except 
his dogs i but ?dded, th»t Jio doubt the 
. ? apo- 

m A vr£A^Ti:$EroN^ 

apothecary we employed could infbfm ns^ 
w make a giftc6; ' 

L ■■•*•■'■■ ■■ ' '^ ' . . . f\^ •*<■ • •, . . ' I . : 

^'-^^<^si^»l1im.Y;■hy ithe • dtf eaion • of 
Se letter, it was linimediately 'admini-<- 

I * * * ■ 

fiettd-; but the 9aav from a nUy notion 
\8iMi lid ix>\M^r ' fro^ f&-%fat i 
ienfS^i Haet*; «e ^e^^urid itfter;>thrcrvni 
imay' tiie one^Alf; ■ ' . 

In the mean tifhe^ (he^ who was cDil^ 

illtutionally very fickly and hyfterical, 
>ir» worked fey ffi6 medicine ib vSdeikly, 
tn^cSve had rea^h to believe it vi^ould 
fcave ^one hard with her> had not a |Ay* 
ikian, who was accidentally in the houfe^ 
given her fomethirig to le0en its viblencii. 


Thi: day after it was repeated in ft 
]eis quantity, and worked moderately on 
her ; but the boy, from a fuperior 
ihength of conftitution, found no cfk6t 
at all from it ; attd on having a ftronger 
djofe repeated, confefTed afterwards, that 
lie threw it again over the window. 


€ AiNi N E . M ADK:^ S,S, i{^ 

■ V 

. In the mean time^ as the thing was 
not fufpei^edy the ipedicine was not again 
repeated to either of them^ and they Gon« 
tbiued well for a week or the 
end of which tithe I ohferved one day^ as 
he was. &nripg at^table^' that his chops 
were tied with a handkerchief, and de- 
manding the reafbn, he replied he did not 
know, hut they were fwelled, and fo that 
he could not chew with them^ though 
he had ho pain. To which I anfwered> 
in order to frighten him to take ttnbther 
dbfe of the medicines, (having then heard 
what he had done with the former) thit 
I, fuppofed his chops were going to fall 
}ike the mad dog'^ that had bit them ; 
which made no * further impreffibh Oil 
him, than to make him repeat it as a 
a good joke among his fellows below 

AbAirS* • - -• - .... 

% * ' . 

In a few da)rs after> he being ferit to 
the well to bring in two quart bottles of 
water, the fervants were alarmed to fee 


him enter the kitchen with a wildnelfs 
and horror. in his look, and^ without iity- 
ing a word, run to the fire,: aniput two 
€odc6-intOLt, faying; its tohhimMfi I am 
hn^cb^di hut sthiinmll do I dr fame ^Inrords 
to that purpofe-7^:and being 'deiiired to 
cx|^n himifelf, he: gav&i t{ie:iicx^)ant.'a$ 

ibilbws. • .' . , J' i ^ . .' /:..;. h:.r r ; • 


.That being fent for ^ the : water, he 
ftooped down to fill the bottles, i but had 
libtfooner heard l4ie Abife it made in go- 
in^- down, than he was fei^sid JAdtb fiidi 
4 fit *of firight and trembling, that he fet 
them down, and rati as hard- as he couki 
from the place ; but recoil eftirig that the 

bntler, who wanted the waterfor fiipper, 
would be angry if hedidnotljringihem, 
he turned backj bat no Iboncr touched 
them again," but the fright and trembling 
returned ; fo that he could not . have 
brought them home, had he, got the 
world for doing rfo/ By thit,v added he, 
I know that I am bewitched, but as I 


CAtllNE M-ADNES'S. igt 

have burnt the corks, I am fure I fhall 
be well. 

After this,- he fpoke a great deal of 
incoherent ftufF, cried out for a Bible, 
which he immediately threw from him, 
wept, and fpoke in the ftyle of a perfon 
under the influence of a deep melancholy, 
which was the more remarkable, as he 
was a young lively boy. - • 

Upon this, the clergyman, a fcnfible 
old imn, was fent for, who, after tall^iog 
to him. a little, came and told us, that he 
-fufpeded his delirium vrz^ of a natujre out 
of his way. 

. In a \ivord, concluding that it proceed^ 
>cd from the bite of a mad dog, the apo- 
thwary was fent for, and the medicine 
ag^an frequently repeated ; but we have 
fince regretted we did not try whether 
the Hydrophobia continued. 

f Ik 



Ix a few days he gave over talking in^ 
CQlicrcntly» but the wildnefs in his eyes# 
lod dgeded ftupor ftill continued ; and 
be was fo hi out of bis right mindj that 
be iniiiled to fland as uiual at my hack at 
table. At laft, by making uie of a gr^at 
deal of exerofe, be infenfibly returned tff 
his former health and looks, only that 
for iix months he was frequently, as if, 
were, fhipid, and had the gloomy wild- 
neis in his eyes ; but whether it wa9 at 
the height of the moon, or not> I canr 
not at this diibuice of time be certain j 
though I remember it was fo believed 
bv the fer\-ants at that time» 

\ » r 

Hb has ever, both before and fincc he 
left our family, been in perfedk healdx 
both of body and mind, and is in a good 
way of bufinefs, and has a numerous 

- •- 4 

The preparing this Treatife for the 
prefs has been interrupted, or it would 


C \m N E , lyiA D N E S.S. 193 

have appeared a month iboner. On 
T^hurfday^ Augujl%% laft, I had a »call,ta 
a great diftance^ . to attend . a perfon 

who was fo unfortunate as .to want 

..... ^ . .,•-.-•.._ 

my afljftance, aijd to whom. X could not 
rcfufcit. • Whilft I wa3 abroad, the fpl* 
lowing, very important cafe 0Qcurred» 
which riofl the opportunity of . attending, 
by being out of the way. This,- howe- 
ver, I regret the lefs, becaufe I have the 
particulars of it from undoubted autho^ 
thority, and afterwards from the girl 

Sarah Wharton, a maid fervant, 
about nineteen years old, of a good habit 
of body, was going down Airjlreet into 
PiccadUfy, tht 29th of Augujlf 1760, 
about eleven o'clock in the forenoon, to 
look after a place, when a dog running 
along, fnapped at her hand, and bit her 
on the putfide of the wrift of the left 

O About 

«94 A T'HE'A^TISi^ Xyisf > 

^ About fbor o'doek ^in die aftemootr 
dp the fame day (he aj^Ked to a ibrgeoif 
ki that neigbboarhoodi. On exammiog^ 
ihe part^ he fobnd k was ratfief a fcntch 
4ian a weund ; cuid where the todth (^ 
^tie dog had pinched the ikin^ it had 
nien i»ta a bump aboot the bigneia of a 
pea, round which there vm aft inSkmed 
circle about the ^e ef ar crown jnece; ' '. 

' Mry. 3%»er, m Coventry Comt \SiiSt» 
Haymarkety wkh whom flie Kvcd 't3i fbe 
could get a place, had applied pariley and 
ialt butter,, bruifed together, on the part> 
which the furgeon removed, and applied 
a pledget with mercuridt ointaoent. He 
did not open the part, jndging from the 
inflammatioA thai the poifoir had entered 
the blood; and gave her a drachm of mep* 
curial oittfment to^ rub into the hand and 
arm dfiedt^ ; and four piHs^ i&ade tip 
with two grains ef Turpetb Mmeral ni 
each, two to be taken going to bed, and 
two next morning ; and defired her to 
call o& \i\xx^ at the &mt tioie next day, 


^i^aidi ihit dSd. i«SSe &ow camp^ned of 
topain in the papt;that.was bit; with fly^ 
ijjg paiiis^ in her head ; . a tcrtal lofs of ap*. 
^iiic i and faaid ^ qokk,- bard rfuHrptiMci 
Bhti had then t«»t. dunces ef rblood ta:*^ 
kfiti frbrxi h6r afin ^.and notliavinj| had 
«^ftobI fince the/^cidehti fhe was«<fe£ffl^ 
Intake a clyfter> 'made \tith ai oance d^ 
commm fdit, and a pint of trstem *watftr> 
and if that did not procure a ftool in half 
iachour, to repeat it; and to repeat thft 
j^i91s and oiiitrnent as before; ^ 

. ■ ■ • ? ■ 'ri ' ■ " 

,y Sunday y 31ft. The furgeon vi^ted her 
ffiitif mormngy itfid fbiind the ctyiler had 
ti6* opccatedfifficientljr, -which: Mts^ 
^^;(?^j faid lyas owing to her hot taking it 
properly, as flie was much altered in her 
t^per, and woidd Dbt do as fhe was dc- 
fired^ii ; ; t He* llhercfore ordci^cJiier a ptrrg- 
m^ pHl,- with: threfe ^ains of "CJalonficL 
&i^' complained: i^oSv i^at the pain 
Afe^tlded a^ high as lier fhcufder^ and 
ditere ratfed the fenfatiOa ttrf. rdogs^ bitiiifg 
1^:; and: that^ fhr toxM mot /Bear i\\6 

O 2 light. 

.*!«>. • .4 


196 A S^'EATI^^]ON 

light, nor lcx>k ,at water^ but with great 

... The pill operated fix or,fcvcn times ; 
jLt night he ordered thqpin^oG^nt and pUl( 
a?, before, .as alfo jija petida and crude 
Q^ium. Qf . each four grainst. to be, made 
into four ^ISf one $0 be talf en evexy i(^ 
pond Jipur, until fhe found ^e. As 
foon as fhe took the firft of the quieting 
j)ills;» ihe vomited it up. She then took 
a fecond, which likewife came up^^ycf 
ihe palTed a better night than before* ;. 

This evening the orifice in. her arm 
burA open, and (he wa^.fuppofed to loie 
near a pint pf blood. 

Monday. This morning the pain of 
her arm was much abated, when (he ws|( 
ordered to. take one of the 3"z/r^rfi6. , pills, 
as before. She could not beajr the, light, 
though her eyes were fhut, but was ob- 
liged to coyer her head \yith the .l?ed- 
cloathes> and tbp ilying paiqs i^f^at %ft 


CANIXE ?:Ar>5'ZIl ??- 

complained cf bz h^ V^- T^^rrt •r:::rr- 
turaed into z ziifisriL 

This cvcniEg fibs ts^ laici Vrrr^.- 
Ac pain in her zra c':£:^ r^TKL rte Lir- 
nefs in her ftomaca jsfi rrnar. iz ^Jx 
morning. She tock £ £±ie vzi:^^ 
twice, which ftarcd near twc btnir: 
each time before it C22>e rp, -w^ir: -p^ti 
the firft noariihmest cf^srr Vine it i-af 
taken fince die accixierrt* Sse ^r^r. -sr- 
dd-ed this night to nib in ^ frAr:-!r cr 
the ointment on the ^ScStsi arrr, ?.: Vt- 
fore; to take two TurprfS z:fA, irA 
drink- after them two fpocm^i cf th.* 
following mixtare ; and to takt ♦-» o 
ipoonfuls any time when fick; 2rji or,t 
of the Opiate pills. 

R Succ. Limon. ^ii. 5^£r AMntL Ww 
PuL e C. C. Simp. rfe. S^n e Mmn. !:. 
' Aq^. Pont. Jiv. ilf. 

Tuefday morning. Thi?, n^th on-r of 

the Opiate pilk, gave her a good night, 

' O 3 and 

198 A -TREA*I&i^'^N ' 

and flopppd her vomitiDg. She found 
herfelf much better this aipraing« though 
the g^ddinefs in her head ftill conti-? 
n)ied> ye^- noj^ fo violent ; and (he cofild 
bear the ligl^t much l>cttpr tha^ thp dsfj? 

At ttin^ ijhU mofiung Qm tpo^ a ftur^'- 
ipg pill, <l)e fiupe 9$ '^ndoji l^ft.- Br^ 
Nugent vf^ defired to vifit her inji^md 
pauperis, ^|uch he o^oft t^e^dily 4id about 
eleven o'c|oc|c ; and finding her coqiplaiq 
of ^ diffippHy of fwallpwingi . h? adviied 
an Qun^f: qf ^(Ubanum a(id :^ drachm c^ 
crude Opium, to be fpread ooi Icatherj; and 
applied tp \^^v throat, and round her 
neck ; and to add one gf ain of Opium to 
the mixture above prefcfibedji of which 
ihe had only taken four fpopfltfuls ; to 
take half one of the Opiate pilU pver 
fcribed, and eight graips pf jfffa Feet, gor 
ing to reft, firft rubbing into the arn^ 
affected one drachm of the mercurial 
ointment^ as befpre. 


. ; . » •■ r * 

1 We,dnejday. This monung Dr. Nugeni 

<H^v|be o^^Cmofit* and on)/. OjE4ei«d^.jdie 
pUJ^ftft be rtt)£»teda as lif^<n%bt.:v. ;Vv.v,<v 

- jifTibfcr}^. ^jThis^ mottling .'Atcr'i^i^ pd> 
fedUy well ; oa whkJi .th& /orgcfpii^ 
h^% leave^ defirit% her* if ilie -jthojitkl 1^^ 

;^ 8aiimiay. i8h« ;«omplfttiieclJ[agaiiv cif liCir 
beod^e ^^^ F«^< piUs ^^dtr^peatjad; 

I drachm of i;ho vointment. Sheivicf>iidw 
perfeftly well. 

' 1 • « • .• ^ • 1 ■ * 

»j. . '■• 

O 4 Either 

200 A :X R.? AT irS.E -CVN; 

£iTH£R on Sunday ot, Mondajf^ I do 
liot cxa^ly' remember which, I faw and 

■ ■ 

examine the girl, whom I ibund per^ 
fedtly well. She coiififm^^d' to me tvciry 
circumftance related above, with refpcfl: 
to her own^fenfations. And ^^ce-'tbat I 
had .a]QL' opportunity of >dk:ii}^I>v>iS%^> 
^fnfs opinion of this ^^w who^^^teiM 
not to. doubt of its beings ^^the Ganim 
Madnefs. ^nd he teUi-me^ jitfaat^o^^-jTA^ 
day 9 September 2, the day he firft vifited 
hdr^,- ihe concealed her face iQbrtW^^iir- 
tajns, ^ta avoid the light* -- . • -. .- 

. "^ ' • f-r " •'■ * 

; Dr..CAeyrie, haying giving his -opinion 
of the treatment of Canine Madne& by 
Mercury, in his treatife on the natural 
piethod icif curing, difeafcs-of .the-; body, 
SEnd ( the difeafes of the mfhd, ^ pubdifiied 
in 1742, as his approbation is offome 
weighti r would, not pmit quoting the 
' paflkgcs.. .. .....: 

• - - i 

. - . ■ • ■ 

* Madness 

Cit N I ^i '' ^ a' O li E s's. kb t 

* ^ \ 

* Madness iid^'Ulydrophohid In (3ogs, 

* and rage and. lull in ptner >w«w<2/r,. arife 
- ""ifroife tffe' affeim^.^''-?tod,'fcfmenlati^ 

« df ^-aSiyirialtk'-dlflyT; prticularfy "th^ 
« madnefs of do^Si \i ^bfSfved Id pfbc'eed , 

* from forfeits of carrion and outxified 
••'fieffi,* thejr •ffll&ig-4fieEf*-bld6d aftd juices 

•"iiTe drtacKfedi iand iir'a;ftafe'ofaaivuy; 

* which- ^)Sydrophubta k how (b fuccefs- 
^'fiiny/ind,! think, rationally curei\)y 
« ptJrtdcititis' medicinesV liibre efoecialiv^ 

* Ihit'^^rc' the quickett "bf all in their 

* operations, as lafge dofes oi Turpeiby z^ 

* might '*havc been Jiiftiy expeftedyhut 


« the cure cannot be certain, unlefs It be 
br6u|ht to rife to a quick falivation ; for 
*' as 't}ilt''l^& of this '^oifbn ' is quick, fo 
* m^^tKat'-be ' of its'' 'ii!ntido/es. Me'rcu- 
« rial'iri^Aion, ^^Ith 'a 'Quickfilver oint- 
^ mihti'' and ^he'aftive ponder ofe^ 'may 
« haiteii arid afcertaih the cure in fuch 
^ a dcfpcrate and frightful diftemper. 



■ * And I am fatiafied the Hydropbohia 

* itfelf can only be folidly cured by Msr^ 

* cury^^'yx^Qiow^'f managed,' 

It only remains* that I give feme ac-- 
count of certain remedies, which, have in 
their turns hgd fome reputation for pre- 
venting the Canine Madnefs, and which, 
I think, cannot be relied on> as many 
more have contradted the diftemper, after 
having taken them, with all imaginable 
care and circumfpedlion, as prefcrvativesj 
than have been faved by their ufe. , 

The firft I (hall endeavour to iet a 
naarlf of infancy upon, is that operation 
which is called worming a ^og ; and the 
rather, becanfe the notion many people 
Jiave, that no dog can go mad after it ; 
^dof others, who firmly believe, that a 
dog thus treated cannot bite, though he 
fhould be afterwards mad, may have 

irery untoward confequences, by lulling 
Ithpft of this op^inionjnto a fgt4<9eQ^» 
^hjlft ihey ^rc epnverfant with the 4o' 
fneftic animals, thai bftTC fu^jipitliisi^ri- 
^cslpm crueltjr 

, . .:- .,;.. ■.., ...ii-.'Ut ■ 

I ^AVE ff9q»gntly fgcn 4Pg6 wproicdf 
flfg they caU t Ji and fin4 itthwii ^ 'W^er© 
is in alh«4 ^^yery ()^ 
England, Ibme coblor^ pr : fent^ri^^d* 
feontfinifl^ tj^at bp^fts a cjejftcrity^.iiinrti;^ 

|;ing a worm from under thetOQ^VO^iif 4 
pttppy;^: 'Their fee is tttiwrlly fr©mi la'Aasi 
}ifig, £3r dogs of th^ mqre genial fj^mi 
fi penny, or a mug of ate^ fbr- cxuSi 
They elevatsfc thp ' tongiief:^ and ^ with^ i?att 
awl, or a penknife, or fome pointed in^if 
ilrameat,:a;aJi:e:ir piui^rp^ ub(}er it> lane) 
^aw OQt a very; lleiider £iament;^'W^f^ 
I tdsie to, be a';iierve; ' atid dii^i^c^n 
fra&in^ rwbea recently: taken awayv'^ii 
ideot$ ' fancy> itv fU^^ , :a^' jbelk^iie x it^4 
wtuia, to whic}|t;it)l)^^ nq^ tqgQtiee^'^pf 
ian^e» ' ■ * - ;■.>■•■.*>■.> i » u ^-. ^ '■ ■• -u \ • • -i • * i ;) 

« • 


m X WfeV-fiM^gi(r- 

'«H».-^ ■ . ,'-■;. 'jo:^. '■■: 

•KJi I , . • ' ?f »• . I ■-' ■ tr • •r; 

• » » 

' Be that as it may, I tm certain from 
cxpcriehccj that dogs thus treated, run 
mad' equally with thbre whp have aever 
fuftered this abfurd operatibh. There is 
no worm in the part, I firmly believe. 

irid cohfequently none can be taken out 
All that this can do is, to prevent puppies 
from biting or gnawing every thing they 

meet with ; and ' for no other reafon, 

» » i. _ 

tfean becaufe it makes their mouths foref^ 
arnS' gives them pain when they take any 
hkVd thing in their' mouths ; ' and this 
Bf'^k^ tnem of the habit. 

-.fiHt^- - ■ • • ■ ^ ■.'■■■■ 

1 ?, • ^ t . , - ■ 

*' Triis'is intended to prevent a bite. 
But there are many applications equally 
ridiculous, recommended to prevent the 
ionfequcnces of it. Thus the hair of the 
dog thdt gaVe the wound is adviied as an 
a^plicatFoh to the part inj ured! " ' *Bui as' 
the reafon given fbr its efficacy is a' Wry 
bad one, it deferves no farther notice. 
It is, that every animal carries about it 
an antidoti to iis dw^ri poi&n ; therefore 
^- the 


the hair of a mad dog is fo to its owa 

/ • 

I HAVE no experience of the virtues 
of fait, or a hot iron applied to the part 
afFefted by the bite; therefore can fay 
nothing of them to the reader's fatisfac- 
tion, or hiy own. But I muft confels, 
I think them likely enough to do fome 
good, provided their application is im- 
mediate. But I fhould have very. little 
dependence on either, or both, if ufed 
ten minutes after the reception of the 
injury ; for in a very little time the con- 
tagion may have reached where neither 
the fait nor the cautery can follow it. I 
fhpuld therefore efteem, them as very pre- 
carious p.refervatives. 

Perhaps nothing has been more re- 
cominended by way of preventing Canine 

Madnefs, than the river crabs. 

' ■ ■ . ■ ■ ■ > - • ■ 

• ■ ' ■ ■ 

. Diofcorides, in his treatifc of the Tberi^ 
aca, C. I . gives a very excellent dcfcrip- 


io6 AtHUATt m''^im(- -^ 

ikxi tif- ft mad d6gi 'Im G. 2^. lie yectiffiM 

mends a medicine, which has hocttitkitA 
notice of fince by almoft every author thaf 
hnrtttote tipoiti the ibbjedt/ - ■'■' 


'■ It cbnfifts of the afli^s of the ^ife^r 
<t35'^ ('ieitwiVaOf ■Jr^atjttibuy, ) bUmft 'ISy ^■ 
&6 iAz^ 6i th6 t6ndrii^ of tii^ i#(iit<; 
vine: ' 1;!S(6fd tffe ^dvlfed to'bc'dn^fy tfi^ 
tTirataI> and kept for ufe :' a< a!fo thiJ 
root 6f Gentidii> f^Wderdd a!bd MeS. 

»■»».■ . • . > 

rWftE» fisy tJntf is bhtftri by* ddgi 

r ■ • 

of fhe River Cr&b's, itid one of the pbw- 
dertftfGieftfian, dV6 to be glvenf in fatsf 
ephbioi^^ft vfiVife. Wfieh- &tffc' iKreW 
t&titA and mixed '(cJs *^/ <xX(^iW)' Mrf 
a thlh pultice, or hafty pudding, they 
^tre%6 bid t^uif t'dkeh" fdt foiiV Itys, (I 
Belfeve it mould be forty) tf m%mmi 

' f 

recent;' btliti'^*'ifc the' dbfe firis to" wj 
increafed to double or treble the quanti- 
ty, if two or three days had eliipf<id dter 

receiving the wound, before .it WM a4r 


V I 

Bur though he thitiksr this majrpeffi- 

bly be fufficient, yet he advifes othef 
means to be ufed. He fays; 4 l4%6 
wouod^ which bleeds much> is lefs da^i^. 
gerotis than a fmall ofte. In the larger 
wounds he directs the torn ficih to hit 
taken away immediately, and the lip^ of 
the wound to be cut all found:, and the 
fiefh to be taken out. He further adds, 
that both in large aild (mail wounds deep 
jfcarifications fhouM be made all ^pn^^ 
He tells us al{b> d^at after this, cttppifig- 
glafits ihould be a|iplxed, wid> ixiHcb 
fire, both that the vindence of th^pQiftwi, 
flSwMild be moderatccjf by the fire; andjlhaif. 
the tdc» pwy jsjecp* open the loiigpr. 
He adds, that it muft be kepf opefj. a 
coftfidergble time^ by a;pplying to it.^Tffr 
rklbus ^r^ ifrct^t^^ ) , f^ bm^'fed wild gar- 

•r? ■•. ■'?■ ■ i/- 

oMefli|^^Eenre<^ in brinef or fait ; but properly of filh, as 
mchoviesy pickled herrings^ Caviar, Botargo^ and others. 


lie, or. onions, or the Cyrooiac Juice. 
But, fays he, if the ulcer fhould heal 
within forty days, it muft be torn open 
with the hands, or. cut, -or burnt*, Af- 
ter keeping it open a fufEcient time^ 
when it is fufFered to heal, the whole 
part muft be covered with the plaifter of 
falts ( S'lsi Tm dhMv ) > and after fonac 
4ays he advifes to apply a Sinapifm. 

Galen de^ Simpl. Medicament. Facul^ 
tatibus L. lit C, i. No. 34. lays, that 
the afhes of River Crabs ( w xora/xi- 
mv xGLgTUfcav ri(pgct) adt wonderfully by 
the property of their whole eflence, up- 
on thofe bitten by a. mad dog, either 
alone, or with Gentian and Frankincenfe. 
But there muft be one part of Frankin- 
cenfe, five of Gentian, and ten of the 


He tells us, he feldom ufed them 
©therwife than as old Mferian, the em- 
piric, prepared them, an excellent judge 
of pharmacy, his covintrymaa> and mafter. 



He ufed to burn them alive in th^ 
fummer, in a copper difh, after the rifiog. 
of the Dog-ftar, when the fun was in 
LeOi and on the eighteenth day of the 
moon. The dofe was a large Cocbliare 
{iLox^^^ov evfjLeyiki) of thefe> every day^ 
for forty days; but if he had not the 
treatment of the patient till fomc days 
after the bite, then he gave two Cocbk^ 
aria every day ; and applied to the wound 
an emplaftic medicine of Brutian Pitchy 
Opoponax, and Vinegar, in this propor- 
tion : of Pitch, a pound ; of the fharpeft 
Vinegar, an Italian Sextary ; of Opopo- 
haxi three ounces^ 

The Fix Brutta was the fattcft aha 
inoft rcfinous kind of pitch, fo called 
from the country of the Brutii, where it 
tvas procured from the Tada, mountain 
. pine. Thefe people inhabited that part 
(^^alairia, which is over againft Sicify, ' 
beyond the Lucani. They loft their li- 
berty for joining HannibaL 

P I 

2:ro A tREA>ri8e'ON^ 


I HAVE been the more^ particular, ia 
Acfe quotations, in ferder to {hew the 
ricceffity there is* for accuracy in citing 
paffagcs From the ancient Gteei writers. 
In treating, of the efficacy of medicinal 
fimples, upon the authority of authors^ 
or indeed- in-fpeaking iif diem, greatcarfe 
(hould betaken, that. the thing recom* 
mended is not miftakcn- for fomethiiig 
tf^at may not be. poflcffed.of the fahie 
<i^Jrtues. ' » • — . - - !^ 

^' The thing of the next importance fe, 
ifo afcettain the dofc with all poffible ac- 
curacy. In both thefe' particulars I am 
apprehenfive, that Mead, in bis Efiay on 
^he M^d^ I^og, has not been fo carefill as 
%e ought ^ to have been. For, firft, ^I 
^take the • rivtr "crabs (xa^/rw hrora^ji&i) 
-**when he informs us, that O^^ re- 
" •' commends the afhes of the River 
*^ Crawfiflb; in the dofe of a good fpoon- 
" ful or two every day" not to be the 
Crawfijh^ but a i^ics of fhcH-fifh, 


CANINE Af A'DlfE^S. 2,11 

which bear much the fame refemblance 
Id Crabs» as our Crawfijb do to Lpbfters^ 
bat arc laiger. Theie are yery corxir 
aoa in the rivers of Greece^ Stcify^ ^^ad 
^^^, and, I think, in the Danube^ 

And I have the ^ more reaiba . to • be- 
lieve, that thefe. River Grab&. are meant 
Ixrth' by Diofcorides and Galen ; becaufe 
JEtiusj who almoi): repeats a great part of 
what the abovementioned authors have 
iaid, though in the title of his chapter 
he quotes Riffus and Pqfidonins^ gives to 
thefe^ crabs the epithet ^i^fAiyi^m. Now 
this, word imports ingens^ very large^ vajl^ 
an appellation by no means fuitable to 
our diminutive craw/i/h ; but which may 
with greater propriety be applied to the 
true River Crabs, if the defcription of 
them I have had from thofe that pretend 
to have ken them is jufl. 

yaniu Comarius has tranflatcd gufoyt^^y 
by magnorumf a word which I think by 
no means exprciles the meaning of tlie 

P 2 Greek 

112 A TREATISE 61^ 

Greek original ; for by the tranflatorV 
Latm word may poffibly be undcrftood, 
the largcft of a fmall fort of Rfvcf 
Crabs, when the Greek fcems to imply 
a very lafge Ipecics, 

As to the dofe, I apprehend Re xvas 
as much miftaken ; for the Grecian Co^ 
chlearion was by no means a fpoonfuli nor 
half a one. But it was much more eafy 
to call the great Cochleare^ a good fpoanfufi 
than to afcertain the exaft capacity. For 
it is fomewhat difficult to underftand 
perfcdtly thfe Grcecian mcafures, which 
were originally taken from the Pbani^ 
ciariy and afterward, in feme degree, con* 
founded with the Romany when the con** 
qu-efts of iJ-^;//^' had made the intercourfe 
with Greece more frequentv 

Besides, the different cities oi GreeCt 

had a variety in their meafures and 

weights. Thus there was the Ephtfiarif 
yUcxandriany and Attic Cotyle. .Andi 



moreover, the phyiicians, as they do now, 
ufed weights either different from the 
common fort, or divided them differently. 
Thus the great or ruftic x^l^^' Cheme, 
was one twentieth part of a Cotyle, where- 
as it was the thirtieth of the medicinal 

In general, the Attic Cochliarion was 
the tenth of the Gyathus ; 2i Cyathiis was 
the fixth of a Cotyle ; and a Cotyle half a 
Xejles, which was machthc fame as the 
Roman Sextary ; fo that a Cochliarion was 
the one hundred and twentieth part of 
an Attic Xejies. This laft was fomewhat 
lefs than a V/inchcJlcr pint, corn meafiire y 
for, according to Arhiitimot^ a Xejies 
contained in folid inches 3'3', 158. where- 
as the contents of d Winchcjier pint are 
34, ^^.. The modern fjowders, and dry 
medicines, are reckoned by weight, not 
t>y meafure. . But in Jiqilids, a fpoonful 
is a^ thirty-fecond part of a pi-nt, of pound. 
Now the contents of a Winchcjier liquid 
pint arc 28-Z-; infomuch, that a fpoonful 

P 3 is 


is but little more than a thirty-fcconfl. 
par^ of an Attic Xejies ; but a Cocbjiarion: 
is only a one hundred and twentieti^. 

But there certainly were two forts of 
Cocbliariay in common ufcj witl^ rciped: to 
which, opinions have been various. . Ri^t- 
ger is of opinion, that the Attic CocNia- 
rSon was four fcruples and two fifths of 
a.^rain ; but, according to Le Clerc^ the 
greater Cochliarion was aboUyt a, drachi^,! 
the lejQTer, a fcruple*.. 

By the pafl'age above quoted from Ga--. 
leuy it is very plain, that there were oiore 
Cpchliaria than one, from his applying to 
it the epithet 'sufjieyi^^, importiag the 
largeft. And though, as I obferved bcr 
fore, this word could not be applied to 
fo diminutive a creature as our crawfijb ; 
yet, as there were two CocJoUaria^ the 
greateft may with ftridt propriety be 
called large ( \vij.tyilks ). 


.. » , k. ■* • 

This meafure, as .woJl a$ the appellir 
don, was cgrtaiply Ukpn from the Xhell 
of a fifh j probal)ly the cockle. 

As I have never feen any of the true 
river crab^, nor been informed by any 
n^ftdern author of their having been ufeci, 
Jwft give no opinion of them from my 
pwn -experience, or thit of others. But 
;whatever opinion I may have of the au- 
thors who recommend it, I confefs, the 
whinjfical, or talifmanical ceremonies en- 
joined in the preparation of this remedy^ 
by no means recommend it to my efteem. 
I, however, believe, that it may Have 
fome efficacy in preventing the Caninp 
Madnefs, tho' none that can be much den 
pended on. This opinion is founded upon 
its being an highly alcaline fubftance 5 and 
all, or moft of the pretended fpecifics for 
this diftemper are alcaline, and deftroyers 
of acids ; as the celebrated pancake made 
of oyfter-fhells, mentioned by DeJJ'auIt ; 
jirmenian Bole ; tin, and many other. 

P 4 But 

lBut as all thefe have more frequently 
l^aited^ than been attended with fuccefi;, 
1 ihould fufpe£):» that the aihes of the 

River Crabs would have the fame fate^ 

• . . • 

for the fame reafons. 


* ' ScribdnkiS -L/^r^^ defcribes an antidote 
inade of very warm ingredients, which 
■'hfe mafief Afukins Celfus vazdi^ every 
year, and fent to Sicily^ z country much 
-irifefted Xvith mad dogs. This I (hall 
not infert here, becaufe I moft firmly be- 
lieve it poflcfied of no one virtue to re- 

G6mmend it. 

. • . > 

It appears to mc, that the Sicilians, 
purchafed it, and were fond of it, not 
•becaufe it cured any one diftemper, but 
becaufe it warmed their ftomachs, and 
by expelling flatulencies, gave them fome 
immediate relief; juft in the manner that 
fottie amohgft us cannot live comfortably 
without Fenice treacle, Mithridate, Ra- 
"leigh's confedlon, the Cardiac confeftion, 
6r gin ; all of which I efteem moft de- 



ircftablc, infamous, and dcftruftlve poir 
fons, as they arc generally ufed, and the 
Ijauft and worft legacy of Pandora. 

The fame author tells gji old woman's 
ftory of an amujet, which he purcjiafed 
at a high price, of Zopyrus, a .phyfidan, 
and ambaffador from Crete^ who learned 
it of ah old Barbarian, that was Ihip- 
Svrecked on that ifland, who ufed it there 
with great fuccefs. 

Th is was np.thing more than a piece 
of the {km of an Hyana^ tied up in a 
rag, and bound upon the left arm when 
the diftcmper was prefent; and it was 
to make the patients drink without f^ar, 
and totally cure them. 

' All that can be learned from this tale 
is, that when Scribonius Largus ^mci^aScdi 
tliis fecret, a fool and his money were 
foon parted. A dog, it feems, is faid to 
be terribly afraid of an fy^na -, therefore 
the diftemper caufed by the bite of a dog 


«)8 A- TRJt:AnFI&&)QX ? 

if. to be flighted away at therapproach o£ 
aa ^ byand^ ikin. 

« ■ » I , - ; I ■. / •. * ■ 

In a quotation above from D^ffau&p^ 
mention has been made of Palmariuss 
po\¥der. A& I have not this author hy 
me, I am obliged to take an account qf 
it from that moft excellent commenta^ 
tor on Boerhaaves aphorifms^ the Baron 
Van Swieten. According to him it is 
thus prepared. 

Take of the leaves ofRuCy Veroain^Ab^ 
leffer Sage, P/antatH, Pofypocfy, common 
Wormivood, Mint, Mugwort, Bqftard 
Baum, {MeliJJbpkyllon) Betony^ St^ Jobtis 
Wort, and the le£er Centory, each equal 
parts. All thefe were to be gathered 
every year, when in full vigour, and 
(dried betwixt papers carefully, fo as 
neither to wither too much, nor to 
contradt mouldinefs. Of all thefe pow- 
dered, half a drachm, with double the 
quantity of fugar, was to be given every 
morning falling, eating nothing af- 

ter it for three hours, in wine, cyder^ 
broth, butter, or hopey^ A drachoi^ and 
a half, or two dve^^hmh he thinks fufS^ 
cient $9 i^Ure, either ujaa oDbceft, how- 
f^^ ctmily hit. JS^t he> thinks it not 
amifs |K> g^ve dirce .or foui^ eUpccha^ iC 
the wound h^s beep, received for Sofm 
iimeg o^ the Jfydrs^J^i^i is coeao on i f(x 
fivm in this cafe he , fay^ it will perform 
ji cure . . 

.... •. ' 

He, further, adyifes to foment tho 

wound with wine, or hydromel, in which 

half a drachm of this powdef ,is p\^ 

This, he oonfefles, he had froni the jjor 

inventor,i; JacoAus i^/?w;«f(/, Lord,^:^ 

f'eyrou. ,, ., 

As I have no experience of this re-^ 
medy, I can only j(ay, that I hopp \^ 
did not, Uke Scribonius Largus, purchafe 
it at a large price i for I believe it worth 
iiothing s ^nd I have the pleafure to find 
f^im Swkfen pf the fanae opinio^. 


r . ... :* ■ ' • - - f ■• .^ , . . • . . r- . 1 ... _*TJ 

■ ■ • . • ■ 

Ui^N die con^<$rnfttiofi die towA ;W9s 
in foQs^ weeks ago> <» accoiiDt of. the 
frequency of mad <iogs» io ofd^; 4o <ui2ir 
the minds of thofe who either had been» 
or might he^ 'bit» * I publi(hed ia ibmc of 
thf^ papers an abftraifi of myinedioci.:^ 
cure* Soon after this I i^dived^ Utt^ 
'Mdthout a aame» giving a^ ztCGaMx£:% 
remedy, which, he fays, was found in ^a 
church fomc where in Lincolnfhire y whwc 
it had been regiftered, on account- of 
haying preferved almoft all thfe pariih 
from Canine Madnefs, after bites re*- 
ceived from mad dogs; and requefted 
that I would publish it in. the public 


I do not queftion the good intentions 
pfthc author, whoever he was; hut it 
was no compliment to me, to . fuppofb I 
was ignorant of the Pewter MeScine^ as 
it is comrnonly called, which was many 
years ago printed in the P^hUofopbicd 

^ranfaBionSy I think from Sir Theodore 
MayefHe\ or G'te^id i-' i^t this vv^as- the-Ve- 
ifnedy he ihforiEted vtm of,^M'leafti^k>n« 
much'thefetnfe ^ - '^ f) .;m»-^ 

- WiTtt re%(eft-to this^ pt^ffemtive, I 
ha\^e' khowii^ it cxpetkhceki ibnfto huii*^ 
dreds of times^ upolj ^brutes ; 4nd not >aB- 
frequently • upbn 'mea. Thie *e\%iit has 
been," that when it wafi^ tiniifted ta ddfte^ 
St leaft one half of the patiiehti hsiVd 
^onftraded the Canine Madnifsiariddied; 
whilft others^, under the fame cafclSim^ 
ftances, have cfcaped; Hence I diiflk -k 
reafonable to conclude, that it iis Acrt f 6«- 
tally deftitute of efficacy > but thit it fe 
not poffcffed of any virtues that ciii S6a^ 
fonahly be depended on. 

* It ftand^ thus ia t\ie'P hiJafb^hical 

■ ■' ■ ■ . • -» . . . -. 

■ • • * • '■ -.....'.■ 

Take leaves of rtfe, pictecE from' thfe 
ftalfcs and brmfedi fix oimces y -of LoMon 



aft A TREATISilB <>N > 

treacle, (or, which is better. PitmSf 
treacle) garlic, pilled; and ^bruiftd^ and 
fine filings of tin, each four ounces % pnt 
them into two quarts of canaiy,;br.good 
white wine ; or, in cafe of a nice confti* 
tution> into the fame* quantity of ftrong 
and well-worked ale, in an earthen vefi&I 
well ilopped. Then let there be made tt 
digeftion, or gentle boiling tileittof, in i 
bath heat, for fome hours^ fhutting ia th6 
fleahi. Then prefs it, and f^0am it* 
The dofe is two or three otmces, (and in 
ibme pcrfons more), to be taken every 
morning for nine dajrs* The pkrtybit* 
ten muft fafl for three hours after it | 
and the dregs that remain after expfefiiod 
muf^ be bound upon the wound received^ 
renewing it every twctity-four houfS* 

N. B^ That the ninth day after the 
bite muft not be let flip, before thi^ 
medicine be taken, lefl the poifbn feize 
the blood too flrongly. It mufl be given 
cold, or at leafl ofily a little aired. A 


C AW N1E> : M A D^ ^ S/$- «? 3 

double quantity ma/ lie; given to arbeaft 
foon after the bite. •• ^ 'r ^i m -^ 

Pliny tells a ftcry of a woman whd 
was direded in a dream to fend her 'Ibh^ 
then a foldier in iSdozw, the root of the 
pdg-rofei • called CyriorrboHonf tb take. 
She accordingly wrote to hirn; he re- 
ceived the letter juft as'he^began to dread 
water, having fome time before? been bit 
by a mad dog : he obeyed, took the re^ 
medy, and was cured; * v! ' 

* -"•..■ 

As I have never known this expericfn- 
ced, n<x ever heard of its beings u&djrl 
can giv^ no c^inion of it. But the ridi- 
culous tale above related, does not fe^m. 
to promife any great efficacy. 

► t » 

I MUST nbt omit taking notice of the 
celebrated remedy patronized by this late 
Dr. Mead^ vAx<h i» thelail edition of his 
Mechanical Account of Pinfons^ feys, thit 
^ He can fafely affirm, that he has ncjrer 
*, known this remedy to fail of fuccefs, 

^ whether 


^ whether any outward application wast 
^ ufed^ or not^ where it has been followed 
^ before the Hydrophobia came on i altho' 

< in the courfe of thirty years practice he 

< had uied it a thoufand tinges/ 

His own acount of it is as follows. 

< Let the patient be blooded at the 
^ arm, to nine or ten ounces. Take of the 
f herb called in Latin, Lichen cinereus ter-^ 

* rejirisy in EngliJJj, AJIo-coloured ground 

* Liverwort, cleaned, dried, and pow- 

* dered, half an ounce ; of black pepper 
^ powdered, two drachn>s. Mix thefe 

* well together, and divide the powder 

* into four dofes ; one of which muft be 

* taken every morning fuccefiively, ia 

* half a pint of cow's milk warm. After 

* thefc four doles are taken, the patient 
^ muft go into the cold buth, or a cold 
^ fpring, or river, every morning fafting, 
Vfor a month. He* muft be dipped- all 

* over, but not ftay in (with his head 
^ above water) longer than half a minut?. 

CAmN^'-MADNfeS^. ±i$ 

*if the water be very cold. After this 
^ he muft go in three tithes a week for a 

^ fortnight l6rtger; * ' i 

' i . ....... 

• • * 

^ This powder Was firft piibliflied iii 

' the Phtlojbphical TranfaSlionsi from Mf* 

* Dampief^ in whofe family it * had becti 

» ' ■ • 

* kept as a fecrct many years j and in thtf 

* year 1721 if was/ at my defire; put into 

* the l?barmacop. Land, by the ■ name of 

* Puhis Antilyjfus. I afterwards- made 

* this alteration only of putting two par^s 

* of Lichen to one of* pepper, inftead of 

* equal parts, becaufe I thought it too 

* hot ; and whereas but two or three 

* dofes of it were formerly given, I rc- 

* peated it four days, 

• The Lichen h a warm diuretic j th^ 

* pepper is added, I fuppofe, to make it 

* more agreeable to the ftomach; for it 
' is diftafteful and naufeous/ 


We are told, that Sir Robert Southwellt 
at the requeft of Mr. Hans SloanCi procu* 

Q red 

red the receipt: €}f4hi$^ I medicme.^^l^^ 

a kind of j€%i>'s Ear jitibui; ^tj Jl^ff^ 
Shane corrcAed this erron . 1% i^iibd to 
\^ l^QOwn by the name of hkben cinereus 
tmiejlris, Ai^i^coloured Qronn4 X^iv>?r-* 
wort i but DilkntHs h^ aew (4»i^%?d(, 
it| and called iiLicbenoides digkatHmm fh- 
^ereum^ LaSlaae foliis JinnoJU^ a^d has 


■ f 

' BoerlMve^;2JAd hi^ con^ineiitatQi^ if^ 
fS^ietertf feeon, to think tha;t qo^epep^apce 
c^ be had on this pjrQfervatjyp. Xh^ 
1^ ^d9ubt$ whether more is not iQW^ig^ It^ 
the pepper, or the jl^athingt, th^a to.^e 
AJh'Colotured Ground Liverwort \ and af** 
jQrpiSjp,,^thmjther-er ^q jnftancei^.Mrhich 
j^roY^th?^ ^ Hydrophobia. \z:^ jTilRCee^d 
fj[^v the ,i^/e of thi$. remedy y one of 
which he quotes from the Medkal Ef- 
faysy of a boy bit by a mad dog in the 
thumbs wJao tocik^ night and mornings 
ipr forty days, a drachm of this Puhis 
I :: . . Antit^i. 

Antifyffus i was plunged ten times in tJie 
fea ; ^was aftetw^c}^ cut for the ftone, 
and yet at tbcr end of nineteen, months,^ 
died of an Hydrophobia^ 

• • • 

As it will be expeftedy that I give my 
fentiments upon this^ I iha}} do it with-« 
out referve-. 

In the treatife I publiflied in theyesr 
1 74 1 > on the bite of a mad dog, I recom- 
pi?i)ded this prcjfereative, on the authori-* 
ty of Dr. Mead, having at that time had 
very little experience of it myfelf But 
I foori after le^rned^ frcJm undoubted du- 
^ority, that it had been giveft without 
fuccdfs to a gttSX number of people and 
animd^, in m^ny p^ts of the kingdom^ 
I was told, in particular, the names of 
ibur, which I d<>not at this diftance of 
time recolleft. But one livfd in the 
Tiwl;^, andther in Smithfield, tibe third at 
J/M'thampiimyiM the fourth At Bury St. 
JE^iz/f^i^, to thebqi^ pf miy i;emembrance. 

Qjj But 



But, befides the inftanccs upon rtr- 
cord, every fummer furnilhes frefli ex- 
amples, which prove this celebrated me-^ 
dicine not infallible. At the fame time. 
I have known it exhibited to many, who 
have never fincc experienced any one 
fymptom of the Canine Madnefs ; info-' 
much, that I may fay of this, as I did of 
the pewter medicine^ that though I have 
great reafon to think it not deftitute of 
virtues, yet it i& poflefled of none that 
can be fafely depended upon. 

■ i' 
There is another remedy, much ce- 
lebrated in the north of England j iot 
preventing the Canine Madnefs. It is 
prepared and difpofed of by a gentleman 
of fome rank in Lancajhire. I have 
heard it fpoken very well of by jfome.that 
have ufed it for their hounds ; who alfo 
tell me, it fucceeds very well in the hu- 
man fpecies. But as I have never feen 
it tried, I can give no opinion of it from 
my own experience, I do not, however, 




find, that it is pretended to cure the di- 
forder after the fymptoms appear. 

' ■ • • r 

■* ■ • ' ' / . - 

It would fweli this volume to an enor-^ 
xnous bulk, was I to take notice of all 
tlie ipecifics, and injudicious AntidotH 
and Theriacas^ which have in their turns 
acquired fonie reputation for preventing 
.the ^Canine Madnefs ; amohgft' which, 
the liver of the mad dog is not the leafjt 
ridiculous. I believe few, or none, have 
the leaft efficacy ; but the foundation of 
their reputation feems to be thi^. 


P;ERHAPs, out of twenty people re^r 
ported to ; have been bit by mad dogs, the 
fadt is not true with reipe(ft to two. For 
many receive a bite from a flrange dog, 
in confequonce of theii* own folly and' 
impertinence, which I think every on? 
guilty of, that teazes a dog, or endea-s- 
vours to fright him wantonly ; and on 
thefe occalions, the coiifcquence of the 
aggrefTor's imprudence is afcribed to the 
inadhefs of the dog, who immediately 

vL 3 runs 

fcjb -A Tt^fe A 1 1 fc B i d N :> 

rbhsf twsfy and is heard <of AomcimyGt 
is killed, dtfd is ceticluded td be^ftfadi 
though perhaps more rational than the 
fool that provbbKi ' kittv. ^ T^ !bme 
Specific is adminiftered ; the perfbn con* 
linites well j and the retaaidy fitqmtes the 
ittiif)ulai:ionf of having ^tW a "diflchipiri* 
that never earifted in thiit dSibjed j ^ '<rf 

^ireVeritihg^ne,'tl*at cdtil^'iievfcr te 'ftli* 
^tedl)y Aat ^ufe. -- - • --^ ■ ' ^ ' 

I :. . ■- 1 

'••' Bisii^is, dcwneftfc, or ^^porfdng ^tSogs^ 
are not tinfrcc^iiendy fbtfc, lA tofn&^tftiite 
of ibme wound, bruife, or injury, which 
rtmains covered by the Bair^ unnoticed 
by the mafter, or ih'e family ■; or they 
'niay be griped, or i?i pain from fbnfife in- 
ternal diforder, not in the leaift tending 
towards madnefs. And in all thefe cafes, 
if the miferable animal is, by handling, 
br arty other wdy hiitt, it is natural for 
fiim toHte; tiTjiorr thefe occaflon^, the 
f/oor circature is prefcipitately put to de^tth, 
tip'on 'a fuppdfition that he is mad ; and 
the injuring party (I will not fay ittjui^ed) 


CAKINE madness. i3t 

immediately applies fome Ipecific, or an- 
tidote, which acquires the credit of ' hav- 
ing prevented a difeafe, of which thcSft 
aever was the leaft danger. 

'Some few years ago I walked with i 
gentleman towards IligJbgate, by the way 
€^ Frimrofe Hill I a fpaniel-bitch follow^ 
himv ifromwhoih. her puppies Haa b^eh 
Idtely taken. -Before we got Half a; qj^ 
the' creature fell into a ftrangfef Con^nlfive 
difotxlfef, in whith fhie continued for ibiftfe 
mitmdbs y then got up, ran aSduft-SviIdly> 
ivi^ ^reat figris' 6f^ihipidity,^^4*^d ^^ 1^ 
^)H<>wed us tiofc, riot Without,remajftixj^ 
^;nsHof great difqrdtr. The Aiiktt ^fe- 
termined to kiH her inftantly, * fiippofiqg 
her mad, but I begged her life, ^s 1 
thought other wifi?; ^ 


t . ■ > 

^N the purfuit of our jourpey t^efe fits 
frequently returned, till at laft V&e jan 
laway a quarter of a mile, fat upon the 
top of a fence of carthi with great mark's 
of ftupidity and confufion ; and it was 

0^4 with 

232 A'3;JRE-AJI.6E 0N 

'y/ith much difficultyi^.aad skiWr :^ Joo^ 

time, that we could perfuadc her. to 

come back ; which at hA, ihc. did very 

aukwardly> and not feeming to know hef 

mailer. Some haymakers happened to 

]be In the fame field, one of whoa> I per- 

^uaded to put the iron of his fork betwixt 

n^r neck and a leather .cQllar ihe had on ; 

jinc} by thi$ means he lifted her up> and 

plunged h^ri as I deiiredt into an adjacent 

pond. After fwimming to land« (hefboa 

recovered her flrength, fpirit {md vnder^ 

{landing, and followed us home. . { never 

heard of her. having a fit of this kiiyl af^ 

terwar4s ; but as her mailer fooo took 

her into the country, I am not certain, 

whether ih? ever relapfed, Qr not. 

Now if this poor diilrefled animal had 
bit either her mailer or me, of which 
we were in iome danger, ^nd had. been 
immediately facrificed to our fcai;^, or 
folly, we iliould have concluded her cer- 
tainly mad ; and the antidote vve had 
taken, or th? method we had purfuq4» 



^would, without doubt, have lindefervecfl^ 
gained the reputation of preventing in us 
the Canine Madnefs. 
■• ■ ' ' ■ .'.... * - . ' 

A fpaniel, about ten months olid, at 
this tiftie in the room v^ith me, had, 
when about five moftthS did, fits, attend- 
ed with p:rong convulfiohs, great agoniies, 
and a fubfequent ftupidity for fome titne. 
I direfted my fervants to plunge him info 
cold water, and dip him oyer head "^fdr 
three or four times, for not more thajft 
tw^o or thpee feconds, the monient he was 
-feizcd with the next fit. My orders were 
obeyed; upon his being feized in the fan^^e 
manner a very few days after; and, he 
has. never had the leaft degree of the dif? 
order finge. 

Th e«e cafes, though only dogs were 
concerned, a fpecics of animals, hbwevefj 
'Whofe good qualities aiid uies recommend 
them to protedtion, efteem, and tender* 
nefs, iare of tfie more importance, as they 
fhew the imiprudence of deftroying a dog 


grj^ ?A TT RE^^A^T fST E: €/N 

ijringinad^ It wiii^ fiiniier^ teach the 
iportfmen how to cure their dogs, ibme 
of which are of great value, of die fame 
kttad''^f • diforders, wbidb; are- very fre- 
(|uttht. And they may be a^ui^d, that I 
bamj known both dogs, and tdme foxes 
IJW|uf»t}y oared Jby immeriioa in ^cold 

water; during the 'fit.. . » . 


\ J tlixsir i:y, it may ierrc ta contlboratfc 
^d^roofs. We already hatfe, of the great 
tSscv^^xJi: GoldtbitJiing in general ^ of 
^vi4e(k:h;{iam j unified in j&yi^^ I have 

the . highefl opi:nion, ^ a preiervative 
^airrfl Canine Madntfs. And though I 
itoi»e:t«ken the liberty to be- pretty frefe in 
remarking fome things that I thought cr*- 
toncous, in Mead's account of the bite of^ 
* mad dog, yet I worold by'no means dc« 
|Jriye;jhi«n of the merit of h aving.rccom*- 
iridnded frequent immerfions in jcold wa^ 
-tep* And, perhaps, the fuccefe bribed 
to • tbc . Puhis jintifyjfus ( Afh-iroioured 
^ > Ground 

Ground LTrerprort^. and peppec) inajniifp 
more juftly attributed to cold .ba^in^ 

- • * 

I = wjc L^ not protend , to : determine Jbow 
muchtnore efiedml bathing in the iolt 
mayJ he, than in cold frefli • w^ten* j rJ&lj^ 
certain^ that many that have hei^n :0lsQfift 
drowned in the fea> have ibofi after dli9i 
of the Hydrophobia \%vA I knew a? geor- 
tleman who took thirty couple of fox- 
faounds^to the fea, and had them dipped 
with all manner of caution ; nolwit^ 
Handing .which^ he loft feveral hoiii^ 
ocvery day he took. out. the packidUitt^nr 
leffe^ual means. were ufed^ t « ^i 

• • -f » f >. «-; r 

• But X have known an inftance of ;G«St- 
ccfs from bathing in fait water. Two 
large pointers were.undpwfetedly.bijt. iiy a 
mad dog. Tbekr mader diilc^ved, y f ^ 
much common &lt in? a ti^b of vf^Xps:,^ 
it would take up*; The 4ogs wece j(tir 
merfed in it fewral timesj till almi^ 
drowned* They never were $iad after 


•36 A TXlEAfTISfEr^QrN 

fkis4iicipliQe, which, thej. underwent the 
44y after the bite, as.I^emember. . . . 

As to Opium, and its preparations, 
I have never -rgiven any in doies. large 
enough to be depended upon^ as.not bcr 
lidriifg it poiTefied of any ipecLfic virtues 
ta fehf s cafe ; or any v^hich .have the leail 
tendehcy, either to prevent or cure Canine 
Madnefs. Yet I am of opinion^ that they 
may be ufed v^ ith fome advantage^ .when 
^e d^emper is actually prefent^ as they 
may poflibly moderate the fyqiptoms, 
^vifikilftmore powerful agents, perform, the 
cure ; I mean Mercurials. This* hOTver 
tor, I (peak from theory, the precarious 
Subterfuge of ignorance and inexperience. 
1 » > ■ . • , - ■« 

^ jThere is a very extraordinary, prefer- 
vattve againil the Canine Madneis, which 
though unknown in England, is believed 
leffecftual by perhaps nine tenths , of the 
Spimip nation. 'And this, as tmoft ridl^ 
culous, I mention, to (hew how eajlily 
poj>ular error is countenanced by popular 

faith I 

filith i arid With VHafffility 

of no efficacy may acquire ' urtrtiient*& 


TrtEiit' is in Spain 1 ftt of fellows^^ 

that are Called Sahidaddm^ who pfjiteria 

td cure diftcmpers pof Enjhlmds^ by st f<$ft 

6f incian tation . It i s pretended^that tfcty 

put to flight a mad dog, or even kill him; 

by looking earneftly at him i and to pjifl(i 

vent the confequerice^ of a bite, by blow Jt 

ing forcibly upon the perfon that ^l*^ 

cfeived it. They are (kid to have' the ii* 

gure of a crofs behind the tongue, ^nd tlie 

refemblance of St. Catharine^ v^httAii!^ 

the rodfs of their mouths > by the firft, 

meaning the Uvuhj and Felum Pmdukm 

Palati ; and by the fecond certain natural 

furrov^rs in the palate> which may bear 

fonic ve¥y remote refemblance to the 

Ipftkes of a i^hfeeL^ They are all great 

drunkards,'' and prel:end'> that wirte rtbt 
only enables them to blow more forcibljj, 

but alfo increafes the virtue of the blaft- 

By thiis.Edurbery th^ get a comfortaWe 



fubfiftence, being all poor» atid -of the 
Ipweft cl^fs. 

The credit given to thefe fellows would 
be more fvtrpiifingy if in all dations^ and 
^ ages» inippiitions equally ridiculous 
hid not been fupported by popular ere- 
dulife^; When the Roman enkpirc was at 
IfB fUtftmit of glory^ the Hirpue^ certBin 
£»milies amongfl the Falifci^ a people of 
Btfuria^ pi^etended to walk banefeot oa 
iMvning coalst at th« annual ikcrifiee at 
the temple oiApolh, upon Mmti%Sora£le. 
Add they were encouraged in -Ai^ hon- 
fenikal extravagance by the vn& Ranans^ 
who exempted them, on thi$ account^- 
from military fervice> and grttffed' tliem 
other privileges. 

Of this we are informed by Piiny ^ 
and yirgil alludes to it in (h« praiyer' of 
jiums to jlpoUo^ when he wanted: td df-» 
mdliih poor Cumillcu ^ •- ^ 



* -^ 


Summe DeumyfanBt culhsforaSifsi^^p$lhi * 
^em primi colimus^ cut pineus ardor acervo 
Fgfcifur^ ct mdim^freii;pietate^ perJgtiem 
CuUt^e^ Multaprefimusi Vejigiap^na. \ 

A Ttt^ dcfigBS of kn wcs> the imUlabed 
Q^ifooK AiKi.xxuri:iq)rere]ajt6d acxi^Dts ojIT, 
both, or either, have tea . frequent^ 
duped the ingenuous and undeiigning into > 
a^hdie£;af iiiiprobabilitids, nearly . bor- 
dj^«>g.>upQO tturacks; ; and perhaps iew- 
pliiji^Ab]|^ i^alculated tales^ hav^ « been fa 
4cid^uloUa^ ^$ not toiha^e impoied ^pon^ r 
at ene time <>r another, whole conimuni*^r 
ties and, nations. And I wiih our own t 
did hot adofd fb many ini)^nce$ of thii 
extravagant credulity. 

>lT'«4a «^ Ihirty years fince the kws 
agflnf^ witcbcraft:<1vepe f epeded s aodwi 


bave ftiH ibme hotic^ii^ ia fihyfic ^^ly : 
allied t6 niiagic; The race of Warlocks in 
S€OtUm^ is not y^t extind: ^ and at thi$ 

' day 

240 A TREATIS^-^Ur ^ 

day xin^ fecond Jigbt is fpoke of as no chi*- 
nuenit by many well-meaning peojde; 

In iVkr/iSrx St. Jantuftm^ blood id ex-^ 
pelted to liquify every year ; and fi>me 
few in that kingdom may ftill beLieye 
the fabulous accoimts of the Tarantula % 
though I think very few of ienfe and 
learning coniider it otherwife than as a 
vulgar error. 

The ftory is too well known to re- 
quire a detail of it in this place i though 
as this may fall into the hands of fomcji 
unacquainted with its hiftory, it is briefly 


The Tarantula i it is faid, is a large 
fpider not unfrequent in the diftri<9: of 
Taranto^ a town fituated on the gulph 
which bears its name in the ibuthermoi): 
part of Italy. This ipider is by ibme 
fabled to excite a very odd diftemper> by 
biting people in the hott;eft part of the 
fiiramer, which can only becurcd byxou^. 


.» v 

CANINE MAl>IsrESS: 141" 

1 •■ 

What made tnc dcKibt the truth 6t 
thk ftrange tak originally was, that Plinj 
\f\io lived not a great way froih this 
xmAiVty^ a«»d who ranfacked the wholo 
Worjd for ftoriee, true 6r falfc, to embel'* 
li£h ^his i»^ural hiflory^ fpeaks not on^ 
fyllaWe t(t\it tarantula. The very wdrd 
is not cbflkal ^ hence, probably, the 
thing k imports was as little heard of as 
its name. Undoubtedly, if it had exifted 
in the tinw of Plifrf^ it would not have 
tic^wpt&hi^ fe&archcs. If it fhould be 
intmiAted^ that they h^& bred there 
fiaoTy or been impiorted, 1 fboufd afk 
how P or from whence ? 

hxsf ^ gentleman of honour man/ 
yetts ag9 fatisfied mj ^bubts fully, by 
afluErmg me^. that he rdlided nine monfhd 
at Taranto; ibmie of which happened to 
be thofe in whicfa ^^e bite of thefe Ipi-^ 
ders arc reported to be moft frequent and 
araioub ; ffhat on die nxofl: diligent en- 
fiiiryv he ceuld never ftai any one that 

R had 

242 A TRfiAtlSE CN^ ^ 

had been bit by, or contracted any di-^ 
flemper from, a Tarantula ; that he bad, 
at a confiderable expence, employed peo^ 
pie ta Asai'ch after this infe<^ in th6 fieldsi 
and Gatch diem j that they brought hito 
Urge fpiders, without being able to tell 
him whether they were Tarantulas^ : oi^ 
not ; that no phyfician at Taranto^ or itt 
diftrict^ had ever ittn either one- of 
them, or a diftemper excited by the bite 5 
nor had ever known that diilernpery o* 
any other, cured by mufic > that all they 
knew of it was from tradition, of which 
they, did not believe one fyllable ; and 
that the phyfician of the moft eminence 
in the diftridt told him, the country peo-* 
pie in liarveft time frequently contracted 
a diftemper, attended with very extraor- 
dinary fymptoms, which the vulgar fome-' 
tirnes attributed to the bite of a Tarantula^ 
but, in his opinion, erroneoufly, and with-' 
gut the leaft foundation. . . 

. Another gentleman of the higheil; 
veracity, and upon whofe report I can 



depend, tells me, that when he refided 
M Naplesi being at the meetings of cer-^ 
tain gentlemen of learning and fafliion, 
who had formed themfelves into a focie** 
ty, his information from them pretty'' 
nearly correfponded with what I have 
juft rdated. 

* AGREEABLE to this is thc account 
given us by Dr. Thomas Cornelio^ in thd 
Philofophkal TranfaSiions. Abridgment^ 
Vol. III. p. 282, 286. 

* A judicious perfon, fays he, related 
^ to me, that being in the country of 

* OtrantOy where the Tarantulas are found 

* in great numbers, there was a man, 
« who thinking himfelf ftung by one of 

* them, fhewed in his neck a fmall Ipeck, 
« about which, in a very fliort time, there 

* arofe fome pimples, full of a ferous hu- 

* mour ; and that, in a few hours afteri 

* that poor man was forely afflicted with 
'^ very violent fymptoms, as Syncopes, 

* very great agitations, giddinefs of the 

R 2 * head 

-' 1 

^44 A TRRAtlSE GK ' 

• head, and vomit j but th«t vtritjiotit imf 
^JncHnation at alltodance^ g<kd without 
^ all defird of having any lauficd inflru** 

* ment, ht mi&iably died withm tWQ 
^ days, 

'The fame perfon affimx^d to niMi 

* that all thofe who think themfelves 
^bitten by Tatanfulas, {tx^ept fuch as, 

* ibr fome ends> feign thcm&lvefi to be 

* fb) are for the moft part yocing waatori 
•girls (whom the Italian writers call 

* Dolci di fale) who, by fome particular 
'^ indtfpoiition, falling into this melan<^ 

* choly madncfs, pcrfuadc themfelves, ac^ 

* cording to the vulgar prejudice, to have 
^ been ftung by a I'onmiula i and I re* 
^'member to have obferved in Qi^lakria 
ipme women, who* fei2ed on by fbtne 
^^ fuch accidents, were counted (accordiqg 
^t<i the common belief of ^t pfoviiice) 
« to be pofTeffed with th6 ^vil, 

'This bring* to my miad 4 temble 

^ evil> wiiich often enough is^b^vdi iii 

- ' c - * Calabria^ 


^ Gakbriai and is called, in their lan-r 

* guagCj Cocch Maligno. It arifeth oil 
^ the furface of the body, in the form of 

* a fmall fpcck, of the bignefs of a lupin. 
^ It caufeth fome pain, and if it grow not 


* foon red thereupon, it in a very fhort 

* time certainly kills. 

' It is the common opifiion of thofe 
' people, that fuch a diftemper befals 
^ thofe only that have eaten flelh of ani* 

* mals dead of themfelves ; which opi^ 
^ nion I can> from e^fjpcrience, affirm to 

* be falfc. 80 it frequently falls out, that 

* pf many ftrange . cfFedls we daily meet 
^ with> the true caufe not being knoWn, 

* fuch an one is affigried, which is ground- 

* ed upon fome vulgar prejudice ; and of 

* this kind I efteem to be the vulgar be- 
f iief of the caufe of that diftemperi 

* which appears in thofe that think them- 
^ fclves ilung by Tarantulas,* 

A modern author, for whofe writings 
and charaSer I have the higheft venera- 

R 3 tion. 




tion, feems, therefore to have deceived 
himfelf and others, when, in order to ren-' 
der the exiftence of Tarantulas probable, 
bo avails himfclf of arguments, which 
would be equally in favour of witchcraft, 
the Saludadores^ or any other popular de^ 

Speaking of the poor people, who 
pretend to be afFedted by the bite of this 
^ider, in order to extort alms, he fays, 

* However, though there are here many 
^ deceits and impoftures, yet thefe, I 

* think, are an evidence to prove the 

* point, fince it cannot be fuppofed, that 

* a difeafe would be counterfeited, that 
^.had never any foundation ip nature/ 

This is not quite (o ftrong as the ar- 
gument Nelfon, in his Jujiice of Peace, 
jnakes ufe of, to prove the exiftencc of 
witches. If there were no witches, there 
^vould not have been any laws againfl them^ 


CANINE: MA D N.E S'S. 247 

Innumerable are the inftanccs of people^ 
who have, by various artful, impoftures-, 
endeavoured to make the country where 
they refided believe them bewitched; 
either with an intention of cheatirtg 
compaffionate people out of money j or 
with a wOrfe defign, that of being re- 
venged on fome poor peevifh old woman, 
that had offfcndedcd them. But this 
would be a very bad argument to provfe 
the reality of witchcraft ; becaufe it may 
be fuppofed, and even afcertained, that 
this aifeftion may be counterfeited, thd" 
it never had any foundation in nature^ 

■ * ■ 

The fame author, as an evidence of 
the real exiftence of the ^arantula^ brings 
the a;uthority of Baglivi, a phyfician of 
Rome, who wrote a long diflertation oii 
this fubjed: ; and of Ludovicus Valetta^ -a' 
Celejline Monk of Apulia y who wrote a 
treatifc on this fpidef, printed at Naples 
in 1706, in which he not only anfwers 
jdic objections of thof? who deny the 

R 4 whole 


whole thing» but gives, from his own 
.knowledge, ieveral inftances of peribns 
who had fuffered in this v^zy. 

By the fame arguments Ludwicus Va^ 
J^tfa^ h^d he wrote upon magtc> might 
hjivf . proyed the common {>ra^lice of 
witchcraft in Great Britain. He migfat 
have iaid, that the Reverend Mr. GlanvHf 
St chaplain tQ the kingt wrote a book lipon 
witches, pubUihed at London, in i68 1, in 
which he not only anfwers the obje^ons 
pf thofe who deny the whole thing, bnti 
gives, from hi^ own knowledge, autbentid 
inftances of perfops who had fudcred in 
this way ; that Sinclair, a profeflbr at a 
j^riti/h univerfity, pubUthed ft tfeattfe on 
the fame fubjedt, with the feme view i 
and that King Jamfs the firft of England 
not only wrote, but publifl>ed a bock,^ 
tending to prove the reality of witchcraft, 

Catton Mat&er, a furiom Calvinift in 
^xfterif^, wrote a treatifc againll tobacco, 
mie of the principal commpdiitie$ of that 



new worlii ; and pttblUhed two vdui9it«« 
in folio of the tibials of unhappy people 
burnt for witchcraft. 

But all this may as well prove, that 
thcfc authors were miftakeit, or mifreprc-i* 
iented fads, as that the ftories they telatc 
were true. 

Gl ANVIL relates a very remarkable 
hiftory of the daughter of a fFidoiv Stiffs 
oiWelton near Daventry^ in Northamp^ 
tonjhire, that was bewitched in a very eit- 
traordinary manner, p. 263, of the edi- 
tion above quoted* He mentions one 
Mr. Robert Clari, (a fmall orthographic 
cal error for Gierke) as a kind of evidence 
of the truth of this be witchery, who, lie 
fays, was hat (hit) v^^ith -Rx^nt^ at the 

, x 

The town of Welton I know better 
than I do Bruton-Jtreefy where I ^now 
Kve J and Mr. Robert Gierke ^ here meant, 
was my mother's father, who refided at a 



village^ at the diftance of about twd 
miles. The truth of the fad is litteraUy 

: A great clamour was made in the 
country about this girl, who was faid> 
and believed to be bewitched. My 
grandfather took a great deal of pains to 
come at the bottom of the impofturc, 
and accompli/hed it ; upon which, as a 
jufticc of the peace for the county, he 
committed the. girl, and all the family, 
tQ the houfe of corredion. 


Bv what I have faid above, I may pof- 
libly incur the difpleafure of thofe old 
women, whether in petticoats or breeches^ 
that retain an implicit faith in witchcrafts 
Jf it will give them any fatisfaSion, I 
will fairly confefs, that I fincerely wifli 
there were fuch beings as witches ; be- 
caufe it would be well, if the devil Was 
more employed in playing ridiculous 
pranks, and had lefs leifure. to corrupt the 
morals of mankind* 


But alas ! the race of witches are dn 
moft extindt in England -, and in^Scot^ 
land, I am told, one fingle law has con- 
tributed a great deal to. the extirpation of 
Warlocks and Sorcereffes. It is, that in 
^ery parijQb, where one of thefe is dif-^ 
covered, the parfon, whofe duty it is to 
teach his flock better, has a heavy fine 
levied upon him. This ordinance is not 
pnly very wife, but very juft. Wife, be- 
caufe it will mofl: certainly anfwer the 
end intended; and juft, becaufe if a per- 
fon receives a falary to oppofe and battle 
jthq devil, if he has neither courage, abi- 
lity, nor fanftity fufficient to repel his in- 
folence, in the diftridt under his imme- 
diate care and infpedion, he merits a dir 
minutibn, at leafl, of that reward, to 
which a ftridler attention to his duty,- 
ftrid more faccefs, would intitle him. 

It would bean unpardonable omiffion^ 
was I in this place to negJed: offering up 
my wiflies, that the breed o£ Tarantulas, 


t5S A T;REA17I8,E iQ^ ^ 

QS ^bfi notion of tbem^ for it is ^ one^ 
ffl^vc propagated in thcfe dominions^ to 
the infinite advantage of fiddlers and bagr 
pipers^ and to the fupport of the dignity 
of phyfiCf which muft always rife in pcp!^ 
portion as it is involved in myfttry, and 
is.kifi underflood by the vulgar, \vbo csft 
liave no bufinefs to fet^ hear> belkrvtfi 
comprehend, or Judge of any one thmg 
they either feel or fufFer, unlefs ic U con« 
fiftent With the fyftem, bypothefis, or 
theory of their dodtors, 

I ttop£ this digreflion will be the moM 
readily excufed, as it tends eo banifh a 
mofl ridiculous error from the Pariieui 
of phy^c ; an error the more pernicious, 
as it has been employed to countenance a 
theory, the umA: extravagant and abfurd 
of any ever yet invented, and produ^ive 
of the moSt difmal coniequences to th« 
human fpecies : a theory, which, if not 
feafonably diicouraged, will put an end 
to the race of mankind, if not alio tx> th« 
brute cneatktni without a ddt^ or % 


C ANT N E M A D N E SIS- ^55 

conflagration; lince not 'only apotljccai- 
riesi, hilt every farrier, cow-ltecKt and 
afs doftor in England, will learnedly dii^ 
cant upon difbrdersi of the nerves, - and 
the nervous juices, and ^pply medicine^ 
accordingly. And if any phyfician of reh 
pulation, who thinks differently fr6rn- 0ie/ 
fhould call upon me to give my reafc^tf 
]^ahlkly for thefe infinuations, I ihall 
hold myfelf prepared to obey his 'Cona- 
mands, upon fufficknt notice. 

That the reader mav not have the 
trouble of turnihg over this wbol6 trea* 
tife, upon any fudden emergency^ foi* thef 
mediod I would recommend for preveiiti^ 
ing and curing CahiM- Madnejs, I iOba^t 
qpncludd with the dM^oiftion^ I gave in 
the public papers, this fummer, wh^ft 
the town was unuftiaHy alarmed by mad 


.* : I . 


.i • • * * .' 

*• ■ - • 

254? A TREATISE OJr ^ 

. • • • . • . 

« ■ . ■ ■ 


, HUB into the part where the wound ^ 
was riBceived, a dram or more of any mer-' 
cui;ial ointment^ as foon as poffible after 
tt|e bite. That made by rubbing in a 
mortar two parts of hog's lard with one 
of crude Q^ickfilver will do; but equal 
parts of hog's lard and crude Quickiilt^r 
will be better> though it requires more 
trouble to unite them ; for great care 
ihould be taken to incorporate well fhe 
Quickfilver with the lard- This fliould 
be repeated every day for a week ; but if 
it can be done twice a day witheut faliva- 
lion, it is the better. The evening of the 
fame day let the patient take the following 

TAKE of Turpeth Mineral, frpnn 
three to eight grains, according to the 
ftrength of the patient, and the degree of 
infeilion received, fo far as can be judged 
by the bite i Camphire, an .equal quan- 


tity. Let this be made with any conferve, 
as that of hips, into a bolus, or balL 
This may poflibly vomit, though the 
Camphire is added to prevent it. The 
dofe (hould be repeated the next evening 
but one ;. and again after forty-eight 
hours interval. This cannot be done 
without fome hazard of a falivation, cf-, 
pecially in fome conititutions. It muft, 
therefore, be watched, and upon the firft 
approach of any forenefs of the mouth, of 
flavering, the farther ufe of the medicine 
fhould be deferred till that ceafes, and 
then be reaflumed. 

About two or three days after the 
laft .dofe, if no accident happen as to fa- 
livation, the patient fhould bathe in cold 
water over head every day, till the day 
before the next full or new moon. And 
that day let the dofe of Turpeth Mineral 
be repeated for three times, as before ; 
but I think the dofe may then be lefs, as 
two or three grains* And after the third 
dofe let. the patient again bathe as before; 


and let this method be repeated for the 
three or four fucceeding periods of tlitt 

This is the ptefervactive noc^d &>r ibe 
hnman fpecies ; but it will fiicceed equ:fld^ 
ly with brutes, though it is impofiible tcr 
ipecify the exiiSt dofes for thexn, as fame 
are large, and others fmalU ^nd coofc^ 
quentlj require larger or fnnllcr do&s« 
In general, for a dog of a moderate fize, 6x 
or fc WQ grains of the ^urpcth Mineral arc 


But when any fymptoms of the di- 
ilaetnpef begin to appear, fomebody of flkill 
fhould attend i for then the qure diepend^^ 
upon fkturating the body, as much as pof- 
fibic, with Mercory, without raifrng a fa**' 
livation precipitatdy, or fo as to mjure tlw 
patient. Therefore more Mercury {houli 
be robbed in,, and ni:arc frcqaen* dofes <rf* 
the T^urptth Mineral flwdd. he exhibited,, 
as not a moment mufl heldl. Whea ^is 


• 1 



method Is purfued, no heating medicines 
fhould be given on any account. Nervous 
medicines^ therefore, which in general^ 
excite lfeat> are to be carefully avoided. 
As yet no inftance has come to my know- 
ledge of a cure performed by any of the 
preparations of Opium> nor by Mufk 
Without Mercury. 

The Tonquin remedy, mentioned above, 
is in confiderable reputation, and I have 
reafbn to believe, not without dcferving it, 
in fome meafure. The ufe of it, which I 
would recommend, is (after the preferva- 
tive method has been duly purfued) to take 
twenty-five grains of the Native Cinnabari 
twenty-five grains of Factitious Cinnabar, 
and fourteen jgrains of the beft Mufk, in a 
glafs of arrack, the night before feveral of 
the fucceeding great periods of thfe moon. 




TTTHEN thefe fheets were very 
V V ^^^^ printed off, it had not oc- 
curred to me, that M. T^awvry^ in the 
Htjioire de l' Academie Royal des Science^^ 
gives a hint, that Mercury might pofiibly 
be ufeful in the cure of Canine Madnejs. 
He firft gives the diffedion of a perion 
who died of this diftemper j and, from 
the appearances, deduces a very indiffe- 
rent theory. , But he fays afterwards, that 
this patient found great relief after vo- 
miting plentifully ; and that probably 
emetics would facilitate the cure, if they 
could be retained long in the ftomachi 
He adds. Pent etre le Mercure en grande 
quantity forceroit il les Objiacles que le Re^ 
Jerrement des Veines apporte a la Circur^ 
latkn. Perhaps Mercury in a great quanL> 
tity might break through the obftacle^ 
which the [contraftion of the veins op- 
• pcfes to the circulation. 

As I have laid claim to the merit of this 
difcovcry, I am pleafed that I faw this foon 
enough to anticipate any future cavils. 


C A NI N E- M A D ISTE S S. 259 

As to my own theory, which induced 
me to try Mercury in this diftemper, J 
have no great reafon to boaft of it y be- 
caufe, like moft others, it was erroneous 
and falfe. For I apprehended, that the 
foam difcharged in large quantities from 
the mouths of animals labouring under 
Canine Madnefs, being replete with very 
poifonous and aftive falts, nature (or 
whatever that mav be called, which en* 
deayours to expel what is ofFenfive to its 
own ceconomy) was attempting a crifis by 
the falivary glands ; but failed of that fa- 
lutary end, becaufe the extremely corro- 
five poifon, inflaming the Fauces^ Oefo-^ 
pbagusy and ftomach, excited a gangrene^ 
before it trould be accompliflied. It 
feemed, 'therefore, reafonable to believci 
that this poifon might pafs oiFinofFen- 
fively, provided it was diluted with a 
greater quantity of Saliva^ which copious 
dofes of Mercury feldom fail to throw 
upon the glands of the Fauces. But when 
I found Mercury cured the diftemper^f 
either with, or without a falivation, the 
futility of my Hypothefis was evident; 
though, I confcfs, in the cure of an aftudl 
Hydropbobia^l hz6, rather find the Mer^ 
^ury falivate, than otherwife. 

S 2 I 


I FIND, alfo, I have omitted to men- 
tion, that Mr. Darlue^ a phyfician of Cail^ 
ian iii Provence, in the years 1747 and 
1748, either prevented or cured the Ca-* 
nine Madnefs in many patients, one of 
which was himfelf, by Turpetb Mineral. 
But of this I have no particulars, all that 
I* know, being from the French editor's 
preface to Frere du CtrnfeV^ pjipers. 

I REMEMBER, fome time ago, to have 
read, either in a news-paper or a Maga- 
zine, fomething very arch and quaint, 
jtbout a young ftiUow at EdinBurgb, who 
died of an Hydrophobia, after having taken 
Calomel, for the cure of a venereal com- 
plaint, by way of objeftion to my method 
of cure. 

Dr. Andrew Flummery in the fixtb vo- 
lume of the Medical EJfays, relates the 
cafe of a rakifti young fellow, as it ap- 
pears/ who died oi zxi Hydrophobia, at- 
tended' with very terrible circumftances. 
The dodlors were told^ by a companion 
of this young man, that at the time he 
received the bite, he had been taking Ca-- 
hnelfor the c\ivc-6fz Gonorrhoea % but in 
ia mamiermor* likely to do him iojury, 
* than 


than fervice. But it by no means appears, 
that he took any Calomel after the receipt 
of the bite. Be that as it may, the cafe 
abovementioned in fo irregular a fubjcft, 
is of no great cohfequcnce as an objeiflion 
to the doilrine I have endeavoured to 
fupport, by fuch a multitude of evidences. 

The difficulty of giving the mad dog 
a dofe of Turpeth Miner al, I find, has 
been objeAed by fome as an infuperable 
obftacle to the method of cure I recom- 
mend 5 but there is nothing more eafy. 
Two pair oi couples, or one collar with 
two pair of chains to it, will readily fix a 
dog's head in fuch a portion, as to make 
it impoffible for him to turn and bite 5 
then compreffing the /kin of his neck, 
with one hand, to make him open his 
mouth, a ball fixed to the end of a thin 
hazle ftick, or whale-bone, is thruft down 
his throat without any difficulty, 

SiN€£ the preceding flieets were print- 
ed, fever^l of my friends, who have pc* 
rufed them, feem to be of opinion, that 
the bathing in cold water, after the courfc 
of Mercurials I have enjoyned, is an un- 
neceflary feverity, and fuperfluous; becaufc 
they havq themfelvss prevented the Hy^ 



irophobia by the Mercury^ without any 
bathing at all. For example, a young 
man in St. James's market was bit by a 
mad dog in St. James s Park, about five 
years ago. He took and applied the Mer- 
cury, as directed ; is now grown a man, 
and has never had the leaft fymptom of 
Canine Madnefs ; and this without ever 

All I can f^v to this is, that I have 
always advifed bathing, both for men and 
rfbgs, by way of prevention, and was 
unwilling to drop any part of the me- 
thod ^ that has been attended with fuch 
conflfanl fucccfs. But as Mercury has 
aiways cured the Canine Madnefs, after 
the appearance of the fymptoms, without 
ahy bathkigt this makes it probable it 
might, alfo, prevent it, without the ufc 
of Cold water. 

I FORGOT to take notice above, that I 
look upon the aftion of vomiting to be 
^extremely falutary, when the fymptoms 
have begun to manifeft themfelves, as it 
difchiarges from the ftomach the acrid 
and poifonous bile. Camphire, therefore, 
ih this' cafe, (bould not be added to the 



Turpetb Mineral y at leaft, till the ftomach 
has difcharged itfelf fufficiently. 

I HAVE frequently above taken notipe 
of a fpecies of inftinft in dogs, which di- 
rects them to avoid all intercourfe with 
one of the fame fpecies, that is mad. Of 
this the following inftance amounts to a 
full proof. 

A nobleman, who does every thing 
with an adroitnefs, that generally refults. 
from a good underftanding, was one day 
laft fummer informed, that a ftrange mad 
dog in fiis park had bit fome of his dogs, 
and that his keepers were endeavouring to 
fhoot him. This he forbid, and diredied 
that they fhould catch him in a net., 
This was put in execution ; the dog was 
confined, io as to render it impoffible for 
him to do any mifchief, till he died ex- 
tremely raving. 

Mean time, he ordered a cur dog to 
be procured at the neighbouring village, 
who was confined three days without 
foody having only water allowed him* 
Then a piece of roafted veal was rubbed on 
the mouth of the dead mad dog, and offer 'd 
to the half-famifhed cur. This he would 


264 A TREATISE, C^c. 

not touch, but avoided it with figDs o£ 
the utmoft confternation. Another bit 
of the fame veal, w^hich had not been 
near the mad dog, was immediately after 
offered him, and he cat it very greedily. 

About fixtcen years ago, I gave a gen- 
tleman the pamphlet I had fome few 
years before publiflied, upon the bite of a 
mad dog. He had very foon after an oc* 
cafion of putting in practice the method 
I there recommended, and related to m© 
the particulars of the cafe. This I did 
not recoiled: foon enough to infert in rts^ 
proper place ; but meeting him two daysr 
ago, he put me in mind of it, and I Judged 
it proper to infert it here, particularly a^ 
wounds in the face and head, artj cflcem- 
ed the moft dangerous. 

A man at Leatherbeadf I think a black- 
fmkh, had a piece tora out of bis cheek 
by a dog indifputably mad. The wound 
had a very bad appearance, and a large tu- 
mor arofe. He took Turpefh Minerals 
The wound foon difcharged a Uack mat- 
ter, in large quantities : the tumor fuh-' 
fided; the wound healed, and he has 
continued well ever fince.