HEALTH SCIENCES LIBRARY
UNIVERSITY OF MARYLAND
BALTIMORE
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BULLETIN
School of Medicine
University of Maryland
Volume 51, 1966
)>
xH
HEALTH SCIENCES LIBRARY
UNIVERSITY OF MARYLAND
PA' TIMORF
i~>l-D^2^
Abdullah. J.. M.B.. page 43
Anccs, Isadorc C, M.D.. page 17
Benign Localized Fibrous Mesothelioma
of Pleura, page 2 1
Bereston. Eugene S.. M.D.. page 53
Book Reviews:
A University is Born by Margaret
Byrnside Ballard, M.D. Reviewed
by John E. Sa\age. M.D.. page 59
Basic Gcisiro-Enteroloi>y by J. M. Naish
and A. E. Read. Reviewed by J. W.
Eckholdt. M.D.. page 58
Conlroversy in Internal Medicine edited
by Franz J. Ingelfinger, M.D.,
Arnold S. Reiman, M.D., and Max-
well Finland. M.D., page 58
Diseases of the Newborn by Alexander
J. Schaffer. M.D.. and Milton Mar-
kowitz. M.D. Reviewed by Donald
E. Knickerbocker, M.D., page 34
Ferment in Medicine. A Study of the
Essence of Medical Practice and of
Its New Dilemmas by Richard M.
Magraw, M.D., and Daniel B.
Magraw. M.B.A. Reviewed by
Mitchell J. Rosenholtz. M.D.. page
60
Gonadotropins: Physiochemical and
Immunologic Properties edited by
G. E. W. Wolstenholme and Julia
Knight. Reviewed by Arthur L.
Haskins. M.D.. page 58
Obstetrics by J. P. Greenhill. Reviewed
by Norman Levin, page 33
Chloramphenicol Treatment of Pyogenic
Meningitis, page 43
Chromosomal Mosaicism in Gonadal Dys-
genesis — Report of a Case, pages 12,
28
Clark. Howard, page 3
Correlative Study of Chronic Arterial
Hypertension and Pregnancy, page 17
Volume .")1. 19()6
Cowley. R. A.. M.D.. page 36
Dialung Artificial Kidney — A Compact.
Pumpless, Low Cost, Hand Portable,
Clinical Hemodialysis System, page 3
Esmond. William G.. M.D., page 3
Ferris, C. D., D.Sc, page 36
Frequency and Power Considerations in
the Use of Alternating Current Defibril-
lators, page 36
Gallager. L. R.. M.D.. page 43
Glick, Samuel S., page 53
Haskins, Arthur, M.D., page 17
Hassan, S., M.B., page 43
Hornick. R. B., M.D., page 43
Khan. I.. M.B.. page 43
Khan. M. A., M.B., page 43
Lewitinn, Albert, page 3
Messer, J., Ph.D.. page 43
Millett. Joseph, M.D., page 21
Moore, Sarah, page 3
Moore, T. W., M.S., page 36
Moszkowski, Erica F.. M.D., pages 12, 28
Robinson. Harry M., Jr., M.D., page 39
Ronald. A. R., M.D., page 43
Shafti. M. J.. M.B., page 43
Strauch, Manfred, M.D., page 3
Taubert, Hans-Dieter, M.D., pages 12, 28
Tolnaftate, Specific Antifungal Agent,
page 39
Toxic Epidermal Necrolysis, Report of a
Case, page 53
Woodward, T. £., M.D.. page 43
Zaheer Ud-Din. M.B., page 43
October. 1966
.xliii
BULLETIN School of Medicine
UnwersUtj of Mar/jJond
VOLUME 51 JANUARY, 1966 NUMBER 1
TABLE OF CONTENTS
ORIGINAL ARTICLES
The Dialung Artificial Kidney — A Compoct, Pumpless, Low Cost,
Hand Portoble, Clinical Hemodialysis System
William G. Esmond, M.D., et.al.
Chromosomal Mosaicism in Gonadal Dysgenesis — Report of a Case-
Hans-Dicler Taubert, M.D., Erica F. Moszkowski, M.D.
MEDICAL SCHOOL SECTION
Dean's Letter
Reorganization of School Administrotio
Dr. Bradley Retires os Pediatric Head
Faculty Notes
Los Amigos de Cajol Dedicate Memorial Bust at Petlllo
ALUMNI ASSOCIATION SECTION
President's Letter
Treasurer's Report of the Medical Alumni Association xii
Abstract of Minutes of Boord of Directors Xiii
U. of M. Alumni At Annual Meeting, Southern Medical Association XV
Alumni Day, May 6, 1966 _ Xvi
Anniversary Reunion Class Captains xviii
Closs Of 1916 — 50th Anniversary Xviii
Class Of 1921 — 45th Anniversary xix
Class Of 1926 — 40th Anniversary XX
Class OF 1931 — 35th Anniversary xxi
Class Of 1936 — 30th Anniversary xxii
Class Of 1941 — 25th Anniversary . xxiv
Class Of 1946 — 20th Anniversary xxvii
Class Of 1951 — 15th Anniversary xxix
Class Of 1956 — 10th Anniversary xxxi
Class Of 1961 — 5th Anniversary xxxiv
Roster of Senior Alumni xxxvi
January, 1966
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BULLETIN School of Medicine
Universitij of Maryland
VOLUME 51
JANUARY, 1966
NUMBER 1
The Dialung Artificial Kidney -A Compact,
Piiinpless, Low Cost, Hand Portable, Clinical
Hemodialysis System
WILLIAM G. ESMOND, M.D., MANFRED STRAUCH, M.D., HOWARD CLARK,
ALBERT LEWITINN, SARAH MOORE
A NUMBER of successful artificial
kidney systems^ have been produced and
are being employed clinically.^' 3, 4, 6, 6
Some systems require pumps^ for both
blood and dialysis solution and others
have been designed for low flow resistance
and can be used without pumps. ^' ^- ^
All systems designed to date are expensive
to purchase and to operate. Since the con-
vincing demonstrations of E>r. Belding
Scribner that maintainance of life in
chronic renal failure is possible with
hemodialysis carried out two or three
times a weekj' ^- s. lo the fundamental
problem to be solved has been the tre-
mendous cost required to maintain a
patient in reasonably good health by this
technique. This cost which was initially
approximately $20,000 per patient per
year has been progressively lowered until
at the present time is about $5,000 to
$7,500 per year per patient. Funda-
From departments of medicine and surgery
(Division of Thoracic Surgery), University of
Maryland School of Medicine, Redwood and
Greene Streets, Baltimore 1, Maryland
Supported principally by N.I.H. grant HE-
02618-01-09 and in part by a grant from the
Surgeon General, U. S. Army DA 49-193-MD-
2229.
mentally, the primary engineering prob-
lem to be solved in hemodialysis is to de-
sign a system which will produce the
greatest mass transfer of waste products
from a patient's blood to the dialysis bath
for the least monetary expense including
all factors. The optimum artificial kidney
system designed for this purpose will have
the following design parameters ^^^
1 . Low flow resistance so that a maxi-
mum of available blood flow may occur
through the device by blood pressure
alone.
2. Low priming volimie which is as
constant as possible to avoid the need for
priming blood. All but a few drops of
blood should be recoverable from the
device at the termination of hemodialysis.
3. Ultra filtration should be possible
if desired.
4. The flow distribution of blood and
rinsing solution should be equalized so
that all areas of the dialysis membrane
work efficiently and no shimting should
occur.
5. Mass transfer should be maximized
by controlling fluid film boundary layers
and by using a sufficient surface area of
the most permeable membrane attainable.
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
6. The device should possess smooth
non-toxic surfaces and be biochemically
compatible with blood. Red cell hemoly-
sis, and white cell and platelet destruction
should be as low as possible.
7. The device should be constructed
of low cost parts and be disposable or be
easily recleaned and autoclaved.
8. Various sizes of the device should
be available for infant, pediatric and
adult use.
9. The device should be steam auto-
clavable or be sterilizable with ethylene
oxide gas.
10. The device should be safe in
operation and be leak free in use after
suitable assembly tests.
1 1 . The auxiliary apparatus used with
the dialyzer should be simple, inexpensive
and easily maintained.
12. The system should be so simple
and safe that it may be monitored by
the patient himself or by a member of the
family.
The optimization of any design is
usually a continuing process and often
lags due to the non-availability of essential
1 '\ r f
*»<-.
t^sffi^
Fie.
[. standard one square meter 65 plats Dialane.
Aoministration sets and prepunched Bemberg PT
150 cuprophane membranes are shown in the fore-
ground. The 4 long alignment pins and 8 long
clamping studs are used in the rare event that a 2
square meter dialyzer may be required for a difficulty
dializable toxin.
materials only to surge ahead after an
advance in technology occurs in another
field making new materials or techniques
available. The Dialung artificial kidney
(Figure 1) was originally designed by the
author in 1956 as a multiple, parallel
path, pumpless, autoclavable hemodia-
lyzer. Initial models made in 1957 with
Nylon injection molded plates (Figure 2)
Fig. 2. Original design Dialung plate. Eight mani-
fold channels are provided to allow both cross flow
and counter current flow stacking. Only 4 mani-
folds arc used at 1 time. The 2 dual fluid admittance
and discharge ports, clear internal distribution chan-
nels and the 84 dialysis grid grooves on each side
of the 12.5 X 12.5 mm. central area for dialysis
are shown. The original materia! was Nylon and
was later changed to polypropylene.
functioned well but were difiicult to
sterilize by autoclaving without excessive
distortion. The Nylon plates could be
used only one time. The advent of auto-
clavable polypropylene plastic and a re-
design of the molded plate (Figure 3) to
confer greater dimensional stabiUty re-
sulted in a multi-parallel plate hemodia-
lyzer (Dialung) with efficient function
meeting the foregoing design para-
meters. i^
The basic inexpensive Dialung plate
is precision injection molded in polypropy-
lene plastic and possesses a glossy smooth
surface completely compatible with blood.
The plates measure 1.6 mm. thick and
are 203 mm. square. Eight circular fluid
Vol. 51. No. 1
ESMOND, STRAUCH, CLARK. LEIVITINN. MOORE— DIALUNG
Fig:. 3. The redesigned Dialan? plate is pi
The slot type manifolds have been eliminati
appear as circular holes in 8 "ears" on the <
of the plate. This plate molded in polypropyle
been found to be dimensionally stable in
use usinff steam autoclave sterilization.
manifolds are present on the edges of
the plate. One manifold is used to intro-
duce (heparinized) blood and one to
drain dialyzed blood. Blood descends in
the entrance manifold and passes into
each blood plate through two pairs of
small metering ports 0.8 mm. square and
6 mm. in length. The blood then flows
in a clear distribution groove the length
of the plate and crosses both sides of
the central grid of the plates in 84 grooves
to a second collecting channel and then
flows to a second dual pair of metering
ports which allows the blood to leave
the plate into a discharge manifold where
it flows out of the bottom of the kidney.
In use, the blood plates are alternated
with Bemberg PT 150 cuprophane cellu-
PUHIFIEO BLOOD OUT DIALYSIS FLUID IN
DIALYSIS FLUID IN
u-t- ♦.
WASTE a DIALYSIS FLUID OUT
Fie- 4. Counter carrent Dialnns stacking patte
January, 1966
nd pampless simple arrangement for hemodialysis.
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
CROSS FLOW DIALUN6
ASSEMBLY DIAGRAM
MEMBRANE
CLAMPING
PLATE
RINSING BLOOD BLOOD RINSING
SOL IN IN OUT SOL OUT
Fig. 5. Cross flow Dialung stacking pattern.
lose membranes and dialysis solution
rinsing fluid plates in either a counter
current flow pattern (Figure 4) or in a
cross flow path pattern (Figure 5). The
plates are clamped securely between
1.4 X 20.5 X 20.5 cm. electropolished
stainless steel clamping plates which pro-
vide an effective sealing pressure by
means of eight stainless steel studs,
washers, and nuts. The device is leak-
proof and will withstand a pressure test
of 2,600 mm. Hg. with duPont PD 250
cellophane membranes and 1,000 mm.
Hg. with Bemberg PT 150 cuprophane
membranes. The priming volume for a
one square meter surface area Dialung
having 65 plates and 66 membranes is
200 ml. for the blood compartment and
200 ml. for the dialysis fluid compartment
so that no blood need be used in prim-
ing. At the termination of hemodialysis
practically all blood can be drained back
to the patient. Blood flow resistance is
quite low and in a standard one square
meter dialyzer, a blood pressure of 70
mm. Hg. at the inlet of the device will
cause a blood flow of 200 ml. per minute.
Blood flows without a pump, in clinical
practice, have ranged from 90 ml. /minute
to 500 ml. per minute. Hemolysis has
not been detectable in clinical use. An
ultra filtrate of 100 ml. /hour can be ob-
tained with one square meter of Bemberg
PT 150 cuprophane membranes for each
100 mm. Hg. pressure difference. Ultra
filtration can be greatly enhanced by rais-
ing glucose concentration in the dialysis
bath to 1,000-1,200 mg.%
The modular construction employed in
the Dialung allows the clinician to as-
semble a small dialyzer for infants (0.24
M^) or larger dialyzers for children (0.48
Vol. 51. No. 1
ESMOND, STRAUCH. CLARK, LFJVITINN. MOORE— DIALUNG
Fig. 7. Lightweigrht portable version of the Dialnng d
dialyzer with potential applications in home hemodialysi
practice. Light weight, low cost, injection molded )
the stainless steel plates shown. Tube fittings are lo
cost and further simplify use. A one gallon hemodial
diluted with 35 parts of water to make up a 128 liter
a collapsible 150 liter canvas dialysis tank (not sho
than 50
M2) or adults (1 M^) (Figure 6). A
lightweight, "disposable" model of the
Dialung constructed for potential appli-
cation in military medicine is shown in
Figure 7. Molds for lightweight, glass
filled Lexan clamping plates which will
lower the weight and cost of the dis-
posable version of the Dialung are now
being constructed.
Flow distribution is optimized in the
Dialung by a member of procedures.
Blood is caused to enter the top of the
unit and discharges from the opposite
side of the bottom of the unit. In ad-
dition, the blood (or fluid) ports of each
veloped as a simplified, pressembled, one use, disposable
and in military hemodialysis as well as in hospital
lass filled rigid Lexan clamping plates will soon replace
w cost, press in, injection molded Nylon which decrease
rsis fluid concentrate is shown which can be quickly
hemodialysis bath. All components shown including
n-n) can be packed in a small suitcase weighing less
pounds.
plate are arranged on opposite comers
to equalize resistance. In general, it has
been found that cross flow stacking re-
sults in an exact fixed even resistance
geometry whereas the counter current
stacking arrangement with parallel plates^^
allows some variable "nesting" of the
grids to occur in each other resulting
in some uneven flow patterns. We have
advised all users of the present model
Dialung to employ cross flow stacking.
Recent mathematical studies have indi-
cated no real theoretical advantage in
counter current flow as was previously
believed. 11
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
250r
UREA DIALYSANCE
CREATININE DIALYSANCE
--DUPONT PD-215
eEMBERG PT-150
SSPONIFIED CELLULOSE
aCETJTE
100 200 300 400 500 600 700 800
IMULATED BLOOD FLOW RATE cc/MINUTE
Fig. 6. In vitro urea dialysance carves of a 2
square meter Dialung. Chemically modified cellulose
acetate dialysis membranes offer great promise of
producing more permeable kidney membranes and
are the subject of additional research.
250
CHLORIDE DIALYSANCE
200
^^---:_...
150
x:^-'''-
100
//''•'' DUPONT PD-215
A*''' BEM8EBG PT-150
50
AV SJPONIFIED CELLULOSE
" ^/ (SCET/ITE
L. 1 1 1 1 1. ] 1 1
100 200 300 400 500 600 700 800
SIMULATED BLOOD FLOW RATE cc/MINUTE
In vitro studies indicate excellent clear-
ance of urea, creainine, and chlorides
(Figures 8, 9, 10). These figures indi-
cate performance using the highest bath
flow rates attainable. Clinical usage re-
sults in lower bath flow rates by simple
syphon from an elevated plastic tank in
a one pass pumpless flow to drain" of
from 500 to 1,500 ml./min. and dialys-
ance figures are slightly reduced by this
lower bath flow rate. Data obtained in
clinical dialyses for a one square meter
Dialung have indicated a clearance
for urea of from 60-75 ml./min. and
from 35-45 ml. of creatinine per minute.
These figures are limited of course by the
DUPONT PD-215
BEMBERG PT-150
S4P0NIFIED CELLULOSE
100 200 300 400 500 600 700
SIMULATED BLOOD FLOW RATE Cc/MINU
volume of blood obtainable from the
small forearm arteries of patients in a
pumpless system. The equipment used
to mix and heat dialysis solution is shown
in Figure 11.
Fie. 11. 400 liter stainless steel dialysis solution
concentrate preparation tank for tlie Dialung. The
inexpensive 200 liter polyethylene plastic tank may
be used with prepared dialysis solution concentrate
and city water to provide an inexpensive supply of
dialysis rinsing solution in a pumpless one pass flow
through the Dialung to the drain.
In order to obtain the optimum mem-
brane for the hemodialyzer, a rotating
cell was designed in which 50 ml. of
saline and 50 ml. of water can be placed
on each side of each vertically mounted
test membrane (Figure 12). The cell was
then rotated at 180 r.p.m. effectively
scouring the membrane and practically
eliminating the usual stagnant fluid film
Vol. 51, No. 1
ESMOND, STRAUCH. CLARK, LEWITINN. MOORE— DIALUNG
Fig. 12. Dual chamber rotating dialysis test cell with vertical membrane support.
boundary at the interface. Periodic
chloride analyses in the Buchler-Cotlove
chloridimeter then allowed construction
of a curve the slope of which indicates the
absolute permeability of the membrane
to chloride (Figure 13). Since chloride
and urea permeabilities in cellulose films
are quite close, the relative permeabilities
to chloride were then used to rate the
membranes. The test results obtained
in this original technique are shown in
Figure 14. Bemberg PT 150 cuprophane
0.6 mil. thick was found superior to other
available membranes and is the mem-
brane of choice in current cUnical practice.
Clinical applications of the Dialung
Fig. 13. Typical carves obtained from chloride
analyses of a solution in rotating dialysis cell.
Original formula gives precise quantities of chloride
passing through a unit area of membrane in 1
second for a driving concentration difference of one
milli eqaivalent/L of chloride ion.
have included a patient with Doriden
poisoning successfully treated in a 16
Dta^is in standard jymetrical
rototing dialysis cell with
vertical membran
MEO/l
/- „ p- b,
l\^-^.^
11 / ■- " -z^
1 «so/s^«.o ..«/«>™»*,, ™^^
C j^ _ B^^^
1
\^'{\lo'^.)
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
MEMBRANE PERMEABILITY STUDIES
Test
Cell Perm
Perm
MEMBRANE
Na ClxlO-3
PSPXlO-3
Vi-A Unsoftened*
42
5.0
1/2-B 15% S-1*
45
8
1/2 -C 20% S-1*
46
10
Vi-G 20% S-12A*
47
8
Va Unsoftened*
32
6.2
%-B 15% S-1*
38
7.3
y4-E20% 2-2A*
32
6.2
Bemberg .0006"
94
15
Dupont .002"
57x10-3
8
Dupont .002"
(No Rotation)
6x10-3
M2
Membrane Area == 62 cm2
in Rotating Test Call
Test Cell Permeability = meg/ meg . Second
To Convert to .(„„ . t i,pr«
Absolute = Meg 'Liters „, Mult. by .0787
Permeability Mei ' Second • M2
Fig. 14
HH 2 54 rRS GLUTErHIMIDE POISONING HEM0DI4LVSIS
ADMISSION
ABTEBIAL PRESSURE
FLUID BALANCE
+ 709 m
URINARr OUTPUT
1 .
P 1
8 \2 16 20
HOURS AFTER ADMISSION
Fig. 15 Graohical clinical recnrd of a patient
dialyzed with the Dialung for acute Glutethimide
(Doriden) poisoning after swallowing 24 half gram
tablets of Doriden and several "Nods" sleeping cap-
BUN
MGV.
100-
ATW j2eYRS BICHLORIDE OF MERCURY POISONING
DOSE- 5 GRAMS TAKEN
IMMEDIATEir BEFORE
OMISSION
DISCHflflGED IO/3f/G5
SAL 175 Mj ™ BAL 2 5 Mj '/./Kj CREATI
5 150
HOSPITAL DAY
Fig. 16. Graphical clinical record of a young patient
who sustained acute renal failure after ingestion of
bichloride of mercury. Dialung dialysis on the
seventh hospital dav resulted in marked biochemical
as well as clinical improvement. Spontaneous diuresis
beginning on the 9th hospital day eliminated the
need for further dialysis. Recovery was complete.
hour hemodialysis^^ (Figure 15), a
patient with renal failure secondary to
acute bichloride of mercury poisoning
successfully treated in a single 20 hour
hemodialysis after which renal function
gradually returned, a patient with bro-
mide poisoning successfully treated in
three 6 hour dialyses and number of
patients with renal failure due to shock,
methanol intoxication and crushing
injuries who were also successfully treated.
Summary
The design parameters for an optimized
artificial kidney system have been pre-
sented together with a new compact,
pumpless, clinical hemodialyzer ( Dia-
lung) that meets desired optimization
parameters in clinical practice. This dia-
lyzer can be employed to further lower
the cost of, and to increase the safety
and efficiency of hemodialysis.
10
Vol. 51, No. 1
ESMOND, STRAUCFI, CLARK, LEWITIKN, MOORE— DIALUNG
Addendum
Since the preparation of this paper 5 addi-
tional patients have been accepted for long
term twice a week hemodialysis. In the case of
one 37-year-old man, who was a computer
operator for the Social Security Administration,
and whose wife is a nurse, the entire simple
hemodialysis procedure is now being carried
on at home without physician intervention. Cost
analysis figures indicate that the Dialung system
for home chronic twice a week hemodialysis
can be operated for a total cost for equipment
and supplies for one year for from between
$1500 and $1800 a year.
This simplified, low cost system opens a new
therapeutic horizon to the 100,000 patients
succumbing to renal disease in the United States
each year. The Public Health Services esti-
mates that from 10,000 to 20,000 of the pa-
tients can be maintained in reasonably good
health by twice a week hemodialysis. Only
350 patients are now being treated twice a
week by other hemodialysis techniques because
of the high cost of operation of other artificial
kidneys. The Dialung is simple enough to be
used by a housewife and can obviously be
applied by every physician in general practice.
References
1. Abel. J. J., Rountree, L. G., and Turner,
B. B.; Removal of Diffusible Substances by
Dialysis. /. Pharmacol Exp Ther 5:275, 1914.
2. KoLFF, W. J., and Watschinger, B.;
Further Development of a Coil Kidney, Dis-
posable Artificial Kidney. J Lab Clin Med
47:969, 1956.
3. Alwall, N.; On the Artificial Kidney.
I. Apparatus for Dialysis of the Blood in Vivo.
Acta Med Scan 128:211, 1947.
4. Skeggs, L. T., Jr., Leonards, J. R., and
Heisler, C. R.; Artificial Kidney 11. Con-
struction and Operation of an Improved Con-
tinuous Dialyzer. Proc Soc Exp Biol Med
72:539, 1949
5. MacNeill. A. E.; Technic with Paral-
lel Flow, Straight Tube Blood Dialyzer. New
York J Med 59:\4, 1959.
6. KiiL, F.; Development of a Parallel Flow,
Artificial Kidney in Plastics. Acta Clin Scand
f.Si,ppl)25.^:\43. I960.
7. Scribner. B. H., Buri, R., Caner, J. E. Z.,
Hegstrom, R., and Burnell, J. M.; The
Treatment of Chronic Uremia by Means of
Intermittent Hemodialysis: A Preliminary Re-
port, Trans Amer Soc Art hit Org 6.114, 1960.
8. QuiNTON. W., DiLLARD, D., and Scribner,
B. H.; Cannulation of Blood Vessels for Pro-
longed Hemodialysis, Trans Amer Soc Art Int
Org 6 :W-i. 1960.
9. Hegstrom, R. M., Murray, J. S.,
Pendras, J. P., Burnell, J. M., and Scribner,
B. S.; Two Years Experience with Periodic
Hemodialysis in Treatment of Chronic Uremia,
Trans Amer Soc Art Int Org 8:266, 1962.
10. Murray, J. S., Pendras, J. P., Lind-
HOLM, D. D., and Erickson, R. V.; Twenty-
Five Months Experience in the Treatment of
Chronic Uremia In and Out Patient Community
Hemodialysis Center, Trans Amer Soc Art Int
Org 10:191, 1964.
11. Esmond, W. G., Strauch, M., Baker,
B., Lewitinn, A., Attar, S., Blair, E.,
Cowley, R. Adams,- Compact Autoclavable
Counter Current Hemodialyzer with Disposable
Components. Biomedical Sciences Instrumenta-
tion, Vol. I, Plenum Press, New York, 1963.
12. Esmond, W. G., Strauch, M., Clark,
H.; Mathematical Analysis and Optimization
of a Compact, Low Cost, Pumpless, System for
Hemodialysis (Dialung). Proceedings 18th An-
nual Conference on Engineering in Medicine
and Biology 7:48, 1965.
13. Esmond, W. G., Strauch, M.; Success-
ful Treatment of a Severe Glutethimide (Dori-
den) Poisoning With An Optimized Artificial
Kidney (Dialung), Invest Uro (March or
May, 1966). In Press.
January, 1966
Chromosomal Mosaicism in Gonadal Dysgenesis
Report of a Case
HANS-DIETER TAUBERT, M.D., ERICA F. MOSZKOWSKI, M.D.*
THE ENTITY of primary amenorrhea,
short stature, webbing of the neck, and
cubitus valgus, has become known as
Turner's syndrome. It is often associated
with muhiple congenital anomalies, par-
ticularly those of the cardiovascular
system. The gamut of this syndrome may
range from the classical Turner's syn-
drome with severe defects to the so-called
pure gonadal dysgenesis,^'' where the
pathology is Hmited to the gonads. The
common pathognomonic denominator is
the absence of germ cells. The ovaries
consist merely of streaks of stromal tissue
with no ova being present. Ford^ recog-
nized in 1959 that this syndrome is
characterized by the absence of one X
chromosome, except for rare cases.^* Of
particular theoretical and practical interest
are those cases where 2 stem-lines of cells
are present. One contains the normal
modal number of chromosomes, while
the other is hypoploid due to the lack of
one X chromosome. Chromosomal
mosaicism with XO/XX configuration of
the sex chromosomes is next to XO the
most common finding in gonadal dysgene-
sis. Miller was recently able to review
over 25 reported cases. !• ^' ''• ^- !"• ^i' ^^■
"■ 1* It is the purpose of this paper to
report and discuss another case of gonadal
dysgenesis with chromosomal mosaicism.
Case Report
C. J., U. H. #29-17-32. This 15-year-old
Negro girl was first seen in the Gynecologic
Endocrine Clinic on June 30, 1964. Her chief
complaint was stunted growth, primary am-
enorrhea, and minimal development of the
secondary sex characteristics. Her height was
142.5 cm. She weighed 107 lbs.; the span was
150 cm. On general inspection the patient had
a short neck with a trace of webbing. The
chest was shield-like and the nipples wide-
spaced, small and flat. There was no areolar
pigmentation. Auxiliary and pubic hair was
sparse (Table 1, Fig. 1). Her hands were
remarkably long, with spidery fingers, and
hyperextensible joints. The palms were spoon-
shaped and could not be completely flattened.
The fourth toe on the right foot was short.
No cardiac anomalies were found. The
patient had poor vision in one eye due to
strabismus. Color vision was normal.
Examination with the patient under anes-
thesia disclosed a small cervix, atrophic labia,
and an intact hymen. There was no stimula-
tion of the vaginal mucosa. Adnexal structures
could not be palpated.
Table 1 — Malformations and Laboratory Data
A. EXTERNAL MALFORMATIONS
Webbing of the neck trace
Low implantation of the hair present
Short fourth metatarsal bone present
Epicanthic folds present
Cubitus valgus present
Arachnodactyly present
Spoon-shaped palms present
Shield-like chest with wide present
spaced nipples
Pigmented naevi absent
* From the University of Maryland School
of Medicine, Department of Obstetrics and
Gynecology.
B. RADIOLOGIC MALFORMATIONS
Sella turcica
normal
Bone age
normai
Osteoporosis
absent
C. FAMILY
Number in sibship
%
Age of mother at birth
29
Age of father at birth
33
Malformations in family
absent
Consanguinity in family
absent
X-ray, viral disease, etc. ar
ound
conception
absent
D. LABORATORY DATA
no estrogen effect
Vaginal cytology
24<7f positive
Sex-chromatin, rt. buccal c
ivity
18% positive
Sex-chromatin, It. buccal cavity
53/1000
"Drumsticks"
xo/xx
Sex-chromosome confignrat
on
44-0
Chromosome number
45-34 (51.4%)
Total urinary gonadotroph]
ns
46-32 (48.6%)
17-ketosteroid excretion
47-0
Protein-bound iodine
more than 50
Xga Proposita
mu/24 hrs.
Mother
2 mg./24 hrs.
Sister
7.7 mcg%
Dermatoglyphics
Xga ( + )
Xga ( + )
Xga ( + )
compatible
Vol. SI, Ko. 1
TAUBERT. MOSZKOWSKI— CHROMOSOMAL MOSAICISM
FiB. 1
Laboratory Data: On August 5, 1964, 26%
of the buccal mucosal cells were positive for
sex-chromatin. On March 2, 1965, a repeat
examination of both the right and left buccal
mucosa showed 24% chromatin-positive cells
on the right including 6% very small ones.
The smear on the left revealed the presence
of Barr bodies in 18% of the cells with 4%
being small ones. Fifty-three polymorpho-
nuclear leukocytes per 1,000 were found to be
posiiive for the presence of "drum sticks."
Vaginal cytology from June 30, 1964, did not
show any evidence of estrogenic stimulation.
Chromosomal Analysis: White blood cells
were cultured by a modification of the method
of Moorhead.'-' Sixty-six ceils were suitable
for analysis. Thirty-two showed the normal
modal number of 46 chromosomes. The re-
maining 34 cells lacked one of the large sub-
metacentric chromosomes of group 6-12
(Denver Classification)- or C (Patau). 15 This
was interpreted as mosaicism of the X-chromo-
somes with the following two stem-lines:
45 (XO)/46 (XX).
Gonadotrophin excretion: The 24-hour value
for total urinary' gonadotrophins exceeded 50
mouse-units (more than adult normal).
The 17-ketosteroids were 2 mg./24 hour
urine.
X-ray studies: The sella turcica was normal.
The bone age was compatible with 14.5 years.
Osteoporosis was not evident.
Dermatolglyphics:'^^ The axial triradius was
in t' position. The adt-angle exceeded 50°.
All digits with the exception of digits V sinister
showed ulnar loops. The latter had a whirl.
The total digital ridge count was 144; the
ridge count was 144; the ridge count between
triradius a and b was 58. For comparison the
same data were obtained from her younger
sister: Axial triradius t, adt-angle 45°, digital
ridge count 132 (normal range); a-b ridge
count 45 (normal); whirls on digitus I and II
right and left, and digitus III on the right.
The remaining finger had ulnar loops.
Comment
Lack of germ cells in the gonads and
loss of one X-chromosome in early de-
velopment are the notable features of this
entity. It appears that segregation and
migration of the primitive germ cells from
the hind-gut to the germinal ridge depends
upon the presence of 2 X-chromosomes.''
Embryonal cells do not show many
chromocenters prior to day 16-18 of de-
velopment. After segregation of the primi-
tive germ cells, however, one of them be-
comes genetically inactive and as such
January, 1966
13
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
the chromocenter or the Barr body.* Fail-
ure of the primitive germ cells to arrive at
the germinal ridge seems to arrest the
gonad at the stage of the primitive, in-
different medulla.'' Any other cause
which will prevent this migration will have
the same result in gonadal development.
This explains chromatin-positive cases of
gonadal dysgenesis with normal 46/XX
karyotype.
In a case as ours one has to assume that
the germ cells descended from a stem-line
with the karyotype 45/XO. Examination
of more than one tissue could possibly
have uncovered an even more complex
system of multiple mosaicism. Differences
in the percentages of chromatin-positive
cells from either buccal mucosa have been
observed.*
The observed difference of 18% and
24% respectively cannot be considered
significant in this context.
Pre-zygotic maternal or paternal non-
disjunction during the first or second
meiotic division is thought to be the cause
for aneuploid states such as gonadal dys-
genesis, Klinefelter's syndrome, autosomal
trisomies, et cetera. In contrast, chro-
mosomal mosaics are beheved to origi-
nate from faulty division of the zy-
gote.^ * ^ Mitiotic non-disjunction or loss
of an X-chromosome due to anaphase lag
have been postulated as possible mecha-
nisms.
The maternal or paternal origin of the
X-chromosome in such individual can be
studied by investigating sex linked traits.
Color blindness, glucose-6-phosphate-
dehydrogenase deficiency, and Duchenne's
atrophy were not applicable in the case
presented. Determination of the Xg blood
group can be most helpful in this aspect,
since presence of the Xg'' (-f) allele
assures dominance of the trait. ^-^ Since
all accessible members of the family were
Xg^ ( + ). no further information could
be gained in this aspect.
Mitotic non-disjunction at the first i
cleavage division would have resulted in
an X/XXX embryo. The triple-X stem-
line would be recognizable by virtue of
the supernumerary chromosome. A num-
ber of buccal smear cells would contain
2 Barr bodies, representing 2 inacti-
vated X-chromosomes. The most likely
explanation is that an XX zygote lost
one of the sex chromosomes during ana-
phase at the first cleavage division, re-
sulting in equal proportions of XO/XX
cells as observed. This cell type could
also have originated in mitotic non-dis-
junction at the second cleavage division.
However, one would have to assume that
the zygote was originally XO, and the
proportion between the 2 cell lines should
not be even.
Dermatoglyphic examinations have
been used successfully in characterizing
various congenital anomalies. The con-
figuration of the dermal ridges are laid
down at a very early stage of develop-
ment, around the third month. i* The
propositus showed some of the typical
findings: t' position of the axial triradius,
increased adt-angle, and an increased
dermal ridge count.
Treatment
The patient was placed on estrogen-
substitution therapy with the aim to in-
duce development of the secondary sex
characteristics, and hopefully to induce
further growth. Figure 2 attests to
the effectiveness of this regimen as to the
former, e.g., after 6 months of 0.2 mg. of
stilbestrol, q.d. No further growth oc-
curred. Cyclic therapy will be instituted
for induction of menstrual cycles as soon
as the development of the genitalia is
sufficient.
Summary
A 15-year-old-Negro girl presented
with stunted growth, primary amenorrhea,
and lacking development of the secondary
14
Vol. 51, No. 1
TAUBERT, MOSZKOWSKI— CHROMOSOMAL MOSAICISM
sex characteristics. Chromosomal analy-
sis confirmed the clinical impression of
gonadal dysgenesis. The karyotype pre-
sented as a mosaic containing two cell
lines: 45 (XO)/46 (XX). Estrogenic
replacement therapy resulted in satis-
factory development of the secondary sex
characteristics. The origin of the chromo-
somal defect was discussed.
Acknowledgment
The help of Miss E. Jahn of the Baltimore
Rh-Typing Laboratory in obtaining the Xg-
Typing is gratefully acknowledged.
References
1. De La Chapelle, A: Cytogenetical and
Clinical Observations in Female Gonadal Dys-
genesis, Ada Endocr., 65.1, 1962 (Suppl.).
2. Editorial: A Proposed Standard Nomen-
clature of Human Mitotic Chromosomes, Amer.
J. Human Genet., i2;384.
3. Ford, C. E., Jones, K. W., Polani, P. E.,
De Almeida, J. C, and Briggs, J. H.: A Sex
Chromosome Anomaly in a Case of Gonadal
Dysgenesis, Lancet, i.-711, 1959.
4. Froland, A., JOHNSEN, S. G., Andersen,
P., Dein, E., Sanger, and Race, R. R.: Non-
disjunction and XXY Men, Lancet, 2.1121-22,
1963.
5. Griboff, S. O. and Lawrence, R: The
Chromosomal Etiology of Congenital Gonadal
Defects, Amer. J. Med., i0.-544-563, 1961.
6. Grumbach, M. M. and Morishima, A.:
Sex Chromatin and the Sex Chromosomes:
On the Origin of Sex Chromatin from a Single
X Chromosome, Acta CytoL, <5;46-60, Jan. -Feb.
1962.
7. Jones, H. W., Ferguson-Smith, M. A.,
and Heller, R. H.: The Pathology and Cyto-
genetics of Gonadal Agenesis, Amer. J. Obstet.
Gynec, 87:51?,, 1963.
8. LiNDSTEN, J.: The Nature and Origin of
X Chromosome Aberrations in Turner's Syn-
drome, Almquist and Wiksell, Stockholm, 1963.
9. LiNDSTEN, J., et al.: Source of the X
in XO Females: The Evidence of X7, Lancet,
/.■558-559, 1963.
10. Mellinger, M.: Turner's Syndrome
with XO/XX Mosaicism, Henry Ford Hasp.
Med. Bull., i2.-181-186, 1964.
11. MiKKELSEN, M., Froland, A., and
Ellebjerg, J.: XO/XX Mosaicism in a Pair
of Presumably Monozygotic Twins with Dif-
ferent Phenotypes, Cytogenetics, 2.-86-98, 1963.
12. Miller, O. J.: The Sex Chromosome
Anomalies, Amer. J. Obstet. Gynec, 90.1078,
1964.
January, 1966
15
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
13. MOORHEAD, P. S., NOWELL, P. C, MELL-
MAN, N. J., Battipps, D. M., and Hunger-
ford, D. A.: Chromosome Preparations of
Leukocytes Cultured from Human Peripheral
Blood, Exp. Cell. Res., 20:613, 1960.
14. MoszKOwsKi, E. F., De Luca, L., and
Taubert, H. D.: Pure Gonadal Dysgenesis,
Obslet. & Gynec, 25:329, 1965.
15. Patau, K. : Chromosome Identification
and the Denver Report, Lancet, 1:933, 1961.
16. Penrose, L. S.: Fingerprints, Palms and
Chromosomes, Nature. 197:933, 1963.
17. Vaharu, T., Voorhess, M. L., Leibow,
L. G., Cara, J., Patton, R. G., and Gardner,
L. I,: XX/XO Mosaicism in a Girl, /. Pediat.,
6/.750-754, 1962.
18. Van Wijk, J. A. M., Blankenborg,
G. J., and Stolte, L. A. M.: XO/XX Mosaic-
ism and Mongolism in the Same Person, Lancet,
/.■171, 1964.
19. Warren, J. C, Erkman, B., Cheatum,
S., and HOLMAN, G.: Hilus Cell Adenoma in a
Dysgenetic Gonad with XX/XO Mosaicism,
Lancet, i.141-143, 1963.
Vol. 51, No. 1
MEDICAL SCHOOL SECTION
Dear Students, Members of the Alumni, and Friends of the Medical
School:
The accumulation of knowledge has greatly increased the necessity
that medical science be taught and understood in an integrated
manner. The function of cells, organs and systems are so inter-
related that the various disciplines dealing with them must be taught
in a coordinated manner. This is effected by having the Curriculum
and Instruction Committee made up of faculty members that repre-
sent the medical faculty as a whole rather than their department.
These individuals are usually younger faculty with less established
standing in the departmental structure. This makes it easier for
them to accept and appreciate the necessity to present overall infor-
mation in a coordinated way. For example, the kidney and kidney
function is taught on a structural, functional basis and the influence
of abnormal factors, including disease, is presented at the same time.
This involves an integrated presentation from the viewpoints of
anatomy, physiology, endocrinology, neurology, pathology and finally
clinical pharmacology.
The difference between older methods of teaching and those now
in vogue is primarily the teaching of all of these subjects in an
integrated way rather than isolated departmental presentations with
considerable separation due to time.
The Faculty Curriculum and Instruction Committee of this Medical
School is effectively working to bring about these changes in the
medical education program at Maryland.
Sincerely,
William S. Stone, M.D.
Dean
January, 1966
Reorganization of School Administration
With the retirement of Dr. D. C.
Smith, some reorganization has taken place
in the Administration of Curriculum,
Student Affairs, and Admissions in the
School of Medicine. Dean Stone has nomi-
nated three assistant deans.
Three members of the faculty have been
invited to serve as assistant deans. The
first of these is Dr. Eugene J. Linberg,
assistant professor of surgery who will serve
as assistant dean for Curriculum and In-
struction.
Dr. Linberg's areas of responsibility will
include studies of the curriculum of the
School of Medicine and methods of in-
struction. He will also give attention to
the coordination of special lectures and will
be responsible for class scheduling and
student section assignments.
Other studies will include the coordination
of student research projects, counseling and
planning of the use of free time by students
and the important duty of scheduling
National and State Board examinations for
the second and fourth year classes. He
will serve as chairman of the Honors Com-
mittee and will conduct a follow-up of gradu-
ates performance and career development.
He will be responsible for the care of
student records and grades.
Dr. Karl H. Weaver of the department
of pediatrics will serve as assistant dean
for admissions. Dr. Weaver's areas of re-
sponsibility will include the important post
of chairman of the Admissions Committee.
He will also edit and prepare the catalog
of the School of Medicine. He will act
as liasion on admissions for the Association
of American Medical Colleges and will con-
duct studies of admissions data including
student selection. He will conduct a follow-
up on student performance from the ad-
missions viewpoint. He will be concerned
with admission problems of graduate
DR. WEAVER
DR. ROSENHOLTZ
Vol. 51, No. 1
MEDICAL SCHOOL SECTION
students as they are involved in the School
of Medicine. Dr. Weaver will also serve
as coordinator with premedical advisers
in the numerous colleges and universities
from which applications are received.
Dr. Mitchell J. Rosenholtz, assistant pro-
fessor of pathology, will serve as assistant
dean for Student Affairs. This important
area of responsibility will include the re-
sponsibility as secretary for the Faculty
Committee on Scholarships and Loans. Dr.
Rosenholtz will also serve as liaison with
students and student advisors and will con-
duct the" Freshman and Junior Orientation
programs in September of each year. He
w ill serve as chairman of the Student Activi-
ties Committee and chairman of the Student
Advancement Committee counseling on con-
ditions and failures. He will advise the
Dean on matters of student discipline.
Dr. Rosenholtz will also study the matters
of student social liaison, student informa-
tion and will maintain student registration
and Blue Cross records. He will serve as
liaison on the national intern matching pro-
gram. He will also be responsible for the
student aspects of the precommencement
and commencement exercises.
Dr. Stone advises the Bulletin that
while there are many overlapping areas
of responsibility, the three assistant deans
will work in close cooperation with Dr.
Stone in order to provide a smooth work-
ing and efficient administrative team.
January, 1966
Dr. Bradley Retires as Pediatric Head
Dr. J. Edmund Bradley, for many years
professor and chairman of the department
of pediatrics at the School of Medicine, re-
tired on September 1, 1965, after 31 years
of service to the School of Medicine, 17
of them as head of the Department of
Pediatrics.
A physician of the old tradition. Dr.
Bradley was in part-time private practice
for a number of years before being named
full-time professor of pediatrics. Despite an
intense scientific program, Dr. Bradley
always maintained a child-oriented depart-
ment, championed by his personal kindliness
and consideration.
During his tenure, a number of precedents
and developments occurred. He established
a unique pediatric research laboratory to
explore fundamental problems encountered
in clinical pediatrics. He introduced many
innovations in patient care, not alone with
the hospital but in the out-patient clinics
conducted throughout the state as well as
in the City of Baltimore. He organized a
teaching program for medical students and
a training program for interns and residents
rated in 1964 as "one of the top 5 programs
in the nation." He maintained as well an
active connection with the Department of
Psychiatry. The Department of Pediatrics
was actively affiliated with the Lutheran
Hospital of Maryland.
Dr. Bradley always felt a deep obligation
to the community that prompted him during
his tenure at the University to initiate and
to participate in innumerable projects that
have vastly increased the contribution of
the university to the welfare of children
and their parents throughout the Sate of
Maryland.
A few of Dr. Bradley's accomplishments
may serve to indicate the wide range of
his influence. In the field of science, he
was the first to observe and describe hyper-
tension in children associated with Wilm's
tumor. He also developed a number of
successful and widely used treatments for
controlling epidemic viral vomiting. He
brought attention to the high incidence of
lead poisoning among the lower socioeco-
nomic groups in the City of Baltimore and
his work in the pediatric research laboratory
led to effective treatment for lead encephalo-
pathy. Due to his recognition of the cause
Vol. 51, No. 1
MEDICAL SCHOOL SECTION
of lead poisoning the incidence of serious
lead intoxication was reduced through early
recognition and prompt treatment in clinics,
including the one he established at the Uni-
versity Hospital.
He was among the first to correlate poly-
cythemia and pheochromocytoma and to
identify its cause as erythropoietin, a sub-
stance secreted by the adrenal.
Dr. Bradley was consultant to several
publications, including Current Medical
Digest, and was himself the author of more
than 50 scientific publications.
During his tenure, a high degree of ex-
cellence in both undergraduate and post-
graduate pediatric teaching was maintained.
He extended the medical school's training
program in pediatrics to a number of com-
munity hospitals in Baltimore, including the
Lutheran Hospital, in order to improve the
care of children in those institutions. He
developed the first pediatric outpatient clinic
at the Provident Hospital. The first two
Negro physicians to complete a program
of training in pediatrics were later certified
by the American Board and entered active
practice in this specialty.
Working with Dr. Allen F. Voshell,
director of Kernan's Hospital, Dr. Bradley
consummated an agreement to provide pedi-
atric resident coverage there as well as at
the St. Agnes and Bon Secours Hospitals.
A consultant's consultant. Dr. Bradley was
always available for general advice to the
City Health Department and state officials.
He served on numerous councils, boards,
and committees including the State Council
of Medical Care (1952-1961), the State
Board of Health and Mental Hygiene (1961,
reappointed to 1971), the Steering Com-
mittee on Mental Retardation (1964), the
Organizational Committee of the State
Board of Health and Mental Hygiene
( 1961 ), the Staffing Committee of the Board
of Health aad Mental Hygiene (since 1961 ),
and the Committee of the Fetus and the
Newborn of the American Academy of
Pediatrics (1958-1964).
As a member of the Committee on State
Planning for the Handicapped Children, he
helped establish the Central Evaluation and
Diagnostic Clinics at the University of
Maryland and the Johns Hopkins Uni-
versity.
He was a member of the Committee on
Planning for Residential Centers for the
Mentally Retarded, and worked with the
Sisters of St. Francis in establishing a school
for the mentally retarded, and with the
Sisters of St. Gabriel's to establish a home
for similarly afflicted children.
He was instrumental in instituting and
organizing pediatric psychiatry in the
Psychiatric Institute of the University of
Maryland and later in the establishment of
an in-patient unit for children there. He
also laid the ground work for the develop-
ment of a cooperative research program
between the School of Medicine and the
Rosewood State Hospital for mentally re-
tarded children.
Dr. Bradley was President of the Uni-
versity Hospital's medical staff in 1952 and
in 1954. He was chairman of the executive
committee of St. Joseph's Hospital for two
years and later secretary of the pediatric
section of the Baltimore City Medical So-
ciety. He was secretary and treasurer of
Alpha Omega Alpha Honorary Society in
Maryland from 1953 to 1956 and later
served as counselor of the chapter from
1956 to 1959. He was a member of the
Board of Trustees of the Hospital Council of
Maryland and member of the University
of Maryland Senate.
Dr. Bradley, a native Baltimorean, is an
alumnus of Loyola College and of the
Georgetown University School of Medicine.
Upon his retirement members of his depart-
ment presented the School of Medicine with
an excellent portrait by Stanislav Rembski
which is reproduced herein.
Dr. Bradley, upon retirement, moved to
his favorite second home on Cape Cod,
Massachusetts. However, after a short rest,
he plans to be available for such consultation
and advice as could be of use in the ad-
vancement of pediatrics, his chosen specialty,
and the field in which this great humani-
tarian, physician, scholar, and administrator
has created for himself an enviable place
and a distinguished reputation.
January, 1966
faculty
NOTES
Dr. Samuel P. Bessman, professor of
pediatric research, spoke on the subject of
fluid balance at the Children's Hospital in
Akron, Ohio, on October 26th, and the fol-
lowing day at the Mayo Clinic in Rochester,
Minnesota.
Dr. Samuel P. Bessman, professor of
pediatric research, was one of 3 co-chairmen
at the scientific seminars held at the Rose-
wood State Hospital on November 21, 1965.
Dr. John M. Dennis, professor and
chairman of the department of radiology
and for several years president of the
Maryland Division, American Cancer So-
ciety, was honored by the society on the
occasion of a recent meeting of the board
of directors. Dr. Dennis was presented with
the American Cancer Society's bronze medal
and certificate in recognition of his out-
standing contributions to the control of
cancer. Dr. Dennis will continue as a mem-
ber of the board of directors of the Mary-
land division.
On the occasion of the Thirteenth Post-
graduate Course, the 1966 Diabetes in Re-
view, sponsored by the American Diabetes
Association at the Mayflower Hotel in Wash-
ington, D. C, a paper entitled "The Action
of Insulin" was presented by Dr. Samuel
P. Bessman, professor of pediatric research
and professor of biochemistry at the School
of Medicine.
Dr. Emil Blair, assistant professor of
surgery, is on sabbatical leave for a year
at Sweden's oldest medical school, the Uni-
versity of Uppsala, where he will participate
in all activities of the department of thor-
acic surgery.
ANATOMISTS VISIT BALTIMORE
Many years ago anatomists were pri-
marily descriptive morphologists. Now,
many study living tissues — in four di-
mensions (3 of space, and one of time) —
and anatomy and physiology become one.
Anatomists dissect tissues and cells with
the electron microscope, magnify intracellu-
lar particles many thousands of times until
they are, in fact, studying the anatomy of
protein molecules, i.e., biochemical anatomy.
It has been well said that anatomy today
is anything that an anatomist thinks about.
On November 19 and 20, more than 100
members of the Southern Society of Anato-
mists, representing over 40 American
medical schools and 5 foreign universities,
met at the University of Maryland School
of Medicine. More than 30 papers were
presented at sessions held in Davidge Hall.
They ranged in subject matter from gross
anatomy, histochemistry, neuroanatomy
endocrinology, muscle physiology, hypo-
thermia, comparative anatomy, pulmonary
anatomy, and physiology to electron micro-
scopy.
Dr. Vernon E. Krahl, professor in the
department of anatomy, as this year's presi-
dent of the Southern Society of Anatomists,
was host to the membership in Baltimore.
Following the formal program on Friday,
November 19, the group enjoyed a social
hour followed by the annual dinner in La
Ronde, atop the Holiday Inn, seeing a re-
volving, panoramic view of Baltimore by
night. Featured speakers at the dinner pro-
gram were Dr. Albin O. Kuhn, vice presi-
dent for the Baltimore Campuses of the
University of Maryland, and Dr. John Z.
Bowers, director of the Josiah Macy
Foundation.
In addition to papers from the platform
and annual business meeting, Saturday's pro-
gram included a symposium on "Novel
Methods of Teaching Anatomy," in which
members of the society demonstrated special
and original techniques for helping medical
and dental students to understand and re-
member key facts and relationships in their
studies of human anatomy.
The Southern Society of Anatomists
Vol SI, No. 1
MEDICAL SCHOOL SECTION
serves several useful and important roles in
anatomical teaching and research today. It
not only provides, in the Fall, an oppor-
tunity for the exchange of information and
ideas as well as the regular Spring meeting
of the national group (The American As-
sociation of Anatomists) but it has been
able to maintain a single-session format and
a less formal atmosphere in which medical
and graduate students, too, may have a
podium and a less formidable, perhaps more
sympathetic, audience than at the larger,
multiple-session meetings of the national
organization. Formerly, each medical school
was required to devise its own summer
teaching program in anatomy for its weaker
students, repeaters, etc. Now, under the
aegis of the Southern Society of Anatomists,
it has been arranged so that in any par-
ticular summer only one of some 25
southern medical schools is obliged to
offer a comprehensive course in anatomy.
Students of the member schools, needing
to strengthen their grasp of anatomy, attend
these special courses. Thus, just one, not
25, schools is obliged to engage its faculty
of anatomy in summer teaching.
During the recent meetings, architectural
features of Davidge Hall, such as hidden
dissecting rooms and secret spiral stair-
cases (reminiscent of the early days when
an aroused populace often objected to
human dissection), were opened and dis-
played to the visitors. This reminded an-
atomists of their stormy early history and
of the fact that the University of Maryland
was the first American medical school to
require human dissection as part of the
regular medical curriculum. They were
also reminded that Davidge Hall is the
oldest building in America to be used con-
tinuously in medical education since its
erection in 1812. — Vernon E. Krahl, M.D.
January, 1966
Los Auiigos de Cajal Dedicate Memorial Bust at Petilla
At dedication ceremonies attended by
more than 30 American and Spanish neu-
rologists, a bust of Santiago Roman y Cajal
was dedicated at Petilla on Tuesday, Sep-
tember 14, 1965.
The Amigos organization, an international
group, was headed by Dr. Charles Van Bus-
kirk of York, Pennsylvania and a member
of the faculty of the School of Medicine.
The European organization was headed by
Dr. Alberto Portera, formerly of the staff
of the School of Medicine of the University
of Maryland, and now practicing neurologist
in Madrid.
Early in 1965, prominent American and
Canadian neurologists were contacted con-
cerning the development of a memorial to
be placed at the birthplace of the eminent
neurohistologist. More than 115 sub-
scriptions were received following which
the preparation of the bronze head of Cajal
proceeded.
Following the conclusion of the Inter-
national Neurologic Congress in Vienna, the
group gathered in Madrid and under the
guidance of Dr. and Mrs. Portera con-
cluded a tour of the environment of Cajal
and viewed the numerous monuments and
memorials to him including a visit to the
Cajal Institute where the group viewed
Bust of Don Santiago Ri
an y Cajal in its present
de of the village church
Petilla.
Don Luis Ramon y Cajal speaks at nnveilinff ceremony.
viii
the original work bench and equipment with
which the important discoveries were made
and, as well, the memorabilia of the honors
and awards which came to Cajal in his
later years. This was followed by a bus
journey to Zaragoza and a visit to the
school of medicine where Cajal studied as
a young man and where he later began
his anatomic work. This was followed by a
journey to Haja and then to Petilla where
the ceremonies were held.
From the local press the following is ex-
tracted:
Yesterday in the Navarrese town of Pe-
tilla de Aragon, American and Spanish repre-
sentatives of the friends of Cajal rendered
homage to the illustrious scientist, born in
Fo/. 51, No. 1
View on Main Street of Petilla.
that town. This homage consisted of the
placing of a bust donated by the friends of
Cajal, dedicated in a simple act participated
in by provincial and local authorities and
the entire population of the town of Petilla,
a small town in Aragon perched on a
sheltered crag under the protection of the
bold rocks so common in that portion of
Spain.
The simple and solmen act was performed
in the town square adjacent to the parish
church. Outside, in the porticoes awaited
the local authordities including the president
of Navarre, Don Felix Hurate, the deputy
for the district, Don Amadeo Marco, the
provincial health officer, Don Javier Vinas,
the district deputy of Sos, Don Feli.x Cuellar,
the president of the Physicians College of
Pamplona, Dr. Garro, the secretary of the
Prince of Viana Institution, Senor Uranga,
the president of the Royal Academy of
Zaragoza, Dr. Oliver Rubio, the mayor of
Petilla, Senor Sanchez Gaston.
The group then proceded to the portico
of the small church where Dr. Van Buskirk
of York, Pennsylvania and his group were
met by the officials and the parish priest,
Don Jesus Auricinea. From the parish
archives was then read the certificate of
birth and baptism of Cajal, a simultaneous
translation into English being provided by
Dr. Portera.
"At 9 P.M., May 1, 1925, was born
and the following day was solemnly bap-
tised by me, the undersigned vicar, a boy
child who was named Santiago Felipe,
legitimate son of Fausto Ramon, surgeon
and Antonia Cajal, native of Larres and
resident in this town. Paternal grand-
parents, Esteban Ramon, farmer, native
of Isin, Province of Huesca, and Rosa
Casasus, native of Larres, Province of
Huesca. Maternal grandparents, Lorenzo
Cajal, weaver, native of Asso, Province
of Huesca, and Isabel Fuente, native of
Larres, Province of Huesca. The god-
parents were Francisco Sanchez, native
of Petilla, province of Navarre, and Anna
Maria Iriarte, native of Isuerre, Province
of Zaragoza, whom I admonished of the
spiritual parenthood and the obligations
which they were contracting. Registered,
signed, Toribio Barnechea, vicar of Pe-
tilla."
At this time a film entitled "The Environ-
ment of Santiago Cajal" prepared in Spanish
by Drs. Van Buskirk and Portera was
shown for the first time to the audience con-
sisting mainly of residents of Petilla and the
official party. This was followed by the
simple act of unveiling the bust. Cajal's son,
Don Luis Ramon y Cajal, was present at
the ceremony and uttered some brief moving
words to express his gratitude. He was fol-
lowed by Dr. Carrato, director of the Ramon
y Cajal Institute of Madrid, who in English
thanked the "Friends of Cajal" for their
initiative. Dr. Castro, professor of histology
of the Faculty of Medicine of Madrid, a
favorite student of the great man, summed
up with simple clarity the contribution which
Cajal made to the world of science, con-
densed, including the neuronal theory, much
discussed 50 years ago and which today
is accepted by all neurologists. Dr. Castro
concluded with reference to the many
thousands of discoveries which are attributed
to Cajal and which serve today as guide-
lines of present day investigation. His ad-
dress was followed by remarks by Senor
Huarte who reviewed the life of Cajal and
finally amidst the applause of all the by-
standers. Dr. Van Buskirk and the mayor
of Petilla, Senor Sanchez Gaston, unveiled
the bust, terminating the ceremony. The
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
official party was next entertained at
lunclieon, departing for Zaragoza that eve-
ning.
A full account of the proceedings was
contained in the Heraldo de Aragon of the
day.
Those participating in the ceremonies at
Petilla included: Dr. Carrato Ibanez, Dr.
Castro, Dr. Aguirre, Dr. Calderon, (Mr.)
Louis Ramon y Cajal, Srta. M. de los
Angeles Gasset, Dr. Estevez, Col. Hoffman
U.S.A.F., Dr. Smith, Dr. Charles Van Bus-
kirk, Dr. Francis W. Ramsay, Dr. A. M.
Rabiner, Dr Juan Bravo of Madrid.
Contributors to the Cajal Memorial
Fund included the following physicians:
Allen, J. N., Alpers, B. J., Anderson, W. W.,
Arnold, J. G., Bailey, A. A., Blue, W. W.,
Boldrey, E. B., Bordley, J., Coblentz, R. S.,
Cotter, E., Courtois, G. A., Crosby, E. C,
Currier, R., Davidson, L., DeJong, R.,
Drachman, D. B., Echlin, F. A., Elkes, J.,
Reindel, W., Fox, C, Gantt, H., Garvin,
J. S., Gibson, W. C, Groff, R. A., Gurdsgian,
E. S., Hearn, J. B., Heath, R. G., Heck, A.,
Henderson, C. M., Hills, J. R., Hinsey, J. C,
Horenstein, S., Hulfish, B., Humphrey, T.,
Ingram, W. R., Jacobs, H., Jousse, A. T.,
Joynt, R. J. Kane, C. A., Koenig, H.,
Konigsmark, B. W., Kurland, L. T., Kurtzke,
J., Lemni, H., Madow, K., Magee, R. R.,
Matzke, H. A., Mericle, E. W., Mettler,
F. A., Miller, Z. R., Millikan, C. H., Moore,
M. T., Mosberg, W., McNaughton, F. L.,
Nauta, W., Nelson. E., Odom, G. L., Olden-
dorf, W. H., Parkinson, D., Peele, T. L.,
Penfield, W., Porter, H., Quadfasel, F. A.,
Rabiner, A. M., Ramsey, F. W., Rasmussen,
T., Richardson, E. P., Richter, R. B., Robb,
J. R., Roizin, L., Rose, J. E., Rosenbaum,
H., Ross, A. T., Scharenberg, K., Schlez-
inger, N. S., Schmidt, R., Schuster, F. F.,
Scoville, W. B., Segarra, J. M., Shapiro, S.,
Smith, B., Smith, B. H., Snider, R. S.,
Soc. Clin. Neurol., Speakman, T. J., Steeg-
man, A. T., Stein, J. M., Sullivan, J. F.,
Sweet, W. H., Tarlov, M., Taylor, R. A.,
Teasdall, R., Thompson, H. G., Toman,
J. E. P., Torres, F., Toupin, H. M., Truex,
R. C, Tucker, J. C, Utterback, R., Van
Buskirk, C, Von Benin, G., Wagner, J.,
Walker, A. E., Walsh, F. B., Watson, C. W.,
Weiz, S., Whelan, J., Windle, W. F., Wol-
barsht, M., Woodson, F. G., Yakovlev, P.
of Cajal (L to R) : Dr. Portera. Madrid:
ravo. Madrid: and Dr. Wagner, U. S. A.
Vol 51. No. 1
ALUMNI ASSOCIATION SECTION
President's Letter
MEDICAL
ALVMM ASSOCIATION
Officers 1965-66
C. Parke Scarborough. M.D.
President
Howard B, XrAvs. M.D.
Prcsidcniclect
Lewis Klair Woodward. M.D.
I 'iccPrcsidcnt
John A. Mora.v, M D.
ricc-Prcsidcot
Morris Nicholson. M.D.
Vke-Prcsidoit
Walter E. Karfcin. M.D.
William H. Triplett. M.D.
E.rfcuth'c Director
^^RS. Louise Girkin-
F.xceutive Secretary
Board of Directors
William J. Supik. ^LD.
Hugh B. McXally, M.D.
Emmanuel A. Schimunek, M.D.
William H. Kammer, Jr.. M.D.
Robert B. Goldsteix, M.D.
John D. Young. Jr.. M.D.
Harry C. Bowie, M.D.
John O. Sharrett, M.D.
Theodore E. Stacy, M.D.
Secretary
Gibson J. Wells, M.D.
cx-officio
J. Howard Franz, M.D.
Nominatins: Co
Gibson J. Weli
Chairman
mittee
M.D.
, M.D.
J. Howard Fran
er-officio
Emmanuel Schimunek, M.D.
Wilford Townshend, Jr., M.D.
Donald H. Dembo. M.D.
Repr
ntati'
to
neral Alu
Parke S
E. I. Cornbrooks, M.D.
William H. Triplett, M.D.
Representatives to
Editorial Board, BULLETIN
John C. Krantz, Jr., Ph.D.
John F. Savage, ^LD.
Arthur G. Siwinski, M.D.
C. Parke Scarborough, M.D.
Representatives to
Faculty Board (3 year term)
C. Parke Scarborough, M.D.
Howard B. Mays, M.D.
Fellow Medical Aluiniii:
Five years ago the surgical faculty of the medical
school decided to form a surgical society composed of
the faculty, former surgical residents of the University
Hospital, and faculty members and former surgical resi-
dents of affiliated hospitals and thus came into being
the University of Maryland Surgical Society. The fol-
lowing year members of the department of internal
medicine started a similar group. Many years previously
the obstetrical and gynecological department had organ-
ized the Douglass Society and subsequently the pedia-
tricians joined together in a like manner. Each of these
societies started a program and periodic meetings which
grew in interest and attendance.
Two years ago a new precedent was set when all
four of these organizations joined together with the
University of Maryland Medical Alumni Association
in a joint professional and social reunion. This was a
tremendous success and it was unanimously agreed that
this reunion should be repeated in two years, to be
renewed at the end of each two year span. 1966
marks the first renewal of this program.
Dr. John Sharrett, the general chairman of the affair,
has been working diligently since May 1965 on the
1966 meeting. The chairmen of the other groups have
met with Dr. Sharrett and have outlined most im-
pressive individual society programs. Abstracts of
papers presented for approval have arrived from many
states and numerous foreign countries. Tentative ar-
rangements have been made for a special issue of the
American Surgeon to be turned over to this year's
surgical program and similar arrangements have been
made by the groups in medicine, obstetrics and gyne-
cology, and pediatrics. This reunion is increasing in
interest and of importance to us all and we may well
be proud of this which the University of Maryland has
created. This may well set a pattern for other organiza-
tions and may be copied by other medical institutions.
Continued on page xv
January. 1966 xi
The University of Mar>
Statement of Cash Receipts and E
Cash Balances, May 1, 1964:
Maryland National Bank — Bulletin Fund SI , 788 . 44
—Alumni P^und 4,433.38 S 6,221.82
—Savings Account 5,000.00
Eutaw Savings Bank — Funded Reserve 15,902.75
Baltimore Federal Savings & Loan Association —
Student Loan Fund 1 ,007.51
Cash on hand 'lOO.OO 828,232.08
Receipts:
Bulletin Fund — Contributions S 3,216.00
Alumni Fund:
Dues $7,518.00
Annual Banquet 2 , 072 . 00
Ladies' Activities 114. 75
Savings Account Interest 176.40
Oyster Roast 385 . 00
Miscellaneous 8. 75
Contribution from OB & Gyn Societies.. 583.23
Board Meeting Dinner Reimbursements. 57.75 10.915.88
Funded Reserve — Interest 622 13
Student Loan Fund :
Contributions $ 505.00
Interest 42.76 547.76 15,301.77
TOTAL CASH TO ACCOUNT FOR §43 533 85
Expenditures:
Bulletin Fund:
Fee— Editor $1 ,000.00
Bulletin Account —
University of Maryland 3,500.00 8 4,500.00
Alumni Fund :
Salaries $3,970.15
Fee— Exec. Secy 500 . 00
Payroll Taxes 152 . 96
Printing and Office Supplies 267 . 41
Postage 383.91
Alumni Day (1964) Expense 5,761.77
Alumni Day (1965) Expense 85.16
Board Meeting Luncheon 106. 75
Auditing 150.00
Miscellaneous 202.88
Oyster Roast 570.00
Contribution to Bulletin 2,000.00 14,150.99
Vol. 51, No. 1
cal Aliiinni Association
or the v^ar ended April 30, 1965
Cash Balances. April 30, 1965:
Marvlaml National Bank — Bulletin Fund S 504.44
— Ai.uMNi Kund 1,114.87 S 1,619.31
— Savintjs Account 5,176.40
Eutaw Savings Bank — Funded Reserve 16,524.88
Baltimore Federal Savins:s & Loan Association —
Student Loan Fund . . T 1,555.27
Cash on Hand 7.00 S24,882.86
TOT.\L CASH ACCOUNTED FOR $43 , 533 . 85
Student loans of $4,900.30 were outstanding at April 30, 1965.
Abstract of Minutes of Board of Directors
A meeting of the Board of Directors was
held on Oct. 12, 1965. Minutes of the
previous meeting were approved. The
Treasurer's Report was given and the bal-
ance on hand showed the association to be
in good condition. Treasurer's Report was
accepted.
At the previous meeting the president was
asked to appoint a committee to study what
involvement the Alumni Association should
undertake in respect to functions held at
out-of-town meetings. Dr. Scarborough,
president, reported that Dr. Supik had ac-
cepted appointment as chairman of this
committee.
The committee to distribute pamphlets
known as "Research and Educational Ac-
tivities, Department of Medicine, Univ. of
Md.," whose chairman is Dr. Lisansky, has
recommended that a copy of the pamphlet
be sent to each member of the senior class.
It was reported they have been sent by the
Alumni Office.
A note from Miss Beth Wilson calls our
attention to the documentaries WBAL-TV
is preparing. One will be titled, "The
Anatomy of Medical Education" and wiU
follow a medical student through his four
years at the Univ. of Md. The other will
be a historical documentary about the
Medical School, centered around Davidge
Hall and the events it has witnessed. It will
feature such persons as Dr. Nathan Smith,
Dr. John Crawford, Dr. Francis Donald-
son, Dr. Robley Dunglison and other
physicians who are responsible for the tra-
ditions of our Medical School. These are
long-term projects and we are told each
one may be many months in the making.
Dr. Sharrett, chairman of the 1966 Mary-
land Medical Reunion which will coordi-
nate their activities with Alumni Day to
be held May 5, 6, and 7, 1966, reported
that he has talked with Dr. Arlie Mans-
berger who will be responsible for plan-
ning the program of the Surgical Society,
and Dr. Edmund B. Middleton, who will
be responsible for the plans of the Ob-
stetrical and Gynecological Society. He
has yet to learn who will be responsible for
making plans for the programs of the
Hospital Medical Society.
Gifts from Dr. Theodore McCann Davis,
class of 1914, totaling $510.00 were re-
ported to have been received and deposited.
A memo from Arnold Blaustein, class of
1966, brought forth information that Alpha
Omega Alpha together with the Student
Januarv, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Council now sponsors a Medical History
Society. They plan to hold 3 or 4 meetings
a year and wondered whether our board
might have a good suggestion for a speaker.
It was felt that here is something that
corresponds with interests of the board.
Possible speakers for them were suggested.
At the November 10th meeting of the
board Dr. Scarborough, president, reported
the Honor Award Committee, composed of
Drs. Morris, Clemson and Young, has met
and sent to him their nominee for the re-
cipient of the Annual Honor Award and
Gold Key. Unanimous approval of the
board to their choice of Dr. T. Nelson
Carey as recipient of his honor was given
heartily. Dr. Scarborough will see that Dr.
Carey is notified officially.
Dr. Scarborough announced that he has
contacted Dr. Krantz and requested that he
accept appointment to the editorial board
of the Bulletin, to represent the Medical
Alumni Association. Dr. Krantz has ac-
cepted the appointment.
The December meeting of the board will
be dispensed with and the next meeting will
be held in January.
Respectfully submitted,
Theodore Kardash,
Secretary
BaUartVs Genealogy of School
of Jiedicine a Success
newly published A UNtVERSMTY MS BORN
well received by public
An important historical volume, a genealogy of the School of Medicine,
relating to the early days of the University of Maryland and its development,
has been recendy published and is available.
After more than two years of preparation, Dr. Margaret B. Ballard, an
emeritus member of the department of obstetrics and gynecology and an
alumna of the school, has published an excellent history or genealogy of
the entire University of Maryland which of course includes the School of
Medicine.
The Medical Alumni Association is acting as agent for the publication
and copies of the book may be purchased through the Medical Alumni
Association at a cost of $7.50 each. The book may be purchased also
directly through Dr. Margaret B. Ballard, Union, West Virginia.
Please send me copies of Return this coupon to:
A UnUersityls Born ^^i^^, ^,„^„i O^^^
by Margaret B. Ballard, M.D.
at $7..50 each University of Maryland
Name Lombard & Greene Streets
Address Baltimore, Md. 21201
Vol. 51. No. 1
'M
U. OF M. ALUMNI AT ANNUAL MEETING OF SOUTHERN MEDICAL ASSOCIATION
Twenty-one medical school alumni got
together in the Grand Ballroom of the Rice
Hotel on the occasion of the Southern
Medical Association convention held in
Houston, Texas the first week in November,
1965.
Among those present were Dr. and Mrs.
F. A. Holden of Baltimore, Dr. C. Martin
Rhode, Class of 1940 of Augusta, Georgia,
Dr. and Mrs. H. M. Robinson, of Baltimore,
Dr. and Mrs. R. C. V. Robinson of Balti-
more, Dr. and Mrs. L. C. Dobihal, Dr. and
Mrs. W. P. Beckner, Dr. and Mrs. Jack
Sugar, Dr. Mortimer Williams, Dr. and Mrs.
Stuart Brown, Dr. John Wagner, Dr. George
Peer of the Class of 1938, Dr. James Cianos
and Dr. and Mrs. John J. Bunting of the
Class of 1938. The Buntings acted as local
hosts.
Dr. R. C. V. Robinson, Councilor for
Maryland to the Southern Medical Associa-
tion, brought as his guest this year, Mr.
Richard M. Susel of the University of Mary-
land Class of 1966. Mr. Susel represented
the University of Maryland School of Medi-
cine at the Convention. Each year the
Southern Medical Association invites a
student representative from each medical
school throughout the South.
PRESIDENT'S LETTER (Cent.)
Annually the Medical Alumni Association chooses a worthy alumnus to receive the
Honor Award. The recipient of the 1966 Honor Award is honored, respected, and
loved by all of us and I know of no one more worthy to receive it. He is Dr. T. Nelson
Carey, one of the University's most diligent and loyal supporters for the past 42 years.
I am sure that all of the alumni will be happy in the choice which has been made and
will want to greet Dr. Carey on Alumni Day.
I think it is important to again mention here that the Maryland Medical Reunion
will be held this year on May 5, 6 and 7, 1966. Please make note that this is ap-
pro.ximately one month earlier than the usual Annual Alumni Day activities, and the
date of the meeting coincides with the original Maryland Medical Reunion in 1964 which
was so successful. We expect between five and six hundred returning alumni to attend,
so keep the dates in mind and when you receive your preregistration slip mail it in im-
mediately so that reservations can be made for you for the luncheon and for the alumni
banquet. We look forward this year to seeing the largest alumni turn-out in the history
of the University of Maryland School of Medicine.
C. PARKE SCARBOROUGH, M.D.
President
January, 1966
Alumni Day May 6, 1966
Alumni Reunion Combined
with Meeting of University
Hospital Medical Associations
The president and directors of the Medical
Alumni Association have announced a three
day scientific session, on the campus of the
School of Medicine, May 5, 6 and 7, 1966.
Events will begin on Thursday, May 5th
with a reception for all at the Caswell Room
of the Lord Baltimore Hotel from 8:30
to 10 P.M.
Alumni Day will begin officially at 8 a.m.
May 6, with registration in the Health
Sciences Library. This will be followed by
a General Assembly at 8:45 A.M. This
will be followed by Scientific Sessions and
the morning will be concluded by the an-
nual business meeting of the Medical
Alumni Association which will be held
in Chemical Hall at 1 1 o'clock concluding
at noon.
Dr. T. Nelson Carey to Receive
Alumni Award and Gold Key
The Medical Alumni Association has
nominated Dr. T. Nelson Carey, professor
of clinical medicine in the school of medi-
cine, as the recipient of the Alumni Award
and Gold Key. Dr. Carey, known to two
generations of medical students and faculty
and a long time active member of the staff
of the University Hospital, will receive the
honor from the hands of Dr. C. Parke
Scarborough, president of the Medical
Alumni Association, at appropriate cere-
monies in Chemical Hall following con-
clusion of the annual business meeting.
Dr. Carey is a native of Baltimore and an
alumnus of Loyola College in the Class of
1923. He completed his studies for the
degree of medicine at the University of
DR. T. NELSON CAREY
Maryland, graduating in the Class of 1927,
following which he served his rotating in-
ternship at the Mercy Hospital, becoming
chief resident in medicine in 1929. This was
followed by a post-doctoral fellowship at
the Johns Hopkins Hospital in 1930. He
immediately entered active practice of medi-
cine and teaching, serving also as student
health physician at the school of medicine.
His intense application to clinical medicine
soon became evident and Dr. Carey rapidly
became known as a brilliant analyst of
complex medical problems and an able
consultant. He was obviously at home with
and expressed delight in the application of
his talents to the solution of complex
medical problems. He became the doctor's
doctor not only as a consultant but as the
personal physician to many of the staff
of the school of medicine and other hospitals
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
throughout the city. His progress in the
department of medicine was steady and dur-
ing World War II it was Nelson Carey who
shouldered an overwhelming load of clinical
teaching, literally serving as the unnamed
professor of an overloaded and understaffed
department. This challenge he met despite
physical handicaps which prevented his
entry into the military service.
Following the war he returned to his
active practice as a consultant but was again
called to serve as acting head of the de-
partment of medicine for a year during
which time Dr. Maurice Pincoffs served as
a special assistant to the President of the
University. He then returned to active
clinical practice.
He is author of a number of scientific
publications relating to infectious diseases,
drug toxicity, and many other important
contributions.
During his undergraduate days he was
the recipient of a Hitchcock Scholarship, the
Randolph Winslow Scholarship and the
Faculty Gold Medal for the highest average
at graduation. He is a member of the
American Board of Internal Medicine, a
member of the American Medical Associa-
tion and the American College of Physicians.
Trul\', this brilliant man, busy internist,
consultant, teacher, friend; this keen,
anaUtical medical mind, exceptionally
brilliant, unquestionably frank and always
enthusiastic is the man who on this oc-
casion of the annual meeting of the Medical
Alumni Association is selected to receive
the highest accolade of the association, the
Gold Medal and Honor Award for outstand-
ing contributions to medicine and dis-
tinguished service to mankind.
Alumni to Present an
Interesting Evening Program
Following the conclusion of the business
meeting and the presentation of the Honor
Award, a luncheon will be held in the
gymnasium of the Psychiatric Building be-
ginning at approximately 12:30 P.M. This
will be followed by a reception for the 50
year honor graduates to be held in the
HOTEL ACCOMMODATIONS
This information is provided for your convenience. Please make your reservations directly
with the hotel of your choice.
Number Two Persons Two Persons
of rooms Single Rate Double Twin Telephone
Lord Baltimore Hotel 700 $ 9.50-$16.50 $13.00-$19.50 $15.00-$21.OO LE 9-8400
Baltimore & Hanover Sts.
Baltimore, Md. 21203
Sheraton-Belvedere 250 $ 9.85-$13.00 $13.85-$17.00 $17.00-$18.85 MU 5-1000
Charles & Chase Sts. $14.85
Baltimore, Md. 21202
Emerson Hotel 400 $ 8.50-$ 12.00 $13. 00-$ 1 8.00 $13. 00-$ 18.00 MU 5-4400
Baltimore & Calvert Sts.
Baltimore, Md. 21203
Holiday Inn— Downtown 254 $13.00-$14.00 $17.00-$18.00 $17.00-$18.00 685-2500
Howard & Lombard Sts.
Baltimore, Md. 21203
Mohawk Motel
1701 Russell St.
Baltimore, Md. 21230
126 $ 9.50-$1050 $14.50
$14.50
837-2400
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Florentine Room of the Lord Baltimore
Hotel. The annual banquet of the associa-
tion will be held at the Lord Baltimore at
6:30 P.M. Friday, May 6, 1966. An at-
tractive program has been prepared by the
program committee headed by Dr. John
O. Sharrett.
It is expected that copies of the com-
plete program of the University Hospital
Medical and Surgical Association as well
as that of the Alumni Association will be
sent individually to the membership.
Those physicians desiring to make a
reservation for the entire day might find it
convenient to use the information on page
xxlx.
Anniversary Reunion Class
Captains
The anniversary reunion classes should
contact their Class Captains:
Class of 1916, Henry F. Buettner and
George A. Bawden, co-captains.
Class of 1921, Albert Jaffe, Captain.
Class of 1926, John Askin, and W. C.
Merkel, co-captains.
Class of 1931, Emmanuel A. Schimunek,
Captain.
Class of 1936, Gibson J. Wells.
Class of 1941, Pierson M. Checkert.
Class of 1946, Joseph B. Workman.
Class of 1951, Wm. G. Esmond.
Class of 1956, Joseph S. McLaughlin.
Class of 1961, Michael A. Oldstone, Captain.
CLASS OF 1916— 50TH ANNIVERSARY
Richard T. Arnest, M.D.
Hague, Va. 22469
Bartus T. Baggott, M.D.
3812 Greenmount Ave., Baltimore, Md.
21218
George A. Bawden, M.D.
1110 The Broadview, Baltimore, Md. 21210
Edward H. Bensen, M.D.
204 E. Joppa, Hampton House Apt., 204,
Baltimore, Md. 21204
Eufemio N. Boccanegra-Lopez
1 Espana Way, Panama, R.P. 00100
Thomas Latham Bray, M.D.
Bo.x 576, Plymouth, N. C. 27962
Charles R. Brooke, M.D.
VA Hosp., East Orange, N. J. 07019
B. Bruce Brumbaugh, M.D.
5609 Main, Elkridge, Md. 21227
Henry F. Buettner, M.D.
5005 Edmondson Ave., Baltimore, Md.
~> 1229
Honorio F. Carrasquillo, M.D.
47 Victor Pradera, Madrid, Spain 00100
Michael Edward Cavallo, M.D.
265 Lafayette St., N. Y., N. Y. 10012
James Jennings Chandler, M.D.
132 N. Washington St., Sumter, S. C. 29150
Lucien Romeo Chaput, M.D.
3 Washington Sq., Haverhill, Mass. 01830
Wm. J. Dillon, M.D.
162 Maple St.
Springfield, Mass. 01105
Israel J. Feinglos, M.D.
2002 E. Pratt St., Baltimore, Md. 21231
Wm. T. Ferneyhough, M.D.
2021/2 South Scales, Reidsville, N. C. 27320
Wm. H. Flynn, M.D.
126 Main St., Bristol, Conn. 06010
Raymond K. Foxwell, M.D.
4103 N. 4th, Arlington, Va. 22203
Fred T. Foard, M.D.
701 Beaver Dam Rd., Raleigh, N. C. 27607
Harry Goldmann, M.D.
7121 Pk. Hghts. Ave., Baltimore, Md. 21215
Bowers Hewitt Growt, M.D.
Med. Ctr., Addison, Mich. 49220
Humphrey W. Gvv^nn, M.D.
320 N. Magnolia, Orlando, Fla. 32802
John Roy Hege, M.D.
905 Martin Drive, Concord, N. C. 28025
Charles H. Lupton, M.D.
Box 9658, Norfolk, Va. 23505
George McLean, M.D.
Med. Arts Bldg., Bahimore, Md. 20101
Francis J. Mejias, M.D.
552 Miramar Ave.
Santurce, P.R. 00908
Vol. 51, No. 1
ALUMS'I ASSOCIATION SECTION
A. B. Nevling, M.D.
P.O. Box 558, Rochester, Minn. 55902
Frank Peter Nicholson, M.D.
301 Boston Blvd., Sea Girt, N. J. 08750
Robert H. Noell, M.D.
207 Academy St., Roxboro, N. C. 27573
Vincent J. Oddo, M.D.
65 S. Hill Dr., Cranston, R. I. 02910
Gonzaio O'Neill, M.D.
410 Prospect St., E. Orange, N. J. 07017
Guy R. Post, M.D.
1 1 16 S. Park Dr., Fairmount, W. Va. 26554
Charles A. Reifschneider, M.D.
104 W. Madison St., Baltimore, Md. 20101
Francis F. Ruzicka, M.D.
800 N. Patterson Pk., Baltimore, Md. 21224
Wilbur Fiske Shirkey, Jr., M.D.
301 Atlas Bldg., Charleston, W. Va. 25301
Harold Milton Stein, M.D.
227 W. Broadway, Paterson, N. J. 07522
Carl M. Van Poole, M.D.
Mt. Airy, Md. 21771
Maurice C. Wentz, M.D.
455 W. Market St., York, Pa. 17404
Wm. Frederick Williams, M.D.
122 S. Center St., Cumberland, Md. 21502
CLASS OF 1921— 45TH ANNIVERSARY
Bruce Barnes, M.D.
328 High St., Seaford, Del. 19973
Carl Fisher Benson, M.D.
5111 York Rd., Balto., Md.
John R. Bernardo, M.D.
198 High St., Bristol, R. I. 02809
Vincent Bonfiglia, M.D.
2252 S. Bronson, Los Angeles, Calif. 90018
Earl E. Broadrup, M.D.
202 Virginia Ave., Cumberland, Md. 21503
Oscar Costa-Mandry, M.D.
Box 1730 Hato Rey, San Juan, P. R. 00919
Samuel H. Culver, M.D.
5812 Locklea Rd., Baltimore, Md. 21209
Herman J. Dorf, M.D.
7404 Liberty Rd., Baltimore, Md. 21207
Charles Frederick Fisher, M.D.
321 W. Main St., Clarksburg, W. Va. 26301
Leon Freedom, M.D.
1031 St. Paul St., Baltimore, Md. 21202
John Willis Guyton, M.D.
3961 Greenmount Ave., Baltimore, Md.
21218
Albert Jaffe, M.D.
130 Slade Ave., Apt. 1202, Baltimore, Md.
21208
George R. Joyner, M.D.
133 Chestnut St., Suffolk, Va. 23434
Arley Von McCoy, M.D.
2207 National Rd., Wheeling, W. Va. 26002
Thomas Rutter O'Rourk, M.D.
104 W. Madison St., Baltimore, Md. 21201
Frank Anthony Pacienza, M.D.
Washington Apt., 700 N. Charles St., Balti-
more, Md. 21201
Moses Paulson, M.D.
11 E. Chase St., Baltimore, Md. 21218
Edgar Allen Poe Peters, M.D.
394 Bergen Ave., Jersey City, N. J. 07304
Harold C. Pillsbury, M.D.
1800 N. Charles St., Baltimore, Md. 21201
Joseph Pokorny, M.D.
2200 E. Madison St., Baltimore, Md. 21205
N. Alfredo Quinones, M.D.
717 Paz St., Santurce, P. R. 00907
Francis Albert Reynolds, M.D.
43 Cottage St., Athol, Mass. 01331
Harold A. Romilly, M.D.
16701 Seneca Ave., Lakewood, Ohio 44107
Fred C. Sabin, M.D.
28 Salisbury, Little Falls, N. Y. 13365
Solomon Sherman, M.D.
2424 Eutaw PL, Baltimore, Md. 21217
Felix S. Shubert, M.D.
3926 State St., Erie, Pa. 16508
John Valentine Szczerbicki, M.D.
1802 Eastern Ave., Baltimore, Md. 21231
Louis M. Timko, M.D.
3015 Ripley Rd., Cleveland, Ohio 44120
Herman E. Wagner, M.D.
Box 824, Atlantic City, N. J. 08404
Wm. Ferdinand Weinkauf, M.D.
Corunna, Mich. 48817
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
George Edward Wells, M.D.
4100 Edmondson Ave., Baltimore, Md.
21229
Mortimer Harry Williams, M.D.
711 Med. Arts Bldg., Roanoke, Va. 24011
CLASS OF 1926— 40TH ANNIVERSARY
Harry Anker, M.D.
20569 California St., Woodland Hills, Calif.
91364
John Askin, M.D.
1401 Reisterstown Rd., Baltimore, Md.
21208
Margaret B. Ballard, M.D.
Old Hundred, Union, West Va. 24983
Jack H. Beachley, M.D.
221 W. Washington, Hagerstown, Md.
21740
Warren Elwood Calvin, M.D.
1215 4th Ave., Seattle, Wash. 98101
Antonio F. D'Angelo, M.D.
99 State St., Bristol, R. I. 02809
Henry DeVincentis, M.D.
285 Henry St., Orange, N. J. 07050
Hillel Elias Diamond, M.D.
1777 Grand Concourse, Bronx, N. Y. 10453
Frank R. DiPaula, M.D.
204 Court St., Binghamton, N. Y. 13901
Newman Houghton Dyer, M.D.
1800 Washington St., E., Charleston, W. Va.
25311
Paul Eanet, M.D.
6727 16th St., N.W., Washington, D. C.
20012
Charles William Edmonds, M.D.
614 Hastings Rd., Baltimore, Md. 21204
Julian C. Elliott, M.D.
Box 315, Oxford, N. C. 27565
Harold Herman Freedman, M.D.
63 W. Main St., Freehold, N. J. 07728
Arthur N. Freuder, M.D.
365 Parkside Ave., Brooklyn, N. Y. 11226
Isadore E. Gerber, M. D.
1095 Park Ave., N. Y., N. Y. 10028
David M. Helfond, M.D.
81-27 88th St., Brooklyn, N. Y. 11227
Nevins B. Hendrix, M.D.
122 S. Maple Ave., Martinsburg, W. Va.
25401
Calvin Hyman, M.D.
2500 Eutaw PI., Bahimore, Md. 21217
Jacob R. Jensen, M.D.
The Fenwick Apt., 303, 6101 Loch Raven
Blvd., Baltimore, Md. 21212
Philip Johnson, M.D.
Deveny Bldg., Fairmont, W. Va. 26554
Meyer S. Jolson, M.D.
531 Scott St., Covington, Ky. 41011
Alphonse J. Knapp, M.D.
208 Little Bldg., E. Liverpool, Ohio 43920
John A. Krosnoff, M.D.
909 Main St., Bentleyville, Pa. 15314
Louis T. Lavy, M.D.
1844 W. North Ave., Baltimore, Md. 21217
Hyman Edmund Levin, M.D.
3640 Fords Lane, Baltimore, Md. 21215
L Leonard Levin, M.D.
322 Broadway Bldg., Lorain, Ohio 44052
Joseph Levin, M.D.
831 S. 13th St., Newark, N. J. 07108
Wm. F. E. Loftin, M.D. (Capt, USN ret'd.)
410 Willow St., Marion N. C. 28752
Lloyd U. Lumpkin, M.D.
918 E. Las Olas Blvd., Ft. Lauderdale, Fla.
33301
Walter C. Merkel, M.D.
Union Mem. Hosp., Baltimore, Md. 21218
Harry G. Miller, M.D.
2060 Anthony Ave., Bronx, N. Y. 10457
Albert F. Moriconi, M.D.
438 Hamilton Ave., Trenton, N. J. 08609
Wm. C. Polsue, M.D.
Med. Arts Bldg., Charleston, W. Va. 25301
Arthur Rattenni, M.D.
1011 Smith Ave., Providence, R. I. 02908
Albert A. Rosenberg, M.D.
515 Sinclair St., McKeesport, Pa. 15132
Abraham S. Rothberg, M.D.
1 10 E. 90th St., N. Y., N. Y. 10028
David Sashin, M.D.
25 West 81st St., N. Y., N. Y. 10024
Paul Schenker, M.D.
2424 Eutaw PL, Baltimore, Md. 21217
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
David Schneider, M.D.
7813 Wise Ave., Baltimore, Md. 21222
William Schuman, M.D.
1701 Eutaw PI., Baltimore, Md. 21217
Ralph A. Schwartz, M.D.
101 Conant St., Hillside, N. J. 07205
-Arthur Anthony Scullion, M.D.
47 River\ie\v Ave., Cliffside Pk., N. J. 07010
Elizabeth Sherman, M.D.
P.O. Box 114, Front Royal, Va. 22630
Frank Spano, M.D.
320 47th St., Union City, N. J. 07087
Mourice L. Teitelbaum, M.D.
863 Eastern Pkwy.. Brooklyn, N. Y. 11213
Max Trubeck, M.D.
121 E. 60th St., N. Y., N. Y.' 10022
Samuel \\'einstein, M.D.
888 Eastern Pkv,y., Brooklyn, N. Y. 11213
Louis L. Weiss, M.D.
202 E. 51st St.. Brooklyn, N. Y. 11203
Louis J. Weseley, M.D.
600 E. ISth St., Brooklyn, N. Y. 11226
Guy Lorraine Whicker. M.D.
301 Prof. Bldg., Kannapolis, N. C. 28081
Samuel B. Wolfe, M.D.
2710 Bartol St., Baltimore, Md. 21209
CL.ASS OF 19.31— .3.5TH ANNIVERSARY
Philip Adalman, M.D.
87-10 37th Ave., Flushing, N. Y. 11372
David H. Andrew, M.D.
6905 Dunmanway, Baltimore, Md. 21222
Thomas M. Arnett, M.D.
2121 Pennsylvania, N.W., Washington, D. C.
20037
Paul C. Barton, M.D.
67 Union St., Worcester, Mass. 01608
Eugene Irving Baumgartner, M.D.
226 E. Alder St., Oakland, Md. 21550
H. I. Berman, M.D.
VA Hospital, Mellwood Ave. & Zorn Ave.,
Louisville, Ky. 40202
Wm. C. Boggs, M.D.
1325 Chaplihe St., Wheeling, W. Va. 26003
Arthur T. Brice, M.D.
JelTerson, Md. 21755
Bernard Brill. M.D.
24 8th Ave., Brooklyn, N. Y. 11217
John Brill, M.D.
910 N. 12th St., Philadelphia, Pa. 19123
Melvin B. Davis, M.D.
6800 Mornington Rd., Baltimore, Md. 21222
Joseph Francis Drenga, M.D.
1018 Green Acre Rd., Baltimore, Md. 21204
J. Wesley Edel, M.D.
4502 N. Charles St., Baltimore, Md. 21210
David S. Eisenberg, M.D.
72 South St., Auburn, N. Y. 13021
Samuel A. Feldman, M.D.
885 Park Ave., N. Y., N. Y. 10021
Arthur Stanley Feuer, M.D.
3099 Brighton 6th St., Brooklyn, N. Y.
11235
Isadore K. Grossman, M. D.
3409 Rosedale Rd., Baltimore, Md. 21215
Donald B. Grove, M.D.
Med. Bldg., Cumberland, Md. 21501
Rachel K. Gundry, M.D.
5002 Frederick Rd., Baltimore, Md. 21229
Marvin Ray Hannum, M.D.
54 W. Main St., Milan, Mich. 48160
Jos. W. Harris, M.D.
R.D. 1-8 Cecelia Rd., E. Syracuse, N. Y.
13057
Raymond Fred'k. Helfrich, M.D.
1120 St. Paul St., Baltimore, Md. 21202
Reuben Hoffman, M.D.
846 W. 36th St., Baltimore, Md. 21211
Mark B. Hollander, M.D.
836 Park Ave., Baltimore, Md. 21201
Kent Maidlow Hornbrook, M.D.
New Martinsville, W. Va. 26155
Samuel M. Jacobson, M.D.
50 Pershing St., Cumberland, Md. 21502
Frank H. Jaklitsch, M.D.
1048 Old Country Rd., Westbury, L. I.,
N. Y. 11590
Carl D. F. Jensen, M.D.
1601 16th Ave., Seattle, Wash. 98122
Page Covington Jett, M.D.
Prince Frederick, Md. 20678
Januarx, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Arthur F. Jones, M.D.
Garrett Co. Health Dept., Oakland, Md.
21550
Abraham Karger, M.D.
2015 Grand Concourse, Bronx, N. Y. 10453
Max Kaufman, M.D.
21-51 75th St., Flushing, N. Y. 11372
Walter J. Keefe, M.D.
350 Farmington Ave., Hartford, Conn.
06105
John F. Kilgus, Jr., M.D.
State Office Bldg., 165 Capitol Ave., Hart-
ford, Conn. 06115
Walter Kohn, M.D.
102 E. Fort Ave., Baltimore, Md. 21230
Jerome L. Krieger, M.D.
4024 6th Ave., Brooklyn, N.Y. 11232
Harry Lachman, M.D.
101 California Ave., Santa Monica, Calif.
90403
Vernon Langeluttig, M.D.
Mo. St. Sanatorium, Mt. Vernon, Mo. 65712
Alston Gordon Lanham, M.D.
Ronceverte, W. Va. 24970
Philip Lerner, M.D.
2 E. Read St., Baltimore, Md. 21202
Sidney Starr Leshine, M.D.
114-21 38th Ave., Flushing, L. I., N. Y.
11354
David R. Levine, M.D.
488 E. 18th St., Brooklyn, N. Y. 1 1226
Thomas Adrian Martin, M.D.
1300 Brookside Dr., Raleigh, N. C. 27604
John F. Masterson, M.D.
98 Myrtle Ave., Irvington, N. J. 07111
Leo M. Meyer, M.D.
Long Island Jewish Hosp. — Triboro Hosp.,
82-68 164th St., Jamaica, N. Y. 11432
Clarence F. Morrison, M.D.
Sutton, W. Va. 26601
Waldo B. Moyers, M.D.
3503 Perry St., Mt. Rainier, Md. 20822
Richard L. Murphy, M.D.
922 Elm St., Manchester, N. H. 03101
Leo S. Palitz, M.D.
31 W. 10thSt.,N. Y., N. Y. 10011
Manuel Rodriquez-Ema. M.D.
421 Tapia St., Santurce, P. R. 00915
Robert F. Rohm, M.D.
G7 MC Bldg., 1501 Locust St.. Pittsburgh,
Pa. 15219
Benjamin B. Rosenberg, M.D.
1070 E. New York Ave., Brooklyn, N. Y.
11212
John K. Rozum, M.D.
4100 Red Rd., Miami. Fla. 33155
Emanuel A. Schimunek, M.D.
842 So. East Ave., Baltimore, Md. 21224
Wm. Seabold, M.D.
134 W. Lanvale Dr., Baltimore, Md. 21217
Herman Harold Seidman, M.D.
760 Hunts Pt. Ave., Bronx, N. Y. 10474
Harry S. Shelley, M.D.
Vet. Adm. Hosp., Nashville, Tenn. 37203
Arthur G. Siwinski, M.D.
836 Park Ave., Baltimore, Md. 21201
Michael J. Skovron, M.D.
716 Sassafras St., Erie, Pa. 16501
Marvin L. Slate, M.D.
204 Boulevard, High Point, N. C. 27262
Alexander SlavcofT, M.D.
701 N. 2nd St., Harirsburg, Pa. 17102
Solomon Smith, M.D.
610 Gist Ave., Baltimore, Md. 21215
Russell A. Stevens, M.D.
158 S. Franklin St., Wilkes-Barre, Pa. 18701
Robert B. Taylor, M.D.
700 Cathedral St., Baltimore, Md. 21201
W. Alfred Van Ormer, M.D.
Med. Bldg., 122 S. Centre St., Cumberland,
Md. 21502
Harold C. Whims, M.D.
County Health Dept., Ashboro, N. C. 27203
Henry Wigderson, M.D.
162-05 89th St., Jamaica, N. Y. 11432
CL.\SS OF 1936— 30TH ANNIVERSARY
Abraham Louis Batalion, M.D.
301 Fair St., Middlebourne, W. Va. 26149
Milton Bernstein, M.D.
3202 Taney Rd., Baltimore, Md. 21215
E. Roland Bieren, M.D.
6416 Arlington Blvd., Falls Church, Va.
22044
Vol. 51, No. 1
ALUMXI ASSOCIATION SECTION
Dan George Bierer, M.D.
II Gransburg St., Delniont, Pa. 15626
Harry C. Bowie, M.D.
926 St. Paul St., Baltimore, Md. 21202
Irving Burka, M.D.
4400 Conn. Ave., N.W., Washington. D. C.
20008
Harold H. Burns, M.D.
8106 Harford Rd., Baltimore. Md. 21234
Jerome K.. Burton, M.D.
209 Main, Boise, Idaho 83702
Joseph E. Bush, M.D.
1 17 S. Main St., Hampstead, Md. 21074
George J. Coplin, M.D.
528 E. Jersey St., Elizabeth, N. J. 07206
Vladimir F. Ctibor, M.D.
School St., Califon, N. J. 07830
Leo M. Curtis, M.D.
8507 Lynwood PI., Chevy Chase, Md. 20015
Nachman Davidson, M.D.
6100 Pk. Hgts. Ave., Baltimore, Md. 21215
George H. Davis, M.D.
404 Hollen Rd.. Baltimore, Md. 21212
Se\mour R. Doehl, M.D.
230 W. Jersey St., Elizabeth, N. J. 07202
Stuart D. Dittmar, M.D.
473 Lincoln Way. E. Chambersburg, Pa.
17201
Darius McC. Dixon, M.D.
5504 Normandy PI., Baltimore, Md. 21210
Joseph Drozd, M.D.
240 S. Ann St., Baltimore, Md. 21231
Jerome Feldman, M.D.
20094 Mission Blvd., Hayward, Calif. 94541
Lester M. Fox, M.D.
104-14 85th Ave., Jamaica, L. I., N. Y.
11418
Michael G. Frich, M.D.
482 Carmel Pkwy., Corpus Christi, Texas
Marion H. Gillis, Jr., M.D.
206 Walnut St., Salisbury, Md. 21801
Harry S. Gimbel, M.D.
4605 Edmondson Ave., Baltimore, Md.
21229
Jesse W. Gordner, Jr., M.D.
410 Ferry St., Danville, Pa. 17821
Philip O. Gregory, M.D.
8 Commercial St., Boothbay Harbor, Maine
04538
Wm. Greifinger, M.D.
31 Lincoln Park, Newark, N.J. 07102
Jaye J. Grollman, M.D.
2026 R St., N.W., Washington, D. C. 20009
Benjamin Isaacs, M.D.
1261 E. Belvedere Ave., Baltimore, Md.
21212
C. Henry Jones, M.D.
707 N. Rebecca Ave., Scranton, Pa. 18504
Emory Ellsworth Jones, Jr., M.D.
Box 765, Mt. Hope, W. Va. 25880
Walter E. Karfgin, M.D.
1212 Southview Rd., Baltimore, Md. 21212
Saul Karpel, M.D.
190 Montauk Ave., New London, Conn.
06320
Norman Kleiman, M.D.
3803 Edmondson Ave., Baltimore, Md.
21229
Howard T. Knobloch, M.D.
1102 Columbus Ave., Bay City, Michigan
48708
Louis J. Kolodner. M.D.
2502 Eutaw PL, Baltimore, Md. 21217
Raymond J. Lipkin, M.D.
Vet. Adm. Hosp., Little Rock, Ark. 72206
Robert M. Lowman, M.D.
789 Howard Ave., New Haven, Conn. 06504
Grant Lund, M.D.
201 N. 8th St., Las Vegas, Nev. 89101
W. Kenneth Mansfield, M.D.
2 E. Read St., Baltimore, Md. 21202
Louis Robert Maser, M.D.
2724 Smith Ave., Baltimore, Md. 21209
Hector C. McKnew, Jr., M.D.
20 E. Locust St., Newark, Ohio 43055
Eugene McNinch, M.D.
126 Walker Rd., Dover, Del. 19901
James Blessing Moran, M.D.
66 Fruit Hill Ave., Providence, R. I. 02909
James Patrick Moran, M.D.
150AdlerSt.,Coronado, Calif. 92118
Benjamin B. Moses, M.D.
448 N. Luzerne Ave., Baltimore, Md. 21224
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Joseph R. Myerovitz, M.D.
5145 Pk. Hgts. Ave., Baltimore, Md. 21215
Wm. Myers, M.D.
1230 Monterey St., Pittsburgh, Pa. 15212
Hansford Dorsey Nester, M.D.
314 E. Grand Ave., Eau Claire, Wise. 54701
Thomas A. Nester, M.D.
337 Main St., Wakefield, R. I. 02879
Morris J. Nicholson, M.D.
25 Bonad Rd., West Newton, Mass. 02165
Sigmund Roman Nowak, M.D.
408 S. Patterson Pk. Ave., Baltimore, Md.
21231
Richard Heber Pembroke, Jr., M.D.
209 E. Biddle St., Baltimore, Md. 21202
Salvatore Dante Pentecost, M.D.
75 Holton La., Essex Falls, N. J. 07021
Carl Pigman, M.D.
Box 390, Whitesburg, Ky. 41858
Samuel Marvin Reichel, M.D.
6020 Nicollet Ave., Minneapolis, Minn.
55419
Gregory N. Rochlin, M.D.
200 Brattle St., Cambridge, Mass. 02138
Ralph B. Roseman, M.D.
4164 N. 7th St., Philadelphia, Pa. 19140
Victor Rosenthal, M.D.
324 Merrick Ave., Merrick, N. Y. 11566
James D. Royster, M.D.
Elm St., Benson, N. C. 27504
George Peter Schmieler, M.D.
615 1st St., Canonsburg, Pa. 15317
George D. Selby, M.D.
1835 Eye St., N.W., Suite 201, Washington,
D. C. 20006
Lawrence Joseph Shimanek, M.D.
3711 Falls Rd., Baltimore, Md. 21211
Cyril Solomon, M.D.
109 E. 61st St., New York, N. Y. 10021
Matthew Serin, M.D.
611 E. Poplar, Stockton, Calif. 95202
David M. Spain, M.D.
3 Tyler Rd., Scarsdale, N. Y. 10585
Milton Honore Stapen, M.D.
760 Bushwick Ave., Brooklyn, N. Y. 11221
Joseph L. Stecher, M.D.
908 Delaney St., Orlando, Fla. 32806
Samuel Steinberg, M.D.
2822 N. 5th St., Philadelphia, Pa. 19133
Morris H. Stern, M.D.
471 Clifton Ave., Clifton, N. L 07011
Stuart Dos Passes Sunday, M.D.
201 E. 33rd St., Baltimore, Md. 21218
Isaac Terr, M.D.
1037 7th St., Las Vegas, N. M. 87701
Anthony Jos. Thomas, M.D.
4600 York Rd., Baltimore, Md. 21212
Lawrence M. Tierney, M.D.
246 Elm St., West Haven, Conn. 06516
Baxter Suttles Troutman, M.D.
Dula Hosp., Lenoir, N. C. 28645
George Louis Vieweg, Jr., M.D.
3 1 Pleasant Dr., Wheeling, W. Va. 26003
Daniel George Wehner, M.D.
101 W. Read St., Baltimore, Md. 21201
Jacob J. Weinstein, M.D.
1712 Eye St., N.W., Washington, D. C.
20006
Gibson J. Wells, M.D.
5618 St. Albans Way, Baltimore, Md. 21212
Daniel Wilfson, Jr., M.D.
5721 Pk. Hgts. Ave., Baltimore, Md. 21213
Arthur G. Wilkinson, M.D.
1 1 1 Sherman Ave., New Haven, Conn.
06511
C. Vernon Williamson, M.D.
Prof. Arts BIdg., 5550 Balto. Nat'l. Pike,
Baltimore, Md. 21228
Nathan Wolf, M.D.
126 Main St., Brawley, Calif. 92227
Charles Sidney Yavelow, M.D.
105 Stevens Ave., Mt. Vernon, N. Y. 10330
Joseph G. Zimring, M.D.
222 Riverside Blvd., Long Beach, N. Y.
11561
CLASS OF 1941— 25TH ANNIVERSARY
Aurora F. Alberti, M.D.
4740 Chevy Chase Dr., Chevy Chase, Md.
20015
Fred Alexander, M.D.
Pennsylvania Hosp., Philadelphia, Pa. 19107
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
Jerome C. Arnett, M.D.
Rowlesburg, W. Va. 26425
Charles P. Barnett, M.D.
798 Ave. E., Riverside. Pa. 17868
Julius Culpepper Brooks, M.D.
546 McCallie Ave., Chattanooga, Tenn.
37402
Wm. Ross Bundick, M.D.
940 Park Ave., Baltimore, Md. 21201
John M. Carter, M.D.
1216 6th Ave., Huntington, W. Va, 25701
Pierson M. Checket, M.D.
4024 Essex Rd.. Baltimore, Md. 21207
Carlos M. Chiques. M.D.
560 Trigo St., Miramar, Santurce, P. R.
00907
Charles Edgar Cloninger, M.D.
305 1st St. E., Conover, N. C. 28613
Richard A. Conlen, M.D.
640 Farragut Ave., Haddonfield, N. J. 08033
Leroy G. Cooper, M.D.
827 S. George St., York, Pa. 17403
Joseph Vincent Crecca, M.D.
551 Berkeley Ave., Orange, N. J. 07050
Gene A. Croce, M.D.
194 Waterman St., Providence, R. I. 02906
Dwight P. Cruikshank, III, M.D.
1911 Dudley Ave., Parkersburg, W. Va.
26102
John McC. Culler, M.D.
15 E. 2nd St., Frederick, Md. 21701
Miguel L. DeVincentis, M.D.
1202 St. Paul St., Baltimore, Md. 21202
Smilo Diez-Gutierrez, M.D.
6 Pedro Arroyo St., Orocovis, P. R. 00720
Anthony DiPaula, M.D.
5301 Harford Rd., Baltimore, Md. 21214
John Esnard, M.D.
c/o NACC Bo.x 9, APO 63, San Francisco,
Calif. 96263
Edward L. Frey, Jr., M.D.
4605 Edmondson Ave., Baltimore, Md.
21229
Julius Gelber, M.D.
1514 Union St., Schenectady, N. Y. 12309
Wm. Goodman, M.D.
1334 Sulphur' Sp. Rd., Baltimore, Md. 21227
Theodore Joseph Graziano, M.D.
4019 Alameda Blvd., Baltimore, Md. 21218
Thomas A. Hcdrick, M.D.
338 Lincoln St., Johnstown, Pa. 15901
Newton W. Hershner, Jr., M.D.
211 W. Main St., Mechanicsburg, Pa. 17055
Asher Hollander, M.D.
3427 Johnson St., Hollywood, Fla. 33021
Lorman L. Hoopes, M.D.
315 E. MainSt., Minot, N. Dak. 58701
Pearl Huffman Scholz, M.D.
1 1 E. Chase St., Baltimore, Md. 21202
James Stanley Hunter, Jr., M.D.
1133 College Ave., Manhattan, Kansas
66502
Vita R. Jaffe, M.D.
5079 Bradley Blvd., Chevy Chase, Md.
20015
Norval Foard Kemp, M.D.
106 Sherman PI., Jersey City, N. J. 07307
Kenneth Krulevitz, M.D.
3306 Claran Rd., Baltimore, Md. 21215
Frank E. Lach, M.D.
1 8 1 Edwards St., New Haven, Conn. 065 1 1
Franklin Leslie, M.D.
302 E. 33rd St., Baltimore, Md. 21218
Jose S. Licha, M.D.
Doctors Hosp., Stop 20, San Juan, P. R.
00915
Thomas F. Lusby, M.D.
824 Buckingham Rd., Cumberland, Md.
21502
Raymond Malouf, M.D.
52 N. 1st East St., Logan, Utah 84321
Jacob B. Mandel, M.D.
HON. Y. Ave., Brooklyn, N. Y. 11216
Wm. A. Mitchell, M.D.
1 107 Ellis Ave., Lufkin, Texas 75901
Jose G. Molinari, M.D.
16 Palo Seco Rd., Bay View, Catano, P. R.
00632
Margaret E. Morgan, M.D.
3400 N. Meridian, Indianapolis, Ind. 46208
Felix R. Morris, M.D.
953 E. Main St., Bridgeport, Conn. 06608
Wm. Herbert Morrison, M.D.
3 Kinship Rd., Baltimore, Md. 21222
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
James J. Nolan, M.D.
416 Kensington Rd., Baltimore, Md. 21229
Miguel Novoa-Caballero, M.D.
18 Int. Rumirea St., Caguas, P. R. 00625
Ydalia Ortiz-Freeman, M.D.
Univ. of P. R., Sch. of Med., San Juan,
P. R. 00931
Margaret Virginia Palmer, M.D.
136 S. Washington St., Easton, Md. 21601
Benjamin Pasamanick, M.D.
410 W. 10th Ave., Columbus, O. 43210
Thompson Pearcy, M.D.
317 Atlas Bldg., Charleston, W. Va. 25301
Joshua M. Perman, M.D.
135 Central Prk. West, N. Y., N. Y. 10023
Irene Phrydas, M.D.
Emory Univ. Hosp., Atlanta, Ga. 30322
Charles E. Pruitt, M.D.
25 Petersville Rd., Brunswick, Md. 21716
Francis S. Renna, M.D.
20 Morris Ave., Morristovra, N. J. 07960
Walter Jones Revell, M.D.
Box 3, Louisville, Ga. 30434
Charles Richardson, Jr., M.D.
908 S. Main St., Bel Air, Md. 21014
Marion B. Richmond, M.D.
321 1 Wake Dr., Kensington, Md. 20795
Christian F. Richter, M.D.
1001 St. Paul St., Baltimore, Md. 21202
Clyde A. Rossberg, M.D.
2436 Washington Blvd., Baltimore, Md.
21230
Jonas S. Rosenberg, M.D.
1575 Gilpin St., Denver, Colo. 80218
Robert B. Sasscer, M.D.
Box 2150, Upper Marlboro, Md. 20870
Wm. Hamilton Sawyer, Jr., M.D.
126 Maiden Choice La., Baltimore, Md.
21228
John A. Scholl, M.D.
36 Hurley St., Belmont, Mass. 02178
Stanley E. Schwartz, M.D.
Dept. of Surgery, Kings Bridge VA Hosp.,
130 W. Kings Bridge Rd., Bronx, N. Y.
10468
Edwin L. Seigman, M.D.
Box 105 Bunn Dr., Rocky Mt., N. C. 27802
Edward P. Shannon, M.D.
714 Knoll Dr., San Carlos, Calif. 94070
Joseph C. Sheehan, M.D.
208 West St., Annapolis, Md. 21401
Elizabeth Brown Sherrill, M.D.
Beaver Dam Rd., Cockeysville, Md. 21030
Thomas C. Sims, M.D.
Longacre Med. Ctr., Longacre, W. Va.
25127
Benedict Skitarelic, M.D.
R. D. #9, Cumberland, Md. 21502
Tracy N. Spenser, Jr., M.D.
144 7th Ave., S. Charleston, W. Va. 25303
John S. Stevens, M.D.
1438 Park Ave., Bridgeport, Conn. 06604
Camille Mary Stonehille, M.D.
2823 Sheridan Rd., Evanston, 111. 60201
Webster M. Strayer, Jr., M.D.
2616 W. 102nd St., Inglewood, Calif. 90303
Raymond K. Thompson, M.D.
1125 N. Calvert St., Baltimore, Md. 21202
Richard W. Trevaskis, Jr., M.D.
220 Balto. Ave., Cumberland, Md. 21502
George J. Ulrich, M.D.
527 San Ysidro Rd., Santa Barbara, Calif.
93103
Edmund J. Virusky, M.D.
413N. MainSt.,Baxley, Ga. 31513
James H. Walker, M.D.
1323 Quarrier St., E. Charleston, W. Va.
25301
Lester Aubrey Wall, Jr., M.D.
4407 Underwood Rd., Baltimore, Md. 21218
Dayton O. Watkins, M.D.
5318 Annapolis Rd., Bladensburg, Md.
20710
John B. Wells, Jr., M.D.
306 Cedarcroft Rd., Baltimore, Md. 21212
Edwin F. Wilson, M.D.
235 Osborne Ave., Riverhead, L. I., N. Y.
11901
Kazuo Yanagisawa, M.D.
216E. 50thSt.,N. Y., N. Y. 10022
John David Young, Jr., M.D.
University Hosp. 21201
Kenneth L. Zierler, M.D.
601 N. Broadway, Baltimore, Md. 21205
Vol. 51. No. 1
ALU MM ASSOCIATION SECTION
CLASS OF 1946— 20TH ANNIVERSARY
Jesse H. Arnold, Jr., M.D.
400 Glenwood St., Kinston. N. C. 28501
Charles H. Audet, Jr., M.D.
3 2nd Ave., Waterbury, Conn. 06710
Jeanne Dorothy Audet, M.D.
Waterbury Rehab. Ctr., Waterbury, Conn.
06708
Robert Jos. Audet, M.D.
132 E. Mountain, Waterbury, Conn. 06706
Wm. J. Bannen, M.D.
Forest Park, Simpsonville, S. C. 29681
Robert E. Bauer, M.D.
Meridian Med. Bldg., 1680 Meridian Ave.,
Miami Beach, Fla. 33139
Walter J. Benavent, M.D.
Box 1854, Hato Rey, San Juan, P.R. 00919
Alfred Dement Bonifant, M.D.
Sandy Point, Md. 20860
Eli M. Brown, M.D.
13123 La Salle, Huntington Woods, Mich.
48070
Robert B. Brown, M.D.
120 E. Main St., Romney, W. Va. 26757
Louise P. Buckner, M.D.
R.D. # 2, Box 309 Altamont, N. Y. 12009
Harold V. Cano, M.D.
391 Main St., Box 436, Spotswood, N. J.
08884
Wm. F. Carr, M.D.
410 N. 2nd St., Harrisburg, Pa. 17101
Thomas W. Christopher, M.D.
46 Church St., Dedham, Mass. 02026
Sidney Clyman, M.D.
105 Stevens Ave., Mt. Vernon, N.Y. 10550
Francis I. Codd, M.D.
P.O. Box 627, Severna Pk., Maryland 21 146
Jerome Cohn, M.D.
1900 S. Atlantic Blvd., Montery Pk., Los
Angeles, Calif. 90022
Thomas B. Connor, M.D.
Univ. Hosp., Lombard & Greene Sts., Balti-
more, Md. 21201
Richard J. Cross, M.D.
104 W. Madison St., Baltimore, Md. 21201
Waiter L. Crouch, M.D.
1 002 Grace St., Wilmington, N.C. 28401
Jose Diaz-Carazo, M.D.
1475 Wilson Ave., Santurce, P. R. 00907
Joseph D'Antonio, M.D.
Church Home & Hosp., Baltimore, Md.
21231
Guy K. Driggs, M.D.
10335 N. Zangs Blvd., Dallas, Texas 75208
Vincent Offley Eareckson, Jr., M.D.
129 N.Washington St., Easton, Md. 21601
Herman L. Earnhardt, Jr., M.D.
2301 Fall Hill Ave., Fredericksburg, Va.
22401
James Lee Eavey, M.D.
1004 Beverly Rd., Rockledge, Fla. 32955
Jos. S. Fischer, M.D.
115 Redwood Dr., Roslyn, N. Y. 11576
Paul E. Frye, M.D.
1244 Sunsetview Dr., Akron, Ohio 44313
Samuel David Gaby, M.D.
2415 Diana Rd., Baltimore, Md. 21209
John R. Gamble, Jr., M.D.
Box 250, Lincolnton, N. C. 28092
Wm. D. Gentry, Jr., M.D.
Med. Arts Bldg., Baltimore, Md. 21201
James J. Gerlach, M.D.
4 E. Eager St., Baltimore, Md. 21202
Abraham A. Goetz, M.D.
125 South Dr., Mountain View, Calif. 94040
H. Wm. Gray, M.D.
4501 Connecticut, N.W., Washington, D. C.
20008
Duane L. Greenfield, M.D.
513 S. Main, Sioux Falls, S. D. 57102
Leland Jay Hansen, M.D.
Suite 3, 3875 Jackson St., Riverside, Calif.
92503
Henry C. Hardin, Jr., M.D.
25 S.E. 2nd Ave., Miami, Fla. 33131
John B. Harley, M.D.
Box 19, Rt. # 4, Morgan town, W. Va.
26501
Charles W. Hawkins, M.D.
744 McCallie Ave., Chattanooga, Tenn.
37402
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Charles A. Hefner, M.D.
2037 Crystal Sp. Ave., S.W., Roanoke, Va.
24014
Edwin O. Hendrickson, III, M.D.
Box 546, Truckee, Calif. 95734
Harry E. Hill, M.D.
8819 Reseda Blvd., Northridge, Calif. 91325
J. Poulson Hunter, M.D.
2131 E. 21st S., Salt Lake City, Utah 84109
Nathan B. Hyman, M.D.
6609 Reisterstown Rd., Baltimore, Md.
21215
E. R. Jennings, M.D.
4029 Riverside Dr., Brunswick, Ga. 31520
Harry G. R. Knapp, M.D.
2650 Thirteenth St., Boulder, Colo. 80302
Lawrence J. Knox, M.D.
RFD 6, Olney, 111. 62450
J. Howard Latimer, M.D.
3574 E. Cliff Dr., Salt Lake City, Utah
84117
Herbert J. Levickas, M.D.
1073 Maiden Choice La., Baltimore, Md.
21229
Allan Macht, M.D.
3414 Janellen Dr., Baltimore, Md. 21208
L. T. Maholick, M.D.
1327 Warren Wms. Rd., Columbus, Ga.
31901
Ray B. Markely, Jr., M.D.
707 Thornwood Ct., Baltimore, Md. 21234
Charles B. Marshall, Jr., M.D.
824th AF Disp.. APO 239, San Francisco,
Calif. 96239
George Y. Massenbury, Jr., M.D.
700 Spring St., Macon, Ga. 31201
Robert E. May, M.D.
5662 The Alameda, Baltimore, Md. 21212
George McElfatrick, M.D.
830 E. Belvedere Ave., Baltimore, Md.
21210
Thomas C. McPherson, M.D.
Mead Johnson Lab., Evansville, Indiana
47721
Clarence E. McWilliams, Jr., M.D.
Reisterstown & Cherry Hill Rds., Reisters-
town, Md. 21136
Joseph Mintzer, M.D.
221 Lake Ave., Saratoga Sp., N. Y. 12866
John A. Mitchell, M.D.
8 1 1 Park Ave., Baltimore, Md. 21201
John Morrison, M.D.
Norwich St. Hosp., Norwich, Conn. 06361
J. D. Nataro, M.D.
42 Bluegrass La., Levittown, N. Y. 1 1756
Pomeroy Nichols, Jr., M.D.
I021-15th St., Augusta, Ga. 30901
Ellsworth H. North, Jr., M.D.
R.D. # 1, Sunrise Dr., Industry, Pa. 15052
James S. O'Hare, M.D.
Travis CI., Jacksonville, Texas 75766
Wm. W. Orrison, M.D.
125 N. Fowler St., Meade, Kansas 67864
Lt. Col. H. Osborne
2011 Iverson St., S.E., Washington, D. C.
20031
A. J. Owen, M.D.
1200 E. Belvedere Ave., Baltimore,
21212
Md.
Wm. F. Park, M.D.
Howard Hill-Wits End, Wheeling, W. Va.
26003
Earl R. Paul, M.D.
36 Greene St., Cumberland, Md. 21502
Clemmer M. Peck, M.D.
430 Monterey St., Los Gatos, Calif. 95030
Lois I. Piatt, M.D.
2300 K St., N.W., Washington, D. C. 20037
J. C. Rawlins, M.D.
603 N. Willey St., Seaford, Del. 19973
Milton Reisch, M.D.
104 E. 40th St., N.Y.. N. Y. 10016
Ralph A. Reiter, M.D.
112 Bedford. Cumberland. Md. 21502
R. A. Riley, Jr., M.D.
95 Cathedral St., Annapolis, Md. 21401
James A. Roberts, M.D.
8907 Georgia Ave., Silver Spring, Md.
20910
R. C. Rossberg, M.D.
1660 S. Alameda St.
90021
Los Angeles, Calif.
Vol. 51. No. 1
ALUMNI ASSOCIATION SECTION
Sidney Sacks, M.D.
20525 N.E. 19th St., N. Miami Beach, Fia.
33162
J. A. Sewell, M.D.
920 Valentine Ct., Melbourne, Fla. 32901
Frank Shallenberger, Jr., M.D.
Craycroft Med. Ctr., Tucson, Ariz. 85716
David N. Sills, Jr., M.D.
1 1 S.E. Front St., Milford, Del. 19963
Lt. Col. E. P. Smith, Jr., M.D.
7650 S.W. 1 33rd St., Miami, Fla. 33 1 56
C. W. Stallard, Jr., M.D.
28 Shore Pk. Dr., Newport News, Va. 23602
Herbert Swindell, M.D.
USAF Hosp. HMR, Keesler AFB, Miss.
39534
Leon Toby, M.D.
1 1 1 N. Wabash Ave., Chicago, 111. 60602
James A. Vaughn, Jr., M.D.
5965 Ponce deLeon, Coral Gables, Fla.
33146
Elliott L. Weitzman, M.D.
68 E. 86th St., N. Y., N. Y. 10028
Irl Wentz. M.D.
911 W. Henderson St., Salisbury, N. C.
28144
Walter Mcllhaney Wolfe, Jr., M.D.
5th Sta. Hosp., APO 154, N. Y., N, Y.
09154
Joseph B. Workman. M.D.
162 Ligon Rd., RED 5, Ellicott City, Md.
21043
Alexander W. Young, Jr., M.D.
520 E. 64th St., N. Y., N. Y. 10021
Richard A. Young, M.D.
101 King St., Hagerstown, Md. 21740
CLASS OF 19.51— 1.5TH ANNIVERSARY
Law L. Ager, M.D.
1901 12th Ave., Birmingham, Ala. 35205
Robert K. Arthur, Jr., M.D.
318 Westwood Ave., High Point, N. C.
27262
John P. Barthel, M.D.
1911 1st Ave., S.E., Cedar Rapids, Iowa
52402
Earl M. Bcardsley, M.D.
207 Maryland Ave., Salisbury, Md. 21801
Arthur K. Bell, M.D.
I I 70 Sylvania Ave., Toledo, Ohio 43612
Joseph Bilder, Jr.. M.D.
1300 8th St., Wichita Falls, Texas 76301
Beverly R. Birley, M.D.
837 N.E. 20th Ave., Fort Lauderdale, Fla.
33304
Nancy Blades, M.D.
2141 Rollingridge La., Cincinnati, Ohio
45211
John Wesley Bossard, M.D.
1 1 1 Med. Ctr. Bldg., Ft. Wayne, Ind. 46802
John V. Brannon, M.D.
1 1 1 Center St., Bridgeport, W. Va. 26330
John R. Buell. Jr., M.D.
402 Main St., Laurel, Md. 20810
Russell L. Christopher, M.D.
26 South St., Pittsfield, Mass. 01202
Raymond Clemmens, M.D.
Univ. Hosp., Baltimore, Md. 21201
Dwight I. Coblentz, M.D.
5102 Roland Ave., Balto., Md. 21210
Kaohlin M. Coffman, M.D.
421 Broad St., Montoursviile, Pa. 17754
Solomon Cohen, M.D.
2425 Geary St., San Francisco, Cahf. 94115
Raymond Curanzy, M.D.
39 E. Maple St., Palmyra, Pa. 17078
Joseph Deckelbaum, M.D.
4017 Liberty Hgts. Ave., Baltimore, Md.
21207
Ernest A. Dettbarn, M.D.
Walkersville, Md. 21793
Leon Donner, M.D.
4023 Brookhill Rd., Baltimore, Md. 21215
Winston C. Dudley, M.D.
585 Winter St., S.E., Salem, Oregon 97301
George M. Dunn, M.D.
Box 127, Princess Anne, Md. 21853
Wm. Dunnagan, M.D.
800 Rusk St., Amarillo, Texas 79106
David E. Edwards, M.D.
RD 2, Box 238, Keyser, W. Va. 26726
Wm. H. Edwards, Jr., M.D.
100 E. Biddle St., Baltimore, Md. 21202
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Wm. G. Esmond, M.D.
537 Stamford Rd., Baltimore, Md. 21229
Otis D. Evans, Jr., M.D.
105 Grover St., Shelby, N. C. 28150
Charles K. Ferguson, M.D.
1953 Mears Ave., Cincinnati, Ohio 45230
Joseph C. Fitzgerald, M.D.
Med. Ctr., Pine Bluff Rd., Salisbury, Md.
21801
Rowland E. J. Fullilove, M.D.
Turkey Farm Rd., Chapel Hill, N. C. 27514
James P. Gallaher, M.D.
Med. Ctr., Salisbury, Md. 21801
Mario Garcia-Palmieri, M.D.
Univ. of P.R. Sch. of Med., San Juan. P. R.
00931
F. S. Gardner, Jr., M.D.
P.O. Box 351, Fayetteville, N. C. 28302
John B. Gates, M.D.
6095 N. Country Club Rd., Merced, Calif.
95340
Benjamin D. Gordon, M.D.
2875 Main St., Stratford, Conn. 06497
Doris M. Harris, M.D.
6010 Shenandoah Ave., Los Angeles, Calif.
90056
Frederick J. Hatem, M.D.
908 S. Washington, Havre de Grace, Md.
21078
Robert C. Hopkins, M.D.
216 Main St., Lake City, Pa. 16423
George J. Item, M.D.
lOOVi W. Market St., Orrville, Ohio 44667
Frederick M. Johnson, M.D.
Box 460, La Plata, Md. 20646
Wallace E. Johnson, M.D.
137 Main St.. Dayton, Ohio 45402
Paul E. Kaschel, M.D.
535 N. 105th St., Wauwatosa, Wise. 53213
Willard F. Kindt, M.D.
601 Hanover Ave., Allentown, Pa. 18103
David Kipnis, M.D.
St. Louis Children's Hosp., 500 S. Kings-
highway Blvd., St. Louis, Mo. 631 10
Harry L. Knipp, M.D.
4116 Edmondson Ave, Baltimore, Md.
21229
Howard C. Kramer, M.D.
242 Coldbrook, Lutherville-Timonium, Md.
21093
William E. Lamb, M.D.
Box 218, Jacksonville, Fla. 32218
Theodore R. Lanning, M.D.
955 Park Ave., N. Y., N. Y. 10028
Jack Liebman, M.D.
490 Post St., San Francisco, Calif. 94102
Leo H. Ley, Jr., M.D.
456 N. Center St., Cumberland, Md. 21502
Leonard Melvin Lister, M.D.
7121 ParkHgts. Ave., Baltimore, Md. 21215
James M. MacDonald, Jr., M.D.
4819 Santa Monica Ave., San Diego, Calif.
92107
Earl B. McFadden, M.D.
Mem. Hosp., Chatham Co., Savannah, Ga.
31404
John W. McFadden, M.D.
407 Tonawanda Trail, Hartville, Ohio 44632
Charles Mc Grady, M.D.
2701 Atlantic Blvd., Pompano Beach, Fla.
33060
Kathleen R. McGrady, M.D.
1919 Atlantic Blvd., Pompano Beach, Fla.
33060
Ricardo T. Mendez-Bryan, M.D.
Univ. Hosp., Rio Piedras, P. R. 00928
John S. Metcalf, Jr., M.D.
2425 Geary, San Francisco, Calif. 941 15
Robert S. Mosser, M.D.
902 Starbit Rd., Baltimore, Md. 21204
Arthur Z. Mutter, M.D.
78 Wolcott Rd., Chestnut Hill, Mass. 02167
Donald J. Myers, M.D.
608 Main St., Wintersville, Ohio 43953
Edward J. Nygen, M.D.
RD 5, Westminster, Md. 21 157
John Stambaugh Orth, M.D.
Air Force Hosp., Ft. Worth, Texas 76127
Douglas R. Packard, M.D.
Box 22, Clinton, N. C. 28328
F. Robert Perrila, M.D.
Suite 214-17 Med. Arts Bldg., Baltimore,
Md. 21201
Vol. 51, No. 1
ALUMM ASSOCIATION SECTION
Henry D. Perry, Jr., M.D.
6024 \V;ishington St., West Hollywood, Fla.
33023
Guy Reeser, Jr., M.D.
St. Michaels, Md. 21663
Henry G. Reeves, Jr., M.D.
Med. Ctr., Pine BlutT, Salisbury, Md.
Eugene B. Rex, M.D.
l.ankenau Med. Bldg., Philadelphia, Pa.
19131
Georgia M. Reynolds, M.D.
220 N.W. 68th Ave., Apt. 4, Plantation, Fla.
Aubrey D. Richardson
Univ. Hosp., Baltimore
M. J. Rombro, M.D.
805 Fuselage Ave., Baltimore, Md. 21220
H. S. Roland, Jr.. M.D.
Lee Med. Bldg., Richmond, Va. 23220
A. Saavedra-Amador, M.D.
Box 98, Hatillo, P. R. 00659
Arthur H. Schmale, Jr., M.D.
70 Bradford Rd., Rochester, N. Y. 14618
R. D. Scott, M.D.
2301 W. 1st St., Ft. Myers, Fla. 33901
J. T. Scully, M.D.
7 1 5 Johnson St., Gary, Ind. 46402
Wm. H. H. Shea, M.D.
USAF Office Surg. Gen., Washington, D. C.
20333
Samuel N. Sherry, M.D.
35 Robinson St., Cambridge, Mass. 02138
L. Dale Simmons, M.D.
201 PrintyBldg.
Clarksburg, W.Va. 26301
Edward M. Sipple, M.D.
Moore Mem. Hosp., Pinehurst, N. C. 28374
R. Kennedy Skipton, M.D.
4500 College Ave., College Park, Md. 20740
David Solomon, M.D.
2525 Eutaw PL. Baltimore, Md. 21217
John H. Stone, M.D.
Box 607, La Plata, Md. 20646
Julian T. Sutton, M.D.
Norfolk Gen. Hosp., Norfolk, Va. 23507
R. B. Tobias, M.D.
1615 Riverside Dr., Williamsport, Pa. 17707
H. L. Twigg, M.D.
Georgetown Univ. Hosp., Washington, D. C.
20007
M. M. Udel, M.D.
St. Luke's Hosp., N. Y., N. Y. 10025
R. J. Venrose, M.D.
9939 Pk. Ave., Sepulveda, Calif. 91343
Charles P. Watson, Jr., M.D.
New Martinsville, W. Va. 26135
R. D. Weekley, M.D.
Med. Eye Bldg.. Inc., 5370 Pearl Rd., Cleve-
land, Ohio 44129
Harvey P. Wheelwright, M.D.
2955 Harrison Blvd., Ogden, Utah 84403
C. R. Williams, M.D.
508 S. Washington St., Gettysburg, Pa.
17325
Shelly C. York, Jr., M.D.
400 Randolph St., Thomasville, N. C. 27360
Thomas L. York, M. D.
4541 Everhart, Corpus Christi, Texas 7841 1
CLASS OF 1956— lOTH ANNIVERSARY
George A. Abeshouse, M.D.
2504 Shellydale Dr., Baltimore, Md. 21209
John E. Adams, M.D.
18 Marbury Rd., Severna Pk., Md. 21 146
Robert T. Adkins, M.D.
Fruitland P.O., Fruitland, Md. 21826
Daniel G. Anderson, M.D.
1313 Taney Ave., Salisbury, Md. 21801
Henry A. Baer, M.D.
U. S. Naval Hosp., Corpus Christi, Texas
Lt. Stephen Barchet, M.C.
USN 568k77/2100 Naval Support Act.,
Navy #510, FPO, N. Y., N. Y.
Richard Belgrad, M.D.
8039 N. 8th Ave., Phoenix, Ariz. 85021
Frank Bellomo, M.D.
71 Smull Ave., Caldwell, N. J. 07006
Jerald H. Bennion, M.D.
911 Mark Ave., Salt Lake City, Utah 84106
Capt. Stanley M. Bialke, M.D.
8218 Wise. Ave., Bethesda, Md. 20014
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Morris L. Blue, M.D.
5816 Greenspring Ave., Baltimore, Md.
21209
H. F. Bongardt, Jr., M.D.
Duke Hosp., Durham, N. C. 27706
Ernest O. Brown, M.D.
3414 Duvall Ave., Baltimore, Md. 21216
Richard A. Burningham, M.D.
4040 Matheson Ave., Miami, Fla. 33133
James A. Burwell, M.D.
947 Oakwood Dr., Falls Church, Va. 22041
Robert J. Byrne, M.D.
1308 DeKalb St., Norristown, Pa. 19401
Theodore R. Carski, M.D.
Rt. 2, Box 1 05, Phoenix, Md. 2 1 1 3 1
James Castellano, M.D.
11311 Francis Ave., Baltimore, Md. 21227
James McA. Chase, Jr., M.D.
75 Westland Drive, Dover, Delaware 1 1901
Wm. Cohen, M.D.
3700 W. Rogers Ave., Baltimore, Md. 21215
Thomas H. Collawn, M.D.
500 Ellsworth Rd., Charlotte, N.C. 28207
David L. Davidson, M.D.
USA Hosp., Ft. Amador, C. Z. 00101
Evelyn Anna De La Vega, M.D.
44 McLelland Blvd., Brownsville, Texas
78520
James T. Dorsey, M.D.
910 Turner St., Emmaus, Pa. 18049
John D. Downing, Jr., M.D.
10700 Seminole Blvd., Largo, Fla. 33542
Ludwig J. Eglseder, M.D.
514 S. Tripp Ave., Easton, Md. 21601
James T. Estes, M.D.
915 19th St., N.W., Washington, D.C.
20006
Richard G. Farmer, M.D.
2020 E. 93rd St., Cleveland, Ohio 44106
Richard Finegold, M.D.
3600 Forbes Ave., Pittsburgh, Pa. 15213
Girard V. Foster, M.D.
84 Ladbroke Rd., London W. 11, England
Jorge A. Franco, M.D.
1090 Calle 5 Villa Navarez, Rio Piedras,
P. R. 00928
Marshall Franklin, M.D.
5 Elmcrest Terr., Norwalk, Conn. 06850
Edward D. Frohlich, M.D.
Research Div., Cleveland CI., Cleveland,
Ohio 44106
Alfred Wm. Grigoleit, M.D.
R.D. 2, Box 225, Havre de Grace, Md.
21078
J. Henry Hawkins, M.D.
900 Cottage Gr. Rd., Bloomfield, Conn.
06002
Robert N. Headley, M.D.
Dept. Med., Bowman Gray Sch., Winston-
Salem, N. C. 27103
Neil C. Henderson, M.D.
400 N.E. 44th St., Ft. Lauderdale, Fla.
33308
Major Webb. S. Hersperger, M.D.
Munson Army Hosp., Ft. Leavenworth,
Kansas 66027
Lee Hoffman, M.D.
Van Etten Hosp. Ctr.. Bronx, N. Y. 10461
Virgil R. Hooper, M.D.
718 Beach St., Flint, Mich. 48502
Ralph T. Hummel, M.D.
Box 309, Sedro Wolley, Washington 98224
Gilbert E. Hurwitz, M.D.
1800 Eye St., N.W., Washington, D. C.
20006
Daniel F. Johnston, M.D.
1504 Upshire Rd., Baltimore, Md. 21218
Albert V. Kanner, M.D.
1 10 E. Main St., Madison, Wise. 53703
Robert M. Kaplan, M.D.
Boston State Hosp.. Boston, Mass. 02124
Sheppard G. Kellam, M.D.
5805 Dorchester Ave., Chicago, 111. 60637
John E. Kelley, Jr., M.D.
173 Parkside Ave., Syracuse, N.Y. 13207
C. Herschel King, M.D.
3212 Sherbon Dr., Durham, N. C. 27707
Kenneth M. Klatt, M.D.
1300 Univ. Ave., Madison, Wise. 53715
Paul W. Knowles, M.D.
101 E. Furnish, Pendleton, Ore. 97801
ElmerC. Koller, Jr.,M.D.
S & E Pratt Hosp., Baltimore. Md. 21204
Vol. 51, No. 1
ALUMXI ASSOCIATIOX SECTION
Bernard Kramer, M.D.
153 S. Main St., Wallinglord, Conn. 064'):
H, Coleman Kramer, M.D.
6420 Adams Ave., Miami Beach. Fla. 33140
Sheldon Kress, M.D.
911 Balmoral Dr., Silver Spring, Md. 20903
Louis J. Lancaster, NLD.
355 N.W. Richmond Bch. Rd., Seattle,
Wash. 98177
Joseph G. Lanzi, M.D.
Elkton Med. Pk., Elkton, Md. 21921
Carl P. Laughlin, NLD.
31 16 Victoria Blvd., Hampton, Va. 32261
NLithew H. M. Lee, M.D.
79-04 150th St., Flushing, N. Y. 1 1367
Wni. A. Lemmert, M.D.
37 1 6 Swann Ave., Tampa, Fla. 33609
Betty L Libert, M.D.
Grand Central Sta., Box 3098, N. Y., N. Y.
1 000 1
John B. Littleton, M.D.
1515 Martin Blvd., Baltimore, Md. 21220
\Vm. T. Lloyd, M.D.
327 E. Main St., Newark, Del. 19712
Thomas A. Love, M.D.
14 W. Main St., Thurmont, Md. 21788
Gerald N. Maggrid, M.D.
Pikesville Med. Ctr., Baltimore, Md. 21208
Robert J. Mahon, M.D.
602 E. Joppa Rd., Baltimore, Md. 21204
Samuel J. Mangus, M.D.
Qtr. 2764, Ferguson Cir., Ft. Eustace, Va.
23604
Herbert M. Marton, M.D.
245 Engle St., Englewood, N. J. 07631
Joseph S. McLaughlin, M.D.
Clinical Ctr., NIH, Bethesda, Md. 20014
Robert G. Muth, M.D.
Kansas City Gen. Hosp., Kansas City, Mo.
64108
Richard I. Myers, M.D.
207 Franklin Ave., Silver Sp., Md. 20901
John F. Nowell, M.D.
Arlington Med. Bldg., Arlington, Va. 22207
Clark Lamont Osteen, M.D.
1 lA Md. Arts Ctr., Savannah, Ga. 31405
David A. Oursler, M.D.
1 I 18 St. Paul St., Baltimore, Md. 21202
\Vm. M. Palmer. M.D.
6700 Foothills Blvd., Oakland. Calif. 94605
Wilbur C. Pickett, Jr., M.D.
3714 Woodbine St., Chevy Chase, Md.
20015
Marvin S. Piatt, M.D.
4120 Silver St., S.E.. Albuquerque, N. Mex.
87108
Richard L. Plumb, M.D.
6303 S. Park Blvd., Houston, Texas 77021
Irvin P. Pollack, M.D.
4419 Falls Rd., Baltimore, Md. 21211
George E. Reahl, M.D.
804 Cathedral St., Baltimore, Md. 21201
Harold L Rodman, M.D.
1302-18th St., N.W., Washington, D. C.
20036
Harry Paul Ross, M.D.
203 N. Queen St., Chestertown, Md. 21620
Charles A. Sanislow, Jr., M.D.
804 Vance Rd., Midland, Mich. 48640
Gerald Schuster, M.D.
8812 Cameron St., Silver Spring, Md. 20910
Roy O. Shaub, M.D.
1 1 1 Sixth Ave., E. Twin Falls, Idaho 83301
Virginia Truitt Sherr, M.D.
Norristown St. Hosp., Norristown, Pa. 19401
Wm. A. Sinton, Jr., M.D.
102 Allegheny Ave., Baltimore, Md. 21204
James W. Skaggs, Jr., M.D.
1200 Blythe Blvd., Charlotte, N. C. 28203
Paul V. Slater, M.D.
Medical Center, Salisbury, Md. 21801
George T. Smith, M.D.
Desert Res. Inst., Univ. of Nev., Reno, Nev.
89502
George A. Sowell, M.D.
520 Pinehill Rd., N.W., Orangeburg, S. C.
29115
James J. Stovin, M.D.
45 Elm Ave., Metuchen, N. J. 08840
Robert G. Stuck, M.D.
Lake Ave., Wolcott, N. Y. 14590
Jaiiiiarv, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
H. E. Sturgeon, M.D.
5126 Princess A. Rd., Virginia Beach, Va.
23452
Albert L. Trucker, Jr., M.D.
Mtgmry. Dr., Santa Rosa, Calif. 95405
Edwin W. Whiteford, Jr., M.D.
Wheeler School Rd., Whiteford, Md. 21 160
John Z. Williams, M.D.
1350 Sundown Dr., Aurora, 111. 60506
Harry D. Wilson, Jr., M.D.
Adams-Stratton Rds., Williamstown, Mass.
01267
Robert Lee Wright, M.D.
207 Robinson Bldg., Elyria, Ohio 44035
CLASS OF 1961— 5TH ANNIVERSARY
Andres Acosta-Otero, M.D.
Univ. Hosp., Bahimore, Md. 21201
James R. Appleton. M.D.
531 Cortland Ave., Syracuse, N. Y. 13205
Neil R. Arbegast, M.D.
Methodist Hosp., Houston, Texas 77025
Nicholas R. Bachur, M.D.
Natl. Heart Inst. NIH, Bethesda, Md. 20014
George E. Bandy, M.D.
Univ. Mo. Med. Ctr., Columbia, Mo. 65201
Joseph C. Battaile, M.D.
Springfield St. Hosp., Sykesville, Md. 21784
Joseph W. Berkow, M.D.
J. H. Hosp., Baltimore, Md. 21205
Carl P. Berner, M.D.
Univ. Hosp., Baltimore, Md. 21201
Oscar H. Bing, M.D.
Georgetown Univ. Hosp., Washington, D. C.
20007
Myron B. Blum, M.D.
5720 Pimlico Rd., Baltimore, Md. 21209
Anthony R. Boccuti, M.D.
3198 Wrightsboro Rd., Apt. A, Augusta,
Ga. 30904
Thomas G. Breslin, M.D.
R. I. Hosp., 593 Eddy St., Providence, R. L
02902
John N. Browell, Jr., M.D.
H. Ford Hosp., Detroit, Mich. 48202
Joseph N. Brouillette, M.D.
H. Ford Hosp., Detroit, Mich. 48202
James C. Bulger, M.D.
Mercy Hosp., Baltimore, Md. 21202
Milton H. Buschman, Jr., M.D.
2511 W. Weaver Ave., Springfield, Md.
65804
Capt. Ronald L. Cain, M.D.
05708389, 13th USASA Field Sta., Box 44,
APO 210, N. Y., N. Y. 09210
James J. Cerda, M.D.
Univ. of Pa. Hosp., Philadelphia, Pa. 19104
Angela W. Clarke, M.D.
P.O. Box 1077, Palo Alto, Calif. 94302
Francis A. Clark, Jr., M.D.
Univ. Hosp., Baltimore, Md. 21201
John W. Clark, M.D.
Univ. Hosp., Baltimore, Md. 21201
Kenneth L. Cloninger, Jr., M.D.
524 Corran P., Franklin Lakes, N. J. 07417
Maurice M. Davidson, M.D.
New England Ctr. Hosp., Boston, Mass.
02111
Gregory Delli-Pizzi, M.D.
860 Madison Ave., Memphis, Tenn. 38103
Karl W. Davenport, M.D.
16710 N.E. 16th Place, Bellevue, Washing-
ton 16710
John N. Diacoyanis, M.D.
Univ. Hosp., Baltimore, Md. 21201
Wm. H. Dudney, M.D.
5092 Dartmouth, Westminster, Calif. 92683
Daniel J. Fall, M.D.
Mercy Hosp., Baltimore. Md. 21202
Grover Farrish, M.D.
200 Hartman Rd., Newton Center, Mass.
02159
Bernadine C. Faw, M.D.
923 St. Paul St., Baltimore, Md. 21202
Robert A. Fink, M.D.
Univ. of Chicago Clinic, 950 E. 59th St.,
Chicago, 111. 60637
Wm. R. Fleming, Jr., M.D.
8711 Geren Rd., Silver Spring, Md. 20901
Redwell K. Forbes, M.D.
Norfolk Gen. Hosp., Norfolk, Va. 23507
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
Carlos E. Girod, M.D.
P.O. Box 863. Hato Rev, P. R. 00919
Leonard W. Glass. M.D.
Univ. Hosp.. Baltimore. Md. 21201
Jay S. Goodman. M.D.
Vanderbilt Univ. Hosp.. Nashville, Tenn.
37203
Ronald L. Gutherlet. M.D.
USA Med. Service Gr.. APO 331. San
Francisco. Calif. 96431
Samuel H. Henck. M.D.
109 N. Washington St.. Carthage, N. Y.
13619
Robert L. Heymann. M.D.
Tripler Gen'l. Hosp.. APO 438, San Fran-
cisco. Calif. 96438
Gerald A. Hofkin. M.D.
6026 Green Meadow Pkwy., Baltimore, Md.
21209
Richard G. Holz, M.D.
809 Chapelgate La., Baltimore. Md. 21229
James L. Hooper. M.D.
3003 Ferndale PI., Kensington, Md. 20795
Carlos E. Ifarraguerri, M.D.
12 Palmasola St., Bayamon, P. R. 00619
Gerald Kempthorne, M.D.
P.O. Box 4, Spring Green, Wise. 53588
Ronald Lee Krome, M.D.
Receiving Hosp., Detroit, Mich. 48226
Alfred Kronthal, M.D.
Research-Educ. Hosps., Chicago, 111. 60612
Harry V. Langeluttig, Jr., M.D.
Univ. Mo. Med. Ctr., Columbia, Mo. 65202
Philip W. Lankford, M.D.
71 1 Market St., Lewisberg. Pa. 17837
Marc S. Leventhal, M.D.
1271 DeWitt Dr., Akron, Ohio 44313
John P. Light, M.D.
Univ. Hosp., Baltimore, Md. 21201
David E. Litrenta, M.D.
36 N. Main St., York, Pa. 17315
Robert E. Ludike, M.D.
USA Med. Ser. Carib., Det. 1, Ft. Clayton,
Canal Zone 00101
Jerome J. Mahoney, M.D.
USAF Hosp., Tachikawa, APO 323, San
Francisco, Calif. 96423
John R. Marsh, M.D.
Rt. 4, Box 109, Westminster, Md. 21 157
James F. McCarter. M.D.
So. Balto. Hosp.. Baltimore. Md. 21230
Thomas J. McGeoy, Jr., M.D.
Naval Hosp., Jamaica, N.Y. 1 1425
Roger L. Mehl, M.D.
Presby. St. Lukes, 1753 W. Congress Pkwy.,
Chicago, III. 60612
Gerald A. Miller, M.D.
Balto. E. E. T. Hosp., Baltimore, Md. 21217
Charles L. Morreels. Jr.. M.D.
224 Blenheim Rd., Baltimore, Md. 21212
Robert J. Myerburg, M.D.
Charity Hosp., 1532 Tulane Ave., New
Orleans. La. 70140
Michael A. Oldstone, M.D.
Univ. Hosp., Baltimore, Md. 21201
Rodney L. Ortel, M.D.
Balto. E. E. & T. Hosp., Baltimore, Md.
21217
Walter Filmore Oster, M.D.
USPHS Hosp., Bahimore, Md. 21218
Lewis A. Ottenritter, M.D.
9046 Piney Br. Rd., Silver Spring, Md.
20903
Douglas R. Packard, M.D.
P.O. Box 22, Clinton, N. C. 28328
Lawrence J. Pazourek, M.D.
4202 Sheldon Ave., Baltimore, Md. 21206
Clifton C. Presser, M.D.
Hosp. Women of Md., Lafayette Ave. &
John St.. Baltimore, Md. 21217
Kenneth E. Rasmussen, M.D.
c/o American Mission, Box 1111, Addis
Ababa, Ethiopia 00100
Paul A. Reeder, Jr., M.D.
Beckley Appalachian Reg. Hosp., Beckley,
W. Va. 25801
John A. Reeves, M.D.
722 Scott St., Covington, Ky. 4101 1
Earl F. Riter, Jr., M.D.
Hosp. Women of Md., Baltimore, Md. 21217
David Rosen, M.D.
259 Howell Ave., Cincinnati, Ohio 45220
Capt. Richard M. Snarles, USAF MC
86th Tactical Hosp., APO N. Y., N. Y.
09012
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Richard F. Schillaci, M.D.
93 Prentice Rd., Levittown, L. I., N. Y.
11756
Marvin M. Small, M.D.
USA Hosp., USMA, West Point, N. Y.
10996
Thomas M. Sonn, M.D.
Georgetown Univ. Hosp., Washington, D. C.
20007
Wayne B. Tate, M.D.
108 Central Ave., N.W., Glen Burnie, Md.
21061
Larry G. Tilley, M.D.
4625 Arabia Ave., Baltimore, Md. 21214
George E. Urban, Jr., M.D.
Univ. Hosp., Baltimore, Md. 21201
Nina C. Vann, M.D.
550 N. Broadway, Baltimore, Md. 21205
Dennis Vitale, M.D.
USPHS Hosp., Seattle, Wash. 981 14
Brantley P. Vitek, M.D.
Georgetown Univ. Hosp., Washington, D. C.
20007
Zack J. Waters, Jr., M.D.
Spartanburg Genl., Spartanburg, S. C.
29303
Andrew W. Wendling, M.D.
Manhattan E. E. T. Hosp., N. Y., N. Y.
10021
Leiand D. Whitelock, M.D.
7905 Montwood Rd, Baltimore, Md. 21207
John L. Winnacker, M.D.
Vet. Adm. Hosp., Washington, D. C. 20007
Howard M. Wisotzkey, M.D.
Dept. Neurol., Univ. Hosp., Baltimore, Md.
21201
Arthur Wolpert, M.D.
Central Islip Hosp., Central Islip, N. Y.
11722
Anthony J. Young, M.D.
410 Westshire Dr., Baltimore, Md. 21228
Roster of Senior Alumni, 1966-67
At the annual Medical Alumni Associa-
tion banquet in 1964, the president of the
Alumni Association presented to the 50
year graduates of the three schools, their
50-year diplomas. This was the last for
the alumni of the Baltimore Medical Col-
lege, the last class being graduated in June
1914. In 1965 a similar event marked
the last 50 year class for the College for
Physicians and Surgeons. The alumni of
the three schools will then become a single
body.
It is proposed that so long as they shall
live, the individual alumni of the Balti-
more Medical College and the College for
Physicians and Surgeons shall be listed in
the Bulletin of the School of Medicine
each year, so that the identity of these
physicians can properly be maintained.
In addition, the Medical Alumni Asso-
ciation proposes to list all known gradu-
ates of the School of Medicine of the Uni-
versity of Maryland including this group
with the B. M. C.-P. & S group under the
heading "Senior Alumni." Each year the
Bulletin will publish this directory as a
reminder that a large group of active and
distinguished alumni are still in the prac-
tice of medicine a half century or more
after graduation.
The School and the Alumni Association
do not propose to forget these honored
members subsequent to their receiving
the 50-year diploma. Instead, the younger
men might well refer to this senior group
for advice (there are over 400 living alumni
in practice more than 50 years) and counsel.
William Clay Abel, M.D.
2314 Frace Ave
Orlando, Fla.
SENIOR ALUMNI
'01, BMC
A. W. Adkins. M.D., 12, P&S
361 HillsboroSt.
Lexington, Ky. 40505
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
Andrew A. Anderson, M.D., 12. P&S
1 101 DeseretBIdg.
Salt Lake City. Utah
James Leland Anderson. M.D., '08, UofM
213 Butler Ave. or 68 B Vardry St. Med. Ct.
Greenville, S. C. 29607
Charles W. Armstrong. M.D., "14. UofM
629 Mitchell Ave., Salisbury, N. C. 28144
Walter Cathcart Arthur, M.D.. '91,
UofM
2225 Fifteenth St.
Cuyahoga Falls. Ohio 44223
Oscar T. Barber. M.D., 'OS. P&S
Health Oflicer
53 Temple St.
Fredonia. N. Y.
Yates M. Barber. M.D., "14, UofM
275-3
Warsaw, Va. 22572
Carl J. Baumgartner. M.D.. 11. P&S
4841 River Point Rd.
Jacksonville, Fla. 32207
Philip Bean, M.D., '13, UofM
Great Mills, Md. 20634
Grover Cleveland Be.\rd, M.D., '12.
UofM
2709 Locknor Dr.
Raleigh, N. C. 27608
Elmer Jos. Beaulieu, M.D., "07, BMC
215 South Ave.
Whitman. Mass. 02382
Lt. Col. C. L. Beaven. M.D., '08, BMC
1417 Burtonwood Dr.
Alexandria, Va. 22307
William F. Beckner, M.D., "11, BMC
713 West Virginia Bldg.
Huntington, W. Va.
Frederick V. Butler, M.D., "06. UofM
1014 Francis Ave.
Baltimore, Md. 21227
Harry J. Bennett. M.D., "06, BMC
121 N.Julian St.
Ehensburg, Pa.
Clarence Irving Benson, M.D., "09, UofM
Box 123
Port Deposit, Md. 21904
Rafael Bernabe. M.D., "13, P&S
61 Savador Brau St.
San Juan. P. R.
Harry Mei chior Biffar, M.D., "12, P&S
144-31 14th Ave.
Flushing. N. Y.
CoL. Harry Aloysius Bishop, M.D., '12,
UofM
3718 Manor Road
Chevy Chase, Md. 20015
William P. Black, M.D., '14, P&S
1 1 1 Capitol St.
Charleston, W. Va. 25300
LowRiE W. Bl.^ke, M.D., '14, UofM
5609 7th Ave. Dr., W.
Bradenton, Fla. 33505
Walter D. Blankenship, M.D., '10, P&S
31 Sunset Place
Lancaster, Pa.
James G. Blower. M.D., '05, P&S
308 Rose Blvd.
Akron. Ohio 44302
O. H. Bobitt, M.D., '14, P&S
863 24th Ave., N.
St. Petersburg, Fla. 33713
Ray Maxwell Bobbitt, M.D., '13, P&S
1139 4th Ave.
Huntington, W. Va.
Alvah p. Bohannan, M.D., '05, UofM
Virgilina, Va. 24598
Lawrence F. Boland, M.D., '11, BMC
P. O. Box 339
Frankfort. Ky. 40601
William P. Bonar, M.D., '06, P&S
1006 Tomlinson Ave.
Moundsville, W. Va. 26041
Robert A. Bonner, Sr., M.D., '12, UofM
51 West Main St.
Waterbury, Conn. 06702
Charles F. Bove, M.D., '13, BMC
70 E. Main St.
Patchogue, N. Y. 11772
Lee Bransford, M.D., '10, BMC
1282MayfairRd.
Jacksonville, Fla. 32207
Harrison L. Brehmer, M.D., '10, P&S
106 Girard Blvd., S.E.
Albuquerque, N. Mexico 87106
Januarv, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
James C. Brogden, M.D., '14, UofM
210UticaSq. Med. Ctr.
1980 Utica Sq.
Tulsa, Okla. 74114
Frank J. Broschart, M.D., '11, BMC
8 Russell Ave.
Gaithersburg, Md. 20760
Morton Brotman, M.D., '14, UofM
2 1 2 South Orange Ave. , Apt. # 1
South Orange, New Jersey
Archie Eugene Brown, M.D., '11, UofM
918 Poinsett Highway
Greenville, S. C. 29609
Joseph Edward Brumback, M.D., '09,
BMC
Medical Arts Bldg.
Baltimore, Md. 21201
Jesus Maria Buck, M.D., '13, UofM
1004 E. 36th St.
Baltimore, Md. 21218
Sidney Eli Buchanan, M.D., '12, UofM
390 S. Union St.
Concord, N. C.
Louis Arthur Buie, M.D., '15, UofM
200 First St., S.W.
Rochester, Minn. 55901
Frank Burden, M.D., '05, UofM
:^ 3 Bagshaw Ave.
Brighton, South Australia
J. J. Burne, M.D., '10, P&S
101 N. Grove St.
East Orange, N. J. 07017
Ira Burns, M.D., '05, UofM
2800 N. Atlantic, Apt. 605
Daytona Beach, Fla. 32018
Julian G. Busby, M.D., "04, UofM
901 W. Henderson St.
Salisbury, N. C. 28144
Lawt^ence a. Cahill, M.D., '1 1, BMC
361 Lafayette St.
Newark, N. J.
Charles A. Cahn, M.D., '15, UofM
2145W. BahimoreSt.
Baltimore, Md. 21223
Fred Glover Campbell, M.D., 11, BMC
Warren, Maine 04864
Jesse W. Campbell, M.D., '09, BMC
923 Philadelphia St.
Indiana, Pa.
Ovid Sylvester Campbell, M.D., '10, P&S
Grafton, W. Va.
Harry Arthur Cantwell, M.D., '06,
UofM
Cecil Ave.
North East, Md. 21901
Manuel G. Carrera, M.D., '14, P&S
101 N.Union St.
Fajardo, P. R. 00648
Col. Henry P. Carter, M.C, '03, UofM
3445B S. Stafford St.
Arlington, Va.
Arthur Casilli, M.D., '14, UofM
618 Newark Ave.
Elizabeth, N. J. 07203
Giuseppe Caturani, M.D., '10, UofM
348 E. 11 6th St.
New York, N. Y.
Louis Chargin, M.D., '02, BMC
1 W. 85th St.
New York City
Charles Peter Clautice, M.D., '12, UofM
3013 St. Paul St.
Baltimore, Md. 21202
Hubert Clayter, M.D., '86, UofM
Hopkins, S. C.
Morris D. Cohen, M.D., '04, P&S
1534 East Speedway
Tucson, Arizona 85719
Ralph Cohen, M.D., '15, UofM
23 1 1 University Blvd. West
Silver Spring, Md. 20902
Joseph Coleman, M.D., '04, UofM
455 West 23rd St.
New York 11,N. Y.
Clarence E. Collins, M.D., '02, UofM
"The Hygeia." Hall Highway
Crisfield.Md. 21817
Wm. Stanislaus Conway, M.D., '10, UofM
3210E. Perkins Ave.
Sandusky, Ohio
Everett L. Cook, M.D., '14, UofM
nOSlade Ave., Apt. 306
Baltimore. Md. 21208
Vo}. 51. No. 1
ALUMNI ASSOCIATION SECTION
C. Melvin Coon, M.D.. '03, UofM
Milan, Pa.
Everett Roy Cooper, M.D.. "12. P&S
Troy, W. Va.
Earle Somerville Coster, M.D., '06,
UofM
Solomons, Md. 20688
George C. Coulbourne, M.D.. "10, UofM
Marion, Md. 21838
Franklin Clyde Craven, M.D. "13, UofM
525 Sunset Ave.
Ashboro, N. C.
Henry L. Criss, M.D., UofM
218 Adams St.
Fairmont, W. Va.
Denis J. Cronin, M.D.. "10, UofM
1007 4th Ave.
Huntington. W. Va.
Gilbert L. Dailey, M.D., "14, UofM
618 3rd St.
Harrisburg. Pa. 17101
M. Tolbert Dalton, '06, UofM
6811 50th Ave., N.E.
Seattle 15, Wash.
Ch.\rles W. Daly. M.D., '10, P&S
139 Warrenton Ave.
Hartford, Conn. 06105
George Davis. M.D., "08, UofM
28 South Church St.
Waynesboro, Pa.
Theodore McCann Davis, M.D., '14,
UofM
108 Vannoy St.
Greenville, S. C.
Joseph L. DeCormis, M.D., UofM
Accomac, Va.
Harry Deibel, M.D., '12, UofM
1226 Hanover St.
Baltimore, Md. 21230
Walter L. Denny, Jr., M.D., '14, UofM
3908 N. Charles St.
Baltimore, Md. 21218
James DePasquale, M.D., '08, BMC
530 E. 234th St.
New York 70, N. Y.
James E. Diehl, M.D.,
1627 Hanover Ave.
Richmond 20, Va.
II, UofM
Louis Diener, M.D., '15, UofM
25 1 1 Eutaw Place
Baltimore, Md. 21217
J. D. DiNSMORE, M.D., '09, UofM
Port Clyde
Nova Scotia, Canada
Edward P. Disbrow. M.D., '08, UofM
15 Irving St., Apt. 9
Worcester, Mass.
James Sylvester Dixon, M.D., UofM
33 Parsonage St.
Pittston, Pa.
Harry C. Donahoo, M.D., UofM
2428 Edgmont Ave.
Chester, Pa.
James Corbin Doughty, M.D., UofM
Onancock, Va.
Col. Chauncey E. Dovell, M.D., '14,
UofM
62 S. Bo.xwood St.
Hampton, Va. 23369
Joseph Lee Dowling, M.D., '15, UofM
207 Waterman St.
Providence, R. I. 02906
John H. Doyle, M.D., '02, UofM
North Dighton, Mass.
Manuel Dueno Y Dueno, M.D., ' 05,
UofM
571 West 139th St.
NewYork, N. Y. 10031
James Fender Easton, M.D., '13, UofM
45 Rosemary Lane
Romney, W. Va.
Vivian P. Edwards, M.D., UofM
27 Hillside Ave.
Edwardsville, Kingston, Pa.
Michael Joseph Egan, Jr., M.D., UofM
210 East Liberty St.
Savannah, Ga.
Samuel E. Enfield, M.D., '13, P&S
1 1 6 South Liberty St.
Cumberland, Md. 21502
Richard Esslinger, M.D., '14, UofM
3720 Glenmore Ave.
Baltimore, Md. 21206
John Evans, M.D., '03, BMC
321 Regester Ave.
Baltimore, Md. 21212
January, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Remo Fabbi, M.D., '09, BMC
1731 Markley St.
Norristown, Pa.
Dawson L. Farber, M.D., '13, BMC
305 Woodlawn Rd.
Baltimore, Md. 21210
Lee K. Fargo, M.D., '15, P&S
8155 Loch Raven Blvd.
Baltimore, Md. 21204
George L. Faucett, M.D., '03, P&S
908 Walnut St.
Gadsden, Ala. 35901
Isaiah Fearing, M.D., UofM
Elizabeth City, N. C.
Lloyd H. Feick, M.D., UofM
807 N. 10th St.
Reading, Pa.
Antonio Fernos-Isern, M.D., '15, P&S
1710 New House Office Bldg.
San Juan, P. R.
Charles Wm. Finnerty, M.D., '13, UofM
440 Broadway
Somerville, Mass.
Frank P. Firey. M.D., UofM
2224N. E. 46thSt.
Portland 13, Ore.
Edward E. Fitzpatrick, M.D., '15, P&S
317 36th Ave., N.E.
St. Petersburg, Fla. 33704
Paul N. Fleming, M.D., '13, UofM
8627 Fenton St.
Silver Spring, Md. 20910
Edgar T. Flint, M.D., UofM
Raritan, N. J.
Ernest F. Flora, M.D., '13, UofM
Boones Mill, Va.
H. M. Foster. M.D., '10, UofM
Ilchester Rd.
Ellicott City. Md. 21043
Ernest Wm. Frey, M.D., '12, UofM
1928 Pennsylvania Ave.
Baltimore, Md. 21217
Edgar B. Friedenwald, M.D., '03, P&S
1701 Eutaw PL, Apt. 1-B
Baltimore, Md. 21217
James C. Frye, M.D.,'11,
407 First St.
Williamsburg, Pa.
BMC
William L. Funkhouser, M.D., '04, UofM
47 Peachtree Park Rd.
Atlanta, Ga. 30309
Charles W. Gardner, M.D., '01, UofM
49 Toilsome Hill Rd.
Bridgeport, Conn. 06604
George W. Gault, M.D.. "10, UofM
112 Walnut St.
Harrisburg, Pa.
W. Frank Gemmill. M.D., '13, UofM
121 W. Springettsbury Ave.
York, Pa.
Dawson Orme George, M.D., '12, UofM
Denton, Md. 21629
Henry J. Giamarino, M.D., "06, BMC
291 Whitney Ave.
New Haven, Conn. 0651 1
William T. Gocke, M.D., UofM
207 W. Pike St.
Clarksburg, W. Va.
Leo Goldbach, M.D., '05, UofM
212 Stratford Rd.
Baltimore, Md. 21218
Albert Goldey, M.D., "12, UofM
210W. 101st St.
New York 25, N. Y.
Harris Goldman, M.D., '10, P&S
3507 Garrison Blvd.
Baltimore, Md. 21215
Harry Goldsmith, M.D., '13, UofM
3109Marnat Rd.
Baltimore, Md. 21208
Luis Felipe Gonzalez, M.D., '15, P&S
BoxB
Rio Grande, P. R.
Attie Thompson Gordon, M.D., '14, P&S
Spencer, W. Va. 25276
Gust AVE A. Gorisse, M.D., "II, BMC
7329 Kings Run Rd.
Dayton, Ohio 45459
Arthur Richard Gould. M.D., '03, BMC
70 El Portal
Greenbrae, Calif. 94901
Don U. Gould, M.D., "05, BMC
N. Main St.
Sherburne, N. Y. 13460
xl
Vol. 51, No. 1
JLUMXr .ISSOCf.-lTIOM SECTION
Archibai d \V. Graham. M.D.. UofM
Box 563
Chisholm. Minn.
Garland Grazier, M.D., UofM
Hollsopple, Pa.
Charles Jacob Greenstein, M.D., '12,
BMC
300 Main St.
New Britain, Conn. 06501
George F. Grisinger. M.D., '10, P&S
2861 Piedmont Rd.
Charleston. W. Va.
Julius E. Gross, M.D., "07, UofM
9576 Collins Ave.
Surfside, Fla. 33154
Frank W. H.acktel, M.D., UofM
122 W. Lafayette Ave.
Baltimore, Md. 21217
Glenn G. Haight, M.D., UofM
Audubon, New Jersey
Edward St. C. Hamilton, M.D., '11, UofM
Oak Hill, W. Va.
Nathan S. Hanellin, M.D., '11, UofM
152 I82ndSt.
Brooklyn, N. Y. 11209
Cecil Hassell, M.D., '14, UofM
507 E. Carolina Ave.
Crewe, Va.
Cecil Starke Hassell, M.D., '14, UofM
2939 S.W. 5th St.
Miami, Fla. 33135
Leonard Hays, M.D., '13, UofM
5201 Baltimore Ave.
Hyattsville,Md. 20781
Howard Carrington Heilman, M.D.,
UofM
Elderton, Pa.
IsiDOR Heller, M.D., '13, UofM
49 Brandon Rd.
Upper Darby, Pa.
Frederick H. Herrman, M.D., '07, UofM
1710 E. 33rd St.
Bahimore, Md. 21218
Arthur Wm. Higgins, M.D., "07, UofM
McLain Bldg.
Wheeling, W. Va.
Robert B. Hill, M.D., '15, UofM
Southern Pines, N. C.
Simon Wickline Hill, M.D., UofM
Regent, N. Dakota
John J. H. Hilton, M.D., UofM
336 Haverhill St.
Lawrence, Mass.
IsADORE Hirschman, M.D., 'II, UofM
618 11th Ave.
Huntington, W. Va.
Henry Hiram Hodgin, M.D., UofM
Red Springs, N. C.
Maxey Gregg Hoffman, M.D., UofM
Bunker Hill, W. Va.
John F. Hogan, M.D., 'II, UofM
Bo.\ 113
GibsonIsland,Md. 21056
Howard Steele Holloway, M.D., '03,
UofM
Perryman, Md. 21 130
Francis Hutchinson, M.D., '1 1, UofM
485 E. Howard St.
Pasadena, Calif. 91104
Manuel R. Janer, M.D., '12, UofM
697 West End Ave.
New York 25, N. Y.
Leon Peter Jankiewicz, M.D., UofM
914 State St.
Utica, N. Y.
Harry E. Jenkins, M.D., '05, UofM
Farmville, Va.
Jesse J. Jenkins, M.D., '14, P&S
Farmington, W. Va. 26571
William H. Jenkins, M.D., '15, UofM
2024 R St., N.W.
Washington 9, D. C.
Frank Leslie Jennings, M.D., '11, P&S
Medical Arts Bldg.
Baltimore, Md. 21201
Charles Sterling Jernigan, M.D., '97,
BMC
350 Boulevard S. E.
Atlanta, Ga.
William R. Johnson, M.D., '15, UofM
403 Medical Arts Bldg.
Baltimore, Md. 21201
Kenneth B. Jones, M.D., '11, UofM
Church Creek, Md. 21622
January, 1966
xli
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Solomon Chas. Katzoff, M.D., '40, UofM
Keystone Realty Co.
907 Whitelock St., 1st Floor Apt.
Baltimore, Md. 21217
Charles Hutchison Keesor, M.D., '11,
UofM
2302 Chapline St.
Wheeling, W. Va.
Col. Lloyd A. Kefauver, M.D., '06, BMC
665 S. Skinner Blvd.
St. Louis, Mo. 63105
Charles Keller, M.D., '98, UofM
222 W. Monument St.
Baltimore. Md. 21201
Roy R. Kerkow, M.D., '15, Uof M
505 Yakima St.
Wenatchee, Wash.
George S. M. Kieffer, M.D., '03, UofM
1010 Leeds Ave.
Baltimore, Md. 21229
George Breon Kirk, M.D., UofM
Kylertown, Pa.
George Alfred Kohler, Jr., M.D., '12,
P&S
Smithburg.Md. 21783
Lawrence B. Kolb. M.D., '08, UofM
6645-32nd St., N.W.
Washington, D. C. 20015
Charles Byron Korns, M.D., UofM
Sipesville, Pa.
Harry Stanley Kuhlman, M.D., '14, P&S
Sharptown, Md. 21861
Julius Joseph Kvatsak, M.D., UofM
3521 California Ave.
Pittsburgh, Pa.
Anthony W. Lamy, M.D., '08, P&S
585 Newark Ave.
Elizabeth, N. J. 07208
Alston Howard Lancaster, M.D., '03,
UofM
997 Main St.
Worcester 3, Mass.
Wm. E. Van Landingham, M.D., '05, BMC
328 Dyer Ave.
West Palm Beach, Fla. 33405
Hubert Leonard Langer, M.D. '14, P&S
212 Beach 69th St.
Far Rockaway, N. Y. 1 1692
Frank V. Langfitt, M.D., '07, BMC
227 Carr Ave.
Clarksburg, W. Va.
Philimon S. Lansdale, M.D., "02, UofM
100 E. Church St.
Frederick, Md. 21701
Enrique Lasisse y Rivera, M.D., UofM
Sabana Grande, P. R.
Augustin R. Laugier, M.D., '14, P&S
Bo.x 298
San Juan, P. R. 00902
Charles R. Law, Jr., M.D., '11, UofM
Berlin, Md. 21811
Oram R. La wry. Sr., M.D., '11, P&S
23 Oak St.
Rockland, Maine 04841
J. Walter Layman, M.D., '10, BMC
5 Public Square
Hagerstown, Md. 21740
Ernest Chas. Lehnert, M.D., '02, UofM
3003 N. Charles St.
Baltimore, Md. 21218
Simon Geilech Lenzner, M.D., '12, UofM
187 Waterman St.
Providence 6, R. L
Morris B. Levin, M.D., '14, UofM
218 University Pkwy.
Baltimore, Md. 21218
Addison LeRoy Lewis, M.D., UofM
Havre de Grace, Md.
Nolan D. C. Lewis. M.D., '14, UofM
Rt.#5
Frederick. Md. 21701
Louis Herbert Limauro, M.D., '06, UofM
374 Charles River Rd.
Watertown, Mass.
R. Basil Linger, M.D., '15, P&S
321 W. Main St.
Clarksburg, W. Va.
Joseph Lipskey, M.D., '14, P&S
Odenton ( A. A. Co. ) , Md. 2 1 1 1 3
Bernard Livingston, M.D., '08, BMC
535 S. Shore Dr.
Miami Beach, Fla. 33141
Thomas P. Lloyd. M.D., '96, BMC
1030 Highland Ave.
Shreveport, La. 71101
xlii
Vol. 51, No. 1
ALUMNI ASSOCIATION SECTION
Arthur M. Loope. M.D., "98. BMC
217 Sherbourne Rd.
Syracuse. N. Y. 13224
John Robert Lowerv. M.D.. UofM
Salisbury', N. C.
John F. Lutz, M.D., "14, UofM
72 Southgate Ave.
Annapolis, Md.
John Vincent McAninch, M.D.. '14. P&S
308 W. Lincoln Ave.
McDonald, Pa. 15057
Dr. Frederick L. McDonald, M.D., '13,
UofM
44 Northdown Rd.
Alexandria, Va.
Albert D. McFadden. M.D., '14, UofM
4313 Marble Hall Rd.
Baltimore, Md. 21218
William P. McGuire. M.D., UofM
Wylliesburg, Va.
Henry Hupp McIntire, M.D., UofM
406 Green St.
Connellsville, Pa.
William R. McKenzie, M.D., '15, UofM
117TaplowRd.
Baltimore, Md. 21212
RoscoE Drake McMillan, M.D., UofM
Red Springs, N. C.
C. W. McPherson, M.D., '10, UofM
305 W. Front St.
Burlington, N. C.
Clyde C. Mack, M.D., '04, UofM
872 24h St.
Winter Haven, Fla. 33880
Is.^ac M. Macks, M.D., '11, UofM
3506 Liberty Heights Ave
Baltimore, Md. 21215
A. M. Magarian, M.D., '05, BMC
330 W. Ocean Blvd.
Long Beach, Calif. 90802
Charles L. Magruder, M.D., '14, UofM
lOlON.Bundy Drive
Los Angeles, Calif. 90049
John E. Maker, M.D., '14, P&S
96 Third Aye.
Long Branch, N. J. 07740
Vernon L. Mahoney, M.D., '15. P&S
2725 E. Exeter
Tucson, Ariz. 85716
Ernesto. Marr, M.D., '13, UofM
516 Cathedral St.
Baltimore, Md. 21201
WiiMAM Reginald Marshall, M.D., UofM
22 Broad St.
Boston, Mass.
William E. Martin, M.D., '09, UofM
Randallstown, Md. 21133
William T. Martin, M.D., UofM
605 McDaniels Ave.
Greenville, S. C.
Erwin Mayer, M.D., '14, P&S
TTie Esplanade Apts.
Baltimore, Md. 21217
Frederick W. A. Mayer, M.D., '03, UofM
1830 James Ave.
St. Paul 5, Minn.
John L. Meeker, M.D., '03, UofM
6 DeBarry Place
Summit, N. J.
M. L Mendeloff, M.D., '12, UofM
Box 92 1
Charleston 23, W. Va.
Harry B. Messmore, M.D., UofM
Addison, Pa.
Challice Haydon Metcalfe, M.D., '14,
UofM
Sudlersville, Md. 21668
Isidor Michel, M.D., '11, UofM
870 5th Ave.
NewYork, N. Y. 10021
Carl F. Miller, M.D., '04, BMC
5554 Delmar
St. Louis, Mo.
Samuel Miller, M.D., '12, BMC
2807 Arthur St.
Hollywood, Fla. 33020
William C. Miller, M.D., UofM
Gaithersburg, Md.
David C. Mock, M.D., '04, P&S
215CajonSt.
Redlands, Calif. 92373
Daniel B. Moffett, M.D., UofM
1 1 50 Connecticut Ave., N.W.
Washington, D. C.
January, 1966
xliii
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Alfred N. Moore, M.D., '03, BMC
16 Pike St.
Oakland, 111. 61943
Emmett a. Moore, M.D., '08, UofM
Box 247
Newark, Ohio
Col. Alfred Mordecai, M.D., '14, UofM
806 S. Hawthorne Rd.
Winston-Salem, N. C.
Charles G. Morgan, M.D., UofM
156 Santa Barbara St.
Corpus Christi, Texas
Samuel J. Morris, M.D., UofM
205 Kingwood St.
Morgantown, W. Va.
Theodore Morrison, M.D., '15, UofM
100 W. Cold Spring Lane, Apt. 704 West
Baltimore, Md. 21210
C. H. Moses, M.D., UofM
919 Linden Ave.
Sharon, Pa.
Charles L. Mowrer, M.D., '13, UofM
159 W.Washington St.
Hagerstown, Md. 2 1 740
Leo p. Musser, M.D., '13, UofM
500 Vine Hill Way
Martinez, Calif. 94553
Charles W. Myers, M.D., "15, UofM
R. D. 18, Box 256
Indianapolis, Ind. 46224
William Edgar Myles, M.D., UofM
White Sulphur Springs, W. Va.
Victor C. Nah, M.D., '13, UofM
301 North Van Buren St.
Wilmington, Del. 19805
Walter Irving Neller, M.D., UofM
121 Wickhan Ave.
Middletown, N. Y.
Benjamin Newhouse, M.D., '12, UofM
4213 16thSt.,N.W.
Washington, D. C. 20011
Walter S. Niblett, M.D., '11, UofM
1141 Gypsy Lane East
Bahimore, Md. 21204
Charles Francis Nicol, M.D., '13, P&S
63 Prospect Pk. W.
Brooklyn 15, N. Y.
Juan J. Nogueras, M.D., '15, P&S
468 Caribe St.
Box 1214
San Juan, P. R.
Lester D. Norris, M.D.. '08, UofM
Fairmont General Hospital
Fairmont, W.Va. 26551
Arthur M. O'Connor, M.D., '09, UofM
Lee, Massachusetts
John Charles O'Neil, M.D., '14, UofM
P. O. Box 158
Savannah, Ga. 31402
Walter A. Ostendorf, M.D., '13, UofM
420 West Elsmere
San Antonio 12, Texas
John Ostro, M.D., '11, UofM
5234 Dorchester Ave.
Chicago, III. 60615
Samuel Watson Page, M.D., UofM
Greenwood, S. C.
Julius G. Paider, M.D., '00, BMC
405 E. 72nd St.
New York, N.Y. 10021
Harold H. Palmer, M.D., UofM
Plymouth, N. H.
William N. Palmer, M.D., '05, P&S
P. O. Box 558
Easton, Md. 21601
Paul Jones Parker, M.D., UofM
Hampton, Va.
James B. Parramore, M.D., '09, UofM
523 Whitehead St.
Key West, Fla. 33040
Benjamin Parvey, M.D., UofM
636 Beacon St.
Boston. Mass.
T. E. Patteson, M.D., '09, UofM
Dillwyn, Virginia
Ernest M. Perry, M.D.. UofM
125 Sunset Ave.
Rocky Mount, N. C.
Charles J. Pflueger, M.D., '05, BMC
460 S. Ardmore St.
Los Angeles, Calif. 90005
George Henry Pflueger, M.D., '06, BMC
40 Dole Ave.
Crystal Lake, III. 60014
xliv
Vol. 51. No. 1
ALUMNI ASSOCIATION SECTION
Lawrence D. Phillips, M.D., '19, UofM
3301 Newport Gap Pike
Wilmington, Dei. 19808
Wn I lAM Garfield Phh lips, M.D., UofM
Skiatook. Okla.
George Piness, M.D., "13, UofM
240 S. LaCienga Blvd.
Beverly Hills, Calif. 90211
Linn F. Playse, M.D., "06, UofM
4340 Juanita Way. South
St. Petersburg 5, Fla.
Walter W. Point, M.D., "13, UofM
Bo.\ 2567
Charleston 29, W. Va.
John T. H. Powers, M.D., "10, UofM
55 West St.
Leominster, Mass.
Ivan Emerson Pratt, M.D., UofM
Millerton, Pa,
Wilmer Marshall Priest, M.D., '09.
UofM
55 West 184th St.
New York 28, N. Y.
Manuel E. Pujadaz-Diaz, M.D., '14, P&S
1611 Colon Ave.
Sancturce, P. R. 00911
Clayton T. Ralls, M.D., "04, P&S
Box 608
Winfield, Kansas 67156
Watson S, Rankin, M.D., "01, UofM
Methodist Home
Charlotte 5, N. C.
Moses Raskin, M.D., '15, UofM
622 1 Greenspring Ave.
Baltimore, Md. 21209
Edwin R. Raymaley, M.D., '04, UofM
1034 South Ave.
Pittsburgh 21, Pa.
Harry Cornelius Raysor, M.D., '13, UofM
St. Matthews, S. C.
Robert P. Reagan, M.D., '08, BMC
345 Goundry St.
North Tonawanda, N. Y.
Ralph G. Reed, M.D., '08, BMC
330 Elmore St.
Central Islip, N. Y.
CoL. Walter I. Richards, M.D., '14, UofM
Box 11, Route 4
Charlottesville, Va.
Capt. Willard J. RiDDicK, M.D., '05, UofM
7426 Dominican St.
New Orleans, La. 70118
Harry Young Righton, M.D.. '07, UofM
401 E. 45th St.
Savannah, Ga. 3 1 405
John Wm. Robertson, M.D., '09, UofM
Onancock, Va.
Joseph R. Robertson, M.D., '10, UofM
1700 Johns Road, Ext.
Augusta, Ga. 30904
Jacob Roemer, M.D., '06, BMC
465 S. Westgate Ave.
Los Angeles, Calif. 90049
Joseph U. Rohr, M.D,, '14, P&S
3705 Bohan St., N.E.
Roanoke, Va. 24012
George Rosenbaum, M.D., '05, BMC
7608 Coventry Ave.
Philadelphia, Pa. 19126
George Rosenbaum, M.D., '05, UofM
1030 Rock Creek Drive
Wyncote, Pa.
Jacob L. Rosenstein, M.D., '05, P&S
568 Bergen Ave.
Jersey City, N. J.
Willum T. Ruark, M,D., '15, UofM
Pinecrest Sanatorium
Beckley, W. Va. 25801
Louis Rubin, M.D., '10, UofM
10510 Euclid Ave.
Cleveland 6, Ohio
John G. Runkel, M.D., '10, UofM
715 Charing Cross Rd.
Baltimore, Md. 21229
Raymond Harrison Ryder, M.D., '13,
UofM
48 Central Ave.
Waterbury, Conn. 06702
Lucius C. Saunders, M.D., '15, UofM
20 S. Dudley St.
Memphis, Tenn. 38303
Harry Schnuck, M.D., '15, UofM
1203SanDiegiatoSt.
Encinitas, Calif. 92024
January, 1966
xlv
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Fred C. Schumacher, M.D., '05, P&S
Chichester Rd.
Phoenicia, N. Y. 12464
Leonard O. Schwartz, M.D., '12, P&S
3421 Pennsylvania Ave.
Weirton, W. Va.
William H. Scruggs, M.D., '13, UofM
Andrews, N. C.
George H. Seaks, M.D., '04, UofM
New Oxford, Pa.
Elias C. Segarra, M.D., '13, P&S
1803 Ponce de Leon Ave.
Santurce, P. R. 00929
Herman Seidel, M.D., '10, P&S
2404 Eutaw Place
Baltimore, Md. 21217
Roger K. Sell, M.D., '13, BMC
Torrington, Wyoming 82240
Charles I. Shaffer, M.D., '07, BMC
725 East Main St.
Somerset, Pa.
Maurice E. Shamer, M.D., '10, UofM
3300 West North Ave.
Baltimore, Md. 21216
Albert C. Shannon, M.D., '12, UofM
R. D. 1, Box 83
Mayport, Pa.
J. D. Sharp, M.D., '12, UofM
Box 849, Shifting Shadows
Twenty-Nine Palms, Calif. 92277
Arthur A. Shawkey, M.D., '00, P&S
207 Beuregard St.
Charleston 1 , W. Va.
Richard O. Shea, M.D., '14, P&S
25 Sanford Place
Bridgeport, Conn. 06604
Frank E. Shipley, M.D., '15, UofM
Savage, Md.
Ivy G. Shirkey, M.D., '14, P&S
Albemarle Apts.
1830 17thSt.,N.W.
Washington, D. C. 20009
David Silberman, M.D., '12, UofM
:^508 Temple Garden Apts.
2601 Madison Ave.
Baltimore, Md. 21217
Albert George Singewald, M.D., '02,
UofM
1613E. North Ave.
Baltimore, Md. 21213
John Andrew Skladowsky, M.D., '12,
UofM
Box 181, Route # 1
Severna Park, Md. 21 146
Henry Oscar Sloane, M.D., '08, BMC
23 S. Hillside Ave.
Ventnor, N. J. 08406
Hamilton J. Slusher, M.D., '13, UofM
Rt. 4, Box 118
Fredericksburg, Va. 22401
Arthur Charles Smith, M.D., '10, P&S
90 Deer Hill Ave.
Danbury, Conn. 06810
ZiBA L. Smith, M.D., '06, P&S
West Nanticoke, Pa.
Earl H. Snavely, M.D., '05, BMC
4800 San Amaro
Coral Gables, Fla. 33146
Frederick Snyder, M.D., '08, UofM
44 Clinton Ave.,
Kingston, N. Y.
Dallas C. Speas, M.D., '11, UofM
2598 Reynolds Rd.
Winston-Salem, N. C.
Hugh R. Spencer, M.D., '10, UofM
3900 N. Charles St.
Baltimore, Md. 21218
Edward Wharton Sprague, M.D., '03, P&S
86 Washington St.
Newark, N. J.
Clarke J. Stallworth, M.D., '12, UofM
Thomaston, Ala. 36783
Byron Wm. Steele, M.D., '14, P&S
Box 248
Mullens, W. Va. 24863
Fred E. Steele, Jr., M.D., '07, UofM
Florence, Mass.
Paul Beadle Steele, M.D., '15, P&S
7059 Jenkins Arcade
Pittsburgh, Pa. 15222
Jacob J. Steinfelder, M.D., '08, BMC
924 West End Ave.
New York City, N. Y.
xlvi
Vol. 51, No. 1
ALUMXI ASSOCIATION SECTION
Thomas VVm. Stevenson, M.D., '08, P&S
4421 Montaire Ave.
Long Beach, Calif. 90808
George L. Stickney, M.D., '10, Uol'M
1 04 West University Pkwy.
Baltimore, Md. 21210
Washington Waters Stonestreet, M.D.,
•06, UofM
231 Locust Ave.
Fairmont, West Va.
Frank Gregorv Strahan. M.D., "14, UofM
Williamsville, Vt.
George L. Straub, M.D., '11, UofM
41 17 Anderson Rd.
CoralGables.Fla. 33146
Charles Franklin Strosnider, M.D., '09,
UofM
P. O. Box 245
Goldsboro, N. C.
B. F. Tefft, M.D., '05, UofM
185 Washington St.
West Warwick, Rhode Island
Bernard Osc.\r Thomas, Sr., M.D., '06,
UofM
228 N. Market St.
Frederick, Md. 21701
John M. Thorup, M.D., '15, P&S
4927 N. E. 30th Ave.
Portland, Oregon
Homer U. Todd, M.D., "08, UofM
2108 St. Paul St.
Baltimore, Md. 21218
Grafton Dent Townshend, M.D., '11,
UofM
1141 Roscomore Rd.
Los Angeles, Calif. 90024
William J. Trainor, M.D., '03, BMC
326 Virginia Circle
Wilmington, Ohio
Letcher E. Trent, M.D., '10, P&S
209 DeWitt Rd.
Syracuse 3, N. Y.
Richard Trevaskis, Sr., M.D., '11, UofM
220 Baltimore Ave.
Cumberland, Md. 21502
William H. Triplett, M.D., '11, BMC
1038 LakemontRd.
Baltimore, Md. 21228
Karl H. Trippett, M.D.,'11, P&S
Grafton, W. Va.
Ralph C. Purnell, M.D., '10, UofM
Great Neck Farm
Stevensville, Md. 21666
Jesse R. Tuckwiller, M.D., '10, P&S
223 Monroe St.
Fairmont, W. Va.
Alfred Ullman, M.D., '02, P&S
1 702 Eutaw Place
Baltimore, Md. 21217
Wm. Lawrence Van Sant, M.D., '10,
UofM
Hinton, W. Va.
Thurman Elroy Vass, M.D., '14, P&S
Bo.x 1 67
Bluefield,W.Va. 24701
Clyde W. Vick, M.D., '05, P&S
2117 Jefferson St.
Bluefield, W. Va.
Frederick J. Waas, M.D., '05, UofM
1 804 Mayview Rd.
Jacksonville, Fla. 32210
Joseph Judson Waff, M.D., '15, UofM
Box 235
Shenandoah, Va.
Adam. C. Walkup, M.D., '09, UofM
33 Water St.
St. Augustine, Fla. 32084
Wm. Benj. Warthen, M.D., '05, UofM
Davisboro, Ga. 31018
Earl B. Weible, M.D., '10, BMC
Abercrombie, N. Dakota
Meyer A. Weinberg, M.D., '04, UofM
1724 Eutaw Place
Baltimore, Md. 21217
Parker M. Wentz, M.D., '06, P&S
752 Kelly Drive
York, Pa.
Cleveland D. Whelchel, M.D., '13, UofM
1735 Riverside Drive
Gainesville, Ga. 30501
Edwin Vignes Whitaker, M.D., '12, UofM
Box 625
Baton Rouge, La. 70821
Col. Wm. A. Wickline, M.D., '95, P&S
232 Rutherford Drive
Danville, Calif. 94526
January, 1966
xlvii
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Java C. Wilkins, M.D., '11, UofM
Box 446
Haw River, N. C. 27258
David T. Williams, M.D., '14, UofM
21 Hall Ave.
Newark, Ohio
Louis V. Williams, M.D., '11, P&S
Route 7
York, Pa.
Mayes B. Williams, M.D., '12, P&S
2000 Eoff St.
Wheeling, W. Va.
Ernest L. Wilson, M.D., '11, BMC
10509 Stone Ave.
Seattle 33, Wash.
Walter Michael Winters, M.D.,
UofM
288 Broadway
Paterson, N. J.
Francis R. Wise, M.D., '08, P&S
129 E. Market St.
York, Pa. 17401
'10,
Walter D. Wise, M.D., '06, P&S
most. Paul St.
Baltimore, Md. 21202
John I. Wiseman, M.D., '07, P&S
215 Annie St.
Orlando, Fla. 32806
Austin H. Wood, M.D., '14, UofM
Medical Arts Bldg.
Baltimore, Md. 21201
Eugene Bascom Wright, M.D., '09, UofM
340 Buckhannon Ave.
Clarksburg, W.Va. 26301
Silas G. Wright, M.D., '04, UofM
Shawboro, N. C.
Eugene Zeller, M.D., '15, UofM
2739 Eastern Ave.
Baltimore, Md. 21224
Mark V. Ziegler, M.D., '15, UofM
OIney, Md. 20832
W. F. ZiNN, M.D.,'11,P&S
400 Coral Way
Ft. Lauderdale, Fla. 33301
xlviii
Vol. 51, No. 1
BULLETIN School of Medicine
Universift/ of MarijJaiid
VOLUME 51
APRIL 1966
NUMBER 2
TABLE OF CONTENTS
ORIGINAL ARTICLES
A Correlative Study of Chronic Arterial Hypertension and Pregnancy -
Isadore G. Ances, M.D., Arthur Haskins, M.D.
Benign Localized Fibrous Mesothelioma of Pleur
Joseph Milieu, M.D.
Chromosomal Mosaicism in Gonadal Dysgenesis — Report of a Case-
Hans-Dieter Tauberl, M.D., Erica F. Moszkowski, M.D.
BOOK REVIEWS
MEDICAL SCHOOL SECTION
Dean's Letter ,
Dr. Mayer Appointed to Neurology Faculty-
Faculty Notes
Medical School Applicant Admission Policies — A Faculty Problem-
Dietrich C. Smith, M.D.
Annual Report of Department of Obstetrics and Gynecology-
ALUMNI ASSOCIATION SECTION
President's Letter
Class Notes .
Deaths
April. 1966
Medical education needs your dollars
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A Correlative Study of Chronic Arterial
Hypertension and Pregnancy
ISADORE G. ANCES, M.D., and ARTHUR L. HASKINS, M.D.
Toxemia of pregnancy is an acute
illness of pregnant women and has been
recognized as a clinical entity for several
hundreds of years. Toxemia of pregnancy
occurs in the United States with a fre-
quency of about six per cent of all preg-
nancies. The sun,-ival of the patient with
uncomplicated preeclampsia is 100%. The
survival of the patient with eclamptic tox-
emia is about 85% which is roughly equiv-
alent to the survival rate of the patient
with Stage I carcinoma of the uterine
cervix.
The perinatal mortality in preeclamptic
toxemia increases to 50% over average
rates. In eclamptic toxemia the perinatal
mortality increases approximately 200%.
Despite the frequency of the disease,
the long period of its clinical recognition,
the high maternal and fetal mortality,
toxemia of pregnancy remains a modern
day mystery. The etiology of toxemia of
pregnancy is unknown. The diagnosis of
toxemia of pregnancy is made by exclu-
sion, necessitating the consideration of
other disease processes causing hyperten-
sion, albuminuria, edema, and convulsions.
The treatment of toxemia of pregnancy is
symptomatic. Although the immediate
prognosis for mother and child is recog-
nizably poor, the remote prognosis for the
mother has been under debate for many
years.
In recent years some of our concepts
about toxemia have changed, particularly
in regard to the prognosis in toxemia.
From an era in which many considered
From the Department of Obstetrics and Gynecology,
University of Maryland School of Medicine.
that the recurrence rate of the disease was
negligible, we have now come to know
that there is a significant rate of recur-
rence.
In the consideration of the remote prog-
nosis of toxemia of pregnancy, an ex-
tremely practical problem, divided opin-
ions have indicated that toxemia of preg-
nancy does not cause permanent hyperten-
sion, does not predispose to permanent
hypertension or worsen permanent hyper-
tension.'' 2. 3 On the other hand, equally
voluble groups maintain that toxemia of
pregnancy may result in persistent hyper-
tension, may worsen permanent hypterten-
sion and may predispose to permanent
hypertension.''' ^' *> '' The incidence of per-
manent hypertension following toxemia of
pregnancy seemed to increase if pre-
eclampsia was present for a period of time
in excess of four weeks. This observation
was refuted by the "toxemia does not
cause permanent hypertension" school
with the observation that the patient who
developed permanent hypertension follow-
ing prolonged toxemia, was in reality an
individual with preexisting nonpregnancy
hypertensive disease.
The current study was undertaken with
a dedication to prove that toxemia of preg-
nancy does not predispose to permanent
hypertension nor cause permanent hyper-
tension. It was reasoned that since toxemia
of pregnancy occurs only in pregnant
women, that an analysis of pregnant and
nonpregnant populations, were they to
show similar rates of hypertension, would
indicate that toxemia does not influence
April, 1966
17
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
post pregnancy hypertensive rates. It was
anticipated that the nonpregnant popula-
tion and pregnant population would have
identical incidences of permanent arterial
hypertension.
A trial run with the obstetrical data at
the University of Maryland Hospital indi-
cated that such a study would be feasible.
The aid of the Obstetrical Statistical Co-
operative was then enlisted since the
grouping of data required a relatively large
sample for significance.
Material
The clinical material was collected
through the Obstetrical Statistical Coop-
erative* for the years 1951-1960. The total
sample of 288,874 pregnancies was ana-
lysed. The pregnancies were grouped ac-
cording to age ; less than 20 years, 20-29
years, 30-39 years and 40 and over years.
Pregnancies were also grouped according
to parity; para 0, para 1-3, para 4-6, and
para 7 and over as in Table I. The material
Table 11
Parity
1-3
4-6
7 +
Age
in Years
Total
<20
24,497
10,943
76
11
35,527
20-29
56,980
101,550
13,664
1,412
173,606
30-39
9,872
46,391
13,673
4,518
74,454
40 +
560
2,508
1,213
1,006
5,287
TOTAL
91,909
161,392
28,626
6,947
288,874
Total study sample for occurrence of
hypertension relative to pregnancy.
* The obstetrical statistical cooperative was organized
through the eflforts of Dr. Schuyler Kohl. Dr. D. Frank
Kaltreider has been responsible for the continuation of
the program at Maryland. The cooperative has a mem-
bership of 18 hospitals. Each obstetrical department
reports its annual experience to the central organization
at the State University of New York, Downstate Med-
ical Center. The accumulated data is stored and made
available to member institutions upon request.
Parity
1-3
4-6
7-1-
Age
in Years
Total
<20
393
173
3
569
20-29
678
1,515
547
80
2,820
30-39
278
1,317
727
326
2,648
40-1-
40
160
110
78
388
TOTAL
1,389
3,165
1,387
484
6,425
Occurrence of hypertension
relative to age and parity.
was viewed according to non-white and
white populations. The definition of hy-
pertension is that used by the Obstetrical
Statistical Cooperative of arterial pressure
of over 138 systolic and 88 diastolic. The
occurrence of hypertension is shown in
Table II. Significance of data was assessed
by the Chi-squared statistical method.
Results
The non-white population consisted of
30% of the sample. Preliminary evalua-
tion of hypertensive trends indicated a
greater incidence of hypertension in the
non-white population than in the white
population. The correlative trends of age
and gestation were similar in both. The
groups were combined to insure signifi-
cance.
To test the validity of the material in
the reflection of established trends in the
development of hypertension, the incidence
of hypertension relative to patient age was
plotted as in Figure 1. There is no increase
in hypertension in the younger age groups
to 29 years. At the level of 30-39 years a
trend toward increasing hypertension is
initiated and is further established in the
40 and over year age group.
With proof that our data reflected at
least one established factor in the develop-
18
Vol. 51, No. 2
ANCES, HASKINS— ARTERIAL HYPERTENSION AND PREGNANCY
A9t<20 eO-29 30-39 40*-
Fiff. 1. The incidence of hypertension relative
to patient age.
Fig. 2. The incidence of hypertension relative
to patient parity.
*gl <20 20-89 50-39 40*
Tig. 3. The incidence of hypertension relative
to patient parity and a^e.
Fig. 4. The incidence of hypertensic
to patient parity and age.
merit of hypertension, the next step was
to show that pregnancy and its inevitable
comphcation of toxemia did not reflect a
similar increase in hypertension with in-
creasing numbers of pregnancies.
Accordingly the data was arranged to
compare parity and incidence of hyperten-
sion as indicated in Figure 2. The nulli-
parous patient showed the least hyperten-
sion, the para 7 and over group showed
the greatest incidence of hypertension,
with the intermediate groups indicating
the same trend. Since it was not possible
to separate the age factor in this graphic
analysis from increasing parity, it was
assumed that the trend of increasing hy-
pertension could be the result of influence
of aging in itself.
The data was then arranged to compare
nulliparous hypertension and parous hy-
pertension at all age levels. As indicated
in Figure 3, the incidence of hypertension
was greater in the parous patient than in
the nulliparous patient at all age levels
with the exception of the age group at less
than 20 years. At this age, the incidence
of hypertension in both groups, regardless
of the status of parity, was 1.6%.
Finally, in an attempt to ascertain possi-
ble influences of increasing parity on the
incidence of hypertension, each of the four
parity groups were tabulated and plotted
as indicated in Figure 4. At each level
there is a trend toward increasing hyper-
tension with increasing parity, although it
is quite apparent that this trend is not
established until the level of para 4 and
over is reached. There is no real difference
in the incidence of hypertension between
the para and para 1-3 groups at any age
level.
April, 1966
19
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Conclusions
It is immediately apparent that the
premise as originally defined: toxemia
of pregnancy or pregnancy is not associ-
ated with an increased rate of permanent
hypertension, could not be proved. In fact,
the data analyzed indicated that quite the
contrary was true. With increasing preg-
nancies, the rate of permanent arterial
hypertension increased in all age groups
over 19 years. The trend was most marked
in the 20-29 and the 30-39 years groups.
It is of interest to note that Schreier, et
al.,^ observed that most women developing
permanent elevation of blood pressure did
so after three pregnancies and at least two
episodes of toxemia. Our data confirms
that trends toward permanent hyperten-
sion are not established until parity or
greater than three has been attained.
Aging and its effect on the development
of hypertension are well known. The data
presented indicates that the age factor is
easily demonstrable. Correction of the
data for the age factor was accomplished.
Comparison of the number of patients in
our data who probably had toxemia of
pregnancy to the corrected hypertension
rate indicates that the incidence of perma-
nent hypertension following toxemia of
pregnancy could be 11.1%. This compares
quite favorably to the findings of Schreier,
et al., in which it is indicated that 11.3%
of 239 patients with toxemia of pregnancy
were found to have permanent hyperten-
sive disease.
The data and analysis presented is at
variance with the conclusions of others
who consider that pregnancy and toxemia
of pregnancy is never followed by perma-
nent arterial hypertension.
Summary
Data obtained through the Obstetrical
Statistical Cooperative provided 288,874
pregnancies for study. The pregnancies
were divided into parity and age groups.
Comparisons of the various age and parity
groups indicated an increased incidence of
permanent hypertension with increasing
age and parity.
References
1. IsENHouR, C. E., KuDER, K., and Dill, L.
V. : The Effect of Parity on the Average Blood
Pressure and on the Incidence of Hypertension.
Am. J. M. Sc. 203:333, 1942.
2. Barnes, J., and Browne, F. J. : Incidence
of Hypertension in Nulliparous and Parous Wo-
men in Relation to the Remote Prognosis of
Toxemia of Pregnancy. /. Obst. & Gynec. Brit.
Em/^.. 52:1, 1945.
3. DiECKMAN, W. J., Smitter, R. C, and
RvNKiEwicz, L. : Pre-Eclampsia — Eclampsia
Does Not Cause Permanent Vascular Renal Dis-
ease. Am. J. Obst. & Gynec, 64:850, 1952.
4. Harris, J. W. : The After-Effects of Late
Toxemias of Pregnancy. Bull. Johns Hopkins
Hasp., 35:103, 1924.
5. Peckham, C. H. : Chronic Nephritis Fol-
lowing Eclampsia. Bull. Johns Hopkins Hasp.,
45:176, 1929.
6. Schreier, P. C, Adams, J. Q., Turner,
H. B., and Smith, M. J. : Toxemia of Preg-
nancy as an Etiological Factor in Hypertensive
Vascular Disease. /. A. M. A., 159:105, 1955.
7. Chesley, L. C, Annitto, J. E., and Cos-
GROVE, R. A. : Prognostic Significance of Recur-
rent Toxemia of Pregnancy. Obst. & Gynec,
23:874, 1964.
20
Vol. 51, No. 2
Beiiiffii Localized Fibrous Mesollielioma of Pleura
Clinical ('onsiderations and Report of a Case
JOSEPH MIUETT, M.D.*
MESOTHELIOMAS of the pleura for
a great many years had been considered
a pathological curiosity. They were a
perplexing group of tumors and there
were numerous opinions regarding their
clinical, roentgenological and pathological
features, particularly the latter.
Klemperer and Rabin, i and Stout and
Murray,- and Stout and Humadi^ made
notable contributions toward the patho-
logical clarification of these tumors.
Clagett et al^ and Foster and Ackerman^
aided in delineating some of the clinical
features of this pathological entity.
The purpose of this report is to call
attention to the clinical features of this
relatively rare condition. Rubin'' has
stated that the pleura is rarely the site
of primary tumors. Harrison, '' CecU and
Loeb* and Ackerman and Regato** devote
scarcely one paragraph to these con-
ditions, while Roberts^" mentions them
not at all. It is apparent that the path-
ologist and the surgeon have had the
greatest pre-occupation with this con-
dition.
Case Report
A 53 year old man, complained of a grippy
feeling of several days duration. There were
no other signs or symptoms. The system re-
views were negative and there was no weight
loss. There were no previous illnesses or
hospitalizations. He did not smoke. Eighteen
months ago a routine physical examination, in-
cluding blood chemistries, electrocardiograph,
and fluoroscopy were normal.
Read before the section on Internal medicine,
Nassau Hospital, July 14, 1965
* Associate attending physician, department of
internal medicine, Nassau Hospital, Mineola,
N. Y.
He was six feet tall and weighed 180 lbs.
Physical examination showed only a slightly
injected throat. On fluoroscopy of the chest
a smooth mass, which moved with respiration,
was seen in the right hemithorax lying on the
diaphragm adjacent to the mediastinum.
Radiologic study revealed a large lohulated
mass approximately 10 cm. in diameter in the
right posterior thorax distinct from the con-
tour of the posterior aspect of the diaphragm.
The lesion did not involve the ribs (see Figs.
1 and 2).
The patient entered Nassau Hospital on
December 20, 1964. The chemistries, including
the blood sugar, the blood count and urine,
roentgenographs of the abdomen, large in-
testine and kidneys, and the electrocardiograph
Fisr. 1. AP view of chest.
April, 1966
21
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Fie. 2. Lateral X-ray of chest.
Fig. 3. Lateral tomogram of chest.
were all normal. Tomograms of the chest
clearly delineated the mass in the right chest
(Fig. 3).
Pulmonary function studies revealed a slight
diminution in lung volume but there was good
ventilatory function. Bronchoscopy was en-
tirely normal and there was no compression
of the bronchial tree. Sputum collected and
later smeared showed an abundance of mucus,
a few superficial squamous cells and a number
of histiocytes and polynuclears. Tumor cells
could not be found.
On December 29, 1964 the patient was
operated upon. The chest was entered through
a right posterior lateral incision in the seventh
interspace. A large encapsulated tumor was
found in the pleural cavity, attached to the
visceral surface of the right lower lobe by
a pleural-like band. This was simply divided,
the tumor easily removed, and a tube was
inserted into the pleural cavity. The patient
stood the procedure well.
Follow-up chest films showed the tube in
place, resection of one rib, some slight eleva-
tion of the right diaphragm, the lungs well
expanded and no evidence of pleural fluid.
Pathologic Studies
Specimen: Mediastinal Tumor.
Gross: The specimen was a bulky somewhat
pyramidal-shaped mass weighing 462 grams and
measuring 13.5 x 13 x 7 cm. (Fig. 4). The
outer surface was for the most part grayish-
pink, smooth and glistening. However there
were few irregular zones where the glistening
capsule had been denuded. There were other
areas of coarse nodularity. The entire mass had
a soft, rubbery consistency. Repeated incisions
disclosed a solid lobulated pale yellowish-tan
glistening tumor tissue. The cut surface had a
mucinous feel. One of the incisions passed
through a 4 X 2.2 cm. sharply demarcated
pale yellow soft zone of necrosis. There was
considerable variation in the size of the lobules,
some being but a few mms. in diameter. This
lobular pattern was produced by shallow
branching fissures (Fig. 5).
Microscopic: Numerous sections removed
from various areas showed a tumor composed
almost entirely of small spindle shaped cells,
some arranged in fascicular pattern. There
was varying density of the cells. In some areas
they were crowded together, in others they
22
Vol 51. No. ?
MILLETT— MESOTHELIOMA OF PLEURA
Fig. 4. Fib
bulky tumor.
were more loosely arranged. In all parts of
the tumor there were varying amounts of
collagen fibrous tissue arranged in strands. In
a few of the sections there were split-like
spaces principally distributed at the periphery
of the growth. These spaces were lined by
cuboidal or flattened cells suggesting meso-
thelium. TTie sections through the necrotic
zone showed a sharp demarcation between the
dead tissue and the adjacent viable growth.
There was a zone of dense collagen fibrous
tissue at the periphery of the necrosis. A small
venous channel contained an organizing throm-
bus. All of the tumor cells were uniform in
size. The nuclei lacked any evidence of malig-
nant change. Mitoses could not be found
(Fig. 6 and 7).
Diagnosis was a benign type of mesothelioma
of the pleura.
Several slides were sent to Arthur Purdy
Stout, M.D., department of surgical pathology.
College of Physicians and Surgeons of Columbia
University, for consultation, who, in personal
communication stated — "This tumor is a
characteristic benign fibrous mesothelioma of
the pleura. It has the usual gross features and
the 'patternless pattern' that are so distinctive
of mesothelioma."
Diagnosis: Benign fibrous mesothelioma of
the pleura.
The patient made an uneventful recovery
and left the hospital on lanuary 7, 1965. He
was last seen in the office on February 1, 1966.
Fiz. 6. Photomicroeraph of tamor (100 X).
April, 1966
23
BULLETIN OF THE SCHOOL OF MEniCINE, UNIVERSITY OF MARYLAND
,y
j*' »>. it, '-' ''ff.-J, *'^>/* • i
Fie. 7. Photomicrograph of tumor (400 X).
Note Fibroblasts
He was back at work on full duty and had no
complaints.
Discussion
Benign fibrous mesothelioma is a
localized, well encapsulated, sometimes
lobulated fibrous tumor of the pleura,
arising mainly from the visceral pleura,
occasionally from the parietal pleura and
rarely from the pleura of the interlobar
fissures. It projects outward into the
pleural cavity held by a stalk. This
soUtary type is usually benign. Micro-
scopically it contains collagen fibrous
tissue, spindle shaped cells and meso-
thelial cells and is histologically benign.
Its counterpart, the diffuse type of the
pleural mesothelioma, is highly maUg-
nant. It arises from the pleura but invades
sub-pleurally. Microscopically it is histo-
logically malignant and contains epithelial
cells and mitotic figures. This type of
tumor metastasizes. A third type is a
localized tumor, well encapsulated, but
which may contain some malignant cells.
This should be classified as a mixed type
of tumor, but it is benign in action. ii
Mesotheliomas may occur in other
areas of the body — the peritoneum, ^^ tjjg
male and female urogenital tracts — the
epididymus, the vas, the round ligament,
Fallopian tube, canal of Nuck, and on
the serosa of the uterus."' ^^ We are not
concerned with these tumors except they
may possess in common with the fibrous
and diffuse mesotheliomas of the pleura
the property of producing hypoglycemia,
which will be discussed later.
The incidence of pleural mesotheliomas
has been difficult to evaluate because of
the terminology and conflicting descrip-
tions applied to these tumors prior to the
work of Klemperer and Rabin and Stout
and Murray. They have been called and
described variously as fibromas, fibrosar-
comas, myxosarcomas, leiomyosarcomas,
giant sarcomas of the pleura, sarcoma-hke
tumors and endotheliomas. Saccone and
Coblentzi^ reported 1.1 per thousand
cases in 45,000 autopsies. Clagett et al
collected 24 cases of fibrous mesothelio-
mas over a 20 year period at the Mayo
Clinic in which surgery had been done.
Clagett's group of 24 cases, Benoit and
Ackerman's^^ 17 cases, and Stout and
Humadi's 1 8 cases revealed a mean age of
approximately 50 years, with several cases
occurring as early as age 12 years and as
late as 70 years. On an average the
number of females was slightly higher
than the males.
Clinically these lesions are first detected
on casual x-ray examination or fluoro-
scopic chest examination, all as part of
routine general examinations. This, inci-
dentally, has made it difficult to calculate
the age of the tumor in these asympto-
24
Vol. 51. No. 2
MILLETT— MESOTHELIOMA OF PLEURA
matic cases unless one has a point of
reference as in the present reported case
where a fluoroscopic examination of the
chest two years prior to the present one
was entirely negative. However, in some
reported instances the tumor has been
tcnown to have existed for as long as
nine (9) years. ^'
Local chest symptoms, when present,
are relatively rare. They are related
mainly to mechanical interference in the
chest itself. Thus there has been noted
a sense of heaviness on the side of the
lesion. When large enough the tumor
may produce dyspnea and even a non-
productive cough. Occasionally blood
streaked sputum is noted. Chest pain
may occur when the dome of the fibrous
tumor may attach itself to or rub on the
pleura opposite to the point of attach-
ment creating irritation and fibrous ad-
hesion. Pleuritic pain may also be due
to pressure on the ribs with erosion of the
ribs. Distended neck veins may occur.
Hawthorne and Probese" reported dys-
phagia and peripheral edema in a 40 year
old woman. They attributed this to local
pressure phenomena since these symptoms
disappeared when a 1,500 gram fibroma
of the pleura was removed from her right
chest. Rarely they may cause cardiac
failure by mechanical pressure. ^^
Physical signs in the chest itself may
not be present — depending on the size
of the tumor and also on the size and
the character of the patient's chest in
relation to the tumor. When present, an
area of dullness may be percussed out.
These signs may be obscured or confused
by fluid, serous or hematogenous. While
effusions generally occur with malignan-
cies, they have occurred with benign meso-
theliomas."' ^^
There was no weight loss noted with
the benign fibrous mesotheliomas of the
pleura. Some patients have had present-
ing complaints of chills and fever which
have been present for varying lengths of
time. The origin of these symptoms is
obscure. It has been postulated in some
instances that these may be due to areas
of lung compression and pneumonitis.
When generalized arthraligias are present,
which are not uncommon with fibromas
of the pleura, the fever may very well
accompany these joint pains and swell-
ing. While arthralgic symptoms have been
noted with other pulmonary tumors,-^
Clagett found that 16 out of his 24 cases
had symptoms referrable to joints and
in many instances these were the com-
plaints that brought the patient to the
physician. The articular symptoms had
been present for more than a year. The
hands, ankles, wrists, elbows, and knees
were involved with varying degrees of
disability. Benoit and Ackerman also
described these symptoms.
Clubbing of the fingers and toes was
also seen in association with articular
symptoms and also as a sign by itself.
Where joint pains were present without
associated clubbing of the fingers, it was
difficult to distinguish the patient's con-
dition from rheumatoid arthritis. When
the associated benign fibrous mesotheli-
oma of the pleura was removed there was
a rapid disappearance of the articular and
arthralgic symptoms followed by a slow
regression and final disappearance of the
clubbing in every case. These symptoms
also seem to be dependent on the size
of the tumor and were not seen unless
the tumor weighed in the vicinity of 450
grams.
An unusual symptom associated with
large slow growing tumors in various
parts of the body, well encapsulated, hav-
ing the microscopic appearance of fibro-
mas, mesotheliomas or sarcomas of vari-
ous types has been severe hypoglycemia.
These tumors have been grouped as fibro-
genic or mesodermal tumors associated
with hypoglycemia and the syndrome of
April, 1966
25
BULLETIN OF THE SCHOOL OF MEDICINE. UNH'ERSITY OF MARYLAND
"large non-pancreatic tumors with hypo-
glycemia" is being recognized as a clinical
entity. Cases have been reported where
patients have been admitted in a maniacal
condition or in states of insulin shock
with blood sugars as low as 10-12 per cent
with the finding of these associated
tumors. Injections of glucose have given
temporary relief, but cure was only ob-
tained by extirpation of the tumor. 22 A
growing literature on this subject is avail-
able. ^^^ '^*- 2^' 26 The mechanism by which
these tumors induce hypoglycemia is not
definitely known.
Roentgenographically solitary pleural
mesotheliomas of the pedunculated variety
may be easy to recognize according to
Berne and Heitzman.^'' They have stated
that a pedunculated pleural mass has the
ability to move about the pleural space
freely if very little surface of the intra-
pleural mass is attached to either pleural
surface. Because of the remarkable mo-
bility of these tumors a striking change
in the shape and density of the shadow
they produce can occur on comparably
projected and exposed roentgenograms.
They report 2 cases in which a pre-opera-
tive diagnosis of a pedunculated tumor
was made on this basis and proven at
surgery. Occasionally, the localized tumor
is huge and opacifies the major portion
of a hemithorax simulating a massive
effusion. 16 Occasionally pneumothorax
may be helpful in delineating a localized
tumor.
Other attempts at pre-operative diag-
nosis of the benign pleural fibroma have
not been of great help. Cell block studies
on aspirated chest fluid where present
have been negative. Bronchoscopy has
been of little use in these extrapleural
tumors. Bronchial washes have yielded
negative cytological studies. Compression
of the bronchial tree, when present, does
not necessarily tell us whether the dis-
tortion of the bronchial tree is due to
intrapleural or extrapleural pressure.
Angiocardiography may be of use in
doubtful cases in attempting to eliminate
pericardial and great vessel involvement
and to distinguish these tumors from a
variety of other intra-thoracic tumors.
The final diagnosis lies in the hands
of the surgeon and the pathologist. At
operation, where an encapsulated, lobu-
lated tumor is found hanging from a
pedicle usually from the visceral pleura,
sometimes from the parietal pleura and
rarely from an interlobar area, a clinical
diagnosis of benign fibrous mesothelioma
of the pleura can be made with relative
certainty. Treatment is comparatively
easy in these cases. The pedicle is tied
ofl" and the tumor is delivered through
the thoracotomy opening. Grossly these
tumors vary in size, some being reported
as weighing as much as 5,000 grams.
Microscopically the benign pleural fibro-
mas will be composed of spindle shaped
cells, areas of collagen tissue, areas of
necrosis, and tumor cells of mesothelial
origin which lack mitosis or any evidence
of malignant change. Prognosis is, there-
fore, good.
Summary
1. Primary neoplasms of the pleura
are divided into two main groups, one
of benign solitary localized pedunculated
growths, and the other a difi'use malig-
nant type involving the entire pleura and
associated with metastasis. The mixed
encapsulated type of tumor usually acts
as a benign fibroma.
2. Many of the cases of benign fibrous
mesotheliomas of the pleura are asympto-
matic and are picked up on routine chest
x-rays or fluoroscopy.
3. A definitive pre-operative diagnosis
of benign fibroma of the pleura may be
difficult to make, but where an intra-
thoracic tumor is present associated with
a history of chills, fever, migratory swell-
26
Vol. 51. Nc.
MILLETT— MESOTHELIOMA OF PLEURA
ing and pain in the joints, and clubbing
of the fingers, the clinician should be
aware of and consider the possibility of
localized fibrous mesothelioma.
4. X-rays of the chest taken with the
patient changing his position may help
diagnose a shifting pedunculated tumor.
5. The association of hypoglycemia
and fibrogcnic mesotheliomas in the chest,
or elsewhere in the body, is stressed as
a finding worthy of the clinician's interest.
501 Fulton Avenue,
Hampstead, New York
Bibliography
1. Klemperer. p. and Rabin, C. B. Pri-
mary Neoplasms of the Pleura. A Report of
Five Cases. Arch Piilh 11:22,5, 1931.
2. Stout. A. P. and Murray, M. R. Local-
ized Pleural Mesothelioma. Arch Path 34:9S\,
1942.
3. Stout. A. P. and Humadi. G. M. Solitary
(Localized) Mesothelioma of the Pleura. Ann
Surg 133:50. 1951.
4. Clagett. O. T., McDonald, J. R, and
Schmidt. H. W. Localized Fibrous Mesotheli-
oma of the Pleura. J Thorac Cardiov Surg
24:2n, 1952.
5. Foster, E. A. and Ackerman, L. V.
Localized Mesotheliomas of the Pleura. Amer
J Clin Path 34:349. 1960.
6. Rubin, E. H. Thoracic Diseases. W. B.
Saunders Co., p. 542, 1961.
7. Harrison, T. R. Principles of Internal
Medicine. Blakiston Div. McGraw Hill, p.
1400, 1958.
8. Cecil. R. L. and Loeb, R. F. Textbook
of Medicine. W. B. Saunders Co., p. 1005,
1959.
9. Ackerman, L. V. and Regato, J. A.
Cancer, C. V. Mosby, p. 447, 1954.
10. Roberts, H. J. Difficult Diagnosis. W. B.
Saunders Co., 1959.
11. Foster, E. A. and Ackerman, L. V.
Localized Mesotheliomas of the Pleura. Amer
J Clin Path 34:349, I960.
12. Stout, A. P. Solitary Fibrous Meso-
thelioma of the Peritoneum. Cancer i.-820,
1950.
13. Evans, N. Mesothelioma of the Epidi-
dymus and Tuncia Vaginalis. J Urol 50:249,
1943.
14. Masson. p., Riopelle, J. L. and
Simard, L. G. Le Mesothelioma Benin de
la Sphere Genitale. Rev Cancid Biol 1:120,
1942.
15. Saccone, a. and Coblentz, A. Endo-
thelioma of the Pleura with Report of Two
Cases. Amer J Clin Path 13:186, 1943.
16. Benoit, Jr., W. H. and Ackerman,
L. V. Solitary Pleural Mesotheliomas. /
Thonic Cardiov Surg 25:346, 1953.
17. H\wthorne, H. R. and Frobese, A. S.
Benign Fibroma of the Pleura. Dis Chest
17:588. 1950.
18. Sarot, I. A. Fibrosarcoma of the
Pleura Mechanically Causing Congestive Heart
Failure: Successful Surgical Removal. Quart
Bull Sea View Hosp 70.109, (July) 1948.
19. Ehrenhaft, J. L., Sensenig, M. and
Lawrence, M. S. Mesothelioma of the Pleura.
J Thorac Cardiov Surg 40:393, 1960.
20. Heaney, J. P., Overton, R. C. and
DeBakey. M. E. Benign Localized Pleuro
Mesothelioma. / Thorac Cardiov Surg 34:553,
1957.
21. WiERMAN, W. H., Clagett, O. T and
McDonald, J. R. Articular Manifestations of
Pulmonary Diseases; An Analysis of Their
Occurrence in 1024 Cases in which Pulmonary
Resection was Performed. JAMA 755.1459,
1954.
22. Miller, D. R. at al. Hypoglycemia
due to Non-pancreatic Mesodermal Tumors.
Ann Surg 150:684, 1959.
23. Nesbitt, K. a., Boswell, J. T. et al.
Malignant Mesothelioma Associated with Hypo-
glycemia. Amer J Clin Path i0.148, 1958.
24. Friesan, S. R. and Miller, D. R. Fibro-
genic Mesodermal Tumors. An Unusual Case
of Hyperinsulinism. Amer J Surg 99:420, I960.
25. Nevins, D. B. and Friedman, N. B.
Mesotheliomas and Extra-Ovarian Thecomas
with Hypoglycemic and Nephrotic Syndromes.
Cancer 72.1263, 1959.
26. SCHOLZ, D. A., WooLNER, L. B. and
Priestly, J. T. Spontaneous Hypoglycemia
Associated with Fibrogenic Tumor, Report of
Two Cases. Ann Intern Med 46:196, 1957.
27. Berne, S. A. and Heintzman, R. E.
The Roentgenologic Signs of Pedunculated
Pleural Tumors. Amer J Roentgen 87:892,
1962.
April, 1966
27
Chromosomal Mosaicism in Gonadal Dysgenesis
Report of a Case
HANS-DIETER TAUBERT, M.D., ERICA F. MOSZKOWSKI, M.D.*
THE ENTITY of primary amenorrhea,
short stature, webbing of the neck, and
cubitus valgus, has become known as
Turner's syndrome. It is often associated
with multiple congenital anomalies, par-
ticularly those of the cardiovascular
system. The gamut of this syndrome may
range from the classical Turner's syn-
drome with severe defects to the so-called
pure gonadal dysgenesis, ^^ where the
pathology is Hmited to the gonads. The
common pathognomonic denominator is
the absence of germ cells. The ovaries
consist merely of streaks of stromal tissue
with no ova being present. Ford^ recog-
nized in 1959 that this syndrome is
characterized by the absence of one X
chromosome, except for rare cases.^^ Of
particular theoretical and practical interest
are those cases where 2 stem-Hnes of cells
are present. One contains the normal
modal number of chromosomes, while
the other is hypoploid due to the lack of
one X chromosome. Chromosomal
mosaicism with XO/XX configuration of
the sex chromosomes is next to XO the
most common finding in gonadal dysgene-
sis. Miller was recently able to review
over 25 reported cases. i- 3. 7, s, lo, n. 12,
17. 18 jt J5 tjjg purpose of this paper to
report and discuss another case of gonadal
dysgenesis with chromosomal mosaicism.
Case Report
C. J., U. H. #29-17-32. This 15-year-old
Negro girl was first seen in the Gynecologic
Endocrine Clinic on June 30, 1964. Her chief
complaint was stunted growth, primary am-
enorrhea, and minimal development of the
secondary sex characteristics. Her height was
142.5 cm. She weighed 107 lbs.; the span was
150 cm. On general inspection the patient had
a short neck with a trace of webbing. The
chest was shield-like and the nipples wide-
spaced, small and flat. There was no areolar
pigmentation. Axillary and pubic hair was
sparse (Table 1, Fig. 1). Her hands were
remarkably long, with spidery fingers, and
hyperextensible joints. The palms were spoon-
shaped and could not be completely flattened.
The fourth toe on the right foot was short.
Table 1 — Malformations and Laboratory Data
A. EXTERNAL MALFORMATIONS
Webbing of the neck
trace
Low implantation of the hair
present
Short fourth metatars
al bone
present
Epicanthic folds
present
Cubitus valgus
present
Arachnodactyly
present
Spoon-shaped palms
present
Shield-like chest with
wide
spaced nipples
present
Pigmented naevi
absent
B. RADIOLOGIC MALFORMATIONS
Sella turcica normal
Bone age normal
Osteoporosis absent
C. FAMILY
Number in sibship
Age of mother at birth
Age of father at birth
Malformations in family
Consanguinity in family
X-ray. viral disease, etc. around
conception
D. LABORATORY DATA
Vaginal cytology
Sex-chromatin, rt. buccal ca'
Sex-chromatin, It. buccal ca^
"Drumsticks"
infignratif
number
* From the University of Maryland School
of Medicine, Department of Obstetrics and
Gynecology.
Total urinary gonadotrophir
17-ketosteroid excretion
Protein-bound iodine
Xga Proposita
Mother
Sister
Dermatoglyphics
absent
absent
no estrogen effect
247c positive
18% positive
53/1000
XO/XX
44-0
45-34 (51.47c)
46-32 <48.67r)
47-0
more than 50
mu/24 hrs.
2 mg./24 hrs.
7.7 mcg7o
Xga (4-)
Xgra <+)
Xga (+)
compatible
28
Vol. 51, No. :
TAUBERT, MOSZKOWSKI— CHROMOSOMAL MOSAICISM
Fie. 1
tion of the vaginal mucosa. Adnexal structures
could not be palpated.
Laboratory Data: On August 5, 1964, 26%
of the buccal mucosal cells were positive for
se.x-chromatin. On March 2, 1965, a repeat
examination of both the right and left buccal
mucosa showed 24% chromatin-positive cells
on the right including 6% very small ones.
The smear on the left revealed the presence
of Barr bodies in 18% of the cells with 4%
being small ones. Fifty-three polymorpho-
nuclear leukocytes per 1,000 were found to be
positive for the presence of "drum sticks."
Vaginal cytology from June 30, 1964, did not
show any evidence of estrogenic stimulation.
Chromosomal Analysis: White blood cells
were cultured by a modification of the method
of Moorhead.i-' Si.xty-six cells were suitable
for analysis. Thirty-two showed the normal
modal number of 46 chromosomes. The re-
maining 34 cells lacked one of the large sub-
metacentric chromosomes of group 6-12
(Denver Classification)^ or C (Patau). is This
was interpreted as mosaicism of the X-chromo-
somes with the following two stem-lines:
45 (XO)/46 (XX).
Gonadotrophin excretion: The 24-hour value
for total urinary gonadotrophins exceeded 50
mouse-units (more than adult normal).
The 17-ketosteroids were 2 mg./24 hour
urine.
X-ray studies: The sella turcica was normal.
The bone age was compatible with 14.5 years.
Osteoporosis was not evident.
Dermatolglyphics:'^^ The axial triradius was
in t' position. The adt-angle exceeded 50°.
All digits with the exception of digits V sinister
showed ulnar loops. The latter had a whirl.
The total digital ridge count was 144; the
ridge count was 144; the ridge count between
triradius a and b was 58. For comparison the
same data were obtained from her younger
sister: Axial triradius t, adt-angle 45°, digital
ridge count 132 (normal range); a-b ridge
count 45 (normal); whirls on digitus I and 11
right and left, and digitus III on the right.
The remaining finger had ulnar loops.
No cardiac anomalies were found. The
patient had poor vision in one eye due to
strabismus. Color vision was normal.
Examination with the patient under anes-
thesia disclosed a small cervix, atrophic labia,
and an intact hymen. There was no stimula-
Comment
Lack of germ cells in the gonads and
loss of one X-chromosome in early de-
velopment are the notable features of this
entity. It appears that segregation and
April, 1966
29
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
migration of the primitive germ cells from
the hind-gut to the germinal ridge depends
upon the presence of 2 X-chromosomes.''
Embryonal cells do not show many
chromocenters prior to day 16-18 of de-
velopment. After segregation of the primi-
tive germ cells, however, one of them be-
comes genetically inactive and as such
the chromocenter or the Barr body.^ Fail-
ure of the primitive germ cells to arrive at
the germinal ridge seems to arrest the
gonad at the stage of the primitive, in-
different medullar Any other cause
which will prevent this migration will have
the same result in gonadal development.
This explains chromatin-positive cases of
gonadal dysgenesis with normal 46/XX
karyotype.
In a case as ours one has to assume that
the germ cells descended from a stem-line
with the karyotype 45/XO. Examination
of more than one tissue could possibly
have uncovered an even more complex
system of multiple mosaicism. Differences
in the percentages of chromatin-positive
cells from either buccal mucosa have been
observed.*
The observed difference of 18% and
24% respectively cannot be considered
significant in this context.
Pre-zygotic maternal or paternal non-
disjunction during the first or second
meiotic division is thought to be the cause
for aneuploid states such as gonadal dys-
genesis, Klinefelter's syndrome, autosomal
trisomies, et cetera. In contrast, chro-
mosomal mosaics are believed to origi-
nate from faulty division of the zy-
gote.^ * ^ Mitotic non-disjunction or loss
of an X-chromosome due to anaphase lag
have been postulated as possible mecha-
nisms.
The maternal or paternal origin of the
X-chromosome in such individual can be
studied by investigating sex linked traits.
Color blindness, glucose-6-phosphate-
dehydrogenase deficiency, and Duchenne's
atrophy were not applicable in the case
presented. Determination of the Xg blood
group can be most helpful in this aspect,
since presence of the Xg" (-f) allele
assures dominance of the trait. ^^^ Since
all accessible members of the family were
Xg" ( + ), no further information could
be gained in this aspect.
Mitotic non-disjunction at the first
cleavage division would have resulted in
an X/XXX embryo. The triple-X stem-
line would be recognizable by virtue of
the supernumerary chromosome. A num-
ber of buccal smear cells would contain
2 Barr bodies, representing 2 inacti-
vated X-chromosomes. The most likely
explanation is that an XX zygote lost
one of the sex chromosomes during ana-
phase at the first cleavage division, re-
sulting in equal proportions of XO/XX
cells as observed. This cell type could
also have originated in mitotic non-dis-
junction at the second cleavage division.
However, one would have to assume that
the zygote was originally XO, and the
proportion between the 2 cell fines should
not be even.
Dermatoglyphic examinations have
been used successfully in characterizing
various congenital anomalies. The con-
figuration of the dermal ridges are laid
down at a very early stage of develop-
ment, around the third month. i* The
propositus showed some of the typical
findings: t' position of the axial triradius,
increased adt-angle, and an increased
dermal ridge count.
Treatment
The patient was placed on estrogen-
substitution therapy with the aim to in-
duce development of the secondary sex
characteristics, and hopefully to induce
further growth. Figure 2 attests to
the effectiveness of this regimen as to the
30
Vol. 51, No. 2
TAUBERT. MOSZKOWSKI— CHROMOSOMAL MOSAICISM
former, e.g., after 6 months of 0.2 mg. of
stilbestrol, q.d. No further growth oc-
curred. Cyclic therapy will be instituted
for induction of menstrual cycles as soon
as the development of the genitalia is
suflScient.
Summary
A 15-year-old-Negro girl presented
with stunted growth, primary amenorrhea,
and lacking development of the secondary
sex characteristics. Chromosomal analy-
sis confirmed the clinical impression of
gonadal dysgenesis. The karyotype pre-
sented as a mosaic containing two cell
lines: 45 (XO)/46 (XX). Estrogenic
replacement therapy resulted in satis-
factory development of the secondary sex
characteristics. The origin of the chromo-
somal defect was discussed.
Acknowledgment
The help of Miss E. Jahn of the Baltimore
Rh-Typing Laboratory in obtaining the Xg-
Typing is gratefully acknowledged.
References
1. De La Chapelle, A: Cytogenetical and
Clinical Observations in Female Gonadal Dys-
genesis, Acta Endocr., 65:1, 1962 (Suppl.).
2. Editorial: A Proposed Standard Nomen-
clature of Human Mitotic Chromosomes, Amer.
J. Human Genet., i2.-384.
3. Ford, C. E., Jones, K. W., Polani, P. E.,
De Almeida, J. C, and Bricgs, J. H.: A Sex
Chromosome Anomaly in a Case of Gonadal
Dysgenesis, Lancet, 7. 7 11, 1959.
4. FROLA^ro, A., Johnsen, S. G., Andersen,
P., Dein, E., Sanger, and Race, R. R.: Non-
disjunction and XXY Men, Lancet, 2.'1121-22,
1963.
5. Griboff, S. O. and Lawrence, R: The
Chromosomal Etiology of Congenital Gonadal
Defects, Amer. J. Med., iO.-544-563, 1961.
6. Grumbach, M. M. and Morishima, A.:
Sex Chromatin and the Sex Chromosomes:
On the Origin of Sex Chromatin from a Single
X Chromosome, Acta CytoL, 6;46-60, Jan. -Feb.
1962.
7. Jones, H. W., Ferguson-Smith, M. A.,
and Heller, R. H.: The Pathology and Cyto-
genetics of Gonadal Agenesis, Amer. J. Obstet.
Gynec, 87:57S, 1963.
8. LiNDSTEN, J.: The Nature and Origin of
A^ril, 1966
31
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
X Chromosome Aberrations in Turner's Syn-
drome, Almquist and Wiksell, Stockholm, 1963.
9. LiNDSTEN, J., et ah: Source of the X
in XO Females: The Evidence of X7, Lancet,
7;558-559, 1963.
10. Mellinger, M.: Turner's Syndrome
with XO/XX Mosaicism, Henry Ford Hasp.
Med. Bull., i2.181-186, 1964.
11. MiKKELSEN, M., Froland, A., and
Ellebjerg, J.: XO/XX Mosaicism in a Pair
of Presumably Monozygotic Twins with Dif-
ferent Phenotypes, Cytogenetics, 2:86-98, 1963.
12. Miller, O. J.: The Sex Chromosome
Anomalies, Amer. J. Obstet. Gynec, 90.1078,
1964.
13. MOORHEAD, P. S., NOWELL, P. C, MeLL-
MAN, N. J., Battipps, D. M., and Hunger-
ford, D. A.: Chromosome Preparations of
Leukocytes Cultured from Human Peripheral
Blood, Exp. Cell. Res., 20;613, 1960.
14. Moszkowski, E. F., De Luca, L., and
Taubert, H. D.: Pure Gonadal Dysgenesis,
Obstet. & Gynec, 25.329, 1965.
15. Patau, K.: Chromosome Identification
and the Denver Report, Lancet, J. -93 3, 1961.
16. Penrose, L. S.: Fingerprints, Palms and
Chromosomes, Nature, 197:933, 1963.
17. Vaharu, T., Voorhess, M. L., Leibow,
L. G., Cara, J., Patton, R. G., and Gardner,
L. I.: XX/XO Mosaicism in a Girl, /. Pediat.,
67,-750-754, 1962.
18. Van Wijk, J. A. M., Blankenborg,
G. J., and Stolte, L. A. M.: XO/XX Mosaic-
ism and Mongolism in the Same Person, Lancet,
7.171, 1964.
19. Warren, J. C, Erkman, B., Cheatum,
S., and Holman, G.: Hilus Cell Adenoma in a
Dysgenetic Gonad with XX/XO Mosaicism,
Lancet, i.141-143, 1963.
32
Vol. 51, No. 2
poofe EctJtctosi
A University Is Born, By Margaret Byrnside,
M.D. Union. West Virginia, 1965.
■'Let us not lightly cast aside things that
belong to the past, for only with the past can
we weave the fabric of the future." Thus
wrote Anatole France, and we present his
statement in defense of the value of his-
torical considerations in these utilitarian
times.
The author's obstetrical background un-
doubtedly influenced her selection of the
title. She characterizes her work as a short
genealogical sketch of the University of
Maryland and not a definitive history; and
states her threefold purpose as follows:
"First — to show how the small unit of the
Medical College of Maryland, through
mergers and affiliations, finally, after more
than 100 years grew into a true University.
"Second — to bring the early fathers of
the institution into present day perspective,
to learn to know them, and to acclaim their
work.
"Third — to stimulate interest among the
present Faculties and Students of the Uni-
versity of Maryland in their heritage."
The first seven chapters depict the
"embryology" of the future university. The
engaging and detailed story continues to
evolve in the final eleven chapters, each
covering a decade through 1920; while the
epilogue brings the reader down to date with
a brief outline of significant events. Nine
appendices present facsimilies of the im-
portant legal acts which were basic in the
evolution of the university; and also de-
scriptions of the various institutions which
were combined to form the University of
Maryland. There are 215 text pages, and the
appendices occupy 80 pages. There is an
adequate combined index of subjects and
personal names. There are 31 unnumbered
pages of illustrations placed together near
the middle of the text. The binding is
attractive and the text type is clear.
The author's informal style facilitates easy
reading so that the reader becomes absorbed
in the narrative. For her fresh viewpoint,
and for the literary progeny born of the
painstaking travail of extensive personal
research, this reader is deeply grateful to the
author; and it is his belief that she, a most
loyal alumna of the University of Maryland
School of Medicine, has performed a real
service for her Alma Mater and for the
entire university. She has accomplished
her "triplet" purpose admirably. The book
is warmly recommended to all interested
in the University of Maryland.
John E. Savage, M.D.
Obstetrics. 13th Edition by J. P. Greenhill.
1245 pp. Illus. 'W. B. Saunders, Phila-
delphia. 1965. $22.00
The Thirteenth Edition of Obstetrics by
J. P. Greenhill, published by the Saunders
Company, is a comprehensive volume of
1245 pages. Included therein are 1296 il-
lustrations, 54 of which are in color. This
aspect of the book has to be classified as
magnificent, and is indeed one of the high-
lights.
Dr. Greenhill wisely selected 32 out-
standing world authorities to help prepare
special chapters of this edition. These men
have contributed excellent material in order
to modernize current trends and thoughts
in the specialty.
Noteworthy are the dynamic chapters on
erythroblastosis fetalis, pathology of labor,
human cytogenetics, fetal electrocardi-
ography, and obstetrical anesthesia.
April, 1966
33
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Two aspects of the book which do not
keep up with its general excellence are those
which pertain to the antibiotics and the
modern era of obstetrics and the teratogens
as they are known today.
As in the past, the bibliography is ex-
cellent, giving the reader easy access to
subject material. The language used
throughout the book is clear, concise, and
to the point.
In summary, it can be stated that this is
an all-inclusive book that encompasses the
spirit of the great Joseph B. DeLee, who
wrote the original edition. It is definitely
recommended for medical students.
Norman Levin
Diseases of the Newborn. 2nd Ed. By Alex-
ander J. Schaffer, M.D. and Milton
Markowitz, M.D. 1023 pp. Ulus. W. B.
Saunders Co., Philadelphia. 1965.
$20.00.
This second edition of Dr. Alexander J.
Schaffer's Diseases of the Newborn is
devoted to man's first 30 days of extra
uterine life. The book includes a section
on neonatal cardiology by Dr. Milton
Markowitz and a chapter on fluid and
electrolytes by Dr. Lawrence Finberg.
It is an excellent reference by a prac-
titioner for use by those interested in pedi-
atrics and general family medicine. It
is of particular value for pediatric interns
and residents as a basic source of infor-
mation and should prove to be an essential
part of their library.
The direct, flowing style is easy to read
and yet presents a massive amount of
material in a comparatively small space.
Topics are sub-titled in bold print as to
physical and laboratory findings, diagnostic
criteria, etiology, treatment, and prognosis.
Example cases are used generously and the
illustrations are better than average. In-
dexing is complete ,and can be used accur-
ately and quickly. Printing and binding
are the best.
The section dealing with cardiology is
outstanding in its content and practical usage
in diagnosis and treatment. Other chapters
of particular note include those on gastro-
intestinal and urinary tract disorders. The
appendices are unusual and valuable in
their presentation in outline form of proto-
cols for nursery care of both full term and
low birth weight infants; newborn drugs
and doses, resuscitation of the newborn,
and for management of the newborns with
suspected erythoblastosis.
Fluid balance by Dr. Finberg was un-
fortunately short and as a result was gen-
eralized. Future editions will no doubt find
this section expanded and will include more
information on the neonatal surgical patient
and his special problems.
Another topic to be anticipated is the
management of the caloric needs of the
newborn, be they normal or low birth
weight, stressed or stable.
In summary, this monograph is worth
the purchase price and will become more
valuable daily to those who buy it.
Donald E. Knickerbocker, M.D.
Chief Resident, In-Patient and
Nursery Service, University Hospital
34
Vol. 51, No. 2
MEDICAL SCHOOL SECTION
Dear Members of the Medical Alumni and Friends:
It is sometimes helpful and necessary to state in an oversimplified
form the facts as they pertain to medical education. We believe
they are as follows:
1. The four years of education in the medical school are primarily
focused on the student acquiring factual information and habits
of study.
2. The apphcation of the fund of knowledge in the basic medical
sciences to the patient and the recognition of normal and
abnormal findings in the patient and their management.
3. The reaUzation that achievement that justifies an M.D. degree
is only the base for the building of professional excellence.
4. That judgment and skill must be obtained through continuing
education, practice, and experience.
5. The choice of a field of medical practice is the right and re-
sponsibility of the individual involved.
6. The preparation for the field of practice takes place during the
internship and residency programs after the M.D. degree has
been awarded.
7. The medical school's responsibility in the individual's choice
of a field of medical practice is limited to acquainting the
individual with the opportimities available and making avail-
able advice if the student requests it.
Sincerely,
William S. Stone, M.D.
Dean
April, 1966
©r.
TiZichard R
TUayer
J-lppointed to fleurology Faculty
Dr. William S. Stone, Dean of the
School of Medicine, and Dr. Erland Nelson,
professor and head, department of neu-
rology, announce the appointment of Dr.
Richard F. Mayer as associate professor
of neurology effective November 1, 1965.
Dr. Mayer received his doctorate at the
University of Buffalo School of Medicine
in 1954. After medical internship at the
Boston City Hospital, he received his train-
ing in neurology at the Mayo Foundation,
Rochester, Minnesota, and the Massa-
chusetts General Hospital, Boston. From
1957 to 1958 he was assistant in research at
The National Hospital, Queen Square,
London, and during 1960-61, research and
teaching fellow in neurology at the Harvard
Neurological Unit, Boston City Hospital.
Dr. Mayer served with the Navy as neu-
rologist at the U. S. Naval Hospital, Chelsea,
Massachusetts in 1959-1960. He has been
a member of the faculty of the Harvard
Medical School from 1961 until the present
and has served as associate visiting physician
for neurology at the Boston City Hospital.
In addition, he has acted as director of the
Electroencephalographic Laboratory, Boston
City Hospital since 1964.
Dr. Mayer is well known for his signifi-
cant contributions in the areas of peripheral
nerve and muscle physiology and will con-
tinue an active program of clinical and ex-
perimental research in these areas while at
the University of Maryland.
Dr. Mayer has been a diplomate of the
American Board of Psychiatry and Neu-
rology since 1961 and is a fellow of the
American Academy of Neurology. His ap-
pointment brings to 7 the number of full-
time neurologists at the University of Mary-
land, making this newest department of the
School of Medicine one of the largest and
most versatile neurological groups in the
area.
Vol. 51, No. i
faculty
NOTES
Professor Figge Architect of
Unique Cadaver Law
Donation of bodies to the Anatomy Board
of Maryland is currently a well functioning
program according to Dr. Frank H. J.
Figge, chairman of the Anatomical Board
and professor of anatomy at the School of
Medicine. Some 800 or more individuals in
the State of Maryland have taken the neces-
sary steps according to a recently enacted
Maryland law which would make their bodies
available after death to one of the two
Medical Schools in the State of Maryland.
Under a Maryland law passed in 1960,
an individual by executing a donation form
can direct that his body be turned over
to the Anatomy Board. Donated bodies are
then given free transportation from the place
of death provided it is within the State.
Free embalming and free cremation are pro-
vided. Donors are supplied with a wallet
card giving directions for notifying the
Anatomy Board in the event of death.
Dr. Figge explained that at least 6,000
donations would be necessary in Maryland
in order to supply the two Medical Schools
with enough bodies for minimum dissection
requirements. In the past few years the total
number of unclaimed cadavers has declined
and Dr. Figge has indicated the necessity
for such remedial legislation in order to
insure the supply of dissection material for
oncoming classes of medical students.
Department of Medicine
Dr. Edmund G. Beacham, assistant pro-
fessor of medicine and chief of the tubercu-
losis division of the Baltimore City Hospitals,
was recently the recipient of the Governor's
award for promotion of the employment of
the handicapped. In addition to the State
award, Dr. Beacham received a citation for
meritorious service from the President's
committee on employment of the handi-
capped.
After receiving his medical training and
serving as a military surgeon, Dr. Beacham
became assistant chief and later chief of the
Tuberculosis Division of the Baltimore City
Hospitals. Since that time, he has served on
the staffs of both the Johns Hopkins and
the University of Maryland Schools of Medi-
Department of Pathology
Dr. Harlan I. Firminger, professor of
pathology and chairman of the department
of pathology at the School of Medicine, has
assumed the editorial responsibility for the
publication of the Fascid-es of the Atlas of
Tumor Pathology. Dr. Firminger serves
as editor for the Universities Associated for
Research and Education in Pathology.
Pathologists Present Important
Paper at Society for Experimental
Biology
Dr. Harlan I. Firminger, professor and
head of the Department of Pathology, and
Dr. Walter F. Oster, a recent chief resident
in the department, presented a paper en-
titled "Chloramphenicol Inhibition of Hepa-
tic Carcinogenesis in the Rat," on the oc-
casion of the annual meeting of the society
on April 14, 1966 at Atlantic City.
Doctors Firminger and Oster revealed that
chloramphenicol apparently by blocking pro-
tein synthesis was able to prevent induced
cancer in the liver of rats otherwise highly
susceptible in the absence of the chloram-
phenicol treatment.
Julius Friedenwald
Memorial Lecture
Dr. Nicholas C. Hightower, who is direc-
tor of clinical research at Scott and White
Clinic, Temple, Texas, spoke on "Esophageal
Functions in Health and Disease" on the oc-
casion of the annual lecture held Tuesday,
April 5th in Gordon Wilson Hall, University
Hospital. The lectureship was established in
1942 in honor of the late Dr. Julius Frieden-
wald, long a member of the medical school
faculty.
April, 1966
The Medical School Applicant Admission
Policies — A Faculty Problem
DIETRICH C. SMITH, Ph.D.
All medical schools are acutely aware
of the responsibilities they bear in selecting
those students who as physicians will be a
credit to their chosen profession and who
will be able to meet the increasing emotional
and intellectual demands of the medical
curriculum. In addition they are constantly
reminded of the increasing need for more
and better doctors. In Maryland for instance
it is estimated that by 1975 at least 240 new
physicians should be graduated that year
by the local medical schools to meet the
growing needs of the state for adequate
medical care. To understand what this
means it should be noted that in 1965 these
two schools graduated about 160 students,
80 short of the projected 10 year goal.
For the past 10 years the author has
served as chairman of the Committee on
Admissions of the University of Maryland
School of Medicine. During this time the
committee reviewed over 5,000 applications
from which they selected 500 students.
Inevitably this process could not go on with-
out certain guidelines and it is the purpose
of this article to try and explain by what
route the committee came to its decisions
during his period. It should be emphasized
at the beginning that the answers will not
always be clear cut, that there is no rigid
system, no computer-like techniques by
which its will was manifested. It should
also be stressed that what is said here ap-
plies to procedures used in the past and is
in no way intended to outline the official
policy, if such exists, in the future. The
author has no authority to set such a
policy, let alone define it. Time and circum-
stances change and selection procedures
* Professor of Physiology, Emeritus and
formerly Chairman, Committee on Admissions.
undergo the inevitable processes of evo-
lution.
First of all it must be clearly borne in
mind that no matter how estimable a young
man may be, no matter what his family
background or his dedication to a life
of service devoted to the benefit of his
fellow man, if he cannot pass the first two
years of the medical curriculum he will
never practice medicine. If a student falls
by the wayside the committee inevitably
feels that it has failed and in failing has
denied someone who is possibly a better
qualified person a place in the school.
The problem facing any admission com-
mittee is how to maintain good relations
with the general public and with the alumni
and to select from among the several hun-
dred applicants it must deal with each year
those who will best meet the needs of the
community for medical care and to satisfy
the faculty as to their competency to become
physicians. No doubt their ultimate de-
cisions seem capricious to many, especially
those who have been denied admission or
to a faculty member who feels that some
of those in his charge are not up to mastering
the material in his subject. The latter
frequently complain that the standards are
too low while disappointed alumni who
have sponsored their own children or the
children of their friends feel the commit-
tee has set up standards which are im-
possibly high and as a consequence deny
a place in the profession to many a meri-
torious, worthy and estimable young man.
It is therefore hoped that a discussion of
past admission procedures may shed some
light and understanding on how the process
of selection occurs. The decision to reject or
accept a student is based largely on his aca-
demic record, his Medical College Ad-
Vol. 51, No. 2
MEDICAL SCHOOL SECTION
mission test scores, his letters of recom-
mendation and the impression he makes on
interview. Each one of these criteria will
be discussed in some detail.
Academic Record. By this is meant the
record which the applicant has made during
the time spent in college, usually, a period
of four years but on occasion three and
rarely less. This record is the single most
important consideration which enters into
the final verdict. It is expressed quantitively
as the grade point average or more simply as
the GPA. At the Medical School of the Uni-
versity of Maryland during the period, 1955
to 1965, this was based on a scale of four,
where A = 4, B = 3, C = 2, D = 1 and
a condition or a failure = 0. The GPA
is calculated from the transcript or tran-
scripts which the applicant submits when
he applies. Since there are sometimes slight
differences between schools as to how they
calculate the GPA there may be a dis-
crepancy between the final average arrived
at by the applicant and by the medical
school. These differences however are minor
and need not concern us here. In making
these calculations the number of grade
points for each course are multiplied by the
number of semester hours or credits for
each course and the total divided by the
total number of credits or semester hours
accumulated by the applicant to date. Thus
a student who has obtained 90 credits and
280 grade points has a GPA of 3.11.
Potential applicants of course want to
know just what the committee expected in
the way of grade points. It was not easy
to answer this question as there is no
sharply defined cut-off point. The mean
GPA for the class entering the Medical
School of the University of Maryland in
September 1965 (Class of 1969) was 2.83
for residents and 2.93 for non-residents.
This figure will probably serve as good a
bench mark as any for what was expected
although of course it is obvious that if
the mean is approximately 3.0 there must
be a substantial number of accepted students
below this mean as well as a considerable
number above. A comparison between
science and non-science grades can also
be helpful. The applicant may have an
overall GPA of 2.8 but his science GPA
is considerably below this figure. If so he
is a poor risk for medical school since if
he is not capable of good work in under-
graduate courses in science it is extremely
doubtful if he can pass the science courses
of the medical curriculum where the stand-
ards are usually higher and the grading
more rigid. This is not necessarily true
of all colleges and no doubt this statement
will be disputed vigorously by some under-
graduate instructors.
Was his performance a consistent one?
Was his GPA approximately the same for
each of the three (or four) years of college
or did he start poorly and show progressive
and steady improvement? If so the overall
average might be a bit lower than the
committee would like but the applicant
has demonstrated his ability to do high
level work once he has set his mind to it.
Conversly did he start off well but gradually
slipped as he went on? If so, why? Was
it because he spent more and more time
in extra-curricular or social activities, be-
cause he had to take on outside work
to stay in school or because he was beset
that year with personal problems of an
emotional nature? Certainly the commit-
tee is better able to intei^jret the GPA
if it has knowledge of these circumstances.
The committee was also interested in the
undergraduate college attended. Some col-
leges are more selective than others in ad-
mitting students and so can maintain higher
standards of excellence. Experience over a
period of years gives some idea of where
a college stands in this respect. However
times change and academic standards are
on the rise everywhere. It is risky to as-
sume in this period of flux that what was
true of an institution 10 years ago is still
true today and therefore a certain measure
of restraint and caution should enter into
such judgments. Experience has shown that
it is not possible to set up a precise or
quantitative system of evaluation.
When all the ponderables as well as the
imponderables are taken into consideration
the GPA is still considered the best pre-
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
dictor for performance in medical school.
It is perhaps unfortunate in one way that
this is so as it serves to place a great deal
of emphasis on grades and focuses the
student's attention primarily on this aspect
of his studies rather than on a mastery of
the course contents themselves. Admittedly
there should be no conflict between these
two objectives but unfortunately students
oftentimes think there is in spite of he
protestations of faculty members to the con-
trary.
Medical College Admission Test. Virtu-
ally every applicant to any medical school
in the United States will take this test,
familiarly known as the MCAT or more
simply as the M-cat. It is given by a national
testing agency each fall and spring to those
students who expect to apply to some
medical school within the next few months.
Most medical schools prefer to have appli-
cants take the test during the spring of
their junior year. All applicants to Medical
School of the University of Maryland over
the past 10 years have been required to
take this test without exception and no
application was considered until the test
scores were in the committee's hands.
Furthermore no applicant could take the
test later than the October preceding the
year of desired admission.
By agreement among themselves medical
schools do not release the scores of appli-
cants although they are permitted to tell
the applicant whether or not he has met
the standards of his particular school and
how he stands in comparison to other appli-
cants to this school and to other schools.
The applicant may repeat the test one
year later or sooner if he can persuade
some medical school to give him permission
to do so. Substantial improvement on repe-
tition of the test seldom occurs.
The MCAT is a particularly useful tool
for admission committees since it gives an
objective measure by which all those who
took the test at that time can be compared
with one another. Since there are usually
about 8,000 students in each test group
the sampling is reasonably broad. Thus
applicant A from School X can be com-
pared with applicant B from School Y and
hopefully some measure of their relative
ability will emerge. From time to time the
testing agency compiles the mean scores
of all the students in any one college who
have taken the test over a stipulated period.
This compilation can be used as a yard-
stick to compare the performances of vari-
ous colleges and to compare the perform-
ance of a single student with his peers in
the same college. It therefore becomes a
useful check on the significance of the
GPA from any one school.
The MCAT is divided into four cate-
gories: verbal, quantitative, general infor-
mation, and science and the applicant is
scored separately in each category. The
scale ranges from a low of 200 to a high
of 800. Two-thirds of those taking the test
will score between 450 and 550 and ap-
proximately one-half will be above 500.
Obviously a score of over 550 places the
individual in a superior group for that
category while a score below 450 would be
a matter for concern especially if it is in
verbal or science.
Scores are not necessarily uniform in
all categories and different schools will use
the scores differently, some insisting on a
minimum score in all areas, or in the
science area alone or a combination of
science and quantitative. Others adopt a
less rigid attitude and are not too much
concerned about a low score in one area
providing other factors check out.
iTie correlation between MCAT scores,
especially in science, and the grades obtained
during the first two years of medical school
are quite good as is the correlation with the
scores on the National Board Examination,
Part I. The same cannot be said however
for the correlation between MCAT scores
and the grades in the clinical years or scores
on the National Board, Part II. However
again it must be borne in mind that a
student must pass the first two years of
medical school in order to have an oppor-
tunity to develop his clinical skills.
Objective multiple choice tests have been
under considerable fire from certain aca-
demic quarters and there are many who
Vol. 51, No. 2
MEniCAL SCHOOL SECTIOX
have doubts as to their validity and signifi-
cance. There are those who are equally
vehement in their defense. However there
is no doubt they serve a useful purpose in
the comparative evaluation of thousands of
students from diverse backgrounds and with
varying abilities. There seems to be little
doubt that such tests are here to stay and
that their use will spread rather than di-
minish. Rightly or wrongly under the selec-
tion systems \\ hich now operate for most col-
leges and professional schools these tests
play an important role. Furthermore a
student's success in professional school will
be determined to a large extent on how well
he handles such tests sifice he must take
them in one form or another as he ad-
vances through his professional education.
In evaluating an applicant his MCAT
scores are of course compared to his GPA.
and sometimes such comparison can be re-
vealing. How does one interpret a low
science score, say in the 400's, in an indi-
vidual who has a GPA of 3 or better in his
science subjects? Is he an over-achiever in
this area or are the standards at his school a
bit more rela.xed than elsewhere? Similarly
a low GPA and a high MCAT, say over
550 in all categories, demands some expla-
nation. Presumably such an individual did
not live up to his full academic potential.
Was it because he became too deply involved
in extra-curricular activities, was it because
he was indifferent to grades or was it be-
cause he had to work 20 or 30 hours a
week to stay in school? Would such an
individual realize his full potential in a
medical school where the academic environ-
ment might very well stimulate him to
greater efforts and where financial assistance
was more readily available. On the other
hand would his poor college record mean
he had not learned how to study, a handicap
that might very well prove fatal in medical
school.
The Interview. Probably no other phase
of the admission process is approached by
the applicant with so much trepidation and
anxiety as is the interview. Here is a face
to face confrontation with those whose de-
cision will be crucial in deciding his future
course in life. No wonder the candidate
looks upon the experience as an ordeal.
Interviewers do their best to put the appli-
cant at ease and usually succeed. Many
applicants will tell you that after the initial
tension had worn off they actually enjoyed
the experience. Tlie interviewer too de-
velops a certain humility as he comes to
realize more and more that it is difficult
to make a value judgement about a person
on the basis of a 20 minute conversation.
So why then go to all this trouble? Prob-
ably members of admission committees
spend more time on this phase of their
work than on any other. However it has
been aptly said that not many men will
select a wife or a secretary without first
speaking to her. Similarly admission
committees are reluctant to take any one
sight unseen.
Nevertheless the interview does serve a
useful purpose. Occasionally an interview
will reveal someone who is obviously unfitted
temperamentally or intellectually for medical
school. However it is probable that the
applicant benefits the most as it gives him
a chance to familiarize himself with the
school, to observe the classrooms and the
laboratories and to ask questions. It also
gives the interviewer a chance to obtain an
explanation for anything in the application
which he thinks needs explaining such as
why did he do poorly in the second semester
of his second year, why did he transfer
from one school to another, why was he
dropped from school and why did he volun-
tarily withdraw for two years. Sometimes
the answers to these questions can mean
the difference between a favorable and un-
favorable decision.
Probably in the course of a year between
four and five hundred applicants were inter-
viewed at the Medical School of the Uni-
versity of Maryland, at least 90% of them
on campus. In some schools, but not all,
interviewers will go to the applicant. This
is particularly true for a college which
will have a fairly large number of appli-
cants applying to the school in question.
The Medical School of the University of
Maryland, however, has not done this in
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
the past. However they have used inter-
viewers in distant places for applicants will
come from all over the United States and
it will happen that the geographical sepa-
ration is too great to be overcome. If such
an applicant looks promising he wUl be
asked to seek an interview with the nearest
local representative. Usually this regional
representative is an alumnus of the school
personally well known to some member of
the committee. These men can be very
helpful indeed and they put in many long
hours of work for which their only reward
is the heartfelt thanks of the committee plus
the knowledge that they have helped to
further the cause of medical education.
How should the candidate approach the
interview? Hopefully in as relaxed and
composed frame of mind as is possible
under the circumstances. A display of a
normal amount of anxiety however is not
necessarily detrimental and might even be
advantageous. An interviewer becomes
suspicious of a candidate who appears to
be too blase.
It is helpful if the applicant comes pre-
pared with a few question of his own. He
need not be afraid to reveal his ignorance
as no one expects him to be sophisticated
about medical education. It is perfectly
natural, in fact desirable, for him to want
to know something about the school's
curriculum, about its clinical facilities, what
is its drop-out rate, what provisions are
made for financial aid to students and many
other questions. In asking them the appli-
cant helps to establish a rapport between
himself and the interviewer which makes
everything run more smoothly.
Finally a word or two about personal
appearance. The applicant should be dressed
neatly in keeping with the standards of the
medical school he aspires to enter. His
dress should be such as to inspire respect and
confidence. Obviously he should be courte-
ous without being obsequious and cultivate
a manner that is in keeping with the tra-
ditions, the amenities and the dignity of
the medical profession.
Letters of Recommendation. Every com-
mittee expects an applicant to produce
letters of recommendation from those who
have had some academic contact with him
while in college. The more extensive this
contact the better. Letters from friends
of the family, the family doctor, the clergy,
the local banker are not encouraged and
are seldom given much weight if received.
Most liberal arts colleges have today a
premedical advisory committee with a chair-
man who usually serves as premedical ad-
visor for the college. This committee is
made up of those instructors who teach
premedical courses and therefore has a
high proportion of science teachers. How-
ever it is expected that the non-science areas
will also be represented. The premedical
advisor may or may not be a member
of the Dean's staff. If not it is usually
someone from the faculty who has had
considerable experience in this field. It is
his job to coordinate the activities of the
committee and usually to write the letters
based on the committee's recommendations.
In many instances the chairman of the pre-
medical advisory committee works closely
with the chairman of the admission com-
mittee of the medical school, especially if
that particular college annually has a large
number of applicants to the medical school
in question. Such a relationship can be
extremely helpful and often plays an im-
portant role in the admission process.
Where a special committee does not
exist then the applicant is forced to fall
back on individual letters from faculty mem-
bers who will speak for him. Such letters
are not always given the same weight as a
committee recommendation as they repre-
sent just one man's opinion and are not a
consensus of several experienced men.
Further the admission committee knows
full well that an applicant will select those
members of the faculty who in all prob-
ability will speak well of him. However the
committee does often learn to respect the
judgment of some one individual, par-
ticularly those who write frequently and are
jealous of their reputation for making im-
partial and objective judgments.
While the decision to admit or not to
admit an applicant is largely based on the
Vol. 51, No. 2
MEDICAL SCHOOL SECTION
GPA; MCAT, interviews and letters of
recommendation there are other factors
which play a part as well and in some indi-
vidual cases may be crucial. Perhaps the
most important of these is the residency of
the applicant. Since not all qualified appli-
cants can be accepted some sort of a screen-
ing process is inevitable if the committee is
to keep its workload at a reasonable level.
Since the Medical School of the University
of Maryland is a state supported school
preference is given to residents of the state
and every resident regardless of his qualifi-
cations is given careful and thorough con-
sideration. If he is qualified he is accepted
and during the past 10 years no Maryland
applicant has been rejected because there
was no place for him. This unfortunately
cannot be said of non-residents.
In the same category as residents are
placed the sons and daughters of alumni
of the university. While the term alumni
has never been strictly defined by the com-
mittee it certainly includes anyone who has
received a degree from any school or college
of the University of Maryland. This applies
doubly so to sons and daughters of alumni
of the medical school. While all "legacies"
receive special attention regardless of
residency they are expected to meet the
minimum qualifications before being ac-
cepted the same as anyone else.
So far as non-residents are concerned pre-
liminary screening cannot be avoided. Those
selected for further consideration and in-
vited to come in for an interview or to be
interviewed by a local representative are
those with promising MCAT scores and
high GPA's. The committee is also not
unaware of geography and a promising
applicant from an area which does not send
many applicants to the school will prob-
ably receive more serious consideration than
someone from a contiguous state. This is
not to say that candidates from these areas
are ruled out. Quite the contrary, because
of the fact that their number is large they
are usually well represented in the student
body.
The committee is also interested in having
as broad a representation from the colleges
as possible, especially those colleges which
have a high reputation in the academic com-
munity. Applicants who fall into this cate-
gory with a good academic record and high
MCAT scores are actively sought out by
several schools since they usually apply to
more than one. Competition is therefore
keen for these students and as a consequence
the ratio of those students who actually
matriculate at Maryland to those who are
sent offers is low. In such cases the de-
cision may turn on the prestige of the school,
the possibility of a scholarship or financial
aid and personal preferences in regard to
geographic location or a desire to work with
some distinguished member of the faculty.
In state supported schools there should
be no discrimination on the basis of sex,
religion, or race and such is most em-
phatically the case at Maryland. As to sex
there is a widespread belief that prejudice
exists towards women. This may or may
not be true in some schools but it is
definitely not the case at Maryland. Over
the years the percentage of women in the
student body has stayed constant at about
8%. Actually the number of offers sent
to women in relation to the number of
applicants is somewhat higher than it is
for men. This is probably due to the fact
the choice of medicine as a career is taken
far more seriously by women and their
motivation as a group somewhat stronger.
A woman does not enter medicine without
careful consideration of all aspects of the
situation and if she does so decide she
usually will make a more determined effort
to qualify.
As for race and religion, as mentioned
before, they play no part in the admission
process. The Medical School of the Uni-
versity of Maryland does not even inquire
into these factors.
The question often comes up concerning
the importance of extra-curricular activities.
It is certainly not expected that every suc-
cessful applicant will be a campus leader,
although it of course helps his chances if
he is and at the same time has a good
record. However being president of his
class, a member of the varsity football squad.
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
editor of the yearbook does not in itself
insure admission. The premedical curricu-
lum is a demanding one, loaded as it is with
science courses, and there is not much
time for outside activities. If too much in-
volvement in such efforts is jeopardizing
the student's academic standing he would be
well advised to cut down the load or elimi-
nate it entirely. By and large if an appli-
cant shows evidence of having normal social
relations with his peers and a reasonable
interest in the world around him most ad-
mission committees will be satisfied.
Finally the question of age. It is rare
indeed for an individual over 30 to be ac-
cepted and applicants from this group are
discouraged even though they be residents
of Maryland. As he advances beyond 30 his
chances dwindle rapidly and it is almost
unheard of to take anyone over 35. Ex-
perience has shown that older applicants
are not as good an academic risk as the
younger ones, although there are occasional
exceptions. In addition it is perfectly obvi-
ous that the number of years of effective
service to the community is statistically less
the older an applicant may be.
Hopefully this summary will help po-
tential applicants to medical school and their
parents to understand some of the problems
facing an admission committee and what
the applicant may expect. It is in this spirit
that this article is written. Certainly medi-
cine is looking for bright, alert, honest and
dedicated young people to enter its ranks.
Competition between professional schools
for such individuals is keen and medical
schools must make it clear they welcome
such applications. An applicant does not
necessarily have to be a Phi Beta Kappa
or to graduate cum laiide to be in the run-
ning. On the other hand it is also hoped
that aspiring applicants who obviously do
not measure up adopt a realistic attitude
about their chances and if they are rejected
to accept the decisions philosophically and
turn their efforts towards some other goal.
Vol. 51. No. 2
DEPARTMENT
OF
OBSTETRICS & GYNECOLOGY
Annual Report
Summary of Admissions, Discharges
and
Perinatal Mortality
University Hospital
January 1, 1964 through December 31, 1964
UNIVERSITY HOSPITAL
Baltimore, Maryland 21201
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Obstetrical Report for the University Hospital
For Period January 1, 1964 through December 31, 1964
I. SUMMARY
Total Discharges
Total Deliveries
Multiple Pregnancies
Twins (No. of sets)
By Cesarean section
Triplets (No. of sets)
By Cesarean section
Total Adult Deaths
Rates per 1000 live births
Total Live Births
Total Fetal Deaths
Rate per 1000 total births
Total Neonatal Deaths
Rate per 1000 total births
Total Perinatal Mortality
Rate per 1000 total births
Perinatal Mortality (1000 grams & over)
Rate per 1000 total births
932
870
5
0.00
858
12
13.79
18
20.69
30
34.48
24
27.78
2099
1972
27
1
0.00
1928
44
22.31
45
22.82
89
45.13
57
29.41
3031
2842
32
1
0.00
2786
56
19.70
63
22.17
119
41.87
81
28.91
II. TOTAL DISCHARGES BY TYPE OF DELIVERY
Abortion*, completion of
Abortion, spontaneous
Abortion, therapeutic
Ectopic pregnancy, early
Ectopic pregnancy, late
Full Term, spontaneous delivery. .
Full Term, operative delivery . . . .
Prematuret, spontaneous delivery
Premature, operative delivery . . . .
ImmatureJ, spontaneous delivery .
Immature, operative delivery
Postpartum admission
Discharged undelivered
Not pregnant
Died undelivered
Total Discharges
Percentage
3
341
433
52
38
4
2
59
932
30.7
1
12
2
1029
591
193
125
22
12
112
2099
69.3
1
15
2
1370
1024
245
163
26
14
171
3031
100.0
* An abortion is any fetus or infant weighing between 0-499 gm.
t A premature is any fetus or infant weighing between 1000-2499 gm.
X An immature is any fetus or infant weighing between 500-999 gm.
Vol. 51, No. 2
DEPARTMEST OF OBSTETRICS AND CVS ECOLOGY— AS SU AL REPORT
m. TOTAL DISCHARGES BY REASON FOR ADMISSION
True labor
Suspected labor
Elective induction
Indicated induction
Postpartum admission
Ectopic pregnancy
Elective section
Abortion, threatened
Abortion, completion of . . .
Abortion, therapeutic
Obstetrical disease
Medical disease
Surgical disease
Mole and Chorio-carcinoma
Not pregnant
Special study
Total
681
30
37
21
13
3
147
1567
27
3
20
40
15
422
2
3
2248
57
40
41
53
18
569
2
3
2099
3031
IV. SERVICE STATUS
Race
Private
Ward
Total
No.
%
No.
%
No.
%
White
489
443
52.5
47.5
2041
58
97.2
2.8
2530
501
83.5
Xon-White
16.5
Total
932
100.0
2099
100.0
3031
100.0
v.— A AGE AND PARITY— TOTAL PATIENTS DELIVERED
White Discharges
PARITY
Total
Perinatal
Mortality
1
2
3
4
5
6
7
8
9
10 &
Over
Un-
known
No.
%
Under 15 . . .
15-19
20-24
25-29
30-34
35-39
40-14
4.5-49
50 and over.
4
117
77
27
5
3
25
97
47
17
6
2
12
76
62
23
8
3
4
30
33
25
9
4
16
24
13
7
2
7
20
7
11
3
10
8
3
2
3
4
4
1
1
1
2
1
1
2
1
4
158
303
227
106
55
17
0(0)
5(1)
12(3)
6(1)
3(1)
2(0)
2(0)
0(0)
0(0)
0.0
3.2
4.0
2.6
2.8
3.6
11.8
0.0
0.0
Total
233
194
184
105
62
48
23
11
3
3
4
870
30(6)
3.4
Perinatal
Mortality
No.
9(2)
3.9
6(1)
3.1
4(1)
2.2
3(0)
2.9
4(0)
6.5
1(1)
2.1
1(1)
4.3
1(0)
9.1
0(0)
0.0
0(0)
0.0
1(0)
25.0
0(0)
0.0
30(6)
3.4
Per Cent . . .
The numbers in ( ) indicate immature deaths.
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
v.— B AGE AND PARITY— TOTAL PATIENTS DELIVERED
Non-White Discharges
PARITY
Total
Perinatal
Mortality
AGE
1
2
3
4
5
6
7
8
9
10 &
Over
Un-
known
No.
%
Under 15
22
282
103
14
4
5
1
169
140
33
17
9
50
169
55
27
14
2
15
87
53
33
13
3
58
55
34
15
8
36
76
34
18
4
15
42
25
21
5
1
4
27
30
20
3
3
8
19
11
6
3
17
7
3
1
3
13
17
10
22
519
615
369
253
150
42
2
0(0)
23(10)
24(10)
14(4)
14(6)
12(2)
2(0)
0(0)
0(0)
15-19
20-24
25-29
4.4
3.9
3 8
30-34
35-39
5.5
8
40^4
4 8
45^9
50 and over
0.0
0.0
Total
431
368
317
201
173
168
109
84
47
31
43
1972
89(32)
4.5
Perinatal
Mortality
No
19(10)
4.4
14(5)
3.8
16(3)
5.0
13(7)
6.5
5(2)
2.9
8(1)
4.8
2(1)
1.8
2(0)
2.4
3(0)
6.4
3(1)
9.7
4(2)
9.3
0(0)
0.0
89(32)
4.5
Per Cent
VI.— A PRENATAL CARE— TOTAL PATIENTS DELIVERED
White
Non-White
Total
Perinatal Mortality
Number of Prenatal Visits
No.
%
No.
%
No.
%
No.
%
1-3
4r^
7-9
65
73
132
189
105
65
107
134
7.5
8.4
15.2
21.7
12.1
7.5
12.3
15.4
158
307
521
501
273
94
61
57
8.0
15.6
26.4
25.4
13.8
4.8
3.1
2.9
223
380
653
690
378
159
168
191
7.8
13.4
23.0
24.3
13.3
5.6
5.9
6.7
26(13)
26(13)
29(6)
11(0)
8(0)
4(0)
6(2)
9(4)
11.7
6.8
4.4
1.6
10-12
2.1
13 or more
Elsewhere
2.5
3.6
4.7
Total
870
100.0
1972
100.0
2842
100.0
119(38)
4.2
VI.— B TIME OF FIRST VISIT
White
Non-White
Total
Perinatal Mortality
No.
%
No.
%
No.
%
No.
%
13 weeks or earlier
65
350
165
118
7.5
40.2
19.0
13.6
156
906
639
52
7.9
45.9
32.4
2.6
221
1256
804
170
7.8
44.2
28.3
6.0
8(1)
44(9)
26(9)
9(4)
3.6
3.5
28 weeks or later
3.2
5.3
Total
698
80.2
1753
88.9
2451
86.2
87(23)
3.5
Vol. 51, No. 2
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
Vn. PRESENTATIONS— TOTAL INFANTS
White
Non-White
Total
Perinatal Mortality
Presentation
No.
%
No.
%
No.
%
No.
%
831
29
2
3
4
1
95.5
3.3
0.2
0.3
0.0
0.5
0.1
1876
72
11
2
2
9
95.1
3.7
0.6
0.1
0.1
0.5
0.0
2707
101
13
5
2
13
1
95.2
3.6
0.5
0.2
0.1
0.5
0.0
85(23)
25(12)
3(1)
1(0)
0(0)
4(2)
1(0)
3.1
24.8
23.1
20.0
Compound
0.0
30.8
Unknown
100.0
Total
870
100.0
1972
100.0
2842
100.0
119(38)
4.2
Twins
Triplets
10
1.1
0.0
54
2.7
0.0
64
2.3
0.0
8(2)
0(0)
12.5
0.0
*Breech Perinatal Mortality
500-999 gm
1000-1499 gm...
1500-1999 gm...
2000-2499 gm. . .
2500 gm. & over .
Total
1
3.4
12
16.7
13
12.9
3
10.3
9
12.5
12
11.9
0.0
13
18.1
13
12.9
4
13.8
7
9.7
11
10.9
21
72.4
31
43.1
52
51.5
29
100.0
72
100.0
101
100.0
92.3
58.3
7.7
9.1
7.7
25
24.8
Mortality 1000 grams and over — 12.9%.
Vm. METHOD OF DELIVERY— TOTAL INFANTS
Perinatal
Mortality
Vagina! deliveries
1. Total forceps deliveries
Low forceps, elective
Low forceps, indicated
Mid forceps, elective
Mid forceps, indicated
High forceps
Vacuum extractor, elective.. . .
Vacuum extractor, indicated. .
Failed forceps /extractor
2. Breech
Spontaneous
Assisted
Extraction
Decomposition & Extraction. ,
3. Other operations
Version and extraction (single)
Version and extraction
(second twin)
Manual rotation, head only. . .
Rotation of shoulders
Destructive operations
Conversion only
4. Spontaneous
Abdominal deliveries
1. Cesarean section
2. Rupture of uterus
3. Advanced ectopic pregnancy. .
400
306
93
1
25
2
6
16
1
2
1
1
395
48
47
1
46.0
551
35.2
417
0.0
10.7
134
0.1
0.0
0.0
0.0
0.0
2
2.9
54
0.2
12
0.7
13
1.8
27
0.1
2
0.2
6
0.0
1
0.0
4
0.1
1
0.0
0.1
45.4
1232
5.5
129
5.4
128
0.1
0.0
1
27.9
21.1
0,0
6.S
0.0
0.0
0.0
0.0
0.1
2.7
0.6
0.7
1.4
0.1
0.3
0.1
0.2
0.1
0.0
0.0
0.0
62.5
6.5
6.5
0.0
0.1
951
723
227
1
2
79
14
19
43
3
8
1
4
2
1
1627
177
175
1
1
33.5
25.4
0.0
8.0
0.0
0.0
0.0
0.0
0.1
2.8
0.5
0.7
1.5
0.1
0.3
0.0
0.1
0.1
0.0
0.0
0.0
57.2
6.2
6.2
0.0
0.0
16(2
12(1
0(0
4(1
0(0
0(0
0(0
0(0
0(0
19(8
4(2
5(3
10(3
0(0
2(2
1(1
1(1
0(0
0(0
0(0
0(0
61(22
21(4
19(3
1(0
1(1
1.7
1.7
0.0
1.8
0.0
0.0
0.0
0.0
0.0
24.1
28.6
26.3
23.3
0.0
25.0
100.0
25.0
0.0
0.0
0.0
0.0
3.7
11.9
10.9
100.0
100.0
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
EX. ANCILLARY OPERATIVE PROCEDURES FOR LABOR AND DELIVERY
Perinatal
Mortality
A. Induction of labor
Oxytocic
Rupture of membranes
Rupture of membranes and
oxytocic
Stripping of membranes
Stripping of membranes and
oxytocic
Other
Total Inductions
(Perinatal mortality over 1000
grams 0.0%)
Total Elective Inductions.. .
B. Miscellaneous
Decompression of hydrocephalus.
Forceps to after-coming head . . .
Manual removal of placenta,
elective
Manual removal of placenta,
indicated
Oxytocic stimulation of labor . . .
(Perinatal mortality over 1000
grams 0.0%.)
Elective Oxytocic Stimulation
Tran8fusion(s)
Exploration of Uterus
C. Episiotomies and lacerations
Median
3rd degree lacerations
4th degree lacerations
Mediolateral
3rd degree lacerations
4th degree lacerations
Total Episiotomies
3rd degree laceration spontaneous,
repair of
4th degree laceration spontaneous,
repair of
Cervical laceration, repair of. .
Vaginal laceration, repair of . .
D. Other procedures
Appendectomy, incidental ....
Other gyn. oper
Other surg. oper
Hysterorrhaphy
32
20
30
9
1
567
9
20
55
1
7.8
0.0
0.0
0.0
0.0
0.0
7.8
0.0
1.1
0.6
1.5
3.4
1.0
0.1
65.2
1.0
2.3
6.3
0.1
0.0
40
39
6
919
20
25
50
1
2.0
0.0
0.0
0.0
0.0
0.0
2.0
0.0
0.2
0.9
1.0
2.0
2.0
0.3
46.6
1.0
1.3
2.5
0.1
0.0
107
107
35
33
1486
29
45
105
2
3.8
0.0
0.0
0.0
0.0
0.0
3.8
0.0
0.5
0.8
1.2
2.5
1.7
0.2
52.3
1.0
1.6
3.7
0.1
0.0
4(1)
0(0)
0(0)
0(0)
0(0)
0(0)
4(1)
0(0)
0(0)
3(0)
1(1)
8(5)
3.7
0.0
0.0
0.0
0.0
0.0
3.7
0.0
0.0
21.4
3.0
11.4
74.9
51.5
1667
58.7
0.0
0.1
0.3
0.6
0.1
0.9
0.1
0.2
0.7
0.7
0.1
0.0
0.9
0.0
0.1
0.5
0.6
0.2
0.0
0.9
0.0
0(0)
0(0)
3(2)
0(0)
0.0
0.0
11.5
0.0
Vol. 51, No. 2
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
X. PUERPERAL MORBIDITY
White
Non-White
Total
No.
%
No.
%
No.
%
49
47
5.6
5.4
149
212
7.6
10.8
198
259
7.0
9.1
Total
96
n.o
361
18.3
457
16.1
Infection
Endometritis
Mastitis
18
1
1
13
2.1
0.0
0.1
0.1
0.0
1.5
119
8
5
4
1
65
6.0
0.4
0.3
0.2
0.1
3.3
137
8
6
5
1
78
4.8
0.3
0.2
0.2
Peritonitis
0.0
2.7
Other Complications
Respiratory Disease
Abdominal Wound Dehiscience
Postspinal SjTnptoms
5
3
1
0.6
0.3
0.1
14
1
2
0.7
0.1
0.1
19
4
3
0.7
0.1
0.1
XI. COMPLICATIONS
Perinatal
Mortality
A. Antepartum hemorrhage
Placenta previa
Abruptio placentae
Rupture of uterus
Traumatic
Previous section, severe . . .
Previous section, incidental
Other causes
Total
B. Postpartum hemorrhage
Early
Late
Hematomata
Total
C. Anemia
Less than 5 gm
5.0- 5.9 gm
6.0- 6.9 gm
7.0- 7.9 gm
8.0- 8.9 gm
9.0- 9.9 gm
10.0-10.9 gm
11 gm. and over
Unknown
Total
0.7
1.4
0.1
0.0
0.1
0.0
0.0
0.6
1.9
0.0
0.0
0.0
0.0
0.2
0.6
1.7
0.0
0.0
0.0
0.0
0.1
2(2)
21(6)
0(0)
0(0)
1(0)
0(0)
1(1)
11.1
42.9
0.0
0.0
100.0
0.0
33.3
2.5
25(9)
35.2
1.8
0.0
0.0
2.9
0.0
0.0
2.6
0.0
0.0
1.8
58
2.6
4
4
20
53
764
25
0.0
0.0
0.0
0.5
0.5
2.3
6.1
87.8
2.9
1
5
8
134
350
1442
32
0.0
0.1
0.0
0.3
0.4
6.8
17.7
73.1
1.6
1
9
12
154
403
2206
57
0.0
0.0
0.0
0.3
0.4
5.4
14.2
77.6
2.0
0(0)
0(0)
0(0)
2(2)
3(1)
8(1)
18(5)
83(25)
5(4)
0.0
0.0
0.0
22.2
25.0
5.2
4.5
3.8
870
100.0
1972
100.0
2842
100.0
119(38)
4.2
April. 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
XI. COMPLICATIONS (Cont.)
White
Non-White
Total
Perinatal
Mortality
No.
%
No.
%
No.
%
No.
%
D. Toxemia
Pre-eclampsia — mild
Pre-eclampsia — severe
Eclampsia — antepartum
Eclampsia — intrapartum
Eclampsia — postpartum
27
2
3.1
0.2
0.0
0.0
0.0
73
5
2
2
3.7
0.3
0.1
0.0
0.1
100
7
2
2
3.5
0.2
0.1
0.0
0.1
7(0)
0(0)
0(0)
0(0)
0(0)
7.0
0.0
0.0
0.0
0.0
29
3.3
82
4.2
111
3.9
7(0)
6.3
Chronic hyper, with toxemia
Chronic hyper, without tox
16
0.0
1.8
11
120
0.6
6,1
11
136
0.4
4.8
1(0)
9(2)
9.1
6.6
16
1.8
131
6.6
147
5.2
10(2)
6 8
1
0.1
0.0
1
0.0
0(0)
Total Toxemia
46
5.3
213
10.8
259
9.1
17(2)
6.6
E. Medical complications
Heart disease
2
1
1
1
2
114
3
6
5
1
2
8
21
1
3
4
1
1
0.2
0.1
0.1
0.0
0.0
0.1
0.0
0.0
0.2
13.1
0.3
0.7
0.0
0.6
0.1
0.2
0.9
2.4
0.1
0.3
0.5
0.0
0.1
0.0
0.1
0.0
4
3
1
1
1
3
124
2
8
5
6
5
1
29
39
2
18
19
4
0.3
0.2
0.1
0.0
0.1
0.1
0.0
0.0
0.2
6.3
0.1
0.4
0.3
0.3
0.3
0.1
1.5
2.0
0.1
0.9
1.0
0.0
0.2
0.0
0.0
0.0
6
4
2
1
2
5
238
5
14
5
11
6
3
37
60
3
21
23
5
1
0.2
0.1
0.1
0.0
0.0
0.1
0.0
0.0
0.1
8.4
0.2
0.5
0.2
0.4
0.2
0.1
1.3
2.1
0.1
0.7
0.8
0.2
0.0
0.0
0.0
0(0)
0(0)
0(0)
0(0)
0(0)
0(0)
0(0)
0(0)
0(0)
10(5)
0(0)
1(0)
1(0)
6(2)
0(0)
3(0)
11(5)
1(1)
0(0)
2(2)
0(0)
0(0)
0(0)
0(0)
0(0)
0(0)
0.0
Failure
Tuberculosis, pulmonary
0.0
0.0
0.0
Other pulmonary disease
0.0
0.0
0.0
4.2
Rubella
0.0
7.1
Abnormal glucose tol. test
F. Cord pathology
Prolapse — Vaginal deliveries
Prolapse — Abdominal deliveries . .
Other
20.0
54.5
0.0
100.0
29.7
1.7
I. Labor over 20 hours —
method of delivery
0.0
9.5
Low forceps, elective
Low forceps, indicated
0.0
0.0
0.0
Mid forceps, indicated
0.0
0.0
Other
0.0
Total
10
1.1
43
2.2
53
1.9
2(2)
3.8
2
9
0.2
1.0
6
56
0.3
2.8
8
65
0.3
2.3
1(0)
1(0)
12.5
1.5
Vol. 51, No. 2
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
XII. ABDOMINAL OPERATIONS
White
Non-White
Total
Perinatal
Mortality
Prim.
Repeat
Prim.
Repeat
Prim.
Repeat
Prim.
Repeat
A. Cesarean sections
22
5
3
1
4
12
47
5
15
2
69
27
16
6
10
69
10
18
3
31
28
6
10
11.6
10.0
27.8
33.3
0.0
0.0
6.5
Low cervical and sterilization ....
0.0
16.7
Classical and sterilization
E.xtraperitoneal
10.0
0.0
0.0
Total Sections
31
16
59
100
75
15.0
5.3
Indications
1. Pelvic contractions and
mechanical dystocia
3
6
3
1
2
4
8
5
14
4
3
1
6
23
11
11
17
4
3
2
8
27
0.0
0.0
0.0
0.0
0.0
0.0
50.0
0.0
0.0
0.0
50.0
3.7
0.0
Tumor blocking birth canal
0.0
Total
12
4
27
23
39
27
3 7
2. Previous uterine surgery
Previous cesarean section
Previous myomectomy
11
29
40
0.0
0.0
0.0
2.5
0.0
0.0
Total
11
29
40
3
3
0.0
2 5
3. Hemorrhage
5
3
1
8
10
2
3
13
13
25.0
62.5
0.0
Placenta previa
Other
100.0
0.0
Total
8
1
18
5
26
6
100.0
100
4. Toxemia
1
2
1
2
0.0
0.0
0.0
0.0
Eclampsia
Chronic hypertension
0.0
Total
3
3
0.0
0.0
5. Intercurrent diseases
2
1
3
33.3
6. Miscellaneous Total
3
1
2
3
3
1
2
2
1
1
6
4
1
2
4
1
1
0.0
0.0
0.0
0.0
0.0
50.0
Prolapsed cord
0.0
0.0
0.0
Other
0.0
B. Cesarean hysterectomy
D. Laparotomies
1
1
1
1
Rupture of uterus
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
XIII. DELIVERIES (INFANTS) WITH PREVIOUS SECTION
Repeat section
Vaginal deliveries
Spontaneous
Low forceps, elective
Low forceps, indicated
Mid forceps, elective
Breech, spontaneous
Breech, extraction
Breech, decomposition & extraction
Other (specify)
Total
1.8
0.2
0.1
0.0
0.0
0.0
0.0
0.0
0.1
0.3
0.1
0.0
0.1
0.0
0.0
0.0
0.0
0.2
0.1
0.0
0.0
0.0
0.0
0.0
0.0
4(0)
0(0)
1(0)
0(0)
0(0)
0(0)
0(0)
0(0)
1(0)
5.3
0.0
33.3
0.0
0.0
0.0
0.0
0.0
100.0
2.3
67
3.4
6(0)
XIV. THERAPEUTIC ABORTIONS
White
Non-White
Total
No.
No.
No.
Indications :
1
1
XV. STERILIZATION
Type of Operation
Tubal, puerperium
Tubal, not pregnant
Accompanying cesarean section
Accompanying therapeutic abortion.
Hysterectomy, with cesarean section
Hysterectomy, puerperal, steril
X-ray
Total
Indications for Sterilization
Multiple cesarean sections
Multiparity
Other
Total
21
7
28
18
33
51
1
1
Vol. 51, No. 2
DEPARTMEXT OF OBSTETRICS A.\'D GYXECOLOGY— ANNUAL REPORT
XVI ADULT DEATHS
Total Births
Maternal deaths
Kate per 1000 births
Total Registered Birtlis
jSIaternal deaths (registered patients)
Rate per 1000 registered births
2842
0.00
2451
0.00
XVn. MALFORMATIONS
Perinatal
Mortality
Club Foot
Polydaetylism
Undescended Testes. . .
Hypospadias
Mouth
CXS System
Cardiovascular System
Other
Total
3
3
6
2(0)
1
8
9
2(0)
1
3
4
1(0)
1
5
6
0(0)
1
1
0(0)
8
8
16
7(1)
8
15
23
7(1)
3
9
12
3(0)
20
45
65
16(2)
33.3
22.2
25.0
0.0
0.0
43.8
30.4
25.0
24.6
XVm. CAUSE OF PERINATAL DEATH
White
Non-White
Total
5
1
8
6
1
8
1
3
2
29
20
3
3
2
27
8
3
37
26
3
3
3
35
Other
1
Total
30
89
119
XIX. INFANTS DELIVERED
A. Total Live Births According to Weight and Condition at Discharge
White
Non-White
Total
Live
Births
Died
%
Live
Births
Died
%
Live
Births
Died
%
500- 999
5
6
14
66
767
5
4
9
100.0
66.7
0.0
0.0
1.2
15
29
82
195
1607
13
11
6
7
8
86.7
37.9
7.3
3.6
0.5
20
35
96
261
2374
18
15
6
7
17
90
1000-1499
42 9
1500-1999
6 3
2000-2499
2500 and over
2.7
0.7
Total
858
18
2.1
1928
45
2.3
2786
63
2.3
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
B. Total Stillbirths According to Weight
Birth Weight Grams
White
Non-White
Total
Total
Births
Still-
births
%
Total
Births
Still-
births
%
Total
Births
Still-
births
%
600- 999
6
8
15
67
774
1
2
1
1
7
16.7
25.0
6.7
1.5
0.9
34
33
89
196
1620
19
4
7
1
13
55.9
12.1
7.9
0.5
0.8
40
41
104
263
2394
20
6
8
2
20
50
1000-1499
1500-1999
2000-2499
14.6
7.7
8
2500 and over
0.8
Total
870
12
1.4
1972
44
2.2
2842
56
2
C. Total Perinatal Deaths According to Weight
Birth Weight Grams
White
Non-White
Total
Total
Births
Peri-
natal
Deaths
%
Total
Births
Peri-
natal
Deaths
%
Total
Births
Peri-
natal
Deaths
%
500- 999 ...
6
8
15
67
774
6
6
1
1
16
100.0
75.0
6.7
1.5
2.1
34
33
89
196
1620
32
15
13
8
21
94.1
45.5
14.6
4.1
1.3
40
41
104
263
2394
38
21
14
9
37
95.0
1000-1499
1500-1999
2000-2499
2500 and over
51.2
13.5
3.4
1.5
Total
870
30
3.4
1972
89
4.5
2842
119
4.2
Vol 51, No. '£
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
GYNECOLOGIC REPORT
I. DISCHARGES PER PATIENT
1 2
3
4
5
6
Total
Number of patients
809
83
13
3
1
1
910
U. GENERAL DISCHARGE TYPE
Number of discharges
A. Gynecologic benign
1. Surgical
a. Minor, single
b. Minor, multiple. . .
c. Major, single
d. Major, multiple. . .
2. Non-operative
3. For diagnosis only. . .
B. Gynecologic cancer
C. Pregnancy complications
D. Miscellaneous
558
295
192
56
133
3
53
50
165
479
285
155
26
129
19
111
94
81
19
1037
580
347
82
262
3
72
161
259
169
29
in. DEATHS
A. Operative
B. Non-operative
C. Diagnosis only
D. Cancer
E. Pregnancy complications .
F. Miscellaneous
Total.
IV. TRANSFERS
Number .
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
V. PRIMARY AND SECONDARY GYNECOLOGIC DIAGNOSIS
A. Vulva
D. Uterus
Diagnosis
Primary
Secondary
Abscess, Bartholin's
gland
Cyst, Bartholin's gland.
Hymen, Imperforate . . .
Papilloma of Vulva ....
Sebaceous Cyst, Vulva. .
Endometriosis
Other
9
1
1
1
1
2
1
1
Total
15
2
B. Vagina
Cyst, Gartner's duct .
Cystocele
Endometriosis
Enterocele
Prolapse
Rectoeele
Vaginitis, fungus
Stricture
Urethrocele
Incomplete tear
Syphilis
Hematoma
Fistula, Vesicovaginal
from trauma
Total
C. Cervix
Cervicitis, acute
Cervicitis, chronic . . .
Cyst, Nabothian
Erosion
Laceration
Polyp
Prolapse, stump
Basal cell hyperplasia
Stenosis
Endometriosis
Total
7
162
13
2
1
3
1
1
Adenomyosis
Anomaly
Endometritis, acute. . .
Endometritis, chronic. .
Endometrium, atrophic
Endometrium,
hyperplasia
Endometrium,
proliferative
Endometrium,
secretory
Fibromyomata
Polyp, endometrial. . . .
Prolapse
Retroversion
Hyperplasia
Subinvolution of
placental site
Total
Primary Secondary
Diagnosis
Primary
Secondary
Abscess, tubo-ovarian
(intact)
Abscess, tubo-ovarian
8
4
8
U
10
1
1
1
Endometriosis
Hydrosalpinx
Salpingitis, acute
Salpingitis, chronic
Perisalpingitis, acute . . .
Perisalpingitis, chronic.
Other
1
7
6
28
2
Total
46
45
Vol. 51. No. 2
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
V. PRIMARY AND SECONDARY GYNECOLOGIC DIAGNOSIS (Conl.)
F. Ovary G. Other Gynecologic Diagnosis
Diagnosis
Primary Secondary
Brenner tumor
Cyst, corpus luteum.. . .
Cyst, dermoid
Cyst, follicular
Cyst, parovarian
Cyst, simple
Cyst, undetermined ....
Cystadenoma,
pseudomucinous
Cystadenoma, serous. . .
Endometritis
Fibroma
Oophoritis, chronic
Other
Ovaries, poly cystic
(S. L. Diseases)
7
6
1
2
2
2
3
1
3
4
1
2
10
2
5
1
1
1
3
2
1
1
Total
32
29
Diagnosi
Abscess, pelvic
Amenorrhea,
hypothalamic
Bleeding, functional
uterine
Bleeding,
postmenopausal . . .
Cellulitis, pelvic
Endometriosis, pelvic
Infertility
Mass, adnexal
Peritonitis, pelvic. . . .
Smear, Pap.
Inconclusive
Sterility
Sterilization
Pelvic, congestive. . . .
Post hysterectomy
Bleeding
Smear, Pap. Positive.
Others
Total
VI. CANCER (Based on Patients)
A. Vulva
30
Irradiated
Operations
Irradiated
and Operated
Adenocarcinoma.
Epidermoid
2. Complications
Carcinoma metastatic to lymph of
groin
B. Vagina
1. Diagnosis
Number of
Patients
Irradiated
Operations Irradiated Medical
[and Operated!
Epidermoid
Adenocarcinoma
2
1
1
1
1
C. Cervix
1. Diagnosis
Number of i„adiated
Patients
Operations
Irradiated
and Operated
Medical
Adenocarcinoma
Carcinoma in situ
Squamous cell
2
14
117
7
70
1
4
28
1
3
19
Total 133
77
33
23
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
VI. CANCER (Based on Patients) (Cont.)
C. Cervix (Cont.)
2. Complications
Cellulitis, pelvic
Fistula, rectovaginal (radium). . . .
Lymph nodes in pelvis, metastatic
Lymph nodes out of pelvis,
metastatic
D. Uterus
1. Diagnosis
Number of
Patients
Irradiated
Operations
Irradiated
and Operated
Medical
Adenocarcinoma
17
3
1
2
3
2
10
2
1
Sarcoma
1
Total
21
2
5
10
4
2. Complications
Number
Lymph nodes in pelvis, metastatic . .
Lymph nodes out of pelvis,
metastatic
3
1
E. Tubes
1. Diagnosis
Number of
Patients
Carcinoma
F. Ovary
1. Diagnosis
Number of
Patients
Irradiated
Operations
Irradiated
and Operated
Medical
6
1
8
1
4
2
1
1
3
4
Cystadenocarcinoma,
pseudomucinous
Cystadenocarcinoma, serous
Granulosa cell
1
6
1
1
Total
20
3
4
13
2. Complications
Number
4
2
4
Lymph nodes in pelvis, metastatic . .
Lymph nodes out of pelvis,
metastatic
Vol. 51. No. 2
DEPARTMEXT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
VI. CANCER (Based on Patients^ (Cont.)
G. Unknown Source
VII. PREGNANCY COMPLICATIONS
Diagnosis
Number of
Patienta
Abortion, incomplete
Hemorrhage, postpartum, late
98
3
1
4
30
Pregnancy, tubal ruptured
Pregnancy, tubal unruptured
Secundines, retained
Subinvolution of placental site
25
3
1
4
Total
169
VIII. OTHER SYSTEMS— DIAGNOSIS
A. Rectum D. Ureters
Diagnosis
Primary
Secondary
Other
1
Total
1
Diagnosis
Primary
Secondary
2
2
1
Total
2
3
E. Kidneys
Diagnosis
Primary
Secondary
Caruncle
Diverticulum
Polvp ....
1
1
1
2
6
3
2
Urethritis, chronic
Incontinence
Stricture
1
4
2
Others
Total
16
7
C. Bladder
Diagnosis
Primary
Secondary
Carcinoma, metastatic. .
Cystitis, acute
Cystitis, chronic
Other . . .
3
3
2
5
1
Total
6
8
Diagnosis
Primary
Secondary
Hydronephrosis
Other
Pyelonephritis, acute. . .
Pyelonephritis, chronic
Calculus
1
3
1
4
3
1
2
Total
5
10
F. Abdominal Diseases
Diagnosis
Primary
Secondary
Adhesions, peritoneal. . .
Appendicitis
Hernia, inguinal
Ileus, paralytic
No disease
Obstruction,
small intestine
2
2
1
1
2
3
1
1
Total
8
5
A]>ril, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
IX. OPERATIVE PROCEDURES
A. Vulva
D. Tubes
Operations
Bartholin Gland, excision
Bartholin Gland, I&D . . .
Biopsy
Other".
Vulveetom.v, complete . . .
Vulvectomy, radical
Hymenotomy
Total
B. Vagina
Biopsy
Colpoperineorrhaphy
Colpoplasty, anterior
Colpoplasty, posterior
Colpoplasty, anterior and posterior
Colporrhaphy
Colpotomv, diagnostic
Other. . . ."
Radioactive substances, insertion of
Total
205
C. Uterus and Cervix
Cervix, biopsy
Conization
Dilation, cervix
D&C, uterus, diagnostic
D&C, uterus, incomplete abortion. .
Excision, local, cervix
Hysterectomy,
radical and lymph node
Hysterectomy, subtotal
Hysterectomy, total abdominal ...
Hysterectomy, total vaginal
Hysteromj'omectomy
Hysteropexy, other types
Other
Radioactive sub. inserted into cervix
Radioactive sub. inserted into uterus
Trachelectomy
Trachelorrhaphy
Uterus, insufflation of
Hysterotomy
Partial pelvic extent., No. American.
Total
425
49
2
450
2
2
134
55
4
1
13
90
88
3
1
3
3
1
Ligation
Salpingectomy, unilateral, partial..
Salpingectomy, bilateral, partial. . .
Salpingectomy, unilateral, complete
Salpingectomy, bilateral, complete.
Salpingo-oophorectomy, unilateral .
Salpingo-oophorectomy, bilateral . .
Salpingoplasty
Salpingostomy
Total
E. Ovary
Operations
Number of
Patients
7
Oophorectomy, unilateral, complete.
Other "
8
14
Drain of ovary, cyst, abscess, etc. . . .
Oophorectomy, unilat., partial
Oophorectomy, bilat., complete ....
1
3
1
Total
34
F. Urinary System
Bladder, biopsy
Cystectomy
Cystoscopy, diagnostic.
Cystoscopy, therapeutic
Ileal Loop
LVeterostomy
Ureterectomy
Total
1427
Vol. 51, No. 2
DEPARTMENT OF OBSTETRICS AND GYNECOLOGY— ANNUAL REPORT
L\. OPERATIVE PROCEDURES (Cont.)
G. Abdominal and Others H. Irradiation
Diagnosis
Number of
Patients
18
40
4
112
6
Mesentery, biopsy of
2
44
Peritoneocentesis
3
4
Proctoscopy
Omentectomy
21
1
Total
257
Type
No. of Times
Other
51
89
Total
140
X. MORBIDITY AND COMPLICATIONS OF OPERATIONS
A. Minor Single
455
72
2. Causes of Morbidity
Number
Cause unknown
57
10
3
1
1
Others
Pulmonarj-
Septicemia
Total
72
3. Complications
Number
Cystitis
1
1
3
4
Paralytic ileus
Secondary Anemia
Other. . ."
Total
9
B. Minor Multiple
1. Total
Number
Morbidity
8
2
2. Causes of Morbidity
Number
Cause unknown
2
3. Complications
Number
1
'Total
1
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
X. MORBIDITY AND COMPLICATIONS OF OPERATIONS (Cent.)
C. Major Single D. Major Multiple
1. Total
Number
Morbidity
425
179
2. Causes of Morbidity
Number
Abd. wound infection.. ,
Cause unknown
8
106
1
1
8
1
51
3
Pulmonary
Thrombophlebitis
Other
Total
179
3. Complications
Number
Atelectasis
Paralytic ileum
Postoperative
hemorrhage
Pulm. embolism
Pj-elonephritis
Respiratory disease ...
Secondary anemia
Urinary retention
Wound infection
Other
1
9
1
1
2
5
10
2
7
25
11
1
Evisceration
Total
75
1. Total
Number
Morbidity
8
5
2. Causes of Morbidity
Number
Abd. wound infection.. .
Pelvic abscess
Cause unknown
Peritonitis
Total
5
3. Complications
Number
Paralytic ileum
Wound breakdown
1
1
Total
2
DEATHS
L.W. UH -26-87-98, 25 yr. old W.F. ad. 1/7/64 V.G.
Primarv Adenocarcinoma of Ovary. Died
1/17/64 of Small Bowel Obstruction.
M.M. UH-27-06-54, 59 yr. old W.F. ad. 1/17/64 R.S.
Carcinoma of Cervix. Died 2/5/64 of
Congestive Heart Failure.
M.T. UH-21-74-84, 64 yr. old C.F. ad. 2/3/64 L.J.
Carcinoma of Cervix. Died 2/15/64 of
Carcinomatosis.
L.B. UH-27-25-23, 52 yr. old C.F. ad. 2/7/64 F.R.
Carcinoma of Cervix. Died 2/22/64 of
Atelectasis, right and Pneumonitis, left.
A.N. LTH-16-88-63, 50 yr. old C.F. ad. 6/26/64
Hydronephrosis. Died 8/1/64 of Chronic
Hydronephrosis.
UH-13-45-14, 33 yr. old C.F. ad. 8,'28/64
Carcinoma of Cervix. Died same day of
Bronchial Pneumonia.
UH-26-63-60, 54 yr. old W.F. ad. 8/28/64
Carcinoma of Cervix. Died 9/24/64 of
Carcinomatosis.
LTI-29-75-35, 72 yr. old C.F. ad. 9/15/64
Cystadenocarcinoma-serous. Died 9/28/
64 of LTremia and Intestinal Obstruction.
I,TH-30-00-70, 55 yr. old C.F. ad. 11/7/64
Adenocarcinoma of Uterus. Died 11/12/
64 of Acute Heart Failure.
Vol 51. No. 2
ALUMNI ASSOCIATION SECTION
President's Letter
MEDICAL
ALUMNI ASSOCIATION
Officers 1963-66
C. Parke Scarborough, M.D.
President
Howard B. Mays, M.D.
President-elect
Lewis Klair Woodward. M.D.
Vice-President
John A. Moran, M.D.
rice-President
Morris Nicholson. M.D.
rice-President
Walter E. Karfgin, M.D.
Treasurer
Theodore Kardash, M.D.
Secretary
William H. Triplett, M.D.
E.reciitive Director
Mrs. Louise Girkin
Executive Secretary
Board of Directors
William J. Supik, M.D.
Hugh B. McNallv, M.D.
Emmanuel A. Schimunek, M.D.
William H. Kammer, Jr., M.D.
Robert B. Goldstein, M.D.
John D. Young, Jr., M.D.
Harry C. Bowie, M.D.
John O. Sharrett, M.D.
Theodore E. Stacy, M.D.
Secretary
Gibson J. Wells, M.D.
ex-officio
J. Howard Franz, M.D.
ex-officio
No
nating: Committee
J. Howard Franz, M.D.
Emmanuel Schimunek. M.D.
WiLFORD ToWNSHEND, Jr., M.D.
Donald H. Dembo, M.D.
C. Parke Scarborough, M.D.
ez-officio
E. I. CORNBROOKS, M.D.
William H. Triplett, M.D.
Representatives to
Editorial Board. BULLETIN
John C. Krantz, Jr., Ph.D.
John F. Savage, M.D.
Arthur G. Siwinski, M.D.
C. Parke Scarborough, M.D.
Representatives to
Faculty Board (3 year term)
C. Parke Scarborough, M.D.
Howard B. Mays, M.D.
Fellow Medical Alumni:
This letter for the April Bulletin would normally
have been sent to the editor in February, in an eflort
to let the Alumni Association members know our plans
for the annual reunion on the weekend of May 5-6-7,
1966.
Unfortunately, the January, 1966, issue of the Bul-
letin with the Presidential Letter telling of our pre-
liminary efTorts to plan a good Alumni Day for your
returning members did not come off the press in time
to be sent out before the Alumni Day activities. Instead
of your receiving it in January, it has not appeared as
of the last week of May. The delay was occasioned by
a consecutive series of unfortunate delays which the
editor assures us will not recur. I understand that the
April issue is now on press and will appear in June.
The July issue will mark the return of the Bulletin to
a regular schedule. There are several things that I
think are important for the Alumni to know.
One is that the President of the Alumni Association
and the Board of Directors of the Alumni Association
collaborate with the Bulletin in its publication but do
not assume the responsibility for printing it. It is our
aim to cooperate with the editor and his staff and to
offer all of the help the Alumni office can give. Next, it
should be pointed out to the Alumni that the annual
dues of the Medical Alumni Association is $7.00. A
subscription to the Bulletin (4 issues) amounts to
$3.00. The type of bill sent to each alumnus is a type
approved by the postal authorities. The Alumni Asso-
ciation collects the subscription funds and remits them
to the Bulletin.
There have been criticisms of the Bulletin. There
has been praise for the Bulletin. There have been criti-
cisms for the Annual Alumni meeting. There have
been criticisms of many things in-so-far as the Alumni
Association is concerned. There are always those who
criticize. There also has been much praise. I have
Continued on page xxxii
April. 1966 xxxi
BVLLETIX OF THE SCHOOL OF MEDICIXE. UXIJ-ERSITV OF MARVLAXD
PRESIDENT'S LETTER (Cont.)
1
heard two criticisms of the Alumni Day activities and have heard hundreds of laud-
atory remarks. I feel that if those who have justifiable criticism would come to the
Alumni meetings and help make the necessary decisions at the annual business meet-
ing, it would not then be necessary for them to write in letters of criticism after
decisions have been made. Out of the thousands of Alumni, less than one hundred
turned out for the annual business meeting this year. I do feel that a keener interest
on the part of all Alumni is necessary for a smoothly functioning organization.
C. PARKE SC.'\RBOROUGH, M.D.
President
Pay Your Medical Alumni Dues
Directly to School of 3Medicine
In recent months, confusion has arisen concerning the
j)lace where physicians who wish to pay their Ahinmi dues
may send their check. The following will serve to clarify this
issue.
There are two Alumni Associations at the University of
Maryland. There is the General Alumni Association with
offices at College Park. Of particular interest to the School
of [Medicine, is the Medical Ahmmi Association with offices
at Lombard and Greene Streets in Davidge Hall.
Physicians who are graduates of the School of INIedicine
are urged to maintain their active association and affiliation
Mith their Alnia Mater through the payment of their annual
dues for which bills are sent at the end of each school year
(June). Those Alvimni who are interested in the General
Alumni Association at College Park should seek membership
through this organization, the offices of which are at College
Park. All scientific sessions, alumni news and the Bvilletin of
the School of Medicine comprise the activities of the [Medical
Akimni Association. A magazine Maryland is the publication
of the General Alumni Association.
Vol. 51, Xo. ^
Class
NOTES
Elsewhere in this edition you will
find a "tear out" page, for reporting
Alumni News to the Bulletin. This is
not an idle gesture.
Your achievements, fellow alumnus,
are of interest to your classmates. They
constitute a reward to the faculty, are a
challenge to the younger physicians, and
are an item of prestige for the Univer-
sity. Please cooperate with us by for-
zvarding news of yourself or any alumnus
to the Bulletin. Thank you.
P & S 1903
Dr. F. W. Mayer of 1830 James Avenue,
St. Paul, Minnesota, writes: "The October
1965 edition of the Bulletin is worthwhile
keeping as it goes back a few centuries in
medical education in the United States.
"As an old timer, I send you a check to
help the good cause. Not many members
of the P & S class of 1903 are around any
more and I wonder if Dr. Ale.xius McGlan-
nan is still among the living. He was one
of my most esteemed teachers not in a
surgical subject but mostly physiologic
chemistry and clinical laboratory." (Dr.
Mayer enclosed a contribution toward the
publication of the Bulletin.) (Dr. Alexius
McGlannan died on February 25, 1940 at
the age of 67 — Editor.)
CL.\SS OF 1914
Dr. Theodore M. Davis, eminent urologist
and recipient of the 1965 Alumni Honor
Award and Gold Key, has been nominated
Valentine lecturer by the urological section
of the New York Academy of Medicine.
Dr. Davis will present a paper entitled "Ex-
periences in Transurethral Resections" il-
lustrated with motion pictures of his origi-
nal work in the development of this tech-
nique. The award, presented annually
carries a considerable honorarium, a medal
and a plaque with it.
CLASS OF 1925
Dr. Samuel C. Glick, associate professor
of pediatrics, has been elected vice-president
of the National Board of Trustees of the
Phi Delia Epsilon Fraternity.
Dr. Thomas B. Turner, dean of the school
of medicine of the Johns Hopkins Uni-
versity, has been recently elected president
of the Association of American Medical
Colleges.
CLASS OF 1928
Dr. Israel Kaufman, for a number of years
head of the New York City Department of
Health, Division of Tuberculosis and for
the past 20 years physician-in-charge of
the chest clinic, will shortly retire from the
Department of Hospitals and the University
of the State of New York. Dr. Kaufman
has been a member of the faculty of the
university for the past ten years serving as
assistant professor of clinical medicine. He
was formerly associated with Kingston Ave-
nue Hospital where he served as attending
physician and director of pulmonary dis-
ease. Following the closing of that insti-
tution he became connected with the Kings
County Hospital Center as an attending
physician, serving as president of its medical
board for three years. Dr. Kaufman will
continue in the private practice of internal
medicine, specializing in diseases of the
chest.
CLASS OF 1929
Dr. Jacob H. Conn, assistant professor of
psychiatry at the Johns Hopkins University
School of Medicine, was recently elected
president of the American Board of Medical
Hypnosis at its 17th Annual Meeting held
in Los Angeles, California. Dr. Conn is also
a past president of the society and recipient
of the society's 1965 Schneck Award for
significant contributions to the development
of medical hypnosis. He was the first private
practicing psychiatrist in Maryland to be
certified by the American Board of Psy-
chiatry and later by the Neurology Board in
1959.
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
CLASS OF 1934
Dr. Louis V. Blum has been elected presi-
dent of the HIAS, the Jewish Welfare Fund's
migration service agency. Dr. Blum suc-
ceeded Paul L. Cordish who has retired.
Dr. Ralph B. Garrison currently serves as
chairman of the board of school trustees of
Hamlet, North Carolina. After his gradu-
ation, he served as a junior resident at the
Maryland House of Correction and an in-
ternship at the Baltimore City Hospital.
Dr. Garrison helped organize the Hamlet
civic club, the community's first organiza-
tion of that type, and was its second presi-
dent. Dr. Garrison is also active in a num-
ber of other civic and governmental
organizations.
CLASS OF 1935
Dr. George F. Schmitt, F.A.C.P., is the
author of a recently published popular
book entitled Diabetes for Diabetics.
CLASS OF 1936
Dr. W. Kenneth Mansfield, obstetrician and
gynecologist, has been recently elected head
of the medical staff of the Franklin Square
Hospital.
CLASS OF 1937
Dr. Everett S. Diggs has announced the
relocation of his office for the practice of
gynecology and female urology to the
Greater Baltimore Medical Center, 6701
North Charles street, Baltimore. Several
years ago, Dr. Diggs was named head of
the department of gynecology at the then
Women's Hospital of Maryland which has
been reorganized as a large North Balti-
more General Hospital in new quarters
erected on the former grounds of the
Sheppard Pratt Hospital, land purchased
for this purpose of constructing a large gen-
eral hospital to serve this section of the
growing metropolitan area.
CLASS OF 1938
Dr. John Z. Bowers, president of the
Josiah Macy Junior Foundation of New
York City, presented the annual Beaumont
Memorial Lecture at Yale University School
of Medicine on January 28, 1966. Dr.
Bowers' subject was "From Chinese Medi-
cine to Western Medicine in Japan." Dr.
Bowers is a recent author of a volume re-
lating to a study of Japanese medicine, the
outcome of more than two years work in
the Orient.
Dr. Joseph M. George, Jr. of 637 East
Sahara avenue, Las Vegas, Nevada, has
been elected president of the Nevada State
Medical Association for the year 1965-66.
Dr. Edward Siegel of 44 Broad street,
Plattsburgh, N. Y., has been re-elected as
chief of staff of the Physician's Hospital,
Plattsburgh, N. Y.
CLASS OF 1940
Dr. Lester Caplan has been named chief
of pediatrics of the North Charles General
Hospital. Dr. Caplan also served on the
Executive Committee and the National
Board of Trustees of the Phi Delta Epsilon
Medical Fraternity.
Dr. William R. Piatt, pathologist and head
of the department of pathology at the
Missouri Baptist Hospital in St. Louis, is
the editor of the section "New and Useful
Technics" published in the Bulletin of Path-
ology of the American Society of Clinical
Pathologists. Dr. Piatt is the author of
numerous scientific papers including a
widely used publication on cells of spinal
fluid and brain cysts.
CLASS OF 1941
Dr. Kenneth L. Zierler is a member of
the Editorial Board of the Bulletin of the
Johns Hopkins Hospital.
CLASS OF 1943
Dr. Frank Mason Sones, Jr., Director, de-
partment of pediatric cardiology and cardiac
Vol. 51, No. ?
ALUMNI ASSOCIATION SECTION
laboratory of the Cleveland Clinic Founda-
tion, was a recent recipient of one of the
Modern Medicine awards for 1965.
CLASS OF 1944
Dr. Abraham Lilienfeld, a member of the
faculty of the Johns Hopkins University,
has been named a member of the newly
organized international agency for cancer
research. Dr. Lilienfeld was selected among
scientists from seven countries including the
United States which he will represent as
a member of the advisory council. The
organization is designed not to perform re-
search on its own but makes grants for
projects, toward which its seven members
contribute. The agency secretariat is headed
by the director-general of the World Health
Organization.
CLASS OF 1946
Dr. Jerome D. Nataro, Bluegrass lane,
Levittown. N. Y. has been recently certi-
fied by the American Board of Otolaryng-
ology.
CLASS OF 1947
Dr. Pascal D. Spino of Greensburg, N. C.
is currently serving as a volunteer on the
S. S. Hope. The ship this year will spend
a period of time in Nicaragua where Dr.
Spino will be joined by specialists in every
field of medicine. Dr. Spino has prepared
a series of lectures to be presented to medical
personnel in the Central American nation.
Thanks to the efforts of a friend of his,
Mrs. Antonio Rebolledo of Greensburg, Dr.
Spino's lectures have been translated into
Spanish.
CLASS OF 1948
Dr. Donald I. Mohler, Jr., of 975 Ryland
Street, Reno, Nevada, has been elected
Chief of Staff of the Washoe Medical Center
in Reno. Dr. Mohler also serves as Chief
of the Department of Obstetrics and Gyne-
cology of the same hospital.
CLASS OF 1952
Dr. Norton Spritz of 445 East 68th street,
New York City, has been appointed as-
sociate professor of medicine at the Cornell
Medical College where Dr. Spritz will direct
the Lipid Metabolism Laboratory of the Cor-
nell Medical Division at Bellevue Hospital.
Dr. Spritz assumed this new position on
July 1, 1965.
CLASS OF 1953
Dr. Leonard B. Click of the University
of Pennsylvania has been appointed assistant
professor of anthropology at the University
of Wisconsin, at Madison, Wisconsin.
Dr. Joseph E. Shuman of the 1400 South
Joyce street (Suite A 102), Arlington, Vir-
ginia, has recently been certified as a diplo-
mate of the American Board of Internal
Medicine.
CLASS OF 1956
Dr. Harold L Rodman of 1110 Spring
street, Silver Spring, Md. has been recently
certified a diplomate of the American Board
of Ophthalmology.
CLASS OF 1956
Dr. George T. Smith serves as Research
Professor of Pathology at the Desert Re-
search Institute of the University of Nevada.
Dr. Smith resides at 3293 Gypsum Road,
Reno, Nevada.
CLASS OF 1959
Dr. Robert S. Holt, who holds the position
of captain in the United States Air Force,
recently participated in a series of pro-
grams on the latest advancement in the
medical aspects of aviation and space travel.
Dr. Holt, who has served in Vietnam, is
currently on duty as a resident neurosurgeon
at the University Hospital in Baltimore.
April. 1966
Beatfjsi
CLASS OF 1902
Dr. Ernest Charles Lehnert of 3003 North
Charles Street, died October 25, 1965 at
the age of 85
CLASS OF 1904
Dr. Robert Emmett Houston died on
October 4, 1965 at his home, 411 East
Washington street, Greenville, S. C. Dr.
Houston, who had been retired a number
of years, was 87.
A native of Greenville, he was graduated
first from the University of Maryland School
of Pharmacy and later from the School of
Medicine. He immediately returned to
Greenville, later entering the specialty of
ophthalmology.
CLASS OF 1905
Dr. Archibald Wright Graham, of Box 563,
Chisholm, Minnesota, died October 18,
1965.
P & S 1905
Dr. William C. Stone, who served as health
officer in Carroll and Howard Counties for
more than sixty years, died on October 6,
1965. Dr. Stone was 85. Since 1924 he
had lived in Westminster with his home and
private medical oflBces at 121 East Green
street. He left the State health post in
1951 but had maintained an active practice
until his health failed early in 1965. He
was a native of Vermont and came to
study medicine at the College of Physicians
and Surgeons, now a part of the University
of Maryland School of Medicine. He served
his internship at the St. Agnes Hospital, later
serving in the same hospital as an assistant
resident in medicine.
Dr. Clyde W. Vick of 21 17 Jefferson Street,
Bluefield, West Virginia, died on December
4, 1965 at the age of 87.
CLASS OF 1906
Dr. Orel Nathan Chaffee of 820 Sassafras
street, Erie, Pennsylvania, died August 30,
1965 at the age of 89.
CLASS OF 1908
Dr. Charles William Cohn of Pittsburgh,
Pennsylvania, died on August 15, 1965. Dr.
Cohn was 79.
CLASS OF 1910
Dr. Thomas Dalton Crouch of Box 97,
Stony Point, N. C, died on August 8, 1965
at the age of 87.
Dr. Harry R. Seelinger of 8920 Semmes
avenue, Norfolk, Virginia, died May 2, 1965
at the age of 76.
Dr. Joseph Righton Robertson of 1968
Johns Road, Augusta, Georgia, died on
February 5, 1966.
CLASS OF 1911
Dr. Abraham Hornstein of 204 East Biddle
street, Baltimore, Md., died June 11, 1965.
Dr. Hornstein was 77.
P & S 1911
Dr. Hermon Simons Miller of 609 Wash-
ington street, Wilmington, Delaware died
on August 21, 1965 at the age of 76.
CLASS OF 1912
Dr. Silvia Jeremiah Roberts of 1432
North Second street, Harrisburg, Pennsyl-
vania, died August 20, 1965 at the age of
80.
P & S 1912
Dr. Albert E. Goldstein of 3505 North
Charles Street, Baltimore, died on February
22, 1966.
Dr. Goldstein, an internationally promi-
nent urologist, long active in the affairs of
Vol. 51, No. 2
ALUMXl ASSOCIATION SECTION
the School of Medicine and of the Uni-
versity as a whole, was honored by many
friends prior to his death, after a lingering
illness. Dr. Goldstein's obituary will ap-
pear in a forthcoming edition of the Bulletin.
CLASS OF 1913
Dr. Samuel Allen Alexander of 1830 Eye
street in Washington, D. C, died on Septem-
ber 22, 1965. Dr. Alexander was 73.
Dr. William Walter Sirak of 1015 Car-
negie avenue, Cleveland, Ohio, died July
20, 1965 at the age of 74.
CLASS OF 1914
Dr. George W. Bishop of Pasadena, Mary-
land, died on July 6, 1965. Dr. Bishop was
77.
P & S 1914
Dr. Byron W. Steele of Mullens, West Vir-
ginia, died on January 29, 1966. A native
of Moundsville, West Virginia, Dr. Steele
was actively engaged in the practice of medi-
cine when he was stricken early in Novem-
ber of 1965.
Dr. Steele received his Bacheloriate De-
gree from Marshall University in 1910 and
following his graduation was commissioned
a First Lieutenant in the Army Medical
Corps. He served in World War I in field
hospitals in France. He then returned to
Mullens, West Virginia where he remained
as a practitioner until his death.
CLASS OF 1915
Dr. Vincent J. Demarco, of 1642 Poplar
avenue, Memphis Tennessee, died October
27, 1965. Dr. Demarco was 73.
CLASS OF 1917
Dr. Clarence Mansfield Reddig (Col.,
Medical Corps, U. S. A.) retired, of 3 Red
Cross avenue, Newport, Rhode Island, died
April 24, 1965. Dr. Reddig was 72.
CLASS OF 1918
Dr. Clarence E. Macke of Ellicott City,
Maryland, died on January 15, 1966.
A native and life long resident of Balti-
more, Dr. Macke practiced pediatrics until
his retirement in 1957. He worked closely
with the Bureau of Recreation throughout
his life and was a member of the Lutheran
church.
Dr. Irwin O. Ridgely, of 202 Edgevale
road in Baltimore, died on December 28,
1965. Dr. Ridgely was 73.
Dr. Ridgely was a native of Bartholows,
Frederick county and was graduated from
the Frederick County School and from
Washington College. Following his gradu-
ation from the University of Maryland,
he interned and later took postgraduate
courses in surgery at the Mercy Hospital
becoming ultimately an associate surgeon
at both the Mercy and the University
Hospitals. Dr. Ridgely, for many years as-
sociated with Drs. Henry F. Bongardt and
Patrick C. Phelan, specialized in industrial
surgery. He was a member of the Balti-
more City Medical Society, the Medical and
Chirurgical Faculty of Maryland, the
American Medical Association and the
Southern Medical Association. He also was
a Fellow of the American College of
Surgeons.
CLASS OF 1916
Dr. Foster A. Beck, 323 North 7th street,
AUentown, Pennsylvania, died September
27, 1965.
Dr. Thomas M. Dominguez-Rubio, of 1
Baldorioty Street, Guayama, Puerto Rico,
died October 24, 1963.
Dr. James Parks Rousseau of 808 Oak-
lawn avenue, Winston-Salem, North Caro-
lina, died September 29, 1965. Dr. Rous-
seau was 69.
Dr. Frank Sabiston of P.O. Box 530,
Kinston, North Carolina, died on June 17,
1965 at the age of 72.
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
CLASS OF 1920
Dr. Nathan J. Davidov of 3218 Eastern
avenue, Baltimore, Md. died on November
25, 1965.
Dr. James William Skaggs of Nitro, West
Virginia, died July 19, 1965 at the age of 68.
CLASS OF 1921
Dr. Harold C. Pillsbury, Sr. of 1800 North
Charles street, died on January 12, 1966.
Dr. Pillsbury was 67.
Dr. Pillsbury practiced both general and
industrial surgery and was active on the
staff of the St. Joseph's Hospital in Balti-
more, the institution where he received his
surgical training.
CLASS OF 1922
Dr. Lewis J. Doshay of 710 West 168th
street, New York, died recently.
CLASS OF 1924
Dr. Jerome F. Granofif of 37-12 75th
Street, Jackson Heights, New York, died
November 8, 1965. Dr. Granoff was 64.
CLASS OF 1925
Dr. Leo T. Brown of 1621 New Hampshire
avenue, N.W., Washington, D. C, died on
January 14, 1966.
Dr. William Earl Lennon of 122 West
Central avenue, Federalsburg, Maryland,
died on December 31, 1965. Dr. Lennon
was 67.
A native of Manteo, North Carolina and
a graduate of the University of North Caro-
lina, Dr. Lennon was engaged in general
practice in Federalsburg since 1926.
CLASS OF 1926
Dr. Paul Eanet, a surgeon who received
a congressional citation for his work with
Selective Service System during World War
II, died in Washington, D. C. on September
25, 1965, at the age of 62. Dr. Eanet served
on the staffs of several hospitals in the
District of Columbia.
CLASS OF 1927
Dr. T. Nelson Carey, Professor of Clinical
Medicine at the University of Maryland and
who was to receive the 1966 Alumni An-
nual Honor Award and Gold Key, died at
Mercy Hospital on March 11, 1966 after
a short illness. Dr. Carey's obituary will
appear in a forthcoming edition of the
Bulletin.
CLASS OF 1928
Dr. William H. Varney of 120 Belvedere
avenue, Washington, New Jersey, died on
January 10, 1966. Dr. Varney was 61.
He began practice in Washington, New
Jersey shortly after his graduation from the
School of Medicine and his internship at the
University Hospital. Dr. Varney was a
member of the American Medical Associa-
tion, the International College of Surgeons,
the Warren County (New Jersey) Health
Board and was executive secretary of the
Warren County Division of the American
Cancer Society. He also served as a director
of the Warren County Tuberculosis and
Health Association.
CLASS OF 1929
Dr. Phillip P. (Paul) Cohen of 104 South
Church street. Snow Hill, Maryland, died
November 26, 1965.
CLASS OF 1931
Dr. H. Vernon Langluttig, formally a mem-
ber of the staff of the University Hospital
and at one time head of the chest division
of the Baltimore City Hospitals, died on
February 1, 1966 in Mt. Vernon, Missouri.
Dr. Langluttig was 61.
A native of Baltimore and an alumnus
of the Baltimore Polytechnic Institute, Dr.
Langluttig received his Bacheloriate Degree
from the Johns Hopkins University. Follow-
ing his graduation from the School of Medi-
cine he interned at St. Joseph's Hospital
and served a residency in medicine at the
University Hospital. He later became active
on the teaching faculty rising to the rank
of clinical professor of medicine. In 1942
Vol. 51, No. 2
AI.UMXI ASSOCIATIOX SECTION
he volunteered for military service and spent
two years in the Fiji Islands. In 1957. he
returned to the City Hospitals where he
served as Chief until accepting a post of
Chief of the Service of the Missouri Chest
Center in Mount Vernon, Missouri.
CLASS OF 1934
Dr. Charles L. Goodhand of 1100 Market
street, Parkersburg, West Virginia, died Sep-
tember 10, 1965 at the age of 58.
I Dr. Milton Levin died on November 16,
1965 at the Lutheran Hospital of Maryland.
IT WAS my good fortune <o have known
Dr. Milton Levin since his student days.
He was graduated from the University of
Maryland in 1934. He did his internship
at Lutheran Hospital, which at that time
was known as West Baltimore General. He
served three years as a house officer, com-
pleting his residency in surgery in 1938.
This was followed by post-graduate work at
the Philadelphia General Hospital. He was
always a good student and made every
effort to be informed of the latest advances
in medicine. His professional life was dedi-
cated to the practice of clinical surgery. To
this he gave his whole being and unstintingly
to his patients. He was never content with
less than the best for his patients. The im-
pressive qualities of Dr. Levin were his
kindliness and humility. He was ever the
solicitous servant to his patients. In ad-
dition to his feeling of professional re-
sponsibility he evidenced a personal concern
for the overall welfare of his patients. This
T can state from personal experience of his
art and craft. In addition, he was interested
in the administrative side of his profession.
It was in this facet of medicine that he
willingly devoted himself generously. In his
executive positions he was guided by a
sense of fairness and balance that was re-
freshing. WTien the occasion required, he
could exhibit firmness and courage for the
position he thought right. He practiced
medicine as Job practiced his religion with
the material reward being of the least con-
cern. Truly he was a real image of the good
doctor. His personal religion was to be
"his brother's keeper." He was a devoted
husband and father of two sons. His con-
cern for his home could be best understood
when he said at the time of his final stay
at the hospital that he didn't think he'd
see his home again.
His practice of surgery was limited en-
tirely to the Lutheran Hospital. Truly it
can be said that he personified the image
of a "Good Shepherd." His passing will
be a loss deeply felt by his loved ones,
friends and patients.
Louis A. M. Krause, M.D.
CLASS OF 1937
Dr. Mitchell F. Kunkowski of 2529
Eastern avenue died on December 25, 1965
at the age of 53.
A native of Baltimore and an alumnus of
Lions College High School in Pennsylvania,
Dr. Kunkowski later attended the University
of Maryland and following his graduation
from the School of Medicine served actively
with the United States Army in World War
II. He served his internship at the St.
Joseph's Hospital and later studied internal
medicine and served a residency at the
Maryland General Hospital.
CLASS OF 1943
Dr. Joseph F. McMullin of 127 E. Edge-
wood drive, Stroudsburg, Pennsylvania, died
on August 19, 1965 at the age of 49. Death
was due to drowning.
Dr. E. Thornton Pfeil, Jr., died on August
20, 1965 at the age of 45. Death was caused
by leukemia.
Dr. Pfeil, who lived at 2021 North Central
Avenue in Phoenix, Arizona, was a native of
Baltimore and received the Bachelor of
Science degree from the University of Mary-
land and later his Doctor of Medicine de-
gree from the same school graduating Cum
Laude in the class of 1943.
Following an internship at the University
Hospital, he completed his residency in
neurosurgery under the joint directorship of
Dr. Charles Bagly, Jr. and James G. Arnold.
April, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
For a period of time, Dr. Pfeil served as
fellow in neuropathology. Upon completion
of his residency, he was commisisoned in
the Army of the United States attaining a
rank of major. During his military service
at the Letterman General Hospital and later
he held the position of chief of neurosurgery
at the Brooke Army Medical Center, San
Antonio, Texas.
Dr. Pfeil was a member of many pro-
fessional societies including the state and
country societies, the American Medical
Association, the Harvey Gushing Society, the
American College of Surgeons, the American
Board of Neurological Surgeons and the
Congress of Neurological Surgeons includ-
ing the Gold Headed Cane Club. Dr. Pfeil
came to Phoenix in 1953 and was first as-
sociated with Dr. John Eisenbeiss and later
with Dr. George Hoffman. He served as
chief of neurosurgery at the Memorial
and the Maricopa County General Hospitals
and had staff membership in the St. Joseph's
Hospital, Good Samaritan Hospital, St.
Luke's, Lincoln, Mesa Southside and
Doctors Hospital.
In a tribute to Dr. Pfeil published in the
November 1965 Arizona Medicine, it is
stated "Thorny had the gallantry of a knight,
the persuasiveness of Cervantes, and the
ebullience of the music man. Others re-
member him for his sportsmanship, some for
his clubmanship and perhaps all of us for
his professional activities, many and varied.
"If Harvey Cushing and his contempor-
aries are considered the founders of modern
neurological surgery in this country, then
Dr. Pfeil and his contemporaries would
perhaps fall into the third generation there-
after. It is this group of neurosurgeons, with
angiography and other similar procedures,
who have had increased exposure to roentgen
irradiation."
Not only was Dr. Pfeil an excellent and
respected clinical surgeon but he had con-
tributed abundantly to the scientific litera-
ture as well. A meticulous and precise tech-
nician, the practice of neurosurgery has in-
deed lost a most honored and valued mem-
ber.
Dr. Pfeil is survived by his wife Virginia,
a son, Edgar, and a daughter, Carolyn.
Vol. 51, No. 2
BULLETIN School of Medicine
UniversU/j of Manj/oj/d
\OHMl-: SI jlL^' IVW. MMBIK i
TABLE OF CONTENTS
ORIGINAL ARTICLES
Frequency and Power Considerations in the Use of
Alternating Current Defibrillators - —
C. D. Ferris. D.Sc. T. W. Moore, M.S., R. A. Cowley, M.D.
Tolnoftote, A Specific Antifungal Agent.
Harrx M. Rohiiison. Jr.. M.D.
MEDICAL SCHOOL SECTION
Dean's Letter —. _.
Rolph P. Truitt, 1886-1966- __
Faculty Notes — - -
Publications of Staff of School of Medicine 1964-1965.
ALUMNI ASSOCIATION SECTION
xliii
xlv
Camera Views
xlviii
Treasurer's Report of Alumni
Pre-Commencemenf and Dean'
Association
196A
li
lii
Camera Views
liii
Class of 1966 Internships .
July, 1966
35
Frequency and Power Considerations in the
Use of Alternating Current Defibrillators
C. D. FERRIS, D.Sc, T. W. MOORE, M.S., R. A. COWLEY, M.D.
Introduction
Most investigations of the role of
frequency in successful defibrillation at-
tempts have merely compared 60 cps.
alternating current with direct cur-
rent.'^' 2) The purpose of the research
reported in this paper was to study the
effect of frequency in general with respect
to closed chest defibrillation. A series
of experiments was carried out using 36
dogs and involving nearly 500 attempts
at defibrillation. Disc electrodes measur-
ing 7.5 cm. in diameter were placed on
each side of the chest of the animals.
Defibrillation by electric shock is
thought to be the result of complete tetanic
contraction of all cardiac muscle fibers in
response to a large shock. This is fol-
lowed by a period of cardiac standstill
and then by recovery of normal heart
action, although in some cases an elec-
tronic pacemaker must be used to re-
store normal sinus rhythm. Since the
achievement of an action potential
ultimately depends upon the reduction of
the charge dilTerential across a membrane,
it would seem that the magnitude and
duration of the current applied at the
membrane should be the most significant
factors at any given frequency. (^' '*'>
Experimenters who use direct current
defibrillation methods *-' -^' measure
energy expended rather than current,
probably because the decaying nature of
the current waveform prohibits the use
of a convenient numerical value for the
current amplitude. From our analysis of
the data obtained with ac defibrillators
and from an examination of the literature
pertaining to dc defibrillators, we feel that
total energy expended per se is not the
determining factor for effective defibrilla-
tion. Energy expended as a function of
time may show correlation with effective
defibrillation. Measurement of expended
energy introduces many artifacts such as
variable electrode contact resistance and
electrode polarization which may vary
widely over a series of measurements.
As a result of electrode polarization, there
is a voltage drop at the electrode-electro-
lyte interface when current is drawn.
Thus the voltage appHed across the defi-
brillation electrodes measured at the elec-
trodes is not the voltage applied across
the chest of the animal. ''■ '■' For these
reasons, the decision was made to use cur-
rent magnitude as an independent vari-
able, since this may be measured easily,
and to work with a fixed defibrillation
pulse duration of 0. 1 sec.
From the Department of Electrical Engineering, Col-
lege Park and Division of Thoracic Surgery, Department
of Surgery, University of Maryland School of Medicine,
Baltimore, Maryland. Supported in part by U. S. Public
Health Service Grant No. HE-04595.
Results
The data were analyzed by the follow-
ing technique: The experimental points
36
rr.RRIS. MOOKF.. COtn.i:)—.tLTERN.lTL\G CVRRKXT DEFIBRILLATOKS
(current reading as a function of
frequency and success or failure of de-
tibriilatory shock) were separated into
five frequency ranges — below 80 cycles/
second, 80-100 cps., 100-200 cps., 200-
250 cps., 250-300 cps. For each range
of frequencies, the percentage of success-
ful delibrillation attempts at various cur-
rent amplitude levels was calculated.
Equal numbers of tests were made in
each frequency range so that curves
plotted from the data would have equal
reliability over their extents. From these
curves, the current levels which indicated
60% and 80% probability of suc-
cessful defibrillation were determined.
From these points, curves were then
plotted showing current as a function of
frequency for 60% and 80% confi-
dence of successful defibrillation. These
curves (Figs. 1 and 2) indicate that as
frequency of the defibrillating signal is
increased, increased current is required.
Lown and his co-workers'" in 1962,
using various capacitor discharge circuits,
found that a 70 joule discharge gave
65% reliability of defibrillation. Bala-
got <''' reported good results with a dc
defibrillator which supplied 80 joules into
a 100 ohm resistive load. The results of
our experiments, when extrapolated to
zero frequency, are in close agreement
with the values reported in the literature.
In fact, our results indicate that slightly
lower energy levels are required when low
frequency alternating current stimulation
is employed. Figure 3 indicates the
energy required for successful defibrilla-
tion with a level of confidence of success
with the first shock of 80%. The dur-
ation of the defibrillatory shock in all
cases is 0.1 second and the magnitude of
the impedance presented to the defibrilla-
tory electrodes varies from 50 to 100
ohms, in part caused by the varying sizes
of the experimental animals.
6.0
5.5
5.0 ■
4,5
4.0
3.5
3.0
FiK. 1. Electrode current
frequency for 80';/ confider
of successful defibrillat
300 FRSOUENCr (CPS)
a function of applied
300 FREOUENCr ICPS)
s a function nf auplied
SO % CONFIDENCE LEVEL
60% CONFIDENCE LEVEL
300 FREOUENCr ICPS)
Julv. 1966
37
BULLETIX OF THE SCHOOL OF MEDICINE, UNU'ERSITV OF MARYLAND
To find power levels within the body
during the application of a defibrillatory
shock, disc electrodes were implanted in
several animals. The electrical power
level at the heart during the defibrillating
signal was measured by suturing stain-
less-steel-wire crocheted electrodes (1.5
cm. 2) on opposing sides of the myo-
cardium. Connections to these electrodes
were brought out to the skin surface of
the animal. The animal was permitted
to heal for six weeks. By direct measure-
ment, the impedance presented to the
electrodes by the heart was found to be
approximately 900 ohms at 60 cps. It
was found that at 60 cps. (the usual
frequency employed by ac defibrillators),
less than 1% of the power applied at
the chest surface appeared at the heart.
Appendix
All of the experimental animals were
anesthetized using standard Nembutal
I.V. Repeated injections were required to
maintain an approximately constant level
of anesthesia as the electric shocks
counteracted the effect of the Nembutal.
Electrode contact problems were also
investigated to learn their effect upon
studies of this nature. Studies were con-
ducted using saturated-saline-wetted elec-
trodes applied to the skin directly, satur-
ated-saline-soaked gauze pads between
the electrodes and the skin surface, and
standard electrode paste between the elec-
trodes and the skin. Beforehand, the
animal's skin had been prepared by shav-
ing and cleansing with germicidal soap.
The quality of the electrode contact was
evaluated by measuring the impedance
presented to the electrodes by the chest
region of experimental animals under con-
stant electrode pressure.
It was found that electrode paste gave
the most unreliable and variable results.
The smallest variation was found with the
saline soaked gauze pads. The saline-
wetted electrodes gave uniform results but
a constant contact potential drop was
noted. Higher impedance values were
also noted in this last case.
References
1. LowN, B., et al.. "Comparison of Alter-
nating Current wtih Direct Current Electro-
shock Across the Closed Chest," Am. J. Cardi-
ol.. 10:223-233 (1962).
2. Mackay, R. S. and Leeds, S. E., "Physio-
logical Effects of Condenser Discharges," J.
Appl. Phy.tiol., 6:67 (1953).
3. Ferris, L. P., et al., "Effect of Electric
Shock on the Heart." Electrical En;.;iiu'criiig
(May, 1936).
4. Wiggers, C. J., "The Physiological Basis
for Cardiac Resuscitation from Ventricular Fi-
brillation . . . Method of Serial Defibrillation,"
Am. Heart J.. 20:413 (1940).
5. SCHWAN, H. p., "Electrodenpolarisation
und ihr Einfluss auf die Bestimmung dielek-
trischer Eigenschaften von Flussigkeiten und
biologischem Material." Zeit. f. Nariir.,
6b:3:121-129, (1957).
6. KOHLRAUSCH, F., Ann. Pliy.sik unci C hemic .
60:315 (1897).
7. Balagot, R. C, et al., "A Monopulse DC
Current Defibrillator for Ventricular Fibrilla-
tion." J. Thoracic and Cardiovas. Surg. (April.
1964).
38
Vol. 51, Nc: 3
Tolnaf'laUN A Specific Antifuiigal Agent
HARRY M. ROBINSON, JR., M.D.
ToLNAFTATE ( 0-2-naphth\i m, N-di-
methylthiocarbanilate), synthesized in
I960,"' is the first chemical compound
to have specific fungicidal activity on
topical application. Initial clinical studies
proved this drug to be effective in the
treatment of superficial mycotic infections
due to trichophyton rubrum, trichophyton
nientagrophytes. trichophyton tonsurans,
epidermophyton floccosum. microsporum
canis, microsporum gypseum. microspor-
um audouini. and microsporum furfur.'-'
Adverse effects to the topical applications
of the 1.0% solution or 1.0% cream
were not encountered in this investigation.
Double blind studies confirmed the thera-
peutic efficacy of the tolnaftate prepara-
tions. In subsequent in vitro and in vivo
studies '■'■■*' the spectrum, lack of toxicity,
freedom from adverse reactions, and
range of therapeutic specificity were dem-
onstrated.
Lesions due to Candida albicans do
not respond to local applications of the
tolnaftate preparations. Tinea versicolor,
tinea pedis, tinea cruris, and tinea cor-
poris due to the previously mentioned
dermatophytes respond promptly to treat-
ment with this drug, but it is ineffective
in onychomycosis and tinea capitis.
Tolnaftate is a colorless, odorless com-
pound which is soluble in most organic
compounds and insoluble in water. It
does not stain skin, hair or nails. The
solution contains 1.0% tolnaftate, and
ision of Dermatology, Department of
sity of Maryland School of Medicine.
0.1% butylatcd hydro.\ytoluene in poly-
ethylene glycol 400. The cream contains
1.0% tolnaftate in a vanishing cream
base.
This report contains the results of ex-
tended clinical trials and follow-up studies.
In all patients the diagnoses were estab-
lished by direct microscopic examinations
and cultures. The importance of labora-
tory confirmation of clinical impressions
cannot be overemphasized.
Three hundred twenty-three patients
who had superficial mycotic infections
were treated with 1.0% tolnaftate solution
or cream (chart #1). These clinical
trials and laboratory studies were con-
ducted in the out-patient department of
the University of Maryland Hospital and
the author's private practice. In vitro
studies showed tolnaftate to be ineffective
against Candida albicans and this finding
was confirmed by its therapeutic inefficacy
in the management of cutaneous lesions
due to this organism. Twenty-five patients
with tinea capitis due to microsporum
audouini and five with trichophyton ton-
surans infections of the scalp did not re-
spond to simple topical or occlusive dress-
ing therapy with tolnaftate solution. Nail
involvement did not respond. Interdigital
lesions due to trichophyton rubrum,
trichophyton mentagrophytes, and epi-
dermophyton floccosum cleared in 7 to
14 days following initiation of tolnaftate
therapy. In this type of lesion, griseo-
fulvin is ineffective. Palmar and plantar
lesions show a partial response to the
July. 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Tolnaftate Study
Chart *1
Organism
Total
No.
Treate
1%
Cream
i With
1%
Solution
Sites
Involved
Results
Good Poor
M. Furfur
56
24
32
Trunk 56
48
s
T. Rubruni
212
59
153
Hands \ 69
Feet /
Groins only 67
Trunk and
Extremities 30
Multiple
Sites 42
Nails only 4
54
67
30
42
15 palmar or
42 nails only
4
plantar
T. Mentagrophytes
11
2
9
Feet 3
Trunk and
Extremities 8
11
3M. Canis
6
4
2
Trunk, Fare 6
Extremities
6
M. Audouini
26
1
25
Glabrous skin 1
Scalp 25
1
25
T. Tonsurans
5
5
Glabrous skin 3
Scalp 2
3
E. Floccosum
5
3
2
Trunk 2
Groins 2
Feet 1
2
2
1
C. Albicans
2
2
Groins 2
2
local applications of the tolnaftate prepa-
rations, but when the solution or cream
was used alternately with a keratolytic
ointment such as Whitfield's or 10% sali-
cylic acid clearing was obtained. Ex-
cellent results were obtained in the treat-
ment of 48 of the 56 patients who had
tinea versicolor.
Trichophyton rubrum infections of the
trunk and extremities responded to the
topical applications of the tolnaftate prep-
arations, regardless of the duration of the
lesions. Interdigital eruptions due to the
same fungus also cleared promptly. Pa-
tients were relieved from itching in from
24 to 72 hours. There were no instances
of primary irritation or acquired hyper-
sensitivity.
Follow-up studies were performed on
90 patients with various superficial my-
cotic infections who had been success-
fully treated with the tolnaftate prepara-
tions from 4 to 26 months prior to the
recheck examinations (chart 2). Each
patient was examined for evidence of a
superficial fungus infection. Direct mic-
roscopic examinations and cultures were
made from the previously infected sites.
40
Ucl. M. No. S
ROBIXSOiW JR.—TOl.XAFTATE
Follow-up Study
Chart M2
Number
Shortest
Who
Longest
Shortest
Number
Time
Site
Retained
Observation
Observation
Who Had
Before
Organism
Involved
Remission
Period
Montlis
Period
Months
Relapses
Relapse
Muiilhs
T. Uulinim
Hands 1
Feet /
11
26
4
11
4
Groins
15
24
6
11
5
Trunk
4
24
4
3
4
Extremities ,
^lultiple 1
4
21
5
6
5
Sites /
E. Flocco5um
Feet
12
1
12
Trunk
1
24
—
M. Canis
Trunk, 1
Face I-
3
18
6
—
Extremities- J
T. Menta-
Feet
1
12
12
—
gropiiytes
Trunk, etc.
3
IS
4
—
M. Furfur
Trunk
2
13
4
14
4
Based on Follow-up of 90 Patients
Chart *3
Longest Period
Shortest Period of
Organism
Sites Involved
of Remission
Remission Without Relapse
T. Kubrum
Hands
Feet
26 Months
4 Months
Groins
24 Months
6 Months
Trunk and
24 Months
4 Months
Extremities
Multiple Sites
21 Months
5 Months
E. Floecosum
Feet
6 Months
6 Months
Trunk
24 Months
.M. Canis
Trunk
Face
Extremities
18 Months
T. Mentagrophytes
Feet
Trunk, etc.
12 Months
18 Months
Trunk
13 Months
4 Months
July. 1966
RULLETIX OF THE SCHOOL OF MEDICIXE. VXirERSITV OF .l/.-JAT/.J.W)
The relapse rate, calculated on the basis
of 90 patients, was as follows:
Infections due to T. rubrum 47.6%
E. floccosum 50.0%
T. mentagrophytes 0.0
M. canis 0.0
M. furfur 87.5%
The periods of remission (chart 3) be-
fore the redevelopment of subjective or
objective symptoms ranged from 4 to
26 months. In every instance of relapse
there was prompt response to retreatment
with tolnaftate solution or cream. The
relapse rate of cutaneous mycotic infec-
tions successfuly treated with tolnaftate
is approximately the same as the relapse
rate for those treated with griseofulvin.
Comment
Clinical and laboratory studies have
established the fact that tolnaftate, in
1.0% solution or cream, is an efficient
topical fungicidal agent which promptly
relieves subjective symptoms and clears
the lesions produced by the superficial
dermatophytes. Its sole value lies in the
treatment of mycotic infections and has
no beneficial effect on concurrent cutan-
eous eruptions The results of in vitro
studies are confirmed by clinical ex-
perience.
The preparations of tolnaftate have
produced no evidence of primary irrita-
tion or acquired contact hypersensitivity.
Animal studies revealed no evidence of
toxicity even on systemic administration
of exceptionally large doses.
The tolnaftate preparations, unlike
griseofulvin, will produce complete in-
volution of interdigital eruptions due to
fungi. In view of the fact that many erup-
tions simulate mycotic infections on the
feet, it is imperative to verify the diagnosis
of a fungus infection by the proper la-
boratory methods. Dyshidrosis, shoe der-
matitis, psoriasis, and eczematous erup-
tions are difficult to distinguish from
fungus infections by the most experienced
clinician. A clinical diagnosis alone is
never sufficient justification for specific
antifungal therapy.
The success obtained with tolnaftate
topical therapy eliminates the necessity
for systemic griseofulvin therapy except
in hair or nail infections.
The relapse rate of patients with super-
ficial mycotic infections successfully
treated with tolnaftate preparations, based
on a follow-up of 90 patients, is the same
as that obtained with systemic griseofulvin
treatment. Evidence of resistance to tol-
naftate did not develop. Those patients
who were successfully treated and sufl'ered
relapses responded to retreatment with the
same preparations. The 1 % solution and
the 1% cream are equally effective.
Summary and Conclusions
1 . Tolnaftate in 1 % solution or cream
applied topically is an effective antifungal
agent in the treatment of eruptions due
to Trichophyton rubrum. Trichophyton
mentagrophytes. Trichophyton tonsurans.
Epidermophyton floccosum, Microsporum
canis, Microsporum gypseum. Microspor-
um audouini and Microsporum furfur.
2. Evidence of primary irritation or
acquired contact sensitivity was not en-
countered in a series of 323 patients.
3. The preparation is ineffective in
the treatment of eruptions due to Candida
albicans or lesions in the scalp or nails
due to the dermatophytes.
4. Laboratory diagnosis is mandatory
because the drug is ineffective in the treat-
ment of cutaneous entities other than my-
cotic infections.
5. The relapse rate of tolnaftate treated
patients approximates the rate obtained
with griseofulvin treated patients. Evi-
dence of resistance did not occur and pa-
tients responded to retreatment with the
topical compounds.
42
Vol. 51. Xo. 3
MEDICAL SCHOOL SECTION
Dean's
LETTER
Dear Students, Members of the Alumni, and Friends of the Medical
School:
The Faculty Curriculum and Instruction Committee has been
engaged in a continuing study of our curriculum and the quality of
our instruction. As a part of this program about 100 faculty met
on June 13th to 16th of this year to study the recommendations of
the Committee for better integration of instruction and correlation of
curriculum subjects.
As a result of this study the faculty has decided to change the
curriculum starting with the entering class September 1966. The
change will consist in less emphasis on departmental teaching and
the utilization of faculty committees representing various departments
to present an integrated teaching of the subject involved. For ex-
ample, Neuro-anatomy will be presented from the structure and
functional basis by a team of faculty representing Neuro-anatomy,
Neuro-chemistry, Neuro-physiology, Neurology, Neuro-pathology and
Clinical Pathology.
This method of teaching should result in a more thorough and
stimulating program of instruction with less duplication of the sub-
jects presented.
Sincerely,
William S. Stone, M.D.
Dean
Julv, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNU'ERSITY OF MARYLAND
1886=1966
Dr. Ralph P. Truitt, former Professor of
Psychiatry in the School of Medicine, died
June 23, 1966. Dr. Truitt was 80.
A former executive secretary of the
Mental Hygiene Society of Maryland, he
headed the Community Fund Agency, a
national organization aimed to help the
mentally ill, particularly children. Dr. Truitt
was not only responsible for an emphasis on
psychiatric help for children and jail in-
mates, but also played a large part in
advancing psychiatry as a distinct medical
field. It was while he was active on Faculty
of the School of Medicine that Dr. Truitt
initiated the idea of a psychiatric institute
and laid the basic groundwork for its de-
velopment. Indeed, it is quite likely that
the institute would have developed under
his personal supervision had not World War
II interfered with its progress.
A native Eastern Shoreman, Dr. Truitt
was born in Snow Hill, Maryland, and was
graduated from Washington College in
Chestertown prior to his entering the School
of Medicine at the University of Maryland
from which he graduated in the Class of
1910. After an internship at the University
Hospital, he served as junior assistant
physician at the New Jersey State Hospital
in Trenton. In 1912, he returned to Balti-
more to head the Department of Psychiatry
at the City Hospitals. He later became resi-
dent psychiatrist at the Johns Hopkins
Hospital as a student of the late Adolf
Meyer. He then accepted a position as
clinical director of the Louisiana State
Hospital and became senior physician later
at the New Jersey State Hospital. During
World War I he served as a major in the
Medical Corps. After four years as director
of the Illinois Society for Mental Hygiene
and assistant professor of neurology and
psychiatry at the University of Illinois, he
became director of the Child Guidance
Clinic program of the Commonwealth Fund
of New York City.
In 1927 he joined the staff of the School
of Medicine and was associated with it for
more than 23 years prior to his retirement.
Dr. Paul D. Coleman Named
Associate Editor of Bulletin
Dr. Paul D. Coleman, Associate Professor
of Physiology at the School of Medicine, has
been named Associate Editor of the Bulletin
of the School of Medicine. Dr. Coleman
will assist in the preparation of special
scientific articles concerning the develop-
ment and highly important activities of a
professional nature taking place in the
School of Medicine. It is expected that he
will prepare a series of articles concerning
these important developments.
A graduate of Tufts University in the
class of 1948, Dr. Coleman received his
Doctor of Philosophy Degree at the Uni-
versity of Rochester in 1953. After a brief
period of service in the United States Army,
he served as assistant professor in the De-
partment of Physiology at Tufts University
and as an Associate at the Massachusetts
Institute of Technology, Computer Center.
He then was appointed a Special Fellow to
Johns Hopkins University School of Medi-
cine in the Departments of Anatomy and
Physiology, joining the Staff of the School
of Medicine of the University of Maryland
in 1962. Dr. Coleman has been active in
the development of educational programs
at the School of Medicine serving as a mem-
ber of the Curriculum Committee. He is
the author of more than 22 articles of a
professional nature dealing with basic
science research in physiology and par-
ticularly with reference to the physiology
of the nervous svstem.
\\,l 5L No. 3
faculty
NOTES
Department of Anatomy
Dr. A'ernon E. Krahl, Professor of
Anatoms. h.is just returned from Des
Moines, Iowa, where he gave a series of
guest lectures at the College of Osteopathic
Medicine and Surgery. Dr. Krahl gave
a convocation address to the Faculty and
student body of the College on the subject
"Neurovascular Control of the Peripheral
Pulmonary Circulation." He also presented
two seminars on the subjects: "Micro-
anatomy of the .'\irv\ays" and "Relationships
of Peripheral Pulmonary Vessels to the Lung
Parenchyma."
In June. Dr. Krahl attended the Fifth An-
nual Pulmonary Workshop at the Webb-
Waring Institute of the University of Colo-
rado Medical Center. There he presented
his new motion picture film on living ciliated
epithelium and a demonstration of the
preparation and microscopic observation of
ciliated epithelium in the gills of Venus
mercenaria. He then attended the Ninth
Annual Conference on Research in Emphy-
sema at Aspen, Colorado, where by invi-
tation he presented a paper entitled
"Mechanisms Controlling the Peripheral
Circulation of the Lung with some Clinical
Correlations." Later, Dr. Krahl presented
his film on ciliary activity.
From June 26th to July 2nd, 1966, he
attended the Fourth European Conference
on Microcirculation at Cambridge, England,
where he presented a paper entitled "Further
Studies on Perfusion of Pulmonary Alveolar
Capillaries: the Effects of Exercise, Vagal
Stimulation and of Adrenergic and Chol-
inergic Agents."'
Dr. Krahl is emminently known for his
basic studies in the finer anatomy and physi-
ology of the lung.
Department of Medicine
Dr. William S. Spicer, Jr., Associate Pro-
fessor of Medicine and head of the Division
of Pulmonary Diseases, has been nominated
to the Maryland State Board of Health. Dr.
Spicer replaces Dr. J. Edmund Bradley who
resigned following his retirement from the
School of Medicine.
Department of Neurology
Dr. Richard F. Mayer, Associate Pro-
fessor of Neurology, has received a grant
from the Multiple Sclerosis Foundation to
support his study of the manner in which
multiple sclerosis and other related diseases
damage the central nervous system.
Department of Pediatrics
Dr. Thomas Christensen, resident in pedi-
atrics at the University Hospital during the
1930"s and until recently a private prac-
titioner in Prince Georges County, Mary-
land, died on May 3, 1966.
Department of Radiology
Dr. Fernando G. Bloedorn, Professor of
Radiology at the School of Medicine,
recently presented a paper entitled "Pre-
operative Irradiation" at a meeting of the
Club International de Telecobaltherapie at
Modena, Italy.
Dr. Gerald Wagger Appointed
Assistant Director of Committee
on Post-Graduate Courses
Dr. E. T. Lisansky, Chairman and Director
of the Committee on Post-Graduate Courses,
has announced the appointment of Dr.
Gerald Wagger as his Assistant Director.
Dr. Wagger will assume his responsibility
as a part-time venture and will continue his
work in the Department of Medicine as an
July, 1966
Bl'LLETIN OF THE SCHOOL OF MEDICINE. UXIVERSITY OF MARYLAXD
Assistant Professor in the division of Gastro-
enterology.
A graduate of the University of North
Carolina School of Medicine, Dr. Wagger
completed his residency at the University
Hospital in 1965 and has served as an In-
structor in Medicine in the Division of
Gastroenterology for the past year. The
Post-Graduate Committee will now be in
a position to implement certain programs
that were heretofore unfeasible because of
inadequate personnel.
Faculty Participate in 1966 Spring
Scientific Assembly of
Maryland and D, C. Academies
of General Pi'actice
A number of Faculty members were
active on the program of the Academy of
General Practice Annual Meeting. These
include Dr. Cyrus L. Blanchard who pre-
sented a paper entitled "Inflammation of
the Ear. Nose and Throat," Dr. Keith C.
Morgan spoke on "Acute and Chronic In-
flammation of the Bronchial Tree," Dr.
Arthur L. Haskins delivered a paper on
"Female Pelvic Inflammatory Disease" and
Dr. Robert T. Singleton, Director of the
Cardio-Vascular Laboratory, spoke on "In-
flammatory Conditions of the Heart and
Vascular System."
Dr. John D. Young, Professor and head
of the Department of Urology, spoke on
"Inflammatory Conditions of the Genito-
urinary System," while Dr. Harry M. Robin-
son, Professor and head of the Department
of Dermatology, spoke on "Common In-
flammatory Disease of the Skin." This was
supported by Dr. Merrill J. Snyder of the
Department of Medicine who spoke on
"Staphylococcal Septicemias." Dr. George
N. Austin, head of the Department of Ortho-
pedics, spoke on "Inflammatory Diseases of
Bone and Joints." Dr. Samuel P. Bessman,
Professor of Biochemistry, spoke on the sub-
ject "Diabetes Mellitus and Oral Hypogly-
cemic Agents."
f'o/. ."il. \o. 3
Publicalioiis of Slatt" of St-liool of Mojlirine 1964-1965
DEPARTMENT OF ANATOMY
Burns, T. A., ami Crispens, C. G., Jr. : Electron
Microscope Investigation of Lactic De-
lij'drogenasc Agent. Xaliirc (London), 201:
1302, 1964.
Crispe.vs, C. G., Jr. : Preliminary Studies on
In Utcro Transmission of the Lactic De-
hydrogenase .-Kgent, Aiiat. Rcc, 149: 511, 1964
(abstract).
Crispexs. C. G., Jr.: .\ Cage for L'se in Foster
Nursing Studies with Mice. Aiiicr. J. Clin.
Path.. 42: 332, 1964.
Crispexs, C. G., Jr.: Mouse Plasma Lactic
Dehydrogenase Elevation : Evidence for Two
Particles, Virology, 24: S01-S02, 1964.
Crispens, C. G., Jr. : The Lactic Dehydrogenase
Agent: Its Possible Implications for the
Virologist and Oncologist. Bull. Sch. Med.
Univ. Maryland. 49: vii, 1964 (abstract).
Crispexs, C. G., Jr. : Outline of Histology by
Gerrit Bevelander, C. V. Mosby Co., St.
Louis, 5th Ed., 332 pp., 1963. Quart. Rev.
Biol., 39: 412, 1964 (book review).
Crispexs, C. G., Jr.. and Buk.xs. T. A. : Electron
Microscope Investigation of Lactic De-
hydrogenase Agent, Xature (London), 204:
1302, 1964.
Kr.\hl, V. E. : Anatomy of Mammalian Lung,
Handbook of Physiology, Section 3, Respira-
tion. 1: 213-284, 1964.
Kr.^hl, V. E. : The Lung as a Target Organ
in Thromboembolism : Pulmonary Embolic
Diseases, edited by Sasahara, Grune and
Stratton, New York, pp. 13-22, 1965.
Krahl. V. E. : Living Pulmonary Histology,
Aging Of The Lung, edited by Gander and
Moyer, Grune and Stratton, New York, pp.
55-60, 1965.
Kr.\hl. V. E. : A Classroom Demonstration of
the Mechanism of the Larj'n.x, Turto.v Xczcs,
43: 20-22, 1965.
Krahl. \^. E. : In Vivo Microscopy of the
Rabbit's Lung, Bibl. Anat., 4: 400-410, 1964.
Krahl, V. E. : Anatomy of Mammalian Lung,
Handbook of Physiology. Section 3, Respira-
tion. 1: 213-284, 1964.
Kr.\hl, V. E. : The Lung as a Target Organ
in Thromboembolism. Pulmonary, 1965.
DKl'AUTMKNT Ol' ANESTHESIOLOGY
.\twiio[i, J. .\l., and Hklrich, M. : Modification
of .Scrnyl .\ncsthesia with Halopcridol,
Aneslh. Analg. (Cleveland), 43: 471, 1964.
.\tw(ioi). J. M. : Respiratory Obstruction Dur-
ing Bronchography, Anesthesiology. 26: 234,
1965.
Baker, L. R. : Nonrebreathing Assembly,
Anesthesiology, 26: 229, 1965.
Bessmax, S. p., Helrich, M., Mc.Aslax. T. C,
and Skolxik. S. : .A Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology. 25: 711, 1964.
Evers, J. L., Lowe, H. J., Hax, Y'. H., Gold,
M. I., and Helrich, M. : The Central and
Peripheral Effects of Halothane Upon Respi-
ration in Man, Anesthesiology, 26: 249, 1965.
Gold, M. I., and Helrich. M. : Response to
Circulatory Stress in Man Following Anal-
gesic Drugs. Acta Aiiesfh. Scand.. 15: 97,
1964.
Gold, M. I., and Helrich, M. : Circulatory Re-
sponse to Tilting Following Methotrime-
prazine and Morphine in Man, Anesthesi-
ology, 25: 622, 1964.
Gold. M. I., Evers, J. L., Lowe, H. J., Han,
Y. H., and Helrich, M. : The Central and
Peripheral Effects of Halothane Upon Respi-
ration in Man, Anesthesiology, 26: 249, 1965.
Gold, M. I., and Helrich. M. : Pulmonary
Mechanics During General Anesthesia in
Normal Man, Fed. Proc. 24: 268, 1965.
Gold. AI. I., and Helrich. M. : Dynamic
Pulmonary Compliance During .Anesthesia,
Anesthesiology, 26: 281, 1965.
Gold, M. I. : The Impact of Tranquilizers
on Anesthesia, Audio-Digest, Anesthesiology,
6: lOA, 1964.
Gold, M. I. : Tranquilizers in the Surgical
Patient, Surgery, 56: 1027, 1964.
Gold, M. : The Hazards of Anesthetizing Asth-
matic Patients, Allerg. Patient, 6: 1, 1965.
Gold, M. I. : Anesthesia and Asthma, E.E.N. T.
Digest. In press.
Gold, M. I.: Respiratory Obstruction, Anes-
thesiology. In press.
Gold, M. I. : Tranquilizers and Other Central
Depressants, Clin. Med. In press.
/»/v, 1966
BULLETIX OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Gold, M. I., and Helrich. M. : Mechanics of
Breathing During Anesthesia. II. The In-
fluence of Airway Adequacy, Anesthesiology.
In press.
Han, Y. H., Lowe, H. J., Evers, J. L., Gold,
M. I., and Helrich, M. : The Central and
Peripheral EiTects of Halothane Upon Respi-
ration in Man, Anesthesiology, 26: 249, 1965.
Helrich, M., and Gold, M. I. : Response to
Circulatory Stress in Man Following Anal-
gesic Drugs, Acta Anesth. Scand., 15: 97,
1964.
Helrich, AL, and Gold, M. I. : Circulatory
Response to Tilting Following Metho-
trimeprazine and Morphine in Man, Anes-
thesiology, 25: 622, 1964.
Helrich, M., McAslan, T. C, Skolnik, S.,
and Bessman, S. P. : A Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 711, 1964.
Helrich, M., and Atwood, J. M. : Modification
of Sernyl Anesthesia With Haloperidol,
Anesth. Analg. (Cleveland), 43: 471, 1964.
Helrich, M., Gold, M. L, Evers, J. L., Lowe,
H. J., Han, Y. H. : The Central and Peri-
pheral Effects of Halothane Upon Respira-
tion in Man, Anesthesiology, 26: 249, 1965.
Helrich. M., Gold, M. I. : Pulmonary
Mechanics During General Anesthesia in
Normal Man, Fed. Proc., 24: 268, 1965.
Helrich, M., and Gold, M. I. : Dynamic Pulmo-
nary Compliance During Anesthesia, Anes-
thesiology, 26: 281, 1965.
Helrich, M., and Gold, M. I. : Mechanics of
Breathing During Anesthesia. II. The In-
fluence of Airway Adequacy, Anesthesiology.
In press.
Lowe, H. J., Hax, Y. H., Evers, J. L., Gold.
M. I., and Helrich. M. : The Central and
Peripheral Effects of Halothane LTpon Respi-
ration in Man, Anesthesiology, 26: 249, 1965.
McAsLAN, T. C. Helrich, M., Skolnik, S.,
and Bessman, S. P. : A Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 711, 1964.
Skolnik, S., Helrich, M., McAslan, T. C,
and Bessman, S. P. : A Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 711, 1964.
DEPARTMENT OF BIOPHYSICS
Awad, M. Z., and Mullins, L. J. : The Control
of the Membrane Potential of Muscle Fibers
by the Sodium Pump, /. Gen. Physiol., 48:
761-765, 1965.
Barr, Charles E. : Sodium Regulation in
Nitella, J. Gen. Physiol. In press, 1965.
Brinley, F. J., Jr., and Mullins, L. J. : Ion
Fluxes and Transference Number in Squid
Axons, /. NeurophysioL, 28: 526-544, 1965.
Frumexto, a. S., and Mullins, L. J.: Po-
tassium-free Effect in Squid Axons, A'ature,
204: 1312-1313, 1964.
Henderson, E. G., and Sjodin, R. A. : Asym-
metric Properties of the Muscle Cell Mem-
brane Deduced from the Effects of Rubidium
Ions on Potassium Movements. Presented at
Biophysical Society Meeting, San Francisco,
February, 1965.
Hybl, a., Rundle, R. E., and Williams, D. E. :
The Crystal and Molecular Structure of
Cyclohexaamylose — Potassium Acetate Com-
plex, /. Amer. Cheni. Soc. In press, 1965.
Moore, R. D., and Zarrow, M. X. : Contraction
of the Rabbit Mammary Strip in Vitro in
Response to Oxytocin, Acta Endocr., (Koben-
havn), 48: 186, 1965.
Mullins, L. J., and Frumento, A. S. : Po-
tassium-free Effect in Squid Axons, Nature,
204: 1312-1313, 1964.
Mullins, L. J., and Awad, M. Z. : The Con-
trol of the Membrane Potential of Muscle
Fibers by the Sodium Pump, /. Gen. Phxsiol.,
48: 761-775, 1965.
Mullins, L. J., and Brinley, F. J., Jr. : Ion
Fluxes and Transference Number in Squid
Axons, J. NeurophysioL, 28: 526-544, 1965.
Mullins, L. J. (Ed.) : A Conference on Newer
Properties of Perfused Squid Axons, /. Gen.
Physiol., 48: 1-92, (Part 2), 1965.
RuNDLE, R. E., Hy-bl, a., and Williams, D. E. :
The Crystal and Molecular Structure of
Cyclohexaamylose — Potassium Acetate Com-
plex, /. Amer. Client. Soc, 1965. In press.
SjODiN, R. A. : The Potassium Flux Ratio in
Skeletal Muscle as a Test for Independent
Ion Movement, /. Gen. Physiol., 48: 777-796,
1965.
Sjodin, R. A. : Discussion Report : Newer
Properties of Perfused Squid Axons, /. Gen.
Physiol., 48: 83-92, (Part 2), 1965.
SjoDiN, R. A., and Henderson, E. G. : Asym-
metric Properties of the Muscle Cell Mem-
brane Deduced from the Effects of Rubidium
Ions on Potassium Movements. Presented at
Vol. 51. No. 3
MEinCAL SCHOOL SECTIOX
Biophysical Socifty Meeting, San Francisco,
February, 1965.
Williams, D. E., Rlxdle, R. E., and Hybl.
A. : The Crystal and Molecular Structure of
Cyclohexaamylose — Potassium Acetate Com-
plex, /. Amcr. Chciii. Soc, 1965. In press.
Z.\RR0\v, M. X., and Moore, R. D. : Contraction
of the Rabbit Mammary Strip in Vitro in
Response to Oxytocin, Acln Endcr. ( Kobcn-
havn), 48: 186, 1965.
DEPARTMENT OF INTERNATIONAL
MEDICINE
Barnett. H. C, and Gang.\R0sa, E. J.: Ob-
servations On the Toxicity of Dichlovos
(DDX'P) Vapors to Humans Following Pro-
longed Exposure, J.A.M.A. In press.
Gangarosa, E. J., and Barnett, H. C. : Ob-
servations on the Toxicity of Dichlovos
(DDVP) Vapors to Humans Following Pro-
longed Exposure, J.A.M.A. In press.
Gorten, at K., and Hefner, W. R. : Iron
Balances in Small Premature Infants,
Southcni Med. J., 57: 1462, 1964.
Cortex. M. K., Hepxer, \V. R., and Workman,
J. B. ; Iron Metabolism in Premature Infants
1. Absorption and Utilization of Iron as
Measured by Isotope Studies, Blood, 23: 551,
1964 (abstract).
Hepxer, W. R., and Gortex^ M. K. : Iron Bal-
ances in Small Premature Infants, Southern
Med. J.. 57: 1462, 1964.
Hefner, W. R. : Care of the Premature, Curr.
Therapy, 1965.
Hefner, W. R., and Gorten, M. K., and Work-
man, J. B. : Iron Metabolism in Premature
Infants I. Absorption and Utilization of Iron
as Aleasured by Isotope Studies, Blood, 23:
551, 1964 (abstract).
Hoogstraal, H., and McCarthy, V. : Subgenus
Persicargas (Ixodidae, Argasidae, Argas)
2. A. (P) abdussalami, n.sp.. Associated with
Birds on Trees and Buildings near Lahore,
Pakistan, J. Parasit. In press.
Hoogstraal, H., and McCarthy, Y. : The
Hosts and Distribution of Haemaphysalis
(Herpetobia) Kashmireiisis Hoogstraal and
Varma, /. Parasit. In press.
Klimt, C, and Meinert, C. : A Population
Based Study of the Familial Pattern of Re-
ported Diabetes, /. Amer. Diet. Ass. Sub-
mitted.
Klimt, C, and Meinert, C. : Testing the Single-
Gene .Autosomal Recessive Hypothesis in
Proband Studies of Diabetes Mcllitus, J.
.liner. Diet. Ass. Submitted.
McCarthy, V., and Hoogstraal, H. : Subgenus
Persicargas (Ixodidae, Argasidae, Arga.^) 2.
A. (P) abdussalami, n.sp.. Associated with
Wild Birds on Trees and Buildings near
Lahore, Pakistan, /. Parasit. In press.
McCarthy, V., and Hoogstraal, H. : The Hosts
and Distribution of Haemaphysalis (Herpe-
tobia) Kashmirensis Hoogstraal and Varma,
J . Parasit. In press.
Meinert, C, and Klimt, C. : A Population
Based Study of the Familial Pattern of Re--
ported Diabetes, /. Amer. Diet. Ass. Sub-
mitted.
Meinert, C, and Klimt, C. : Testing the Single
Gene Autosomal Recessive Hypothesis in Pro-
band Studies of Diabetes Mellitus, /. Amer.
Diet. Ass. Submitted.
Tariq, Z. K. : A Preliminary Report of the.
Mosquitoes in the Gilgit Agency Area,
Pakistan J. Health. In press.
Workman, J. B., Gorten, M. K., and Hepner,
W. R. : Iron Metabolism in Premature
Infants I. Absorption and Utilization of Iron
as Measured by Isotope Studies, Blood, 23:
551, 1964 (abstract).
DEPARTMENT OF MEDICINE
Greisman, Sheldon E., Hornick, R. B., and
Woodward, T. E. : The Role of Endotoxin
during Typhoid Fever and Tularemia in Man.
III. Hyperreactivity to Endotoxin during
Infection, /. Clin. Invest. 43: 1747, 1964. .
Greisman, Sheldon E., and A\'oodward, W. E. :
Mechanisms of Endotoxin Tolerance. III.
The Refractory State during Continuous In-
fusions of Endotoxin, /. E.rp. Med., 121:
911, 1965.
Hornick, R. B., Greisman, Sheldon E., and
Woodward, T. E. : The Role of Endotoxin
during Typhoid Fever and Tularemia in Man.
III. Hyperreactivity to Endotoxin during In-
fection, /. Clin, hives., 43: 1747, 1964.
Morrison, Samuel : Editorial : The Hospital
Trilemma, Maryland Med. J., 12: 435, 1963.
Morrison, Samuel : On Dignity in the Medical
Profession, Curr. Med. Dig., 30: 3, 1963.
Morrison, Samuel : Editorial : Reflections of a
Committee Chairman, Maryland Med. J., 12:
537, 1963. . . ■
Julv, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Morrison, Samuel : Editorial : Ethics, Mary-
land Med. ]., 13: 145, 1964.
Morrison^ Samuel : Editorial : How Far, Cata-
line?, Maryland Med. J., 13: 21, 1964.
Morrison, Samuel: Doctor and Patient, The
Morning Sun, January 11, 1965.
Morrison, Samuel : Patient-Doctor Goals
Stressed, The News American, January 13,
1965.
Woodward. T. E., Hornick. R. B., and Greis-
man, Sheldon, E. : The Role of Endotoxin
during Typhoid Fever and Tularemia in Man.
III. Hyperreactivity to Endotoxin During In-
fection, /. Clin. Invest., 43: 1747, 1964.
Woodward, W. E., and Greisman, Sheldon, E. :
Mechanisms of Endoto.xin Tolerance. III. The
Refractory State during Continuous In-
fusions of Endotoxin, /. E.i-p. Med., 121: 911,
1965.
Division of Arthritis
Bhatavadekar, D., Rothschild, H., Schroed-
ER, W. C, Heuckenkamp, p. U., Onodera,
S., EwALD, R. W., Schubart, a. F., and
PuLLEN, p. : Changes of Titer of Rheumatoid
Factor, Termolabile Inhibitor, and Serum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Bhatavadekar, D., Rothschild, H. J.,
Schroeder, W. C, Ewald, R. W., Schubart,
A. F., and Pullen, P. : Serum Complement
Levels in Rheumatoid Arthritis. A Longi-
tudinal Study of 43 Cases with Correlation of
Clinical and Serological Data Including
Rheumatoid Factor and Thermolabile In-
hibitor of the F-11 L. P. Test, Ami. Rheum.
Dis., 1965. In press.
Ewald, R. W., Hornick, R. B., Schubart,
A. F., Schroeder, W. C, Myerburg, R. J.,
Goodman, J. S., and Woodward, T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever. A
Longitudinal Study of the Disease Including
the Incubation Period and the Phase of Re-
covery Following Treatment with Chlora-
phenicol, /. Imtnun., 93: 387, 1964.
Ewald, R. W., Schubart, A. F., Onodera, S.,
Heuckenkamp, P. U., Schroeder, W. C,
Rothschild, H., Bhatavadekar, D., and
Pullen, P. : Changes of Titer of Rheuma-
toid Factor, Termolabile Inhibitor, and Serum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Ewald, R. W., and Schubart, A. F. : Kinetic
Studies of Serum Complement Components
Creating Inhibition of the Agglutination Ac-
tivating Activity of the Rheumatoid Factor,
Arthritis Rheum., 8: 467, 1965.
Ewald, R. W., and Schubart, A. F. : Studies
Concerning the Possible Identity of Watson's
Antiglobulin and the First Component of
Complement in the Latex Fixation Test,
Arthritis Rheum., 8: 442, 1965.
Ewald, R. W., Schubart, A. F., Schroeder,
W. C, Rothschild, H. J., Bhatavadekar,
D., and Pullen, P. : Serum Complement
Levels in Rheumatoid Arthritis. A Longi-
tudinal Study of 43 Cases with Correlation of
Clinical and Serological Data Including
Rheumatoid Factor and Thermolabile In-
hibitor of the F-11 L. P. Test, Ann. Rheum.
Dis., 1965. In press.
Ewald, R. W., Onodera, S., Heuckenkamp,
P. U., and Schubart, A. F. : Incidence of
Anti-nuclear Factors in Patients with Rheum-
atoid .'Krthritis. A Comparison of Comple-
ment Fixation and Latex Particle Agglutina-
tion Techniques. Submitted for publication in
Ann. Rheum. Dis.
Goodman, J. S., Myerburg, R. J., Schroeder,
W. C, Ewald, R. W., Hornick, R. B., Schu-
bart, A. F., and Woodward, T. E. : Changes
of Serum Complement and Properdin Levels
in Experimental Typhoid Fever. A Longi-
tudinal Study of the Disease Including the
Incubation Period and the Phase of Re-
covery Following Treatment with Chlora-
phenicol, /. Immun., 93: 387, 1964.
Heuckenkamp, P. U., Onodera, S., Ewald.
R. W., Schubart, A. F., Schroeder, W. C,
Rothschild, H., Bhatavadekar, D., and
Pullen, P. : Changes of Titer of Rheumatoid
Factor, Termolabile Inhibitor, and Serum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Heuckenkamp, P. U., Ewald, R. W., Ono-
dera, S., and Schubart, A. F. : Incidence of
Anti-nuclear Factors in Patients with Rheum-
atoid Arthritis. A Comparison of Comple-
ment Fixation and Latex Particle Agglutina-
tion Techniques. Submitted for publication in
Ann. Rheum. Dis.
Hornick, R. B., Schubart, A. F., Ewald.
R. W., Schroeder, W. C, Myerburg. R. J.,
Goodman, J. S., and Woodward, T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever. A
Longitudinal Study of the Disease Including
J'o/. >1. No.
MEDICAL SCHOOL SECTIOS'
the Inciihatioii Pi-riod and the Phase of Re-
covery Following Treatment witli Chlora-
phenicol, /. Immiin.. 93: 387, 1964.
MVERBURG, R. J., SCHROEDER, W. C, EwALD,
R. \V., HORNICK, R. B., SCHUBART, A. F.,
Goodman. J. S., and Woodward. T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever. A
Longitudinal Study of the Disease Including
the Incubation Period and the Phase of Re-
covery Following Treatment with Chlora-
phenicol. /. Immun.. 93: 387, 1964.
OXODERA. S., E\\ Al.l). R. W'.. ScHUBART, A. F.,
Hevckk.nkamp. p. L'., Schroeder, W. C,
RoTHSt'iiH.u. H.. Bhatavadekar. D., and
PuLLF.x. p.: Changes of Titer of Rheuma-
toid Factor, Termolabile Inhibitor, and Scrum
Complement During the Court of Rheumatoid
.Arthritis, Arthritis Rheum.. 8: 466, 196S.
Oxodera. S., Ewald, R. W. Heuckenkamp,
P. L'., and ScnuBART. .\. F. : Incidence of
.Anti-nuclear Factors in Patients with Rheum-
atoid .Arthritis. .A Comparison of Complement
Fixation and Latex Particle Agglutination
Techniques. Submitted tor publication in
Aitii. Rheum. Dis.
PvLLEX. P., Bhatavadekar, D., Rothschild,
H., Schroeder. W. C, Heuckenkamp, P. U.,
Oxodera, S., Ewald, R. W., Schubart,
-A. F. : Changes of Titer of Rheumatoid
Factor, Termolabile Inhibitor, and Serum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Pullen, p., Bhatavadekar, D., Rothschild,
H. J., Schroeder. W. C, Ewald, R. W.,
ScHL-BART, A. F. : Serum Complement Levels
in Rheumatoid .Arthritis. A Longitudinal
Study of 43 Cases with Correlation of Clinical
and Serological Data Including Rheumatoid
Factor and Thermolabile Inhibitor of the
F-11 L. P. Test, Ann. Rheum. Dis., 1965.
In press.
Rothschild, H., Schroeder, W. C, Heucken-
KAMP, P. U., Oxodera. S., Ewald. R. W.,
Schubart, A. F., Bhatavadekar. D., and
PuLLEN, P. : Changes of Titer of Rheuma-
toid Factor, Termolabile Inhibitor, and Serum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Rothschild, H. J., Schroeder, W. C. Ewald,
R. \V., Schubart, A. F., Bhatavadekar. D.,
and PuLLE.x, P. : Serum Complement Levels
in Rheumatoid Arthritis. A Longitudinal
Study of 43 Cases with Correlation of Clinical
and Serological Data Including Rheuni;itoi<l
Factor and Thermolabile Inhibitor of the
F-11 L. P. Test, Ami. Rheum. Dis., 1965.
In press.
Schroeder. W. C, Ewald. R. W., Hornick,
R. B., Schubart. .A. F., Mverburo. R. J.,
Goodman, J. S., and Woodward. T. E. :
Changes of Serum Complement and Proper-
din Levels in Experimental Typhoid Fever.
.A Longitudinal Study of the Disease Includ-
ing the Incubation Period and the Phase of
Recovery Following Treatment with Chlora-
phenicol, J. Immun., 93: 387, 1964.
Schroeder. W. C, Heuckenkamp, P. U., O.xo-
dera. S., Ewald, R. W., Schubart, A. F.,
Roth.schild. H., Bhatavadekar. D., and
Pullen, P. : Changes of Titer of Rheumatoid
Factor, Termolabile Inhibitor, and Scrum
Complement During the Course of Rheuma-
toid Arthritis, Arthritis Rheum., 8: 466, 1965.
Schroeder, W. C, Ewald, R. W., Schubart,
\. F., Rothschild, H. J., Bhatavadekar, D.,
and Pullen, P. : Serum Complement Levels
in Rheumatoid Arthritis. .A Longitudinal
Study of 43 Cases with Correlation of Clinical
and Serological Data Including Rheumatoid
Factor and Thermolabile Inhibitor of the
F-11 L. P. Test, Ann. Rheum. Dis., 1965.
In press.
Schubart, A. F., Heuckexkamp, P. U.,
Ewald, R. W., Ondera, S. : Incidence of
Anti-nuclear Factors in Patients with Rheum-
atoid Arthritis. A Comparison of Complement
Fixation and Latex Particle Agglutination
Techniques. Submitted for publication in
Ann. Rheum. Dis.
Schubart, A. F., Hornick, R. B., Ewald,
R. W., Schroeder, W. C, Myerburg, R. J.,
Goodman, J. S., and Woodward. T. E. :
Changes of Serum Complement and Proper-
din Levels in Experimental Typhoid Fever.
A Longitudinal Study of the Disease Includ-
ing the Incubation Period and the Phase
of Recovery Following Treatment with
Chloraphenicol, /. Immun., 93: 387, 1964.
Schubart, A. F., Ewald, R. W., Onodera. S.,
Heuckenkamp. P. U., Schroeder, W. C,
Rothschild, H., Bhat.wadekar, D., and
Pullen, P. : Changes of Titer of Rheuma-
toid Factor, Thermolabile Inhibitor, and
Serum Complement During the Course of
Rlieumatoid Arthritis, Arthritis Rheum., 8:
466, 1965.
Schubart, A. F., and Ewald, R. W. : Kinetic
/»/v, 1966
BULLETIX OF THE SCHOOL OF MEDICINE. UKU'ERSITY OF MARYLAXD
Studies of Serum Complement Components
Creating Inhibition of the Agglutination
Activating Activity of the Rheumatoid Factor,
Arthritis Rheum., 8: 467, 1965.
ScHUBART, A. F., and Ewald, R. W. : Studies
Concerning the Possible Identity of Watson's
Antiglobulin and the First Component of
Complement in the Latex Fixation Test,
Arthritis Rheum., 8: 442, 1965.
ScHUBART. A. F., Ewald, R. W., Schroeder,
W. C, Rothschild, H. J., Bhatavadekar,
D., and Pullen, P. : Serum Complement
Levels in Rheumatoid Arthritis. A Longi-
tudinal Study of 43 Cases with Correlation of
Clinical and Serological Data Including
Rheumatoid Factor and Thermolabile In-
hibitor of the F-11 L. P. Test, Ann. Rheum.
Dis., 1965. In press.
Woodward, T. E., Goodman, J. S., Myerburg,
R. J., Schroeder, W. C, Ewald, R. W.,
HoRNicK, R. B., and Schubart. A. F. :
Changes of Serum Complement and Proper-
din Levels in E.xperimental Typhoid Fever.
A Longitudinal Study of the Disease Includ-
ing the Incubation Period and the Phase of
Recovery Following Treatment with Chlora-
phenicol, /. Immun.. 93: 387, 1964.
Division of Cardiology
AxTLiTZ. A. M., and Dembo, D. H. : Chloridia-
zeporide Therapy in Angina Pectoris. A
Double Blind Study, Angiology, 15: 207, 1964.
Antlitz, a. M., and Boudreau, R. : Congenital
Isolated Mitral Insufficiency, Dis. Chest, 46:
Aug., 1964.
Baker, E. L., Serpick, A. A., and Woodward,
T. E. : Motor System Disease. Review and
Discussion of a Case Presenting with Alveo-
lar Hypoventilation, Arch. Intern. Med., 115:
192, 1965.
Boudreau, R., and Antlitz, A. AI. : Congenital
Isolated Mitral Insufficiency, Dis. Chest, 46:
Aug., 1964.
Cowley, R. A., and Dembo, D. H. : Left Atrial
Thrombosis with Ball Valve Action. Report
of a Case with Successful Surgical Removal,
Arch. Intern. Med., 114: 139, 1964.
Dembo, D. H., and Antlitz, A. M. : Chloridia-
zeporide Therapy in Angina Pectoris. A
Double Blind Study, Angiology, 15: 207, 1964.
Dembo, D. H., and Singleton, R. T. : Kryp-
ton-8S in the Detection of Left to Right
Shunts, Circulation. In press.
Dembo, D. H., Scherlis, L., and Jude, J.:
Definitive Therapy in Cardiopulmonary
Resuscitation, Amer. Heart J., 1965.
Dembo, D. H., Scherlis, L., Jude, J., and
Farr, M. : The Nurses' Role in Cardiopulmo-
nary Resuscitation, Amer. Heart J. In press.
Dembo, D. H., and Cowley, R. A. : Left Atrial
Tronibosis with Ball Valve Action. Report of
a Case with Successful Surgical Removal,
Arch. Intern. Med., 114: 139, 1964.
Farr, M., Jude. J., Scherlis, L., and Dembo,
D. H. : The Nurses' Role in Cardiopulmonary
Resuscitation, Amer. Heart J. In press.
Farr, M., Jude, J., and Scherlis, L. : Emer-
gency Measures in Cardiopulmonary Resusci-
tation, Amer. Heart J., 1965.
Jude, J., Scherlis, L., and Dembo. D. H. :
Definitive Therapy in Cardiopulmonary Re-
suscitation, Amer. Heart J., 1965.
Jude, J., Scherlis, L., Dembo, D. H., and
Farr, M. : The Nurses' Role in Cardiopulmo-
nary Resuscitation, Amer. Heart J. In press.
Jude, J., Scherlis, L., and Farr, M. : Emer-
gency Measures in Cardiopulmonary Resusci-
tation, Amer. Heart J., 1965.
Lee, y. C, Scherlis, L., and Singleton, R. T. :
Mitral Stenosis. Hemodynamic, Electrocardio-
graphic and Vectorcardiographic Studies,
Amer. Heart J., 69: 559, 1965.
Lee. Y. C, Papadopoulos, C, and Scherlis, L. :
Isolated Ventricular Septal Defect. Hemody-
namic, Electrocardiographic and \'ector-
cardiographic Studies, Amer. J. Cardiol. In
press.
P.\p.\DOPOULos, C, Lee, Y. C, and Scherlis, L. :
Isolated Ventricular Septal Defect. Hemody-
namic, Electrocardiographic and Vectorcardio-
graphic Studies, Amer. J. Cardiol. In press.
RuBENSTEiN, H. J., and W^eaver, K. : Monozy-
gotic Twins Concordant for an Interventricu-
lar Septal Defect, Amer. J. Cardiol, 15: 386,
1965.
Scherlis. L., Lee, Y. C, and Singleton. R. T. :
Mitral Stenosis. Hemodynamic, Electrocardio-
graphic and Vectorcardiographic Studies,
Amer. Heart J., 69: 559, 1965.
Scherlis, L., Dembo, D. H., and Jude, J.:
Definitive Therapy in Cardiopulmonary Re-
suscitation, Amer. Heart J.. 1965.
Scherlis, L., Dembo, D. H., Jude, J., and
Farr, M. : The Nurses' Role in Cardiopulmo-
nary Resuscitation, Amer. Heart J. In press.
Scherlis, L., Jude, J., and Farr. M. : Emer-
Vol. ^1. Xo 3
MEDlC.tL SCHOOL SF.CTIOX
gency Measures in Cardiopulmonary Resusci-
tation, Amcr. Heart J., 1965.
ScHERLis. L.. Lee. V. C, and PAPAnopoui-os, C. :
Isolated \'entricular Septa! Defect. Hemody-
namic. Electrocardiographic and Vectorcardio-
grapliic Studies, Amcr. J. Cardiol. In press.
ScHERLis. L. : Book review: Circulation and
Respiration. Cur. Med. Dig., 32: 111, 1965.
ScHERLis. S. : Stress, Trauma, and Heart Dis-
ease. Chapter in Cyclopedia of Medicine, F. A.
Davis Co., 1965.
Serpick, .\. A., Baker, E. L., and Woodward.
T. E. : Motor System Disease. Review and
Discussion of a Case Presenting with Alveolar
Hypoventilation, Arch. Intent. Med.. 115:
192, 1965.
SixGLETOx. R. T., ScHERLis, L., and Lee. Y. C. :
Mitral Stenosis. Hemodynamic, Electrocardio-
graphic and Vectorcardiographic Studies,
Amcr. Heart J., 69: 559, 1965.
Singleton, R. T., and Dembo. D. H. : Krypton-
85 in the Detection of Left to Right Shunts,
Circulation. In press.
^^'E.\VER. K., and Rubexsteix, H. J.: Monozy-
gotic Twins Concordant for an Interventricu-
lar Septal Defect. Amcr. J. Cardiol., 15: 386,
1965.
Woodward. T. E., Baker. E. L., and Serpick.
A. A. : Motor System Disease. Review and
Discussion of a Case Presenting with Alveo-
lar Hypoventilation, Arch. Intern. Med., 115:
192, 1965.
Division of Dermatology
Berestox. E. S. : Contact Dermatitis in the
Home and in Industry. W. Virginia Med. J.,
66-73, 1964.
Berestox, E. S., and Roberts, Daxiel : Con-
genital Hypertrophy of Limbs, Southern Med.
J.. 58: 302, 1965.
Burnett, J. W., and Pathak, M. A.: The
Porphyrin Content of Skin, /. Invest. Derm.,
43: 119-120, 1964.
Burnett, J. W., and Pathak, M. A. : The
Intracellular Localization of Porphyria. /.
Invest. Derm., 43: 421-27, 1964.
Burnett, J. W., and Frothingham, T. E. :
The Cytopathic Effect of Fowlpox Suspensions
in Primary Human Amnion Cell Cultures in
Clinical Research. In press.
Frothixgham, T. E., and Burxett, J. W. :
The Cytopathic Effect of Fowlpox Suspensions
in Primary Human .\mnion Cell Cultures in
Clinical Research. In press.
Harmon, L. E. : Melanogenesis and Pigmentary
Disturbances, Natl. Med. J., 56: 501, 1964.
Pathak. M. A., and Burnett. J. W. : The
Porphyrin Content of Skin, /. Invest. Derm.,
43: 119-120, 1964.
Pathak, M. A., and Burnett. J. W. : The
Intracellular Localization of Porphyria, /.
Invest. Derm.. 43: 421-27, 1964.
Raskin. Joan, and Robixsox, H. M., Jr.':
Tolnaftatc, a Potent Topical Antifungal
Agent, Arch. Derm. (Chicago), 91: 372, 1965.
Raskin, Joan : Fluorescent Antibody Studies
of Certain Dermatoses, Arch. Derm. (Qii-
cago), 569, 579, 1964.
Raskin, Jo.\n : Cutaneous Lesions Associated
with Cardiac Dysfunction, Maryland Med. I.,
1312: 59-61, 1964.
Roberts, Daniel, and Bereston, E. S. : Con-
genital Hypertrophy of Limbs, Southern Med.
/., 58: 302, 1965.
Robinson, H. M., Jr.. and Raskin, Joan:
Tolnaftate, a Potent Topical Antifungal
Agent, Arch. Derm. (Chicago), 91: 372,
1965.
Robinson, H. M., Jr.: Rehabilitation, Arch.
Derm. (Chicago), 91: 128-205, 1965.
Robinson, H. M., Jr. : Das Lipoid-Histocytom-
Der Hautarzi, 15, Jahrgang, 6 Heft, 323-24,
1964.
Robinson, R. C. V. : Long Term Therapy with
Sulfadimethoxine, Toxicity Studies, Southern
Med. J. In press.
Robinson, R. C. V. : Allergic and Inflammatory
Dermatoses, Curr. Med. Dig. In press.
Robinson, R. C. V. : Fungas Diseases in Gen-
eral Practice, Curr. Med. Dig. In press.
Robinson, R. C. V. : The Aging Skin, Bull.
Maryland Acad. Gen. Practice. In press.
Division of Endocrinology and Metabolism
Bacmgardner, George R., Stauffer, Martha
E., Wright, James C, Connor, Thomas B.,
and Blizzard, Robert M. : L'rinary Hydroxy-
proline as a Pleasure of Growth Hormone
Activity in Man. Forty-fifth Meeting of the
Endrocrine Society held in Atlantic City,
New Jersey, June 13-15, 1963.
Baumgardner, G., Stauffer, M., and Connor,
T. B. : Bone Matrix Metabolism in Parathy-
roid Disease. Clin. Res.. 11: 2-214. 1963.
July, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Baumgardner, G., Stauffer, M.. Heck, A. F.,
and Connor. T. B. : Reversible Muscular
Atrophy in Hyperparathyroidism, Neurology,
14: 256-257, 1964 (abstract).
Bessman, Samuel, P. : Amino Acid Excretion
Following Administration of C14 Labeled
Histidine in Children with Cerebro Macular
Degeneration. Presented at the First Pan
American Congress of Neurology in Lima,
Peru, October 20-25, 1963.
Bessman. Samuel P. : Phenyliketonuria, Med.
Sci.. 16: 35, 1965.
Blizzard, Robert M., Connor, Thomas, B.,
Wright, James C, Stauffer, Martha E.,
and Baumgardner, George R. : Urinary
Hydroxyproline as a Measure of Growth
Hormone Activity in Man. Forty-fifth Meet-
ing of the Endocrine Society held in Atlantic
City, New Jersey. June 13-15, 1963.
Connor, Thomas B., Wright, James C,
Stauffer, Martha E., Baumgardner,
George R., and Blizzard, Robert M. : Uri-
nary Hydroxyproline as a Measure of Growth
Hormone Activity in Man. Forty-fifth Meet-
ing of the Endocrine Society held in Atlantic
City, New Jersey, June 13-15, 1963.
Connor, T. B., Stauffer, M., and Baumgard-
ner, G. : Bone Matrix Metabolism in Para-
thyroid Disease, Clin. Res., 11: 2-214, 1963.
Connor. T. B., and Lovice^ Harris: Observa-
tions on Renal Function Before and After
Correction of Hypercalcemia, Tran.<:. Amer.
Clin. Cliinat. Ass.. 74: 1962, published August,
1963.
Connor, T. B., and Workman. Joseph B. :
Preoperative Localization of Parathyroid
Adenomata, /. Niiel. Med.. 5: 372-373, 1964
■ ( abstract ) .
Connor. T. B., Heck, A. F., Stauffer. J. C,
and Baumgardner. G. R. : Reversible Muscu-
lar Atrophy in Hyperparathyroidism, Neur-
ology. 14: 256-257. 1964 (abstract).
Connor. T. B., Ganis, F. M., Levin, H. S.,
Martin, L. G., and Waldasin, G. L. :
Clinical and Biochemical Studies in a Gonado-
tropin Dependent Virilizing Ovarian Tumor,
Clin. Res.. 13: 243, 1965 (abstract).
Connor. T. B., Wildasin. G. L., and Ganis,
F. M. : In Vitro Production of Dehydroepian-
drosterone by Virilizing Krukenberg Tumor
of the Ovary, Fed. Proc., 24: 535, (Part I),
1965.
Connor. T. B., Scott, S. H., Huffer, V., and
Lovice. H. : Psychological Studies of Adult
Male Patients with Sexual Infantilism Be-
fore and After Andogen Therapy, .Inn. In-
tern. Med.. 61: 2, 1964.
Ganis. Frank, M. : A Convenient Beaker
Holder, Chemist-Analyst, 53: 52, 1964.
Ganis. F. M., Connor. T. B., Levin, H. S.,
Martin, L. G., and Wildasin, G. L. :
Clinical and Biochemical Studies in a Gona-
dotropin Dependent Virilizing Ovarian
Tumor, Clin. Res.. 13: 243, 1965 (abstract).
Ganis. F. M., Wildasin, G. L., and Connor,
T. B. : In Vitro Production of Dehydroepian-
drosterone by Virilizing Krukenberg Tumor
of the Ovary, Fed. Proc.. 24: 535, (Part I),
1965.
Good. Thomas A. : Studies on the Types of
Gargoylism and Acid Mucopolysaccharide
Excretion. Presented at the Third Pan
American Congress on Rheumatic Diseases at
Santiago, Chile, October 15-19, 1963.
Heck, A. F., Connor, T. B., Stauffer, J. C,
and Baumgardner. G. R. : Reversible Muscu-
lar Atrophy in Hyperparathyroidism, Neur-
ology, 14: 256-257, 1964 (abstract).
Huffer, V., Scott, W. H., Connor, T. B., and
Lovice, H. : Psychological Studies of Adult
Male Patients with Sexual Infantilism Before
and After Androgen Therapy, Ann. Intern.
Med.. 61: 2, 1964.
Levin. H. S., Connor, T. B., Ganis. F. M.,
Martin, L. G., and Wildasin, G. L. ;
Clinical and Biochemical Studies in Gona-
dotropin Dependent Virilizing Ovarian
Tumor, Clin. Res., 13: 243, 1965 (abstract).
Lovice. Harris, and Connor, T. B. : Observa-
tions on Renal Function Before and After
Correction of Hypercalcemia, Trans. Amer.
Clin. Cliniat. Ass.. 74: 1962, published .August,
1963.
Lovice. H., Connor, T. B.. Scott, S. H., and
Huffer. V.: Psychological Studies of Adult
Male Patients with Sexual Infantilism Be-
fore and after Androgen Therapy, Ann. Inter.
Med.. 61: 2, 1964.
Martin, L. G., Levin, H. S., Connor, T. B.,
Ganis, F. M., and Wildasin, G. L. : Clinical
and Biochemical Studies in a Gonadotropin
Dependent Virilizing Ovarian Tumor, Clin.
Res., 13: 243, 1965 (abstract).
RouBEx, M. J.. S.\CKS. M. S., and Spurling,
C. L. : Juvenile Pernicious Anemia, Nczi'
Eng. J. Med.. 271: 995-1003, 1964.
r<)/. M, No. 3
MEDICAL SCHOOL SECTIOX
Sacks. M. S., Spurlinx. C. L., and Rolbex.
M. T. : Juvenile Pernicious Anemia, Xczc
Eiui. J. Med.. 271: 9<)5-1003, l')64.
Scott. W. H., Hlkkek. X ., Connor. T. B.. and
LoviCE. H. : Psychological Studies of Adult
i[ale Patients with Sexual Infantilism Be-
fore and After Androgen Therapy, Ann.
Intern. Med.. 61: 2. 1964.
Si'VRLixG. C. L., Sacks. M. S., and Roitben,
M. J.: Juvenile Pernicious Anemia, A'ltc Eng.
J. Med.. 271: 995-1003, 1964.
Stavffer. Martha E.. Baumgardner, George
R., Wright. James C. Connor. THo^^AS B.,
and Blizzard. Robert M. : Urinary Hydro.xy-
proline as a Measure of Growth Hormone
-Activity in Man. Forty-fifth Meeting of the
Endocrine Society held in Atlantic City, Xew
Jersey, June 13-15, 1963.
Stauffer. M., Baumgardner, G., and Connor.
T. B. : Bone Matrix Metabolism in Parathy-
roid Disease, Clin. Res., 11: 2-214, 1963.
Stalffer. M., Connor. T. B., Heck, A. P., and
Baumgardner. G. R. : Reversible Muscular
.Atrophy in Hyperparathyroidism, X'eiirology,
14: 256-257, 1964 (abstract).
Wildasin, G. L., Martin, L. G., Levin. H. S.,
CoN.NOR, T. B.. and G.\Nis, F. M. : Clinical
and Biochemical Studies in a Gonadotropin
Dependent \'irilizing Ovarian Tumor, Clin.
Res.. 13: 243. 1965 (abstract).
^\'ILDASIN, G. L., G.\Nis. F. M., and Connor,
T. B. : In Vitro Production of Dehj-droepian-
drosterone by Virilizing Krukenberg Tumor
of the Ovary. Fed. Proe., 24: 425, (Part I),
1965.
^^'oRKMAN, J. B., and Connor, T. B. : Pre-
operative Localization of Parathyroid Adeno-
mata, /. Nuc. Med., 5: 372-i7i, 1964 (ab-
stract).
A\"right, James C, Stauffer, Marth.\ E.,
B.\umcardner, George R., Connor, Thom-\s
B., and Blizzard, Robert M. : Urinary Hy-
dro-xyproline as a Measure of Growth Hor-
mone .Activity in Man. Forty-fifth Meeting
of the Endocrine Society held in Atlantic
Cit}-, X'ew Jersey, June 13-15, 1963.
Division of Hypertensive — Renal Diseases
Asplen, C. H., Borges, F. J., and Wood, C. :
-Acute Renal Failure -After Oral Cholecysto-
graphy, /. Lancet, 2: 340, 1964.
AsPLE.N, C. H., Borges, F. J., and A\'ood, C. :
Renal Failure -After Cholecystography, /.
Urol.. 4: 54, 1965.
-Attar, S., Borges. F., Esmond, W. G., Blair,
E.. and Cowley. R. A. : Prevention of Renal
Failure in Open Heart Surgery. Proceedings
of .Xational Congress of Surgery. liucharesl,
Rumania.
Blair, E., Esmond, W. G., Borges, F. J., .Xttar,
S., and Cowlev, R. A.: Prevention of Renal
Failure in Open Heart Surgery. Proceedings
of Xational Congress of Surgery, Bucharest,
Rumania.
Borges. F. J., .-\sple.n-. C. H., and Wood. C. :
-Acute Renal Failure .Alter Oral Cholecysto-
graphy. Lancet, 2: 340, 1964.
Borges. F. J., Wood, C, and Asplen, C. H. :
Renal Failure After Cholecystography, /.
Urol., 4: 54, 1965.
Borges. F. J., .Attar. S., Esmond. W. G.,
Blair, E., and Cowlev. R. .A. : Prevention
of Renal Failure in Open Heart Surgery.
Proceedings of Xational Congress of Surgery,
Bucharest, Rumania.
Cowlev, R. A., Blair, E., Es.mond. W. G.,
Borges. F. J., and .Attar, S. : Prevention
of Renal Failure in Open Heart Surgery.
Proceedings of National Congress of Surgery,
Bucharest, Rumania.
Esmond, W. G., Borges, F. J., .Attar, S.,
Blair, E., and Cowley, R. .A. : Prevention
of Renal Failure in Open Heart Surgery.
Proceedings of Xational Congress of Surgery,
Bucharest, Rumania.
Wood, C, Asplen, C. H., and Borges, F. J. :
-Acute Renal Failure After Oral Cholecysto-
graphy, Lancet, 2: 340, 1964.
Wood, C, Borges, F. J., and Asplen, C. H. :
Renal Failure After Cholecystography. /.
Urol., 4: 54, 1965.
Division of Infectious Diseases
Eigelsbach, H. T., and Hornick. R. B.:
Occupational Tularemia. Occupational Dis-
eases Acquired from Animals. Published by
the University of Michigan School of Public
Health, pp. 295-301, 1964 (monograph).
EwALD, R. W., Hornick. R. B., Schubart,
-A. F., Schroeder, W. C, Myerburg. R. J.,
Goodman. J. S., and Woodward, T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever, /.
Immun., 93: 387-395, 1964
Good.man, J. S., Myerburg, R. J., Schroeder,
W. C, EwALD, R. W., Hornick, R. B.,
Schubart, -A. F., and Woodward, T. E. :
/i(/v. ^66
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Changes of Serum Complement and Proper-
din Levels in Experimental Typhoid Fever,
J. ImmuH., 93: 387-395, 1964.
Herring, R. D., Hornick, R. B., and Eigels-
BACH, H. T. : Tularemia Prophylaxis : New
Liver Vaccine Strains. American Society for
Microbiology, April, 196S (abstract).
Hornick, R. B., and Eigelsbach, T. T. : Occu-
pational Tularemia. Occupational Diseases Ac-
quired from Animals. Published by the Uni-
versity of Michigan School of Public Health,
pp. 295-301, 1964 (monograph).
Hornick, R. B., and Overholt, E. : Primary
Cutaneous Coccidioidomycosis, Arch. Int.
Med.. 114: 149-153, 1964.
Hornick, R. B., Schubart, A. F., Ewald,
R. W., Schroeder, W. C, Myerburg, R. J.,
Goodman, J. S., and Woodward. T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever, /.
Immun., 93: 387-395, 1964.
Hornick, R. B. : Typhoid Fever, Ticc's Text-
book of Medicine. In press.
Hornick, R. B., and Woodward, T. E. : Typhoid
Fever and Rickettsial Diseases, Harrison's
Textbook of Medicine. In preparation.
Jackson, E., and Smadel, J. : Rickettsial In-
fections, Diagnostic Procedures III Edition,
November, 1964.
Myerburg, R. J., Schroeder, W. C, Ewald,
R. W., Hornick, R. B., Schubart, A. F.,
Goodman, J. S., and Woodward. T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever, /.
Immun. 93: 387-395, 1964.
OvERHOLT, E., and Hornick, R. B. : Primary
Cutaneous Coccidioidomycosis, Arch. Int.
Med., 114: 149-153, 1964.
Schroeder, W. C, Ewald, R. W., Hornick,
R. B., Schubart, A. F., Myerburg, R. J.,
Goodman, J. S., and Woodward, T. E. :
Changes of Serum Complement and Properdin
Levels in Experimental Typhoid Fever,
/. Immun., 93: 387-395, 1964.
Schubart, A. F., Hornick, R. B., Ewald,
R. W., Schroeder, W. C, Myerburg, R. J.,
Goodman, J. S., and Woodward. T. E. :
Changes of Serum Complement and Proper-
din Levels in Experimental Typhoid Fever,
J. Immun., 93: 387-395, 1964.
Smadel, J., and Jackson, E. : Rickettsial In-
fections, Diagnostic Procedures III Edition,
November, 1964.
Togo, Y. : Hemagglutination-Inhibition Test in
the Study of Measles Immunity. Amcr. J.
Hyg.. 79: 250-259, 1964.
Woodward, T. E., Goodman. J. S., Myerburg,
R. J., Schroeder, W. C, Ewald, R. W.,
Hornick, R. B., and Schubart, A. F. :
Changes of Serum Complement and Proper-
din Levels in Experimental Typhoid Fever,
/. Immun., 93: 387-395, 1964.
Woodward, T. E., and Hornick, R. B.:
Typhoid Fever and Rickettsial Diseases,
Harrison's Tc.rtbook of .Medicine. In prepara-
tion.
Division of Pulmonary Diseases
Blide, R. W., Kerr, H. D.. and Spicer, W. S.,
Jr. : Measurement of Upper and Lower Air-
way' Resistance and Conductance in Man, /.
Appl. Physiol., 19: 6, 1964
Blide. R. W. : Obstructive Emphysema and
Pulmonary Heart Disease, Maryland Med. J.,
September, 1964.
Christiansox, C, Simpson, D. G., McClem-
ENT, J., and Hubaytar. R. : In the Treatment
of Chronic Obstructive Pulmonary Disease,
Ann. N. Y. Acad. Sci., March, 1965.
Hubaytar, R., Christianson, C, Simpson,
D. G., and McClement. J. : In the Treatment
of Chronic Obstructive Pulmonary Disease,
Ann. A'. Y. Acad. Sci., March, 1965.
Kerr, H. D., Blide, R. W., and Spicer, W. S.,
Jr. : Measurement of Copper and Lower Air-
way Resistance and Conductance in Man, /.
Appl. Physiol.. 19: 6, 1964.
Kerr, H. D., and Spicer. W. S., Jr. : Variation
of Respiratory Function in Patients and
Normal Subjects. Submitted for publication.
Kowitz, T. a.: Editorial: Percutaneous Biopsy
of tlie Parietal Pleura, Maryland Med. J.,
13: 63, 1964.
McCle.ment, J., and Simpson, D. G. : Adrenal
Corticosteroids in Pulmonary Tuberculosis,
.4mer. Rev. Resp. Dis., November, 1964.
McClement, J., Simpson, D. G., Christ-
iansox, C, and Hubaytar, R. : In the Treat-
ment of Chronic Obstructive Pulmonary Dis-
ease, .-Inn. N. )'. Acad. Sci., March, 1965.
Morgan, W. K. C. : Bacillus Calmette Guerin,
.Maryland Med. J., July, 1964.
Morgan. W. K. C. : .\ Controlled Trial of
Steroids in Obstructive Airway Disease, Ann.
Intern. Med., .\ugust, 1964.
Uol. .^7, .V,i. 3
MEDICAL SCHOOL SECTIOX
MuKi'.AX, W. K. C. : Rheumatoid Pneumoconi-
osis in Association witli Asbestosis, Thorax,
September, 1964.
Morgan, W. K. C. : Cbronic Obstructive Air-
way Disease : Bacterial and Cellular Content
of Sputum, Anii-riiaii Kri: A'l'j/'. Dis.. No-
vember, 1 964.
^^ORG.\^•. W. K. C. : The Englisli Disease,
M<irYliiiui Mrd. J.. Marcli. 1"65.
MoRG.\x. \V. K. C. : The Antibody Response
to H. influenzae in Obstructive Airway
Disease, Lancet. In press.
Simpson, D. G., and McClemext. J. : Adrenal
Corticosteroids in Pulmonary Tuberculosis,
Aiiier. Rev. Rcsp. Dis., November, 1964.
Simpson, D. G., McClement, J., and Christ-
lAXsox, C, and Hub.wtar, R. : In the treat-
ment of Chronic Obstructive Pulmonary
Disease, Ann. X. V. Acad. Sci.. March, 1965.
Spicer. W". S., Jr., Kerr, H. D., and Blide,
R. W. : Measurement of Upper and Lower
Airway Resistance and Conductance in Man,
/. A/'pl. Physiol., 19: 6, 1964.
Spicer. W. S., Jr. : Relation of Air Pollution to
Disease, Arch. Em: Health, 9: 600, 1964.
Spicer. \V. S., Jr.. and Kerr, H. D. : Variation
of Respiratory Function in Patients and
Xormal Subjects. Submitted for publication.
DEPARTMENT OF MICROBIOLOGY
.\uDv. J. R.. X.\DCH.\TR.-\.M, M., LooMis, R., and
Tr.wb. R. : Troinbicnla minor Berlese
( .\carina. Trombiculidae). Designation of
Xeotype with Larval and Post-larval Stages
from Malayan Bats, and New Name, Myo-
trombicida dilarami, for T. minor, Cooreman
1960 ncc Berlese, 1905, Acarologia. . .: 1-34,
illus., rets., 1965. In press.
El Bat.\wi, Y., Hatgi, J. N., Eylar, O. R.,
HoLLJES, H. W. D., Rosexzweig, E. C,
Wisseman, C. L., Jr., Noriega, A. R., and
Wood, \\'. H., Jr. : Attenuated Living Vac-
cines for Dengue Fever. II. Clinical and Im-
munological Responses of Man to Infection
with Four Attenuated Type I Dengue Virus
Strains, 1965. In press.
Evlar, O. R., Holljes. H. W. D., Rosexzweig,
E. C, Wisse.man, C. L., Jr., Hatgi, J. N.,
El B.\tawi, Y.. Noriega, A. R., and Wood,
'W. H., Jr. : Attenuated Living Vaccines for
Dengue Fever. II. Clinical and Immunological
Response of Man to Infection with Four
Attenuated Type I Dengue Virus Strains,
1965. In press.
FiSET. Pall : Chapter on Serological Tech-
ni(|ues. Techniques in Experimental Virology
edited by R. J. C. Harris, Academic Press,
London, November, 1964.
Harrington, B. R., Rosenzweig, E. C, Wisse-
man, C. L., Jr., Hatgi, J. N., and Kitaoka,
M. : Immunological Studies with Group B
.•\rthropod-borne Viruses. VI. Hemaggluti-
nation-Inhibiting Antibody Responses to 17D
Yellow Fever Vaccine in Human Subjects
with Different Degrees of Complexity of Pre-
vaccination Group B Virus Experience, 1965.
In press.
Hatgi. J. N., Wisseman, C. L., Jr., Rosen-
zweig. E. C, Harrixgtox, B. R., and Kit.\-
oka, M. : Immunological Studies with Group
B .'\rthropod-borne Viruses. VI. Hemagglu-
tination-Inhibiting Antibody Responses to 17D
Yellow Fever Vaccine in Human Subjects
with Different Degrees of Complexity of
Prevaccination Group B Virus Experience,
1965. In press.
Hatgi, J. N., Eylar, O. R., Holljes, H. W. D.,
Rosenzweig, E. C, Wisseman, C. L., Jr.,
El Batawi, Y., Noriega A. R., and Wood,
W. H., Jr. : Attenuated Living Vaccines for
Dengue Fever. II. Clinical and Immunological
Response of Man to Infection with Four At-
tenuated Type I Dengue Virus Strains, 1965.
In press.
Holljes, H. W. D., Rosenzweig, E. C, Wisse-
man, C. L., Jr., Evlar, O. R., Hatgi, J. N.,
El Batawi, Y., Noriega, A. R., and Wood,
W. H., Jr. : Attenuated Living Vaccines for
Dengue Fever. II. Clinical and Immunological
Responses of Alan to Infection with Four
Attenuated Type I Degree Virus Strains,
1965. In press.
Kitaoka, M., Harrington, B. R., Rosen-
zweig, E. C, Wisseman, C. L., Jr., and
Hatgi, J. N. : Immunological Studies with
Group B Arthropod-borne Viruses. VI. Hem-
agglutination-Inhibiting Antibody Responses
to 17D Yellow Fever Vaccine in Human Sub-
jects with Different Degrees of Complexity
of Prevaccination Group B Virus Experience,
1965. In press.
Lakshana, p., and Traub, R. : Some Chiggers
of the Subgenus Leptotrombidium from Thai-
land, w-ith Descriptions of New Species
(Acarina, Trombiculidae). /. Med. Ent.,
1965. In press.
LooMis, R., Nadchatram, M., Audy, J. R., and
Tr.aub, R. : Trombiciila minor Berlese (Acar-
Jnly. 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UXIVERSITV OF MARYLAND
ina, Trombiculidae). Designation of Neotype
with Larval and Post-larval Stages from
Malayan Bats, and New Name, Myotrombi-
cula dUarami, for T. minor, Cooreman 1960
ncc Berlese, 1905. Acarologia : 1-34.
illus., refs., 1965. In press.
Nadchatram, M., and Traub, R. : New Species
of Chiggers from Rodents in Laos (Acarina,
Trombiculidae), /. Med. Ent.. 1: 65-72, illus.,
refs., 1964.
Nadchatram, M., and Traub, R. : Three New
Species of Leptobrobidiiim ( Lorillatum) from
Southeast Asia (".^carina, Trombiculidae),
/. Med. Ent., 1: 268-276, illus., refs., 1964.
Nadchatram, M., and Traub. R. : A Revision
of the Genus Chatia Brennan, with Synony-
mic Notes and Descriptions of Two New
Species from Pakistan (Acarina, Trombiculi-
dae), 1965. In press.
Nadchatram, M., Audy, J. R., Loomis. R. and
Traub, R. : Tromhicula minor Berlese (Acar-
ina, Trombiculidae). Designation of Xeotype
with Larval and Post-larval Stages from
Malayan Bats, and New Name, Myotrombi-
ciila dUarami, for T. minor, Cooreman 1960
ncc Berlese, 1905. Acarologia . . . . : 1-34.
illus., refs., 1965. In press.
Noriega, A. R., El Batawi. Y., Hatgi. J. X.,
Evlar, O. R.. Holltes. H. W. D., Rosex-
ZWEIG. E. C, WissEMAX, C. L., Jr.. and
Wood, W. H., Jr. : Attenuated Living \'ac-
cines for Dengue Fever. II. Clinical Im-
munological Responses of Man to Infection
with Four Attenuated Type I Dengue \'irus
Strains, 1965. In press.
ROSENZWEIG, E. C, WiSSEMAN. C. L., Jr.,
Hatgi, J. N., Harrington, B. R., and Kita-
OKA, M. : Immunological Studies with Group
B. Arthropod-borne Viruses. VI. Hemaggluti-
nation-Inhibiting .\ntibody Responses to 17D
Yellow Fever ^'accine in Human Subjects
with Different Degrees of Complexity of Pre-
vaccination Group B \'irus Experience, 1965.
In press.
ROSENZWEIG. E. C, WiSSEMAX. C. L., Jr.,
HOLLJES, H. \V. D., EVLAK, O. R.. H.^TGI,
J. N., El Batawi, Y., Noriega, A. R., and
Wood, W. H., Jr. : Attenuated Living Vac-
cines for Dengue Fever. II. Clinical and Im-
munological Responses of Man to Infection
with Four .Attenuated Type I Dengue Virus
Strains, 1965. In press.
Schultz, R. B., and Smith, A. G. : Observa-
tions on the Disposition of Aspergillus Fumi-
gatus in the Respiratory Tract, Aincr. J. Clin.
Pa til.. 1965. In press.
Smith. A. G., and Schultz, R. B. : Obser-
vations on the Disposition of Aspergillus
Fumigatus in the Respiratory Tract, Amcr.
J. Clin. Path., 1965. In press.
Tabor. H.. and Wisseman. C. L., Jr. : Inter-
action of Rickettsiae and Phagocytic Host
Cells. IV. Early Callular Response of Man
to Typhus Rickettsiae as Revealed by the
Skin Window Technique, with Observations
on in I'i'c'o Phagocytosis, /. Iinniun.. 93:
816-825, 1964.
Traub, R. : .\ New Subgenus of Ophthal-
niol^sylla from Gilgit, West Pakistan, and a
New Hot>kinsil^sylla from Libya ( Siphonap-
tera, Leptopsyllidae), /. Med. Ent.. 1965. In
press.
Tr.\ub. R. : Flea, article in Encycl. Brit., 9:
431-432, 1964, Wm. Benton, Publisher,
Chicago.
Traub, R., and Nadchatram, M. : New Species
of Chiggers from Rodents in Laos (Acarina,
Trombiculidae), /. Med. Ent.. 1: 65-72, illus.,
refs., 1964.
Traub, R., and Nadchatram. M. : Three New
Species of Lcptotrombidium (Lorillatum)
from Southeast Asia (Acarina, Trombiculi-
dae). ./. Med. Ent.. 1: 268-276. illus.. refs.,
1964.
Traub, R. : Some Opportunities and Problems
in Medical Entomology in the Asian-Pacific
Region. Dedication Symposiimi of Pauahi
Hall, Bishop Museum, Pacific Insects, 7: 21-
28, 1965.
Traub. R., and Lakshaxa. P. : Some Chiggers
of the Subgenus Leptotrombidiunt from Thai-
land, with Descriptions of New Species
(Acarina, Trombiculidae), /. Med. Ent., 1965.
In press.
Traub, R., and Xadch.\tram, M. : A Revision
of the Genus Chatia Brennan, with Synonymic
N^otes and Descriptions of Two Species from
Pakistan (.\carina. Trombiculidae), 1965.
In press.
Traub. R., Loomis, R., Nadchatram. M. and
Audv. J. R. : Tromhicula minor Berlese
(Acarina. Trombiculidae). Designation of
Neotype with Larval and Post-larval Stages
from Malayan Bats, and New Name, Myo-
tronddeula dilarami. for T. minor, Cooreman
1960 nee Berlese, 1905. Acarologia . . .: 1-34,
illus., refs.. 1965. In press.
I'ol. .^;. .V-). 3
MEDICAL SCHOOL SECTIOX
WissEMAX. C. L., Jk.. and Tabor, H. : Inter-
action of Rickettsiae and Phagocytic Host
Cells. IV. Early Cellular Response of Man
to Typhus Rickettsiae as Revealed by the
Skin Window Technique, with Oliservations
on 1)1 I'iro Phagocytosis. /. liiitinm., 93:
816-825. 1964.
WisSE.MAX, C. L., Jr.: Typhus Fevers, Coitn.
Current Therapy, pp. 64-66, 1%5. W. B.
Saunders. Philadelphia.
W'issF.MAX, C. L., Jr.: Ininiunization Against
Epidemic Typhus with .Strain E : Recent
Studies in the U. S. -\. Proc. 7th Inter-
national Congresses on Tropical Medicine and
Malaria, Vol. 3, pp. 284-285, 1964.
W'issEMAx. C. L., Jr., Hatgi. J. X., Rosex-
ZWEIG. E. C, Harrixgtox. B. R., and Kita-
OKA. M. : Immunological Studies with Group
B .Arthropod-borne Viruses. VI. Hemagglu-
tination-Inhibiting .Antibody Responses to 17D
Yellow Fever \'accine in Human Subjects
with Different Degrees of Complexity of
Prevaccination Group B \'irus Experience,
1965. In press.
WissEMAX. C. L., Jr., Rosexzweig, E. C,
HoLLjES. H. W. D., Evlar, O. R., Hatgi,
J. N., El Batawi, Y., Xoriega. A. R., and
Wood, \\'. H., Jr. : Attenuated Living Vac-
cines for Dengue Fever. II. Clinical and Im-
munological Responses of Man to Infection
with Four Attenuated Type I Dengue Virus
Strains, 1965. In press.
Wood, W. H., Jr., Noriega, A. R., El Batawi,
Y., Hatgi, J. N., Eylar, G. R., Holljes,
H. W. D., Rosenzweig, E. C, Wisseman,
C. L., Jr. : Attenuated Living Vaccines for
Dengue Fever. II. Clinical Immunological
Responses of Man to Infection with Four
Attenuated Type I Dengue \'irus Strains,
1965. In press.
DEPARTMENT OF NEUROLOGY
IAuREBECK, G., OsterberGj K., Blaw, M., Chou,
S., and Nelson, E. : Electron Microscopic
Studies on Metachromatic Leukocystrophy,
Arch. Neurol, 11: 273, 1964.
Baumgardxer, G., St.'Vuffer, J., Connor, T.,
and Heck. A. : Reversible Muscular Atrophy
- in Hyperparathyroidism. (Paper given at
I 16th Annual Meeting. American .Academy of
» NeurologA', Denver, Colorado, April 28, 1964.)
Neurology, 14: 256-257, 1964 (abstract).
Blaw, M., Osterberg, K., .Aurebeck, G., Chou,
S., and Xelsox. E. : Election ^licroscopic
Studies on Metacliromatic Leukocystrophy.
Arch. Neurol, 11: 273, 1964.
Blaw, M., Osterberg, K., Kozak, P., and
Nelson, E. : Sudanophilic Leukodystrophy
and .Adrenal Cortical .Atrophy, Arch. Neurol.,
11: 626, 1964.
Cacciano, v., Hall, V., and Heck, A.: An
On-Line System for Recording Physiological
Time Intervals, Aiiicr. J. Med. Electronics.
In press.
Chou, S., Blaw, M., Osterberg, K., Aure-
beck, G., and Nelson, E, : Electron Micro-
scopic Studies on Metachromatic Leukocystro-
phy, Arch. Neurol., 11: 273, 1964.
Cox.xoR, T., Heck, A., Stauffer, J., and Baum-
G.-\RDXER, G. : Reversible Muscular Atrophy
in Hyperparathyroidism. (Paper given at
16th Annual Meeting, American Academy of
X^eurology, Denver, Colorado, April 28, 1964.)
Neurology, 14: 256-57, 1964 (abstract).
Dahl, E., and Nelson, E. : Electron Micro-
scopy of Human Intracranial Arteries, Arch.
Neurol, 10: 158, 1964.
Dahl, E., Flora, G., and X^elsox, E. : Ultra-
structural Observations on X''ormaI Human
Intracranial Arteries, Neurology, 15: 132,
1965.
Duffell, D., Hixz, R., and X^elsox, E. : Ultra-
structural Observations on SV-40 Induced
Gliomas in Hamsters, Amer. J. Path., 45: 59,
1964.
Flora, G., Dahl, E., and Xelsox, E. : Ultra-
structural Observations on X''ormal Human
Intracranial Arteries, Neurology. 15: 132,
1965.
Goulding, Monroe, Kramer, and Wise: EEG
Activation of Patients Receiving Pheno-
thiazines and/or Chloradizepoxide. Accepted
for publication in /. Nerv. Ment. Dis.
Greenbaum, Jr., L. J., and Merlis, J. K. : Ex-
citability Cycles of Different Gyri of Cat
Cortex, Electroenceph. Clin. Neurophysiol.,
18: 109-117, 1965.
Hall, V., and Heck, A. : A Technique for
Differential Photoelectric Plethysmography
of Brain and Ear, /. Appl. Physiol, 19: 1236-
1239, 1964.
Hall, V., Caggiaxo, V., and Heck, A. : An
On-Line System for Recording Physiological
Time Intervals, Amer. J. Med. Electronics.
In press.
Heck, A., and Hall, V. : A Technique for
Differential Photoelectric Plethysmography
Julw 1966
BULLETIN OF THE SCHOOL OF MEDICINE. L'.MrERSITV OF MARYLAND
of Brain and Ear, /. Appl. PhysioL, 19: 1236-
1239, 1964.
Heck, A. : A Study of Neural and Extraneural
Findings in a Large Family with Friedreich's
Ataxia, /. Neurol. Sci, 1: 226-255, 1964.
Heck, A., Hall, V., and Caggiano, V. : An
On-Line System for Recording Physiological
Time Intervals, Amcr. J. Med. Electronics.
In press.
Heck, A., Connor, T., Stauffer, J., Baum-
GARDNER, G. : Reversible Muscular Atrophy
in Hyperparathyroidism. (Paper given at
16th Annual Meeting, American Academy of
Neurology, Denver, Colorado, April 28, 1964.)
Neurology, 14: 256-257, 1964 (abstract).
HiNZ, R., DuFFELL, D., and Nelson, E. : Ultra-
structural Observations on SV-40 Induced
Gliomas in Hampsters, Amcr. .L. Path., 45:
59, 1964.
KOZAK, P., OSTERBERG, K., Blaw, AL, and
Nelson, E. : Sudanophilic Leukodystrophy
and Adrenal Cortical Atrophy, Arch. Neurol,
11: 626, 1964.
Kramer, Monroe, Goulding and Wise: EEG
Activation of Patients Receiving Phenothia-
zines and/or Chloradiazepoxide. Accepted for
publication in J. Ncrv. Ment. Dis.
Merlis, J. K., and Greenbaum, Jr., L. J. : Ex-
citability Cycles of Different Gyri of Cat
Cortex, Elcctroenceph. Clin, Neuroj^hysiol..
18: 109-117, 1965.
Merlis, J. K. : Excitability Cycle of the Direct
Cortical Response Studies with Minimal
Stimuli and Response Averaging, Electroen-
ceph. Clin. Neurophysiol, 18: 118-123, 1965.
Merlis, J. K. : Book Review: Electroencephal-
ography in Hospital and General Consulting
Practice ; An Introduction, J. Kugler,
J.A.M.A., 189: 194, 1964.
Merlis, J. K. : Book Review : Neurological and
Electroencephalographic Correlative Studies
in Infancy, P. Kellaway and I. Petersen.
J. A.M. A., 191: 349, 1965.
Merlis, J. K. : Book Review: Actualites Neu-
rophysiologiques. Quatrieme serie, A. M.
Monnier, P. Laget et A. Monnier, Electro-
enceph. Clin. Neurophysiol, 18: 321, 1965.
Monroe, Kramer, Goulding, and Wise: EEG
Activation of Patients Receiving Phenothia-
zines and/or Chloradizepoxide. Accepted for
publication in /. Nerv. Ment. Dis.
Nelson, E., and Dahl, E. : Electron Micro-
scopy of Human Intracranial Arteries, Arch.
Neurol., 10: 158, 1964.
Nelson, E., Hinz, R., and Duffell, D. : Ultra-
structural Observations on SV-40 Induced
Gliomas in Hamsters, Aiiier. J. Path, 45: 59,
1964.
Nelsox, E., Chou, S., Blaw, M., Osterberg,
K., and Aurebeck, G. : Electron Microscopic
Studies on Metachromatic Leukocystrophy,
Arch. Neurol, 11: 273, 1964.
Nelson, E., Kozak, P., Osterberg, K., and
Blaw, M. : Sudanophilic Leukodystrophy and
Adrenal Cortical Atrophy, Arch. Neurol.,
11: 626, 1964.
Nelson, E., Flora, G., and Dahl, E. : Ultra-
structural Observations on Normal Human In-
tracranial Arteries, Neurology, 15: 132, 1965.
Oldstone, M. B. a. : Stethoscope Treachery,
Nciv Engl. J. Med., 272: 107, 1965.
Oldstone, M. B. A., Wood, W. H., and
ScHULTZ, R. a.: Reevaluation of Blood Cul-
ture as an Autopsy Procedure, Ainer. J. Clin.
Path., 43: 241, 1965.
Oldstone, M. B. A. : Hospital Acquired
Staphylococcal Disease. 1. Air Borne Trans-
mission. In press.
Osterberg, K., Aurebeck, G., Blaw, M., Chou,
S., and Nelson, E. : Electron Microscopic
Studies on Metachromatic Leukocystrophy,
Arch. Neurol., 11: 273, 1964.
Osterberg. K., Blaw, M., Kozak, P., and
Nelson, E. : Sudanophilic Leukodystrophy
and Adrenal Cortical Atrophy, Arch. Neurol..
11: 626, 1964.
ScHULTZ, R. A., Oldstone. M. B. A., and
Wood, W. H. : Reevaluation of Blood Cul-
ture as an Autopsy Procedure, Antcr. J.
Clin. Path., 43: 241, 1965.
Stauffer, J., Connor, T., Heck, A., and
Baumgardner, G. : Reversible Muscular
Atrophy in Hyperparathyroidism. (Paper
given at 16th Annual Meeting, American
Academy of Neurology, Denver, Colorado,
April 28, 1964.) Neurology, 14: 256-57, 1964
(abstract).
Wise, Goulding, Monroe and Kramer: EEG
Activation of Patients Receiving Phenothia-
zines and/or Chloradizepoxide. Accepted for
publication in .L Ncrv. Ment. Dis.
Wood. W. H.. Oldstone, M. B. .\.. and
ScHULTZ. R. .A. : Reevaluation of Blood Cul-
ture as an .Autopsy Procedure, Amcr. J. Clin.
43: 241. 1965.
Vol. .^i. No. 3
MEDICAL SCHOOL SECTION
i)ei'aktmp:nt of obstetrics
am) (jvnecoi.ogy
liKKiii. ^t. C, and Garcia. R. : Salmonella
Infection in an Ovarian Dermoid Cyst in
Pregnancy, Obstcl. Gyncc, 1964.
CoHE.v, H., MoszKowsKi, E. F., and Haskixs.
A. L. : Chiari-Frommel Syndrome, Aincr. J.
Obstct. Gyncc, March 1, 1964.
Co.\. E. F., Villa Santa. U., Ketciium. A. S.,
and MuxFORD. R. S.: Patient Evaluation for
Pelvic Exenteration. Amcr. Surg.. September,
1964.
Garcia, R., and Breiji. M. C. : Salmonella
Infection in an Ovarian Dermoid Cyst in
Pregnancy, Obstct. Cyiicc, 1964.
Garcia. R. : Histochemical Observations of
Mucins in Human Ovarian Neoplasms,
Cancer, 1964.
Haskixs, a. L. : The Reproductive Behavior
of the Adolescent Female, Bull. Sch. Med.,
Uniz'. Maryland, January, 1964.
Haskixs. A. L., Moszkowski. E. F., and
CoHE.x, H. : Chiari-Frommel Syndrome,
Amer. Obstct. Gyncc., March 1, 1964.
HaskiiXS, A. L., and Rimer, B. A. : The Hypo-
gonadal State in the Prepuberal Female,
Pacific Med. Surg., September-October, 1964.
Haskixs, A. L. ; (Method of.) Leiomyoma
(Fibroma of Uterus), Chapter: Current
Therapy, 1964.
Ketchum, a. S., Villa Santa, U., Cox, E. F.,
and MuxFORD, R. S. : Patient Evaluation for
Pelvic Exenteration, Amer. Surg., Septem-
ber, 1964.
Moszkowski. E. F., Haskixs, A. L., and
CoHEX, H. : Chiari-Frommel Syndrome,
Amer. J. Obstct. Gyncc, March 1, 1964.
MuxFORD, R. S., Ketchum, a. S., Villa
S.\xta, U., and Cox. E. F. : Patient Evalua-
tion for Pelvic Exenteration, Amer. Surg.,
September, 1964.
Rimer, B. A., and Haskixs, A. L. : The Hypo-
gonadal State in the Prepuberal Female,
Pacific Med. Surg., September-October, 1964.
ViLL.\ Sant.v. U. : Tumors of !Mesonepheric
Origin in the Female Genital Tract, Amer. J.
Obstct. Gyncc, July 1, 1964.
Villa Saxta, U.. Cox, E. F., Ketchum, A. S.,
and MuxFORD. R. S. : Patient Evaluation for
Pelvic Exenteration, Amer. Surg.. Septem-
ber, 1964.
DEPARTMENT OF OPHTHALMOLOGY
Reeves, J. : Keratopathy .Associated with
Systemic Lupus Erythematosus. Accepted
Arch. Ophth. (Chicago).
Vax Bijsterveld, O. P., and Richards, R. D. :
Artificial Drainage Tubes for Glaucoma. Ac-
cepted Amcr. J. Ophth.
\'an Bijsterveld, O. P., and Richards, R. D. :
Bacillus Infections of the Cornea. Accepted
Arch. Ophth (Chicago).
Richards, R. D., and Vax Bijsterveld, O. P.:
.\rtificial Drainage Tubes for Glaucoma. Ac-
cepted Amer. J. Ophth.
Richards, R. D. : .Artificial Devices in Glau-
coma Surgery. Accepted Eye Ear Nose Throat
Monthly.
Richards, R. D., and Vax Bijsterveld, O. P.:
Bacillus Infections of the Cornea. Accepted
Arch. Ophth. (Chicago).
DEPARTMENT OF PATHOLOGY
Arnold, J. G., Wagner, J. A., and Meyer,
P. D. : Spontaneous Posterior Fossa Hema-
toma — Unusual Complications of Hodgkin's
Disease, Bull. Sch. Med. Univ. Maryland,
50: 45-48, 1965.
AsPLEN, C. H., BoRGES, F. J., and Wood, C. :
Acute Renal Failure After Oral Cholecysto-
grapliy. Lancet, 2: 340-341, 1964.
BoRGES. F. J., AsPLEN, C. H., and Wood, C. :
Acute Renal Failure After Oral Cholecysto-
graphy, Lancet, 2: 340-341, 1964.
Goldstein-, M. N., Wagner, J. A., and Kiefer,
L. : The Effects of Radiation In Utero on
the Human Fetal Brain (Report of a Case),
Bull. Sch. Med. Univ. Maryland, 49: 56-61,
1964.
Heefner, W. a., Sorenson, G. D., and Kirk-
p.\trick, J. B. : Experimental Amyloidosis
II. Light and Electron Microscopic Observa-
tions of Liver, Amcr. J. Path, 44: 629-644,
1964.
Heefner, W. A., Sorensox', G. D., and Kirk-
patrick, J. B. : Experimental Amyloidosis,
chapter in Methods and Achievements in E.v-
perimental Pathology, Karger, A. G. Medical
Publishers, Basel — -New York.
Jordan, R., and Wagner^ J. A. : Eastern Equine
Encephalitis, Amer. J. Trap. Med., 14: 470-
474, 1965.
KiEFER, L., Goldstein, M. N., and Wagner,
J. A. : The Effects of Radiation In Utero on
Julx, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNU'ERSITV OF MARYLAND
tlie Human Fetal Brain (Report of a Case),
Bull. Sch. Med. Univ. Maryland. 49: 56-61,
1964.
KiRKPATRiCK, J. B., Heefner, W. A., and
SoRENSON, G. D. : Experimental Amyloidosis
II. Light and Electron Microscopic Observa-
tions of Liver, Amer. J. Path., 44: 629-644,
1964.
KiRKPATRicK, J. B., Heefner, W. A., and
SoRENSON, G. D. : Experimental Amyloidosis,
chapter in Methods and Achievements in E.v-
jyerimental Pathology. Karger, A. G. Medical
Publishers, Basel — New York.
Light. J. P., and Oster, W. F. : A Study of
the Clinical and Pathologic Reaction to the
Bronchographic Agent Hytrast, Amer. J.
Roentgen.. 92: 615-622, 1964.
Meyer. P. D., Wagner. J. A., and Arnold.
J. G. : Spontaneous Posterior Fossa Hema-
toma — -"Dnusual Complications of Hodgkin's
Disease, Bull. Seh. Med. Univ. Maryland.
50: 4S-48, 1965.
Novey. R., and Wisotzkey, H. M. : Spinal
Fluid Cytodiagnosis of Central Nervous Sys-
tem Malignancy (Preliminary Report), Bull.
Seh. Med. Univ. Maryland. 49: 40-43, 1964.
Oldstone, M., Wood. W. H., and Schultz,
R. B. : A Re-evaluation of Blood Culture as
an Autopsy Procedure, Amer. J. Clin. Path..
43: 241-247, 1965.
Oster. W. F., and Light. J. P.: A Study of
the Clinical and Pathologic Reaction to the
Bronchographic Agent Hytrast, Amer. J.
Roentgen, 92: 615-622, 1964.
Passen, S., and Schultz. R. B. : Use of the
Shope Papilloma \^irus-Induced Arginase as
a Biochemical Marker in Vitro. I'irology. 26:
122-126, 1965.
Reuber, M. D. : Role of the Adrenal Glands
in the Development of Lesions of the Liver
in Rats Ingesting N-2-Fluorenyldiacetamide,
/. A',7/. Cancer Inst.. 34: 587-594, 1965.
Reuber, M.D. : Development of Preneoplastic
and Neoplastic Lesions of the Liver in Male
Rats Given 0.025 Percent N-2-Fluorenyldia-
cetamide, /. Nat. Cancer Inst., 34: 697-723,
1965.
Schultz, R. B.. Oldstone. M., and Wood.
W. H. : A Re-evaluation of Blood Culture
as an Autopsy Procedure, Auicr. J. Clin.
Path.. 43: 241-247, 1965.
Schultz, R. B., and Passen, S. : L^se of the
Shope Papilloma Virus-Induced Arginase as
a Biochemical Marker in Vitro, I'irology,
26: 122-126, 1965.
Slavin, R. E., Wright. J. R., and Wagner,
J. .\. : Intracranial Aneurysm as a Cause of
Subdural Hematoma of the Posterior Fossa,
/. Neurosurg., 22: 86-89, 1965.
SoRENSON, G. D., Heefner. W. A., and Kirk-
PATRicK. J. B. : Experimental Amyloidosis II.
Light and Electron Microscopic Observations
of Liver, Amer. .1 . Path.. 44: 629-644,
1964.
SoRENSON, G. D., Heefner. W. A., and Kirk-
PATRicK. J. B. : Experimental Amyloidosis,
chapter in Methods and Achievements in Ex-
fierimcntal Pathology, Karger, A. G. Medical
Publishers, Basel — New York.
Wagner. J. A., Goldstein, M. N., and Kiefer,
L. : Tlie Effects of Radiation In Utero of the
Human Fetal Brain (Report of a Case),
Bull. Sch. Med. Univ. Maryland, 49: 56-61,
1964.
Wagner. J. A., Wright, J. R., and Slavin,
R. E. : Intracranial Aneurysm as a Cause
of Subdural Hematoma of the Posterior
Fossa, /. Neurosurg.. 22: 86-89, 1965.
Wagner. J. A., Meyer. P. D., and Arnold.
J. G. : Spontaneous Posterior Fossa Hema-
toma — L'nusual Complications of Hodgkin's
Disease, Bull. Sch. Med. Univ. Maryland.
50: 45-48, 1965. April
\\'ai',ner. J. .-\., and Jordan. R. : Eastern Equine
Encephalitis, Amer. .1. Trot>. Med.. 14: 470-
474. 1965.
Wisotzkey. H. M., and Novey. R. : Spinal
Fluid Cytodiagnosis of Central Nervous
System Malignancy ( Preliminary Report ) ,
Bull. Sch. Med. Univ. Maryland. 49: 40-43,
1964.
Wood, C. : Closed Renal Biopsy in Adults, Bull.
Sch. Med. Univ. Maryland. 13: 61-62, 1964.
Wood. C, Asplen. C. H., and Borges, J. J.:
Acute Renal Failure After Oral Cholecysto-
graphy, Lancet, 2: 340-341, 1964.
Wood, W. H., Oldstone. M., and Schultz,
R. B.: A Re-evaluation of Blood Cultures as
an Autopsy Procedure. .4mer. J. Clin. Path..
43: 241-247. 1965.
Wright, J. R., Wagner. J. A., and Slavin.
R. E. : Intracranial .Aneurysm as a Cause of
Subdural Hematoma of the Posterior Fossa,
/. Neuro.uirg.. 22: 86-89, 1965.
Vol. .^1. No. 3
MF.niCAL SCHOOL SECTION
DEl'AKTMENT OF I'EDIATRICS
Bessma.v, S. p., and Good. T. A.: Determina-
tion ol Glucosamine and Galactosamine Using
Borate Buffers for Modification of Elson-
Morgan and Morgan-Elson Reactions, .-Iiiti.
liiocUcm. Exp. Med.. 9: 253, 196-1.
Bessmax. S. p., Skolnik. S. J., McAslan,
T. C. and Helrich, M. : Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 771, 1964.
BESsifAN, S. P., ToYODA, M., and DeSchepper,
P. U. : A Requirement for Carbohydrate
Metabolism for the Stinmlation of Amino Acid
Incorporation into Protein by Insulin, /. Biol.
Chem., 240: 5006, 1965.
Bessmax, S. p., and Hammel, C. L. : The
Control of Hemoglobin Synthesis by Oxygen
Tension in a Cell-Free System, Arch. Bio-
chcin.. 1955. In press.
Bess-Nfax. S. p.: Phenylketonuria, Med. Sci.,
1965. In press.
Bessmax, S. P. : The , Anesthetic Form of
Gamma-Hydroxybutyrate in Brain. Ab-
stracts Sixth International Congress of Bio-
chemistry, New York City, July, 1964.
Bessmax, S. P. and DeSchepper, P. J. : Glu-
cose Requirement for Insulin Effect in Pro-
tein Synthesis, Fed. Proc., 24: 576, 1965.
Bessman, S. P., and Hammel, C. L. : Hemo-
globin Synthesis in Avian Erythrocytes, /.
Biol. Chem., 239: 2228, 1964.
Bessmax, S. P., and Hammel, C. L. : The
Kinetics of the Oxygen Control of Hemo-
globin Synthesis, Arch. Biochcm., 110: 622,
1965.
Bradley, J. E. : Parents Acceptance of Mon-
golism, Child & Family, 4: 55-62, 1964.
Bradley, J. E. : Consultant's Comment, Curr.
Med. Dig.. 32: 420, 1965.
Bradley, J. E., and Frazier, T. : Blood Lead
and Socio-economic Status. Submitted to
Public Health Rep.
Clemmens, R. L. : Obscure Causes of School
Failure — A Pediatric Viewpoint, Bull. Orion
Soc, 14: 32-39, 1964.
Clemmexs, R. L., and Glaser, K. : School
Failure, Pediatrics, 35: 128-141, 1965.
Clemmens, R. I. : Minimal Brain Damage.
Historical Perspectives in Mental Retardation
During the Decade 1954-1964. U. S. Dcpt.
Health Ediic. iVelfarc Child. Bur., 87-91,
1964.
Cross, E. R., and Gortex. M. K. : Iron
Metabolism in Premature Infants II. Pre-
vention of Iron Deficiency, /. Pediat., 64:
509, 1964.
DeSciiepper, p. J., Toyoda. M., and Bessman,
S. P. : .\ Requirement for Carbohydrate Me-
tabolism for the .Stimulation of Amino Acid
Incorporation into Protein by Insulin, /. Biol.
Chem.. 240: 5006, 1965.
DeSciiepper. P. J., and Bessmax, S. P.: Glu-
cose Requirement for Insulin Effect on Pro-
tein Synthesis, Fed. Proc, 24: 576, 1965.
Frazier, T., and Bradley, J. E. : Blood Lead
and Socio-economic Status. Submitted to
Public Health Rep.
Glaser, K., and Clemmexs. R. L. : Scliool
Failure, Pediatrics, 35: 128-141, 1965.
Glaser, K. : Attempted Suicide in Children and
Adolescents : Psychodynamic Observations,
Amcr. J. Psychothcr., 19: 220-227, 1965.
Glaser, K. : Suicide in Children and Adoles-
cents. Acting Out: Theoretical and Clinical
Aspects, S. L. Weissman, and L. E. Abt,
editors. To be published in 1965 by Grune and
Stratton, N. Y.
Glaser, K. : Book Review : A History of the
Care and Study of the Mentally Retarded by
Leo Kanner. Amer. J. Psychothcr., 18: 538,
1964
Good. T. A., and Bessman, S. P. : Determina-
tion of Glucosamine and Galactosamine Using
Borate Buffers for Modfiication of Elson-
Morgan and Morgan-EIson Reactions, Ann.
Biochem. Exp. Med., 9: 253, 1964.
Good, T. A., and Schulte, C. J. A.: Acute
Methsuximide (Celontin) Intoxication. Sub-
mitted to the /. Pediat.
GoRTEN, M. K. : Detection of Xeonatal Jaundice,
GP, 29: 101, 1964.
i-GoRTEN, M. K. and Cross, E. R. : Iron
Metabolism in Premature Infants II. Pre-
vention of Iron Deficiency, /. Pediat., 64:
509, 1964.
GoRTEN, M. K., Hepner, R. and Workman,
J. B. : Iron Metabolism in Premature Infants
I. Absorption and Utilization of Iron as
Measured by Isotope Studies, Blood, 23: 551,
1964 (abstract).
GoRTEN, M. K. : Utilization of Iron for Growth
by Small Premature Infants, /. Pediat., 65:
1130, 1964 (abstract).
Gortex, M. K. : Detection of Xeonatal Jaundice,
Mod. Med., 32: 136, 1964.
July. 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
GoRTEN, M. K., and Hefner, R. : Iron Balance
. in Small Premature Infants, Southern Med.
J., 57: 1462, 1964.
GoRTEN, M. K. : Iron Metabolism in Premature
Infants III. Utilization of Iron as Related
. to Growth in Low Birth Weight Infants,
. Amer. J . Clin. Ntitr. In press.
Hammel, C. L., and Bessman, S. P. : The
Control of Hemoglobin Synthesis by Oxygen
Tension in a Cell-Free System, Arch. Bio-
chem., 1965. In press.
Hammel, C. L., and Bessman, S. P. : Hemo-
. globin Synthesis in Avian Erythrocytes, /.
Biol. Ghent., 239: 2228, 1964.
Hammel, C. L., and Bessman, S. P. : The
Kinetics of the Oxygen Control of Hemo-
globin Synthesis, Arch. Biochem., 110: 622,
1965.
Helrich, M., McAslan, T. C, Skolnik, S. J.,
and Bessman, S. P. : Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 771, 1964.
Hepner, R., Gorten, M. K., and Workman.
• J. B. : Iron Metabolism in Premature Infants
I. Absorption and LItilization of Iron as
Measured by Isotope Studies. Blood. 23: 551,
1964 (abstract).
Hefner, R., and Gorten, J. K. : Iron Balance
in Small Premature Infants, Southern Med.
J.. 57: 1462, 1964.
Hefner, W. R. : Revision of Care of the
Premature, Current Therapy, edited by Conn.
Lentz, G. a., Jr. : Lead article for UCP of
Baltimore publication, 53 Minutes.
McAslan, T. C, Helrich, M., Skolnik, S. J.,
and Bessman, S. P. : Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 771, 1964.
Patron, L., and Walker, S. H. : Unclassi-
fied Mycobacterial Infections in Children,
Amcr. Dis. Child., Nov., 1964.
Patron. L., and Walker. S. H. : Colistin
Therapy in Infants and Children, Amer. J.
Dis. Child., March, 1965.
Rubenstein, H. J., and Weaver, K. H. :
Monozygotic Twins Concordant for Ven-
tricular Septal Defect, Anicr. J. Cardiol.,
. 15: 386, 1965.
ScHERLis, Sidnev : Stress, Trauma and Heart
Disease. Cardiac Section, Cyclof>cdia of Medi-
cine. F. A. Davis Co., Philadelphia, June,
1965.
ScHULTE, C. J. A., and Good, T. A.: Acute
Methsu.ximide (Celontin) Intoxication. Sub-
mitted to the /. Pcdiat.
Skolnik, S. J., McAslan, T. C, Helrich, M.,
and Bessman, S. P. : Correlation of Blood
Levels of 4-Hydroxybutyrate with State of
Consciousness, Anesthesiology, 25: 771, 1964.
Toyoda, M., DeSchepper, P. U., and Bessman,
S. P. : A Requirement for Carbohydrate
Metabolism for the Stimulation of Amino
Acid Incorporation into Protein by Insulin,
/. Biol. Chem., 240: 5006, 1965.
Walker, S. H., and Patron, L. : Unclassified
Mycobacterial Infections in Children, Amer.
J. Dis. Child., Nov., 1964.
Walker, S. H., and Patron, L. : Colistin
Therapy in Infants and Children, Anicr. J.
Dis. Child., March, 1965.
Weaver, K. H. : The Heart and Acute Glomer-
ulonephritis, Maryland Med. J., 13: 131, 1964.
Weaver, K. H., and Rubenstein, H. J. : Mono-
zygotic Twins Concordant for Ventricular
Septal Defect. Amer. J. Cardiol, 15: 386,
1965.
Workman, J. B., Hepner. R., and Gortex.
M. K. : Iron Metabolism in Premature In-
fants I. Absorption and L'tilization of Iron as
Measured by Isotope Studies, Blood, 23: 551,
1964 (abstract).
DEPARTMENT OF PHARMACOLOGY
Blake, D. .•\., and Rozma.v, R. S. : Metabolism
of Fluoromar-C'' in Mice, Fed. Proc.. 24:
269, 1965.
Bruade, Monique C, and Krantz, J. C, Jr. :
Toxicity and Convulsive Activity of a Series
of Theophylline Derivatives, To.ric. Apfl.
Pharmacol., 7: March, 1965.
Bruade, Monique C, and Krantz, J. C, Jr.:
Toxicity and Convulsive Activity of a Series
of Theophylline Derivatives, To.xic. Appl.
Pharmacol., 7: March, 1965.
Bruade, Monique C, and Krantz, J. C, Jr. :
Rationale of the Use of Fluorinated Hydro-
carbons and Ethers as Volatile Anesthetic
Agents, Anesth. Analg., 44: May-June 1965.
Brliade, Monique C, and Krantz, J. C, Jr.:
The New Law : Drugs, Drug Houses and
Drug Officials, Milit. Med.
Bltrgison, R. M. : Cancer Research Supple-
ment: Vol. 24, No. 6 (July, 1964), pp. 963,
990-991, 1000; Vol. 24, No. 3 (April. 1964),
pp. 558-559; 633-634; Vol. 24, No. 11 ( De-
;•<>/. 51. No.
MEDICAL SCHOOL SECTION
cembcr. 1964). pp. 1112. Vol. 25, No. 1
(January, 1965), pp. 146-147; 152; 164-165.
C.\RR, C. J., and Kraxtz, J. C, Jr. : Pharma-
cologic Principles of Medical Practice, 6th
Ed.. 1965. Williams and Wilkins Co., Balti-
more.
C.\scoRBi, H. F., RuDO, F. G. : The Anesthetic
Index and the Potency of Volatile Anesthetics,
Aiieslh. Analg., 43: iZi, 1964.
C.\scoRBi, H. F., RuDO, F. G. : The Potency of
Methoxyflurane and Halothane, Ancsth.
Analg., 43: 163, 1964.
Davisox, C, and Rozm.vx. R. S. : Studies on the
Reachion Products of Bis-B-Chloroethyl Sul-
fide-S'*-' with Cellular Polynucleotides and
Xucleic Acid Bases, Bull. Sch. Med. Univ.
Maryland, 50: 5, 1965.
DuRiTZ, G., and Truitt, E. B., Jr. : A Rapid
Method for the Simultaneous Determination
of Acetaldehyde and Ethanol in Blood using
Gas Chroniatograph}', Quart. J. Stud. Alcohol,
25: 498-510, 1964.
DcRiTZ, G., and Truitt, E. E., Jr. : The Role
of Acetaldehyde in the Actions of Ethanol in
Biochemical Factors in Alcoholism by R. P.
Maickel and Brodie, editors, Pergamon Press,
X. V.
Alternate Glycolytic Pathways in Brain : A
Comparison Between the Action of Artificial
Electron Acceptors and Electrical Stimulation.
J. J. O'Neill.
A Technique for the Study of Electrically
Stimulated Tissue with 14C — labelled Sub-
strates. J. J. O'Neill.
Kraxtz, J. C, Jr., Terrell, R., Rozm-an, R. S. :
Anesthesia LXVII : Indoklon, a New Psychi-
atric Drug, and Its Sulfur Analog, Bull.
Sch. Med. Univ. Maryland, 49: 36 (1964).
Kr.vxtz, J. C., Jr., and RuDo, F. G. : Chapter 12,
Fluorinated Anesthetics for Hefter-Heuber
Handbuch.
Kraxtz, J. C, Jr., and Rudo, F. G. : Experi-
mentellen Pharmakologie — Pharmacology of
Fluorine edited by Frank A. Smith 1965. In
press.
Kraxtz, J. C, Jr., and Rudo, F. G. : The
Laboratory Animal and New Drugs, Bull.
Sch. Med. Univ. Maryland, 49: Jan., 1964.
Kraxtz, J. C, Jr., and Rudo, F. G. : The
Pharmacology of Tranquilizing Agents, /.
Kcuropsychiat., 5 :
Kraxtz, J. C, Jr., and Carr, C. J. : Pharma-
cologic Principles of Medical Practice, 6th Ed.,
1965. Wlliams and Wilkins Co., Baltimore.
Morgax, a. M., and Truitt, E. B. : Gastro-
intestinal Factors in Aspirin .Absorption, /.
Pharm. Sci., 53: 129-134, 1964.
Morgan, A. M., and Truitt, E. B., Jr.: Evalua-
tion of .Acetylsalicylic Acid Esterase in
Aspirin Metabolism. An Interspecies Com-
parison. Submitted for pulilication Biochem.
Pharmacol.. 1965.
Mlsseh, R. O., and Shuukagel, E. : (.Assisting
in the preparation of the manuscript) :
Modern Pharmacology and Therapeutics, 3rd
Ed.. Macmillan, New York. In press.
Needlemax, Philip, and Kraxtz, J. C, Jr.:
The Biotransformation of Nitroglycerin,
Biochem. Pharmacol., 14: 1965. In press.
RozMAX, R. S., Terrell, R., and Kraxtz, J. C,
Jr. : Anesthesia LXVII : Indoklon, a New
Psychiatric Drug, and its Sulfur Analog,
Bull. Sch. Med. Univ. Maryland, 49: 36,
1964.
Roz.MAX, R. S. : The ResiJonsc of the Hema-
topoietic System to Drugs. Chap. 45, Pharma-
cologic Principles of Medical Practice, 6th
Ed., by J. C. Krantz, Jr., and C. J. Carr,
Williams and Wilkins, Baltimore, 1965.
RozMAN, R. S., and Blake, D. A.: Metabolism
of Fluoromar-Ci-* in Mice, Fed. Proc, 24:
269, 1965.
RozMAN, R. S., and Davisox-, C. : Studies on
the Reaction Products of Bis-B-Chloroethyl
Sulfide-S^^ w'ith Cellular Polynucleotides and
Nucleic Acid Bases, Bull. Sch. Med. Univ.
Maryland, 50: 5, 1965.
Rudo. F. G., and Cascorbi. H. F. : The Anes-
thetic Index and the Potency of Volatile
Anesthetics, Anesth. Analg., 43: 333, 1964.
Rudo, F. G., and Cascorbi, H. F. : The Potency
of Methoxyflurane and Halothane, Anesth.
Analg., 43: 163, 1964.
Rudo, F. G., and Krantz, J. C. Jr. : The Labo-
ratory Animal and New Drugs, Bull. Sch.
Med. Univ. Maryland, 49: Jan., 1964.
Shubkagel, E., and Musser, R. D. : (Assisting
in the preparation of the manuscript) :
Modern Pharmacology and Therapeutics, 3rd
Ed., Macmillan, New York. In press.
Terrell, R., Rozman, R. S., and Krantz, J. C,
Jr. : Anesthesia LXVII : Indoklon, a New
Psychiatric Drug, and its Sulfur Analog,
Bull. Sch. Med. Univ. Maryland, 49: 36, 1964.
Truitt, E. B., and Morgan, A. M. : Gastro-
intestinal Factors in Aspirin Absorption, /.
Pharm. Sci., 53: 129-134, 1964.
July, 1966
BULLETIX OF THE SCHOOL OF MEDICINE. VXIi-ERSITY OF MARYLAND
Truitt, E. B.. Jr., and Duritz, G. : A Rapid
Method for the Simultaneous Determination
of Acetaldehyde and Ethanol in Blood Using
Gas Chromatography, Quart. J. Stud. Alco-
hol, 25: 498-510, 1964.
Truitt, E. B., Jr.: The Xanthines. Chap. 28,
PJianmicology in Medicine. J. R. DiPalma,
editor. McGraw-Hill, New York, 1965.
Truitt, E. B., Jr., and Morgan, A. M. : Evalu-
ation of Acetylsalicylic Acid Esterase in
Aspirin Metabolism. An Interspecies Com-
parison. Submitted for publication Biochcin.
Pharmacol.. 1965.
Tkuitt. E. B., Jr.. and Duritz, G. : The Role
of Acetaldehyde in the Actions of Ethanol in
Biochemical Factors in Alcoholism by R. P.
Maickel, and Brodie, editors, Pergamon
Press, N. Y.
Alternate Glycolytic Pathways in Brain : A
Comparison Between the Action of Artificial
Electron Acceptors and Electrical Stimula-
tion. J. J. O'Neill.
A Technique for the Study of Electrically
Stimulated Tissue with 14C — Labeled Sub-
strates. J.J. O'Neill.
DEPARTMENT OF PHYSIOLOGY
Adelman, W. J., Jr., and Fok, Y. B. : Internally
Perfused Squid Axons Studied Under Volt-
age Clamp Conditions, I. Method. /. Cell.
Comp. Physiol., 64: 423-428, 1964.
Adelman, W. J., Jr., Dyro, F. M., and Senft,
J. : Long Duration Responses Obtained from
Internally Perfused Axons, /. Gen. Physiol.,
48: 1-9, 1965.
Adelman, W. J., Jr. : Bioelectricity, Encyclo-
pedia of Science and Technology, 1965 Year-
book, McGraw-Hill, New York.
Adelmax, \V. J., Jr., and Dyro, F. M. : Re-
lation of Hyperpolarizing Response to Po-
tassium Conductance in Internally Perfused
Squid Axons, Bio. Bull., 127: 361, 1964.
Adelman, W. J., Jr., Dyro, F. M., and Senft,
J. : Spontaneous Cardiac-Like Repetitive Re-
sponses from Internally Perfused Squid
Axons, Biophys. Soc. Abs., 9th Annual Meet-
ing, WB5, 1965.
Adelman. \\\ J., Jr., Senft, J., and Dyro.
F, M. : Long Duration Action Potentials from
the Internally Perfused Squid Axon, Fed.
I'roc. 24: 584, 1965.
Adelman, W. J., and Taylor, R. E. : Effects
of Replacement of External Sodium Chloride
with Sucrose on Membrane Currents of the
Squid Giant Axon, Biopliys. /.. 4: 451-463,
1964.
Adelman, W. J., Jr. and Gilbert, D. L. :
Internally Perfused Squid Axons Studied
Under Voltage Clamp Conditions. I. Method,
/. Cell. Comp. Physiol., 64: 423-428, 1964.
Barraclough, C. a., Yrarrazaval, S., and
Hatton, R. : A Possible Hypothalamic Site
of Action of Progesterone in the Facilitation
of Ovulation in the Rat, Endocrinol., 75: 838,
1964.
Barraclough. C. A.: Modifications in Repro-
ductive Function after Exposure to Hor-
mones during the Pre- and Early Postnatal
Period. Chapter 19 in Neuroendoerinology.
edited by W. Ganong and L. Martini, Aca-
demic Press, N. Y., 1965.
Blake, 'W'. D., and Jurf, A. M. : Denervation
Diuresis on Free Water Reabsorption in Dog
and Rabbit, Fed. Proc., 24: 642, 1965.
Dyro, F. M., Adelman, W. J., Jr., and Senft,
J. : Long Duration Responses Obtained from
Internally Perfused Axons, /. Gen. Physiol.,
48: 1-9, 1965.
Dyro, F. M., and Adelman, 'W. J., Jr. : Re-
lation of Hyperpolarizing Response to Po-
tassium Conductance in Internally Perfused
Squid Axons, Biol. Bull., 127: 361, 1964.
Dyro, F. M., Adelman, W. J., Jr., and Senft.
J. : Spontaneous Cardiac-Like Repetitive Re-
sponses from Internally Perfused Squid
Axons, Biophys. Soc. Abs., 9th Annual Meet-
ing, ■WB5, 1965.
Dyro, F. M., Adelman, W. J., Jr., and Senft,
J. : Long Duration Action Potentials from the
Internally Perfused Squid Axon, Fed.. Proc.,
24: 584,1965.
Fok, Y. B., and Adelman. W. J., Jr.: In-
ternally Perfused Squid Axons Studies Under
Voltage Clamp Conditions. I. Method, /.
Cell. Comp. Physiol., 64: 423-428, 1964.
Gilbert. D. L., and Adelman, W. J., Jr. : In-
ternally Perfused Squid Axons Studied
LInder Voltage Clamp Conditions. I. Method,
/. Cell. Comp. Physiol., 64: 423-428, 1964.
Glaser, E. M., and Van der Loos : A Senii-
Automatic Computer Microscope for the
Analysis of Neurone Morphology, I.E.E.E.
Trans, on Biomed. Eng., BME. 12: 22-31,
1965.
Glaser, E. M. : Stimulator for Complex Acous-
tic 'Waveforms, J. Acoust. Soc. Anier., 36:
1288-1291, 1964.
/■<)/. 51, Xo. 3
MEniCAI. SCHOOL SECTION
IIattax. R.. Vakrazaval. S.. and Bakra-
L LOUGH. C. A.: A Possible Hypothalamic Site
of Action of Progesterone in the Facilitation
of Oviilation in the Rat, IliidocriiioL. 75: 838,
1964.
JiRF. A. X.. and Blake. W'. D. : Denervation
Diuresis on Free Water Keabsorption in Dog
and Rabbit. Fed. Proc. 24: 642. 1965.
PiXTER. G. (i., and Siiohet. J. I,.; Derivation
of Partial Differential Equations Utilized in
a Model Describing the Xa Concentration
Profile in the Renal Medulla, Xaliirr. 204:
689-690, 1964.
Pinter, G. G. : Distribution of F^l Albumin
and P-' Chyloniicra in Renal Tissue. Pro-
ceedings of the International Symposium on
the Preparation and Bio-Medical Application
of Labeled Molecules, Venice, 1964 ; Euratom,
1965.
Sexft. J. DvRO. F. M., and Adelmax, W. J.,
Jr. : Long Duration Responses Obtained from
Internally Perfused Axons, /. Gen. Physiol.,
58: 1-9, 1965, part 2.
Sexft, J., Dvro. F. M., and Adeljian, W. J.,
Jr. : Spontaneous Cardiac-Like Repetitive Re-
sponses from Internally Perfused Squid
Axons, Biophys. Soc. Abs., 9th Annual fleet-
ing, WB5, 1965.
Sexft, J., Adelmax, W. J., Jr., and Dyro,
F. M. : Long Duration Action Potentials from
the Internally Perfused Squid Axon, Fed.
Proc., 24: 584, 1965.
Shohet, J. L., and Pinter, G. G. : Derivation
of Partial Differential Equations Utilized in
a ^Model Describing the X'a Concentration
Profile in the Renal Medulla, Xatiirc, 204:
689-690, 1964.
Taylor, R. E., and Adelmax, W. J. : Effects
of Replacement of External Sodium Chloride
with Sucrose on Membrane Currents of the
Squid Giant Axon, Biof<hys. J.. 4: 451-463,
1964.
^'AN DER Loos, and Glaser, E. M. : A Semi-
Automatic Computer Microscope for the
Analysis of Neurone Morphology, I.E.E.E.
Trans, on Biomed. Eng., BME, 12: 22-31,
1965.
Yrarraz.wal, S., Barraclough, C. a., and
Hattox, R. : A Possible Hypothalamic Site
of Action of Progesterone in the Facilitation
of Ovulation in the Rat, Endocrinol., 75: 838,
1964.
DEPARTMENT OF PREVENTIVE
MEDICINE AND REHABILITATION
Bartiiel. D. W., and Maiioxey, F. I.: The
Barthel Index, Maryland Med. /., Feb., 1965.
ExTwisLE. G., and Reinke, W. A.: Statistical
h'valuation of Medical Information, Bull.
Srh. .!/,■</. Uiiiz: Maryland, 50: 32, .\pril,
1965.
Jaxer. J. L., Vazquez, J., Paniacus, M. E.,
and Tavtabak, J.: Medical and Psychological
Sequelae of Surgical Sterilization of Women,
Awcr. J. Obstct. Gyncc, 90: 4, 1964.
Mahoney, F. L, and Bartiiel, D. W. : The
Barthel Index, Maryland Med. J., Feb., 1965.
Mahoxev, F. I. : Dr. Maboney's pamphlet,
U/' and Around, published last year by the
U. S. Department of Health, Education and
Welfare, has been reproduced in a smaller
size by the American Heart Association.
Paniacus, M. E., Taytabk, J., Janer, J. L.,
and Vazquez, J. : Medical and Psychological
Sequelae of Surgical Sterilization of Women,
Amer. J. Obstet Gyncc, 90: 4, 1964.
Reinke, W. A., and Entwisle, G. : Statistical
Evaluation of Medical Information, Bull. Sch.
Med. Univ. Maryland, 50: 32, 1965.
Richardson, P. F. : Problems in Rehabilitation,
Maryland Med. J., October, 1964.
Richardson, P. F. : Physical Therapy in
Medical Practice, Maryland Med. J., June,
1965.
Taytabk, J., Janer, J. L., Vazquez, J., and
Paniagus, M. E. : Medical and Psychological
Sequelae of Surgical Sterilization of Women,
Amer. J. Obstet. Gynec., 90: 4, 964.
Vazquez, J., Paniacus, M. E., Taytabk, J.,
and Janer, J. L. : Medical and Psychological
Sequelae of Surgical Sterilization of Women,
Amer. J. Obstet. Gynec., 90: 4, 1964.
DEPARTMENT OF PSYCHIATRY
Ames, L. L., and Findley, J. D. : A Note on
Time Out from Avoidance with the Chim-
panzee, /. Exp. Anal. Behav., 1965. In press.
Aronson, H., and Overall, B.: Treatment
Expectations of Patients in Two Social
Classes. In press.
Aronson, H., and 0\'erall, B. : Expectations
of Psychotherapy in Patients of Lower Socio-
economic Class, reprinted in Mental Health
of the Poor, edited by Riessman, Cohen, and
Juh, 1966
BULLETIN OF THE SCHOOL OF MEDICINE. VNIVERSITY OF MARYLAND
Pearl, the Free Press of Glencoe, Collier-
Macmillan Ltd., London, 1964.
Aronson, H., and Weintraub, W. : The Appli-
cation of Verbal Behavior Analysis to the
Study of Psychological Defense Mechanisms.
II : Speech Pattern Associated with Im-
pulsive Behavior, /. Nerv. Mcnt. Dis., 139:
July, 1964.
Aronson, H., and Weintraub, W. : The Appli-
cation of Verbal Behavior Analysis to the
Study of Psychological Defense Mechanisms.
Ill : Speech Pattern Associated with De-
lusional Behavior. Accepted for publication.
Aronson, H., and Young, I. : Treatment Ex-
pectations of Patients in Two Social Classes,
/. of Social Work. In press.
Bahn, a., Gorwitz, K., Klee. G. D., Kramer,
M., and Tuerk, I. : Psychiatric Services Re-
ceived by Residents of an Entire State Dur-
ing a One Year Period (Maryland Psychiatric
Case Register : Analysis of the First Year's
Experience), Public Health Rep. In press.
Baldwin, R., Mackie, J. B., and Kexxv, T. :
Incidence of Minimal Brain Injury in
Adopted Children, Maryland J. Med. In press.
Balis, G. U., and Monroe, R. R. : The Pharma-
cology of Chloralose : A Review, Psycho-
pharmacologia (Berlin), 6: 1-30, 1964.
Bass, B., and Motchar, J. : Experiences in
Group Counselling with Aging Men in an
Out-patient Setting, Geriatrics.
Beck, H. C, and Mackie, J. B. : Personality
Organization and Brain Damage, Psychiat.
Spectator, 1: Sept. 1964.
Beck, H. C, and Mackie, J. B. : Age, Intelli-
gence and CFF, Psychomotor Skills. In press.
BowEN, M. : Intrafamily Dynamics in Emotional
Illness, chapter in Family, Church, and Com-
munity, edited by A. D'Agostino, M.D., P. J.
Kennedy and Sons, New York, March, 1965.
BowEN, M. : Family Psychotherapy in the
Hospital and in Private Practice, chapter in
Intensive Family Therapy, edited by Nagy
and Framo, Harper and Row, New York,
May, 1965.
BowEN, M. : Theoretical Rationale of Family
Psychotherapy, presented at a Symposium of
Family Psychotherapy, Marquette University.
Milwaukee, Wisconsin, October, 1964. (In
press as a chapter in a book containing the
papers from the Marquette Symposium to be
published by Science and Behavior Books,
Inc.)
BowEN, M. : The Family as a LTnitary Psycho-
logical System, presented at a Family Sym-
posium, Group for the Advancement of Psy-
chiatry, Philadelphia, April 19, 1964. (In
press as a GAP publication.)
Brady, J. V., and Findley, J. D. : Facilitation
of Large Fi.xed-Ratio Performance by L'se
of Conditioned Reinforcement, /. E.vp. Anal.
Behav., 8: 1964.
Braude, M. C, and Kraxtz, J. C, Jr. : Toxicity
and Convulsive Activity of a Series of Theo-
phylline Derivatives, Toxic. Appl. Pharmacol.,
7: 291-300, 1965.
Braude, M. C, and Monroe, R. R. : Neuro- and
Psychopharmacologic Studies of Alphaglu-
cochloralose ( AGC) and Dimethylsulfoxide
(IMSO), Fed. Proc, 24: 390, 1965.
Braude, M. C, and Monroe, R. R. : Dimethyl-
sulfoxide : Solubilizing and Interactive
Effects with Alphaglucochloralose. In press.
Brody, E. B. : The Clinical Nurse Specialist in
Nursing Administration, /. Psychiat. Nurs.,
June, 1964.
Brodv, E. B. : Some Conceptual and Methodo-
logical Issues Involved in Research on Society,
Culture and Mental Illness, /. Nerv. Mcnt.
Dis., 139: 62-74, 1964.
Brody, E. B. : Summary and Charge. Proceed-
ing, Maryland Conference on Mental Health,
Fall, 1964. Published April, 1965.
Brody, E. B. ; Treatment of an Adult Thumb-
sucker : In Column on Clinical Advise,
J.A.M.A., 189: 971, 1964.
Brody, E. B. : Book Review : Segregation and
Mental Health, edited by M. Grossack,
Springer, New York, 1963, Psychiatry, 28:
196-197, 1965.
Brody, E. P. : Psychiatry and the Social Order,
Anter. J. Psychiat. In press.
Brody, E. B. : Psychiatry and Prejudice,
chapter in American Handbook of Psychiatry,
Supplement, edited by S. Arieti. In press.
Brody, E. B. : Staffing Patterns, chapter in
The Future of Psychiatry, edited by M. Kauf-
man, International University Press. In press.
Brody, E. B. : Book Review : The Universal
Experience of Adolescence, edited by N. Kiel],
International L'niversity Press, New York,
1964, ./. Nerz: Ment. Dis. In press.
Brody, E. B. : Book Review : The Psychoana-
lytic Study of the Child, Vol. XVIII, Inter-
national University Press, New York, 1964,
/. A'erv. Mcnt. Dis. In press.
Vol. .^i. No. 3
MEDICAL SCHOOL SECTIOX
Browx, G. p.: The Pctliatrician ami Psyclioso-
iiiatic Medicine, /. .Vu/. Mcil. Ass.. 57:
143, 1965.
liKowN, R., ScHLEiFER. C. B., and Derbyshire,
R. : Symptoms and Symptom Change in
Hospitalized Negro and White Mental
I'atients, /. Human Behavior. In press.
L'l KMMENS, R. L. : Obscnre Causes of School
Failure — A Pediatric Viewpoint, Bull. Orton
Soc, 14: 32-39, 1964.
Ci.K.MMENS, R. L., and Glaser, K. : School
I'ailure, Pediatrics. 35: 128-141, 1965.
Cr.EMMF.N?. R. L. : Minimal Brain Damage,
chapter in Historical Perspectives in Mental
Retardation During the Decade 1954-1964,
U. S. Department of Health, Education and
Welfare, Children's Bureau, 87-91, 1964.
CnNXOK. T. B., LovicE. H., HuFFER, V., and
.^coTT. W. H. : Psychological Studies of
.\dult Male Patients with Sexual Infantilism
Before and After Androgen Therapy, Ann.
Intern. Med.. 255-368, 1964
.\ddendum to above article appearing as Letter
to the Editor, Ann. Intern. Med., Dec, 1964.
Book Review : Psychobiological Approaches
to Social Behavior, by P. H. Leiderman and
D. Shapiro, Stanford University Press, Curr.
Med. Dig., 32: 398, 1965.
I)ALE. R., and Monroe, R. R. : Chlordiozepo.x-
ide in the Treatment of Patients W'ith Acti-
vated EEG's. In press.
Derbyshire, R. L. : The Uncompleted American
Xegro Family, /. Human Relations, 1965.
In press.
Derbyshire, R. L. ; United States Negro
Identity Conflict, Int. J. Soc. Psychiat., 1965.
In press.
Derbyshire, R. L. : The Social Control Role
of the Police in Urban Racial Conflict, Mary-
land Magazine, 1965. In Press.
Derbyshire, R. L., Schleifer, C. B., and
Brow.x, R. : Symptoms and Symptom Change
in Hospitalized Negro and White Mental
Patients, /. Human Behav. In press.
Derbyshire, R. L., Schleifer, C. B., and
Browx, R. : Desegregation of a State Mental
Hospital for Negroes : A Study of StaflF
Attitudes, Amcr. J. Psychiat., 121: April,
1965.
Eichler, M. : Book Review : Drugs in Psycho-
analysis and Psychotherapy, by Mortimer
Ostow, Basic Books, New York, /. Nerv.
Mcnt. Dis., 139: 591-592, 1964.
Eichler, M., and Normax, J.: Repeated Use
of the Bender Gestalt Test in a Study of
an Induced To.xic State, Perceptual and
Motor Skills, 1965. In press.
Ferster, C. B., Findley, J. D., and Leve.xson,
P. K. : A Method for Training Unrestrained
Primates to Receive Drug Injections, /. E.vp.
Anal. Behav., 7, 1964,
FiNDLEY, J, D. : Programmed Environments for
Experimental Analysis of Human Behavior,
chapter in Operant Behavior and Psychology,
edited by W. Honig, Appleton-Century-
Crofts, New York, 1964.
FiNDLEY, J. D., and Brady, J. V. : Facilitation of
Large Fixed-Ratio Performance by Use of
Conditional Reinforcement, /. Exp. Anal.
Behav., 8, 1964.
FiNDLEY, J. D., Zimmerman, J., and Schuster,
C. : Second-Order Avoidance Behavior Under
24-Hour Control Experiments, 1964. In press.
FiNDLEY, J. D., and Ames, L. L. : A Note
on Time Out from Avoidance with the
Chimpanzee, /. E.rp. Anal. Behav., 1965. In
press.
FiNDLEY, J. D., Levenson, P. K., and Ferster,
C. B. : A Method for Training Unrestrained
Primates to Receive Drug Injections, /. E.vp.
Anal. Behav., 7, 1964.
Fowler, H. B., and Sata, L. S. : Clinic Staff
Changes Create Community Anxiety, Ment.
Hasp.. 612-617. Nov., 1964.
Gilbert, M. S. W., and Tuerk, I. : Analysis of
an Open-Ended Group for Alcoholic Patients.
Glaser, K., and Clemmens, R. L. : School Fail-
ure, Pediatrics, 35: 128-141, 1965.
GoRWiTz, K., Klee, G. D., Kramer, M., Tuerk,
I., and Bahn, A. : Psychiatric Services Re-
ceived by Residents of an Entire State Dur-
ing a One Year Period. Maryland Psychiatric
Case Register : Analysis of the First Year's
Experience, Public Health Rep. In press.
Goulding, R., Monroe, R. R., Kramer, M.,
and Wise, S. : EEG Activation of Patients
Receiving Phenothiazines and/or Chlordia-
zepoxide. In press.
Gross, A. : Training of Clinical Psychologists :
A Mental Hospital Viewpoint, Proceedings
of the Conference on Professional Preparation
of Clinical Psychologists, Maryland Depart-
ment of Mental Hygiene, 1964.
Guttmacher, M. : Critique : Views of Thomas
Szasz on Legal Psychiatry, Arch. Gen.
Psychiat., 10: March, 1964.
July, 1966
BULLETIN OF THE SCHOOL OF MEDICINE, UNIJ'ERSITV OF MARYLAND
GuTTMACHER, M. : The Insanity of George III,
Bull. Menniger Clin., 28: May, 1964.
GuTTMACHER, M. : Jack Ruby, the Law, and
Psychiatry, Johns Hopkins Mag., May, 1964.
HuFFER, v., Scott, W. H., Connor, T. B., and
LoviCE, H : Psychological Studies of Adult
Male Patients with Sexual Infantilism Be-
fore and After Androgen Therapy, Ann. In-
tern. Med., 255-368, 1964.
Addendum to above article appearing as
Letter to the Editor, Ann. Intern. Med.. Dec,
1964.
Book Review : Psychobiological Approaches
to Social Behavior by P. H. Leiderman and
D. Shapiro, Stanford University Press, Curr.
Med. Dig., 32: 398, 1965.
Kenny, T., Baldwin, R., and Mackie, J. B. :
Incidence of Minimal Brain Injury in
Adopted Children, Maryland J . Med. In press.
Klee, G. D., Kramer, M., Tuerk, I., Bahn,
A., and Gorwitz, K. : Psychiatric Services
Received by Residents of an Entire State
During a One Year Period. Maryland Psychi-
atric Case Register : Analysis of the First
Year's Experience, Public Health Rep. In
press.
Klee, G. D. : Psychiatry and PubHc Health.
The Pubhc Health Nurse in Psychiatric
Home Care, Dis. Nerv. Syst.. 25: 476-479,
1964.
Kramer, M., Tuerk, I., Bahn, A., Gorwitz,
K., and Klee, G. D. : Psychiatric Services
Received by Residents of an Entire State
During a One Year Period. Maryland Psychi-
atric Case Register : Analysis of the First
Year's Experience, Public Health Rep. In
press.
Kramer, M., Monroe, R. R., Goulding, R.,
and Wise, S. : EEG Activation of Patients
Receiving Phenothiazines and/or Chlordia-
zepoxide. In press.
Krantz, J. C, and Braude, M.D. : Toxicity and
Convulsive Activity of a Series of Theophyl-
line Derivatives. To.ric. Appl. Pharmacol..
7: 291-300, 1965.
KuBiE, L. : Lecture, APA Regional Meeting,
The Ontogeny of Racial Prejudice, Novem-
ber 20, 1964. In press.
Kubie, L. : American Psychoanalytic Associa-
tion, The Thinking Process, the Dream Pro-
cess and the Dream, December 6, 1964. In
press.
Kubie, L. ; Book Review: City of Night, by
John Rechy, Grove Press, New York, 1963,
/. Nerv. Ment. Dis., 139: August, 1964.
Kubie, L. : Editorial : The Changing Economics
of Psychotherapeutic Practice, /. Nerv. Ment.
Dis., 139: 311-312, 1964.
Kubie, L. : Critique : The Effects of Psycho-
therapy, by Hans J. Eysenck, Int. J. Soc.
Psychiat., 1: 175-178, 1965.
Kubie, L. : The Scientific Problems of Psycho-
analysis, Ch. 17, 316-340, Scientific Psychology
edited by Benj. B. Wolman and E. Nagel.
Basic Books, Inc., New York, 1965.
Kubie. L. ; The Biological Basis of Psychiatry :
Viewpoint of the Psychoanalyst, Ch. 17, 135-
143, Recent Advances in Biological Psy-
chiatry, Vol. VIII, edited by Jos. Wartis.
Plenum Press, New York, 1965.
Kubie, L. : Blocks to Creativity. International
Science and Technology, 69-78, June, 1965.
Kubie, L. : The Struggle Between Proconscious
Insights and Psychonoxious Rewards in Psy-
chotherapy, Emil A. Gutheil Memorial Con-
ference, October 25, 1964. In press.
Kubie, L. : Boston Conference on Training in
Psychiatry, October 30, 1964. In press.
Kubie, L. : The Future of the Private Psychi-
atric Hospital, Lowell Institute Series,
Boston, M. G. H. March, 1964. In press.
Kubie, L. : Editorial : A Tribute to Louis
Dublin, Multiple Determinants of Suicidal
Efforts, J. Nerv. Ment. Dis., 138: 3-8, 1964.
Kubie, L. : Editorial : The Teleological Fallacy
in Dynamic Psychology, /. Nerv. Ment. Dis.,
138: 103-104, 1964.
Kubie, L. : Research in : Protecting Preconsci-
ous Functions in Education ; Papers and Re-
ports from the ASDC Seventh Curriculum
Research Institute held in Washington, D. C,
on December 2, 1961. Transactions published
by the Association in April, 1964, pp. 28-42.
Kubie, L. : New Forces Constraining the
American Family ; delivered in New York
on the occasion of the 75th Anniversary of
the Child Study Association of America, at
its 39th Annual Conference, Monday, March
4, 1963. Published for the Association by
Better Homes and Gardens, and distributed
by the Association, April, 1964, pp. C1-C5.
Kubie, L. : A School of Psychological Medi-
cine Within the Framework of a Medical
School and L'niversity, reprinted from the
/. Med. Educ, 39: May, 1964.
Kubie, L. : Provisions for the Care of Children
]'ol. ^L N.
MEDICAL SCHOOL SECTION
of Divorced Parents : A New Legal Instru-
ment, Yak Lazi' J., 73: 1197-1200, 1964.
Klbie. L. : Traditionalism in Psychiatry, /.
X.-n: Mail. Dis.. 139: 6-19, 1964.
KriiiE. L. : Editorial : The Challenge of Divorce,
/. Ncn: Ment. Dis., 138: 511-512, 1964.
Lkvenson, p. K., Ferster. C. B., and Findley,
J. D. : A Method for Training Unrestrained
Primates to Receive Drug Injuctions, /.
Exl>. Anal. Bchaz:, 7, 1964.
LovicE, H., HuFFER, V., ScoTT, W. H., and
CoN'NOR, T. B. : Psychological Studies of
.Adult Male Patients with Sexual Infantilism
Before and After Androgen Therapy, .-liiii.
Intern. Med., 255-368, 1964.
.Addendum to above article appearing as Letter
to the Editor, Ann. Intern. Med., Dec, 1964.
Review : Psychobiological Approaches to
Social Behavior, by P. H. Leiderman, and D.
Shapiro. Stanford L^niversity Press, C\irr.
Med. Dig., 32: 398, 1965.
M.MKiE. J. B., Kenny, T., and Baldwin, R. :
Incidence of Minimal Brain Injury in Adopted
Children, Maryland Med. J. In press.
M.MKiE, J. B., and Beck, H. C. : Personality
Organization and Brain Damage, Psychiat.
Spectator, 1: Sept., 1964.
M.vcKiE, J. B., and Beck, H. C. : Age, Intelli-
gence and CFF, Psychomotor Skills. In press.
MicKLE, W. A., and Monroe, R. R. : Chloralose
.Activation of the EEG in Psychiatric Patients.
In press.
Monroe, R. R., and Braude, M. C. : Neuro- and
and Psychopharmacologic Studies of Alpha-
glucochloralose (AGS) and Dimethylsul-
fo.xide (IMSO), Fed. Proc. 24: 390, 1965.
Monroe, R. R., and Braude, M. C. : Dimethyl-
sulfoxide : Solubilizing and Interactive EfTects
with Alphaglucochloralose. In press.
Monroe. R. R., and Balis, G. U. : The Pharma-
cology of Chloralose : A Review, Psy-
chopharmacologia, 6: 1-30, 1964.
Monroe, R. R., and Mickle, W. A. : Chloralose
Activation of the EEG in Psychiatric
Patients. In press.
AIonroe, R. R., Goulding, R., Kramer, M.,
and Wise, S. : EEG Activation of Patients
Receiving Phenothiazines and/or Chlordia-
zepoxide. In press.
Monroe, R. R., and Dale, R. : Chlordiaze-
poxide in the Treatment of Patients with
Activated EEC's. In press.
Monroe, R. R., and \\'ise. S. : Combined Pheno-
thiazine, Chloriazepoxide and Primidone
Therapy for Uncontrolled Psychotic Patients.
In press.
M(n( HAR, J., and Bass, B. : Experiences in
Group Counseling with Aging Men in an
Out-patient Setting, Geriatrics.
Norman, J., and Euiier, M. : Repeated Use of
the Bender Gestalt Test in a Study of an
Induced Toxic State, Perceptual and Motor
Skills, 1965. In press.
Overall, B., and Aronson, H. : Treatment Ex-
pectations of Patients in Two Social Classes.
In press.
Overall, B., and -Aronson, H. : Expectations of
Psychotherapy in Patients of Lower Socio-
economic Class, reprinted in Mental Health
of the Poor, edited by Riessman, Cohen, and
Pearl, The Free Press of Glencoe, Collier-
Macmillan Ltd., London, 1964.
Pope, M., and Siegman, A. W. : An Intercor-
relational Study of Some Indices of Verbal
Fluency, Psychological Rep., 15: 303-310,
1964.
Pope, B., and Siegman, A. W. : Interviewer
Specificity and Topical Focus in Relation to
Interviewee Productivity, /. Verbal Behav.
In press.
Pope, B., and Siegman, A. W. : Efifects of
Question Specificity and Anxiety Producing
Messages on Verbal Fluency in the Initial
Interview, /. Personality Social Psychol. In
press.
Pope, B., and Siegman, A. W. : Personality
Variables Associated with Productivity and
Verbal Fluency in the Initial Interview, APA
Proceedings, 1965. In press.
Rafferty, F. : Group Organization Theory and
the Adolescent Inpatient Unit in Problems
of Vonth: Transition to Adulthood in a
Changing World, edited by Muzafer and
Caroly Sherig, Aldine Publishing Co.,
Chicago, Illinois, 1965.
Sata, L. S. : Pragmatic Psychiatry and Travel-
ing Community Health (Mental) Clinics,
Ment. Hyg., 600-604, 1964.
Sata, L. S., and Fowler, H. B. : Clinic Staff
Changes Create Community Anxiety, Ment.
Hasp., 612-617, 1964.
Schleifer, C. B., and Derbyshire, R. : De-
segregation of a State Mental Hospital for
Negroes: A Study of Staff .Attitudes, Amcr.
J. Psychiat.. 121: April, 1965.
Schleifer, C. B., and Derbyshire, R. : Symp-
/»/v. 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
toms and Sj'mptom Change in Hospitalized
Negro and White Mental Patients, with R.
Brown, /. Hum. Bchav. In press.
ScHXAPER, X. : Management of Emotional Dis-
orders : A Manual for Physicians, A. H.
Chapman, ]. Ncrv. Ment. Dis., 138: Jan., 1964.
ScHXAPER, N. : Should the Adopted Child Be
Told that He is Adopted, Maryland Med. J.,
13: 35, 1965, abstracted by Pediatric Digest,
Mod. Med.. Curr. Med. Dig., and Obstet.
Gyncc. Survey.
ScHNAPER, N. : Care of the Dying Patient,
Med. Times, May, 1965.
Schuster, C, Findley, J. D., and Zi.m.merman,
J. : Second-Order Avoidance Behavior Under
24-Hour Control Experiments, 1964. In press.
ScoTT, W. H., Connor, T. B., Lovice, H., and
HuFFER, V. : Psychological Studies of Adult
Male Patients with Sexual Infantilism Be-
fore and After Androgen Therapy, Ann.
Intern. Med., 255-368, 1964.
Addendum to above article appearing as Letter
to the Editor, Ann. Intern. Med., Dec. 1964.
Book Review: Psychobiological Approaches
to Social Behavior, P. H. Leiderman and D.
Shapiro, Stanford University Press, Curr.
Med.Dig.,Z2:i9i, 1965.
SiEGMAX, A. W., and Pope^ B.: An Intercor-
relational Study of Some Indices of Verbal
Fluency, Psychologic. Reports, 15: 303-310,
1964.
SIEGM.A.X, A. W., and Pope, B. : Interviewer
Specificity and Topical Focus in Relation to
Interviewer Productivity, /. Uerb. Bclniv. In
press.
SiEGMAX, A. W., and Pope, B. : Effects of
Question Specificity and Anxiety Producing
Messages on Verbal Fluency in the Initial
Interview, /. Personality Social Psychol. In
press.
SiEGMAX, A. \V., and Pope, B.: Personality
Variables Associated wdth Productivity and
Verbal Fluency in the Initial Interview, APA
Proceedings, 1965. In press.
Styrt, J.: Review: The Mask of Sanity, 4th
Ed., by Clockley, Bull. Hopkins Hasp. In
press.
Tuerk, L, Bahn, A., GoRwiTz, K., Rlee, G. D.,
and Kramer, J. : Psychiatric Services Re-
ceived by Residents of an Entire State During
a One Year Period. Maryland Psychiatric
Case Register : Analysis of the First Year's
Experience, Public Health Rep. In press.
Tuerk, I., and Gilbert, M. S. W. : Analysis
of an Open-Ended Group for Alcoholic
Patients.
Weintraub, W., and Aronson, H. : The Appli-
cation of Verbal Behavior Analysis to the
Study of Psychological Defense Mechanisms.
II : Speech Pattern Associated with Impulsive
Behavior, /. Ncrv. Ment. Dis., 1.39: July,
1964.
Weintraub, W., and Aronson, H. : The Appli-
cations of Verbal Behavior Analysis to the
Study of Psychological Defense Mechanisms.
Ill: Speech Pattern Associated with De-
lusional Behavior. Accepted for publication.
Weisman, M. : The Prague Sobering-up
Stations : An Eye-Witness Report, Maryland
Med. J., Oct., 1964.
Weisman, M. : Psychoanalysis and Community
Psychiatry, Science and Psychoanalysis. 8:
1965.
Will, O. : The Beginning of Psychotherapeutic
E.xperience, Modern Psychotherapeutic Prac-
tice, edited by Arthur Burton. To be pub-
lished spring, 1965.
Will, O. : Schizophrenia and the Psychothera-
peutic Field, Contemporary Psychoanalysis,
fall, 1964.
Will, O. : The Schizophrenic Patient, the
Psychotherapist, and the Consultant. To be
published in Contemporary Psychoanalysis.
Wise, S., Monroe, R. R., Goulding, R., and
Kramer, M. : EEG Activation of Patients Re-
ceiving Phenothiazines and/or Chlordiazepox-
ide. In press.
Wise, S., and Monroe, R. R. : Combined Pheno-
thiazine, Chlordiazepoxide and Primidone
Therapy for Uncontrolled Psychotic Patients.
In press.
Young, I., and Aronson, H. : Treatment Ex-
pectations of Patients in Two Social Classes,
Social Work. In press.
Zl.MMERMAN, J., ScHUSTER, C, and FiNDLEV,
J. D. : Second-Order Avoidance Behavior
Under 24-Hour Control E.xperinients, 1964.
In press.
DEPARTMENT OF RADIOLOGY
Bloedorn, F. G. : Therapy of Cancer and Allied
Diseases by Interstitial Intracavitary and Sur-
face Gamma-Ray Therapy, The Science of
Ionizing Radiation: Modes of Application,
Charles C Thomas, Springfield. Illinois, 1965.
Uol. .i/. No. '3
MEIUC.IL SCHOOL SECTIO.S
Bloedorn, F. G., and Wizexberc, M. J.: Pre-
operative Irradiation: Basis for its Indi-
cation, Radiol. Clin. (Basel), 33: 287-299,
1964.
Bloedorx. F. G., Wizenberg, M. J., Cowley,
R. A., CicciA. C. A., Mercado. J., Jr.. and
LiNBERG, E. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Anicr. J. Roc»tycn.,
92: 77-87, 1964.
Cowley, R. A., Wizenberg. M. J., Bloedorn,
F. G., CucciA, C. A., Mercado, J., Jr., and
LiXBERG, E. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Amcr. J. Rociitgcit.,
92: 77-87, 1964.
Clccia. C. a., Cowlev, R. a., \\'izexberg,
M. J., Bloedorn, F. G., Mercado, J., Jr., and
LixBERG, E. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Aiiwr. J. Roenti]C».,
92: 77-87, 1964.
Dexxis, J. M. : Excretory Urography as a
Screening Procedure for Renovascular Hyper-
tension. Maryland Med. J. .Accepted for publi-
cation, August, 1965.
LixBERG, E. J., Mercado, J., Jr., Clccia, C. A.,
Cowley, R. A., Wizenberg, J. J., and Bloe-
dorn, F. G. : Preoperative Irradiation in
Bronchogenic Carcinoma, Amer. J. Roentgen.,
92: 77-87, 1964.
Lixberg. E. J., and Wizexberg, M. J.: Further
Experiences witli Preoperative Irradiation in
Bronchogenic Carcinoma, Jour. Thorac.
Cardiov. Stirg., 1965.
Lyox'^, J. A. : Cardiac Evaluation from Routine
Chest Films, Maryland Med. J., 13: 69, 1964.
McDoucall, R. S., and Robinson, J. E. : A
Simple, Inexpensive, Manually Operated Iso-
does Plotter. Accepted for publication in
Amer. J. Roentgen.
Mercado, J., Jr., Cuccia, C. A., Cowley, R. A.,
Wizenberg, M. J., Bloedorn, F. G., and
Lixberg, E. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Amer. }. Roentgen.,
92: 77-87,1964.
Robinson, J. E. : Effects of Irradiation in Cell
Cultures, Chapter 12. The Science of Ionizing
Radiation : Modes of .4ffl'catio)i. Charles C
Thomas, Springfield, Illinois, 1965.
Robinson, J. E., and McDoug.\ll, R. S. : A
Simple, Inexpensive, Manually Operated Iso-
dose Plotter. Accepted for publication in
Amer. J. Roentgen.
-Seydel, H. G. : Hemorrhage in Ehrlich Ascites
Tumor, Nature (London), 206, 1965.
Sevdel, H. G. ; The Diameters of the Cereliral
Arteries of the Human Fetus, The Anatomical
Rev.. 150, Sept., 1964.
Seydel. H. G. : Radiation Induced Changes in
the .-Xcridine Organgc Staining of Exfoliated
Cells from Human Cancer. .Accepted for
publication in Cancer.
Seydel, H. G. : Severe Psoriasis Complicating
Radiation Therapy. Accepted for publication
in /. Mich. Med. Soc.
Wizenberg, M. J., and Bloedorn, F. G. : Pre-
operative Irradiation ; Basis for its Indi-
cation, Radiol. Clin. (Basel), 33: 287-299,
1964.
Wizenberg, M. J., Bloedorn, F. G., Cowley.
R. A., Cuccia, C. A., Mercado, J., Jr.. and
Linberg, E. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Amcr. J. Roentgen.,
92: 77-87, 1964.
Wizenberg, M. J., and Linberg, E. J. : Further
E.xperiences with Preoperative Irradiation in
Bronchogenic Carcinoma, Jour. Thorac.
Cardiov. Surg., 1965.
WoLFEL, D. A. : Lymphicovenous Communica-
tions : A Clinical Reality. Accepted for publi-
cation by Amer. J. Roentgen.
^^'oLFEL, D. A. : Aortography : A Practical Ap-
proach, Maryland Med. J., 13: 12, 1964.
RADIOISOTOPE LABORATORY
Connor, T. G., and Workii.\n, J. G. : Pre-
operative Localization of Parathyroid Adeno-
mata, /. Nucl. Med., 5: 353, 1964.
Workman, J. G., and Connor, T. G. : Pre-
operative Localization of Parathyroid Adeno-
mata, /. Nucl. Med., 5: 353, 1964.
Workman, J. G. : Localization of Parathyroid
Adenomas by Radioisotope Technics Clinical
Aspects. To be published as a part of a
Symposium on Advances in Nuclear Medicine
— Hahnemann School of Medicine, Phila-
delphia, Penn., March, 1965.
DEPARTMENT OF SURGERY
Attar, S., Beech, A., Cowley, A. R., and
Mansberger, a. R. : The Possible Relation-
ship of Certain Chromatographic Changes to
Coagulation Aberrations in Hypotensive
Patients, /. Trauma, 5: 96, 1965.
Attar, S., Henning, G., Blair, E., Michaelis,
M., Esmond, W. G., and Cowley, R. A. : The
Effect of Hyperbaric O.xygenation (OPH)
Julv. 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNirERSITV OF MARYLAND
on Three Forms of Shock — Traumatic,
Hemorrhagic, and Septic, /. Trauma, 4: 652-
663, 1964.
Attar, S., Cowley, R, A., Blair, E., Ollo-
DART, R. M., and Esmond, W. : Prevention and
Treatment of Shock by Hyperbaric Oxygena-
tion, Ann. N.y. Acad. Sci., 117: 673, 1965.
Attar, S., Ollodart, R. M., Mansberger, A. R.,
Cowley, R. A., and Buxton, R. W. : Therapy
of Refractory Shock. Accepted for pubhca-
tion, Ann. Surg.. 1965.
Attar, S., Cowley, R. A., Blair, E., and Ollo-
dart, R. M. : Hyperbaric Oxygen (OHP)
Therapy in Shock and Hypotension. In press.
Attar, S., Mansberger, A., Ollodart, R. M.,
Cowley, R., and Buxton, R. : Therapy of
Refractory Shock, Ann. Surg., June, 1965.
Attar, S., Blair, E., Ollodart, R. M., and
Cowley, R. : Hyperbaric Oxygen in Shock,
Anicr. Surg. In press.
Attar, S., Mansberger, A., Ollod.\rt, R. M.,
Cowley, R., and Buxton, R. : Therapy of
Refractory Shock. In press.
Bains, J. W., Ketcham, A. S., and Crawford,
D. T. : A Standard Model for Tensiometric
Studies, National Cancer Institute, /. Surg.
Res., 5: June, 1965.
Beech, A., Attas. S., Cowley, A. R., and
Mansberger, A. R. : The Possible Relation-
ship of Certain Chromatographic Changes to
Coagulation Aberrations in Hypotensive
Patients, /. Trauma, 5: 96, 1965.
Blair, E., Michaelis, M., Henning, G., Attar,
S., Esmond, W. G., and Cowley, R. A. : The
Effect of Hyperbaric Oxygenation (OPH)
on Three Forms of Shock — Traumatic,
Hemorrhagic and Septic, /. Trauma, 4: 652-
663, 1964.
Blair, E., Ollodart, R. M., Cowley, R., Attar,
S., and Esmond, W. : Prevention and Treat-
ment of Shock by Hyperbaric Oxygenation,
Aim. N.y. Acad. Sci., 117: 673, 1965.
Blair, E., Ollodart, R. M., Cowlev, R., and
Attar, S. : Hyperbaric Oxygen (OHP)
Therapy in Shock and Hypotension. In press.
Blair, E., Ollodart, R. M., Attar, S., and
Cowley, R. : Hyperbaric Oxygen in Shock,
Amcr. Surg. In press.
Buxton, R. W. : Peptic Ulcer : Theory and
Therapy. (Panelists: I. J. Pincus, R. W.
Buxton, and R. O. Kraft.) Univ. Mich. Med.
Bull., 30: May- June, 1964.
Buxton, R. W., Cox, E. F., and Flotte. C. T. :
Dextran in Treatment of Thrombophlebitis,
Surgery, 57: 225-229, 1965.
Buxton, R. W., Reynolds, B. D., and Leveqce,
T. F. : The Mast Cell as an Indicator of the
Extent of Trauma, Arch. Surg. (Chicago).
Also presented in the Mast Cell, edited by
Hans Selye. For release 1965.
Buxton, R. W., Cowley, R. A., Attar, S.,
Ollodart, R. M., and Mansberger, A. R. :
Therapy of Refractory Shock. Accepted for
publication, Ann. Surg., June, 1965,
Buxton, R., Cowley, R., Attar, S., Mans-
berger, A., and Ollodart, R. M. : Therapy
of Refractory Shock, Ann. Surg., June, 1965.
Buxton, R., Cowley, R., Attar, S., Mans-
berger, A., and Ollodart, R. M. : Therapy
of Refractory Shock. In press.
Cowley, A. R., Beech, A., Attar, S., and
Mansberger, A. R. : The Possible Relation-
ship of Certain Chromatographic Changes
to Coagulation Aberrations in Hypotensive
Patients, /. Trauma, 5: 96, 1965.
Cowley, R. A., Esmond, W. G., Attar, S.,
Henning, G., Blair, S., and Michaelis, M. ;
The Effect of Hyperbaric Oxygenation
(OPH) on Three Forms of Shock — Trau-
matic, Hemorrhage, and Septic, /. Trauma,
4: 652-663, 1964.
Cowley, R. A., Blair, E., Ollodart, R. M.,
Attar, S., and Esmond, VV. : Prevention and
Treatment of Shock by Hyperbaric Oxygena-
tion, Ann. N.Y. Acad. Sci., 117: 673, 1965.
Cowley, R. A., Attar, S., Ollodart, R. M.,
Mansberger, A. R., and Buxton, R. W. :
Therapy of Refractory Shock, Ann. Surg.,
June, 1965. Accepted for publication.
Cowley, R. A., Blair, E., Ollodart, R. M.,
and Attar, S. : Hyperbaric O.xygen (OHP)
Therapy in Shock and Hypotension. In press.
Cowley, R., Attar, S., Mansberger, A., Ollo-
dart, R. M., and Buxton, R. : Therapy of
Refractory Shock, Ann. Surg., June, 1965.
Cowley, R., Attar, S., Blair, E. and Ollo-
dart, R. M. : Hyperbaric Oxygen in Shock,
Am. J. Surg. In press.
Cowley, R., Attar, S., Mansberger, A., Ollo-
dart, R. M., and Buxton, R. : Therapy of
Refractory Shock. In press.
Cox, E. F. : Safer Method of Translumber
Aortography, Hemobilia Secondary to Vim-
Silverman Needle Biopsy, The Occluded Ex-
tremity — .\ Shock Preparation, and Washout
Vol. .>!. No. 3
MF.liIC.IL SCHOOL Sl-CTIOX
Acklosis Following Aortic Resection. In
preparation.
Cox, E. F., Flotte, C. T., and Blxto.v. R. \V. :
Dcxtran in Treatment of Thronibophlobitis,
Siirtirry. 57: 225-229, 1965.
Co.x, E. F. : Patient Evaluation for Pelvic Ex-
enteration, Amer. Surg., 30: 574, 1964.
Cox, E. F. : Film presentation, Hcmimaxil-
Icctoiiiy for Adenocarcinoma , on closed circuit
T. V. at the Annual Meeting of tlic .•\nierican
Dental Association, San Francisco. Xov. 10,
1964, with McDonald K. Hamilton, D.D.S.,
and Richard P. Beimler, D.D.S.)
Cox, E. F. : Exhibit, Safer Method of Tnins-
lumbcr Aortography, Southeastern Surgical
Congress, Washington, D. C, Mar. 29-April
1. 1965.
Crawford. D. T. : Serum Lactate Dehydrogenase
in the Immediate Postoperative Period,
Amer. Surg., 30: Oct., 1964.
Cr.\\vford, D. T., Baixs, J. W., and Ketcham,
A. S. : A Standard Model for Tensiometric
Studies, National Cancer Institute, /. Surg.
Res., 5: June, 1965.
Esmond, W. G., Attar, S., Henning. G., Blair,
E., MicHAELis, M., and Cowley. R. A.:
The Eflfect of Hyperbaric Oxygenation
(OPH) on Three Forms of Shock— Trau-
matic. Hemorrhagic, and Septic. /. Trauma,
i: 652-663, 1964.
Esmond, W., Attar, S., Cowley, R. A., Blair,
E., and Ollodart, R. M. : Prevention and
Treatment of Shock by Hyperbaric Oxygena-
tion, Anil. N.Y. Acad. Sci., 117: 673, 1965.
Flotte, C. T., Buxton, R. W., and Cox, E. F. :
Dextran in Treatment of Thrombophlebitis,
Surgery, 57: 225-229, 1965.
Flotte, C. T. : Dextran in Treatment of
Thrombophlebitis, Maryland Med. J., 13:
76-77, 1964.
Flotte, C. T. : Use of Hydrogen Peroxide as
a Source of Oxygenation in the Perfusion of
Isolated Organs, Surg. Forum, 15: 275-277,
1964.
Flotte. C. T. ; Reconstituted Collagen Sutures :
Experimental Evaluation, Arch. Surg.
(Chicago), 90: 86-89, 1965.
Henning, G., Blair, E., Michaelis, M., Attar,
S., Esmond, W. G., and Cowley, R. A. : The
Effect of Hyperbaric Oxygenation (OPH)
on Three Forms of Shock — Traumatic,
Hemorrhagic, and Septic, /. Trauma, 4: 652-
663. 1964.
Jklenko, C, III: Marfanil Mystery, Surg.
Oyncc. Ohstct. In press.
Just-Vxera. J. O., and Yeager, G. H. : Clinical
Use of Rapidly Polymerizing Tissue Ad-
hesive : Preliminary Report, Amer. Surg.,
30: March, 1964.
Just-Viera, J. O., and Yeager, G. H. : Massive
Pulmonary Embolism: II Predictable Mor-
tality and Cardiopulmonary Changes in Dogs
Breathing Room .Air, .Inn. Surg., 1.59: April,
1964.
Just-Viera, J. O., and Yeager, G. H. : Massive
Pulmonary Embolism : IV The \'alue of
Hyperbaric O-xygen as Therapy, /. Thorac.
Cardiov. Surg., 48: 185-199, 1964.
Ketcham, A. S., Crawford, D. T., and Bains,
J. W. : A Standard Model for Tensiometric
Studies, National Cancer Institute, /. Surg.
Res., 5: June, 1965.
Leveque. T. F., Reynolds, B. D., and Buxton,
R. W. : The Mast Cell as an Indicator of
the Extent of Trauma, Arch. Surg. (Chicago).
Also presented in the Mast Call, edited by
Hans Selye. For release 1965.
Lix-BERG, E., and Mansberger, A. R. : First
Rib Resection for Distal Exposure of Sub-
clavian Vessels, Surg. Gynec. Obstct., 120:
579, March, 1965.
AIansberger, a. R. : Therapy of Refractor
Shock, Maryland Med. /., 13: 78, 1964.
Mansberger, A. R. : The Diagnostic Value of
Abdominal Paracentesis with Special Refer-
ences to Peritoneal Fluid Ammonia Levels,
Amer. Castroent., 42: 150, 1964.
Mansberger, A. R. : The Possible Relationship
of Certain Chromatographic Changes to
Coagulation Aberrations in Hypotensive
Patients with S. Attar, A. Beech, and A. R.
Cowdey, /. Trauma, 5: 96, 1965.
Mansberger, A. R. : First Rib Resection for
Distal Exposure of Subclavian Vessels with
E. Linberg, Surg. Gynec. Obstct., 120: 579,
1965.
Mansberger, A. R., Ollodart, R. M., Attar,
S., Cowley, R. A., and Buxton, R. W. :
Therapy of Refractory Shock. Accepted for
publication, Ann. Surg., June, 1965.
Mansberger, A. R., and Young, J. D. : Am-
mona Levels as an Aid to the Diagnosis of
Urinary Extravasation. Accepted for publi-
cation, /. Urol.
Mansberger, A. R., Ollodart, R. M., Attar,
Julx. 1966
BULLETIS OF THE SCHOOL OF MEDICINE. VKIVERSITY OF MARYLAND
S., CowLEV, R., and Buxton, R. : Therapy
of Refractory Shock, Ann. Surg., June, 1965.
Mansberger, a. R., Ollodart, R. M., Attar,
S., Cowley, R., and Buxton, R. : Therapy
of Refractory Shock. In press.
Mtchaelis, M., Blair, E., Henning, G., At-
tar, S., Esmond, W. G., and Cowley, R. A. :
The Effect of Hyperbaric Oxygenation
(OPH) on Three Forms of Shock — Trau-
matic, Hemorrhagic, and Septic, /. Trauma,
4: 652-663, 1964.
Ollodart, R. M., Blair, E., Cowley, R.,
.'\ttar, S., and Esmond, W. : Prevention and
Treatment of Shock by Hyperbaric Oxygena-
tion, Ann. N.y. Acad. ScL, 117: 673, 1965.
Ollodart, R. M. : High Pressure Oxygen as
an Adjunct in Experimental Bacteremic
Shock, J.A.M.A., 191: 736, 1965.
Ollodart, R. M., Mansberger, A. R., Attar,
S., Cowley, R. A., and Buxton, R. W. :
Therapy of Refractory Shock. Accepted for
pubHcation, Ann. Surg., June, 1965.
Ollodart, R. AI.. Blair, E., Cowley, R.,
and Attar, S. : Hyperbaric Oxygen (OHP)
Therapy in Shock and Hypotension. In press.
Ollodart, R. M. : OHP as an Adjunct in
Septic Shock, Symposium on Shock, National
Research Council. In press.
Ollod.\rt, R. M. : Bacterial Defense in Shock,
Aincr. Surg. In press.
Ollodart, R. M., Mansberger, A., Attar, S.,
Cowley, R., and Buxton, R. : Therapy of
Refractory Shock, Ann. Surg., June, 1965.
Ollodart, R. M., Blair, E., Attar. S., and
Cowley, R. : Hyperbaric Oxygen in Shock,
Amcr. Surg. In press.
Ollodart, R. M., Mansberger, A., Attar, S.,
Cowley, R., and Buxton, R. : Therapy of
Refractory Shock. In press.
Reynolds, B. D., Buxton, R. W., and Leve-
que, T. F. : The Mast Cell as an Indicator
of the Extent of Trauma, Arch. Surg. Also
presented in the Mast Cell, edited by Hans
Selye. For release 1965.
Shipley, E. R. : Re-Evaluation of Furacin as
a Local Agent in the Treatment of Surface
Infections, Amcr. Surg., 31: April, 1965.
Yeager, G. H., and Just-Viera, J. O. : Clinical
Use of Rapidly Polymerizing Tissue Ad-
hesive; Preliminary Report, Amcr. Surg., 30:
March, 1964.
Yeager, G. H., and Just-Viera, J. O. : Massive
Pulmonarv Embolism : II Predictable Mor-
tality and Cardiopulmonary Changes in Dogs
Breathing Room Air, Ann. Surg., 159: April,
1964.
Yeager, G. H., and Just-Viera, J. O. : Massive
Pulmonary Embolism : IV The Value of
Hyperbaric Oxygen as Therapy, /. Tlior.
Cardioz: Surg., 48: 185-199, 1964.
Young, J. D., and Mansberger, A. R. : Am-
monia Levels as an Aid to the Diagnosis
of Urinary Extravasation. Accepted for
publication, /. Urol.
Division of Neurological Surgery
Adams, J. E., Meyer, P. D., and Henderson.
C. M. : Development of a New Carotid
Artery Aneurysm in a Patient with a Previ-
ously Operated Ipsilateral Carotid Aneurysm.
Arnold, J. G., Jr. : Neurosurgical Experience
with Echoencephalography, Med. Ann. D. C,
June, 1964.
Arnold, J. G., Jr., Wagner, J. A., and AIever.
P. D. : Spontaneous Posterior Fossa Subdural
Hematoma — an Unusual Complication of
Hodgkin's Disease, Bull. Sch. Med. Uniz:
Maryland, April, 1965.
DuRKAN, J. P., and Russo, G. L. : Ultrasonic
Fetal Cephalometry ; Accuracy, Limitations
and Applications. Submitted for publication.
Henderson, C. M., Meyer, P. D., and Adams.
J. E. : Development of a New Carotid Artery
Aneurysm in a Patient with a Previously
Operated Ipsilateral Carotid Aneurysm.
Meyer, P. D., Henderson, C. M., and Adams.
J. E. : Development of a New Carotid Artery
Aneurysm in a Patient with a Previously
Operated Ipsilateral Carotid Aneurysm.
Meyer, P. D., Wagner, J. A., and Arnold,
J. G. : Spontaneous Posterior Fossa Subdural
Hematoma — an Unusual Complication of
Hodgkin's Disease, Bull. Sch. Med. Univ.
Maryland, April, 1965.
MosBERG, W. H., Jr. : Graduate Medical Edu-
cation in the United States of America with
Some Special Reference to Neurological
Surgery. To be published in Indian J. Med.
Educ.
Mosberg, W. H., Jr. : Report of National Ad
Hoc Head Injury Nomenclature Committee,
Clin. Neurosurg., Vol. 13.
Russo, G. L. : Neurosurgical Experience with
Echoencephalography, Med. Ann. D. C,
June, 1964.
Russo, G. L. : Ultrasonic Fetal Cephalometry :
To/. 51, No 3
MEDICAL SCHOOL SECTIOX
Accuracy. Limitations and Apiilications, with
James r. Diirkan. Submitted lor publication.
\\".\r,NKi(. J. A., Meyek, p. D., and Arnold,
J. G. : Spontaneous Posterior Fossa Subdural
Hematoma — an Unusual Complication of
Hodgkin's Disease, Bull. Sell. Med. Univ.
M.iryUmd, April, 1965.
Division of Otolaryngology
Bl.\.\cii.\rd, C. L., and E.ngnoth, M. L. :
Fray's Syndrome. In press.
Bi..\xcHARD, D. L., and Urban, G. E. : Hyper-
baric Oxygenation Effect on Auditory Evoked
Cortical Responses. In press.
E.vGNOTH, M. L., and Blanchard, C. L. : Frey's
Syndrome. In press.
Urb.an, G. E., and Blanchard, D. L. : Hyper-
baric O.xygenation Effect on Auditory
Evoked Cortical Responses. In press.
Division of Thoracic Surgery
Attar. S., Blair. E., Cowlev, R. A., Gutier-
REG, G. E., and Es.mond, W. G. : Hyperbaric
Oxygenation in Massive Pulmonary Embol-
ism, Dis. Chest, 46: 537, 1964.
Attar, S., Esmond, W. G., Blair, E., and
Cowlev, R. A. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Surg. Forum,
15: 200, 1964.
Attar, S., Blair, E., Cowlev, R. A., and
FiscHLER, M. : Square- Wave 250 Cycle
Cardiac Defibrillation — Use in Cardiac
Surgery, Arch. Surg., 90: 29, 1965.
Attar, S., Cowley, R. A., Bl.\ir, E., Esmond,
W. G., MiCHAELis, M., and Ollodart, R. :
Prevention and Treatment of Shock by
Hyperbaric Oxj'genation, Ann. N.Y. Acad.
Sci., 117: 673, 1965.
Attar. S., Blair, E., Henning, G., Esmond,
W. G., Cowley, R. A., and Michaelis, M. :
The Effect of Hyperbaric Oxygenation
(OHP) on Three Forms of Shock — Trau-
matic, Hemorrhagic and Septic, /. Trauma,
4:652, 1964.
Att.\r, S., Blair, E., and Esmond, W. G. :
The Effect of Hypothermia on Lung Function,
Ann. Surg., 100: 814, 1964.
Attar, S., Cowley, R. A., Blair, E., and
Esmond, W. G. : Hyperbaric Oxygen in
Shock ill Shock-Hypotension, Grune and
Stratton, 1965.
Att.\r, S., Blair, E., Esmond, W. G., and
Cowlev. R. .\. : The Vtilizalion oj Hyper-
baric O.rygenalion in Hemorrhagic Shock.
In Clinical Application oj Hyperbaric O.ry-
genalion, Elsevier Publication Co., .Amster-
dam, 1964.
Attar, S., and Cowley, R. A.: Re-evaluation
of Hyperbaric Oxygenation in Hemorrhagic
Shock, Surg. Forum, 16: 1965. In press.
.\ttar, S., Singleton, R., Hankins, J., Lin-
berg, E., Lyon, J., and Cowley, R. A.:
Congenital Anomalies of the Pulmonary
Arteries, /. Thorac. Cardiov. Ssurg. In press.
Attar, S. : Hankins, J., and Cowlev, R. A. :
Emergency Repair of Antriogenic Mitral In-
sufficiency, /. Thorac. Cardiov. Surg. In press.
Attar, S., Blair, E., Ollodart, R., and
Cowley, R. A. : Hyperbaric Oxygenation in
the Treatment of Experimental Shock, Amer.
J. Surg. In press.
Attar, S., Blair, E., Ollodart, R., and
Cowley, R. A. : Hyperbaric Oxygenation in
the Treatment of Experimental Shock, Amer.
J. Surg. In press.
Attar, S., Mansberger, A. R., Beech, A.,
and Covv'LEY, R. A. : The Possible Relationship
of Certain Chromatographic Changes to
Coagulation Aberrations in Hypotensive
Patients, /. Trauma, 5: 90, 1965.
Attar, S., Blair, E., Ollodart, R., Esmond,
W. G., and Cowley, R. A.; The Effect of
Hyperbaric Oxygenation on Bacteremia
Shock, Circulation, 29: 135-139, 1964.
Attar, S., Esmond, W. G., Blair, E., and
Cowley, R. A. : Experimental Aspects of the
Use of Hyperbaric Oxygen in Hemorrhagic
Shock, Amer. Surg., 30: 243, 1964.
Attar, S., Mansberger, A. R., Blair, E.,
Cowley, R. A., and Buxton, R. : The Therapy
of Refractory Shock, Ann. Surg. In press.
Attar, S., Mansberger, A. R., Ollodart, R.,
McLaughlin, J., and Cowley, R. A. : A
Physiologic Approach to the Correction of
Hypotension, Ann. Surg. In press.
Attar, S., Mansberger, A. R., Kirby, W. H.,
Masaitis, C, and Cowley, R. A. : The Effect
of Hemorrhagic Shock on Clotting Time in
Humans, Ann. Surg. In press.
Attar, S., Mansberger, A. R., Irani, B.,
Masaitis, C, Kirby, W. H., and Cow-ley,
R. A. : II, The Behavior of Fibrogen in
Clinical Septic Shock. In press.
Att.\r, S., Kirby, W. G., Irani, B., Masaitis,
C. A., Mansberger, A. R., and Cowley,
Jtilv, 1966
BULLETIX OF THE SCHOOL OF MEDICIXE. CXWERSITY OF MARYLAND
R. A.: Ill, The Effect of Septic Shock
in Clotting Time in Humans, Ann. Sura. In
press.
Baker. B.. Hurdle, E., Kaestxer, R., C.\rski,
T., Fraxzone, J., Lewitinn, A., Cowley,
R. A., and Esmond, W. G. : ReliabiHty
Engineering for Open Heart Surgery. BnH.
Sch. Med. Univ. Maryland. Oct., 1964.
Beech, A., Mansberger, A. R., Attar, S., and
Cowley, R. A. : The Possible Relationship
of Certain Chromatographic Changes to
Coagulation Aberrations in Hypotensive
Patients, /. Trauma, 5: 90, 1965.
Blair, E., Herman, R., and Cowley, R. A. :
Interventricular Septal Defect in Identical
Twins, /. Thorac. Cardiov Surg. In press.
Blair, E., Cowley, R. A., and Tait, M. K. :
Lactacidemia from Septic Shock in Man,
Amcr. Surg. In press.
Blair, E., Ollodart, R., Attar, S., and
Cowley, R. A. : Hyperbaric Oxygenation in
the Treatment of Experimental Shock, Anicr.
J . Surg. In press.
Blair, E., Cowley, R. A., and Buxton, R. :
Hyperbaric Oxygenation in the Treatment of
Experimental Shock, Ann. Surg. In press.
Blair. E., Cowley, R. A., Mansberger, A. R.,
and BuxTOX, R. : The Therapy of Re-
fractory Shock, Ann. Surg. In press.
Blair, E., Mansberger, A. R., Attak, S.,
Cowley, R. A., and Buxton, R. : The
Therapy of Refractory Shock, Ann. Surg. In
press.
Blair, E., Esmond, W. G., Attar, S., and
Cowley, R. A. : Experimental Aspects of the
Use of Hyperbaric Oxygen in Hemorrhagic
Shock, An,. Surg., 30: 243, 1964.
Blair. E., Hexxixg, G., Hornick, R., and
Cowley, R. A. : Hypothermia in Bacteremic
Shock, Arch. Surg., 89: 619-629, 1964.
Blair. E., Xvgren, E., and Cowley, R. A. :
A Spiral Wire Technique for Producing
Gradually Occlusive Coronary Thrombosis,
/. Thorac. Cardiov. Surg., 48: 476-485, 1964.
Blair, E., and Ollodart, R. : High Pressure
Oxygen as an Adjunct in Experimental
Bacteremic Shock, J.A.M.A., 191: 736-739,
1965.
Blair, E., Cowley, R. A., Gutierreg, and
Esmond, W. G. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Dis. Chest,
46: 537,1964.
Bl.air. E. : Clinical Hy/'othennia, McGraw-
Hill, New York, 1964.
Blair, E. : Chapter on Physiologic Effects of
Hypothermia for Textbook on Veterinary
Anesthesia, Williams and Wilkins Co., Balti-
more.
Blair, E. : Chapter on Hypothermia in Lewis'
Practice of Surgery.
Blair, E., Attar, S., Ollodart, R., and
Cowley, R. A. : Hyperbaric Oxygenation in
the Treatment of Experimental Shock, Amcr.
J. Surg. In press.
Blair, E., Ollodart, R., Cowley, R. A. and
Henning, G. : Hypoxia Resulting from Coli-
form Infections in Animals, Natl. Acad.
Sci. In press.
Blair, E., .\tt.\r, S., Cowley, R. A., Gutier-
reg, G. E., and Esmond, W. G. : Hyperbaric
Oxygenation in Massive Pulmonary Embolism,
Dis. Chest. 46: 537, 1964.
Bl.\ir, E., Esmond, W. G., Attar, S., and
Cowley, R. A. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Surg. Forum,
15: 200, 1964.
Bl.\ir, E., Attar, S., Cowley, R. A., and
FiscHLER, M.: Square-Wave 250 Cycle
Cardiac Defibrillation — Use in Cardiac
Surgery, Arch. Surg., 90: 29, 1965.
Blair, E., Cowley, R. A., Attar, S., Esmond.
W. G., MicHAELis, M., and Ollodart. R. :
Prevention and Treatment of Shock by Hyper-
baric Oxygenation, Ann. AM'. Acad. Sci..
117: 673, 1965.
Blair, E., Att.\r. S., Henning, G., Esmond.
W. G., Cowley, R. A., and Michaelis, M. :
The Effect of Hyperbaric Oxygenation
(OHP) on Three Forms of Shock — Trau-
matic, Hemorrhagic and Septic, /. Trauma.
4: 652, 1964.
Blair, E., Attar, S., and Esmond, W. G. :
The Effect of Hypothermia on Lung Function,
Ann. Surg., 100: 814, 1964.
Blair, E., Cowley, R. A., Att.\r. S., and
Esmond, W. G. : Hyfcrbaric O.rygcn in
Shock in Shock-Hy('olension, Grune and
Stratton, 1965.
Blair, E., Attar, S., Esmond, W. G., and
Cowley, R. A. : The Utilization of Hyper-
baric Oxygenation in Hemorrhagic Shock,
in Clinical Application of Hyperbaric O.ry-
genation, Elsevier Publication Co., Amster-
dam, 1964.
Blair, E., .Att.vr. S., Oli.od.\rt. R., Esmond,
To/. 5L Ni
MEDICAL SCHOOL SECTIOX
\V. G., and Cowlev, R. A.: Tlic Effect of
Hyperbaric Oxygenation on Bacteremic
Shock, Circulation. 29: 135-139, 1964.
Bloedorx, F. G., Li.nberg, E. J., Cowley, R. A.,
CucciA, C. A., Mercado, R., and Wizenberg.
M. J. : Preoperative Irradiation in Broncho-
genic Carcinoma, Amcr. J. Rocnigoi.. 92:
77, 1964.
Bloeuorx, F. G., Cowley, R. .\., Linberg, E. J.,
and Wizenberg. M. J. : Bronchogenic Carci-
noma Further Experience with Preoperative
Irradiation, /. Thorac. Cardiot: Surg. In
press.
Bi'.XTo.v. R.. Cowley. R. .A., Blair, E., Mans-
berger, A. R., and .\tt.\r, S. : The Therapy
of Refractory Shock, Ann. Surg. In press.
Blxtox, R., Blair, E., and Crowley, R. A.:
Hyi)erbaric Oxygenation in the Treatment of
Experimental Shock, Ann. Surg. In press.
Carski. T.. Fraxzoxe, J., Lewitixx, A.,
Cowley, R. A., Esmond, W. G., Kaestxer.
R.. HcRDLE, E., and Baker. B. : Reliability
Engineering for Open Heart Surgery, Bull.
Sch. Med. Uniz: Maryland, Oct., 1964.
Cowley, R. A., Esmoxd, W. G., Hexxixg, G.,
Blair, E., Attar, S., and Michaelis, M. :
The Effect of Hyperbaric O.xygenation
(OHP) on Three Forms of Shock — Trau-
matic, Hemorrhagic and Septic, /. Trainua,
4: 652, 1964.
Cowley, R. A., Attar, S., Blair, E., and
Esmond. W. G. : Hyperbaric O.rygcn in
Shock in Shock-Hyj^otcnsion. Grune and
Stratton, 1965.
Cowley, R. A.. Esmoxd. W. G., Bl.\ir, E., and
Attar, S. : The Utilization of Hyperbaric
Oxygenation in Hemorrhagic Shock, in
Clinical Application of Hyperbaric 0.rygcna-
tion, Elsevier Publ. Co., Amsterdam, 1964.
CowLEY% R. A., Beech, A., Maxsberger, A. R.,
and Attar, S. : The Possible Relationship of
Certain Chromatographic Changes to Coagu-
lation Aberrations in Hypotensive Patients,
.1. Trauma . 5: 90, 1965.
Cowley, R. A., Esmond, W. G., Ollodart, R.,
Blair. E., and Attar, S. : The Effect of
Hyperbaric Oxygenation on Bacteremic
Shock, Circulation, 29: 135-139, 1964.
Cowley, R. A., Blair, E., Esmoxd, W. G., and
Attar, S. : Experimental Aspects of the
Use of Hyperbaric Oxygen in Hemorrhagic
Shock, Amer. Surg., 30: 243, 1964.
Cowley, R. A., Blair, E., Esmoxd. W. G., and
.\ttar, S. : The Effect of Hypothermia on
Lung Function, .Inn. Surg., 160: 814-823,
1964.
Cowley, R. .A., Horxick, R., Hexxixg, G., and
Blair, E. : Hypothermia in Bacteremic
Shock, Arch. Surg., 89: 619-629, 1964.
Cowley, R. A., Nygren, E., and Blair, E. : A
Spiral Wire Technique for Producing Gradu-
ally Occlusive Coronary Thrombosis, /.
Thorac. Cardial: Surg., 48: 476-485, 1964.
Cowley, R. A., Blair, E., Gutierreg, and
Esmond, W. G. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Dis. Chest,
46:537, 1964.
Cowley, R. A., Es.moxd, W. G., Lewitixx. A.,
Franzone, J., Carski, T., Kaestxer, R.,
Hurdle, E., and Baker, B. : Reliability
Engineering for Open Heart Surgery, Bull.
Sch. Med. Univ. Maryland, Oct., 1964.
Cowley, R. A., Blair, E., Maxsberger, A. R.,
Attar, S., and Buxton, R. : The Therapy of
Refractory Shock, Ann. Surg. In press.
Cowley, R. A., McLaughlin, J., Ollodart, R.,
Maxsberger, A. R., and Attar, S. : A Physio-
logic Approach to the Correction of Hypo-
tension, Ann. Surg. In press.
Cowley, R. A., Masaitis, C, Kirby, W. H.,
Maxsberger, A. R., and Attar, S. : The
Effect of Hemorrhagic Shock on Clotting
Time in Humans, Ann. Surg. In press.
Cowley, R. A., Kirby, W. H., Masaitis, C,
Iraxi, B., Maxsberger, A. R., and Attar, S. :
II, The Behavior of Fibrogen in Clinical
Septic Shock. In press.
Cowley, R. A., Maxsberger, A. R., Masaitis,
C. A., Irani, B., Kirby, W. G., and Attar,
S. : III, The Effect of Septic Shock in Clotting
Time in Humans, Ann. Surg. In press.
Cowley, R. A., and Attar, S. : Re-evaluation
of Hyperbaric Oxygenation in Hemorrhagic
Shock, Surg. Forum, 16: 1965. In press.
CowLEY', R. A., Haxkixs, J., and Attar, S. :
Emergency Repair of Antriogenic Mitral In-
sufficiency, /. Thorac. Cardiov. Surg. In press.
Cowley, R. A., Ollodart, R., Blair, E., and
Attar, S. : Hyperbaric Oxygenation in the
Treatment of Experimental Shock, Amer. J.
Surg. In press.
Cowley, R. A., Ollodart, R., Blair, E., and
Hexxixg., G. : Hypoxia Resulting from Coli-
form Infections in .Animals, Natl. Acad. Sci.
In press.
Cowley, R. A., Herman-, R., and Blair. E. :
July, 1966
WLLETIN OF THE SCHOOL OF MEDICINE. UXU'ERSITV OF MARYLAND
Interventricular Septal Defect in Identical
Twins, /. Thorac Cardiov. Surg. In press.
CowLEV, R. A., Blair, E., and Tait, M. K. :
Lactacidemia from Septic Shock in Man,
Amcr. Surg. In press.
Cowley, R. A., Blair, E., and Buxtox, R. :
Hyperbaric Oxygenation in the Treatment of
Experimental Shock, Ann. Surg. In press.
Cowley, R. A., Bloedorn, F. G., Linberg,
E. J., Cuccia, C. A., Mercado, R., and
Wizenberg, M. J. : Preoperative Irradiation
in Bronchogenic Carcinoma, Amcr. J.
Roentgen., 92: 77, 1964.
Cowley, R. A., Lanzi, J., McLaughlik, J.,
and LiNBERG, E. J. : Traumatic Intercostal
Arteriovenous Fistula: Case Report, Ann.
Surg., 161: 218, 1965.
Cowley, R. A., Linberg, E. J., Bloedorn. F.,
and Wizenberg, M. J. : Bronchogenic Carci-
noma Further Experience with Preoperative
Irradiation, /. Tlwrac. Cardiov. Surg. In
press.
Cowley, R. A., Lyons, J., Hankins, J.,
Singleton, R., and Linberg, E. J. : Congeni-
tal Anomalies of the Pulmonary Arteries,
/. Thorac. Cardiov. Surg. In press.
Cowley, R. A., Blair, E., Attar, S., Gutier-
reg, G. E., and Esmond, W. G. : Hyperbaric
Oxygenation in Massive Pulmonary Embol-
ism, Dis. Chest, 46: 537, 1964.
Cowley, R. A., Blair, E., Esmond, W. G., and
Attar, S. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Surg. Forum.
15: 200, 1964.
Cowley, R. A., Blair, E.. Attar, S., and
Fischler, M. : Square-Wave 250 Cycle
Cardiac Defibrillation — Use in Cardiac
Surgery, Arch. Stirg., 90: 29, 1965.
Cowley, R. A., Attar, S., Blair. E., Esmond,
W. G., MiCHAELis, M., and Ollodart. R. :
Prevention and Treatment of Shock by Hyper-
baric Oxygenation, Ann. N^.Y. Acad. Sci..
117: 673, 1965.
Cuccia, C. A., Cowley, R. A., Bloedorn, F. G..
Linberg, E. J., Mercado, R., and Wizenberg,
M. J. : Preoperative Irradiation in Broncho-
genic Carcinoma, Amcr. J. Roentgen., 92:
77, 1964.
Esmond, W. G., Attar, S., Blair, E., and
Cowley, R. A. : Experimental Aspects of the
Use of Hyperbaric Oxygen in Hemorrhagic
Shock, Amer. Surg., 30: 243, 1964.
Esmond, W. G., Cowley, R. A., Lewitinn, A.,
Franzone. J., Carski, T., Kaestner, R.,
Hurdle, E., and Baker, B. : Reliability
Engineering for Open Heart Surgery, Bull.
Sch. Med. Univ. Maryland, Oct., 1964.
Esmond, W. G., Gutierreg, G. E., Cowley,
R. A., Blair, E., and Attar. S. : Hyperbaric
O.xygenation in Massive Pulmonary Embol-
ism, Dis. Chest, 46: 537, 1964.
Esmond, W. G., Attar, S., Blair, E., and
Cowley, R. A. : Hyperbaric Oxygenation in
Massive Pulmonary Embolism, Surg. Forum,
15: 200, 1964.
Esmond, W. G., Blair, E., Cowley, R. A.,
Attar, S., Michaelis, M., and Ollodart, R. :
Prevention and Treatment of Shock by Hyper-
baric Oxygenation, Ann. N.Y. Acad. Sci.,
117: 673, 1965.
Esmond, W. G., Henning, G., Blair, E., Attar,
S., Cowley, R. A., and Michaelis, M. : The
Effect of Hyperbaric Oxygenation (OHP)
on Three Forms of Shock — Traumatic,
Hemorrhagic and Septic, /. Trauma, 4:
652, 1964.
Esmond, W. G., Blair. E., and -Attar. S. : The
Eflfect of Hypothermia on Lung Function,
Ann. Surg.. 100: 814, 1964.
Esmond, W. G., Blair, E., Cowley, R. A.,
and Attar, S. : Hyperbaric Oxygen in Shock
in Shock-Hypotension, Grune and Stratton,
1965.
Esmond, W. G., Blair. E., Attar, S., and
Cowley, R. A. : The L^tilization of Hyper-
baric Oxygenation in Hemorrhagic Shock, in
Clinical Application of Hyperbaric Oxygena-
tion, Elsevier Publication Co., Amsterdam,
1964.
Esmond, W. G., Ollodart, R., Blair, E., Att.\r,
S., and Cowley, R. A. : The Effect of Hyper-
baric Oxygenation in Bacteremic Shock,
Circulation, 29: 135-139. 1964.
Fischler. M., Cowley, R. A., Blair, E., and
Attar. S. : Square- Wave 250 Cycle Cardiac
Defibrillation — L^se in Cardiac Surgery, Arch.
Surg.. 90: 29, 1965.
Franzone, J., Lewitinn, A., Cowley, R. A.,
Esmond, W. G., Carski, T., Kaestner, R.,
Hurdle. E., and Baker, B. : Reliability Engi-
neering for Open Heart Surgery, Bull. Sch.
Med. Univ. Maryland, Oct., 1964.
Gutierreg. G. E., Co\vlev, R. A., Blair, E.,
Attar, S., and Esmond. W. G. : Hyperbaric
O.xygenation in Massive Pulmonary Embol-
ism, Dis. Chest. 46: 537, 1964.
I'ol. 51, No. 3
MEDICAL SCHOOL SECTIOX
IIaxkins. J., Singleton. R., Linberg, E. J.,
Lyons, J., and Cowley, R. A. : Congenital
Anomalies of the Pulmonary Arteries, /.
Thorac. Cardial'. Surg. In press.
H.\XKINS, J., and Linberg, E. J. : Tracheo-
bronchial Obstruction Caused by an .•\berrant
Left Pulmonary Artery. In preparation.
H.^NKiNS. J., Att.-kr, S., and Cowley, R. A. :
Emergency Repair of Antriogenic Mitral In-
sufficiency, /. Tlwrac. Cardiov. Surg. In press.
Henning, G., Blair, E., Attar, S., Esmond,
W. G., Cowlev, R. a., and Michaelis, M. :
The Effect of Hyperbaric Oxygenation
(OHP) on Three Forms of Shock — Trau-
matic, Hemorrhagic and Septic, J. Trauma,
4:652, 1964.
Hex.xixg, G., Cowley, R. A., Ollodart. R.,
and Blair, E. : Hypo.xia Resulting from
Coliform Infections in Animals, Xall. Acad.
Sci. In press.
Hex^xing, G., Blair. E., Horxick. R., and
Cowley. R. A.: Hypothermia in Bacteremic
Shock, Arch. Surg., 89: 619-629, 1964.
Her.max, R., Blair, E., and Cowley, R. A. :
Interventicular Septal Defect in Identical
Twins, /. Thorac. Cardiov. Surg. In press.
Horxick, R.. Hexxing, G., Blair, E., and
Cowley, R. A. : Hypothermia in Bacteremic
Sliock, Arch. Surg., 89: 619-629, 1964.
Hurdle, E., Kaestner, R., C.\rski, T., Fran-
zoxe, J., Lewitixx, a., Cowley, R. A.,
Esmond, W. G., and Baker, B. : Reliability
Engineering for Open Heart Surgery, Bull.
Sch. Med. Univ. Maryland, Oct., 1964.
Irani, B., Mansberger, A. R., Att.\r, S.,
Masaitis, C, Kirby, W. H., and Cowley,
R. A. : II, The Behavior of Fibrogen in
Clinical Septic Shock. In press.
Iraxi, B., Kirby', W. G., Attar, S., AIasaitis,
C. A., Mansberger, A. R., and Cowley,
R. A.: Ill, The Effect of Septic Shock in
Clotting Time in Humans, Ann. Surg. In
press.
JiTi. R., Lixberg, E. J., Sacks, M., and Spurl-
ixG, R. : Failure of Thymectomy in the Treat-
ment of Acute Human Leukemia, Blood. In
press.
Kaestner, R., C.-\rski, T., Fraxzone, J.,
Lewitixn, a., Cowley, R. A., Esmond,
\\'. G., Hurdle, E., and Baker, B. : Re-
liability Engineering for Open Heart Surgery,
Bull. Sch. Med. Uni'j. Maryland, Oct., 1964.
Kirby, W. H., Mansberger. A. .\,. Attar, S.,
Masaitis. C, and Cowley, R. A.: The Effect
of Hemorrhagic Shock on Clotting Time in
Humans, Ann. Surg. In press.
Kirby, W. H., Masaitis, C, Irani, B., Mans-
berger, A. R., -Attar, S., and Cowley, R. A. :
II, The Behavior of Fibrogen in Clinical
Septic Shock. In press.
Kirby, \V. G., Attar, S., Iraxi, B., Masaitis,
C. A., Mansberger, A. R., and Cowley,
R. A.: Ill, The Effect of Septic Shock on
Clotting Time in Humans, Ann. Surg. In
press.
Laxzi, J., McLaughlix, J., Linberg, E. J.,
and Cowley, R. A. : Traumatic Intercostal
Arteriovenous Fistula : Case Report, Ann.
Surg., 161: 218, 1965.
Lewitixx, A., Cowley, R. A., Esmond, W. G.,
Fraxzone, J., Carski, T., Kj\estxer, R.,
Hurdle, E., and Baker, B. : Reliability Engi-
neering for Open Heart Surgery, Bull. Sch.
Med. Univ. Maryland, Oct., 1964.
Lixberg, E. J., Bloedorn, F. G., Cowley, R. A.,
CucciA, C. A., Mercado, R., and Wizenberg,
M. J. : Preoperative Irradiation in Broncho-
genic Carcinoma, Anicr. J. Roentgen. 92: 77,
1964.
Linberg. E. J., and !Max"sberger, A. R. : First
Rib Resection for Distal E.xposure of Sub-
clavian Vessel, Surg. Gyncc. Obstet., 120:
579, 1965.
Linberg, E. J., McLaughlin, J., Lanzi, J., and
Cowley, R. A. : Traumatic Intercostal Ar-
teriovenous Fistula: Case Report, Ann. Surg.,
161:218, 1965.
Linberg, E. J., Cowley, R. A., Bloedorn, F.,
and Wizenberg, M. J. : Bronchogenic Carci-
noma Further Experience with Preoperative
Irradiation, /. Thorac. Cardiov. Surg. In
press.
Linberg, E. J., Jiji. R., Sacks, M., and Spurl-
ING, R. : Failure of Thymectomy in the Treat-
ment of Acute Human Leukemia, Blood. In
press.
Linberg, E. J., Singleton, R., Hankixs, J.,
Lyons, J., and Cowley, R. A. : Congenital
Anomalies of the Pulmonary Arteries, /.
Thorac. Cardiov. Surg. In press.
Linberg, E. J., and Hawkins, J. : Tracheo-
bronchial Obstruction Caused by an Aberrant
Left Pulmonary Artery. In preparation.
Lyons, J., Hankins, J., Singleton, R., Lin-
berg, S. J., and Cowley, R. A. : Congenital
/»/v. 1966
HEALTH SCIENCES LIBRARY,
UNIVERSITY OF MARYLAND
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
Anomalies of the Pulmonary Arteries, /.
Thorac. Cardiov. Surg. In press.
Mansberger, a. R., and Linberg, E. J. : First
Rib Resection for Distal Exposure of Sub-
clavian Vessels, Surg. Gynec. Obstct., 120:
579, 1965.
Mansberger, A. R., Attar, S., Beech, A., and
Cowley, R. A. : The Possible Relationship of
Certain Chromatographic Changes to Coagu-
lation Aberrations in Hypotensive Patients,
/. Trauma. 5: 90, 1965.
MA^fSBERGER, A, R., Attar, S., Blair, E.,
Cowley, R. A., and Buxton, R. : The
Therapy of Refractory Shock, Ann. Surg.
In press.
Mansberger. A. R., Attar, S., Ollodart, R.,
McLaughlin, J., and Cowley, R. A. : A
Physiologic Approach to the Correction of
Hypotension, Ann. Surg. In press.
Mansberger, A. R., Attar, S., Kirby, W. H.,
Masaitis, C, and Cowley, R. A. : The Effect
of Hemorrhagic Sliock on Clotting Time in
Humans, Ann. Surg. In press.
Mansberger, A. R., Attar, S., Irani, B.,
Masaitis, C, Kirby, W. H., and Cowley,
R. A.: II, The Behavior of Filirogen in
Clinical Septic Shock. In press.
Mansberger, A. R., Masaitis, C. A., Irani,
B., Kirby. W. G., Attar, S., and Cowley,
R. A.: Ill, The Effect of Septic Shock on
Clotting Time in Humans, Ann. Surg. In
press.
Mansberger, A., and McLaughlin, J.: The
Treatment of Shock. Submitted for publi-
cation, Ann. Surg.
Masaitis, C, Kirby, W. H., Mansberger,
A. R., Attar, S., and Cowley, R. A. : The
Effect of Hemorrhagic Shock on Clotting
Time in Humans, Ann. Surg. In press.
Masaitis, C, Irani, B., Mansberger, A. R.,
Attar, S., Kirby, W. H., and Cowley, R. A. :
II, The Behavior of Fibrogen in Clinical
Septic Shock. In press.
Masaitis, C. A., Irani, B., Kirby, W. G.,
Attar, S., Mansberger, A. R., and Cowley,
R. A.: Ill, The Effect of Septic Shock on
Clotting Time in Humans, Ann. Surg. In
press.
McLaughlin, J., Linberg, E. J., Lanzi, J., and
Cowley, R. A. : Traumatic Intercostal Ar-
teriovenous Fistula: Case Report, Ann. Surg.,
161: 218, 1965.
McLaughlin, J., Ollodart, R., Mansberger,
A. R., .Attar, S., and Cowley, R. A. : A
Physiologic Approach to the Correction of
Hypotension, Ann. Surgery. In press.
McLaughlin, J., and Mansberger, .\. : Tlie
Treatment of Shock, submitted for publication,
.Ann. Surg.
McLaughlin, J., and Strauch. M.; Renal
Function in Septic Shock. In preparation.
McLaughlin, J.: Ventricular Fibrillation from
Digitalis Therapy : Successful Results of 99
Episodes of Ventricular Asuptole. In prepara-
tion.
Mercado, R., Cuccia, C. A., Cowley, R. A.,
Bloedorn, F. G., Linberg, E. J., and Wizen-
berg, M. J. : Preoperative Irradiation in
Bronchogenic Carcinoma, Aincr. J. Roentgen,
92: 77, 1964.
Michaelis, M., Esmond, W. G., Blair, E.,
Cowley. R. A., .Attar, S., and Ollodart, R. :
Prevention and Treatment of Shock by Hyper-
baric 0.\ygenation, Ann. N.Y. Acad. Sci.,
117: 673, 1965.
Michaelis, M., Cowley, R. .\.. Esmond, W. G.,
Henning. G., Blair, E., and Attar, S. : The
Effect of Hyperbaric O.xygenation (OHP)
on Three Forms of Shock — Traumatic,
Hemorrhagic and Septic, /. Traiinui, 4: 652,
1964.
Nygren, E., Blair, E., and Cowley, R. ,\. :
A Spiral Wire Technique for Producing
Gradually Occlusive Coronary Thrombosis,
/. Thorac. Cardiov. Surg., 48: 476-485, 1964.
Ollodart. R., Michaelis, M., Esmond, W. G.,
Blair, E., Cowley, R. A., and Attar, S. :
Prevention and Treatment of Shock by Hyper-
baric O.xygenation, Ann. A'.)'. Acad. Set., 117:
673, 1965.
Ollodart, R., Blair, E., .Attar, S., Esmond,
W. G., and Cowley, R. A. : The Effect of
Hyperbaric Oxygenation on Bacteremic
Shock, Circulation, 29: 135-139, 1964.
Ollodart. R., and Blair, E. : High Pressure
Oxygen as an .Adjunct in Experimental
Bacteremic Shock, J. A.M. A.. 191: 736-739,
1965.
Ollodart, R., Mansberger, A. R., Attar, S.,
McLaughlin, J., and Cowley, R. A. : A
Physiologic Approach to the Correction of
Hypotension, Ann. Surg. In press.
Ollodart. R., Blair, E., .Attar. S., and Cowley,
R. A. : Hyperbaric O.xygenation in the Treat-
ment of E.xperimental Shock, Aincr. J. Surg.
In press.
;■',./. .'ii. A',-. 3
MEniCAI. SCHOOL SECTIOX
I ii i.ouAKT, R., Bi.AiR, E., CowiEv, R. A., and
IIexnmng, G. : Hypoxia Resulting from Coli-
I'orm Infections in Animals, A'li//. Acad.
Sci. In press.
I
I Sacks. M., Jiji. R.. Linhkkg. E. J., and .Si'im.-
i.\"G. R. : Failure of Thymectomy in the Treat-
ment of Acute Human Leukemia, Blond. In
press.
! Sl.NCLETO.V. R.. LiNBERG, E. J., HaNKI.V.S. J.,
' Lyons. J., and Cowley, R. A.: Congenital
Anomalies of the Pulmonary Arteries. /.
Thonic. Cardial: Surg. In press.
Spurling. R., Sacks. M., Jiji, R., and Lix-
BERG, E. J.: Failure of Thymectomy in the
I Treatment of .\cutc Human Leukemia, Blood.
In press.
I Straucii. M.. and McLaughlin, J.: Renal
I Function in Septic Shock. In preparation.
Tait, M. K., Cowley, R. A., and Blair. E. :
Lactacidemia from Septic Shock in Man,
Amcr. Surg. In press.
WizEXBERG, M. J., Mercado, R., Cuccia, C. A.,
1 Cowley, R. A., Bloedorx, F. G., and Lix-
BERG. E. J.: Preoperative Irradiation in
I Bronchogenic Carcinoma, Amcr. J. Roentgen.,
\ 92: 7, 1964.
! WizEXBERC, M. J.. Bloedorx, F. G., Cowley,
R. A., and Lixberg. E. J.: Bronchogenic
i Carcinoma Further Experience with Pre-
I operative Irradiation, /. Thorac. Cardiov.
Surg. In press.
Division of Urologic Surgery
Aledia, F. T., and Young, J. D., Jr. : Further
Observations on Flank Cutaneous Ureter-
ostomy and Transureteroureterostomy as a
Means of L'rinary Diversion, presented at
Meeting of American Association of Genito-
urinary Surgeons, May, 1965, New Orleans.
To be published in Trans. Amcr. Ass. Geni-
tourin. Surg.
Beyer, O., Youxg, J. D., Jr., Galleher, E. P.,
Jr., Bloedorn, F. G., and Dou, J. : Supravolt-
age Irradiation Followed by Cystectomy, J.
Urol. In press.
Bloedorn, F. G., Beyer, O., Young, J. D., Jr.,
Galleher, E. P., and Dou, J. : Supervolt-
age Irradiation Followed by Cystectomy, /.
Urol. In press.
Dou, J., Bloedorx, F. G., Beyer, O., Young,
J. D., Jr., and (iAlleher, E. P., Jr.: Supra-
voltage Irradiation Followed by Cystectomy,
J. Urol. In press.
Galleher, E. P., Jr., Young, J. D., Jr., Beyer,
O., Bloedorn, F. G., and Dou, J. : Supervolt-
age Irradiation Followed by Cystectomy, /.
Urol. In press.
Galleher, E, P., Jr., McCuxe, W. R., and
Wood, C. : Leiomyoma of the Kidney in a
Newborn Infant, /. Urol., 91 : June, 1964.
Kiser, W. S., and Young. J. D., Jr.: Ob-
struction of the Lower Ureter by Aberrant
Blood N'essels, presented at Meeting of Mid-
Atlantic Section of A \] A, Williamsburg,
X'irginia, Nov., 1964, /. Urol. Accepted for
publication.
Maxsberger, A., Jr., and Young, J. D., Jr. :
Ammonia Levels as an Aid to Diagnosis of
Urinary Extravasation, presented at Meeting
of Mid-Atlantic Section A U A, Williamsburg,
Virginia, Nov., 1964, /. Urol. Accepted for
publication.
McCuxE, W. R., Galleher, E. P., Jr., and
Wood, C. : Leiomyoma of the Kidney in a
Newborn Infant, /. Urol., 91: June, 1964.
Wood. C, Galleher, E. P., Jr., and McCune,
W. R. : Leiomyoma of the Kidney in a New-
born Infant, /. Urol., 91: June, 1964.
Young, J. D., Jr., Galleher, E. P., Jr., Beyer,
O., Bloedorn, F. G., and Dou, J. : Supravolt-
age Irradiation Followed by Cystectomy, /.
Urol. In press.
Y'ouNG, J. D., Jr., and Kiser, W. S. : Ob-
struction of the Lower Ureter by Aberrant
Blood Vessels, presented at Meeting of Mid-
Atlantic Section of A U A, Williamsburg,
Virginia, Nov., 1964, /. Urol. Accepted for
publication.
Y'oUNG, J. D., and Mansberger, A., Jr.: Am-
monia Levels as an Aid to Diagnosis of
Urinary Extravasation, presented at Meet-
ing of Mid-Atlantic Section A U A, Williams-
burg, Virginia, Nov., 1964, /. Urol. Accepted
for publication.
Young, J. D., Jr., and Aledia, F. T. : Further
Observations on Flank Cutaneous Ureter-
ostomy and Transureteroureterostomy as a
Means of Urinary Diversion, presented at
Meeting of American Association of Genito-
urinary Surgeons, New' Orleans, May, 1963.
To be published in Trans. Amcr. Ass. Gcni-
tourin. Surg.
July, 1966
xli
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Vol. M. -V... 3
ALUMNI ASSOCIATION
SECTION
OFFICERS
President
Howard B. Mays. M.D.
President-Elect
John O. SllARRKTr. M.I),
Vice-Presidents
I!f.x;ami.n M. SiEix. .M.D.
I'atricia Dodd, M.U.
Raymond M. Cvxxixgham. M.D
Aliiiiiiii Day, May 6, 1966
Ihc annual meeting and scicntilk pro-
gram of the Medical Alumni Association
was held in 1966 in conjunction with the
bi-annual meetings of the University Hos-
pital Medical and Surgical Associations
which included the University of Maryland
Medical Association, the Douglass Ob-
stetrical and Gynecological Society, the
Bradley Pediatric Society, and the Uni-
versity of Maryland Surgical Society.
Scientific programs were under the super-
vision of committees of these organiza-
tions. Those registering for the Alumni
Day activities included the following:
Kardasu. M.D.
Class of 1908
Executive Director
Wn.i.iAM H. Tritl
Executive Secretary
.Mrs. Locise Girkix
Board of Directors
William H. Kammer, Jr., M.D.
Robert B. Goldstein. M.D.
JoHX D. Yoixc. M.D.
Harry C. Bowie. M.D.
Theodore Stacy. ^r.D.
WilfordH.To\vxshexd..Tr.,M.D.
Joiix C. Di-MLER. Sr.. M.D.
\V. Kexxeth Maxsfield, M.D.
T. Howard Fraxz. M.D.
C. Parke Scaeboroigh, M.D.
(rx-officio)
Nominating Committee
J. Howard Fraxz. M.D.
(cx-offich)
C. Parke Scarborough, M.D,
(cx-officioj
D. McClelland Dixon, M.D.
James R. K.^rns, M.D.
Edward F, Cotter, M.D.
Lester D. Norris
Class of 1910
John G. Runkel
Class of 1911 (P&S)
John F. Hogan W. T. Gocke
Class of 1914
Austin H. Wood
Class of 1915
W. R. McKenzie
Class of 1916
Geo. A. Bawden
Edward H. Benson
Chas. R. Brooke
B. Bruce Brumbaugh
Henry F. Buettner
Michael E. Cavallo
Lucien R. Chaput
Harry Goldmann
Bowers H. Growt
Chas. H. Lupton
Geo. McLean
Vincent J. Oddo
Guy R. Post
Chas. A. Reifschneider
F. Fred Ruzicka
Wilbur T. Shirkey, Jr.
Maurice C. Wentz
Class of 1917
Louis Krause
Howard B. Mays, M.D.
(ex-officio)
Class of 1918
John M. Nicklas
Representatives to
Faculty Board
To be named.
C3-year term began June, 1965)
C, Parke Scarborough, M,D.
Howard B, Mays, M.D.
Class of 1921
Thomas O'Rourk F. S. Shubert
Class of 1922
Joseph S. Stovin T. N. Wilson
Class of 1925
Samuel S. Glick Joseph Nataro
July. 1966
xliii
^ULLETIX OF THE SCHOOL OF MEDICIXE. U.Ml'ERSITV OF MARYLAND
Class of 1926
Solomon B. Zinkin
John A. Askin
Margaret B. Ballard
Henrv DeVincentis
David M. Helfond
Louis T. Lavy
H. E. Levin
Joseph Levin
A. H. Finkelstein
Walter C. Merkel
William C. Polsue
Albert A. ({osenberg
William Schuman
Elizabeth Sherman
Frank Spano
Class of 1929
Leroy S. Heck George H. Yeager
Class of 1930
Zack A. Owens L. R. Schoolman
of 1931
Waldo B. Movers
E. A. Schimunek
Wm. M. Seabold
Harry S. Shelley
Arthur G. Siwinski
Michael Skovron
R. A. Stevens
W. A. \anOrnier
Henry Wigderson
Class
E. L Baumgartner
W. C. Boggs
Donald B. Grove
Samuel A. Feldman
K. M. Hornbrook
Abraham Karger
Max Kaufman
Walter Kohn
Jerome L. Krieger
Alston G. Lanham
Class of 1932
Harry C. Hull Louis F. Klimes
Arthur Karfgin Stephen L Rosenthal
Class of 1934
Robert W. Farr John N. Snyder
Reuben Leass
Class of 1933
Edward F. Cotter Howard B. Mays
John Godbey Karl F. .Mech
Josiah A. Hunt L. K. Woodward, Jr.
Class
Milton Bernstein
Harry C. Bowie
McClelland Dixon
Wm. Greifinger
J. W. Gordner
Ben Isaacs
C. Henrv Jones
W. E. Karfgin
Saul Karpel
Howard T. Knobloch
Louis J. Kolodner
Robert M. Lowman
of 193G
W. K. Mansfield
James P. .Morgan
Benjamin B. Moses
Jos. R. .Mverowitz
S. D. Pentecost
Milton H. Stapen
Morris H. Stern
Lsaac Terr
Lawrence Tiernev
Gibson J. Wells
Nathan Wolf
Joseph G. Zimring
Class of 1937
S. T. R. Revell, Jr. Isadore Kaplan
Thomas .\bbott
C. Parke Scarborough
Class of 1938
John A. Wagner T. E. Woodward
Class of 1939
Henry \. Briele Wm. H. Kammer, Jr.
R. M. Cunningham
Class of 19-fO
Lester H. Caplan H. P. >Iaccubbin
Edwin O. Daue, Jr. Ross Z. Pierpont
Benj. H. Inloes. Jr.
James R. Karns
Class of 1941
Pierson M. Checket Christian F. Richter
LeRoy G. Cooper
Joseph V. Crecca
yi. L. De Vincent is
Anthony F. Di F^aula
Julius Gelber
T. F. Lusbv
E. L. Seigman
E. P. Shannon
Joseph C. Sheehan
Tracv X. Spencer
J. H. Walker
Elizabeth B. Sherrill
Ydalia Ortiz Freeman John D. Young, Jr.
C. E. Pruitt
Class of 1943
Elizabeth Acton H. B. Parry
Ruth Baldwin David R. Will
Class of 1944
John M. Bloxom, HI W. C. Ebeling
R. C. Cloninger Donald Mintzer
R. A. Cowley
Class of 194.5
John M. Dennis Paul R. Myers
Joseph B. Ganey Stanley A. Steinbach
Class
Robert E. Bauer
Harold V. Cano
Thomas B. Connor
Paul E. Frye
John R. Gamble, Jr.
William D. Gentry
James J. Gerlach
H. William Gray
Duane Greenfield
Edwin O. Hendrickson
Jay Hansen
Charles W. Hawkins
Charles A. Hefner
Harry E. Hill
E. R. Jennings
Herbert J. Levickas
Class of 1947
Arlie R. Mansberger Jose G. Valderas
William R. Post
Class of 1948
George V. Hamrick Norman Tarr
Katharine V. Kemp William S. Womack
Kyle Y. Swisher
Class of 1949
Edmund B. Middleton
Class of 1950
Paul F. Richardson Bate C. Toms, Jr.
Class of 1951
E. M. Beardsley Mario Garcia-Palmieri
William G. Esmond Henry D. Perry
Charles K. Ferguson H. Gray Reeves
F. Sidnev Gardner, Jr. C. P. Watson
Leo H. Ley, Jr. H. P. Wheelwright
Donald J. Myers
Class of 19.52
Michael J. Foley Richard Sindler
Class of 19.53
William S. Kiser
of 1946
Ravmond L. Markley
C. E. McWilliams
Earl R. Paul
John C. Rawlings
Ralph A. Reiter
R. C. Rossberg
F. A. Shallenberger,
Jr.
Edward P. Smith. Jr.
James A. Sewell
Clint Stallard, Jr.
Leon Toby
James A. Vaughn, Jr.
Irl J. Wentz
Joseph Workman
xliv
{ ■»/.
-V-*. 3
.ILL MM .ISSOCIATIOX Sl-X lldX
Clas
Robert S. Donoho
Robert IJ. Goldstein
of 1!I54
John F. Hartman
Harold U. Weiss
Class of I'JoB
John B. Littleton
(.'. Patrick Laushlin
Gerald Maggid
Joseph S. McLaughlin
Lamont Osteen
Gerald Shuster
Paul V. Slater
1). G. Anderson
Richard Belgrad
T. R. Carski
James T. Estes
R. A. Finegold
Alfred W. (Jrigoleit
Webb S. Hersperger
Albert N'. Kanner
Class of 1957
Milton L. Engnoth Carl Jalenko, III
\incent J. Fiocco, Jr. David P. Largey
Class of 1958
Thomas Crawford Philip J. Ferris
R. J. Donovan, Jr. R. H. Johnson
Class of 1959
Robert J. Dawson Hans R. Wilhelmsen
R. J. Thomas
Class of 1960
Neil A. Robinson
Class of 1961
Carl F. Berner G. C. Kempthorne
Jams J. Cerda Michael B. A. Oldstone
Francis A. Clark. Jr. George E. Urban, Jr.
Class of 1962
Ian R. Anderson George C. Schmieler
Class of 1963
Robert M. Byers Philip A. Insley, Jr.
Class of 1964
Dominic H. Culotta Marston A. Young
Class of 1965
Fred V. Cole, Jr. A. H. Khazei
NON ALUMNI REGISTERED AT 1966
MARYLAND MEDICAL REUNION
Safuh .\ttar
Baltimore, Md.
John L. Atkins
York, Pa.
Samuel P. Bessman
Baltimore, Md.
Emil Blair
Baltimore, Md.
J. Edmund Bradley
Brewster, Mass.
Otto C. Brantigan
Baltimore, Md.
Milton S. Grossman
Ellicott City, Md.
E. H. LaBrosse
Ellicott City, Md,
Douglas R. Cain
Baltimore, Md.
Paul M. DiGiorgi
New York, N. Y.
Bahran Erfan
Randallstown, Md.
Frank H. J. Figge
Baltimore, Md,
Michael K, Finegan
Baltimore, Md.
C. Thomas Flotte
Baltimore, Md.
William B. Rever, Jr.
Baltimore, ^Id.
Beverly L. Reynolds
Dallas, Texas
Allan Ronald
Seattle, Wash.
(i. Edward Simons, Jr.
Seattle, Wash.
Conover Talbot
Chicago, 111.
Jose Valdes
Cumberland, .Md.
Yu Chen Lee
Baltimore, Md.
William I). L\nn
Baltimore, Md.
Fitzhugh Mullins
Louisville, Ky,
Neil Novin
Baltimore, Md.
Fausto .M. Prezioso
Timonium, Md.
The program began officially at 8:45 A.M.
on Friday, May 6, 1966 with the welcoming
address by Dr. William S. Stone and an
address entitled ""Medicare"" delivered by
Mr. Robert M. Ball, Commissioner of the
Social Security Administration, an address
of great interest to the visiting physicians
present. This was followed immediately by
sectional scientific sessions, the morning be-
ing concluded with the annual alumni busi-
ness meeting in Chemical Hall with Dr. C.
Parke Scarborough, President of the Medical
Alumni Association, presiding. At this meet-
ing, it was intended to present the Annual
Award to Dr. T. Nelson Carey; however,
President Scarborough announced that he
had had the honor of presenting the medal
to Dr. T. Nelson Carey at his bedside in the
Mercy Hospital before Dr. Carey died, A
moment of silence was observed.
This was then followed by the minutes
of the previous meeting, the financial report
and the annual election of officers. Dr.
Howard B. Mays succeeded to the
presidency.
Minutes of Annual Meeting
The annual meeting of the Medical
Alumni Association, University of Mary-
land took place in Chemical Hall on May
6, 1966. The meeting was called to order
by the President, Dr. C. Parke Scarborough,
who welcomed back the members of the
Alumni Association. He reported briefly
on the condition of the Association, stating
that the Association is now in a posiion
to and are making plans for setting up a
long hoped for Curriculum Vitae. The
Board of Directors are making new plans
for reunions at meetings about the country
in connection with Medical and Scientific
Meetings. It is believed that the biennial
July, 1966
xlv
CAMERA VIEWS
ALUMNI WEEK
1966
fl'
/.
Drs. Robert Farr, Arthur Karfgin, and Lewis K. Woodward.
Drs. Theodore Kardash. Howard B. Mays, John O. Sharrett, and W. E. Karfgin
/»/v, 1966
xlvii
BULLETIN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF MARYLAND
meetings with the Hospital Societies are
working out very successfully. Dr. Scar-
borough also stated that the Board of
Directors has been working diligently.
Dr. Scarborough introduced Dean
William S. Stone who emphasized the re-
lationship between Administration and the
Alumni Association. He believes we are
developing a relationship that is needed.
The University is going forward in a tre-
mendous way and is now the tenth largest
in the USA. The campus in Catonsville will
in the near future have an enrollment of
25.000. Our relationship must be very close.
At the moment a Dean of the Graduate
School at College Park is being selected.
Dean Stone feels that all this planning is
proceeding in a healthy way. He hopes
that the Alumni will work along with Ad-
ministration.
The Treasurer's Report was given by Dr.
Karfgin who was happy to announce that
we are on solid ground financially. On
Alumni Day. June 3, 1965, he had an-
nounced that at the beginning of that
fiscal year May 1, 1965, we had in our
checking account at Maryland National
Bank $ 1,644.31
in our savings account
at Maryland National
Bank 5,176.40
in our funded reserve at
Eutaw Savings Bank . 16,524.88
and in our Student Loan
Fund at Balto. Fed.
Sav. & Loan 1,555.27
as well as Petty Cash in
the amount of 75.22
A total of $24,976.08 plus
student loans receiv-
able in the amt. of 4,900.30
which together total $29,876.38
At the close of the fiscal year, April 30.
1966 we have the following to report:
in our checking account
at Maryland National
Bank $12,833.48
in our savings account
at Maryland National
Bank 12,358.93
in our funded reserve at
Eutaw Savings Bank 18,306.71
in our Student Loan
Fund at Balto. Fed.
Sav. & Loan 1,720.04
as well as Petty Cash
in the amount of 50.00
A total of $45,269.16 plus
student loans receiv-
able in the amt. of 4,900.30
which together total for
the end of this fiscal
year $50,169.46
His report went on to explain that a great
part of this money came in recently to
pay for banquet and Alumni Day affairs.
However the number of paid up members
of the Association exceeds the number paid
on this date on our previous best year.
Dr. Scarborough congratulated both our
present and past treasurers for their ex-
cellent efforts and results.
At the request of Dr. Scarborough the
Necrology was read by Dr. William H.
Triplett which began with the following
poem, most appropriate:
When I have bided here my little while.
Serving my day as destiny hath planned.
In my own way as best I understand,
May I go calmly to my last deep sleep.
And as the purple shadows o'er me creep
Behold the Great Eternal with a smile;
And may that smile be as a Good Night's
kiss
To loves that know no better world than
this.
■ — Selected.
NECROLOGY ROSTER
Kemp, Howard M.
Hornstein, Abraham
Quinn. John Francis
O'Connor, Michael J.
Bamberger. Beatrice
Schmuckler, Jacob
Doyle. John Henry
BMC
1911
1911
BMC
1906
BMC
1906
1931
1926
P&S
1902
Vol. 51.
No. 3
.^LUMXI ASSOCIATION SHCTIOX
Ciill. Joseph 1-Al\\;ird
1949
/oiger, Samuel
1930
Reddig, Clarence M.
1917
Coleman. Joseph
1904
Mullan. Eugene H.
1903
Murgatro>d. George W.
BMC
1910
Ganll. Harry B.. Jr.
1909
Bulla. Jefferson D.
P&S
1888
tKillagher. William E.
1917
Reiger. Ernest M. G.
P&S
1915
Sahislon. Frank
1918
Bishop. George W.
1914
Seelinger, Harr\ R.
1910
Harold. John A.
P&S
1903
Graham. Archibald W.
1905
Skaggs. James W.
1920
Sirak, William W.
1913
C ohn. Charles W,
P&S
1908
(Jiiintero. Ernesto
1920
( haffee. Orel N.
P&S
1906
c loodhand, Charles L.
1934
(.oldstein, Albert E.
P&S
1912
( .irey. T. Nelson
1927
\ ick. Clyde W.
P&S
1905
Lehnert. Ernest C.
1902
Stonestreet. Washington W.
1906
Smith, Ziba L.
P&S
1906
McConnell, Harvey R.
1924
Russell. John C.
1935
Riddick. Willard J.
1905
DeCormis. Joseph L.
1903
Kirk. George B.
BMC
1898
( .ifritz. Edward A.
1918
1 opez. Boccanegra
1916
LeBlanc. William
P&S
1905
Schumacher. Fred C.
P&S
1905
Miller. George A.
P&S
1905
Roberts. Silvia J.
P&S
1912
McMullan. Joseph F.
(Dec.)
1943
Pfeil. E. Thornton
(Dec.)
1943
Levin. Milton
1934
Beck. Foster A.
1916
Cohen. Phillip P.
1929
Doshay. Lewis J.
1922
Davidov. Nathan J.
1920
Crouch, Thomas D.
1910
Lewis, Taylor
1904
Kunkowski, Mitchell F.
1937
Ridgely, Irwin O.
1918
Lennon. William E.
1925
Alexander. Samuel A.
1913
Houston. Robert E.
1904
Miller, Herman S.
P&S
1911
Eanet, Paul
1926
Rousseau, James P.
1918
Varney. William H.
1928
Demarco, Vincent J. 1915
Winslow, Fitz R. 1906
Macke. Clarence E. 1918
Pillsbury. Harold C. 1921
Brown. Leo T. 1925
Stone. William C. BMC 1903
Dominguez, Thomas M. 1916
Steele, Byron W. P&S 1914
Langeluttig, H. Vernon 1931
Granoff. Jerome F. 1924
Robertson. Joseph R. 1910
The president asked Dr. Gibson J. Wells
to read the report of the Nominating Com-
mittee, and this report follows: John O.
Sharrett. M.D., President-elect, Benjamin
M. Stein, M.D., Vice-President. Patricia
Dodd, M.D., Vice-President. Raymond M.
Cunningham. M.D.. Vice-President. Walter
E. Karfgin. M.D.. Treasurer. Theodore
Kardash, M.D.. Secretary. Wilford H.
Tovvnshend, Jr.. M.D., Member of Board of
Directors, W. Kenneth Mansfield, M.D.,
Member of Board of Directors, and John
C. Dumler. Sr.. Member of Board of
Directors. The president asked that this
report be accepted. A motion was made,
and seconded that the secretary cast a
ballot for these nominees. Motion carried
unanimously.
The president asked for nominations
from the floor for three members of the
Nominating Committee to select nominees
for ne.xt year. Dr. D. McClelland Dixon, Dr.
James R. Karns, and Dr. Edward F. Cotter
were nominated and a motion was made
that nominations be closed. Motion was
seconded and carried unanimously.
Dr. Scarborough called for the report of
the Student Loan Committee. Dr. Gibson
J. Wells" report follows:
May 6, 1966
Subject: Report of Student Loan Fund
Committee, To: Annual Business Meeting
1. The Student Loan Fund was estab-
lished in its present form in 1958. Loans
are made only upon recommendation of
the Dean"s Committee on Scholarships and
Loans, and approval by the Medical Alumni
Association Student Loan Committee.
2. The recipient is not required to exe-
cute any note or other evidence of legal
obligation but does acknowledge, over his
/»/v, 1966
xlix
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
signature, that a loan in the amount of
( X ) dollars has been received and a moral
obligation is thus assumed.
3. To date there has been received from
donors to the Fund a total of $6,309.71 and
a total of $310.63 interest has been earned
and credited which totals receipts of
$6,620.34.
4. Loans, 14 in number, have been made
to 13 individuals totaUng $4,900.30 which
leaves a balance in the Fund of $1,720.04.
5. The first loan was made April 27, 1959
and the last, October 25, 1963. One re-
cipient has made inquiry relative to repay-
ment and has been fully advised concerning
the simple procedure of remittance but as
of the date of this report all loans are still
oustanding.
6. It is apparent that the liberality of our
federal government with loans is more at-
tractive to our student body in need of
financial asistance and this is probably due
to the fact our Fund has a fixed maximum
of $500.00.
7. A loan guaranteeing first semester
tuition has been approved and will be de-
livered upon application.
Gibson J. Wells, M.D., Chairman
Frank K. Morris. M.D.
Maurice Reese, M.D.
Now the time arrived when the Honor
Award is usually presented. Dr. Scar-
borough read the reply received from Dr.
T. Nelson Carey when he was informed
that he had been chosen to receive this
award. He then reminded the members
present of the quality of greatness that Dr.
Carey possessed and of the significant
service he had given his school. He said,
"Dr. Carey has been called a doctor's
doctor and he has possibly been physician
to more Baltimore doctors than any man
in Baltimore." He then told the story of
the presentation made to Dr. Carey the day
before his death occurred. Dr. Carey
showed it to all who came in that day
and Mrs. Carey showed it to others.
A memoriam written by Dr. William H.
Triplett at the request of the Board of
Directors was read.
In Memoriam
In the passing of Dr. T. Nelson Carey
the silent hall of Death received a kind,
considerate physician, one loved by his
patients and friends, and his professional
associates lost a revered and loyal teammate.
The interests and activities of Dr. Carey
covered a wide range. Although burdened
with a progressive physical handicap his
courage and determination was sufficient to
carry him forward into a busy private
practice together with extensive hospital
work, and closely allied with these, both
in time and space, his ever present interest
in teaching both undergraduates and house
officers.
The foundation upon which he built a
useful life was made up of many different
segments chief among them being intelli-
gence, courage, compassion, understanding,
honesty, sincerity, benevolence and loyalty.
With it all his sense of humor was never
failing and a ready smile of greeting an
index to his character.
Posterity will give its proper meed of
praise to Nelson Carey. The good deeds he
spread over his chosen field will live on.
Members stood again to express their
great appreciation of this, our recipient of
the 1966 Honor Award.
An announcement was made to the effect
that when the 1,000 copies of A University
Is Born by Dr. Margaret B. Ballard are sold
there will be no more available. All were
asked to get their copies before leaving the
city.
Election of officers took place, the secre-
tary being asked to cast a unanimous ballot
for all of the nominees presented earlier by
the nominating committee.
Theodore Kardash, M.D.
Secretary
Following the Annual Meeting of the
Medical Alumni Association, the customary
noon luncheon was served to visitors. A
cocktail party was held at the Lord Balti-
more Hotel, followed by the annual Alumni
banquet.
\\,l. 51. A'y. -?
I
TREASURERS REPORT OF ALUMNI ASSOCIATION, 1966
Annual Financial Slatcnitiil - Mav I. 1 1>6."> - A|»iil 30, 1966
Opening Balance, May 1, 1965:
Marxlaiul National Bank (C'lictking Account) SI .644.^1
Mar\lancl National Bank — (Sa\ings AccomU ) 5,176.40
iuitaw Sa\ings Bank — (Funded Reser\e) 16,524. iSS
Baltimore l-"edcral Sa\-ings & Loan
iStiident Loan I'und) 1 ,555 . 21
n.\L.\NCK IN n.\NKs 824,900.86
Plus Student Loans Receivable 4,900.30
v$29,801.16
Receipts Deposited, May 1, 1965 - April 30, 1966
Dues S19.567.00
Bulletin 8,379.00
Alumni Da\' — Includes parts of 1965 and 1966 5,310.50
"—Ladies' Tours (all 1966) 217.00
Interest and Dividends 929. 13
Individual Contributions 1 ,915.00
.Miscellaneous 293.02 836,611.6 =
866,412.81
Disbursements, May 1, 1965 - April 30, 1966
Salaries— Mrs. Girkin S 3 , 1 78 . 52
—Extra Help 227 . 64
Bulletin 5,000.00
District Director Internal Revenue 922.01
Comptroller, State of Mar\land 114.66
Printing and Office Supplies 482 . 73
Postage 1,070.40
Alumni Day 4,532.66
Honorarium 500 . 00
Miscellaneous 214.73 816,243.35
Closing Balance for April 30, 1966 850 , 169 . 46
Closing Balance, April 30, 1966
Maryland National Bank— (Checking Account) 812,833.48
Maryland National Bank — (Savings Account) 12,358.93
Eutaw Savings Bank — (Funded Reserve) 18,306.71
Baltimore Federal Savings & Loan
(Student Loan Fund) 1 , 720 . 04
Petty Cash 50 . 00
B.\LANCE IN BANKS 845 , 269 . 16
Plus Student Loans Receivable 4 , 900 . 30
850,169.46
Pre-coiumencement and Dean's Day
Ceremonies honoring the Class of 1966
featured the Pre-commencement Convo-
cation of the 159th year of the School of
Medicine held on the campus at 2 P.M..
Friday June 3, 1966.
Following the academic procession, the
Invocation was delivered by Dr. James C.
Thomson, Jr., Campus Ministry Coordi-
nator. Dr. Albin O. Kuhn, Vice President
of the University for the Baltimore
Campuses, delivered a brief greeting to the
graduating classes, this being followed by
vocal selections by the Glee Club of the
School of Nursing.
Dean Stone then presented a group of
candidates for academic Honors which are
listed below:
Dr. Leonard M. Hiimmell Memorial Award,
Gold Medal — Outstanding qiialificatioiis in
Internal Medicine
Kurt Porter Sligar
Dr. A. Bradley Gaither Memorial Prize, for
excellence in Genito-Vrinary Surgery
Albert Truman Miller
Robinson Dermatologic A ward — For excellence
in Dermatology
Irvin Murray Sopher
Dr. Milton S. Sacks Memorial Award — For
excellence in Medicine and Hematology
Harry Louden Kiracofe
Student Council Keys
Charles Henry Classen
Dwight Norbert Fortier
Franklin Leroy Johnson
Richard Malcolm Susel
Student Council Certificates
James Edward Arnold
Charles Henry Classen
Dwight Norbert Fortier
Franklin Leroy Johnson
Richard Malcolm Susel
Students Elected to Alpha Omega Alpha
Kurt Porter Sligar, President
Stuart Howard Yuspa, Vice-President
Sandra Lee Zucker, Secretary-Treasurer
Arnold Saul Blaustein
William David Ertag
Richard Leroy Flax
George Edward Gallahorn
Stephen Barry Hameroff
William Orville Harrison
Larry Travis Ingle
Harry Louden Kiracofe
Raymond Edgar Knowles, Jr.
Ronald Howard Koenig
Joel Arnold Krackow
Michael Jay Rokoff
Irvin Murray Sopher
Following the award of honors the
students' wives were presented with the
customary Mrs. M.D. citation.
As part of the Precommencement Exer-
cises, Mr. William J. Wiscott, Managing
Editor of the Bulletin, was presented for
a citation by the School of Medicine, the
citation being reproduced herewith.
Dean Stone then presented Mr. Wiscott
with a silver tray inscribed as follows:
Presented to Williaiii J. Wiscott. Man-
aging Editor, Bulletin. School of Medi-
cine, University of Maryland in appre-
ciation of his efforts and thought in he-
half of the School of Medicine. Given
by the Faculty, March 6, 1966.
i
The hooding ceremony then followed
culminating with the taking of the solemn
Oath of Hippocrates administered by Dean
Stone. The principal address was delivered
by the Reverend Donald C. Kerr, Minister.
Roland Park Presbyterian Church. Mem-
bers of the Class of 1966 and their intern-
ships are as follows: ■
Vol. .=<1.
CIdhh of 1966 Begins Procea
sion from DavidKC Hall.
Class of 1966 Internships
Abramowitz, Leslie
Sinai Hospital, Baltimore, Md.
Acker, Diane L. K.
St. Lukes Hospital, New York, N. Y.
Arnold, James E.
University Hospital, Baltimore, Md.
Bard, Richard H.
Cincinnati General Hospital, Cincinnati, Ohio
Baron, Robert B.
Mount Zion Hospital, San Francisco, Calif.
Barrash, Jay M.
Mercy Hospital, Baltimore, Md.
Blaustein, Arnold S.
University of Chicago Clinics, Chicago, III.
Bosley, William R.
Strong Memorial, Rocliester, N. Y.
Braunohler, Walter M.
Monmouth Medical Center, Long Branch,
N.J.
Brotman, Sheldon I.
State U. Kings Co. Med., Brooklyn. N. Y.
Brous, Philip P.
Mary Fletcher Hospital, Burlington, Vt.
Brown, Mark
Royal Victoria Hospital, Montreal. Canada
Brownlow, Wilfred J.
Naval Hospital, Belhesda, Md.
Bruther. William F.
South Baltimore General Hospital, Baltimore,
Md.
Buchness, Michael P.
Public Health Service, Staten Island, N. Y.
Carty, James W., Jr.
Union Memorial Hospital, Baltimore, Md.
Clarke, Dana
Syracuse Upstate Medical Center, Syracuse,
N. Y.
Classen, Charles H.
Union Memorial Hospital, Baltimore, Md.
Cohen, Arthur
Prog IV George Washington, Washington,
D.C.
Cohen, Ora R.
Jackson Memorial, Miami, Fla.
Collins, Hammond C.
New England Center, Boston, Mass.
Cook, David M.
Parkland Memorial, Dallas, Texas
Cost, Francis H., Jr.
Mercy Hospital, Baltimore, Md.
CosTLEiGH, Robert P.
Swedish Hospital, Seattle, Wash.
Crist, Henry S.
Harrishurg Hospital, Harrisburg. Pa.
Dvoskin, Philip B.
Mercy Hospital, Baltimore, Md.
Ellis, Michael A.
Mercy Hospital, Baltimore, Md.
Ertag, William D.
Montefiore Hospital, Ncm- York, N. Y.
Fine, Stuart L.
University Hospitcd, Baltimore. Md.
Flax, Richard L.
University Hospitals, Cleveland. Ohio
Fleming, Gary A.
South Baltimore General Hospital. Baltimore,
Md.
FORTIER, DWIGHT N.
Mercy Hospital, Baltimore, Md.
France, Joseph M., Jr.
Mercy Hospital, Baltimore, Md.
Gallahorn, George E.
Bellevue 3rd 4th Medical, New York, N. Y.
Gattis, Bruce W.
Bernalillo County, Albuquerque, N. M.
Gerber, S. Bruce
Mercy Hospital, Baltimore, Md.
Gersten, Kenneth C.
Public Health Service, Staten Island, N. Y.
Glass, Richard S.
Army Medical Service Hospital, Brooke
General Hospital
Goldberg, Marshall C.
Public Health Service, Boston, Mass.
Golladay, Donald E.. Jr.
Naval Hospital, Oakland, Calif.
GOMBART, AUGUSTIN K.
Harrishurg Hospital, Harrishurg, Pa.
Gordon, Dennis H.
U. Utah Afjfil. Hospital. Salt Lake City, Utah
Gordon, Stephen F.
Sinai Hospital. Baltimore, Md.
Green, John G.
Mercy Hospital, Baltimore, Md.
Grenzer, Louis E.
Mercy Hospital, Baltimore, Md.
Griffin, Dean H.
Maryland General Hospital, Baltimore, Md.
Hameroff, Stephen B.
South Baltimore General Hospital. Baltimore,
Md.
liv
\d. 51, No. 3
ALL MM ASSOCIATIOX SECTION
Haney, Michael J.
GriiJy Mcmoriiil Hospiiiil, Alhinui. Ga.
Hanson, I. Rivers, Jr.
York Hospital, York. Pa.
Harrison, William O.
Naval Hospital. Oakland. Calif.
Hawkins, James M.. Jr.
Memorial, Long Beach
Hill, Thomas M.
York Hospital. York. Pa.
HosicK. Elizabeth C.
Albany Hospital, Albany. N. Y.
Ingle, Larry T.
University of Alberta, Edmonton. Canada
Johnson, Franklin L.
University Hospital, Baltimore, Md.
Kiracofe. H. Louden
University Hospital. Baltimore. Md.
Knowles, Raymond E.. Jr.
Mercy Hospital. Baltimore. Md.
KoENio, Ronald H.
Montefiore Hospital, New York, N. Y.
KosKiNEN, Kenneth R.
Maryland General Hospital. Baltimore. Md.
Krackow. Joel A.
Bellevtie 2nd Medical Division, New York,
N. Y.
Kramer. Lloyd I.
Sinai Hospital, Baltimore, Md.
Leibowitz. Robert E.
Grady Memorial Hospital, Atlanta. Ga.
Long, Elmer C, Jr.
Allentown Hospital, Allentown. Pa.
M.\CHiz, Stephen
Jackson .Memorial Hospital. Miami, Fla.
Mann, John H.
Monmouth Medical Center. Long Branch.
N. J.
Marcus, Joseph B.
Ochsner Fotindation, New Orleans. La.
Marek, William J.
South Baltiitiore General Hospital, Baltimore,
Md.
M\son, William T.
Mercy Hospital. Baltimore, Md.
Mattsson, Carl A.
Thomas D. Dee Memorial. Ogden, Utah
McCaffrey. Jane C.
University Hospital, Baltimore, Md.
Miller, Albert T.
South Baltimore General Hospital, Baltimore,
Md.
Monfried, Allan J.
Sinai Hospital, Baltimore. Md.
Music, Stanley L
University Hospital. Baltimore, Md.
Oldroyd, John J.
Army Medical Service Hospital. Walter Reed
General Hospital
Ominsky, Barry E. L.
Mercy Hospital. Baltimore. Md.
Orfuss, Carl J.
Jackson Memorial. Miami. Fla.
Pass, Carolyn J.
Public Health Service, Baltimore, Md.
Patrick, George S.
St. Agnes, Baltimore, Md.
Plotnick, Gary D.
University Hospital, Baltimore, Md.
Press, Samuel E.
Kaiser Foundation, Stin Francisco
QuiNLAN, James A., Jr.
Mercy Hospital, Baltimore, Md.
Raine, Dudley A., Jr.
Baltiitiore City Hospitals, Baltimore, Md.
Rawlings, Nina C.
Maryland General Hospital, Baltimore, Md.
Reed, Richard H.
South Baltimore General Hospital, Baltimore,
Md.
Rivera-Rivera, Ernesto
University of Puerto Rico, Rio Piedras,
Puerto Rico
Rokoff, Michael J.
Mercy Hospital, Baltimore, Md.
Schwartz, David S.
Union Memorial Hospital, Baltimore, Md.
Serritella, Alfred A.
Presbyterian St. Lukes, Chicago, 111.
Shuger, Richard D.
Mercy Hospital, Baltimore, Md.
Siple, Donald J.
San Francisco Hospital, San Francisco, Calif.
Sligar, Kurt P.
University Hospital, Baltimore, Md.
Sopher, Irvin M.
University Hospital, Baltimore, Md.
Spence, James W.
/// Surg., Boston University, Boston, Mass.
Steers, John E.
York Hospital, York, Pa.
Steinbauer, David J.
South Baltimore General Hospital, Baltimore,
Md.
July. 1966
BULLETIN OF THE SCHOOL OF MEDICINE. UNU'ERSITV OF MARYLAND
Stern, Jack I.
/ & 111 Med., T lifts, Boston, Mass.
Stier, Jeffrey S.
Beth Israel Hospital, NeH- York, N. Y.
Stram. Robert A.
Mary Fletcher Hospital, Burlington, Vt.
SusEL. Richard M.
Public Health Service, Baltimore, Aid.
Swan, Beresford M.
South Baltimore General Hospital, Baltimore,
Md.
Trattler, Henry L.
Jackson Memorial Hospital. Miami, Fla.
Wittmann. Stephen J,
Mercy Hospital, Baltimore, Md.
Young, Robert R.
York Hospital, York, Pa.
YusPA. Stuart H.
University of Pa. Hospital, Philadelphia, Pa.
Zalewski, Andrew A.
State U. Kings Co. Med., Brooklyn, N. Y.
ZiMMERLY. James G.
Army Service Hospital, Walter Reed General
Hospital
ZucKER, Sandra L.
University Hospital, Baltimore. Md.
On June 4, 1966, formal graduation exer-
cises were held at College Park with the
awarding of diplomas. Members of the Class
of 1966 then departed for their internships
following a short vacation.
/■<>/. .V. A'-i. 3
BULLETIN School of Medicine
Universlt// of Manj/diid
\'t)LL'ME ^1 OCTOBER, 1966 NUMBER 4
TABLE OF CONTENTS
ORIGINAL ARTICLES Page
Chloramphenicol Treatment of Pyogenic Meningitis .- - 43
Ilornick. K. /v.. .1/./)., Calhu/hrr. L. R.. M.D.. Ronald. A. R.. M.D., Abdullah. J..
M.B.B.S.. Khan. M.A.. .\i.B.B.S.. M.R.C.. Kahit. I.. M.B.B.S. Hassan. S..
M.B.B.S.. Mcsser. J.. Ph.D., Shaft. M. J.. M.B.B.S.. Zahccr Ud-Din. M.B.B.S..
and Woodward, T. £,, M.D., F.A.C.P.
Toxic Epidermal Necrolysis
Report of a Cose 53
Samuel S. Click. A.B.. M.D.. F.A.A.P. and Engcnc S. Bcrcston. M.D., Sc.
(Med.). F.A.C.P.
BOOK REVIEWS — 58
MEDICAL SCHOOL SECTION
Dean's Letter
Curriculum Revision 1966 .._
Promotions Announced
Foculty Notes
Dr. Marie Andersch Retires
OBITUARIES
John Mason Hundley, Jr., 1891-1965
T. Nelson Carey 1903-1966
Albert E. Goldstein Memorial Fund Organized..
Edgar B. Friedenwald 1879-1966
ALUMNI ASSOCIATION SECTION
President's Letter
Roster of Senior Alumni
Class Notes
INDEXES
Vol. 49, 1964 xxxiii
Vol. 50, 1965 xxxviii
Vol. 51, 1966 xli
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Chloraiiiplieiiicol Treat ineiit of
Pvojieiiic Meningitis*
HORNICK, R. B., M.D., GAUAGER, L. R., M.D., RONALD, A. R., M.D., ABDULLAH, J., M.B.B.S., KHAN,
M.A., M.B.B.S., M.R.C., KHAN, I., M.B.B.S., HASSAN, S., M.B.B.S., MESSER, J., Ph.D., SHAFI, M. J.,
M.B.B.S., ZAHEER, UD-DIN, M.B.B.S., and WOODWARD, T. E., M.D., F.A.C.P.
IN 1954. \\c reported that chloram-
phenicol cfTcctively cured patients with
influenzal, meningococcal, pneumococcal
and other forms of meningitis when given
early in the course of infection. (Parker
ci ill. 1955.) It failed as had other anti-
biotics when given late in illness after
irreversible tissue changes had ensued.
Deaths in seven of 1 11 patients treated
were attributed to treatment delay in the
presence of stupor, coma, and extensive
tissue changes.
Regimes providing multiple anti-bac-
terial drugs have been advocated for
patients with influenzal, meningococcal
and pneumococcal meningitis. (Swartz
et al. 1965.) Other investigators have
used sulfonamides or penicillin solely for
meningococcal infections (Dingle et al.
1941 and Lepper et al. 1952), peni-
cillin alone for pneumococcal meningitis
(Swartz et al. 1965 and Lepper et al.
1951), and chloramphenicol in influenzal
meningitis. (Schoenbach et al. 1952 and
McCrumb et al. 1951.)
Our thesis, expressed a decade ago. is
unchanged since we are not convinced
* From the Department of lledicine and the Institute
of International Medicine. University of Maryland
School of Medicine, the Children's Hospital of the
Fatima Jinnah Medical College, Lahore, and the Ea^t
Medical Service, Mayo Hospital, Lahore, Pakistan.
This study was supported in part by Research Grant
Xo. 11327 entitled. International Center for Jledical
Research and Training from the Office of International
Research. National Institutes of Health of the United
States Public Health Service. Department of Health.
Education and Welfare. Supported in part bv a grant-
in-aid from the Parke Davis Company, Detroit.
that multiple drugs arc necessary for most
cases of meningitis as advocated generally.
Our regimen has consisted solely of
chloramphenicol, in adequate doses, for
treatment of most patients with pyogenic
meningitis. The antibiotic exerts a wide
range of antibacterial action and pene-
trates readily into the cerebrum and
meninges. (Woodward et al. 1958.)
Many therapists agree that chlorampheni-
col is a potent drug for treatment of
meningitis and include it in recommended
multi-antibiotic regimens. (Swartz et al.
1965. Alexander et al. 1953, Smith et al.
1953, Petersdorf et al.) Obviously, if one
antibiotic cures effectively there is no need
for exposure to additional drugs. Cure
cannot be compounded.
Our experience has developed slowly
because of a relatively low incidence of
meningitis on our service; the current
trend to treat febrile patients with various
antibiotics reduces the number of accept-
able cases. This report describes the re-
sults of chloramphenicol therapy in
patients with meningitis caused by Diplo-
cocciis pneumoniae, Neisseria intracel-
liilaris. as well as a few miscellaneous and
unclassified types.
Methods of Stud.v
Selection of Cases: Twenty-eight of 43
patients in the chloramphenicol group
were hospitalized at the University of
Maryland. Baltimore, Maryland, the
October, 1966
43
BULLETIX OF THE SCHOOL OF MEDICINE. UNIJ-ERSIT)- OF MARYLAND
Others at the Mayo, and Sir Ganga Ram
Hospitals, Lahore, West Pakistan.
CHnical manifestations typical of men-
ingitis were present in each case and the
diagnostic clinical and laboratory criteria
previously described were maintained.
(McCrumb el al. 1951.)
For various reasons, beyond our con-
trol, no attempt was made to alternate
treatment using other antibiotics as con-
trols. However, less severely ill patients
encountered early in their disease were
not selected for the chloramphenicol ser-
ies. The cases reported reflect the total
hospital experience for the periods speci-
fied. A patient who had received an anti-
biotic prior to hospitalization was in-
cluded in the series only if the organism
was identified in the blood, spinal fluid
or skin lesion. In most instances, only
chloramphenicol was given; other anti-
biotic exceptions are described in the text.
Therapeutic Regimen: The initial dose
of chloramphenicol for adults was calcu-
lated on the basis of 50 to 75 mgm. per
kilo body weight and similar daily doses.
Children received 75 to 100 mgm. per
kilo as an initial and daily dose. Usually,
chloramphenicol succinate was given
intravenously initially in order to achieve
a prompt high concentration of antibiotic
in the blood and meninges. Capsules were
given orally when possible and occas-
ionally the powdered antibiotic from the
capsule was suspended in saline and ad-
ministered by gastric tube. The gastric
tube was useful also for giving fluids and
nutrients which reduced the need for
intravenous alimentation. A few children
were given Chloromycetin Palmitate by
mouth.
Penicillin regimens provided not less
than 10 million units per day with com-
parable doses for children. The intra-
thecal route was not used.
Therapeutic Results
Summary of Results of 1954 Study
(Parker et al. 1955).
Data from our initial report are re-
viewed briefly with the pertinent data
presented in Table 11.
One of 49 patients with meningoccocal
infections treated solely with chloram-
phenicol died of fulminant meningococ-
cemia and meningitis. Autopsy showed
bilateral confluent adrenal hemorrhages
and culture of the blood, spinal fluid and
adrenal tissues failed to yield N. intra-
cellularis. Three deaths in 35 patients
with Hemophilus influenzae meningitis
were in infants aged less than one year
in whom specific treatment was instituted
on the 8th and 14th days. Three of 17
fatal patients with meningitis due to Diplo-
coccus pneumoniae were aged 2, 51 and
65; they were treated initially on the
fourth, second and fourth days of disease,
respectively. This child died of over-
whelming infection, one adult was an
alcoholic with delirium tremens, and the
oldest patient developed a superimposed
hemolytic staphylococcal infection.
Current Results
Since the initial experience in 1954, 43
patients with purulent meningitis have
been treated with chloramphenicol alone.
Of these, 13 had bacteriologically identi-
fied meningococcal meningitis, 19 pneu-
mococcal meningitis and one caused by
staphylococci. There were 10 patients
(5 in the Pakistan series) with purulent
meningitis in whom no bacterial agent
was isolated from the blood or spinal
fluid; they are classified as undiagnosed.
Pertinent clinical and laboratory data
were given in Table I.
N. intracellularis Meningitis
As shown in Table 1, 13 patients with
meningococcal meningitis were success-
es/. .^2. No. 4
HORXICK ET AL.—CHLORAMPHEXICOL TRF.ATMr.XT (>!■ M liX IXdl'l IS
Table I. Therapeutic Results in 13 Patients with Purulent Meningitis
Treated Solely with Chloramphenicol Baltimore and Pakistan 1959-65)
Xo.
Av. Day
Disease
Kx.
Started
Treat-
ment
Davs
(Av.)
Duration
Fever
after
Rx.
Diseases
Compli-
cations
Xo.
Deaths
Bacterial Typi'
No.
Percent
X. intracellularis
13
2.2
10.0
4.3
1
1
D. pnemiioniae
19
2.7
1-1
5.0
10
6*
1
Hemolytic staphylococcus
1
2
11
3
—
I'nidentitied
10
2.2
10
4
-
3**
2
Totals
43
3
7%
* 2 relapsed; 2 cranial nerve involvement prior to therapy; 2 associated bacterial endocarditis
** Cranial nerve involvement prior to therapy
Table II. General Summary of Results in 154 Patients with Purulent Meningitis
Treated Solely with Chloramphenicol (1950-54; 1959-65)
1950-54
-
1959-65
-
TOTALS
Bacterial Type
No.
Deaths
%
No.
Deaths
%
No.
Deaths
%
X. intracellularis
49
1
2
13
62
1
2
D. pneumoniae
17
3
18
19
1**
5
36
4
11
H. influenzae
35
3
9
35
3
9
Miscellaneous +
5
1
6
Unidentified
5
1*
20
10
2***
20
-
15
3
20
Total
HI
8
7
43
3
7
154
11
7
-|- Includes one case each of Salmonella choleraesius, Listeria monocytogenes, hemolj'tic Staphylococ-
cus, viridans Streptococcus, B hemolytic Streptococcus, and non-hemolytic Streptococcus. All
recovered fully.
* Expired within one hour of hospitalization.
'* Expired within four hours of hospitalization.
*** Expired within 24 and 35 hours of hospitalization.
October. 1966
45
BULLETIN OF THE SCHOOL OF MEDICINE. UNIVERSITY OF MARYLAND
Table III. Summary of Results in 38 Patients with Meningitis
Treated with Chloramphenicol and Other Antibiotics (Baltimore 1959-65)
No.
Mean Day
of Disease
Treatment
Started
Mean Dura-
tion Chlo-
ramphenicol
Treatment
(Days)
Mean
Duration
Fever
after Rx
(Days)
No. with
Associated
Diseases
No. with
Compli-
cations
Deaths
Bacterial Type
No.
Percent
D. pneumoniae
13
1.3
12
8.0
11
2
3
23%
(No Chloramphenicol)*
5
1.8
(14)
3.7
4
1
2
E. coli
4
2.8
6.0
3.0
3
3
Viridans Streptococcus
1
1
22
11
1
1
H. influenzae
7
2.8
16.4
6.4
3
1
Mixed infection**
3
1.3
18
5.5
3
1
Unidentified
5
3.2
11.2
2.8
4
1
Totals
38
9
24%
* Penicillin and other antibiotics except Chloramphenicol
** 1 case Microaerophilic Streptococcus, Herella
1 case Staphylococcus, Diphtheroids, S. Faecalis
1 case Staphylococcus, Pseudomonas (Fatal Case)
fully treated with chloramphenicol. They
made a full recovery. These patients were
treated on an average of 2.2 days after
the onset of illness. Clinical response was
prompt and the temperature reached
normal levels within a little over four
days after instituting treatment. One
patient, a child, developed pyoarthritis
of the knee which responded slowly to
chloramphenicol and supplemental peni-
cillin. The meningococcal infection abated
promptly on chloramphenicol.
H. influenzae Meningitis
In the current series, no additional
patients with H. infiuenzcic meningitis
were treated with chloramphenicol ex-
clusively; seven patients were given
chloramphenicol plus other antibiotics,
usually streptomycin and a sulfonamide
drug. See Table III. All recovered fully;
one developed a subdural collection of
fluid and recovered after aspiration.
D. pneumoniae Meningitis
The current series included an ad-
ditional 19 patients with pneumococcal
meningitis treated solely with chloram-
phenicol. See Tables I and II. These
patients were treated on an average of
the third day of disease and received
treatment for about two weeks. Clinical
response was prompt and the temperature
reached normal levels on an average of
five days after instituting treatment.
Death occurred in one patient, aged 37,
who was treated on the second day of ill-
ness. This patient had an associated pneu-
monia, uremia, and died within ten hours
of hospitalization. One patient, a child.
46
r<./. ^L No. 4
HORXICK FT AL.—CHLORAMPHEXICOL TREATME.XT OF MFS'l.XGITIS
Table IV. Pertinent Clinical Data in 12 Fatal Cases of Pyogenic Meningitis
Treated with Chlorainphenicol and Other Antibiotics
Patient
Age
Bacterial
Cause
Presence
of Coma
Day
Disease
Rx
Started
Dav
Death
Initial
CSP
WIJC
cu/mm
Cause of Death
Anti-
biotic
Rx
P.E.
55
D. pneum.
Stupor
2
3
?
Pyoarthrosis
Bacteremia
Rh. Arthritis
Steroid Rx
Tet.
CHL.
M..1.
52
D. pneum.
Stupor
3
3
3.0
Died <U) hrs. Adni.
Pneumonia
Uremia
Pen.
CHL.
Steroids
E.li.
37
D. pneum.
Yes
2
2
2.8
Died < 10 hrs. Hosp.
CHL.
T.H.
28
D. pneum.
Yes
1
1
3.2
Alcoholism
Recurrence
Osteomyelitis cranium
Pen.
E.P.
59
D. pneum.
• Yes
1
1
25.0
Died <■! hrs.
Hosp. Recurrence
Osteomyelitis cranium
Pen.
K.H.
20
D. pneum.
Yes
3
3
20.0
Died <3 hrs. Hosp.
Pen.
CHL.
.T.S.
67
E. coli
Stupor
3
9
15.0
Skull Fracture
Pneumonia
CHL.
CD.
83
E. coli
Yes
Late
3
.3
Pneumonia
Cerebral Infarction
Pen.
Sm. CHL.
S.G.
61
E. coli
Yes
2
3
32.0
Cirrhosis
Diarrhea
Sm.
I.T.
72
Staphylo-
coccus P.
aeruginosa
Stupor
1
24
1.8
Arteriosclerosis
Mastoiditis
Pen. Can.
Sm. Van.
CHL.
CM.
52
Unidentified
Stupor
2
3
1.6
Alcoholism
Mastoiditis
Osteomyelitis cranium
Pneumonia
CHL.
X.T.
61
Unidentified
Yes
3
4
.3
Alcoholism
Carcinoma
Pharyngeal .\bscess
CHL.
responded only partially to chlorampheni-
col and was given penicillin in supple-
mental meningeal doses. The causative
pneumococcal strain was sensitive to
chloramphenicol and to penicillin. This
lack of complete response was unique in
our experience. The palmitate form of
Chloromycetin was given in the early
October, 1966
47
BULLETIN OF THE SCHOOL OF MEDICLXE. UNII'ERSrrV OF MARYLAND
Stages of infection, supplemented by the
intramuscular administration of Chloro-
mycetin Succinate. Although we expect
that adequate concentrations of chloram-
phenicol were not achieved in the
meninges and cerebrospinal fluid, the
point is unproven since antibiotic assays
were not performed in those patients
treated in Pakistan because of technical
limitations.
Thirteen additional patients with pneu-
mococcal meningitis were treated with
chloramphenicol, penicillin and other
antibiotics. See Table III. These patients
were treated on an average during the
second day of disease; treatment regimens
in cured patients averaged 12 days. Eleven
of these patients had associated illnesses,
three died, and two developed compli-
cations of their meningitis.
Five additional patients were treated
with penicillin and antibiotics other than
chloramphenicol for about 14 days. Four
of these patients had associated illnesses,
two died and one developed a compli-
cation of meningitis. Table IV shows that
three of the fatal cases occurred in 4, 10,
and 10 hours after hospitalization. In
addition, these patients were either stupor-
ous or in coma with disease involving
other organ systems. Two of these fatal
cases had experienced meningitis previ-
ously.
Miscellaneous Types of Meningitis
A patient with hemolytic staphylococ-
cal meningitis first treated on the second
day of disease responded fully to chloram-
phenicol. The clinical response was rapid
and the temperature reached normal levels
in about three days. See Table I.
Three of four patients with E. coli
meningitis died who were treated with
chloramphenicol and other antibiotics.
As shown in Tables III and IV, the three
fatal patients had serious associated
disease and were treated initially on about
the third day of their illness when one
patient was stuporous and two were in
coma. Each of these bacterial strains
were sensitive to the antibiotics ad-
ministered when tested by the disc method.
A patient with meningitis caused by
Streptococcus viridans treated on about
the third day of disease recovered after
chloramphenicol and other antibiotic
treatment.
Mixed Bacterial Meningitis
As shown in Tables III and IV, one of
three patients with mixed bacterial menin-
gitis treated with chloramphenicol and
other antibiotics died. Each of these
patients had serious associated diseases.
A man, aged 72, with mastoiditis and
severe cerebral vascular disease died.
Staphylococci and Pseudomonas aeru-
ginosa were isolated from his purulent
spinal fluid.
Unclassified Types of Meningitis
Ten patients whose meningitis was not
specifically identified were treated solely
with chloramphenicol. They were treated
on an average of the second day of disease
for approximately ten days. The dur-
ation of fever after treatment was insti-
tuted averaged four days. See Tables I
and II. Two of these patients died
(20%). Each of these fatal cases had
serious associated diseases as shown in
Tables I and IV; one was stuporous on
hospitalization and one was in coma.
Five additional patients whose meningi-
tis was not identified bacteriologically re-
covered following treatment with chloram-
phenicol and other antibiotics. See Table
III. The average day that treatment was
instituted was 3.2 and defervescence oc-
curred in 2.8 days.
To/. 51. No 4
HOKXICK /■■/■ .H.—ClllJiRAMrilliXICOI. TRI-.ATM l-XT Ol- MI-IXIXCITIS
Discussion and Summary
Fatality rates in meningococcal menin-
gitis using either sulfonamides or penicillin
are low, not exceeding 59f. (Dingle ci
al. 1941 and Daniels ('/ «/. 1950). Acute
t'ulminant meningococcal infections ac-
count for therapeutic failure in most
instances. Strains of A', intnicclliilaiis re-
sistant to sulfadiazine occasionally occur
(Miller ct al. 1963) and physicians must
be aware of this possibility. Mortality in
patients with pneumococcal meningitis
treated with penicillin varies from 20% to
30% (Swartz et al. 1965 and Lepper
ci al. 1951). Recovery of at least 90%
of infants and children with H. influenzae
meningitis is expected. (Swartz et al.
1965 and Smith et al. 1950).
Our experience with chloramphenicol
in these three types of bacterial meningitis
compares well; fatality rates from men-
ingococcal, pneumococcal and H. influ-
enzae meningitis were 1.5% in 62
patients, 11% in 36 patients, and 8.5%
in 35 patients, respectively. See Table II.
Recovery in patients with meningitis
caused by the three major bacterial agents
treated by conventional therapeutic regi-
mens is relatively slow (Swartz et al.
1965). Clinical improvement manifested
by increased responsiveness occurs on an
average of about two, three and three days
in meningococcic, pneumococcic and H.
influenzae meningitis, whereas the tem-
perature returns to normal levels in about
three, four and four days respectively.
(Swartz et al. 1965).
Chloramphenicol-treated patients re-
sponded equally well and temperatures
abated in four, five and three days in
meningococcic, pneumococcic and H. in-
fluenzae meningitis, respectively. The
incidence of initial stupor and coma was
comparable to that reported in other
series. These results compare favorably
with any other series and there is no ques-
tion regarding the specific curative agent
since no ollwr drui^.s' were used. Usually,
complications of meningitis involving the
cranial nerves or joints were manifest at
the time of initiating specific treatment.
One patient, a child aged one year,
with confirmed pneumococcic meningitis,
failed to respond satisfactorily to chloram-
phenicol treatment. Continuing fever and
a positive spinal fluid culture after 12 days
forced the supplemental administration
of penicillin. Full recovery ensued. This
experience was unique in this series, and
is presumed to have resulted from inade-
quate dosage. Deaths in meningitis are a
sequel to overwhelming infection and to
the excessive, often irreparable, damage
prior to the time of instituting adequate an-
tibiotic treatment. In some patients, par-
ticularly the aged, there are serious under-
lying and associated illnesses which de-
termine outcome. The meningitis is
another burden rather than the primary
difficulty.
Fatality in meningitis caused by several
bacterial species simultaneously is high.
In the current series, one of three such
patients died. All had received multiple
antibiotics. In one reported series, 20 of
534 patients had meningitis caused by
two or more bacterial types (Herweg et
al. 1963) involving H. influenzae, N. in-
Iracellularis, D. pneumoniae, staphylococ-
ci, streptococci, and gram negative bacter-
ia. The over-all fatality rate was 35%. In
another study of nine cases with mixed
meningitis (Carpenter et al. 1962) all
died. Several antibiotics are required for
treatment of patients with meningitis
caused by gram negative bacteria such as
Klebsiella, Pseudomonas aeruginosa, Pro-
teus bacilli. E. coli, Salmonellae, and less
common types which are serious and carry
high fatality rates. (Swartz et al. 1965.)
Chloramphenicol is effective for many of
these types of infection.
October, 1966
49
BULLETIN OF THE SCHOOL OF MEDICIXE. UNILERSLTV OF .VAIO'LAXD
Excluding tuberculosis and the viral
meningoencephalitides, meningococci and
pneumoncocci in adults, and these path-
ogens plus H. influenzae in children, ac-
count for about 70% of all cases of
meningitis. (Swartz et al. 1965.) Thus,
chloramphenicol is effective in over two-
thirds of the common bacterial causes of
meningitis. Like all drugs, it fails when
outdistanced by the irreversible tissue
damage of bacteria. Prompt effective
treatment is mandatory and there is al-
ways need for accurate bacteriologic con-
firmation in meningitis through proper
direct examination and culture of the
spinal fluid. Ideally, each patient should
be appraised individually when all diag-
nostic facilities are available. Under less
ideal circumstances, sound guidelines may
be derived from studying a properly
stained spinal fluid sediment. Prompt ad-
ministration of adequate doses of anti-
biotic will save lives. Even under ideal
circumstances, the specific diagnosis is
occasionally not made. Chloramphenicol
is useful under these obscure circum-
stances as well as in those specific situa-
tions outlined. It is a major therapeutic
agent for purulent meningitis and may
be the sole drug needed in many types.
Similar findings using ampicillin as the
sole antibiotic have been reported by
Mathies et al. This group treated 192
patients with pyogenic meningitis with
results similar to those reported here.
Our data are inadequate to confirm
that fatality rates are higher in pneumo-
coccal meningitis when penicillin and
chloramphenicol are combined (Swartz
et al. 1965) in contrast to the results with
penicillin alone. As shown in Table III.
3 of 13 patients died who were treated
with penicillin and chloramphenicol
(23% ). This latter rate with two or more
chemotherapeutic agents is in excess to
the 1 1 % associated with chloramphenicol
as the sole antibiotic (Table II). In the
group of 20 patients with purulent menin-
gitis, other than pneumococcal types,
which were treated with penicillin,
chloramphenicol and other drugs in some
instances, there were 4 deaths or 20%.
See Table III. Three of 21 patients with
miscellaneous or unclassified forms died,
(14%) who were treated solely with
chloramphenicol (data from Table II).
Although the trend appears to be signifi-
cant the data may be misleading because
patients were not treated on an alternate
basis. The objective was not to compare
the results of single vs. multiple drug
regimens.
The pertinent question is whether one
antibiotic suffices in lieu of combinations.
Is there valid evidence for employing
multiple antibacterial drugs in purulent
meningitis? There are no reliable con-
firmatory data. In sophisticated medical
settings specific confirmation of meningitis
is made in approximately 90% of cases
(Swartz ('/ al. 1965). Specific diagnosis
was made in 83% of 180 cases in the
Baltimore series, in Lahore 5 of 16
patients were not identified bacteri-
ologically. Prompt and maximal treat-
ment produces excellent results. Many
patients contract meningitis in poor socio-
economic settings without the advantage
of such refinements, albeit necessary.
Under these conditions, multiple drug
therapy is awkward as well as expensive.
If a single antibiotic is effective for the
majority of cases of pyogenic meningitis,
therapy is thereby simplified and more
economical. Chloramphenicol is reliable
in its effectiveness and compares favor-
ably with multiple drug regimens.
Chloramphenicol is not a panacea nor
has it solved the serious therapeutic prob-
lem of purulent meningitis. It is effective
as the sole drug in the three major forms
of bacterial meningitis and is therapeu-
50
/lORXICK P.r AL.—CIII.OKAMrilESICOI. TKF.ATM F.XT OF MFMXiAIIS
tically useful in gram negative infections
caused by Salmoneilae, E. coli, P. cierioji-
iiosa Klebsiellac, and Proteus bacilli.
(Swartz el cil. 1965.) Several drugs arc
often required for treatment of these latter
types yet chloramphenicol merits inclu-
sion in such regimens.
Chloramphenicol, in rare instances,
elicits serious hematologic reactions, such
as aplastic anemia, thrombocytopenia and
pancytopenia. (Rosenbach et al. 1960
and McCurdy ct al. 1961.) We have not
observed a fatal or irreversible reaction in
more than 2,500 patients to whom we
have given chloramphenicol for various
acute infectious illnesses. It is our prac-
tice to use chloramphenicol, and all other
antibiotics for that matter, only for spe-
cifically diagnosed acute infections and
for relatively short periods. The risk of
chloramphenicol is rare but real; neither
can the threat of adverse reactions from
other anti-bacterial drugs be ignored.
(Hirsh et al. 1958 and Dowling et al.
1964.) Few, if any, drugs lack toxic pro-
perties. Delay in instituting maximal
effective treatment to patients with puru-
lent meningitis is far more dangerous and
exceeds the threat of a transient or rare
irreversible toxic reaction. No adverse
antibiotic reactions were observed in the
series.
Conclusions
Chloramphenicol effectively cures pa-
tients with menigococcal and pneumococ-
cal meningitis when given as the sole anti-
microbial drug sufficiently early in the
course of infection. All 13 patients with
meningococcal meningitis recovered. One
of 19 patients with meningitis caused by
D. penumoniae died.
Our total experience with chloram-
phenicol in treating 154 patients with
purulent meningitis is: N. intracellularis
62 patients, one death (1.5%); D. pneu-
moniae 36 patients, 4 deaths (\\%); H.
influenzae 35 patients, 3 deaths (8.5%);
unclassified, 15 patients. 3 deaths (20%)
and miscellaneous types, 6 patients, no
deaths. This represents an overall
fatality rate of 7% in 154 patients.
Therapeutic failure in purulent menin-
gitis appears to be dependent upon delay
in instituting treatment before irreversible
tissue changes have occurred. Our data
suggests that a combination of chloram-
phenicol with penicillin in pneumococcal
meningitis is less effective than when
either drug is used alone. The point is
not proven.
In the current study no significant re-
sistance to chloramphenicol was observed
in the micro-organisms encountered. The
practical implications pertaining to the
use of a single antibiotic in purulent
meningitis are discussed.
Acknowledgement
Grateful appreciation is expressed to House
Officers of the Baltimore and Lahore Hospitals
for their assistance in treating the patients re-
ported. Dr. Merrill J. Snyder, Miss Audrey Funk
and Dr. Z. Hussain rendered technical assistance
without which the study would not have been
possible. Thanks are expressed to the Chiefs
of Service of the Maryland General Hospital,
Baltimore, the Lahore General Hospital and
the Military Hospital, Rawalpindi, West Pakis-
tan, for treating several patients according to
the therapeutic plan. Dr. Nijole and Dr. A. C.
Alevizatos graciously assisted in compiling
factual data from the hospital records.
References
1. Parker, R. T.; Snvder, M. J.; Liu, S. J.;
LooPER, J. W., Jr., and Woodward, T. E.:
Therapeutic range of chloramphenicol in puru-
lent meningitis. Aitlibiotic Medicine, l:\92,
1955.
2. Swartz, M. N. and Dodge, P. R.: Bac-
terial meningitis. A review of selected aspects.
New England J. Med.. 272:725, 1965.
3. Dingle, J. H.; Thomas, L., and Morton,
A. R.: Treatment of meningococcic meningitis
and meningococcemia with sulfadiazine.
J. A.M. A., IJ 6:2666, 1941.
4. Lepper, M. H.: Meningococcic meningitis
treatment with large doses of penicillin com-
Octohcr, 106a
51
BULLETIN OF THE SCHOOL OF MEDICIXE. LWIl-ERSITY OF MARVLAXD
pared to treatment with gantrisin. J. Lab and
Clin. Med., 40:S9\, 1952.
5. Lepper. M. H. and Dowling. H. F.:
Treatment of pneumococcic meningitis with
penicillin compared with penicillin plus
aureomycin. Studies including observations on
apparent antagonism between penicillin and
aureomycin. A.M. A. Arch. Int. Med., SS;439,
1951.
6. ScHOENBACH. E. B.; Spencer. H. C, and
MONNIER. J.: Treatment of H. influenzae
meningitis with aureomycin and chlorampheni-
col. Experience in 30 consecutive cases. Ant.
J. Med.. 12:265, 1952.
7. McCrumb. F. R.; Hall, H. E.; Imburg,
J.: Merideth. a. M.: Helmhold. R.: Defillo.
J. B.. and Woodward. T. E.: Treatment of
Hemophilus influenzae meningitis with chloram-
phenicol and other antibiotics. J.A.M.A.,
145:169. 1951.
8. Woodward. T. E. and WISSE^L\N, C. L..
Jr.: Chloromycetin (chloramphenicol). Anti-
biotics Monograph No. 8. Medical Encvclo-
pedia, Inc.. New York, 1958, pp. 24-32.
9. Alexander, H. E.: Guides to optimal
therapy in bacterial meningitis. J. A.M. A.,
152:662. 1953.
10. Smith. M. H. D. and Herring, G. W :
The treatment of acute bacterial meningitis
in infants and children. Posmraduate Medicine
14: 540. 1953.
11. Petersdorf. R. G.: Other bacterial
menineitides. Cecil-Loeb Te.xtbook of Medi-
cine. XI Edition, pp. 211-212, W. B. Saunders
Company. Philadelphia. 1963.
12. McCrumb. F. R.: Hall, H. E.;
Merideth, A. M.; Deane, G. E.; Minor, J. \'.,
and Woodward, T. E. : Chloramphenicol in the
treatment of meningococcal meningitis. Am.
J. Med.. 10:696. 1951.
13. Daniels. W. B.: Cause of death in
meningococcic infection: Analysis of 300 cases.
Am. J. Med..S:46S. 1950.
14. Millar, J. W.; Siess, E. E.: Feldman,
H. A.: Silverman, C: Frank, P.: In vivo and
vitro resistance to sulfadiazine in strains of
neisseria meningitidis. J.A.M.A., 7S6.139, 1963.
15. Smith, M. H. D.: Chloramphenicol in
treatment of Hemophilus influenzal meningitis.
I.A.M.A.. 143:1405. 1950.
16. Herweg, J. C: Middlekamp. J. N., and
Hartman, A. F. : Simultaneous mi.xed bacterial
meningitis in children. J. Pediat, 63:76-9'},
1963.
17. Carpenter, R. and Petersdorf. R. G.:
Clinical spectrum of bacterial meningitis. Am.
J. .Med.. 33:261-215, 1962.
18. RosENB.\CH. L. M.; Gaviles, A. P.;
Mitus, W. J.: Chloramphenicol Toxicity. Re-
versible vacuolization of erythroid cells. New
England J. Med.. 263:724. 1960.
19. McCuRDV. P. R. : Chloramphenicol bone
marrow toxicity. J.A.M.A.. i76.-588. 1961.
20. Hirsh, H. L. and Putman. L. E.: Peni-
cillin. Antibiotics Monograph No. 9. Medical
Encyclopedia. Inc.. New York, 1958, pp. 18-22.
21. Dowling, H. F. and Lepper, M. H.:
Hepatic reactions to tetracycline. J. A.M. A.,
188:235. 1964.
22. Mathies, Jr.. A. W.: Leedom, I. M.;
Thrupp. L. D.; Ivler, D.: Portnoy. B.: and
Wehrle. p. F.: Experience with ampicillin in
bacterial meningitis. Antimicrobial Aaents and
Chemotherapy— 1965. pp. 610-617.
52
Vol. 51, No. 4
Toxic Epidermal Necrolysis
Reporl of a Case*
SAMUEL S. CLICK, A.B., M.D., F.A.A.P. and EUGENE S. BERESTON, M.D., Sc. (Med.), F.A.C.P.
Toxic Epidermal Necrolysis was
first described by Lyell*'^ of Scotland
in 1956. He reported a case which re-
sembled a scalding of the skin, but in
whom the lesions were limited entirely to
the epidermis without any systemic symp-
toms of shock. He coined the term "toxic
epidermal necrolysis." It has also been
referred to as the "scalded skin syn-
drome." In most individuals with this
condition there is a prodrome of lethargy,
malaise, fever, and then an erythematous
skin eruption followed by the appearance
of bullae. Nikolsky's sign was usually
positive.
Report of a Case
A 37 months old Negro male, an only
child, was admitted to University Hospital
on February 23, 1965, with a complaint of
skin eruption and fever. The patient had ap-
peared well until 24 hours prior to admission,
when the mother noted a diffuse eruption with
fever and desquamation of skin around the
ears. The epidermis was found almost im-
mediately to "slide off in sheets." This child
had a past history of inability to talk and could
not chew solid foods. The child was the pro-
duct of a 40-week gestation, with a birthweight
of 5 lbs. 8V2 ounces. Until the time of his
admission, he had refused solid foods and was
given daily Multivitamins and pureed foods
only.
The parents were both living and in good
health. The family history was negative.
Physical Examination. This well developed,
well nourished child was in no acute distress.
Pulse was 90 and regular, respiration 25, tem-
From the Department of Pediatrics and the Di-
ion of Dermatology. Department of Medicine, Uni-
sity of Maryland, School of Medicine.
perature 102°. Conjunctivae, ears and throat
were not injected. A whitish membrane was
present on both tonsils. There was no signifi-
cant cervical adenopathy. The lungs were clear
to percussion and auscultation. The heart rhy-
thm was regular and no murmurs were heard.
Abdomen: On palpation, no organomegaly or
masses were noted. The skin showed a gen-
eralized fine scaling macular eruption.
Nikolsky's sign could be obtained with slight
pressure on any part of the skin surface.
Exfoliation occurred in sheetlike fashion pro-
ducing a "scalded" appearance. (See Fig. 1.)
Laho ralom Data :
Blood sugar 78 HemoElobin 13.2 Gm. %
Blood Urea NitroEen 9
ms. ^'r Hematocrit 37
Combining power 26 WBC 10.500
Chlorides 103 M.Eq.L. Polymorphonuclear Neu-
trophils filamented 49%
Blood Sodium 141
M.Eq.L.
Blood Potassium 4.9,
M.Eq. L. Monocvtes 12%
Serum Albumin 4.3 Gm. % Eosinophils 4%
Serum Globulin 2.7 Gm. % Basophils 5%
Sickle cell preparation —
negative Platelets 816.000
Urinalysis — negative
The following day, blood hematocrit was
36 and sedimentation rate was 15.3. A throat
culture had moderate growths of hemolytic
staph, coagulase positive: light growth of N.
catarrhalis. and also light growth of hemo-
philus influenza. The hemolytic staphylococci,
coagulase positive, was resistant to penicillin
and Vancomycin.
Repeat urinalysis was again negative. Chest
X-ray was normal. A skin biopsy was obtained
with difficulty.
Biopsy Report: Maceration of the upper der-
mis. Slight thickening of the rete with exocy-
tosis and mildly infiltrated. Section not diag-
nostic. (See Fig. 2) (Courtesy Dr. L. Harmon).
Clinical Course: The child was given Methi-
cillin,® 100 mg. intramuscularly, every 8 hours
for 8 days. A persistent low-grade fever was
October, 1966
53
BULLETIN OF THE SCHOOL OF MEDICINE. UNirERSITY OF MARYLAND
present during the hospital admission. By the
time of discharge, all skin lesions were healed
and the throat was clear.
On the day after discharge, the child became
febrile and anoretic. He was very irritable
and was readmitted to the hospital at 8:25
A.M., with a temperature of 103. 2°F (rectal).
He was in acute distress, with a pulse rate of
140, respiration 28 per minute. At this time,
he had nasal congestion and mucous discharge
and congestion of the tonsils with an exudate
on the right tonsil. A grade I soft systolic mur-
mur was heard over the precordium. but no
radiation was noted with change of position.
Healed lesions resulting from the previous
episode of toxic necrolysis were present on
the arms, legs, anterior and posterior trunk. No
pustules were seen. Nikolsky's sign at this time
was negative.
'- 'Jr^.
Laboratory Findings on Second Admission:
neg-
Hemoelobin 12.2 Gm.
per cent
Hematocrit 36.5
Blood Leucocytes 14,400
Throat culture on March 12, 1965 had hem-
olytic staphlycocci, coagulase positive and a
moderate growth of alpha streptococci.
Antistreptolysin titre on March 16, 1965
was less than 55 todd units.
VRDL (Venereal Disease Reagen Level)
negative.
On March 24, 1965 Blood hemoglobin was
12.5 mg. per cu. mm.
On March 24, 1965 Blood hematocrit was 38.
A collagen disease was suspected and fol-
lowing tests to rule this out were done:
Sedimentation rate 13
Lupus Erythematosus Prep negative
Blood Leucocytes 8,600
Antistreptolysin ls of the im-
portant legal acts which were basic in the
evolution of the university; and also de-
scriptions of the various institutions which
were combined to form the University of
Maryland. There are 215 text pages, and the
appendices occupy 80 pages. There is an
adequate combined index of subjects and
October. 1966
59
BULLETIN OF THE SCHOOL OF MEDICINE. UNII'ERSITV OF MAKYLAND
personal names. There are 3 1 unnumbered
pages of illustrations placed together near
the middle of the text. The binding is
attractive and the text type is clear.
The author's informal style facilitates easy
reading so that the reader becomes ab-
sorbed in the narrative. For her fresh view-
point, and for the literary progeny born of
the painstaking travail of extensive personal
research, this reader is deeply grateful to the
author; and it is his belief that she, a most
loyal alumna of the University of Maryland
School of Medicine, has performed a real
service for her Alma Mater and for the
entire university. She has accomplished
her "triplet" purpose admirably. The book
is warmly recommended to all interested
in the University of Maryland.
John E. Savage. M.D.
Ferment in Medicine. A Study of the Essence
of Medical Practice and of its New
Dilemmas by Richard M. Magraw,
M.D., with collaboration of Daniel B.
Magraw, M.B.A., 272 pp., W. B.
Saunders Co., Philadelphia, 1966.
Professor Richard Magraw, former
family practitioner, long since a consultant
in psychosomatic medicine at the University
of Minnesota Hospitals, has written an ex-
cellent book. In brief, his book represents
the lecture material, background informa-
tion, seminar topics, and wide range of
charts and references which he has found
useful in the instruction of senior medical
students during their six months in the Com-
prehensive Clinic at Minnesota. Lest the
potential reader fear that the book is simply
a pedantic outline, he need fear not. Draw-
ing on a remarkable variety of quotations
from physicians, social scientists, philoso-
phers, administrators, and literary greats
among others. Dr. Magraw, interspersing
his own diversified experience, has forcefully
portrayed the social and professional re-
sponsibilities of the doctor and several of
the major problems for medicine as a force
in society.
The first section of the book analyzes the
doctor-patient relationship as a social con-
tract, stressing the impact of psychological
forces on both members of the contract.
The obvious limitations produced in the
physician by a disease-oriented viewpoint
compared to a patient-oriented viewpoint
are well described. The sense of frustration
felt by many physicians, now in late-middle
age, produced by the relative decrease in
importance of the individual doctors in the
delivery of care is also emphasized.
For readers with a strong interest in the
political role and position of medicine, the
latter half of the book will be more exciting.
There the author, rather dispassionately,
analyzes some of the critical forces which
are now and will in the future impact heavily
on medicine and medical care. Important
topics include doctor-hospital relationships,
the research establishment, medical speciali-
zation, the growth of the health professions
as a whole, third party funding, automation
in medicine, and emerging patterns of
medical care and practice.
The main theme of this book is, in my
view, very critical but frequently overlooked
in the academic setting (and, unfortunately,
among practitioners as well). Dr. Magraw
stresses, with good justification, the need for
comprehensive medical care for all patients,
rich or poor, urban or rural, medically
sophisticated or not. There must be, in his
view, some single physician or, less desir-
ably, single system to assure each patient
continuity of care emphasizing just those
things lost sight of in the typical inpatient-
oriented training of the great majority of
American physicians. In an era of chronic
diseases, more concern, in his view, about
prevention, early diagnosis, rehabilitation,
and health maintenance will be mandatory.
In summary. Dr. Magraw has written a
book on the social place of medicine and
medical care which, I hope, large numbers of
students, faculty, practitioners, and medical
administrators will consider essential read-
ing.
Mitchell J. Rosenholtz, M.D.
60
Vol. 51. No. 4
MEDICAL SCHOOL SECTION
'Dean's
LETTER
Dear Members of the Alumni. Students and Friends of the Medical
School:
After careful study and faculty action as a result of the medical
faculty workshop at College Park on June 13th-16th of this year,
the Medical School will change its curriculum by a program of inte-
grated teaching in both the basic science and clinical years. This
means that teaching will not be done under departmental jurisdiction,
but under the direction of a faculty committee using representative
teachers from whatever department is deemed capable of conducting
the teaching of the specific subject. The program will start in the
basic science subjects in the fall of 1966 and hopefully progress to
other years as the entering class of 1966 completes each phase of its
four years study of medicine.
This method of teaching will provide a better integration and
coordination of subject matter with more thorough coverage of
principles involved and will prevent needless duplication. The
student will be expected to learn as a graduate student and will have
more free time to devote to areas of his or her special interest.
Sincerely,
Wm. S. Stone, M.D.
Dean
October. 1966
Ciirriculuiii Revision 1966
Through a period from 1952-1954. ex-
tensive curriculum changes were introduced
in conformity with new concepts of teach-
ing in both the clinical and basic science
years, these changes being the result of im-
provements in departmental staffing and the
greater availability of full-time teachers.
This curriculum continued in force until
1963, when the faculty assembled for a
week-long seminar devoted to medical edu-
cation held at the Airlie House near
Warrenton, Virginia. On this occasion, re-
views of teaching methodology and the
philosophies of modern medical education
were studied in some depth and at the
same time compared with existing curricula
and techniques. From these deliberations
emerged a new and revised concept of an
on-going curriculum study by a permanent
committee devoting its attentions exclusively
to this academic problem. This committee
began work in November, 1963. By June
of 1966. its deliberations and conclusions
had reached a point where a second faculty
conference on problems of medical edu-
cation was deemed advisable.
Accordingly, a second conference on
medical education was held at the Center for
Adult Education in College Park during
the week of June 13. 1966. At this time
the curriculum committee unveiled the first
fruits of its almost two-year study effort.
Preliminary proposals for broad curriculum
changes to be introduced gradually were
presented. In general, these involved the
gradual abandonment of the linear-year-
course system with related didactic lectures,
reverting the philosophy of medical edu-
cation to that of a conceptual pyramid
composed of segments, each of these being
the result of the interaction of numerous
disciplines and specialties, each subject re-
lating to a concept of basic knowledge and
its clinical application, the student being
guided in the acquisition of detail which
he would acquire by himself.
Citrricuhnn change for First Year
adopted. At a meeting of the faculty on
July 7, 1966, the curriculum committee
presented in some detail a revised curriculum
for the first year. This was adopted and
will be instituted with the class of 1970. In
its general form, the curriculum is quite
simple and is composed of four major
divisions.
Anatomy. In this revised concept, cell
morphology, ultrastructure, cell function and
genetics will be combined with conventional
embryology and histology. The total
scheduled time for gross anatomy has been
reduced by 25%. Students will dissect an
infant and only specific areas of an adulf
cadaver. The routine complete dissection of
an adult cadaver has been abandoned. This
conjoined curriculum will be closely as-
sociated with the second major unit known
as the Biophysics, Biochemistry, Physiology,
and Pharmacology curriculum (B.B.P.P.).
B.B.P.P. Citrriciditm. This portion of the
course will concern itself with tissue
chemistry, cell chemistry, membrane phe-
nomena, biophysical states, various meta-
bolic systems, the physiology of normal
organ function and the inter-relationship of
organ systems. There will be a basic study
of the effect of drugs on cells, tissue and
organ function.
Neurological Sciences. Paralleling the
work of the curriculum committee, the
neurological sciences group composed of
representatives of Neurology, Neurosurgery,
Neuropathology, Anatomy, Physiology,
Pharmacology, Anesthesiology, and Electro-
encephalography held numerous meetings to
develop a neurologic curriculum designed
I'ol. .-I. X.
MEDICAI. SCHOOL SECTION
to create lor the stiidenl a useful foundation
in the hasic sciences and a continuing de-
\elopment of conceptual knowledge in the
clinical neurologic sciences. The deliber-
ation of the committee resulted in a neuro-
logical science curriculum which was actively
in effect during the year 1965-1966 and
which will he continued with improvements
as part of the new adopted revised cur-
riculum called "Neurological Science I" is
as follows:
The student is introduced to Neurological
Science by way of formal courses in Neuro-
anatomy and Neurophysiology which have
been carefully integrated and which are
taught in a parallel fashion with numerous
mutual conferences between responsible in-
structors. To these, some enrichment courses
are appended from time to time with plans
for clinical presentations in Neurology,
Neurosurgery, Neuropharmacology, Anes-
thesiology, and Neuropathology. There is
no content curriculum to these enrichment
subjects as they are used to give the student
a growing purposeful insight into the re-
lationship of the basic science activity to
his ultimate practice of medicine and neu-
rology. The "core" curriculum is reserved
for the major field.
Curriculum Study to Continue
Already the curriculum committee has
turned its attention to the development of
the second year curriculum. The neurologic
science group is actively engaged in develop-
ing its second stage project to be called
"Neuro'ogical Science II." As these inno-
vations develop, they will be presented in
these pages.
Future
It is hoped that continuing study and
curriculum revision will result in a more
closely knit interdepartmental approach to
the problems of the medical student en-
abling him to use the techniques and knowl-
edge of basic science toward the better
understanding and more rational scientific
approach to the clinical management of
human illness.
PROiVIOTIONS ANNOUNCED
Dr. William S. Stone, dean of the Uni-
versity of Maryland School of Medicine,
has announced the promotion of six faculty
members. Dr. William J. Adelman, Jr., Dr.
Ra>mond A. Sjodin, and Dr. Matthew Tay-
back have been promoted to full professor,
and Dr. Safuh Attar, Dr. Charles G.
Crispcns, Jr., and Dr. Richard B. Hornick
have been promoted to associate professor.
Dr. Adelman, named professor of physi-
ology, has won international recognition for
his basic research on nerve cells. He came
to the University of Maryland in 1962 after
three years at the National Institutes of
Health working in the biophysics laboratory
of Dr. Kenneth Cole. He had previously
been a faculty member of the University of
Buffalo School of Medicine for three years.
An alumnus of Fordham University, he
earned an M.S. degree at the University of
Vermont and a Ph.D. at the University of
Rochester.
Dr. Adelman is a member of the
Corporation of the Marine Biological
Laboratory at Woods Hole, Massachusetts,
where he conducts physiological research
during the summer months. He has also
worked in England in the Physiological
Laboratory of the University of Cambridge
and at the Marine Biological Association in
Plymouth.
Dr. Adelman was recently elected a fel-
low of the American Association for the
Advancement of Science and is a member
of the American Physiological Society, the
Biophysical Society, Sigma Xi, the Society
of General Physiologists, and the Society
for Experimental Biology and Medicine.
Dr. Sjodin, named professor of biophysics,
joined the then newly established depart-
ment of biophysics in 1960 and has made
many important contributions to its de-
velopment. He has initiated new courses,
helped to plan the graduate program and
research activities, and cooperated with
faculty members of other departments in
teaching neurological science to medical
students.
October, 1966
BULLETIN OF THE SCHOOL OF MEDJCLXE. U.\irEr<Srf)' OF MARVLAXD
Dr. Sjodin's research programs are con-
cerned with the discovery of basic
mechanisms underlying the electrical ac-
tivity of nerve and muscle cells. This re-
search combines the methods of electrical
measurement with radioactive tracer tech-
niques to study ion movements across the
cell membrane. He is the author of numer-
ous major scientific papers relating to this
work. In addition, he has performed work
in collaboration with Dr. Adelman and Dr.
Lorin J. Mullins. chairman of the depart-
ment of biophysics.
Dr. Sjodin earned a B.S. degree at the
California Institute of Technology and a
Ph.D. degree at the University of Cali-
fornia at Berkeley. He did postdoctoral
work at Purdue University, and as a fellow
of the National Institutes of Health, he
studied at the University of London and
the University of Uppsala in Sweden. He
is a member of the American Physiological
Society, the Biophysical Society, and the
Society of General Physiologists and is a
fellow of the American Association for the
Advancement of Science. He has been a
participant in international scientific meet-
ings at Buenos Aires. Moscow, Stockholm,
and Tokyo.
A member of the Corporation of the
Marine Biological Laboratory at Woods
Hole, Massachusetts, Dr. Sjodin is conduct-
ing physiological research there during the
summer months.
Dr. Tayback, named professor of bio-
statistics, is Deputy Commissioner of Health
for the City of Baltimore. He has been with
the Baltimore City Health Department since
1949 and was previously a senior statistician
for the New York State Health Department.
He has been a member of the Maryland
medical school faculty since 1952 and also
lectures on biostatistics and public health
administration at Hopkins.
A graduate of Harvard, Dr. Tayback re-
ceived an M.A. degree from Columbia and
an Sc.D. degree from the Hopkins School
of Hygiene and Public Health. He is a
fellow of the American Public Health As-
sociation. Results of his research, relating
to epidemiology, public health administra-
tion, program planning and evaluation, and
population statistics, have been published
in a number of professional journals.
Dr. Attar, named associate professor of
thoracic and cardiovascular surgery, is a
native of Lebanon. He received his medical
degree with honors from the American Uni-
versity in Beirut, where he interned and
trained in surgery and was chief resident
in 1955. After spending a year as fellow
in cardiovascular surgery with Dr. Michael
E. DeBakey at Baylor University in Houston,
he came to University Hospital in Baltimore
to complete his training in thoracic surgery
from 1957 to 1959. He is director of the
thoracic surgery clinic at the University
Hospital, attending thoracic surgeon at
Mercy Hospital, and consultant to Mt.
Wilson State Hospital.
In addition to his clinical responsibilities,
Dr. Attar is engaged in the study of coagu-
lation changes in human shock and in
evaluating the use of hyperbaric oxygenation
in the treatment of shock. He is the author
of more than 65 papers on heart and vascu-
lar surgery and related physiology, and has
contributed to six books. He is a diplomate
of the American Board of Surgery and the
American Board of Thoracic Surgery and
a member of 17 medical and professional
organizations.
Dr. Crispens, named associate professor
of anatomy, has made a number of interest-
ing discoveries relating to a virus found in
association with cancers in mice.
Winner of the Lederle Medical Faculty
Award for 1964. Dr. Crispens teaches
medical genetics at the medical school,
where he has been a faculty member for the
past six years. He came to Maryland after
a year as postdoctoral fellow at Jackson
Laboratory. Bar Harbor. Maine. He holds
a B.S. degree from Pennsylvania State Uni-
versity, an M.S. degree from Ohio State
University, and a Ph.D. from Washington
State University. Besides publishing many
articles dealing wtih his study of cancer in
birds and mice. Dr. Crispens is also the
rol. 51, A",
MEIUCAL SCHOOL SECTIOX
author ot a reference book on North
Americun game birds.
Dr. Hornick, named associate professor
of medicine, has been director of the di-
vision of infectious diseases since July 1963.
Long term clinical research with prisoner
volunteers at the Maryland House of Cor-
rection, conducted under his direction, has
resulted in major advances in the control
and understanding of several infectious dis-
eases, including typhoid fever and Asian tlu.
A native of Johnstown. Pennsylvania, Dr.
Hornick received A.B. and M.D. degrees
from The Johns Hopkins University. He
interned and served a year of residency at
The Johns Hopkins Hospital before a two-
year assignment at the Walter Reed Medical
Unit in Fort Detrick, Maryland. He joined
the Maryland Medical School faculty in
1959.
Dr. Hornick is a diplomate of the
American Board of Internal Medicine and
a member of a number of professional
societies including the American College of
Physicians, the American Society for Micro-
biology, the American College of Clinical
Pharmacology and Chemotherapy, arid the
Infectious Disease Society of America. He
received the Alexander K. Barton Award
from The Johns Hopkins University in 1951
and the University of Maryland Outstand-
ing Teaching Award in 1964.
Department of Anatomy
Dr. Theodore F. Leveque, Professor of
Anatomy, recently attended the Fourth Inter-
national Symposium on Neurosecretion, held
in Strasbourg, France, July 25-27, 1966.
Attendance at the meeting was by invitation
only and included some 150 scientists repre-
senting 13 countries. Dr. Leveque, an inter-
nationally recognized authority in the field
of neurosecretion, was an active participant
in the open discussions of the symposium.
Sessions were conducted in the newly con-
structed Institut de Physiologie Generale
de la Faculte des Sciences, Universite de
Strasbourg.
On his sabbatical leave, last year, Dr.
Leveque and his family traveled to Stras-
bourg where he expanded his studies on the
glandular periventricular formations in the
hypothalamus of the rat and the mouse.
Dr. Gladys E. Wadsworth, Assistant Pro-
fessor, worked as a research fellow at High-
land View Hospital in Cleveland, Ohio, from
April 18 to July 18, 1966. Dr. Wadsworth,
having broad training in physical therapy
and anatomy, participated in the Hand
Kinesiology Study that is being conducted
in Cleveland by the Ampersand Research
Group for Medical Engineering. In the
course of her work. Dr. Wadsworth used
electromyographic techniques in her studies
of muscles that move the fingers and the
electrogoniometer — an instrument especially
designed for the project — to study angular
displacements of interphalangeal and meta-
carpophalangeal joints during the recording
of hand and forearm muscular activity. Dr.
Wadsworth plans to apply some of the newer
electromyographic techniques in her studies
of kinesiology at the University of Mary-
land.
Department of Medicine
Dr. Jerome K. Merlis, Chief of the
Electroencephalographic Laboratory at the
School of Medicine, is a consulting editor of
the Journal of Electroencephalography and
Clinical Neurophysiology. The journal,
founded in 1947, is the official organ of the
International Federation of Societies for
Electroencephalography and Clinical Neuro-
physiology.
October, 1966
Dr. Marie Andersch
Retires
Members of the faculty of the School
of Medicine, members of the staff of the
University Hospital and friends recently
honored Dr. Marie Andersch at an informal
reception at the University Hospital on the
occasion of her retirement. Dr. Andersch
was also honored by the Department of
Medicine at a formal dinner attended by
many members of that department. Dr.
Andersch, a member of the faculty of the
school for 23 years and Chief of the Bio-
chemistry Section of the Clinical Laboratory,
retires with the rank of Associate Professor
of Medicine in Biochemistry. She was first
appointed in 1943, coming to the University
from a position as a Research Associate in
the Department of Pathology at the Uni-
versity of Pittsburgh. A native of Illinois,
she received her Baccalaureate degree in
1926, from the University of Illinois. For
the next four years, she worked in the
laboratories of the Michael Reese Hospital
in Chicago. In 1933, she received the Doctor
of Philosophy degree in Biochemistry at the
University of Iowa. For the next year. Dr.
Andersch remained at the University as a
Research Assistant, leaving in 1934, to ac-
cept a position of Associate Professor of Bio-
chemistry of the Women's Medical College
in Philadelphia. She accepted the Pittsburgh
appointment two years before coming to
the University of Maryland.
Dr. Andersch's career at the School of
Medicine and the Hospital is marked by a
number of achievements. Not only did she
continue to maintain a high standard of ex-
cellence in the routine chemistry of the Uni-
versity Hospital, but found time to develop
new techniques and to publish more than
25 contributions to the medical biochemical
literature.
In association with the late Dr. Milton
S. Sachs. Dr. Andersch contributed to the
development of the Clinical Laboratory and
extensively to the curriculum of the Di-
vision of Clinical Pathology. She was instru-
mental in developing plans for a School of
Laboratory Science and Technology.
An expert in the field of clinical bio-
chemistry, Dr. Andersch was frequently
sought as a consultant by nearly all of the
hospitals and institutes in the City of Balti-
more and the State of Maryland. Her re-
tirement thus culminates a long career in
the service of medicine: a distinguished
scientific career in biochemistry coupled with
a high sense of devotion: a consistency of
excellence and a fine personality.
'ol. ."■!. A'o. 4
Sof)n fflasion i&untilci', llr.
ISOl = 1005
John iMason Hundley, Jr. died at his home
on December 8. 1965. after a short, acute
illness. Known to his friends as "Jack" and
to his former residents as "Chief" or more
alTectionately as "Docus," Dr. Hundley will
he remembered for his many accomplish-
ments as Professor and Head of the De-
partment of Gynecology at the University
of Maryland School of Medicine and the
University Hospital. His many publications
reflect his particular interest in the diag-
nosis and treatment of pelvic malignancy,
female urology, and gynecologic pathology.
Born in Baltimore on July 8. 1891, Dr.
Hundley received his early education at
Boys" Latin School. After receiving his
.A.B. and M.A. degrees at St. John's College
in .Annapolis. Maryland, he entered the
Johns Hopkins University School of Medi-
cine and was awarded his M.D. degree from
that institution in 1916.
His postgraduate training began with in-
ternship and assistant residency at the Union
Protestant Infirmary, now the Union
Memorial Hospital. Further training was
interrupted by service in the U. S. Army
overseas as a 1st Lieutenant in the Medical
Corps from July 5. 1918, to May 16, 1919.
He returned to Baltimore in 1919 to con-
tinue his residency training at the University
Hospital serving as Chief Resident in 1921
under his father, the late Dr. J. Mason
Hundley. Sr.. then Professor of Gynecology.
In 1930-31 Dr. Hundley studied abroad
and brought back to the University the
teaching of Professor Robert Meyer of
Berlin and Professor Robert Schroeder of
the University of Kiel. His interest in path-
ology, phvsiology, and the then infant disci-
pline of endocrinology was kindled by his ac-
tivities in Germany and stimulated the de-
velopment of clinical research of the physio-
logic effects of pregnancy on the uterus and
the relationship of ovarian hormones to
ureteral peristalsis.
In 1935 Dr. Hundley was appointed Pro-
fessor of Gynecology and Head of the De-
partment at the University of Maryland
School of Medicine. In this capacity he
enlarged and improved the residency of
female urology and established a female
urologic clinic as a memorial to his father.
He had an avid interest in cancer and with
the late Dr. Grant Ward developed a De-
partment of Oncology, pioneering in the
establishment of improved methods of
radium application in the treatment of pelvic
malignancy. He was active in the American
Cancer Society and served as President of
the Maryland Division in 1941. Under the
aegis of this society, he waged a never end-
ing campaign towards the early diagnosis
of malignancy, emphasizing the importance
of regular, periodic examinations, and the
inclusion of an adequate pelvic evaluation
as a part of any routine examination.
Dr. Hundley was very proud of his father,
also an illustrious gynecologist. In addition
to the establishment of the cystoscopic clinic
at the University Hospital, he endowed an
operating room at the Hospital for the
Women of Maryland in honor of his father
and in 1961 established the "J. Mason
Hundley, M.D., Annual Lecture in Gyne-
cology" at the Medical and Chirurgical
Faculty of the State of Maryland.
Dr. Hundley was a member of many
organizations including the American Gyne-
cologic Society, the American Association
of Obstetricians and Gynecologists, the
American Urologic Association, and the
American College of Surgeons as well as the
Baltimore City Medical Society and the
Medical and Chirurgical Faculty of the State
of Maryland.
Dr. Hundley loved to entertain and used
his home to delight his friends with frequent
evenings of delicious food, music, and con-
geniality. He was a raconteur par ex-
Octobcr. 1966
W. i^clson Carcp
1003 = 1966
I'ol. ?1. Xo. 4
Thomas Nelson Carey was a clinician
who cared for patients and who practiced
medicine to the absolute satisfaction of re-
ferring physicians. The pace which he fol-
lowed relentlessly in spite of personal health
handicaps was a source of concern and
inspiration to his friends. Devotion to the
patient's welfare set an example which in-
spired many students and house officers to
perform up to their highest capabilities; they
were rewarded through their rich clinical
experiences with him. Nelson died on March
11, 1966, after brief hospitalization at the
Mercy Hospital.
A native Baltimorean, Nelson was the son
of Thomas and Grace Carey, who lived at
422 Kenneth Square in Govans. Born on
December 15, 1903. his early childhood
was spent in Baltimore: he attended public
schools graduating from Loyola High School
in 1919. He was awarded a Baccalaureate
Degree from Loyola College in 1923 and
his Degree in Medicine from the University
of Maryland School of Medicine in 1927.
While in medical school. Nelson was
awarded the Hitchcock and Randolph
Winslow Scholarship in recognition of aca-
demic achievement which culminated in
his selection for the Faculty Gold Medal
emblematic of highest class honors. The
financial costs of his education were earned
in various ways including working as a
soda clerk in MacGillivray's Pharmacy
where he worked circles around good em-
ployees. After graduation Nelson gained
the reputation for accuracy and efficiency
as an intern and medical resident at the
Mercy Hospital. Long, tiring hours were
taken in stride and patient workups were
thorough. Always a scholar, he terminated
his formal postgraduate education in 1930
with a year of fellowship at the Johns
Hopkins Hospital working on problems of
allergy under Dr. Leslie Gay.
Nelson opened his office for medical prac-
tice in 1931 at 1014 St. Paul Street where
patients consulted him for 35 years. Quick
in decision he had unusual ability as a diag-
nostician and thrived on difficult clinical
problems. Knack for sifting the routine
from the difficult and promptly reaching an
accurate conclusion spared his patients from
long hospitalizations. Surgeons eagerly gave
service because of his astute judgment.
Frequently, he correctly advised surgical
intervention in spite of conflicting x-ray or
laboratory evidence which he regarded only
as confirmatory aids. Final judgment was
predicated on careful analysis of the history
and bedside manifestations. Always there
was anecdotal phrase circulating the hospital
staff highlighting an experience with him
in the sickroom. On one occasion when an
ill recalcitrant patient, hospitalized for
several weeks, complained, "You can't have
any more tests to do," Nelson retorted, "Yes,
there is one more, your post mortem ex-
amination."
Nelson continuously carried a heavy
hospital and office practice and in spite of
the responsibility and concern which diffi-
cult problems provoke, he gave confidence
and was constantly sensitive to patient's
needs. He delighted in sifting out clinical
puzzles for the referring physician, an attri-
bute which was largely responsible for his
large consulting practice. Patient service was
rendered promptly during weekdays, nights
or Sundays and similar standards were ex-
pected of those under him. Nelson was
constantly seen walking the hospital corri-
dors with stacks of medical records. Re-
ports to doctors were dispatched promptly
and were remarkable for their clarity,
October, 1966
^ULLETIX OF THE SCHOOL OF MEDICISE. UMrERSITV OF MARYLAND
brevity, diagnostic accuracy, and wisdom of
his therapeutic regimen. Physicians con-
sulted him for personal medical care, a
recognized accolade of ability and sincerity
Baltimore has had a rich tradition of
clinicians such as Hamman, Wilson and
Pincoffs. Nelson Carey was a member of
this class of men.
Medical students had Nelson Carey as
their personal physician for many years. For
more than two decades his private medical
service was a major teaching unit for house
officers. Patient referrals came from phy-
sicians throughout Baltimore, Maryland and
neighboring states providing a practice
which cut across all segments of clinical
medicine. This truly teaching service pro-
vided a rich experience for interns and resi-
dents; those who occasionally shirked duty
were sharply rebuked. House officers en-
joyed serving him.
Nelson read extensively and kept abreast
of pertinent advances in the medical litera-
ture. A patient with Streptohacilhis monilo-
formis infection was correctly diagnosed by
him at the Mercy Hospital after casual con-
versation with a resident who related the
manifestations of fever, arthritis, and rash.
His patients were generously made available
to associates for clinical study and he per-
sonally reported interesting case studies. One
of his patients is the first reported instance
of Coxsackie Virus myocarditis in an adult.
Nelson's knowledge embraced various
medical subspecialties, particularly infectious
diseases, metabolic, and allergic disorders.
With his fundamental knowledge of the
natural patterns of disease, he had the ad-
ditional keen sense of detecting key changes
at the bedside. These provided leads for
fruitful investigation which he unselfishly
shared with full-time colleagues. In this way
his personal suggestions led to the use of
Flexin in treatment of gout. Nelson had an
agile mind which he used well.
The School of Medicine and Hospital are
in his perennial debt for dedicated service.
Early in his career he carried a heavy teach-
ing schedule and with the exodus of large
segments of the faculty in World War II,
he taxed himself unsparingly. Daily ward
teaching and the conduct of a huge consult-
ing practice served as essential programs for
instruction of young physicians. Students
packed Gordon Wilson Hall from 1942-46
to hear his presentations at the weekly
clinical pathological conference; they re-
ferred to him as "T.N.T." From 1948 to
1949, Nelson directed the Department of
Medicine in the capacity of Acting Head.
His interest in career advancement of
medical students and house staff is shown
by his many letters endorsing them for
positions in other teaching hospitals. These
letters described the candidate accurately;
they were crisp, honest, and without undue
flare.
Friends knew of his sharp wit and his
love for quoting the classic literature. He
was an avid reader of prose, poetry, and
modern satire. Marquand was a special
favorite. La Tosca and Rigoletto his favorite
operas, and Mozart his favorite composer.
The shore provided necessary respite from
routine during part of the summer and in
later years Nelson and Mary relaxed in
New York or Boston taking in the shows
and enjoying other cultural outlets. A trip
to Ireland in 1962 gave them special
pleasure.
On the evening of January 29. 1963,
Nelson's medical associates joined with his
loving family to pay homage on the oc-
casion of a testimonial dinner when he re-
ceived the traditional Maryland chair and
plaque appropriately inscribed: "T. Nelson
Carey, M.D., F.A.C.P.. with fond apprecia-
tion for his many years of devoted service
as a talented, tireless clinician and as an in-
spirinf; teaclier."
A University teaching hospital can ill-
afford to reduce such a brilliant internist
from its ranks, a true clinician, reliable
friend, capable teacher and one who so
effectively related the practice of specialty
medicine to a University teaching center.
Nelson's loss is more apparent with time:
missed because of the example which he set
for others, for his high ethical standards and
for his dedication to good medicine.
Vol. 51. Xo. 4
MEDICAL SCIIOOI. SllCTlOX
Nelson held membership in the American
College of Physicians, the American Medical
Association, the Baltimore City Medical
Society, the Maryland Medical and Chirurgi-
cal Faculty and he was a Diplomate of the
American Board of Internal Medicine. In
1966, prior to his death, the Maryland
Medical Alumni Association appropriately
awarded him its Gold Medal and Honor
Award. This is the highest accolade of the
Association for outstanding contributions
to medicine and distinguished sers'ice to man-
kind.
In 1924, the following was said of Thomas
Nelson Carey in a letter supporting his
application to the medical school, "'He Is
the type of young man we want in the
medical profession at the present day." This
prophecy was richly fulfilled.
The staff members of the University and
Mercy Hospitals and the Sisters of Mercy
tender their sympathy to Mrs. Mary C.
Carey and to his children. Mrs. Margaret C.
Maher; Mr. Thomas N. Carey, Jr.. and
Miss Mary Frances Carey who survive him.
Throughout his adult life this warm family
circle provided him the solace and strength
so necessary to support his intense and dedi-
cated way of life. Heartfelt gratitude is ex-
pressed to his gracious wife, Mary, by those
physicians who were enriched through their
pleasant associations with him.
Theodore E. WooDw.'kRD. M.D.
cellence and often held his fellow members
of the Splint Club entranced by his anec-
dotes.
In 1955 Dr. Hundley was made Emeritus
Professor and in 1958 he retired from prac-
tice. He represented an era in the develop-
ment of the University of Maryland marked
by conservatism, scrupulous intellectual
honesty, and a dedication to provide the
best in patient care.
He is survived by his widow, the former
Emily Louise Holt, a brother, and two
sisters.
Everett S. Diggs, M.D.
Albert E. Goldstein Memorial
Fund Organized
Officers have been recently chosen for
the Dr. Albert E. Goldstein Memorial Fund
which will honor the many contributions to
the medical profession and to the community
by the late physician whose death was
recently announced.
Offices of the fund, which will have head-
quarters in Suite 912, Fidelity Building,
Baltimore, Maryland, are as follows: Presi-
dent, Louis J, Kolodner, M.D., Vice Presi-
dents: John C. Krantz, Jr., Ph.D., Albert
A. Shuger, Leonard A. Siems; Treasurer,
Frank Fisher; Secretary and Assistant
Treasurer, Moses W. Rosenfeld. Members
of the Committee include the following:
John Askin. M.D., Louis Bachrach, M.D.,
Louis Diener, M.D., Robert B. Goldstein,
M.D.. Milton Kirsh. M.D., Irving R. Lo-
witz. M.D.. Nathan E. Needle, M.D., Marvin
S. Plant, H. Melvin Radman, M.D., Martin
A. Robbins, M.D., Louis Sachs, M.D., John
Sargeant, Herman Seidel, M.D., Milton
Sherry, M.D., Abraham Silver, M.D.,
William H. Triplett, M.D., Sheldon Wengel,
and Israel S. Sinberg, M.D.
The committee was formed after many
friends of the late Dr. Goldstein spontane-
ously proposed the establishment of a
memorial tribute. They cited his long and
distinguished career at Sinai Hospital and
Levindale, his leadership of the Medical and
Chirurgical Faculty, and his life-long in-
fluence upon and contributions to his
students and colleagues at the University
of Maryland as a mark of the boundless
energy and unlimited talents possessed by
Dr. Goldstein.
A goal of $50,000 with the aim of initiat-
ing programs, lectureships and awards of
interest to the young physician.
Contributions to the fund, tax exempt,
may be made payable to the Albert E. Gold-
stein Memorial Fund Incorporated. 912
Fidelity Building. Baltimore. Maryland
21201.
October, 1966
r ^. jFricbentonlt)
1879= 1966
On May 22, 1966, death came to Edgar
B. Friedenwald, the last surviving member
of the famous family and dynasty of Balti-
more physicians and scholars which began
with his father Dr. Aaron Friedenwald, who
graduated from the old Maryland Medical
College in 1860 and who was a prominent
practitioner and ophthalmologist in Balti-
more throughout the last century. Dr. Edgar,
as he was often affectionally called, had
been in failing health for a number of years.
Death came at Mercy Hospital where he
had been Chief of the Pediatric Service from
1923 to his retirement in 1950.
Dr. Edgar's father had been active in the
Medical and Chirurgical Faculty. In 1890
he delivered a dedicatory address at the old
Mercy Hospital in Baltimore at which
hospital many of the older Alumni received
their training. Seventy-three years later, his
son Edgar delivered the dedication address
at the opening of the new Mercy Hospital.
Two older brothers of Dr. Edgar, Harry
and Julius, were professors of ophthalmology
and gastroenterology respectively, in the
School of Medicine in the University of
Maryland. Another brother, Bernard, prac-
ticed dentistry following graduation from
the Baltimore College of Dental Surgery.
A son, Jonas, died a few years ago; a well
known figure in the field of ophthalmology.
At the time of his death. Dr. Edgar had
been compiling data on a history of pedi-
atrics in Maryland for future publication
as a book. He was also the author of many
articles on children's diseases.
Dr. Friedenwald was born in Baltimore
on November 20, 1 879, at a period when
pediatrics was not considered yet a full
specialty. His early education began in the
r<-/. 51. Xo. 4
t>kl Scheibc School uhich was associaloil
with Zion Lutheran Church, graduating
Irom this school and later from the Baltimore
City College in the Class of 1899. He was
a member of the College of Physicians and
Surgeons in the Class of 1903. Following
his graduation, he settled in Pun.xsutawny.
Pennsylvania, as a coal-mine surgeon and
general practitioner for the local community.
His only child. Aaron, now an army oHicer.
was born in Charleston. West Virginia.
After a few years the young pediatrician-
to-be decided on postgraduate training and
after spending a year at Johns Hopkins
Hospital, he sojourned to Berlin for further
work and studies with the eminent professors
Finkelstein and Huebner. At that period
Germany was the mecca for postgraduate
training in most specialties and particularly
in the field of medicine and pediatrics.
Upon his return to Baltimore in 1911, Dr.
Friedenwald began his practice of pediatrics
with an office at 1528 Madison Avenue. His
teaching career also started at that time and
he taught his specialty at Mercy Hospital
and at the old Hebrew Hospital (now the
Sinai Hospital of Baltimore). His ability
was shortly honored by his appointment of
Chief of Pediatrics at the Mercy Hospital
and later at the Sinai Hospital. At about the
same time, he joined the Medical Reserve
Corps and during World War I served as
a regimental surgeon with the 26th Infantry
Regiment first on the Mexican border and
later with the 38th Infantry at old Fort
Oglethorpe. Georgia. In 1916 he served
in France as a major in the Third Infantry
Division's 38th Regiment near Chateau
Thierry and took a part in the Battle of the
Marne. Upon his military discharge at the
end of World War I, he returned to the
United States and to his practice of medi-
cine. At his funeral on May 24th, full mili-
tary honors were accorded him at the time
of his burial in the Arlington National
Cemetery.
In the years 1919 to 1921, he played an
important part in the consolidation of the
University of Maryland School of Medicine
with the old College of Physicians and
Edgar B. Friedenwald. m.d.
Pmfttsor of Oinical Paltatnci, Emrnlus
I'NIVERSITV OK MARVl.A.M)
W t. tiis friends colleagues and former '■ludenl', lirrrbv
honor him, in appreciation of his lo\al and faithful M'r%ic'e
to all children; to Mercy Hospital Pediatrics; and to the
medical school. ^ A-« a permanent symbol of our esteem and
re^tpecl, we do hereby and hereunto affix our hand and
seal this twelfth day of April in the year nineteen hundred
Surgeons. Later, through Dr. Friedenwald's
leadership the department of pediatrics at
Mercy Hospital became one of the leading
facilities in the State for the management of
illnesses of children. The word pediatrics
at the Mercy Hospital was synonymous with
the name Dr. Edgar. He rose rapidly in
faculty rank and became Professor in the
mid 1920's.
Following his retirement he suffered a
continued series of cerebral vascular oc-
clusions which forced his retirement from
active teaching and practice; however, he
kept in touch with the affairs of the medical
world and particularly in the field of pedi-
atrics. His presence at meetings was a
familiar one and his kindly and friendly
smile was always evident. In 1953 he was
honored by pediatricians and by his Mercy
and University Hospital colleagues at a
testimonial dinner. In 1959 he was awarded
the Annual Medical Alumni Award and
Gold Key for outstanding contributions to
medicine and service to mankind. He was
an advisor, consultant to the younger men,
an able clinician, investigator and adminis-
trator. He was indeed an inspiration to his
colleagues and many friends throughout the
city. State and nation.
Samuel S. Click, M.D., F.A.A.P.
October, 1966
£
likj
OFFICERS
President
Howard B. Mavs. M.D.
President-EIect
John O. Sharre
, M.D.
Vice-Presidents
Benjamin M. Stein, M.D.
Patricia Dood, M.D.
Raymond M. Cunningham, M.D.
Treasurer
Walter E. Karfgin, M.D.
Executive Director
William H. Triplett. M.D.
Executive Secretary
Mrs. Louise Girkin
Board of Directors
William H. Kammer. Jr., M.D.
Robert B. Goldstein, M.D.
John D. Young, M.D.
Harry C. Bowie. M.D.
Theodore Stacy. M.D.
Wilford H.Townshend, Jr., M.D.
John C. Dumler, Sr., M.D.
W. Kenneth Mansfield, M.D.
J. Howard Franz, M.D.
(ex-officio)
C. Parke Scarborough, M.D.
(ex-officio)
Nominating Committee
J.
Howard Fran
(ex-officio)
z, M.D.
c.
Parke Scarborough,
(cx-offiaaj
M.D.
IJ
McClelland
Dixon,
M.D.
J A
MES R. Karns
M.D.
Et
ward F. Cott
ER, M.D
Representatives
General Alumn
to
Counc
il
H
3WARD B. Mai
i-x-offiao)
s, M.D.
Representatives
Editorial Board
To l.c iiami-d.
, BULLETIN
Re
Fa
presentatives
culty Board
to
To
be named.
(3-year terra began June, 1965)
C. Parke Scarborough, M.D.
Howard B. Mays, M.D.
ALUMNI ASSOCIATION
SECTION
President's Letter
Fellow Medical Alumni:
The election to the presidency of the Medical Alumni
Association is a very real honor and will. I hope, afford
an opportunity to be of service in this area of Uni-
versity activity. The excellent work of my predecessors
is a real challenge and the results of the efforts of the
many dedicated members of the Association will, I hope,
be given further impetus during the coming year. Much
progress has been made in recent years assuring the
Alumni Association of a rightful place as a constructive
force in the affairs of the University as related to past
and future graduates of the Medical School.
Interest in the Association has been steadily in-
creasing. The present membership numbers 1988 of a
total of 4,100 known living graduates of the Medical
School. There are about 400 graduates over 50 years
of age whom we are pleased to honor in a very special
category. These really impressive figures, among the
highest in the country, give some indication of the
place of Maryland graduates in the medical world and
a suggestion of the capacity for constructive influence
in furthering the stature of the University. That the
number of active members is not greater is perhaps more
a matter of effective communication than apathy and
I feel confident that a steadily increasing interest and
response will be forthcoming.
An effective Alumni Association must have the con-
tinuing interest and active support of all graduates if
the grand tradition of the past and the very certain
bright future of the University of Maryland Medical
School is to continue. The effective future of the Alumni
Association as a beneficial force depends in a significant
measure upon the recognition of changes that have
taken place within the Medical School, the associated
hospitals, and, in fact, of all areas of medical activity
throughout the land. New faculty appointments are
being continuously made in order that the scope and
excellence of teaching may continue. We must show
.xiv }'i>l. 51, No. 4
that they arc welcome and that their continuing eilorts
arc appreciated in an atmosphere of mutual interest.
The functions of the Alumni Association have been
increasing and among the foremost capacities for service
is the development and maintenance of a repository of
information relating to every graduate. This cumulative
information must be of a degree of completeness and
availability as to be immediately available not only
for Association purposes but equally for the Medical
School, the important graduate Medical and Surgical
Associations, the publications of the University and for
cooperation with the General Alumni Association.
I believe that the Medical Alumni Association must
remain a separate entity. The existence of a General
Alumni Association is important to the affairs of the
University of Maryland as a whole. We have in the
past and I believe we will continue to be cooperative
and a supporting factor in the General Alumni Associa-
tion. However the Medical School has a very old and
honorable tradition and must continue to enlarge its
sphere. Many graduates have expressed a desire for a
separate identity and we proposed to maintain and
energetically support this concept of Alumni organiza-
tion.
Though the numbers of graduates is great and the
interest of many in the Association and School has
been effectively demonstrated, our affairs, have, in
fact, been carried on by a dedicated relatively small
number. Geographic distribution must be considered
in the interests of an effective Board. However your
very enthusiastic support is needed and your suggestions
and contributions in the conduct of the affairs of the
Association are earnestly solicited.
Howard B. Mays, M.D.
President
Roster of Senior Aluiniii
Since 1964, Alumni of the University of
Maryland. Baltimore Medical College and
College of Physicians and Surgeons who
have been graduated more than fifty years
had been specially and appropriately listed
once each year in the pages of the Bulletin.
With the celebration of the last half
century class in 1965. the Alumni of the
three schools have now officially merged as
they join the senior group.
So long as they shall live the individual
Alumni of the three schools shall be listed
annually in the Bulletin so that the identity
of these physicians can be properly main-
tained. In addition, the Medical Alumni
Association proposes to list all of the known
graduates of the School of Medicine.
The School and the Alumni Association
do not propose to forget these honored
Alumni subsequent to their receiving their
fifty-year diploma. Instead the younger
men might well refer to this senior group
for advice.
The following Alumni of the University
of Maryland. Baltimore Medical College or
the College of Physicians and Surgeons have
been in practice fifty years or longer:
Senior Alumni
William Clay Abel, M.D., '01, BMC
2314 Frace Ave.
Orlando. Fla.
A. W. Adkins, M.D., '12, P&S
361 HillsboroSt.
Lexington, Ky. 40505
Andrew A. Anderson. M.D., '12. P&S
1101 Deseret Bldg.
Salt Lake City, Utah
James Leiand Anderson, M.D.. '08, UofM
213 Butler Ave. or 68 B Vardry St. Med. Ct.
Greenville, S. C. 29607
Charles W. Armstrong. M.D., '14, UofM
629 Mitchell Ave.
Salisbury, N.C. 28144
Richard T. Arnest, M.D.. '16, UofM
Hague, Va. 22469
Walter Cathcart Arthur, M.D., '97, UofM
2225 Fifteenth St.
Cuyahoga Falls, Ohio 44223
Wm. Richard Arthur, Md., '97, UofM
2627 S.E. 27th Ave.
Miami, Fla. 33133
Oscar T. Barber, M.D., '08, P&S
Health Officer
53 Temple St.
Fredonia, N. Y.
Yates M. Barber. M.D., '14, UofM
275-3
Warsaw, Va. 22572
Carl J. Baumgartner. M.D., '11, P&S
4841 River Point Rd.
Jacksonville. Fla. 32207
George A. Bawden. M.D.. '16, UofM
1110 The Broadview
Baltimore. Md. 21210
Philip Bean. M.D.. '13. UofM
Great Mills, Md. 20634
Elmer Jos. Beaulieu. M.D., '07, BMC
215 South Ave.
Whitman, Mass. 02382
Lt. Col. C. L. Beaven. M.D.. '08. BMC
1417 Burton wood Dr.
Alexandria. Va. 22307
William F. Beckner. M.D.. '11, BMC
713 West Virginia Bldg.
Huntington. W. Va.
Frederick V. Beitler. M.D.. '06. UofM
1014 Francis Ave.
Baltimore. Md. 21227
Harry J. Bennett. M.D., '06, BMC
121 N. Julian St.
Ebensburg, Pa. 15931
r,./. .-I. Xo. 4
.irjwfxi .issoci.irio.y sncriox
Clarence Irvint; Benson. M.D.. 'O';, UofM
Box 123
Port Deposit. Md. 21904
IJuaai H. Benson. M.D.. UofM
Hampton House. Apt. 204
204 H. Joppa Rd.
Baltimore. Md. 21204
Harry Melchior BilTar. "12, P&S
144-31 14th Ave.
Flushini;. N.Y. 11357
Col. Harry Alo\sius Bishop. M.D.. '1
UofM
37 IS Manor Road
Chevy Chase. Maryland 20015
Dr. Rafael Bernabe. "13, P&S
6 1 Savador Brau St.
San Juan, P. R.
William P. Black. M.D.. '14. P&S
111 Capitol St.
Charleston, W. Va. 25300
Lowrie W. Blake. M.D.. '14. UofM
5609 7th Ave. Dr. W.
Bradenton. Florida 33505
Walter D. Blankenship, M.D., '10, P&S
3 1 Sunset Place
Lancaster, Pa.
James G. Blovser. M.D.. "05. P&S
30S Rose Blvd.
Akron. Ohio 44302
Ray Maxwell Bobbitt, M.D., '13, P&S
1139 4th Ave.
Huntington, W. Va.
O. H. Bobitt, M.D., '14, P&S
863 24th Ave., N.
St. Petersburg. Fla. 33713
Alvah P. Bohannan. M.D.. '05. UofM
Virgilina, Va. 24598
Lawrence F. Boland. M.D., '11. BMC
P. O. Box 339
Frankfort. Kentucky 40601
Wm. P. Bonar. M.D.. '06. P&S
1006 Tomlinson Ave.
Moundsville. W. Va. 26041
Robert A. Bonner. Sr., M.D.. '12. UofM
51 West Main Street
Waterbury. Connecticut 06702
Charles F. Bove. M.D.. "13. BMC
70 E. Main St.
Patchoaue, N. Y. 11772
Wm. Ward Braithwaite. M.D.. "09. UofM
3 16 Jasmine Ave.
Corona Del Mar. Calif. 92625
Lee Bransford. M.D.. '10. BMC
12S2 May fair Rd.
Jacksonville. Fla. 32207
Thomas Latham Bray. M.D.. 16. UofM
Box 576
Plymouth, N. C. 27962
Harrison L. Brchmer. M.D.. "10. P&S
106 Girard Blvd.. S.E.
Albuquerque. N. Mexico 87106
James C. Brogden. M.D.. '14, UofM
210UticaSq. Med. Ctr.
1980UticaSq.
Tulsa. Okla. 74114
Charles R. Brooke, M.D., '16, UofM
VA Hospital
East Orange, N. J. 07019
Frank J. Broschart, M.D., '11, BMC
8 Russell Ave.
Gaithersburg, Md. 20760
Morton Brotman, M.D., '14, UofM
212SouthOrange Ave.. Apt. #10
South Orange. N. J. 07079
Archie Eugene Brown, M.D., "1 1, UofM
918 Poinsett Highway
Greenville, S. C. 29609
Joseph Edward Brumback, M.D., '09, BMC
Medical Arts Bldg.
Baltimore, Md. 21201
B. Bruce Brumbaugh, M.D., '16, UofM
5609 Main St.
Elkridge, Md. 21227
Jesus Maria Buch. M.D.. '13. UofM
1004 E. 36th St.
Baltimore. Md. 21218
Sidney Eli Buchanan, '12, UofM
390 S. Union St.
Concord, N. C.
Henry F. Buettner, M.D., '16, UofM
5005 Edmondson Ave.
Baltimore, Md. 21229
Louis Arthur Buie. M.D., '15, UofM
200 First St., S.W.
Rochester, Minn. 55901
Frank Burden. M.D.. '05. UofM
if 3 Bagshaw Ave.
Brishton. South Australia
October. 1966
BULLETIN OF THE SCHOOL OF MEDICIXE. UXWERSITY OF .\L-!RVL.-tXD
J. J. Burne, M.D., '10, P&S
101 N. Grove St.
EastOrange. N.J. 07017
Ira Burns, M.D., '05, UofM
2800 N. Atlantic, Apt. 605
Daytona Beach, Fla. 32018
Julian G. Busby, M.D., '04, UofM
901 W. Henderson St.
Salisbury, N. C. 28144
Lawrence A. Cahill, M.D.. '11, BMC
361 Lafayette St.
Newark, N.J. 07105
Charles A. Cahn, M.D., "15, UofM
2145 W.Baltimore St.
Baltimore, Md. 21223
Fred Glover Campbell, M.D., '11, BMC
Warren, Maine 04864
Jesse W. Campbell, M.D., "09, BMC
923 Philadelphia St.
Indiana. Pa.
Ovid Sylvester Campbell, M.D., '10, P&S
Grafton, W. Va.
Harry Arthur Cantwell, M.D., '06, UofM
Cecil Ave.
NorthEast,Md. 21901
Honorio F. Carrasquillo, M.D., "16, UofM
Hotel Commodore
42nd & Lexington Ave.
New York, N.Y. 10017
Manuel G. Carrera, M.D., '14, P&S
101 N. Union St.
Fajardo, P. R. 00648
Col. Henry P. Carter, M.D., "03, UofM
3445 B S. Stafford St.
Arlington, Va.
Arthur Casilli, M.D., '14, UofM
618 Newark Ave.
Elizabeth, N. J. 07203
Guiseppe Caturani, M.D., "10, UofM
348 E. II 6th St.
New York, N.Y. 10029
Michael Edward Cavallo, M.D.. '16, UofM
265 Lafayette St.
New York, N.Y. 10012
James Jennings Chandler, M.D., '16, UofM
1 32 N.Washington St.
Sumter. S.C. 29150
Lucien Romeo Chaput, M.D., '16, UofM
3 Washington Sq.
Haverhill, Mass. 01830
Louis Chargin, M.D., '02, BMC
1 W. 85th St.
New York. N.Y. 10024
Charles Peter Clautice, M.D., '12, UofM
3013 St. Paul St.
Baltimore, Md. 21202
Hubert Claytor, M.D.. '86, UofM
Hopkins. S. C.
Morris D. Cohen, M.D., "04, P&S
1534 East Speedway
Tucson, Arizona 85719
Ralph Cohen, M.D., '15, UofM
231 1 University Blvd. West
Silver Spring. Md. 20902
Joseph Coleman, M.D.. '04. UofM
455 West 23rd St.
New York. N.Y. 10011
Clarence E. Collins, M.D., '02, UofM
"The Hygeia" Hall Highway
Crisfield,Md. 21817
Wm. Stanislaus Conway, M.D., '10, UofM
3210 E. Perkins Ave.
Sandusky, Ohio
Everett L. Cook, M.D., '14, UofM
130SladeAve.. Apt. 306
Baltimore, Md. 21208
C. Melvin Coon, M.D.. '03, UofM
Milan, Pa.
Everett Roy Cooper, M.D., '12, P&S
Troy. W. Va.
Earle Somerville Coster, M.D., '06, UofM
Solomons, Md. 20688
George C. Coulbourne, M.D., '10, UofM
Marion, Md. 21838
Franklin Clyde Craven, M.D., "13, UofM
525 Sunset Ave.
Ashboro, N. C.
Henry L. Criss, M.D., UofM
218 Adams St.
Fairmont, W. Va.
Denis J. Cronin, M.D., '10. UofM
1007 4th Ave.
Huntington, W. Va.
Gilbert L. Dailey, M.D., '14, UofM
618 3rd St.
Harrisburg, Pa. 17101
Vol. 51, No. 4
ALUMM .ISSOCIATIOX SECTION
M. Tolbert Dalton. M.D., '06. UofM
6811 50th Ave., N.E.
Seattle 15. Wash.
Charles D. Daly. M.D.. '10. P&S
139 Warrenton Ave.
Hartford, Conn. 06105
George Davis. M.D., '08, UofM
28 South Church St.
Waynesboro. Pa.
Theodore McCann Davis. M.D.. '14. UofM
108 Vannoy St.
Greenville. S. C.
Harry Deibel. M.D.. 12. UofM
1226 Hanover St.
Baltimore. Md. 21230
Walter L. Denny. Jr.. M.D.. '14. UofM
3908 N. Charles St.
Baltimore. Md. 21218
James DePasquale. M.D.. "08. BMC
530 E. 234th St.
NewYork. N. Y. 10470
James E. Diehl. M.D.. '11. UofM
1 627 Hanover Ave.
Richmond 20. Va.
Louis Diener. M.D.. '15, UofM
2511 Eutaw Place
Baltimore. Md. 21217
Wm. J. Dillon. M.D.. '16. UofM
162 Maple St.
Springfield, Mass. 01105
J. D. Dinsmore. M.D.. '09, UofM
Port Clyde
Nova Scotia. Canada
Edward P. Disbrow. M.D., '08. P&S
15 Irving St.. Apt. 9
Worcester. Mass. 01610
James Sylvester Dixon, M.D., UofM
33 Parsonage St.
Pittston. Pa.
Harr>' C. Donahoo, M.D.. UofM
2428 Edgmont Ave.
Chester. Pa.
James Corbin Doughty. M.D., UofM
Onancock, Va.
Col. Chauncey E. Dovell, M.D., '14, UofM
62 S. Boxwood St.
Hampton. Va. 23369
John H. Doyle. M.D.. '02. P&S
775 Somerset Ave.
North Dighton. Mass. 02764
Joseph Lee Dowling. M.D.. '15. UofM
207 Waterman St.
Providence. R. I. 02906
Manuel Ducno Y Ducno. M.D.. '05, UofM
571 West 139th St.
NewYork, N.Y. 10031
James Fender Easton. M.D,. "13. P&S
45 Rosemary Lane
Romney. West Virginia
Vivian P. Edwards, M.D.. UofM
27 Hillside Ave.
Edwardsville. Kingston, Pa.
Michael Joseph Egan, Jr.. M.D.. '15. UofM
618 Maupas Ave.
Savannah, Ga. 31401
Samuel E. Enfield, M.D., "13, P&S
116 South Liberty St.
Cumberland. Md. 21502
Wilmer C. Ensor, M.D., '03. BMC
441 Swallow Dr.
Miami Springs, Fla. 33166
Richard Esslinger, M.D., '14, UofM
3720 Glenmore Ave.
Baltimore. Md. 21206
John Evans, M.D., '03. BMC
321 Regester Ave.
Baltimore, Md. 21212
Remo Fabbri, M.D., '09, BMC
1731 MarkleySt.
Norristown, Pa.
Dawson L. Farber. M.D.. '13. BMC
305 Woodlawn Rd.
Baltimore, Md. 21210
Lee K. Fargo, M.D., '15. P&S
8155 Loch Raven Blvd.
Baltimore. Md. 21204
George L. Faucett. M.D.. '03. P&S
908 Walnut St.
Gadsden, Ala. 35901
Lloyd H. Feick. M.D.. UofM
807 N. 10th St.
Reading. Pa.
Israel J. Feinglos. M.D., '16. UofM
2002 E. Pratt St.
Baltimore, Md. 21231
October, 1966
BULLETIX OF THE SCHOOL OF MEDICIXE. UXirERSlTV OF MARVLAXD
Wm. T. Ferneyhough, M.D.. "16. UofM
202 >/2 South Scales
Reidsville, N. C. 27320
Antonio Fernos-Isern, M.D.. '15. P&S
1710 New House Office Bldg.
San Juan, P. R.
Charles Wm. Finnerty. M.D.. "13, P&S
440 Broadway
Somerville, Mass. 02143
Frank P. Firey, M.D., '10. UofM
2224 N. E. 46th St.
Portland. Ore. 97213
Edward E. Fitzpatrick. M.D.. '15, P&S
317 36th Ave.. N.E.
St. Petersburg. Fla. 33704
Paul N. Fleming, M.D.. '13. UofM
8627 Fenton St.
Silver Spring. Md. 20910
Edgar T. Flint. M.D., "01. BMC
44 Somerset St.
Raritan. N. J. 08869
Ernest F. Flora. M.D., '13, UofM
Boones Mill. Va.
Wm. H. Flynn. M.D.. '16. UofM
126 Main St.
Bristol, Conn. 06010
Fred T. Foard. M.D., '16, UofM
701 Beaver Dam Rd.
Raleigh. N. C. 27607
H. M. Foster. M.D.. '10. UofM
Ilchester Rd.
EllicottCity,Md. 21043
Raymond K. Foxwell. M.D., '16, UofM
4103 N. 4th
Arlington. Va. 22203
Ernest Wm. Frey. M.D.. '12. UofM
1928 Pennsylvania Ave.
Baltimore, Md. 21217
Edgar B. Friedenwald. M.D.. "03, P&S
1701 EutawPl.. Apt. 1-B
Baltimore, Md. 21217
James C. Frye. M.D.. '1 1. BMC
407 First St.
Williamsburg, Pa.
Wm. L. Funkhouser. M.D.. "04. UofM
47 Peachtree Park Rd.
Atlanta. Ga. 30309
Charles W. Gardner. M.D., '01, UofM
49 Toilsome Hill Rd.
Bridgeport, Conn. 06604
George W. Gault. M.D.. '10, UofM
112 Walnut St.
Harrisburg. Pa.
W. Frank Gemmill, M.D., '13, UofM
121 W. Springettsbury Ave.
York. Pa.
Dawson Orme George. M.D.. '12, UofM
Denton, Md. 21629
Wm. Thos. Gocke. M.D., '11. P&S
8265 S.W. 150th Dr.
Miami, Fla. 33156
Leo Goldbach. M.D., '05. UofM
212 Stratford Rd.
Baltimore, Md. 21218
Albert Goldey. M.D., '12, UofM
210 W. lOlstSt.
New York. N. Y. 10025
Harris Goldman, M.D.. '10, P&S
3507 Garrison Blvd.
Baltimore. Md. 21215
Harry Goldmann, M.D.. '16, UofM
7121 Pk. Hgts. Ave.
Baltimore. Md. 21215
Harry Goldsmith. M.D.. '13. UofM
3109 Marnat Rd.
Baltimore. Md. 21208
Luis Felipe Gonzalez. M.D., '15, P&S
BoxB
Rio Grande, P. R.
Attie Thompson Gordon. M.D.. "14. P&S
Spencer. W. Va. 25276
Gustave A. Gorisse, M.D.. '1 1, BMC
7329 Kings Run Rd.
Dayton, Ohio 45459
Don U. Gould. M.D., '05. BMC
N. Main St.
Sherburne. N. Y. 13460
Garland Grazier. M.D., UofM
Hollsopple, Pa.
Charles Jacob Greenstein, M.D.. '12. BMC
300 Main St.
New Britain. Conn. 06051
George F. Grisinger. M.D.. '10, P&S
2861 Piedmont Rd.
Charleston. W. Va.
Vol. .^1. X,K 4
.lI-iMXr .ISSOCIATIOX SBCTIOX
Julius E. Gross. M.D., "07. UofM
9576 Collins Ave.
.Surfside. Fla. 3.M54
Bowers Hewitt Growt. M.D.. "16. UofM
.Medical Center
.Addison. Mich. 49220
Humphrey W. Gwynn. M.D.. "16. UoI'M
.■^20 N. Magnolia
Orlando, pla. 32802
Glenn G. Haight. M.D.. '10. BMC
.Audubon. .Minn. 5651 1
Edward St. C. Hamilton. M.D.. M 1. UofM
Oak Hill. W. Va.
Nathan S. Hanellin. M.D.. '1 1. UofM
152 182nd St.
Brooklyn. N. Y. 11209
Cecil Strake Ha.ssell, M.D.. "14. UofM
2939 S.W. 5th St.
Miami, Fla. 33135
Cecil Hassell. M.D.. '14. UofM
507 E. Carolina Ave.
Crewe. Va.
Herman E. Hasseltine, M.D.. "04. UofM
Bristol. Vt. 05443
Leonard Hays, M.D., '13, UofM
5201 Baltimore Ave.
Hyatisville. Md. 207S1
John Roy Hege, M.D., '16. UofM
905 Martin Drive
Concord. N. C. 28025
Howard Carrington Heilman. M.D.. UofM
Elderton. Pa.
Isidor Heller. M.D.. '13, UofM
49 Brandon Rd.
Upper Darby. Pa.
Frederick H. Herrman, M.D.. '07. UofM
1710 E. 33rd St.
Baltimore. Md. 21218
Arthur Wm. Higgins, M.D.. "07, UofM
McLain Bldg.
Wheeling. W. Va.
Robert B. Hill, M.D., '15. UofM
Southern Pines, N.C.
Simon VVickline Hill, M.D.. UofM
Regent, N. Dakota
John J. H. Hilton, M.D.. "12. BMC
336 Haverhill St.
Lawrence, Mass. 01840
Isadorc Hirschman, M.D., "11. UofM
618 11th Ave.
Huntington, W. Va.
Henry Hiram Hodgin. M.D.. UofM
Red Springs. N. C.
Maxcy Gregg HotTman, M.D.. UofM
Bunker Hill. \V. Va.
John F. Hogan. M.D.. '1 1. UofM
Box 113
Gibson Island, Md. 21056
Howard Steele Holloway, M.D.. "03. UofM
Perryman, Md. 21130
Francis Hutchinson. M.D.. "11. UofM
485 E. Howard St.
Pasadena. Calif. 91104
Manuel R. Janer, M.D., '12. UofM
697 West End Ave.
NewYork, N. Y. 10025
Leon Peter Jankievvicz. M.D.. "06. BMC
914 State St.
Utica. N. Y. 13502
Harry E. Jenkins. M.D.. '05. UofM
Farmville, Va.
Jesse J. Jenkins, M.D.. '14. P&S
Farmington. W. Va. 26571
William H. Jenkins. M.D., '15, UofM
2024 R St.. N.W.
Washington 9. D. C.
Frank Leslie Jennings, M.D.. "11. P&S
Medical Arts Building
Baltimore, Md. 21201
Charles Sterling Jernigan, M.D.. '97, BMC
350 Boulevard, S.E.
Atlanta, Ga.
William R. Johnson, M.D.. '15. UofM
403 Medical Arts Bldg.
Baltimore, Md. 21201
Kenneth B. Jones, M.D., '11, UofM
Church Creek, Md. 21622
Solomon Chas. Katzoff, M.D.. "04. UofM
Keystone Realty Co.
907 Whitelock St.. 1st Floor Apt.
Baltimore, Md. 21217
Charles Hutchison Keesor. M.D., '11. UofM
2302 Chapline St.
Wheeling. W. Va.
October, 1966
WLLETIN OF THE SCHOOL OF MEDICINE. VNIVERSITY OF MARYLAND
Col. Lloyd A. Kefauver, M.D., '06, BMC
665 S. Skinner Blvd.
St. Louis. Mo. 63105
Charles Keller, M.D., '98, UofM
222 W. Monument St.
Baltimore. Md. 21201
Roy R. Kerkow. M.D., '15, UofM
505 Yakima St.
Wenatchee, Wash.
George S. M. KiefTer, M.D.. '03, UofM
1010 Leeds Ave.
Baltimore. Md. 21229
George Alfred Kohler, Jr., M.D., '12, P&S
Smithburg.Md. 21783
Lawrence B. Kolb, M.D.. '08, UofM
6645-32nd St., N.W.
Washington, D. C. 20015
Charles Byron Korns, M.D., UofM
Sipesville, Pa.
Harry Stanley Kuhlman, M.D., '14, P&S
Sharptown,Md. 21861
Julius Jos. Kvatsak, M.D., UofM
3521 California Ave.
Pittsburgh. Pa.
Anthony W. Lamy. M.D.. "08, P&S
560 Newark Ave.
Elizabeth, N. J. 07208
Alston Howard Lancaster, M.D., '03, P&S
997 Main St.
Worcester, Mass. 01603
Philimon S. Lansdale, M.D., '02, UofM
100 E. Church St.
Frederick, Md. 21701
Wm. E. Van Landingham, M.D.. '05, BMC
328 Dyer Ave
West Palm Beach. Fla. 33405
Herbert Leonard Langer, M.D., '14, P&S
212 Beach 69th St.
Far Rockaway, N. Y. 1 1692
Frank V. Langfitt, M.D., '07, BMC
227 Carr Ave.
Clarksburg, W. Va.
Enrique Laisse y Rivera, M.D.. UofM
Sabana Grande, P. R.
Augustin R. Laugier, M.D., '14, P&S
Box 298
San Juan, P. R. 00902
Charles R. Law, Jr., M.D., '1 1. UofM
Berlin, Md. 21811
Oram R. Lawry. Sr.. M.D., '11, P&S
23 Oak St.
Rockland. Maine 04841
J. Walter Layman, M.D., '10, BMC
5 Public Square
Hagerstown, Md. 21740
Simon Geilech Lenzner, M.D., '12, UofM
187 Waterman St.
Providence 6, R. L
Letcher E. Trent. M.D., '10. P&S
209 DeWitt Rd.
Syracuse, N. Y. 13214
Morris B. Levin. M.D., '14. UofM
218 University Pkwy.
Baltimore, Maryland 21218
Addison LeRoy Lewis, M.D., UofM
Havre de Grace, Md.
Nolan D. C. Lewis, M.D., '14, UofM
Rt.#5
Frederick, Md. 21701
Louis Herbert Limauro, M.D.. '06. UofM
374 Charles River Rd.
Watertown. Mass.
R. Basil Linger, M.D., '15, P&S
321 W. Main St.
Clarksburg, W. Va.
Joseph Lipskey, M.D., '14, P&S
Odenton ( A. A. Co. ) , Md. 2 1 1 1 3
Bernard Livingston, M.D., '08, BMC
535 S. Shore Dr.
Miami Beach, Fla. 33141
Thomas P. Lloyd, M.D., "96, BMC
1030 Highland Ave.
Shreveport, La. 71101
Arthur M. Loope, M.D., '98, BMC
217 Sherbourne Rd.
Syracuse, N. Y. 13224
John Robert Lowery, M.D., UofM
Salisbury, N. C.
Charles H. Lupton, M.D., '16. UofM
1430 Meads Rd.
Norfolk, Va. 23505
John F. Lutz, M.D.. '14, UofM
72 Southgate Ave.
Annapolis. Md.
]'ol. M. Xo. 4
.IIAMXI .ISSOCIATIOX SECTIOX
Clyde C. Mack. M.D.. •04, UofM
S72 :4th St.
Winter Haven. Fla, 3.^SSl)
Isaac M. Macks, M.D.. "I 1. UofM
3506 Liberty Heights Ave.
Baltimore. Md. 21215
A. M. Magarian, M.D., "05. BMC
330 VV. Ocean Blvd.
Long Beach. Calif. 90S02
Charles L. Magruder. M.D.. 'U. UofM
1010 N. Bundy Drive
Los Angeles. Calif. 90049
John E. Maher. M.D.. "14. P&S
96 Third Ave.
Long Branch. N. J. 07740
Vernon L. Mahoncy. NLD.. "15. P&S
2725 E. Exeter
Tucson, Ariz. 85716
-Albert Eugene Mann. ^^D.. T2. UofM
182-5th St.
Stamford. Conn. 06904
Ernesto. Marr. M.D.. T3. UofM
516 Cathedral St.
Baltimore, Md. 21201
Wm. Reginald Marshall. M.D.. "08. BMC
22 Broad St.
Lynn. Mass. 01902
Wm. E. Martin, M.D.. '09, UofM
Randallstown, Md. 21133
Wm. T. Martin, M.D., UofM
605 McDaniels Ave.
Greenville, S. C.
Erwin Mayer. M.D.. '14. P&S
The Esplanade Apts.
Baltimore. Md. 21217
Frederick W. A. Mayer, M.D., '03, P&S
1830 James Ave.
St. Paul. jMinn. 55105
John Vincent McAninch. M.D., '14. P&S
308 W. Lincoln Ave.
McDonald, Pa. 15057
Frederick L. McDaniel, M.D.. '13, UofM
44 Northdown Rd.
Alexandria. Va.
Albert D. McFadden. M.D., '14, UofM
4313 Marble Hall Rd.
Baltimore, Md. 21218
Henry Hupp Mclniire. M.D.. '07. BMC
406 Green St.
Connellsville. Pa. 15425
George McLean, M.D.. "16, UofM
Medical Arts Bldg.
Baltimore, Md. 21201
Roscoc Drake McMillan. M.D.. UofM
Red Springs. N. C.
C. W. McPhcr.son, M.D.. '10, UofM
Box 969
Burlington. N.C. 27216
John L. Meeker. M.D.. '03. P&S
6 DeBarry Place
Summit, New Jersey 07901
Francis J. Mejias, M.D., "16, UofM
552 Miramar Ave.
Santurce. P. R. 00908
M. I. Mendeloff, M.D., '12. UofM
Box 921
Charleston 23, W. Va.
Harry B. Messmore, M.D., UofM
Addison. Pa.
Challice Haydon Metcalfe. M.D., "14, UofM
Sudlersville, Md. 21668
Isidore Michel, M.D., '11, UofM
870-5th Ave.
NewYork, N. Y. 10021
Samuel Miller, M.D., '12. BMC
2807 Arthur St.
Hollywood. Fla. 33020
William C. Miller, M.D., UofM
Gaithersburg, Md.
David C. Mock. M.D.. '04. P&S
215CajonSt.
Redlands, Calif. 92373
Daniel B. Moffett, M.D., UofM
1 150 Connecticut Ave., N.W.
Washington. D. C.
Alfred N. Moore. M.D.. "03. BMC
16 Pike St.
Oakland, 111. 61943
Emmett A. Moore, M.D., '08, UofM
Box 247
Newark, Ohio
Col. Alfred Mordecai. M.D., "14, UofM
806 S. Hawthorne Rd.
Winston-Salem, N. C.
October, 1966
BVLLETIX OF THE SCHOOL OF MEDICIXF. VXIJ-ERSITY OF MAKYLAXD
Charles G. Morgan. M.D., UofM
156 Santa Barbara St.
Corpus Christi, Texas
Samuel J. Morris. M.D., UofM
205 Kingwood St.
Morgantown. W. Va.
Theodore Morrison, M.D., "15. UofM
Apt. 704 West
100 W. Cold Spring Lane
Baltimore, Md. 21210
C. H. Moses, M.D., UofM
919 Linden Ave.
Sharon, Pa.
Charles L. Mowrer. M.D.. '13. UofM
159 W.Washington St.
Hagerstown, Md. 21740
Leo P. Musser, M.D., "13, UofM
500 Vine Hill Way
Martinez, Calif. 94553
Charles W. Myers. M.D.. '15, UofM
R.D. IS. Box 256
Indianapolis, Ind. 46224
Wm. Edgar Myles, M.D., UofM
White Sulphur Springs, W. Va.
Victor C. Nah, M.D., '13, UofM
301 North Van Buren St.
Wilmington. Dei. 19805
Walter Irving Nailer. M.D.. '10. BMC
121 Wickham Ave.
Middletown, N. Y. 10940
A. B. Nevling, M.D., '16. UofM
P. O. Box 558
Rochester, Minn. 55902
Benjamin Newhouse, M.D., "12. UofM
4213 16thSt., N.W.
Washington, D. C. 2001 1
Walter S. Niblett, M.D., "11, UofM
1141 Gypsy Lane East
Baltimore, Md. 21204
Frank Peter Nicholson, M.D.. '16. UofM
301 Boston Blvd.
Sea Girt, N. J. 08750
Charles Francis Nicol, M.D., '13, P&S
63 Prospect Pk., W.
Brooklyn. N. Y. 11215
Robert H. Noell. M.D., '16. UofM
207 Academy St.
Roxboro, N. C. 27573
Juan J. Nogueras, M.D., "15, P&S
468 Caribe St.
Box 1214
San Juan, P. R.
Lester D. Norris, M.D., '08, UofM
Fairmont General Hospital
Fairmont, W. Va. 26551
Arthur M. O'Connor. "09. BMC
39 Academy St.
Lee, Massachusetts 01238
Vincent J. Oddo. M.D., '16, UofM
65 S. Hill Dr.
Cranston. R. I. 02910
John Charles O'Neil. M.D.. '14, UofM
P.O. Box 158
Savannah, Ga. 31402
Gonzalo O'Neill, M.D.. '16, UofM
410 Prospect St.
East Orange. N. J. 07017
Walter A. Ostendorf. M.D.. '13, UofM
420 West Elsmere
San Antonio 12, Texas
John Ostro. M.D., '11. UofM
5234 Dorchester Ave.
Chicago, III. 60615
Samuel Watson Page. M.D.. UofM
Greenwood, S. C.
Julius G. Paider, M.D., '00, BMC
405 E. 72nd St.
New York, N. Y. 10021
Harold H. Palmer. M.D.. '08. BMC
36 S. Main St.
Plymouth. N. M. 03264
Wm. N. Palmer, M.D., '05, P&S
P. O. Box 558
Easton, Md. 21601
Paul Jones Parker. M.D., UofM
Hampton, Va.
James B. Parramore. M.D.. '09. UofM
523 Whitehead St.
Key West. Fla. 33040
Benjamin Parvey. M.D.. '07, BMC
636 Beacon St.
Boston, Mass. 02215
T. E. Patteson, M.D., '09, UofM
Dillwvn. Va.
Vol. 51. No. 4
ALUMNI ASSOCIATIOX Sru'TION
Ernest M. Perry. M.D.. UofM
1 25 Sunset Ave.
Rocky Mount. N. C.
Charles J. Pflueger, M.D.. '05, BMC
460 S. Ardmore St.
LosAngelcs. Calif. 90005
George Henry Ptlucger. M.D.. '06, BMC
40 Dole Ave.
Crystal Lake. III. (i0014
Lawrence D. Phillips. NLD.. "19. UofM
.i30l Newport Gap Pike
Wilmington. Del. I9S0S
W'm. Garfield Phillips. M.D.. UofM
Skiatook. Okla.
George Piness. NLD.. "13, UofM
240 S. LaCienga Blvd.
Beverly Hills, Calif. 90211
Linn F. Playse. M.D.. "06. UofM
4340 Juanita Way. South
St. Petersburg 5, Fla.
Walter W. Point. M.D., "H, UofM
Box 2567
Charleston 29, W. Va.
Guy R. Post, M.D., "16. UofM
11 16 S.Park Dr.
Fairmont, W. Va. 26554
John T. H. Powers. M.D.. '10. P&S
55 West St.
Leominster. Mass. 01453
Ivan Emerson Pratt, M.D.. UofM
Millerton. Pa.
Wilmer Marshall Priest, M.D.. "09, UofM
55 West 1 84th St.
New York 28. N. Y.
Manuel E. Pujadaz-Diaz. M.D.. "14. P&S
1611 Colon Ave.
Santurce. P. R. 00911
Clayton T. Ralls. M.D.. '04, P&S
Box 608
Winfield. Kansas 67156
Watson S. Rankin. M.D., '01, UofM
Methodist Home
Charlotte 5. N. C.
Moses Raskin. M.D.. '15. UofM
6221 Greenspring Ave.
Baltimore 9, Md.
Edwin R. Raymalcy. M.D., '04, UofM
1034 .South Ave.
Pittsburgh 21. Pa.
Harry Cornelius Raysor. M.D.. '13. Uof.M
St. Matthews. S. C.
Robert P. Reagan, M.D.. 08. BMC
345 Goundry St.
North Tonawanda, N. Y.
Ralph G. Reed. M.D., '08. BMC
330 Elmore St.
Central Islip. N. Y. 11722
Charles A. Reifschneider. M.D.. '16, UofM
104W. Madison St.
Baltimore, Md. 20101
Col. Walter L. Richards, M.D., '14, UofM
Box 1 1, Route 4
Charlottesville, Va.
Capt. Willard J. Riddick, M.D., '05. UofM
7426 Dominican St.
New Orleans, La. 70118
Harry Young Righton, M.D., '07, UofM
401 E. 45th St.
Savannah, Ga. 31405
John Wm. Robertson, M.D., '09, UofM
Onancock, Va.
Jacob Roemer, M.D.. '06, BMC
365 S. Westgate Ave.
Los Angeles, Calif. 90049
Joseph U. Rohr. M.D.. '14, P&S
3705 Bohan St., N.E.
Roanoke, Va. 24012
George Rosenbaum, M.D., '05, UofM
1030 Rock Creek Drive
Wyncote, Pa.
George Rosenbaum, M.D., '05. BMC
7608 Coventry Ave.
Philadelphia. Pa. 19126
Jacob L. Rosenstein, M.D., '05, P&S
568 Bergen Ave.
Jersey City, N. J. 07304
Paul Arndt Rothfuss, M.D., '23, UofM
1032 Rural Ave.
Williamsport, Pa. 17701
Wm. T. Ruark, M.D., '15. UofM
Pinecrest Sanatorium
Beckley. W. Va. 25801
October, 1966
BULLETIN OF THE SCHOOL OF MEDICIXE. UXH-EKSITV OF MARVLAXD
Louis Rubin, M.D.. '10, UofM
10510 Euclid Ave.
Cleveland 6, Ohio
John G. Runkel, M.D., '10. UofM
715 Charing Cross Rd.
Baltimore, Md. 21229
Francis F. Ruzicka, M.D., '16, UofM
800 N. Patterson Park Ave.
Baltimore. Md. 21224
Raymond Harrison Ryder, M.D.. "13, UofM
48 Central Ave.
Waterbury, Conn. 06702
Lucius C. Sanders, M.D., '15, UofM
20 S. Dudley St.
Memphis, Tenn. 38103
Harry Schniick, M.D.. '15, UofM
1203 San Diegiato St.
Encinitas, Calif. 92024
Leonard O. Schwartz. M.D., '12, P&S
3421 Pennsylvania Ave.
Weirton, W. Va.
William H. Scruggs, M.D., "13, UofM
Andrews, N. C.
George H. Seaks, M.D., '04, UofM
New O.xford, Pa.
Elias C. Segarra, M.D., '13. P&S
1803 Ponce de Leon Ave.
Santurce, P. R. 00929
Herman Seidel, M.D., '10, P&S
2404 Eutaw Place
Bahimore, Md. 21217
Roger K. Sell, M.D., '13, BMC
Torrington, Wyoming 82240
Charles L Shaffer, M.D., "07, BMC
725 East Main St.
Somerset, Pa.
Maurice E. Shamer, M.D., '10, UofM
3300 West North Ave.
Baltimore, Md. 21216
Albert C. Shannon, M.D.. '12, P&S
R. D. 1, Box 83
Mayport, Pa. 16240
J. D. Sharp. M.D., '12, UofM
Box 849, Shifting Shadows
Twenty-Nine Palms, Calif. 92277
Arthur A. Shawkey, M.D., '00, P&S
207 Beauregard St.
Charleston 1, W. Va.
Richard O. Shea, M.D., '14, P&S
25 Sanford Place
Bridgeport, Conn. 06604
Frank E. Shipley, M.D., '15, UofM
Savage, Md.
Ivy G. Shirkey, M.D., "14, P&S
Albemarle Apts.
1830 17thSt., N.W.
Washington, D. C. 20009
Wilbur F. Shirkey, Jr., M.D., '16, UofM
Riverview Terrace, Apt. 501
Charleston, W. Va.
David Silberman, M.D., '12, UofM
#508 Temple Garden Apts.
2601 Madison Ave.
Baltimore, Md. 21217
Albert George Singewald, M.D., '02, UofM
1613 E. North Ave.
Baltimore, Md. 21213
John Andrew Skladowsky, M.D. '12. UofM
Box 181, Route #1
Severna Park, Md. 21 146
Henry Oscar Sloane, M.D.. "OS. BMC
23 S. Hillside Ave.
Ventnor, N. J. 08406
Arthur Charles Smith. M.D., "10. P&S
90 Deer Hill Ave.
Danbury, Conn. 06810
Earl H. Snavely, M.D., '05, BMC
4800 San Amaro
Coral Gables, Fla. 33146
Frederick Snyder, M.D., '08, UofM
44 Clinton Ave.
Kingston. N. Y. 12401
Edward Wharton Sprague, M.D.. "03. P&S
86 Washington St.
Newark, N. J. 07102
Dallas C. Speas, M.D., "11, UofM
2598 Reynolds Rd.
Winston-Salem. N. C.
Hugh R. Spencer. M.D.. "10. UofM
3900 N. Charles St.
Baltimore, Md. 21218
Clarke J. Stallworth, M.D.. '12. UofM
Thomaston. Ala. 36783
Fred E. Steele. Jr., M.D.. "07, UofM
Florence. Mass.
I'ol. .■I'i, No. 7
ALU MX I ASSOCIATION SECTION
I'aiil Beadle Steele, M.D.. "15. P&S
7059 Jenkins Arcade
I'itisbiirgh, Pa. 15222
Harold Milton Stein, M.D.. "16. UofM
227 \V. Broadway
Paterson, N. J. 07522
Jacob J. Stcinfelder. M.D., 'OS. BMC
924 West End Ave.
New York. N.Y. 10025
Thomas \Vm. Stevenson. M.D., 'OS, P&S
4421 Montaire Ave.
Long Beach, Calif. 9080S
George L. Stickney. M.D.. "10, UofM
104 West University Pkwy.
Baltimore. Md. 21210
Frank Gregory Strahan. M.D.. "14, UofM
Williamsville. Vt,
George L. Straiib. M.D.. T 1. UofM
4117 Anderson Rd.
CoralGables.Fla. 33146
Charles Franklin Strosnider. M.D., "09,
UofM
P. O. Box 550
Goldsboro. N. C. 27530
B. F. Tefft. M.D.. •05, UofM
1 85 Washington St.
West Warwick. R. I.
Bernard Oscar Thomas. Sr., M.D., '06,
UofM
228 N. Market St.
Frederick, Md. 21701
John M. Thorup, M.D., '15, P&S
4927 N. E. 30th Ave.
Portland. Oregon 97211
Homer U. Todd. M.D.. '08. UofM
2108 St. Paul St.
Baltimore. Md. 21218
Grafton Dent Townshend. M.D., '1 1, UofM
1141 Roscomore Rd.
Los Angeles. Calif. 90024
William J. Trainor, M.D.. '03. BMC
326 Virginia Circle
Wilmington, Ohio
Richard Trevaskis. Sr,. M.D.. '11. UofM
220 Baltimore Ave.
Cumberland, Md. 21502
William H. Triplet!, M.D.. '11, BMC
1038 Lakemont Rd.
Baltimore. Md. 21228
Karl H. Trippett. M.D.. '11. P&S
Grafton. W. Va.
Jesse R. Tiickwiller. M.D.. '10, P&S
223 Monroe St.
Fairmont, W. Va.
Alfred Ullman. M.D., '02, P&S
1702 Eutaw Place
Baltimore. Md. 21217
Carl M. Van Poole, M.D., '16, UofM
Mt. Airy. Md. 21771
Wm. Lawrence Van Sant. M.D., '10. UofM
Hinton. W. Va.
Thurman Elroy Vass. M.D., '14, P&S
Box 167
Bluefield, W. Va. 24701
Frederick J. Waas, M.D.. '05, UofM
1804 Mayview Rd.
Jacksonville, Fia. 32210
Joseph Judson Waff, M.D., '15, UofM
Box 235
Shenandoah, Va.
Adam C. Walkup. M.D., '09, UofM
33 Water St.
St. Augustine, Fla. 32084
Wm. Benjamin Warthen, M.D., '05, UofM
Davisboro, Ga. 31018
Earl B. Weible, M.D., '10, BMC
Abercrombie, N. Dakota
Meyer A. Weinberg. M.D., '04, UofM
1724 Eutaw Place
Baltimore, Md. 21217
Maurice C. Wentz, M.D., '16, UofM
455 W. Market St.
York. Pa. 17404
Parker M. Wentz, M.D., '06, P&S
752 Kelly Drive
York, Pa.
Cleveland D. Whelchel, M.D., '13, UofM
1735 Riverside Drive
Gainesville, Ga. 30501
Edwin Vignes Whitaker, M.D.. '12. UofM
Box 625
Baton Rouge, La. 70821
October. 1966
BULLETIN OF THE SCHOOL OF MEDICLXE. UNirERSITV OF MARYLAXD
Col. Wm. A. Wickline. M.D., "95, P&S
232 Rutherford Drive
Danville, Calif. 94526
Java C. Wilkins. M.D., '1 1 , UofM
Box 446
Haw River, N. C. 2752S
David T. Williams, M.D., "14, UofM
21 Hall Ave.
Newark, Ohio
Louis V. Williams. M.D.. '11. P&S
Route 7
York, Pa.
Mayes B. Williams, M.D., "12, P&S
2000 Eoff St.
Wheeling, W. Va.
Wm. Frederick Williams, M.D., '16. UofM
122 S. Center St.
Cumberland, Md. 21502
Ernest L. Wilson, M.D., ' 11 , BMC
10509 Stone Ave.
Seattle 33, Wash.
Walter Michael Winters, M.D., "10, UofM
288 Broadway
Paterson, N. J. 07501
Francis R. Wise, M.D., '08, P&S
129 E. Market St.
York, Pa. 17401
Walter D. Wise, M.D., '06, P&S
1120 St. Paul St.
Baltimore, Md. 21202
John I. Wiseman, M.D., "07. P&S
215 Annie St.
Orlando, Fla. 32806
Eugene Bascom Wright, M. D., "09, UofM
340 Buckhannon Ave.
Clarksburg, W. Va. 26301
Silas G. Wright, M.D., '04, UofM
Shawboro. N. C.
Austin H. Wood, M.D., "14, UofM
Medical Arts Building
Baltimore, Md. 21201
Eugene Zeller, "15, UofM
2739 Eastern Ave.
Baltimore 24, Md.
Mark V. Ziegler, M.D., "15, UofM
OIney, Md. 20832
W. F. Zinn, M.D., "11, P&S
400 Coral Way
Ft. Lauderdale, Fla. 33301
I'ol. .^;, No. 4
(^lass
NOTES
}■()((/• acliici'cuicnts. jcUo',^' aliiiiniii.s.
arc of interest to your classmates. They
constitute a rezvard to the faculty, are a
chaltc)u/c to the younger physicians, and
arc an item of prestige for the Univer-
sity. Please cooperate with us by for-
warding news of yourself or any alumnus
to the BuLLETix. Thank you.
CLASS OF 1911
Dr. G. D. Townshend has moved from
his former residence to the Shangrila Apart-
ments, 1301 Ocean Avenue, Santa Monica,
California.
CL.\SS OF 1926
Dr. Bernard J. Cohen has announced the
association of Dr. Alan B. Cohen in the
practice of internal medicine with offices at
the Mar>lander Apartments, 3501 St. Paul
Street, Baltimore, Maryland.
CLASS OF 1927
Dr. E. Eugene Covington was recently ap-
pointed Senior Radiotherapist at the Me-
morial-Sloan Kettering Cancer Center in
New York City. Dr. Covington will also
join the Faculty of the Medical School of
Cornell University.
CLASS OF 1928
Dr. A. A. Silver has announced the as-
sociation of Dr. Harvey S. Feuerman of the
Class of 1962 for the practice of diabetes
mellitus and internal medicine. Dr. Silver
has offices at 2601 Madison Avenue, Balti-
more, Maryland.
CLASS OF 1929
Dr. Jacob H. Conn has been elected North
American Vice President in the Section of
Clinical Hypnosis of the Pan Ameriean
Medical Association.
CLASS OF lli.il
Dr. W'illiani M. Seabold hus announced
ihc opening ol his ollicc lor the practice of
adolescent medicine al 134 West I.anvale
Street in Baltimore.
CLASS OF 19.33
Dr. Stephen Sewell of 410 Essex Avenue,
Spring Lake, N. J., has retired as chief of
the gastroenterology section of the Veterans
Administration Hospital at Lyons, New
Jersey. Dr. Sewell will continue to live in
Spring Lake, New Jersey where he was
previously engaged in private practice and
where he has his permanent home. Dr.
Sewell will spend the winters in Florida
where he has a home on Majoca Island.
CLASS OF 1936
Dr. Milton H. Stapen, president of the
Williamsburgh General and Hampstead
General Hospitals in New York, was
recently appointed a consultant to the United
States Government on "Medicare" for
hospital based specialists.
Dr. Stapen also served as a member of
New York's Associated Hospital Service
"Blue Cross" and is a member of the Long
Island Hospital Planning Council. He
recently resigned a civil service position as
radiologist to the City of New York after
more than twelve years of service; however,
he remains an active member of the faculty
of the Down State Medical School.
Dr. Harry C. Bowie has announced the
association of Dr. David R. Will of the Class
of 1943 in the practice of general surgery
and with offices at 926 St. Paul Street in
Baltimore.
CLASS OF 1937
Dr. Samuel Jackson of Valley Stream,
Long Island, has been elected president of
the medical staff of the South Nassau Com-
munities Hospital. Dr. Jackson took office
for a period of two years beginning July 1.
A former secretary and vice-president of
the hospital's medical staff, he is also past
October, 1966
BULLETIX OF THE SCHOOL OF MEDICIXE. iWII-ERSITV OF MARVLJXD
president of the Nassau County Academy of
General Practice, a member of the Congress
of Delegates of the New York State
Academy of General Practice and a con-
sultant to the Psychiatric Faculty of the
Nassau Academy of Medicine.
CLASS OF 1938
Dr. Samuel Novey has been appointed to
the full time staff of the Sheppard and Enoch
Pratt Hospital. Dr. Novey will serve as
Director of Training. In announcing his
appointment, the hospital stated: "Dr. Novey
comes to Sheppard Pratt with a background
of some twenty-six years in psychiatry.
Throughout his professional career he has
been actively engaged in teaching. He is a
Training and Supervising Analyst in the
Baltimore Psychoanalytic Institute and an
Associate Professor of Psychiatry at the
Johns Hopkins University School of Medi-
cine. Dr. Novey is well known for his many
contributions to the scientific literature of
psychiatry and psychoanalysis."
Dr. Samuel Louis Fox has announced the
opening of his suburban office in the Pikes-
ville Professional Building, 7 Church Lane,
with his practice limited to ophthalmology.
CLASS OF 1942
Dr. Luis O. J. Manganiello of 1467 Harper
Street, Augusta, Georgia, has been named
a member of the State Board of Medical
Examiners of the State of Georgia. The
appointment was recently made by Gov.
Carl E. Sanders. Dr. Manganiello received
his training in neurosurgery at the Uni-
versity of Maryland under the late Dr.
Charles Bagley and has since been active
in the practice of this specialty in Augusta,
Georgia. He is the author of numerous
scientific contributions in the field of neuro-
surgery and to basic neurology.
CLASS OF 194.3
Dr. Harry Cohen has been promoted to
assistant professor in the department of
obstetrics of the School of Medicine. Dr.
Cohen is also president of the Physician's
Club of Baltimore of Plii Delia Epsilon
Medical Fraternity.
Dr. R. Louis Sapareto has announced the
opening of his office for the practice of
otolaryngology at 122 Enoza Avenue, Haver-
hill. Massachusetts.
Dr. David R, Will has announced his as-
sociation in the practice of general surgery
with Dr. Harry C. Bowie with offices at 926
St. Paul Street in Baltimore.
CLASS OF 1945
Dr. Frank J. Ayd, Jr. has organized and
begun publication of a new periodical en-
titled International Drug Therapy News-
letter. The Newsletter, to be published
monthly, is described as a concise, compre-
hensive coverage of important clinical and
research information on psychoactive drugs
and other medicine which act on the central
nervous system gathered from clinicians, re-
search investigators, hospitals, clinics and
the world's medical literature. Dr. Ayd
will serve as editor of the Newsletter.
Dr. Ayd, recently returned from a two
year residence in Italy, is offering the
journal at a yearly subscription price of
$7.00 with a rate of $4.00 for residents.
Publication and subscription offices are lo-
cated at 912 West Lake avenue, Baltimore,
Md.
CLASS OF 1947
Dr. George Winokur has been promoted
to Professor of Psychiatry at the Washington
University School of Medicine in St. Louis.
Dr. Winokur has been a member of the
Washington University Faculty since 1951.
CLASS OF 1948
Dr. H. Patterson Mack has joined the
Mead Johnson Research Center in Evans-
ville, Indiana, where he will serve as an
Associate Director of Clinical Research.
;■,./. .^7. .V,.. V
.ILL MM .ISSOCIATIOX SECTION
Mack. M.l).
In an announcement released b\ Dr.
lichard T. Arnold, president of the research
enter, he said Dr. Mack will concern him-
jelf chiefly with the development of clinical
jesearch programs for the company.
Before joining Mead Johnson, Dr. Mack
lerved as senior clinical pharmacologist at
Ihe Sterling-Winthrop Research Institute in
liensselaer. New York. Prior to that, from
I960 to 1964, he was engaged in research
t the Christ Hospital Institute of Medical
Research in Cincinnati where he headed the
oxicology and pathology section. At this
lime, he also served as lecturer in anatomy
't the University of Cincinnati. From 1950
\o 1960, Dr. Mack was associated with the
Jniversity of Maryland following his gradu-
jtion in the Class of 1948. He served first
is an intern at the University Hospital and
■hen a period of time in the Department
;if Pathology and Anatomy working under
|he direction of Dr. Frank H. J. Figge. Dr.
.'lack received his preliminary education at
iutgers University and Washington Uni-
ersity in St. Louis before coming to the
Jniversity of Maryland.
Dr. Roger S. Waterman has announced
he removal of his office to 8306 Liberty
load, Baltimore, for the practice of psy-
•rhiatry.
CLASS OF 1950
Dr. Wilbert H. McElvain (Colonel), M.C.,
J. S. A. F.. has been recently named Com-
nander of the 12th U. S. Air Force Hospital
it Cam Ranh Bay, Viet Nam. Prior to this
ippointment. Dr. McElvain served with
4eadquarters. Aerospace Medical Division
)f Brooks Air Force Base, Texas.
:>cfobcr, 1966
I'ol. Wilberl H. McElv
M.C.. l^S.A.F.
A combat pilot during World War II and
a native of Grove City. Pennsylvania, Dr.
McElvain is also holder of a Master of
Public Health Degree (MPH) in 1960 from
the University of California at Berkeley.
CLASS OF 1951
Dr. Leonard M. Lister has announced the
removal of his office to Park Towers East.
7111 Park Heights Avenue, Baltimore,
Maryland.
CLASS OF 1956
Dr. C. Herschel King, who has until
recently held the post of Assistant Professor
of Anesthesiology at the Duke University
Medical Center, has accepted an appoint-
ment on the Staff of the Memorial Hospital,
Cumberland, Maryland.
CLASS OF 1959
Dr. John F. Cadden, Jr. of New York
City has been appointed assistant director
of the medical department of the National
Foundation-March of Dimes.
Before accepting his new post. Dr. Cadden
was consultant in maternal and child health
to the Prince Georges (Maryland) County
Health Department. Following his gradu-
ation from the School of Medicine, he was
intern and then resident in pediatrics at the
University Hospital. During 1962-65 he
BULLETIN OF THE SCHOOL OF MEDICINE. UNH-ERSITY OF MARYLAND
John F. Cadde
served as resident in public health and
preventive medicine at the Johns Hopkins
School of Hygiene and Public Health, being
awarded the master of public health degree
in 1965.
In his assignment with the National
Foundation, Dr. Cadden will be active in
the administration of medical programs in-
cluding nearly seventy March of Dimes
birth defect treatment centers across the
nation.
Dr. August Daniel King, Jr. of 1202 St.
Paul Street, Baltimore, Md., has been
recently certified by the American Board
of Surgery. Dr. King has opened his office
for the practice of general surgery at 1202
St. Paul Street and at 204 E. Joppa Road
in Towson, Md.
CLASS OF 1960
Dr. Michael J. Fellner of 562 First avenue.
New York City, was recently certified as a
specialist in dermatology by the American
Board of Dermatology at the New York
University School of Medicine.
Dr. Morton E. Smith has been recently
named Instructor in Ophthalmology in the
Department of Ophthalmology of the Wash-
ington University School of Medicine in
St. Louis. Dr. Smith recently completed a
year as Chief Resident and as National
Institute of Neurologic Diseases and Blind-
ness Fellow in Ophthalmology, the fellow-
ship being served at the Washington Uni-
versity School of Medicine.
During the calendar year of 1964, Dr.
Smith served as Fellow in Ophthalmic Path-
ology at the Armed Forces Institute of Path-
ology in Washington, D. C. His present
duties include supervision of the Ophthalmic
Pathology Laboratory at the Washington
University School of Medicine.
CLASS OF 1961
Dr. Robert A. Fink, having completed a
residency in neurological surgery at the Uni-
versity of Chicago, has been appointed
Fellow in Neurosurgery at the Donner Radi
ation Laboratory, University of California in
Berkeley.
Dr. Larry G. Tilley has announced the
opening of his office for the practice ot
medicine and pediatrics in the Oakleigh
Professional Building. 1713 Taylor Avenue
Baltimore, Md.
CLASS OF 1962
Dr. Harvey S. Feuerman has announcet
the opening of his office in association wtil
Dr. A. A. Silver at the Temple Garden
Apartment 2601 Madison Avenue, Balti
more, Maryland. Dr. Feuerman will limi
his practice to diabetes mellitus and in
ternal medicine.
Dr. Ronald L. Klimes has assumed hi
duties as the new Medical Director of th
Pleasant Acres Home and Hospital. Di
Klimes succeeds Dr. Margaret E. Croftoi
who resigned. Dr. Klimes, a native of Bait
more, said he decided to move to York aftc
he served his internship at the York Hospitu
He received his undergraduate training :
the Johns Hopkins University and h
medical degree was obtained at the Un
versify of Maryland.
CLASS OF 1963
Dr. Thomas V. Inglesby is current
stationed at the United States Naval Hospit
at Bethesda, Md.
Dr. Richard B. Kennan is currently ser
ing as a flight surgeon with the U. S. Na\
Dr. Kennan may be reached at 265 Beei
Street. Laurel, South Carolina.
Vol. .ii. No
MARYLAND ROOWl
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