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Full text of "Medical alumni bulletin [serial]"

jCI 



Dean's 
Page 



During a recent lunch with 
medical student leaders, they 
described several programs 
they are developing to 
improve the delivery of health care to 
North Carolina's rapidly growing Latino 
population. I am proud that our students 
are continuing our school's tradition ot 
creating new programs to meet communi- 
ty needs. 1 asked Dr. Cheryl McCartney. 
Executive Associate Dean lor Medical 
Education and Dr. Georgette Dent, Asso- 
ciate Dean for Student Affairs, who 
mentor and support these leaders, to 
describe the student initiatives below. 



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In the past 3,'i years. Latinos have 
become the kirgest immigrant group to the 
Lhiited States: in North Carolina, the 
Latino population increased 94.7 percent 
during the 199()s. Although our state's 
Latinos have diversified their employ- 
ment from rural farm work to jobs in 
urban construction and hospitality, this 
population remains in the ranks of low 
wage earners who face language and 
cultural barriers to our state's health care 
system. Four medical student organiza- 
tions are addressing these issues: Spanish- 
speakers Assisting Latinos Student 
Association (SALSA), the Student Health 
Action Committee (SHAC), Prevention 
in ACTion (PACT) and the International 
Health Forum (IHF). 

SALSA was organized in 1997 by 
three medical students: Marchi Lopez- 
Linus ('99). Romulo Colindres (MS4) and 
Suzanne Strandhoy ('99). The initial 20 
members provided Spanish-language 
interpreter services to the maternity and 
well-child clinics at the Chatham Countv 



Health Department in Pittsboro and our 
local student-run SHAC clinic. SALSA's 
current 80 members also serve the Wake 
County Health Department's clinics 
in Zebulon and Fuquay-Varina. UNC 
Hospitals and the SHAC health-care 
booth at the annual fair, hi Fiesta del 
Pueblo. Dr. Alan Cross (adolescent medi- 
cine) is the faculty adviser for SALSA and 
this year's co-coordinators are Vaishali 
Gupta (MS2) and Keith Kocher(MS2). 

The SHAC Clinic, located in 
Carrboro, is the oldest student-run, free 
health care clinic for indigent patients in the 
United States. SHAC's patients now 
include a significant number of Latinos. 
SHAC co-coordinators this year are David 
Yale ( MS2) and Eric Wolak ( Nursing '(K)). 
The faculty adviser is Dr. Adam Goldstein 
(family medicine). 

The IHF discusses international 
health issues and promotes opportunities 
for medical students to study abroad. 
Recently, interest in research and service 
projects in Spanish-speaking countries 
resulted in students traveling to Costa 
Rica. Honduras, Bolivia and Mexico. 
Funded by our school's foreign fellow- 
ship grant or by loans, students have 
improved their Spanish language skills 
while conducting supervised projects. 
This year's IHF co-presidents are Todd 
DeVries(MS2), Matthew Foster (MS2) 
and Alan Schulman (MS2). Caroline 
Stuck, deputy director of the Office of 
International Affairs, is the IHF faculty 
sponsor. 

PACT students focused on migrant 
health issues this fall. With support from 
the UNC Program on Prevention and the 
Wake County Health Department, 
students were on the front lines of preven- 
tion in the free clinics for these Latino 
workers. Rachel Reisner and Miriah 
Teeter (both MS2, PACT co-presidents) 
organized groups that prepared culturally 
sensitive, Spanish language curricula about 
prevalent health problems of the communi- 
ty such as diabetes, hypertension, green 
tobacco illness, sun exposure and dehy- 
dration, pact's faculty adviser is Amy 
Ward. Program on Prevention co-direc- 
tors are Drs. Russ Harris and Linda 
Kinsinger (internal medicine). 

Medical student enthusiasm for 
improving Spanish fluency has galva- 
nized co-presidents of our second-year 




class. Heather Crou.se and Rebecca Sands, 
to coordinate the development of a 
medical Spanish course for intermediate 
speakers. Internist and co-director of 
Introduction to Clinical Medicine, 
Dr. Marco Aleman, will direct this course, 
emphasizing the language skills needed to 
interview and examine patients. Associate 
University Provost Ned Brooks, who has 
supported the health affairs interdiscipli- 
nary Spanish course. La Charla. has fund- 
ed the initial development of the course, 
and Dean Houpt will continue 
the funding. 

Students discussed the creation of 
a special clinical track for those who want to 
develop their Spanish skills and cultural 
competency. Students could choose to 
complete required clinical course work in 
selected communities with a significant 
Sp;uiish-speaking population. 



Medical Alumni 
Association Officers 

President 

Gordon B. LeGraiui. MD "65 

Riilcl,i;li 

President-Klect 

Paul E. Viser. MD 84 
Cliiiron 

Vice President 

Thomas J. Kooiit/. MD 66 

\\'iii.\t(iihSii/ciii 

Secretar\ 

Ralph L. Wall Jr.. MD"7X 

WlnsldihSiili'Di 

Treasurer 

William .M. Hemdon. Jr.. MD "XI 

Chaiionc 



Editorial Staff 

John W. Stokes 

\hc President. Public Affairs & 

Markctiiv^ 

Debra Pierce 

MciiKf^iii'^ F.diuir 

Leslie F. Lang. Melissa Matson. Karen 
Slinnetord. L\nn Woolen 

Cdiurihiiiin'j. \\ riuis 

Jon Roltel (pi:. I I ) 
Bill Reaves (pg. 12) 
Slarlyn Comhs (pgs. 21. 22 1 
Don MacKen/ie (pg. 22) 
Pluiid'^niphcrs 

The Mediial Alumni liiillciin is published lour nines 
annually by ihe LNCrhapel Hill Medical .Alumni 
Association. Chapel Hill. NC 27.^ 14 Postage is paid 
by Ihe non-profit asstKiation through L'.S. Postal 
Permit No. 24. Address correspondence to the editor. 
OfTice of Medical Center Public AITain.. .School ol 
Medicine. CB#7WK). rjniversily of North Carolina. 
Chapel Hill. NC27';i4. 



Medical Alumni 

BULLETIN 

School of Medicine, I niversity of North Carolina at Chapel Hill 



Contents 


Features 

MissniiiariL's lit the Medical Type 




->, 


Building .An Acadoniic Medical Center 




....6 

....<S 


.SiitgeiA StLidents Create Hugh Willianison Society 

Cuban Pediatrics Patient Takes International .-Xdx enlure 

At 97. He Stares at Scars So Others May Breathe 

LINC Stud\ Points to Chroniosonie Site ot .-Xutisin Gene 

Alumni Protlle: Frank Huyler. MD '9.^ 




....9 
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..14 

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Alumni Weekend 




Departments 


...Inside Fn)nt C 


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Facultv Notes 




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Piesiclenl's Letter 


Inside Back C 


CMI-:/Alumni Calendar 


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News 
Briefs 



UNC now home to new 
nutrition research center 

To help reduce the staggering toll 
of unnecessary illness and premature death 
associated u ith chronic disease and to 
understand better the links between such 
diseases and nutrition, the National Institutes 
of Health chose L'NC as home of the nation's 
newest Clinical Nutrition Research Linit. 

"In the next five years, we'll receive S4.7 
million from NIH to establish and operate 
this unit." said Steven Zeisel, MD. PhD. 
chair of nutrition for the schools of medicine 
and public health and director of the new 
center 

"Our central goals will be to enhance the 
speed at which new laboratory discoveries 
are used in population-based and clinical 
research, to make suic that the education of 
health professionals includes nutrition and 
to help people learn how they can improve 
their diets to stay healthy." he said. 

UNC will be one of only seven such units 
in the United States. Others are at Harvard. 
Washington University in St. Louis and the 
universities of Chicago. Washington at 
Seattle. Southern Alabama and Colorado at 
Denver. 

For more infonuanon. sec hitp.Hwww. 
iiiu .cilii ncus neasM-'rviuniv zeisel^ KU.'fy 
y.hliii. 

Program on Health Outcomes 
receives $2 million grant 

UNC's Program on Health Outcomes 
w ill receive nearly $2 million from the 
federal government to create a Center for 
Education and Research on Therapeutics 
that v\ ill develop innovative education and 
research efforts focusing on new and exist- 
ing drugs and devices used in pediatric care. 

The new center, is funded by a three-year. 
$1.98 million grant from the Agency for 
Health Care Policy and Research 
(AHCPR). part of the U.S. Department of 
Health and Human Sen. ices. 

Carolina's newest research addition is 
one of four centers for education and 
research on therapeutics (CERT) created 
nationw ide to boost the positive impact on 



patient care of medical products — drugs, 
biologies and medical devices — to reduce 
the human and economic toll of inappropri- 
ate use. 

flNC researchers will focus on impros - 
ing the health of children and adolescents. 
Potential research areas include therapeutic 
drug monitoring in HIV-infected children, 
drug metabolism, vitamin D-deficient rick- 
ets, asthma care, attention deficit-hyperac- 
tivity disorder and adverse dnig reactions. 

For more information, see liltp:/ nruw. 
itih .ediil news! newsserrl unir^ sphi)92W^ . 
him. 

Adolescent mothers to 
benefit from new grant 

UNC's schools of medicine and public 
health have received more than S 1 .5 million 
from the Robert Wood Johnson Foundation 
to support nurse home-visiting efforts that 
help first-time, low -income adolescent 
mothers and their new boms. 

The funds are part of a three-year. 
SlO-million grant awarded to the Children's 
Hospital .Association of Denver to support 
such efforts in 40 communities nationwide. 
The grant will help establish a national 
center for the home-nursing program at the 
University of Colorado and a regional 
center to be managed by the UNC School of 
Public Health's North Carolina Institute 
for Public Health. In the next three years, 
the centers will train nurses and provide 
support to implement a network of 
programs in the communities. 

The program provides in-home services 
during pregnancy and the first two years of 
a child's life. During weekly or biweekly 
\ isits. nurses help expectant and new 
mothers improve their knowledge of child 
health and development, build parenting 
skills and guide personal decision-making 
about employment, substance abuse and 
future pregnancies. 

"The nurse home-visiting services 
promote health in all areas: physical, 
mental, emotional and social." said 
Terrence Kenan, special program consul- 
tant at the Robert Wood Johnson Founda- 
tion. "This program provides young. 



low -income mothers v\ ith crucial instruc- 
tion, care and support that they might not 
otherw ise receive." 

New procedure offers 
alternative for nasal surgery 

An ear, nose and throat doctor at UNC is 
using a new technology already proven 
successful in treating snoring to provide a 
less expensive, relatively pain-free alterna- 
tive to traditional nasal obstruction surgery. 

"This nonsurgical procedure, called 
somnoplasty. could change how we're 
doing things," said Wendell Yarbrough, 
MD, assistant professor of otolaryngology, 
w ho divides his time between head and 
neck cancer research and clinical duties. 
"The technology was first approved for 
treating snoring, which is treatment of the 
palate. It's exciting that another innovative 
use of the technology has been approved." 

SomnoplastN delivers radio frequency 
energ\ through a needle, w hich. in the 
treatment for snoring, is put underneath 
the lining of the mouth. 

"It creates a scar that, as it fonns. tightens 
up the palate and decreases the volume and 
intensity of snoring," Yarbrough said. "The 
procedure is relatively pain-free — patients 
might need to take some Motrin or Tylenol 
immediately but narcotics for seven to 10 
days are unnecessary. It's also more conve- 
nient and less expensive because it can be 
done in a physician's office and the patient 
can be back at work the next day. 

For the complete story, see littpillwww. 
unc.edu!ne\\slne\vssenircsearchlyarhr(ni3 
lOOIW.Iitm. 

Correction 

In the Summer 1999 Medical Alumni 
Bulletin, we printed a New s Brief titled 
"Womack Society Honors Plastic Surgeon." 
We inadvertently failed to credit Carl R. 
Hartrampf Jr.. MD, with commissioning, 
funding and donating the portrait of Erie E. 
Peacock Jr.. MD. JD. We extend our 
apologies. 



Missionaries of the Medical Type 



By Melissa Matson 

F.dihtr' s note: Manx i SC plnsiciaiis 
inivcU'd (.ihroiid this past xcui. This artnlc 
is not iiucndcd to hcamipirhcnsivc- 

When most people think ot missions. 
the\ think of something religious 
in nature. But that's only p;ul of the 
definition. Webster defines a mission as 
"a sending out to perfomi a special sen ice." 
.And that special ser\ ice can be anything — 
political. scK'ial. medical orothen\ ise. 

Here at UNC. we ha\e a hislor\ of 
leaching the next generation i)f doctors. We 
also ha\ e a histor\ of sharing our expertise 
w ith other doctors around the state and the 
country. For some UNC physicians, that 
mission translates into traveling to less 
tortunate countries to train local physicians 
and pro\ ide medical services to local 
people. 

Follow ing are the sti>ries of a few \\ ho 
ha\ e gone on medical missions this y ear 

Helping children in Venezuela 

This September. James Fletcher. 
MBBS. clinical associate professor of 
anesthesiolog\. and Robert Valle\'. MD. 
associate professor of anesthesiology and 
pediatrics, went to Maracaibo. Venezuela 
with Rotaplast International'. They were 
there 1 2 days. 

On the first day. the team of fi\'e 
surgeons and six anesthesiologists screened 
ISO pediatric patients prior to surgery. 
Then, during the next six days, the team 
operated on 16.^ patients to repair cleft lips, 
cleft palates or both. Fletcher and Valley 
each pro\ ided anesthetic ser\'ices to five or 
six children per da\. 

As in the case of most medical mis- 
sions, thev brought their ow n equipment 
and supplies along w ith them, then set up 
tor clinic and surgery in the local children's 
hospital. Fletcher said of the facilities. "The 
hospital lackeil much of the equipment that 
we see around American hospitals, but our 
hosts still had a good infrastructure for us lo 
plug into. I learned sou can achiese a whole 
lot w ith few resources." 

ValleN agreed. 'It was much easier 
than 1 expected to maintain an excellent 
standard of care in a less-advantageil health 
care facility." he said. "All it took was a 
little ingenuity and a great team." 



"The whole trip was intense." said 
Fletcher "To see children traiisfomied from 
social outcasts because of facial defoniiities 
to socially acceptable was ama/ing. The 
parents were indescribably happy to ha\e 
their children's appearances impro\ed." 

Both Fletcher and \alle\ plan lo go on 
future trips. 

'■The mission of RotupUist Inlcinatioii- 
al. Inc. is to provide free rt'consinictivc 
siiii;cr\for indiiicni children with cleft lip. 
cleft palate and other facial deformities. 
\ ohintecr doctors and nnr.ses are matched 
with Rotary volunteers in host countries, 
who take care of paperwork, find patients, 
anil provide operaiin:.^ rooms and housin<^ 
for the team. 

Fixing hearts in Nicaragua 

You'd never know from the beautiful 
Pacific coast that Nicaragua has been 
through tw o wars in 20 years. But it has. and 
those w ars have taken a toll on the country's 
infrastructure. 

Since 1986. a group of North Carolina 
surgeons have sought to help remedy that 
by traveling to the country on medical 
missions. They've done so through 
"Nicaragua: A Project Leon." a program 
started by John Paar. Ml), a Raleigh 
cardiologist. 

William Sulli\';in. MD. a general 
surgeon at Wake Medical Center. AHEC 
appointee, and team member, presented his 
most recent trip to Leon. Nicaragua during 
Surgery Grand Rounds last fall. "Our trips 
are a little different from some in that we go 
primarily as collaborators." said Sullivan. 
".Nicaragua has no lack of doctors. What 
they lack are resources. So we go to assist 
and exchange ideas." 

Built in U)79. Leon's public hospital 
has 2.^0 beds, including an eight-bed ICLI. 
Despite its si/e. the hospital can care tor a 
relatively small number of patients because 
ot limited supplies. "There's a lack of nurs- 
ing help, equipment, drugs, and things such 
as sutures and gauze." Sullivan saiil. "lis 
humbling lo realize how much we have and 
lake for granted here in the U.S." 

In recent years. Sullivan and his leani 
have shipped surgical books, anesihelic 
machines, lelal momlors. surgical cauleries. 
pulse oximeters and surgical instruments to 
the hospital in Leon. 

When asked whv he uoes on these 



trips. Sullivan said. ">'our slicccss as a 
surgeon depends on the number ot patients 
who leave the hospital better than w hen 
they came. To help the people of Leon and 
see their improvemeni is an honor. " 

Repairing urology problems in 
Belize 

In Januarv 1999. a pediatrician from 
Goldsboro called Tim Bukovv ski. MD. 
medical director for L'NC's pediatric urolo- 
gy service. "1 have a child w ith a urethral 
obstruction that I'd like vou to see." saiil the 
doctor. "The onlv problem is ihal he is in 
Belize." 

Bukovv ski agreed to evaluate the chikl. 
He decided that rather than have the child 
come to the L'nited States, it would be easier 
on everyone if he w ent there. He w as soon 
contacted b\ Egbert Grinage. MD. a pedia- 
trician in Belize and tounder ot Friends of 
Pediatrics, a grass roots organization that 
brings specialists to Belize through the sup- 
port of the Belize Citv Rotary Club and 
local companies. 

Bukowski went on his lirsi trip last 
.April. He spent three days ihcie. during 
w hich time he saw 40 patients and operated 
on 10. When he went again in September, 
he saw SO patients aiul operated on 12. 
using main of the cases lo leach ihe local 
dtKlors. 




Tmiliukowski.MD 



The Belize medical s> stem is state run. 
"There are tlve public hospitals and a smat- 
tering of private medical practices like in 
Britain." said Bukowski. "The problem 
there is technology. I can help by bringing 
the technology to them." 

What did Bukowski take aua\ 
from the trip? "I guess the biggcsi 
thing I tix)k away wa.s ho\\ crucial il is 
that the host country need and w am 
\our help." Bukow ski said. ""These 
types of missions don't v\ork unless 
the country has some sort of system to 
bring specialists in luid gel patients to 
the facilities." 

Bukowski said that the real 
hero in the story is Dr. Grinage. the 
Belizian pediatrician, who has 
worked through the years to better 
medical care in his country. ""He 
really is a remarkable man." said 
Bukowski. ""His next goal is to build 
a pediatric intensi\e care unit." 



experienced life outside the de\eloped 
world, and second, il would be a chance for 
some great surgical experience." 

He traveled with then-UNC fellow Jeff 
Wilkerson. MD. a specialist in urogynecol- 




ln!/hin\ ( 'uj^plcilLhilili 



nicr. KiJLihc. Kenya 



Making Indian women healthier 

Gil Reid. MD "93. chief resident in 
OB/Gyn. spent 1 days in Jamkhed. India, a 
\ illage 450 miles east of Bombay. It was 
there that he w itnessed and participated in a 
successful rural health project. 

For his third-year residencs project. 
Reid had a choice of research or a clinical 
experience away from campus. He chose 
the latter. "I decided to go that route for two 
reasons." said Reid. '"First. I had never 



ogy. to the Comprehensixo Rinal Health 
Project in Jamkhed. Established by \\\o 
Indian physicians trained at John Hopkins 
University, the program trains las people in 
outlying villages to provide simple medical 
care such as vaccinations, prenatal care, and 
nmniloring vital signs. 

On their first day. Reid and Wilkerson 
held clinic for 52 women. "We set up two 
exam rooms. There were no beds with 
stirrups, so we used regular tables for the 
exams." Reid said. 




During their 10-da\ stay, they 
performed 12 major urogynecological 
surgeries, most of them vaginal vault 
prolapse repairs. "The degree of prolapse 
w as amazing.'" said Reid. ""It's due to poor 
nutrition and the high number of 
children each woman bears." 

Of the rural health project. 
Reid said. ""The doctors are able to 
pro\ ide medical care that helps the 
people physically, but the biggest 
impact is social. B\ training women 
in the lowest castes to be lay health 
workers, they have assured them a 
place in their \illages." 

Fixing facial deformities in 
Africa 

This summer. Brian Jewett. 
MD. chief ENT resident, traveled to 
Kijabe. Kenya with World Medical 
Mission.* He was joined by three 
other .\merican surgeons, a family 
practitioner and an anesthesiologist on the 
two-week trip. 

For many Kenyans, medical care is 
difficult to come by. ""Kenya has a shortage 
of medical providers, and most of them con- 
centrate their efforts in Nairobi." said Jevi - 
eti. "Many people in outlying areas cannot 
get to Nairobi for medical care. So when 
specialists come to Kijabe. they go there. " 

The team spent their time at Bethan\ 
Crippled Children's Center, a .^6-bed reha- 
bilitation center. While there. Jewett and the 
others operated on 60 children w ith cleft lip 
or palate. They also saw 60 pediatric 
patients per day for other ENT problems, 
such as thyroid disorders. 

""I was impressed by the dedication of 
the OR staff." Jewett said. ""Some of our 
days were up to 14 hours long, but the staff 
were the first ones there and the last ones to 
lea\'e. They wanted those children to receive 
the care they so desperately needed." 

Jewett found that the Children's Center 
served not just as a rehabilitation facility but 
as a teaching hospital. ""Throughout the 
vear. British. Gemian. American and other 
specialists come to Kijabe to pro\ ide 
ser\ices." said Jewett. ""Doctors training in 
Nairobi will visit the center to learn from 
the foreign doctors." 

*U<))/(/ Medical Mission is an offshoot of 
Samaritan's Purse, a Ininianitarian organi- 
zation run hy Franklin Graham, .um of Billy 
Graham. 



Gil Reul. MD. in .Jamkhed. India 



International Health Program Receives 
$88 Million Federal Contract 



An international health program at 
UNC recently won S88 million from the 
federal government, making it the largest 
contract aw arded to the university in its 
206-year history. 

The tl\ e-\ ear cooperative agreement 
K-tween INTRAH and the U.S. Agency for 
International Development (USAID) also 
IS the largest aw arded to any of the I 6 
campuses in the UNC system, said 
Dr. Richard W. Linton, associate vice 
president for research and director of 
sponsored programs at UNC General 
.Administration. 

The S8S million w ill allow the program 
to implement L'S.AlD's new Primar\ 
Providers Pertomiance lmpro\ement in Re- 
productive Health Project (PRIME II). 
which is designed to create sustainable, 
national s\ stems for training and education 
in family planning and reproducti\e health 
in developing countries. 

PRIME II aims to improve the work 
performance of primary health-care 
providers in Africa. Asia. Latin America, 
the Caribbean, the Near East and the new 
mdependent states of eastern Europe and 
the former So\ iet Union, said Dn James W. 
Lea. director of INTRAH and the UNC 
School of Medicine's Office of International 
Affairs. 

Since its start in 1979. INTRAH and its 
worldw ide efforts have followed Carolina's 
long-standing tradition of extending its edu- 
cational and sen.ice capabilities beyond the 
physical boundaries of the campus. Lea 
said. He compared INTRAH with the 
successful N.C. Area Health Education 
Program, which improves the supply, distri- 
bution and quality of primary hoallh-carc 
pr(>\ iders across the state. 

"Our program crosses traditional 
departmental lines and allows us to appls 
the university's enonnous expertise directiv 
upon improving the health of mothers 
and infants — a crucial area of concern for 
people in North Carolina and arouiHJ the 



world." Lea said. "That's what we'll do 
even more vigorously, thanks to this 
renewed financial support." 

With this latest SSS-niillioii coopera- 
ti\e agreement. INTR.AH has recei\ed 
more than S2()0 million from L'S.AID since 
1979. INTRAH has helped local health- 
care workers offer men and women 
improved access to quality family-planning 
services, prevented unw anted or unplanned 
pregnancies and campaigned against HIV 
and other sexually transmitted diseases. 

"We strengthen the performance of 
proN'iders as the\ sirise to inipro\e famiK 



^ ^ Our program crosses 

traditional departmental 

lines and allows us to 

apply the university's 

enormous expertise 

directly upon 

improving the health of 

mothers and infants... 



planning and reproductive health services in 
their communities." Lea said. "We do our 
work through training and other innovative 
learning methods, adapting cutting-edge 
lechnologN and collaborating closely w ith 
host couniiA' colleagues to suppoil national 
reproducti\e health goals and priorities." 

The PR 1. VIE ifproiect brings together 
organizations expericnceil in miernalioiial 
health and de\elopment. They incluile Ipas. 
a nonprofit reproducti\e health group basetl 
m Chapel Hill; .WSC Internalional of New 



York; Abt Associates of Cambridge. Mass.; 
Training Resources Group Inc.. of .Alexan- 
dria. Va.; and the Program tor .Appropriate 
Technology in Health in Seattle. The .Amer- 
ican College of Nurse Midw i\es and Save 
the Children Federation also will work with 
the project. INTR.AH has offices in Togo. 
India. Kenya and the Dominican Republic. 



Building an Academic Medical Center 



By Karen Stinneford 

While it might surprise someone 
navigating around the dump 
trucks, cement mixers, pylons 
and construction fences that ha\e come 
to symbolize "Manning Drive" on South 
Campus, the truth is 
the UNC School of 
Medicine still lacks 
sufficient laboratories, 
offices and class- 
rooms needed to sup- 
port, nurture and grow 
world-class research, 
clinical and teaching 
programs. •■■m' 

Given the univer- „ tum 
sily"s many financial 
needs — such as suffi- 
cient faculty salarv 
money to recruit and 
retain the best and 
brightest teachers and 
researchers and pro- 
vide funds to establish 
their laboratories — a 
"building" can seem 
insignificant, at best. That is, until you try to 
fiiitl the phvsical space on campus to house 
those ne\\ 1_\ hired faculty. 

At the most fundamental level, it 
is the physical buildings of UNC that per- 
mit its faculty, staff and students to fulfill 
the university's missions of teaching, ser- 
vice and research. 

Here's a look at some of the School 
of Medicine's cun-ent and planned capital 
building projects: 

Neuroscience.s Research 
Building 

This building will replace the fonner 
Biological Sciences Research Center, 
which was torn down to make room for 
the new N.C. Women's Hospital next to 
the N.C. Neurosciences Hospital. 

"When the BSRC went offline to 
make way for the new hospital, the med- 
ical school incurred a significant loss of 
space," explained David Perry, executive 
associate dean for administration. "The 



new Neurosciences Research Building 
barely gets us back to where we were 
before in terms of research space, so we 
are greatly looking forward to its coming 
online." 

The eight-story building will cost 
about $30 million, and school officials 




Nfiiidscicihcs Rfscanli Ruildiivj. 

plan to start moving facultv into the 
building sometime this summer. It is 
located on Columbia Street, behind the 
Thurston-Bowles Building. 

The building's "anchor tenant" 
will be the UNC Neuroscience 
Center, directed by William Snider. MD. 
"77. The building also will provide 
permanent space for the neurobiology 
curriculum, additional space for several 
neu faculty members in basic neuro- 
science. and faculty "incubator"" space for 
the development of clinical neuroscien- 
tists with direct research ties to basic 
scientists in the center. 

Two entire floors of the building vvill 
be devoted to laboratory animal inedi- 
cine. one of them specifically to house an 
Animal Models Center (funded in part by 
the Keck Foundation) for UNC"s 
"mousers."" researchers who specialize in 
the study of mouse genomics. Oliver 
Smithies. DPhil. Nobuyo Maeda. PhD. 
and Terry Van Dyke. PhD. are just some 



of the faculty members steering UNC"s 
internationally renowned mouse 
genomics program. 

Another floor will house the build- 
ings administrative and mechanical 
tunctions. and school administrators cur- 
rently are considering how to best parcel 
out the remaining 
three floors of 
undesignated 
research space. 

The Medical 
Biomolecular 
Research 
Building 

This lOO.OOO- 
square-foot. $64- 
million facilitv 
could house 60 to 
80 principal inves- 
tigators - presuni- 
ing the necessary 
funding becomes 
axailable to build it. 
The building 
was approved by 
the N.C. General Assembly with the 
understanding that the School of Medi- 
cine would finance half the cost through 
revenue bonds. The uni\ersity is expect- 
ed to issue the revenue bonds for the 
school's portion of the project sometime 
early this year. About S7 million of the 
state's share of the project has been 
appropriated by the legislature thus far. 
allowing the school to break ground and 
begin v\orking on utilities and the foun- 
dation. 

Unfortunately, the N.C. General 
Assembly made its agreement with UNC 
before Hurricane Floyd devastated eastem 
North Carolina. 

"We are. for all practical purposes, 
out of research space, so this building is 
critically important to UNC's ability to 
seize opportunities for growth in research 
funding by the federal government and 
private inclustry."" Perry said. "And we're 
in a great position to do so because of the 
caliber of our faculty and their demon- 
strated ability to gamer our fair share of 



those additional resources. Without that 
building, however, our ability to do that 
is seriously constrained. 

"Having said that, though, whii can 
say that a research building is more 
important than helping the residents 
down east rebuild their li\es. their homes 
and their li\ elihoods .' .And that's the 
dilemma facing the General .Assemble" 
Perr\ added. 

Plans tor the Medical Biomolecular 
Research Building include two auditori- 
ums, one that would seat about 300 peo- 
ple, the other 300 people. The auditorium 
space also is critical. Perry said. 

"There realh is no place decent 
south ot Manning Drive that you could 
call an auditorium." Perry said. "The lack 
of an attracti\e multi-media auditorium 
has been problematic for people tr\ ing to 
arrange lectures by distinguished visiting 
scholars and other e\ents we want to 
encourage faculty, staff, students and the 
public to attend." 

If all facets of the funding package 
become available on time, the building 
could be completed by mid-20()2. Perry 
said. 

Faculty Office Building 

Plans put the Faculty Office Building 
on Mason Fann Road next to Odom Village 
and behind the medical center's parking 
decks comenient to the hospitals and the 
Ambulator) Care Center. The fne-story. 
S3?-million building would provide facul- 
ty, post-doctoral fellows and support staff 
with about 61.000 square feet of badly 
needed office space. 

"The building predominantly would 
help our clinical departments by housing 
faculty and staff who now. often times, 
are housed in cramped, converted 
research laboratories and other sites," 
Perry said, adding that the building 
would accommodate faculty and staff 
currentis working in \arious trailers and 
in the antiquated wings B, C. D. F and F 
of the medical school. 

"Those wings were created nearly .30 
years ago to be dorm rooins, not offices, 
yet we have them crammed full of 



people." Perry said. "The structures aic 
mechanically frail, not readily accessible 
to the handicapped and located on v\hat 
is "prime real estate' for future hospital 
expansion, but we can't tear them down 
at this time because we have no place 
else for people to go. The advent of the 
Faculty Office Building will afford the 
school the opportunits to better house its 
\er\ protluctise faculty and staff, and in 
time to demolish the antiquated wings to 
make w a\ for future hospital expansion. " 

Medical Sciences Research 
Building 

A wholesale gut rehab and construc- 
tive re-use of this 4()-year-old structure 
which adjoins MacNider on the north end 
is the final component of the School's 
major capital program. 

""All this vintage building's infrastruc- 
ture — heating, cooling, plumbing, electri- 
cal systems — is antiquated beyond repair 
and in need of complete replacement." 
Pern. said. 



""While the building's si/e and configura- 
tion do not lend themselves to future use 
for state-of-the-art biomedical research 
purposes, the building can, when fully 
ieno\ated and restored, serve the .School 
well as teaching and academic support 
space. Our current thinking is that the 
MSRB. after reno\ation, would serve as 
the new home for the School's highly 
regarded Department of Allied Health 
Sciences, which for some time has been 
housed in substandard and insufficient 
space in the School's "w ings" buildings." 

Other renovations underway include 
a floor-by-floor updating of Brinkhous- 
BuUitt and the Mary Ellen Jones build- 
ings. Burnett-Womack and Berryhill Hall 
also need major attention. 

""One of the challenges in reiunating 
existing buildings is how to complete 
construction work at the same time you 
need facults to continue to teach and 
conduct research m those structures."' 
Perrv said. 




/•(/( iiln OII'k {■ Hialiliiii; 



The Campus Master Plan 



Ayers Saint Gross, a Baltimore architectural tlmi specializing 
in college campus planning, was hired by UNC"s Board of Trustees 
in 1998 to update the master land-use plan tor the 74()-acre 
central campus, 

A master plan is a blueprint for possible development over 
a 20- to 5()-year period. When completed, the plan will guide 
decisions about new buildings, renovations, green space, parking, 
transit and pedestrians — helping UNC prepare for future growth 
while enhancing the beauty for which the campus is so uell know n. 

The last master plan tor UNC's central campus v\as completed 
in 1991. .Since then, several developments made updating the plan 
critical: 

• A construction boom. Today, the central ciuiipiis houses more than 
l.'^O buildings, plus 29 residence halls. Fourteen capital projects 
totaling $50 million were completed between July 1998 and Janu- 
ary 1999. and 26 projects valued at $15,^ million now are under 
constmction. Another .'iO projects with a S279 million price tag 
are in desicn staces. 



Completion of the Chancellor's httellectual Chmate Task Force 
Report. Along with major recommendations about academic 
programs and facilities, the report stressed the importance 
of well-designed indoor and outdoor spaces to foster intellectual 
conversation. 

Enrollment growth. UNC trustees have endorsed a plan to add 
3,200 new students by 2008, The endorsement stemmed from a 
UNC system call for its campuses to address a sharp increase in 
the number of high-school students who wish to attend college in 
the next decade. 

Shortage of research space. Recent studies commissioned bv the 
UNC system and Carolina have documented an extreme academ- 
ic space crisis on the Chapel Hill campus, especially for research 
laboratories and offices. Administrators say the lack of essential 
research, graduate student office and enhanced instructional space 
threatens the university's ability to attract and retain highl\ quali- 
fied faculty. 




Medical Biomoleadar Research BuiUing 



Surgery Students Create 
Hugh Williamson Society 



The neul> tomied Hugh WiUiainson 
SoLieiN. a group for medical 
students interested in careers in 
surgers'. held its first meeting last fall. The 
society's mission is to pro\ ide educational 
and mentoring opportunities for first- and 
second-\ear medical students interested in 
surgical practices in academic medical 
centers or communit\ -based practices. 

The society was named for Hugh 
Williamson. MD. in appreciation for his 
pioneering contributions to medicine in 
North Carolina during the era of the Revo- 
lutionary War. In 1780, Williamson was 
appointed surgeon general of some 4.()0() 
North Carolina militia sent to help defend 
South Carolina and Georgia against British 
forces. 

Williamson studied medicine under 
John Hunter, who is known as the "father 
of scientific surger> '" and came to America 
after practicing on the European continent. 
Williamson ser\ed as a go-between 
for Benjamin Franklin and the leaders of 
the evolving American Revolutionary 
Committees of Safety. When the Revolu- 
tionary War broke out. he traveled to North 
Carolina, where he remained inlimateh 
connected with North Carolina troops until 
the war's conclusion. 

Follow ing the end of his career as an 
army surgeon in the field. Williamson 
became a distinguished legislator. He was 
an active delegate to the Federal Conven- 
tion and sened in the first U.S. House of 
Representatives. Along with William R. 
Davie, the founder of the University of 
North Carolina. Williamson helped choose 
the location of the university in Chapel 
Hill: he also served as one of its first 
trustees and donated money for the first 
library. 

The Hugh Williamson Society's first 
speaker was Christopher Baker. MD. 
professor of surgery. Baker shared his 
insight on surgical careers based on 
information he has gathered during his 20 
years as ;ui academic surgeon. 

David Cierber. MD. and David Ollila. 
MD. will serve as the society's faculty 
advisers. Students Ian Buchanan and John 
Meisinger will serve as co-presidents. 



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Besides offering students educational 
ami mentoring opportunities, the societs 
will select one student annually to receixe 
the Hugh Williamson. MD. Award for 
Excellence in Surgcrs. in be presentetl 
to the outstanding siiulcnl on surgical 
rotations at commencement. The winner 
will attend the annual Clinical Congress of 



the .American Ci 
supjiorl from llu 
and the ACS. 



liege of Surgeons 
department of su 



with 
rgery 



Cuban Pediatrics Patient Take 



By Lynn Woolen 

All the conditions were present to 
produce a major media stomi: Cuban 
President Fidel Castro, his political 
toe. U.S. Sen. Jesse Helms; the United 
States' controversial embargo that prevents 
medical supplies from entering the country 
and a theologically liberal congregation ot 
N.C. Baptists. 

At the eye of the media storm stood a 
7-year-old Cuban boy about whom some 
Ainericans claimed — and Cuban officials 
denied — would die from a congenital liver 
ailment if he didn't get proper medical treat- 
ment in the United States. 

The church involved. Pullen Memorial 
Baptist in Raleigh, learned about the plight of 
young Raudel Alfonso of Matanzas, Cuba, 
when one of its members, the Rev. Ned 
Walsh, a retired Baptist chaplain, visited the 
country scouting for Habitat for Humanity 
building sites. A doctor there told Walsh that 
Raudel needed medical treatment in the Unit- 
ed States because doctors couldn't properly 
treat him in Cuba. 

Moved, Walsh was even more touched 
when he learned that Raudel 's mother and 
father had lost two other children to the same 
liver ailment Raudel siilTeied. When Walsh 
returned to North Carolina, he enlisted his 
congregation to lobby the Cuban and Ameri- 
can governments to allow Raudel and his 
mother to make an emergency trip to the 
United States. 

To expedite the process. Walsh asked 
North Carolina's senior U.S. Senator. Jesse 
Helms, to intercede on the child'.s behalf. 
Helms, a longtime opponent of Fidel Castro 
and a staunch supporter of the U.S. embargo 
of Cuba, contacted U.S. Secretary of State 
Madeline Albright seeking an emergency hu- 
manitarian visa for Raudel and his mother, 
klalmis Alfonso G;u-cia. 

Ill the meantime, organizers of Raudel's 
visit approached LINC Hospitals and asked 
officials to treat Raudel. The hospital agreed. 
After Cuba showed little sign of letting 
mother and son leave. Illinois Gov. George 
Rvan. who was in the country on official 



business, heard of the problem and stepped 
in. Ryan negotiated the pair's release and 
accompanied them to Chicago before send- 
ing them on to North Carolina. 

Raudel and his mother arrived at 
Raleigh-Durham International Airport Oct. 
2^) and were taken directly to LINC Hospitals. 
Having experienced a media maelstrom in 
Chicago, the two braced themselves for 
reporters and photographers awaiting them at 
the airport and hospital, where they briefly 
posed for photographs. Media including 



^ • After the veins are 
clotted oif — through 

a procedure called 

sclerotherapy that UNC 

pediatric gastroenterologists 

have done for more than 1 5 

years — we believe Raudel 

can return to Cuba with 

this problem behind him 

at last, Rhoads said. 



CNN. ABC News, USA Today, the Associat- 
ed Press, The Chicago Tribune. The News 
and Observer of Raleigh. The Hcraid-Siin of 
Durham and local TV stations followed 
Raudel's Journey. 

A L'NC pediatric and surgical team led 
by Marc Rhoads. MD. professor of pediatric 
gastroenterology, found that Raudel suffered 
from portal vein thrombosis w ith extensive 
collateral circulation. This meant Raudel had 
several small high-pressure veins leading 
into his liver instead of one "high-tlow" vein. 



and as a result, blood backed up into his 
esophagus. The condition often occurs as a 
result of an innammation of the umbilical 
vein during the perinatal period — a medical 
treatment the youngster had received as a 
newborn. 

A lengthy diagnostic prcKCss to help deter- 
mine the best course of treatment ensued. 

"He got a really good looking over by 
many of us." said Rhoads. "All during his first 
week here. UNC doctors contemplated if 
surgery could be done to "bypass' his clotted 
portal vein and decompress his large 
esophageal varices — the veins which bled 
w hen he was in Cuba." 

"During an angiography, we learned that 
Raudel had de\ eloped a spontaneous shunt. 
Thus, he already had a large, naturally devel- 
oped left spleno-renal shunt, as well as exten- 
sive collateral veins going into the liver, 
which made the surgical creation of a spleras- 
renal shunt unnecessary." 

UNC physicians determined that the 
best course of treatment was a series of 
sequential procedures rather than full-blown 
surgery. The relatively minor treatment, 
called endoscopy sclerotherapy, involves 
endoscopy and injecting Raudel's four large 
veins in the low er esophagus to clot them. 

"After the veins are clotted oft^ through 
a procedure called sclerotherapy that UNC 
pediatric gastroenterologists have done for 
more than 15 years — we belie\e Raudel can 
return to Cuba with this problem behind him 
at last." Rhoads said. "There will be a small 
chance of re-bleeding, but the risk of massive 
hemorrhage w ill be very low." 

Raudel underwent his first procedure 
Nov. 8. stayed overnight and was discharged. 
He and his mother stayed w ith members 
from Pullen Memorial Baptist before return- 
ing to UNC Hospitals two weeks later for 
foUow -up esophageal sclerotherapy. In early 
December. Raudel and his mother returned to 
Cuba, where he might have to undergo the 
procedure one or two more times, Rhoads 
said. 

"But he's looking fine." Rhoads said. 
"He's not having any symptoms at all. And 
he's now at lower risk of bleeding again." 



10 



itemational Adventure To UNC 




Kiiiulcl MIdiisn and his nwrhfr urnviii'^ <// I \( ' llmpiuil}, 



At 97, He Stares at Scars 
So Others May Breathe 



By Joel B. Obermayer 

Rcprinti'J with pcnnisston fruni the News 
ctC)/).vc/V(7- of Raleigh 




Hcifihin liii.soiN. ML) 

On a recent weekday morning. 
Dr. Hemian Easom was in his office holding 
an X-ray of a man's chest. Leaning forward, 
he traced the faint outline of the bronchial 
passages. No scarring. He threw the film in a 
stack and pulled out the next one. 

At age 97. he's been interpreting X-rays 
for the public health department for more 
than 60 years. He has no intention of stop- 
ping alls time soon. 

"I can't imagme not doing it." Easom 
said. 

Indeed, he still does it tw ice a month. 
2(X) X-rays at a time, making him the longest 
continuously serving public health employee 
the state has e\ er had. 

Easom 's career is legendary in the state 
public health department. He started the 
state's department of occupational health in 
the 1 93()s w hen he and an engineer drove 
around North Carolina in a pickup truck. 
Back then. the\' towed an X-ray machine so 
the\ could check workers' lungs for damage 
caused b\ industrial pollutants. 

"He was a pioneer. Before Dr. Easom. 
there really wasn't much state involvement 
in (workers'! health." said Debbie Crane, 
state public health department spokes- 
woman. "And then, there's his endurance... 
He just loves w hat he does." 



Easom. a Selma native, was a pre-med 
student at the University of North Carolina at 
Chapel Hill. In the 1920s. UNC had a two- 
year graduate medical program. To finish his 
medical degree. Easom had to travel to 
.St. Louis. After that, he w orked a summer tor 
a state tuberculosis sanitarium. In 1935. he 
landed a job with the state public health 
department. 

Back then. plent\ of factories worked 
w ith asbestos. It was particularly popular to 
w ea\ e it into cloth for industrial uses. 

Also, rock quiuries and other companies 
that cut or crushed rock produced tine dust 
panicles that workers routinely breathed in. 

Few workers were aware of the health 
problems that could result. 

Easom began to address that by setting 
up the North Carolina Dusty Trades Pro- 
gram. It was the first time the state had 
become actively invohed in an occupational 
health issue. 

Easom and an engineer set out to visit 
nearly every employer in the state w ho 
worked w ith asbestos or finely ground rock. 
Later on. the two men did another set of long 
road trips taking X-rays of workers' chests. 

What they found was a public health 
menace. One of the places they visited was a 
mine in the Sandhills where workers were 
packing talc powder the consistency of fine 
flour: it was used as an additive in paint and 
for batteries. Looking at the X-rays. Easom 
found that one-third of all v\orkers there, 
young and old. had lung damage from the 
dust. 

"We were shocked. We had no idea the 
problem was that serious." Easom said. "The 
workers didn't know they were getting sick." 

One exception was a man Easom met 
who could hardl\ breathe. The man was in 
his late 20s and had been bagging talc in the 
factory for less than 10 years. He eventually 
died because of the damage to his lungs, and 
Easom and a pathologist exhumed the bod> 
to prove that the man's death was caused by 
the dust. 

That v\ as turning point. Easom said. 

He w as able to use the autopsy to show 
the company and the workers v\ hat was 
happening. TTie company abandoned the plant 
and replaced it w ith one that had much better 
dust control. Easom persuaded many other 
emplo\ ers to ch;inge their practices. a.s well. 

Easom. v\. orking with members of the 



U.S. Public Health Service, published a pair 
of research papers about w hat he had found 
w ith his X-rays. The papers eventually 
became the basis of national health policies 
I ol lowed by the Centers for Disease Control 
and Prevention and the National Institutes of 
Health. 

Pat Curan. an industrial hygiene 
engineer in the state Department of Health 
and Human Services, said he has know n 
Easom for 28 years but has rarely heard him 
talk about this accomplishment. 

"His papers were the backbone of nation- 
al health policy, but he doesn't talk about it 
except in tidbits. He's too modest." Curran 
said. "I had to hear about it from the folks at 
CDC and the National Cancer Institute." 

Easom eventually decided he wanted to 
see patients regularly. In 19-14. he took a job 
as director of a state sanitarium for tubercu- 
losis patients in Wilson. He often read .\-rays 
there looking for lung damage. 

But his hospital was as much as ware- 
house as a treatment facility. For TB. thefe 
were no effective drugs. Patients were pre- 
scribed rest and. occasionally surgery, but the 
disease often w on. Of ."iOO patients at the 
sanitarium, about 40 a year died. Easom 
would return to Raleigh on weekends to read 
chest X-rays for the Dusty Trades Program. 

Again. Ea.som w as at a historical tuming 
point. 

In the 1930s, antibiotics were intro- 
duced that could attack tuberculosis. 

"It was a huge change. The drugs made 
all the difference in the world." Ea.som said. 
"People who would have surely died, got up 
and w alked out of the hospital." 

By 19,5.5. the sanitarium was no longer 
needed and w as converted to a mental hospi- 
tal. But Easom continued to work on TB issues, 
mnning seminars and clinics for county health 
departments. He retired in 1 975. 

Of course, that couldn't keep him from 
coming to Raleigh to read his X-rays. 

Over the years, a stroke and cataract 
surgerv haven't stopped him. He has slowed 
diiwn a bit, and he doesn't walk as well as he 
did. but his evesight is still good enough to 
look at films. While he drives his Cadillac 
iiround Wilson, he now gets a ride for the trip 
totheTriiuigle. 

"I've just been incredibly lucky." 
Easom said. 'T'\e done more than I ever 
thought I'd do." 



Alumni 
Notes 



30s 



Kutus R. Little. AB '28. MI) '30. believes 
he nia\ be the only li\in2 alumnus of the 
class of 1930. He asks if there are an\ other 
sur\ i\ ing "28 or "30 alumni that lhe\ notify 
the editor of the Medical Alumni Bulletin. 
Little, now 92. remains active. He and his 
u ife have three erow n children. 



40s 



Carlton G. Watkins, MD, FAAP '40, has 

\\ ritten Bcyciul Medicine: A Ccnliiry of 
Parcntiiii; and Pediatrics in Charlotte and 
Mecklenhiin^ Counties (190.^-1999). The 
book contains the biographies of 250 pedia- 
tricians, other physicians, dentists and other 
allied health personnel. It also records the 
history of government agencies and ci\ il 
and social organizations involved in child 
welfare. The book is available from Broad- 
foot Publishing Company. 

John B. (Jraham. MD '42, has published 
his founh book since retiring in 19S.5. It is a 
cixikhook titled Southeastern Cookiiii^. 



60s 



C\ (iray. .MI) "66, plans to retire from his 
gynecology practice this winter. Gra\ 
says that his health is still good, and he 
looks forward to retirement. He was also 
recently elected president of the Southern 
Gyn/OB Societv. 

Howard D. Honusley, MI) '67, has 

returned to \ash\ ille. Tennessee, to join 
a group practice after 24 \ears in .North 
Carolina. 



70s 



National Board of Medical Examiners in 
March. Her responsibilities include organi- 
zational consulting for academic and other 
healthcare organizations. Her specialties 
include strategs consultations, leadership 
development and executive coaching. Her 
email address is CAschenbre(2)aol.com. 



80s 



Anna Bainbridge, MS '82. has been 
promoted to Director of Practice at the 
.American Ph\ sical Therapy Association 
located in Alexiuidria. Virginia. 

Lisa Koehler Burke, MD '89, is an emer- 
gency medicine physician with Peachtiee 
Emergency Asstxiates at Piedmont Hospital 
in Atlanta. She and her husband. .And\ . 
recently celebrated the birth of their son. 
Adam Marshall. 



90s 



Carol A. Aschcnbrener, MI) '71. began 
her first two-year term as chair of the 



Lnri \\. Balaban. MD '90, her husband. 

Da\ id. and stin. Michael (age 3 1/2). recently 
welcomed Joseph Daniel into their fannly. 
Balaban is a pediatrician in pri\ate practice. 

Lawrence R. Nycum. MI) '90. recently 
completed a fellow ship in g\ necological 
oncology at Walter Reed Armv Medical 
Center and the National Cancer Institute. 
He is now Division Director of Gynecologic 
Oncology at Da\ id Grant Medical Center, 
located on Travis .Air Force Base in Califor- 
nia. He holds the rank of major. Nycum also 
recentl\ was aw;irded "'Best Scientific Paper 
on Oncology"" bs the American College of 
Obstetrics Anned Forces District Meeting. 
He can be reached at Inycumrn aol.com. 

Billie ( osj-rove. MI) '92, and Chris 
( osgnive. MI) '92, are happs to he back in 
■North Carolina. The\ ha\e two chiklren. 
Spencer. .5. and Elly. 2. 



Cuiien Rutr. MI) '92. completed a fellow- 
ship in abdominal imaging at Georgetow n 
Universitv in June. He has joined Fairfax 
Radiological Consultants in Fairfax. V.A. 

Ruric (.\ndy) .Anderson. MD "93. is an 

assist;uit professor of medicine ;uid associate 
program director for the Internal Medicine 
Residency at the Medical College of 
Wisconsin in Milvvaukee. He and his wife. 
Holly, are expecting their first child in .April. 
He can be reachetl at runcC« mcw.edu. 

Laura B. Knyedi. MD '93. joined the Duke 
Eye Center facultv as an assistant clinical 
professor of ophthalmologv this August. 
Her specialty is pediatric ophthalmology 
and strabismus. She works part-time, as she 
is also the mother of 3-year-old Emily and 
14-month-old .Andrew. Her email address is 
en\ed(K)l(a mc.duke.edu. 

John Phipps, MI) '93, joined Forsyth Inter- 
nal Medicine m Jul\ 1998. His specialty is 
endocrinology. He ;ind his w ife. Melissa. ;ire 
expecting their third child in Febm;iry . 

Allison Poston, MD '95, completed her 
pediatrics residenc\' at the L ni\ersiiy 
of Kentucky in Lexington and has joined 
Pediatric and Adolescent .Associates, a 
pri\ ate practice. 

William L Smith IN. Ml) '96. has com- 
pleteil his internal metlicine resuleniA. He is 
now a cardiology fellow at Duke L'niversity 
Medical Center. He and his w ife recently 
celebrated the birth of their son. Willuim 
"Thomas" Smith \'. 

Harriet N. I)a\ is. Ml) '99, has joined 
Ghent lamiK Practice Residency Program 

in Norfolk. Virginia. She can be reached at 
tiaMshnfa fammetl.e\nis.etiu. 



13 



UNC Study Points to 
Chromosome Site of Autism Gene 



By Leslie F. Lang 

UNC researchers and collaborating 
institutions are reporting evidence 
for a possible gene on chromosome 
13 that causes autism. 

The group's report was published 
Dec. \5 in the Amciican Juunud of Mcdkol 
(ic'lhiics. 

Autism is a severe neuro-developmen- 
tal disorder marked by social and comniuni- 
cation deficits and ritualistic-repetitive 
behaviors that are detectable in e;irly child- 
hood luid continue throughout life. 

"For a long time autism was not 
\ievved as being a genetic disorder." said 
loseph Pisen. MD. professor of psychiatr\ 
and new director of the university's Mental 
Ketartlation and Developmental Disabili- 
ties Research Center. "It has a high degree 
of heritability, confirmed by twin studies 
that show a substantially higher rate in 
identical twins - so much so that heritabilits 
is more than 90 percent." 

According to Piven, a child psychia 
trist. families with an autistic child nin up 
to a 5 percent risk of having a second child 
with autism. 

"And while that percentage is not so 
high, it's substantially higher than the rate 
of autism in the general population. v\ hich 
is approximately five in lO.OOO kids" he 
said. "The data is pretty overwhelming that 
autism is strongly genetic, more so than 
schizophrenia or diabetes." 

Still, despite epidemiology evidence 
of a strong genetic influence. Piven and his 
collaborators note that the search for 
autism genes only recently has begun in 
earnest. TTie new study is one of a handful 
v\orldwide to genetically screen the DNA 
of nuclear families of autistic siblings. 

Tliis imestigation inwlved 7."^ families 
w ith at lea.st two autistic children, including 
three families having three autistic children. 
The children's ages ranged from 3 to 31 
years old. 

Findings v\ere based on an assessment 
of participants' DNA prepared from blood 
samples. The researchers spaced 416 



nucleotide markers on selected chromo- 
some regions for each individual. The 
markers helped identify those regions 
across individuals containing similar 
clusters of nucleotide sequences. .Statistical 
analysis then determined if the presence of 
these regions was significantly greater than 
chance. For a region of chromosome 13. 
the answer was yes. 

The study also highlighted several 
other possible DNA hot spots for autism 
genes, notably a region on chromosome 7. 
This latter finding confimis a 1999 report 
by an international autism research team. 

The new evidence akso converizes vs ith 



According to Piven. a child 
psychiatrist, famihes with 

an autistic child run up to a 
5 percent risk of having a 
second child with autism. 



that from another research group for a 
location in the same region of chromosome 
7 that is cunently implicated in some form 
of specific speech and language impair- 
ment, a disorder having characteristics that 
overlap that of autism. 

"We believe there must be more than 
one gene involved in autism." Piven said. 
"As in all complex behavioral disorders, 
there's no clear evidence when looking 
at family pedigrees or family trees that 
suggests a single-gene may underlie this 
disorder." 

In the second stage of the project, 
also funded by the National Institutes of 
Health, the research group will add 100 
new lamilies for a follow-up analysis. 

Participating institutions include New 
England Medical Center/Tufts University 



School of Medicine. Vanderbilt University 
School of Medicine. University of Iowa 
College of Medicine, the Johns Hopkins 
University School of Medicine and 
Harvard Universitv School of Public 
Health. 

Besides the genetics of autism. Piven 
also uses neuroimaging (with magnetic 
resonance imaging) to study structural 
differences in the brain of autistic 
individuals. He was the first researcher to 
report that brain size is greater in autistic 
persons, an enlargement that may be due 
to certain timing during the process of 
neuronal development. 

With new funding from the National 
Institute of Mental Health. Pixen's center is 
conducting a longitudinal stud) ol children 
ages IS to 3.*^ months old with autism or 
probable autism. 

""Basically, we want to look at the size 
and shape of the brain to gain insights into 
this observation of enlargement, that it may 
encompass some developmental abnonnal- 
ities in the brain during early postnatal 
development." he said. 



14 



Faculty 

Notes 



Damon Anagnos. MD. has been 
selected to participate in the 1999-2(101 
Teaching Scholars Program, a program 
designed to recognize and promote teaching 
as a critical scholarh function. 

(hristopher (". Baker. MI); Ki'\ in 
Ikhrns. Ml): Cerald Sloan. Ml): 
Anthonv A. Mexer. Ml). PhD: Amelia 
Drake. Ml): and Timothy Bukowski. MI). 
were among the t'acult) to recciN e School of 
Medicine Roster of Teaching Excellence 
a\s:u"ds. 

Margaret E. Bentley. PhD, has 
been named associate chair of the Depart- 
ment of Nutrition. She will be responsible 
for o\ ersight of academic programs in the 
department. 

Culley Carson, MD, has been named 
president ot the Urological Research Soci- 
ety. His lenii expires September 21KKI. 

Elizabeth Crais, PhD. associate pro- 
fessor of speech 
and hearing 
sciences, was 
recently named 
,1 tellow in the 
Amcncan 
Speech-Lan- 
uiiage-Hearing 
.Association. 
Crais was 

recognized for 
preparing grad- 
uate students 
and practition- 
ers to pro\ ide famil) -centered assessment 
and interxention ser\ ices. 

Thomas E. Curtis. MI), professor of 
psychiatry, v^as recognizeil as the I'M)'* 
Distinguished Alumnus at the annual 
George Ham Symposium. 

Matthew Ewend. Ml), his been 
selected to participate in the I ';9';-2()()l 
Teaching Scholars Program. He also 
received a ClinicalAIranslational Research 
Avsard from the UNC Linebeiger Compre- 
hensive Cancer Center. 




Cicii.s 




Carol A. Eord, MD, assistant profe 
sor of pediatrics 
and medicine. 
recei\ ed a four- 
> ear. S240.00() 
Generalist 
Physician Fac- 
ult\ Scholar 
Program .Aw ard 
from the Robert 
Wood Johnson 
Foundation. ^ - 

Ford will use ^^ 
the money to [oiil 

support her 
research of adolescent behavior. 

Joyce Harp. MD. assistant professor 
of nutrition, received the James Woods 
Junior Faculty .Award from the L'NC School 
of .Medicine. This aw ard recognizes one out- 
standing junior facultx member for contri- 
butions to clinic.il leaching and research. 

Karen K. 
Holfman. RN. 
MS. CIC. clin- 
ical instructor 
of infectious 
diseases and 
associate direc- 
tor of the State- 
wide Program 
for Infection 
Control and 
Epidemiology, 
was recent 1\ 
honored by the national trade magazine. 
Iiifci nun Ccnii'dl laihix. as educator of the 
\ear. 

Jack Eongenecker. PhD. clinical pro- 
lessor of nutniion. was selecleil as a fellow 
ol the American Social Nutrition 
Sciences. 

.Mice I). Ma. .MI), assisianl prolessor 
of meilicine. was awariled a Junior Faculty 
Scholar Award at the 41st annual American 
Society of Hematology (ASH) meeting held 
last December. The two-vear award 




HoJJnicin 



pro\ ides funding to scientists who ha\e 
recentl) begun their rese;irch ciu'eers ;uid lU'e 
studying blood, blood diseases, or blood- 
forming tissues. Ma is one of se\ en scien- 
tists to receive a 1999 award. 

Michael 
Mill. Ml), in 
tenin di\ ision 
chief of cardio- 
thonicic 

surgery, was 
named a mem- 
ber of the Uni- 
versity Health 
Consortium's 
CPAC Heart 
Transplant 
Clinician Coor- Mill 

ilinating Committee and CP.AC Heart Trans- 
plant Clinical Benchmarking Liaisons. 

Kim I'rich. MS\N. clinical instructor 
and case manager for the UNC Cnuiiofacial 
Center, has been appointed to serve on the 
National Advisory Dental and Craniofacial 
Research Council of the National Institutes 
of Health. 




Research 
Briefs 



Study confirms protein 
culprit in alcohol-induced 
liver disease 

For ihc first linie. UNC scientists have 
used gene-knoci\out technology to identity a 
i^ey molecular player in alcohol-induced 
liver disease. 

A report on the study appeared ni the 
journal Gastroenterology. The findings 
carry implications for targeting new treat- 
ments aimed at preventing alcohol-induced 
hepatitis and cirrhosis, 

"Having this knock-out technology will 
help us develop drug therapies lor this 
devastating disease, which affects 1 1 million 
people in the United States alone."" said 
senior study author Ronald G. Thurman. 
PhD. professor of phamiacology. 

The report pointed to tumor necrosis 
factor-alpha (TNF-alpha) as the liver injury 
culprit. This hormone-like protein is pro- 
duced in the liver and cells throughout the 
body. An immune system cytokine, it is a 
central pro-intlammatory molecule. 

The study offers the first solid proof 
that TNF-alpha figures importantly in the 
development of early liver injury as.sociated 
with long-tenii alcohol consumption. Previ- 
ously, higher levels of TNF-alpha were 
founil in alcoholics with hepatitis and labo- 
ralon. studies ha\e shown that luitibodies to 
TNF-alpha attenuated alcohol-induced liver 
in|ur\. But the cytokine"s role in the disea.se 
remained unclear. 

/■('/■ more information, see http:ll 
www.iiiH.cduhwwslnewsscn'limivlliYerlOQ 
4W.htm. 

UNC researchers look at 
effectiveness of new cancer 
drug 

A clinical study at UNC is testing 
the effectiveness of a new drug for treating 
cancers of the ovaries and endometrium, the 
lining of the uterus. 

Tlie clinical trial, sponsored by Eli Lilh 
and Co. of Indianapolis, is the only one in 
North Carolina to test this latest selective 



estrogen receptor modulator ( SERM ». 
known by its investigational number 
LY.\';.\"^81, 

Unlike traditional chemotherapy, side 
effects associated with the drug are minimal. 
Moreover, the drug is given orally, rather 
than administered through intravenous 
infusion. 

"Traditional chemotherapy is usually 
cytoto.xic — it kills cells. And when it kills 
cancer cells, it kills some of your healthy 
cells,"" said Linda Van Le. associate profes- 
sor of obstetrics and gynecology. "And side 
effects associated with traditional 
chemotherapy can include hair loss and 
decrease in white blood cell count. When 
white cell count is decreased, a major 
concern is an increa.sed risk of infection."" 

According to Van Le. LY353381 does 
not have these side effects. However, there 
may be hot flashes and an increased risk of 
deep venous thrombosis, fomiation of blood 
clots in veins. 

For more information, see htip::! 
\v\v\v.unc.cdiilnewslnewsseiyliinivlserm2IO 
OlW.lwn. 

New biomarker could 
improve screening for 
cervical cancer 

Researchers at UNC are studying 
the value of a new biomarker for improving 
cenical cancer screening. 

The clinical trial will examine cenical 
smears for lelonierase. a protein released 
into cells when chromosomes shorten, stick 
together and become genetically unstable. 
TTie protein helps rebuild eroded telomeres, 
the caps at the ends of chromosomes. Its 
presence in cervical cells removed during 
Pap smear testing may help predict which 
women are at greatest risk for developing 
cancer. 

"Pap sme;ir screening has been very ef- 
fective at decreasing the number of deaths 
from cervical c;incer. but many of the abnor- 
mal results it produces do not lead to an 
increased risk of cancer."" said John 
Boggess. MD. assistant professor of obstet- 
rics and gynecology. ""A lot of women 



undergo expensive testing and painful 
procedures only to find out they've got 
something that doesn't need treatment or is 
unlikel\ to become cancer."" 

According to Boggess. a gynecologic 
oncologist. Pap smear sensitivity is only 70 
percent and can be as low as 50 percent in 
women w ith ulceration and innammation of 
the cer\ ix. conditions commonly found in 
women with cancer. More than 2.5 niillion 
abnormal Pap smears are reported in the 
United States each year. 

For more information, see httpill 
www. line. echi/new.s/new.s.'ieiT/univ/cen'i 
callllOI'-N.htm. 

New molecular clues may 
help control herpes 

A UNC study may have identified a 
new way to halt herpes simplex \ irus in its 
molecular tracks. 

The findings — though still too basic 
lor clinical use — shed new light on how 
this stubbornly, persistent virus reproduces 
itself within nerve cells and may suggest 
possible ideas for designing therapies aimed 
at specific molecular targets. 

"The picture that"s emerging is that the 
virus, because it"s an intracellular parasite, 
subverts nomial regulatory cellular mecha- 
nisms in ways that optimize its own replica- 
tion."" said Steven L. Bachenheimer. PhD. 
professor of micrt)biology and immunology. 

Reporting in October"s .loiirnal of 
\irolog\. Bachenheimer and Tim L 
McLean, a student of genetics and microbi- 
ology, noted that a cellular protein kinase 
called JNK. (pronounced "junk"") seems 
important for herpes simplex virus type- 1 
(HSV I) to replicate. HSVl is the highly 
transmissible herpes virus associated with 
painful cold sores. 

"If we inhibit the activity of JNK. we 
see a reduction in viral yield in the cell,"" 
Bachenheimer said. In some cells, the 
reduction was significant, he said. Viral 
replication w as down about 70 percent. 

F(ir more information, see http:ll 
www.Hnv.edulnewslnewssenUmivDicpeslOl 
399.htm. 



16 



Protein in Epstein-Barr 
virus causes B cell 
lymphoma in mice 

UNC scientists, wcirking u ith Loiieagues 
in Japan, have proven that a protein called 
latent membrane protein I in Epstein-Barr 
\ inis causes a fomi of c;incer known ;i.s B cell 
hinphomainmice. 

The work is important, the scientists 
say. because it shows the protein's central 
role in Epstein-Barr \ irus" ability to change 
normal cells into cancerous ones. TTiat \ irus 
already is known to cause infectious 
mononucleosis in humans and has been 
associated w ith such malignancies as Bur- 
kett's lymphoma. Hodgkin's lymphoma and 
ncse and throat cancer. It is especially haz- 
ardous to AIDS patients and other patients 
w hose immune systems ha\ e w e;ikened. 

""We have show n for the first time that 
Epstein-Barr virus clearly can cause 
cancer."" said Nancy Raab-Traub. PhD. pro- 
fessor of microbiology. ""Now we can go 
after the specific protein that is responsible 
and perhaps one day stop that protein func- 
tion and pre\ ent the cancer from grov\ ing." 

The first report on the continuing 
research appeared in the Proceedings of the 
National Academy of Sciences last year, and 
a second describing additional findings in an 
October 1W9 issue of the journal Science. 

For mure information, see http:ll 
wM'w.itnc.edulnewslnewssenlreseanhlraah 
ilODVW.htm. 

Gene mutation tied to 
deafness in blacks, whites 

A new UNC study is the first to 
establish that a gene mutation associated 
w ilh about 20 percent of all cases of hercdi- 
lar\ deafness found in white people is also 
tiiutul in blacks. 

"There have been some reports m the 
scieniillc literature on Caucasians, but onK 
a small stud\ on African-Americans, anil 
they didn't find the mutation." said Eliza- 
beth .VI. Rohlfs. PhD. clinical assistant 
prolessor of pathology and laboratory 
medicine. 



Rohlfs and colleagues tested DNA 
samples of 50() w hites and 5(X) blacks for the 
mutation knov\n as 35-delete-G (35delG). 
Healthy carriers of the mutation carry only 
one cop\ from either their mother or father. 
When each parent has a copy, one in four 
offspring risks inheriting a pair and is bom 
deaf. These are the odds for inheriting a 
recessive genetic trait. 

""We found a two percent carrier 
frequency of .\'^-delete-G in Caucasi;uis and 
a 0.4 percent carrier frequency in African- 
.Americans."" Rohlfs said. 

In North Carolina's general population, 
this ratio translates to a frequency of one in 
10.000 for whites and 1 in 2.^0.000 for 
blacks. The findings were reported at the 
annual meeting of the American Societ\ of 
Human Genetics in San Francisco. 

For more inforniation. see Imp:// 
iiiru./(/i( .('(//( news neusserv/univ/diieneK) 
iwyjimi. 

Gamma tocopherol 
may boost risK of knee 
osteoarthritis 

A component of vitamin E. known 
as gamma tocopherol, may somehow 
contribute to arthritis, a unique new study of 
\ ilamin E and the painful degenerative 
illness suggests. 

The study, described at a recent 
American College of Rheumatology news 
conference in Boston, also suggests that bas- 
ing a high proportion of alpha tocopherol - 
the most common ingredient in \ itamin E - 
relative to gamma tocopherol ma\ help 
prevent arthritis, at least in knees 

Joanne Jordan, MD, research associate 
professor of medicine, presented the finil- 
ings. A member of the Thurston Arthritis 
Research Center. Jordan is principal iinesti- 
gatorof the Johnston Counts Osteoarthritis 
Project, a large, gosernment-sponsorcd 
studs of the illness that lor Ihc lirsi nmc 
incluiles m;uis black subjects. 

/•(</■ more informcilion . sec Imp." 
www. line Clin iie\vs:i)ew\serv research jodu 
nlll7W_lirm. 



17 



Alumni Profile 



This Doctor is No Stranger to Writing 



By Melissa Matson 

Frank Huyler. MD. MPH "93. enjoys 
observing the world around him. 
That characteristic has served him 
well in his career as an emergency room 
physician. It has also served him well in his 
avocation; writing poetry and prose. 

Following up on a suggestion to write 
about his ER experiences. Huyler recently 
hit the road on a book tour promoting The 
Blood ofSlnmi;crs: Sloric.s from hjii('ri;cncy 
Medicine. In his book, he sought to recount 
interactions with patients in ways that 
would challenge his readers. 

"There's a lot of hype surrounding 
emergency medicine." said Huyler. "And I 
saw this book as an opportunity to offer an 
honest look at an often misrepresented 
world." 

In one story, for instance. Huyler 
describes caring for the victim of a gunshot 
wound. .After rirshing his patient to surgeiy 
and spending the night w ith him in the ICLI. 
Huyler learned that the man \*.as a murderer 
He w rites: 

When I came lo sec him. before sunrise. I 
found a police officer silting in a chair 
reading a magazine. The policeman 
yawned when he saw me. put down his 
magazine, and came out lo talk. "He's a 
had one," he said, gesturing to the mon- 
strously distorted figure. "We think he 
killed at least two convenience store clerks 
last year." "Really .'" The cop nodded. 
"Killed them both, after he'd got the 
money... Right through the head. We've 
been after him for a \ ear." 

The child of two itttemational school- 
teachers. Huyler grew up overseas, in the 
United Kingdom. Japan. Brazil and Iran. 
"Growing up overseas, being a foreigner, 
encouraged me to sit back and look at the 
bigger picture." said Hu> ler. "It helped me 
as a writer." 

In his late teens. Huyler decided to go 
to Williams College, a liberal ails college in 
Massachu.setts. where he earned a Bachelor 
of Arts in English. It was during that period 
in his life that he began to v\ rite seriously. 
"Williams College was very fertile ground 
for me in that respect." said Huyler. "I had 
access to some ver\ prominent writers v\ ho 
ga\e me \aluable ad\ice and encourage- 
ment. I've continued to w rite ever since." 




Frank Huyler. MD. MPH. V.^ 

Despite his obvious affinity for writing, 
he decided to pursue a career in medicine. "I 
wanted a sense that the daily v\ork I did v\as 
important and that it had a tangible and real 
impact on people's lives." he explained. "I 
never considered the possibility of being 
able to support myself through writing. " 

With that motivation, he applied to and 
was accepted by LINC's School of Medicine. 
"I was really fortunate in going to UNC." 
said Huyler. "I was under the false impres- 
sion before school started that I'd have to 
put my interest in the humanities on hold. 
But v\hat I found is that L'NC emphasizes 
the humanities in addition to the practical 



side of medicine." 

Among his mentors at UNC were Judith 
Tintinalli. MD. MS. chair of Emergency 
Medicine, and Jim Manning. MD. associate 
professor of emergency medicine, who 
.served as his career goal advisor. "TTiey went 
out of their way to be supportive." said 
Huyler. "And they encouraged me to 
consider emergency medicine for my career." 

After graduation. Huyler w ent to Albu- 
querque. New Mexico, for his residency. 
While there, he started on his first book. 
"My department chair. Dr. Da\id Sklar. 
liked to write, and he knew that I did also." 
Huyler said. "So he suggested that I write 



18 



about ni\ experiences in the ER t'lir ni\ residene_\' 
prujecl. 

"I think it's all too easy in medicine to torget that 
what you're seeing is remarkable. So the 
remarkable becomes mundane. " Hu\ ler said. "Every 
once in a while, it's good to sit back and take stock ot the 
work we do." 

Editor's Note: As of our publication date. The Blood of 
Srnini;ers. published by Unixersity of California Press, 
can be purchased on the Internet at Amazon.com 
( S 1 .^47 ) or BamesandNoble.com ( S 1 .^.% ). 



Frank Husler's book. The Blood of Stnmaers. has 
recei\ ed numerous review s by literary critics. Among 
them are the Boston Globe. The New Yorker, and 
Publishers Weekly. Huyler also writes poetry. Some 
of his poems have been published in The Athiiuu 
Monthly. Poetn. The Georgia Review and the 
Carolina Quarterly. At the current time, he is 
finishing a book of poems and working on a no\e 

"Huyler's w riting is sharp and spare, clean as a 
scapel. . . Tliis volume is a modest jewel, a 
compact, faceted gem that shines with intelli- 
gence. And. like the work of those more senior 
doctor/w riter/philosopher kings who precede 
him. it proves that even in these days of lawsuits 
and HMOs, there are doctors and nurses who 
iruK \aluethe lives in their charge." 
Boston (ilohc. 9/2^/99 

"This haunting, exquisitely observed 
collection of medical \'ignettes is much 
more than a compilation of odd cases 
from the emergency room. Huyler probe 
beneath the surface to reveal the marrow 
<il his encounters with patients." 
I'Khlishcrs Weekly, mo/99 

"His uork shows the econonis ami sharp 
altention that both jobs |H.R. physician ami poet 
demand. " 
The AVii Yorker. 9/6/99 




19 



Women in Leadership 



Bv Melissa Matson 



Willie the fictional Dr. Quinn may 
have been an unusual fixture 
in her 180()s setting, women 
doctors are commonplace at the turn of the 
millennium. 

According to the Association of .Amer- 
ican Medical Colleges, nearly 50 percent of 
medical school applicants are women. As a 
result, the number of female physicians is 
rising dramatically. And that fact has led to 
an increased desire among women to take 
on leadership roles in the medical field. 

In academic medicine, leadership 
opportunities have been relatively slow in 
coming. The AAMC found that in 1998, 
only 27.4 percent of medical school faculty 
members were women. It also found that 



"the proportion of women faculty at the 
rank of full professor has remained virtually 
constant during the past 17 years." Another 
interesting fact: the average number of 
women department chairs per medical 
school is one. 

Though there are more women in med- 
icine, there are not a proportional number of 
women in leadership positions. One possi- 
ble reason is women's efforts to balance 
career and family. Currently, most tenure 
tracks — the traditional way to advance in 
academic medicine — do not allow women 
to take time off to raise children. 

Another possible reason is that women 
tend to have fewer networking and mentor- 
ing opportunities than men. "Like members 
of minority groups, women faculty mem- 
bers have a much harder time obtaining the 
necessarv mentorine and buildinii net- 



works." said Janet Bickel. associate VP in 
the AAMC's Division of Institutional Plan- 
ning and Development and head of the 
Association's Women in Medicine program. 
"Men tend to underestimate the extra chal- 
lenges that result v\ hen you don't see people 
w ho look like you in positions of power." 

UNC's School of Medicine is a little 
unusual in that female doctors have a vari- 
ety of leadership roles, including several 
department chairs, deans, division chiefs 
and committee heads. Tlw Medical Alumni 
Bulletin sat dow n w ith four of them to find 
out what their experiences in academic 
medicine have been like. 

Judith Tintinalli, MD, MS 

For Judith Tintinalli. MD. MS, chair of 
the Department of Emergenc> Medicine, 
eender has made little difference in her 




Juclnh Tiniiikilli. MD. MS 



career, "rm fortunate to be in a specialt> 
that's relatively new. And because of that, 
it's open to anyone w ho is sman. \v illin!: to 
work hard and good at w hat the\ do." said 
Tiniinaili. 

She found the same to be true during 
her earl\ ciyeer in internal medicine. "I had 
no problems because I was a woman during 
medical school or residency." Tintinalli 
said. "All the way through. I assumed peo- 
ple would treat me for w ho I u as."' 

■".And now that Tm in a position of 
leadership. I make it clear that I ha\ e no 
gender agenda." said Tintinalli. "I do think 
women ha\e to consider issues that men 
ma\ not. but 1 want to see cvcryniu- who is 
good get a chance. 1 don't like to sec polar- 
ization."' 

Her advice to people, male or female, 
w ho w ani to enter academic medicine — 
develop good clinical skills, learn how to be 
a gtKxi administrator, and de\ elop a niche in 
scholarh acti\ilies. "In academic medicine, 
the path to promotion includes all three."' 
said Tintinalli. 

Valerie Parisi, MD, MPH 

Valerie Parisi. MD. MPH. chair of the 
Department of Obstetrics and Gynecology, 
thinks that despite the positive changes for 
women in medicine, gender is still an issue. 
■"For the most part, people in academia 
consider themsehes gender neutral." said 
Parisi. "But m\ experience in OB/Gyn. 
which is a surgical specialty, has been that 
gender neutrality is not necessaril\ the 
nomi." 

Parisi points to the fact that few female 
doctors are in positions of "real"' leadership. 
"Most women seem to stop in middle man- 
agement." said Parisi. "Out of 125 medical 
schools, only seven or eight have female 
OB/Gyn chairs." The result, says Parisi. is 
thai young women have few female role 
models. 

Like Williams. Parisi is a strong ad\o- 
cate of mentoring. "".Mentoring is crucial no 
matter who you are." Parisi said. ""And I tell 
my students that the\ shouldn't have just 
one. ThcN need twii or three w ho can help 
w ith different aspects of their career." 

Among Parisi "s hopes for future female 
phNsicians: greater undersiandmg through- 
out academic medicine of the value ot female 
leaders and their potential contribution to the 
system. ""We don't want to lose gifieil 
women to second class jobs." Parisi saiil. 

Carol Lucas, Phi) 

In the case ot C aroi l.ucas. PhD. chair 
of the Department of Biomedical IJigineer- 
ing. she is a bit of an oddil\. "\]\ field is 
strongly lied to mathematics and engineer- 
ing."' said Lucas. "'For that reason. I was 




often the (MiI\ woman in ni\ classes or 
workplace." 

But. said Lucas, that too Is changing. 
According to her. biomedical engineering is 
a specialty that has proven attract i\e to 
women. "You might call it the softer side 
ot engineering." Lucas said. "This field has 
tangible links to human beings that makes li 
more appealing to women than tiadiiumal 
engineering." 

For Lucas, being a woman in acaiiemic 
medicine has been both positive and 
nei2ati\e. "'1 call it m\ lite as a token 



\alcncl\insi.\ll).\ll'll 

woman." saul Lucas. "Vox insiance. \ears 
ago. 1 was named president ol .ui interna- 
tional organization. That"s because the 
members couldn"t decide which of the men 
to appoint. Since 1 wastlieonlv worn. in. 1 
made the decision an easier one. " 

What Lucas tlid find challenging in her 
earl) career was securing grants and 
publishing scholarl\ articles. '"1 didn"t have 
the same network of contacts that main of 
my male counterparts iliil." Lucas said. 
■"Because ot that. 1 wasn'i able lo liiul out 
about as main oppoilunilies." 



Now. as one of the oldest women in 
her field. Lucas tries to mentor those just 
beginning, "rm in a position to help other 
women get started." said Lucas. "And now. 
there's beginning to be a network that 
enables women to talk with and learn from 
others who have gone before them." 

Roberta Williams, MD 

Roberta Williams. MD. chair of the Depart- 
ment of Pediatrics, notes that her specialty 
w as one of the first to welcome w omen. 
"The result is that the younger generation of 
pediatricians is predominantly female," said 
Williams. "Pediatrics is a very open disci- 
pline in which women are encouraged to 
move up the ranks. So it"s also a natural fit 
for women who have an interest in leader- 
ship." 

The only barrier Williams sees for 
women in academic medicine is the same 
lor women of any profession. "The question 
is "How will they manage their reproducti\e 
\ears?"" said Williams. "1 think that we 
need to look at how we can give women an 
opportunity to participate in academia and 
still have a family. We need to consider 
things like job sharing and part-time tenure 
tracks." By doing so. believes Williams, 
academic medicine can ensure that it v\ ill at- 
tract and keep talented people. 

She recommends that women interest- 
ed in academic medicine do tv\o things. 
First, tlnd a mentor. "Women don't take ad- 
vantage of mentoring to the degree that men 
do." said Williams. "Women need to gi\e 
some thought to w ho has the best tools to 
help them direct their careers." 

Second, assert your needs in the areas 
of time, salary and position. "Traditionally, 
women sell themselves short." Williams 
said. "All too often, women agree on a 
salary only to find that a male colleague 
makes more. Then they are dissatisfied." 




Canil Lucas. PhD 




RohcitiiWilluinis.MD 



22 



Development 

Notes 



Donations benefit hospital 
chaplainc\ program, plastic 
surger\ research 

It's not often that nionev gi\en to The 
Medical Foundation has an ob\ ious and 
direct clinical impact. But in the case ot 
James and Hannah Bagwell's gift, it does. 

In lys^). the Bagwells, who live ni 
Washington. North Carolina, established 
the William Roberson Bagwell Chaplainc\ 
Fund in niemorN of their son. who died 
that \ear of a brain tumor Bill had ser\ed 
as UNC Hospitals' first chaplain dedicated 
to patients with HIV and AIDS until his 
death. His parents sought to keep their 
son's ministr> alive by helping to finance 
the chaplain program for that special 
patient population. 

Last .\o\ember. the Bagwell's added 
$50. 000 to the fund. In part, that monev 
has gone to support the work of Peter 
Mafflv-Kipp. chaplain to AIDS patients at 
UNC Hospitals since 1991. "This ministrv 
is an essential one in this hospital, and it 
would not have been possible w ithout the 
Bagwell fund." said Mafflv-Kipp. 

On the research side. James Valone. 
.MD. a retired plastic surgeon from 
Raleigh, and his wife. Ethel. recentl\ 
committed SI million to The Medical 
Foundation to establish the James A. and 
Ethel F. Valone Plastic and Reconstructive 
Surgerv Research Fund. The generous gift 
was stnictured so that part will be donated 
outright on an annual basis, and part will 
be received from the Valones' estate. 

"Dr. and Mrs. Valone and their famil\ 
are long-time friends of our program, and 
they know that we have very strong 
clinical and teaching components." saiil 
Gerald Sloan. .MD. chief ot the Division of 
Plastic Surgerv. "But thev saw what we 
need to take our program to the next 
level — to strengthen our research " 

So the Valones established the fund 
to help "kick start" scholarship in the 
division. Specificalh. it will allow the 
Division of Plastic Surgerv to recruit facultv 
to set up significant research projects. 

"A wonderful thing about this gift is 



that It's unrestricted." Sloan said. "That's 
great in teniis of recruitment and great in 
teniis of getting residents involved in the 
research. External grant funding is so 
unpredictable, but the Valone fund will 
help keep our research projects going 
independent of that." 

Centers recei\ e seed grants 
from Excellence P'und 

Five nationally recogni/ed L'NC 
research centers recently received seeil 
grants from The Medical Foundation E.xcel- 
lence Fund, an annual fund for friends of the 
School of Medicine and UNC Hospitals. 
Recipients included Lineberger Comprehen- 
siv e Cancer Center, the C\ stic Fibrosis/ 
Pulmonarv Research and Treatment Center, 
the Birth Defects Center, the Bow les Center 
for Alcohol Studies and the Thurston .Anhri- 
tis Research Center. 

Each center received a S.'^.OOO seed 
grant to fund promising projects — research 
leading to new treatments and cures but not 
far enough along to receive national funding. 
"Seed grants allow researchers to get the data 
they need to apply for national grants." said 
Shelley Earp. MD. director of the Lineberger 



Compreheiisiv e C;uicer Center 

"I know I speak for each center when I 
sa\ we are thrilled with these gifts." said 
Fulton Crew s. PhD. director of the Bow les 
Center for .Alcohol Studies. "Tliey w ill help 
us continue some v eiy innov ative research." 

The Cvstic Fibrosis/Pulmonary 
Research and Treatment Center plans to 
use its griuit to purchase new equipment for 
a researcher who is studying how infection 
begins in the lungs of infants diagnosed 
with CF 

The Birth Defects Center will use the 
money to start a newsletter and to help fund 
education of health care professionals 
regarding folic acid as an effective means 
of birth defect prevention. 

The Bow les Center for Alcohol Stud- 
ies' grant vv ill he used to prepare education/ 
prevention materials on fetal alcohol 
svndrome. the leading cause of biiih defects 
including mental retardation. 

In addition to these seed grants. The 
E-xcellence Fund supports medical student 
research awards, a distinguished teaching 
professorship, the Family Day program for 
families of medical school students, student 
travel grants, student lounge renovations 
ami other special programs. 



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2?! 



Medical Alumni 

WEEKEND 



May 4-7, 2000 



GENERAL INFORMATION 

Accommodations 

Blocks of rooms have been reserved at the following area hotels. 
Alumni are responsible for making their own reservations by 
contacting the hotel directly. 

The Sheraton Chapel Hill (formerly the Omni Europa) 
919.968-4900 ext 4.^ or I -S()()-.^25-35.^.'S. fax 9m-942-.V'^57. 
(Contract: UNC Meilical .Alumni .Accommodations, cut-off date 
4/5/00. Rate: $ll9.00-t-». 

The Carolina Inn 919-933-2001 or I -800-962-S3 19. fax 
919-962-3400. (Contract: Annual Medical School Alumni & 
Reunions, cut-off-date 4/14/00. Rate: SI49.00-H). 
The Siena Hotel (headquarters for the Class of 1960) 
919-929-4000. fax 919-968-6170. (Contract: UNC Medical Alumni 
Reunion, cut-off date 3/5/00, Rate: $155-h). Be sure to mention the 
contract name when making your reservations and plea.se note the 
cut-off dates. Other area hotels: The Hampton Inn (919-968-3000). 
The Holiday Inn (9 19-929-2 171). The Best Western University Inn 
( 9 1 9-932-2000 ). The Comfort Inn University ( 9 1 9-490-4949 ). 

TENTATIVE WEEKEND SCHEDULE 

Thursday, May 4 

1 1 a.m. Class Reunion Golf - the New Finley Golf 

course. Shotgun start. Infomiation regarding 
sign-up mailed directly to members ot 
reunion classes. Pre-registration is required. 

Friday, May 5 

9:30 a.m. -3 p.m. Registration Desk Open. Carolina Club/ 
George Watts Hill Alumni Center. 
L'NC campus. 

10 a.m. -Noon ,\nnual Business Meeting. Dowd Room. 

Carolina Club. (All Alumni Welcome) 
Election of officers and councillors. Lunch 
provided for attendees following the meeting 
by pre-registration onl\. 

Noon- 1 p.m. National Loyalty Fund Steering Committee. 

Peebles Room. Carolina Club ( Lunch included ). 

1:.W- 2:30 p.m. The Fighteenth .Annual Spicer-Brecken- 

ridge Memorial Lecture. 103 Ben-yhill Hall. 
Shuttle bus ser\ice will be pro\ idcd from the 
Alumni Center. 



3-5 p.m. 



Speaker: M. Therese Southgate. MD. .Art 
Editor J on null af the Aincncan Mcdual 
Association. 

Fndowment Board Meeting (Selection of 
2()()0-20()l grant recipients) Dmvd Room. 
Carolina Club. 



Reception and Annual Alumni Banquet 

( Ptv-n'siistnition leqitiied) 

Alumni Hall I. II. III. Carolina Club. George 

Watts Hill Alumni Center. UNC Campus. 

6:30 p.m. Champagne & Wine Reception 

7:15 p.m. Dinner Seating. *Recognition of alumni 

fundraising campaigns 'Presentation of 
Distinguished Service Awards and Distin- 
guished Faculty Award "Recognition of 
recently retired faculty. 



Saturday. May 6 

8 a.m.- 12:30 p.m. 



CMF: Clinical Application of Anticoagula- 
tion Therapy 

* 



CLASS REUNIONS 

Class of 1945 Saturday. May 6. Carolina Inn. Social & 

Dinner 
Class of 1 950 Thursdas. May 4. Cocktails & Dinner 

Class of 1 955 Saturday. May 6. Hope Valley Country Club. 

Durham. Social & Dinner 
Class of 1960 Saturday. May 6. The Siena Hotel. Tuscany 

Room. Social & Dinner 
Class of 1 965 Saturday. May 6. Cocktails & Dinner 

Classof 1970 Saturday. May 6. Carolina Club. Cocktails 

& Dinner 

Class of 1 975 Saturday. May 6 

Class of 1980 Saturday. May 6 

Classof 1985 Saturday. May6. Anderson Park. Carrboro. 

Picnic 
Class of 1 990 Saturday. May 6. The Carolina Inn. Reception 

■All schedules below are tentative. Final Plans included in class 
mailiiiiis. 



24 



President's 
Letter 



Greetings Fellow Alumni. 

B\ the time \ou receive this issue of the 
Bulletin, those of us fortunate enough - or 
ill-fated enough, depending on your point 
of view - to have experienced the snow - 
slomi of the centun, will have returned to 
our usual activities and daily routine. 

The severe weather caused the cancel- 
lation of the Wake County Deans Recep- 
tion, hut others are scheduled in Guilford. 
Forsyth. Mecklenburg and Cumberland (a 
first! ) counties as well as in .Atlanta. These 
are outstanding opportunities to sociali/e 
with fellow alumni and others w ho are 
significant supporters of the medical 
school. It also offers a chance to get the 
current scoop on the state of the school 
and renew a sense of connectedness to 
each other and Chapel Hill. John Foust 
will likely remind you that your ri\al 
county in the Loyaltv Fund Campaign is 
set to triumph over you in the current 
drive. I hope to have the pleasure of seeing 
you at a reception in your area. 

The highlight of the \ear for the Gener- 
al Alumni Association is the Spring 
Alumni Weekend. Reunion committees 
are busy planning a festive time for their 
classes ( see page 24 ). 

Outstanding alumni and facultv will be 
recogni/eti at the banquet, which also will 
serve as the moment of truth for the Lo\ - 
alty Funti Campaign. This is a wonderful 
time to be in Chapel Hill and I hope man\ 
of you can come. One of the opportunities 
my office affords is to participate in meet- 
ings of the Board of the General Alumni 
Association. This is a dedicated group of 
Tar Heels who oversee a sers effective 
organization that provides excellent 
service to alumni. 

Among other enjoyable activities at the 
winter meetings w as the opportunitv to re- 
view the master plan for the L'NC campus 



for the next decades (as rev iewed else- 
w here in the Bullciin). The concept is 
wonderful. The execution may not be 
complete in my lifetime, but the 
existence of this commitment is a great 
comfort to those of us w ho treasure the 
Chapel Hill of ourfomiative years. 

Well, enough of this sentimental 
rambling (a prerogative of advancing 
vears). Hope to see vou in Chapel Hill in 
Mav. 

Gordon B. LeGrand. MD -65 




CME/Alumni Calendar 

March 24-26. 2000 — Chapel Hill 

Clinical Relevance of Medicinal Herbs and Nutritional 

Supplements in the Management ot Major Medical Problems 

March 26-April 1, 2000 — Chapel Hill 

Physicians Medical Management Program. Kenan-Ragler 
Business School 

April 5-7, 2000 — Chapel Hill 

24th Annual Internal Medicine Conference 

April II, 2000 — Chapel Hill 

Emergency Medicine Research Forum 

April 29-30, 2000 — Chapel Hill 

I5th Annual Meeting of the Glomerular Disease Collaborative 

Network 

May 4-7, 2000 — Chapel Hill 

UNC Medical Alumni Weekend 

For moie infonnalion about CME courses, contact the Office of 
Continuing Medical Education. (919) 962-21 18. or toll-free 
through the Consultation Center. (800) 862-6264. To contact 
the Alumni Affairs office, call (919) 962-6786 or e-mail 
medical_alumni@nied.unc.edu. 



Estate Planning Notice 

Many individuals would like to make a major gift to the 
UNC medical center, but cannot commit current assets / 
for such a purpose. Through a will, however, anyone 
can make a more significant gift than they might ever 
have thought possible by designating a specific sum, a 
percentage, or the residue of their estate for the benefit 
of the medical center. 

To provide a bequest, simply include a paragraph in 
your will naming The Medical Foundation of North 
Carolina, Inc. as a beneficiary. For example: 

"/ give, devise and bequeath (the sum of$ ) or 

( % of my estate) or (the residue of my estate) 

to The Medical Foundation of North Carolina, Inc.. 
a 501(C)(3) created to maintain fimds for the UNC 
medical center with principal offices located at 880 
Airport Road, Chapel Hill, North Carolina!' 

This language creates an unrestricted bequest for use by 
the medical center when and where the need is greatest, 
or you may specify that your gift be used for a particular 
purpose. 

For further information on bequests, contact Jane 
McNeer at (919) 966-1201, (800) 962-2543, or 
jmcneer@email.unc.edu. 



PERIODICALS DEPARTMENT 
HEALTH SCIENCES LIBRARY 

CAROLINA CAMPUS 7585 



Nonprofit Organizatiim 

U.S. Postage 

PAID 

Chapel Hill. NC 
Permit No. 24 




Medical Alumni 



BULLEnN 



Sdiool of Medicine, University of North Carolina at Chapel Hill 







i 



Dean's 
Page 



The missit)!! ul Ihe UNC School ol 
Medicine reminds us thai w c 
were created to improve the 
health ol the people of North 
Carolina. 

For the past 27 years, one of the ua\s our 
niissit)n has been most tangibly 
realized has been through our involvement 
with and leadership of the Area Health Edu- 
cation Centers (AHEC) Program. 

AHEC was created by a group of vision- 
ary leaders to address the stubborn prob- 
lems of both the shortage and 
maldistribution of primary care physicians 
and other healthcare providers in our state. 
From the outset, we realized this ct)uld not 
be a venture of our .School alone, but wouki 
require close ccdiaboration with all 
five UNC-CH health affairs schools, as 
well as Ihe other acatlemic health centers in 
the state. 

Working with our colleagues and using 
AHEC as the bridge, we have been able to 
provide community-based training experi- 
ences for our students and residents, while 
offering our expertise to practicing profes- 
sionals in even the most rural and under- 
served communities. 

Today, the AHEC program remains the 
linchpin of a broad anay of educational ini- 
tiatives designed to prepare physicians and 
other healthcare pro\ iders to meet the needs 
of the stale. 

For our School, it would be impossible to 
have a class size of 1 60 without the eapacils 
the AHECs and the AHEC faculty afford us. 
More than 40 percent of the clinical training 
of each medical student occurs in an AHEC 
setting, and AHEC rotations continue to re- 
ceive evaluations by students that are at or 
near the top of all clinical experiences. 
Reading through student evaluations gives a 
sense of the importance these experiences 
play in the life of UNC medical students. 

Recent examples include comments such 
as "I learned so much about primary care 
medicine. It was a great experience." or ""the 
attendings really enjoy teaching and al- 
lowed me the right balance between autono- 
m\ aiul supervision. ..this was the best 



experience t)f m_\ medical career thus far." 

AHEC also pro\ ides a means by which 
the School can fulfill its ser\ ice mission. 
Last year, more than 440 specialty clinics 
were pro\ ided by our faculty in towns and 
cities across that state that would not other- 
wise have priority access to such sub-spe- 
cialty care. In addition, our faculty taught 
some .^.'iO Continuing Medical Education 
programs and provided technical assistance 
to countless health-care pro\ iders 

AHEC also offers the iiili astriiciure 
through which we can resptind rapidl\ to 
urgent healthcare needs when they arise. At 
the time of the flooding in eastern North 
Carolina last fall. AHEC proved a vital re- 
source for faculty who offered clinical ser- 
\ ices to communities in the affected areas. 
Through regional AHECs. we also were 
able to pro\ ide training programs for 
health-care pro\ Iders and other human 
service workers dealing w ith the emotional 
aftemiath of the tragedy. 

AHECs capacity to adapt to the chang- 
ing needs of the state has been critical to its 
success through the years. Currently the 
School of Medicine and the other health 
atfairs schools are working closely with 
AHEC on a new strategic plan for 2001- 
2004. As we build on our core programs for 
students, residents and practicing 
health professionals. I anticipate this plan- 
ning process will help shape our opportuni- 
ties to respoiul more effectively to 
important concerns. 

We will address such issues as increasing 
the number of undeirepresented minorities 
in medicine and other health careers; using 
infomiation technology to improve our edu- 
cational programs and increase access to 
health care; strengthening our primary care 
and prevention programs; and improving 
our efforts to give patients and the general 
pLiblic better information about their health 
and ways to enhance it. 

The North Carolina AHEC program has 
become a standard of excellence for similar 
efforts throughout the nation. It provides our 
Schixil of Medicine with a statewide class- 
room for students, residents and healthcare 




practitioners of all types. 

As AHEC engages in a planiung process 
that sets its course tor the next four years. I 
am confident it will demonstrate once again 
how careful attention to the needs of the 
state, high-quality education programs and 
cooperation w ith other institutions can be 
combined to achieve a farsighted and pur- 
poseful fulfillment of the School of Medi- 
cine's mission. 



Ofl}d^ L- &tufC 



Jcffivx L. Hiuipl. Stn 
Dean. Sclu><:l„t Mi, Heme 



Medical Alumni 
Association Officers 

President 

Gordon B. LeGiand. MD "65 
Rcileii;li 

President-Elect 

PaulE. Viser.MD"84 
Clinlon 

Vice President 

Thomas J. K(H»nt/. MD "66 
Wliistfiii-Stilciii 

Secretar> 

Ralph L. "Wall Jr.. MD "78 
Wiiisidii-Siilc'iii 

Treasurer 

William M. Hcrndon. Jr.. MD "81 
Charlotlc 



Editorial Staff 

John W. Stokes 

Vice President. Fiihlic Ajfairs & 

Marketing 

Dcbra Pierce 
Mdiuiiiini; Eclilar 

Michele Blevins. Katherine Kopp. 
Leslie H. Lang. Melissa Malson. 
Karen Stinneford. Lynn Wootcn 
Contrihiitiiiii Wrilers 

Dan Cra\\l(ird ipus. 14. l.-^i 

Ja\ NUmgunKpgs. 6. 10. 1 1.20.2!) 

I'hoUniniphcrs 

The Meilu at Ahimiii Hulliim is piihlisheil lour liiiicv 
annually by ihc L'NC-Chaix-I Hill Medical .■\lunini 
A.ss<x;ialion. Chapel Hill. NC 275 14. Poslajic is p.ml 
by ihe non-pnifit associatinn through I'.S. Postal 
Permit No. 24. Address correspondence to the editi u. 
Office ol Medical Center Public Affairs. .School , il 
Medicine. CBWTNIO. University of North ( ■.irolm.i. 
Chapel Hill. NC 275 14 



Medical Alumni 

BULLETIN 

School of Medicine, Iniversitv ot North CaroUna at Chapel Hill 



Contents 


Features 


.A Natural t'orL'NC Neuroscience 6 


Miiiniu Protilc: Daniel Biim n, MD, 't>5 S 


UNC Surgeons Pertorni .Slate's [-iisi "Doniino" LiverTransplanl 10 


L'NC Health C;u"c Aequires Rex Healthcare 12 


Match Da> 2()()() and Pearls otWisLloin 14 


.AHEC: Taking Medicine lo Ni>nh Carolina's Coinniunilies 16 


Kids allNC Hospitals rseC'ompulers To ralkWilhOlher Sick C'hildien IS 


l-Miih\ Profile: Fuller Award Winner Harve> Hanirick. MD 20 


Departments 


Dean's Pace Inside Front Cover 


Research Briefs 2 


NewsBriels 4 


lacullv Notes 22 




Development Notes 24 


I'lesuient's Letter Inside Back Cover 


C.\lF./.\lunini Calendar Back Cover 


Oinlh ( n\,i Ihc Dull nil,. II led An innn\.ili\c li\ci li. mspl, ml oilers mnic Ik >|X- h'l iliIkhIs 


in,ol,,l>s .l„\ \Uur.;i,m 



Research 
Briefs 



UNC, Duke, starting search 
for osteoarthritis genes 

It's not dilTicLilt to I'lnd a I'amily in whicli 
generation after generation has struggled 
w ith the same inherited disease. The ehal- 
lenge is finding the genetie hnk to understand 
how iihiesses. sueh as osteoarthritis, are 
passed down Iroiii parents to their otTspring. 

An international researeh network com- 
posed ot'se\en unisersity medical institutions 
including UNC"s Thurston Arthritis Re- 
search Center and Duke University Medical 
Center have just begun the largest study ever 
to look tor that link, the genetic susceptibility 
toosteoailhritis. 

The most common form of arthritis, os- 
teoailhritis is a chronic conditiim that allects 
more than 21 million Americans. B\ anaK/- 
ing DN.A and health histories from man\ pa- 
tients, researchers believe they vv ill better 
understand the role that one or more genes 
play in the condition's development. The 
goal is to find new and more etfective medi- 
cines. The academic research institutions are 
v\i>rking together with the Center for Human 
Genetics at Duke and Glaxo Wellcome, a 
pharmaceutical company. 

/■'('/■ //;<■ ///// \!(>n, sec littp://\v\v\\.iinc.cdii 
/ncws/iicwsscry/icscuivh/jiinliinl IM>'-)'->.l}lin. 

Study finds no evidence that 
hormone benefits autism 

Parents will go to great lengths to help 
children w ith illnesses, including trying the 
latest well-publicized treatments regardless 
of w hether they "v e been prov en effectiv e. But 
if a theiapv sounds loo good to be true, it usu- 
ally is. 

A new' study, which appeared in the New 
EugUmdJdiirnal of Medicine, offers a prime 
example of this. Contrarv' to w hat early pub- 
licitv suggested. North Carolina researchers 
found no ev idence that a single dose of the 
synthetic human hormone secretin benefited 
children w ith autism. 

In a well-controlled study of 60 children, 
half of whom received synthetic secretin and 
half of whom received an inactive salt solu- 
tion, scientists could tell no difference be- 
tween the groups when the studv ended. The 



investigation was double-blind, meaning that 
neither clinicians nor parents knew w hicli of 
the two treatments the children received until 
ev aluations were complete. 

lor more infomiation. see hnp./Annv.uiic. 
edi(/ne\vs/newsscn/reseairMiodfisl\l2SW.Imn. 

UNC scientist finds smallest 
number of genes needed for 
organism's survival 

The minimum number of protein-producing 
genes a single-celled org;misni needs to sunive 
and reproduce in the laboratory is somewhere 
between 265 and 350, according to new re- 
search directed by a top UNC scientist. 

L'sing a technique know n as global trans- 
poson mutagenesis. Clyde A. Hutchison III. 
PhD. professor of microbiology, and col- 
leagues at The Institute for Genomic Re- 
search in Rockv ille. Md.. found that roughlv 
a third of the genes in the disease-causing 
Mycoplasma genitalium were unnecessary 
tor the bacterium's surv iv al. 

The technique — a process of elimination 
— involved randomly inserting bits of 
unrelated DNA into the middle of genes to 
disrupt their function and see if the organism 
thrived aiiyvv ay. 

.Stich research is a significant step forward 
111 creating minimal, tailor-made lite forms 
that can be further altered for such purposes 
as making biologically activ e agents for treat- 
ing illness. Hutchison said. More immediate- 
Iv. it boosts scientists" basic understanding of 
the question. "What is life .'" 

For nunc infonuation. see hup: //www: unc. 
cdii/iHws/iiewssen/researcMmuh 12999.htm. 



UNC selected as mutant 
mouse resource center 

The National Institutes of Health selected 
UNC as one of tw o Regional Mutant Mouse 
Resource Centers in the nation. The new cen- 
ter will receive a grant of S660.000 annually 
ov er fiv e years. 

UNC and the University of California at 
Dav is w ill facilitate more w idespread use of 
mouse models in basic and translational re- 
search throutihout the countrv. Such models 



have revolutionized scientists' ability to 
probe mammalian biology and disease and 
hav e become a v akiable resource. 

The new centers will expand the already 
strained capabilities of Jackson Laboratories 
in Bar Harbor. Maine, to characterize, 
maintain and distribute an ever-growing 
anav of mutant mouse models to the research 
community. 

"One of the problems is that people can 
generate lots of models, but these won't be 
accessible w ithout a repository w here they 
can be quality controlled, checked out and 
distributed." said Terrv Van Dv ke. PhD. pro- 
fessor of biochemistry and biophv sics. 

For more information, see liup://\\ww:une. 
edii/ne\\s/ne\\ssen/resecinli/m(Hisel2l7W.liim. 

Cooperation marks new era i 
of cancer research 

In the new millennium, cooperation ■.— 
rather than keen-eyed competition — may 
signal a new era of federally funded research 
lor the nation's top scientists who develop 
and study mouse models of cancer. 

In a bold strategy, a UNC scientist will 
share the helm of the Mouse Models of 
Human Cancer Consortium, a cooperative of 
14 university-based research teams from 
around the nation, each indiv idually funded 
bv the National Cancer Institute ( NCI ). 

"It's reallv ven exciting — it's a paradigm 
shift in the w ay most people do science." said 
Teny Van Dvke. PhD. professor of biochem- 
istrv and biophysics. "Most who do science 
do so independently, and are worried about 
the competition and who gets the credit. Now 
each team will have some money to work on 
their own animal models, and pursue their 
own indiv idual ideas, but will also participate 
in a larger scale cooperative group. 

"There will be extensive sharing of ideas, 
results and reagents." she added. 

Molecular fats prevent nerve 
sheath abnormality 

.A studv led bv scientists at UNC points 
to a group of fats crucial to the proper fomia- 
tion of the myelin sheath surrounding 
nerv e fibers. I 



Although the new trndings ha\e no direct 
clinical implications tor human disease. the\ 
help sohe a scientific puzzle while adding 
new know ledge to the molecular biolog\ of 
iinelin and diseases of m\elin loss, parlicu- 
larh multiple sclerosis. 

M\elm. which is 3()-pcrcent protcm and 
7()-percent lipid — or fat — tonus the multi- 
membrane shield that surrounds ner\e 
axons, hair-like extensions of nene cells that 
snake off and make connections w iih other 
nerve cells. These m\elinaied connections 
fonn the u iring circuitr\ of both the central 
nervous systems, which includes the brain 
and spinal cord, and the peripheral nervous 
sxsiem. 

Foi till' full article, sec lntp://\\w\\.um .ccIk 
/ih"n \/iic\\ sscir/ivseanli/iiiycliii 1 2 1 Jyy.litiii. 

.\voiding vitamins A, E might 
improN e cancer tlierapv 

X'uamins .A and H. w hich normallv boost 
human health in numerous ways, also appear 
to keep cancer cells from dying through the 
natural protective process scientists call 
apoptosis. new UNC research show s. 

.As a result, giving patients those vitamins 
niav prevent cancer cells from self-destruct- 
ing and work against cancer therapv. scien- 
tists say. 

nie UNC researchers presented their find- 
ings at the .•\merican .Society for Cell Biolo- 
gv's annual meeting in Washington. D.C. 
Rudolph .Salganik. PhD. research professor 
of nutrition, and Terrv Van Dvke. PhD. pro- 
fessor of biochemistrv and biophvsics. di- 
rected the studies. 

"We believe this work is important be- 
cause it ma\ make cancer treatments more 
effective." Salganik said, "it suggests that 
cancer patients, especiallv those undergoing 
chemotherapy or radiation therapv. mav do 
better on an antioxidant-depleted diet." 

hiiniiiirc liitdniuitidii \cc liltp://\\'\\M:iiiic.cdii 
/twws/iwwsscn/rcHiin li/viiiiinik l2lJW.Iitiii. 

Newer oral contraceptive 
may be less liarmful for 
women smolders 

Oral conlraceptivcs arc known to increase 
the risk of heart problems for smokers, aiul 
new research at UNC suggests that might be 
due in part to the specific Ivpe of hormones 
contained in "the pill." 

Older "second-generation" oral contra- 
ceptives have a higher androgenic coiilenl 



because of the tvpe of progesterone hormone 
used w hen compared to new er "third-genera- 
tion" fonnulations. 

For all women, older oral contraceptives 
prtiduced higher blood pressures and more 
resistance to blood flow inside blood vessels 
during stressful situations, the UNC suidv 
showed. 

.A report on the findings a|ipcaicd in the 
Januan issue of Ohsictrics and Gyiiecoloi;}. 
■Authors include psv chology graduate stu- 
dent Patricia Straneva and Susan (iirdler. 
PhD. assistant professor of psychiatrv 

For mine information, sec hllp://w\vu:tini . 
eihi/ne\v.\/ne\\sseiv/ivseaiili/i;inllcii)l()^K).litm. 

Cystic fibrosis experiments 
offer hope for improv ed 
treatments 

.Although not vet ready to trv their new 
technique in patients. U.NC scientists have 
successfulK repaired a genetic problem that 
accounts for a form of cystic fibrosis com- 
monly seen in patients of European Jewish 
descent. 

Kenneth Friedman. PhD. research lellow 
in pathologv and laboratory medicine, and 
Rvszard Kole. PhD. professor of phaniiacol- 
ogv. dev eloped the method to correct a miita- 
tion involv ing unnecessarv information 
inside a gene. When that gene is imperfect, 
cystic fibrosis results. 

The two conducted the research in collab- 
oration with UNC's Lawrence Silverman. 
MD. and Michael Know les. MD. and Duke 
Universitv 's Jonathan Cohn. MD. and tech- 
nician Jolanta Kole. 

"This work builds on a strategy first ex- 
plored by Dr. Kole in his studies of beta-tha- 
lassemia. a genetic disease often seen in 
Mediterranean and some Asian couniiics 
and involv ing defective hemoglobin mole- 
cules that lead to red blood cell destruclion in 
bone marrow." Friedman said. "We applied 
his method to a cvstic fibrosis gene mulalioii 
discovered here at L:NCin iw"i." 

/■(// the lull \liir\. sec hltp://\\\\\\Aiiic.cdii 
/ni'w \/iic\\\si n/rc\C(inli/li'lcmiiJI2U)W,liiiii. 

Experts to study informed 
consent in national gene 
transfer research 

Investigating ethical issues surrounding 
recent ami upcoming genetic discoveries w ill 

be Ihe L'oal (da new S')7.S.()(I(I National 



Human Genome Research Institute award to 
L'NC tacultv members. 

Gail Henderson. PhD. and Nancv King. 
JD. both professors of social medicine, 
will lead the three-vear elTort. sponsored b> 
the institute's Ethical. Legal and Social Im- 
plications of the Human Genome Project 
program. 

"\\ hen Dr. James Watson set up the 
Human Genome Project, he required that a 
certain percentage of its budget be set aside 
to fund studies of the genome project's ethi- 
cal, legal and social implications since it 
raised so manv questions." Henderson 
said. "Our work relates to how people under- 
stand genetic research in tcinis of the 
consent process, 

"We're planning to invesiigalc how bene- 
fits are described and understood in gene 
transfer studies, which just about everybody 
calls gene therapy." she said. "People think of 
these studies as therapy but they are not at all. 
The> are reallv just earlv research that we 
hope will eventualh lead to better treat- 
ments." 

For the full slorw sec lutp://\\\\\y.unc.cdu 
/nms/nc\\sscir/resciucli/licndciill llXXI.htm. 

UNC study may help clarify 
how cells grow 

.A studv led bv a UNC scientist sheds new 
light on the process of cell growth regulation. 

The studv. which focuses on ihe complex 
network of biochemical signals between pro- 
teins and en/v mes w ithin cells, helps clarify 
how those signals initiate or limit cell 
growth. 

.Although still too basic for clinical use. 
the findings suggest the possibility of new 
tlrugs that wiiuld target specific growth-in- 
tlucing molecules within cancer cells. A re- 
port of the studv appeared in the science 
journal Wuun . 

Lee Graves. PhD. assistant protessor of 
pharmacologv and the suidv s principal m- 
\ esiigalor. saiil the cii/v me M.AP kinase 
(M.APKi IS a kcv component of a signaling 
palhwav iniliatetl bv growth factors. 

"This IS just one of manv signaling |ialh- 
wavs. but we know it's essential for growth." 
he said. "So the kcv question has been, w hat 
are the specific targets of MAP kinase'.' That 
is. what are the impoilant things it does, and 
how doe^ It regulate cell growth'.'" 

lor more uiloriuation. see http://\\\\\\.uni . 
edii/neus/ne\\ssen/rcseanli/,cll<)l2lKXI.hinL 



News 
Briefs 



Medical school to create 
genetics center 

The School of Medicine will receive $2.6 
million over four years from the Howard 
Hughes Medical Institute to help de\ elop and 
staff a new genetics center. 

"The genetics center will complement ex- 
isting research strengths at Carolina in the 
studs of mouse models of diseases, genetics 
of model organisms, cancer research and 
chnical genetics." said Williatn F. Mar/luff. 
PhD. executive a.ssociate dean for research. 

"The money will establish the genomics 
core technologies we need on campus, in- 
cluding a chromosome imaging facility for 
detecting alterations in cancer, as well as ab- 
normalities in genetic diseases." he said. 
"It will also be used for recruiting four 
young faculty members working in mam- 
malian genetics." 

Ot \()5 U.S. medical schools competing 
for the Howard Hughes grants. L'NC w as 
among 41 w inncrs. Awiirds ranged from $1 .6 
million toS4 million. 



NIH awards UNC, Duke $21 
million to boost care for AIDS 
patients, research 

AIDS specialists at UNC and Duke will 
iecei\'e S2I million from the National Insti- 
tute of Allergv and Infectious Diseases over 
the next fixe years to continue their battle 
against the deadly illness. 

The money is part of renewed national 
Adult AIDS Clinical Tnals Group ( A ACTG 1 
funding. It w ill suppoil care for people li\ ing 
w ith .AIDS across North Carolina and clini- 
cal trials that already have resulted in far 
more effective treatments than were first 
axailable and promise further medical 
progress, the physicians say. 

"Since the beginning of the AIDS epidem- 
ic, the AACTG has made enormous contri- 
butions in helping people with HIV li\e 
dramatically longer and healthier li\'es." said 
Anthonv S. Fauci. MD. director of the insti- 
tute. ".A.ACTG studies ha\e been and will 



continue to be an invaluable source of scien- 
tific data, significantly advancing our ability 
to treat HIV." 

UNC's effort, led by Charles van dcr 
Horst. MD. professor of medicine, and 
Joseph Eron. MD. associate professor of 
medicine, will get $12.5 million. Duke's 
effort, directed by John Bartlett. MD. associ- 
ate professor of medicine, will receive 
$8. .5 million. 

New program leaders named 
at cancer center 

Marci Campbell. PhD. and Andrew Ol- 
shan. PhD. have been appointed as program 
leaders at the Lineberger Comprehensi\e 
Cancer Center. 

Campbell, assistant professor of nutrition. 
will lead the Cancer Prevention and Control 
Program. 

This program works v\ ith communities, 
health care pro\ iders. schools and other 
agencies to promote adoption of healthy be- 
haviors — including diet, smoking cessation, 
physical activity and cancer screening — 
with an emphasis on acti\ ities in rural, un- 
derser\ed and minority populatiiins. 

Scientists also are investigating a wide va- 
riety of other topics, including issues faced 
by cancer survivors and new approaches to 
cancer prevention. 

Olshan. associate professor of epidemiol- 
ogy and research associate professor of 
surgery, will lead the Cancer Epidemiology 
Program. 

Researchers in the program are in\estigat- 
ing disease patterns in the population to iso- 
late possible causes of cancer, such as 
lifestyle and the en\ ironment. as well as to 
identify groups at high risk for cancer. 
In combining epidemiology with basic sci- 
ence using molecular and genetic en\ iron- 
mental/ lifcstv le exposures. 



UNC performs videoscopic 
surgery 

For millions of Americans, heartburn isn't 



just an occasional aggravation. Rather, it is 
an cNcrvdav misery that forces them to con- 
tinually consume over-the-counter antacids 
and prescription medications and keeps them 
aw ake at night. 

Now those painful days and sleepless 
nights can be eradicated, thanks to a video- 
scopic surgical procedure being performed 
by physicians at UNC. 

"Estimates show that l<S million people 
in the United States suffer from chronic 
heartburn or what is known as gastroe- 
sophageal reflux disease, or GERD." said 
Mark J. Koruda. MD. professor of surgery 
and nutrition. 

"While antacids and medications may re- 
lieve symptoms for occasional heartburn, 
they don't offer comfort for some one million 
chronic sufferers. For these folks, videoscop- 
ic surgery can be a long-term solution to an 
everydav problem. " 

In the \ ideoscopic surgical procedure now 
being offered at UNC Hospitals, the physi- 
cian makes fi\ e to six small incisions — each 
less than one inch — to make room for spe- 
cial surgical instruments, including the la- 
pai\)scope. 

While the videoscopic procedure is new. 
the surgery itself is not — it has been around 
since the 1930s. But traditional surgery re- 
quired surgeons to make a long incision in 
the abdomen, a painful operation from w hich 
patients took a long time to recov er. 

Lineberger awarded 
$25.3 million renewal 
grant from NCI 

The Lineberger Comprehensive Cancer 
Center has received a five-year. $25.3 million 
grant from the National Cancer Institute to 
renew support for its cancer research pro- 
grams. 

The amount represents a 94 percent in- 
crease from the center's previous five-year 
grant, one of the largest increases ever award- 
ed b\ the institute's cancer centers program. 
All of the funds will be used at UNC. making 
this grant one of the largest ever awarded for 
research at the universit>. 



"The Lineberger Center has done a re- 
markable job of bringing taeuh\ together 
from ail the health affairs schools, and in- 
creasingl\. other parts of the campus, to bear 
upon the problem of cancer." said Jeftre\ 
Houpt. MD. dean of the school of medicine. 

"Its intcrdiscipiinars research efforts are 
ground-breaking."' 

Said H. .Shellon Earji. MD. center director. 
"In the past live years, the I'NC Lincbcrger 
Center has grown dramaticall}. fashioning 
inultidisciplin;u-\ clinical care programs \\ ilh 
LNC Hospitals and UNC Heahh Care as 
well as conducting outstanding clinical, pub- 
lic health and basic cancer research. National 
recognition of our superb scientists and 
ph\ sicians has increased commensurately. 
With this renewal grant. NCI has recognized 
the qualit\ and cimtinued promise of our re- 
search and clinical efforts." 



UNC Hospice excels during 
recent Joint Commission 
accreditation 

LNC Hospice, part of the L^NC Health 
Care System, receixed the highest designa- 
tion possible during a recent re\ iew by the 
Joint Commission on Accreditation of 
I Icalthcarc Organizations. 

Preliminar\ findings from the accrcilita- 
tion re\iew showed that LNC Hos|iicc 
scored yy out of I (K) points. 

This marked the first time L'NC Hospice 
hud undergone re\ iew by the Joint Commis- 
sion, an independent, not-for-profit organiza- 
tion that is the world's leading health-care 
standards setting and accrediting bod\. 

LjNC Hospice, formerlx' Hospice ol 
Chatham County, has scrvcil tcrininalK ill 
patients and their families for \h \cais. flic 
l.^-emplosec organization became pari ol 
CNC Health Care in .April \W-) and scr\cs 
Chatham and Orange counties. 

Judy Li pa. executive director of INC 
Hospice, said the Joint Commission accredi- 
tation lends even more credibility to an orga- 
nization that already prides itself on 
deliverin;: evcelleni care. 



".Although more and more hospices are 
seeking Joint Commission accreditation, 
only about 5 percent complete their initial 
surveys at the same high level L'NC did. so 
we obv iouslv are excited about that." she 
said. 

To earn and maintain accreditation, an or- 
ganization must undergo an on-site survev by 
a Joint Commission survev learn al least 
everv three vcars. 

Federal funds awarded for 
training clinical researchers 

The School of Medicine has won federal 
funds to train some of its best and brightest 
young doctors for careers in clinical research. 

The Clinical Research Cumculum .-\w.ird 
comes from the National Institutes of Health. 
The award helps prov ide an in-depth two- 
year training program for eight to 10 junior 
faculty, each of whom is committed to a ca- 
reer as a clinical investigator, according to 
Eugene P. Orringer. MD. executive associate 
dean fiir facuhy affairs. 

"Over the last decade, there has been a 
dearth of young physicians who pursue clini- 
cal research as their career goal. It's not a 
local problem, but rather a national problem." 
he said. "The NIH created this award to pio- 
V ide institutions such as UNC w ith the sii|i- 
port for the infrastructure necessarv to tram 
these young people." 

L'NC was one of .^.'i medical iiisiiiLilions to 
win the award, which pro\ ides S2()().()(K) per 
vear over five years and is renewable. For 
purposes of this award, clinical research in- 
cludes patient-oriented research, epidemio- 
logic and behavioral studies, ami 
(nitcomes-oricnled heahh scrv ices research. 
.\l Carolina, trainees will lake courses in 
those areas through the schools of medicine, 
public health and pharmacv. A new Iv de- 
signed seminar program locuseil on ilrug ile- 
velopment will supplement those courses. 
.All trainees will also design antl carrv out a 
comprehensive clinical research pio|ccl 

Al the heart of the program is a novel men 
loring system in which senior lacullv mem 
hers work closelv with Irainees. helpiii'j llieiii 



w ith coursework and research, and w ith set- 
ting and then achiev ing their long-term ca- 
reer goals. 

"We have created a program that has both 
breadth and depth." Orringer said. "We are 
paiiicularlv pleased with the close exposure 
each trainee will gel to faciiltv members and 
other trainees." 

He added that most of the trainees will 
have written a NIH grant pi\)|iosal hv the end 
ol their second y ear in the program. 

But. Orringer added, while NIH funding 
supports the program's infrastructure - in- 
cluding a portion of the salai v for senior fac- 
ulty inxohed - it does luu pro\ ide the 
stipends needed to pay the trainees. This 
meant reaching out to attract additional funds 
from other sources. 

"We knew that wiilnn the next decade or 
SI) a lot of clinical research would involve 
drug devektpment. including clinical trials."' 
said Orringer. "So w ith that locus. I felt we 
could go to industry and ask tor help lo su|v 
port some of the trainees."' 

.And so far the plan has mel w iili success, 
l-'inancial support for trainees eniollcd in ihe 
new program has been obtained from the 
phannaceutical giant Eli Lilly and Company, 
from Pharmaceutical Product Development 
Incoiporated (PPD-Pharniaco). a clinical re- 
search organization, and from the American 
Academv t)f Phannaceutical Phvsiciaiis. 



A Natural for 
UNC Neuroscience 




/);: Sniilcr ilistiisscs a computer imuf^c with Dr. Ahiiui Jiukiiuiii. 



By Leslie H. Lang 

Williuiii "Bill" Snider has an 
ambitious goal; He wants to 
make UNC a major national 
plaser in 21st-century neuro- 
science reseaivh. 

To that end, this tall, atfabie. soft-spoken 
native of western Kentucky must don several 
hats — that of college recruiter, \isionary. 
fund raiser, program director, and. of course, 
scientist. 

For the new head of UNC's Neuroscience 
Research Center, that last cluipeau is a natur- 
al fit. A pioneer in neuronal growth factor re- 
search. Snider and his work on proteins that 
reijulate the survival and erovvth of neurons 



are lamiliar to most senior scientists in the 
field, indeed, his research reputation had qui- 
etlv si)lidified during a 16-year tenure at 
Washington University in St. Louis. 

And when it came to selecting a top scien- 
tist who could also toot the Tar Heel mega- 
phone for neuroscience recruiting and 
fund-raising. Snider's UNC legacy helped 
make him a natural choice. Both his mother 
and her sister earned degrees in Chapel 
Hill, and Snider earned both his bachelor's of 
science in niatheniatics and medical degrees 
here. 

"1 grew up in this little town in Keiituckv 
called Hopkinsv ille. and for reasons I don't 
fulK understand, my grandfather sent two of 
his daughters dow n to Chapel Hill." he said. 



"And this was back in the 19.^()s when there 
were few w omen here. So my mother and her 
sister were ainong the first women to do their 
last two years of college at UNC." 

While her son was excelling in science 
duiing high school. Snider's mom made him 
aware of the National Science Foundation 
prizes for talented science students. 
These were intensive summer programs in 
science education. Her suggestion that he try 
for one held at UNC might have been an indi- 
cation that she smiled at the memory of her 
Carolina days. 

"So that's how 1 first got here the summer 
after my junior year in high school, and 1 
just loved it." Snider said. "Later I applied to 
and got accepted by UNC and Duke. So I 



picked UNC." 

The furnier math major eredits a ph\ Mcal 
eheniistrx professor tor introducing him 
lo the biological world of nerve axons 
and synapses. 

"Lee Pederson gave me a book by Sir 
Bernard Kat? called Ner\e Muscle Synapse."' 
he said. "It's a famous book about the 
process of synaptic transmission at 
the neuromuscular junction, the synapse 
between ner\es and muscle. And 1 found it 
fascinating. It seemed to have a \ery logical 
and quantitati\e aspect that w as also appeal- 
ing to me.'" 

During his first year in medical schoiil. 
Snider was exposed to neurobiology through 
a course taught by Edward Perl. Mf^. cur- 
rentU Sarah Graham Kenan Professor of 
Cellular and .Molecular Phy siology at UNC. 
In 1971. Perl was recniited to UNC from the 
University of Utah to strengthen neuro- 
science at Chapel Hill. It was Perl who 
helped recruit his former student to take over 
the helm of UNC's Neuroscience Research 
Center 

"The combination of exposure in neurobi- 
ology in that course, and my tascinalion w ith 
neurosciences through pre\ious con\ersa- 
tions with Dr. Pederson. just did it for me that 
1 was going to be in\()l\ed in this field." 
Snider said. ""I think a lot of us with interest 
in biological science struggled with the issue 
of w hether to pursue graduate training or 
medical school training. For many, this has 
been solved by the combined .MD-PhD pro- 
gram. But this option didn"t exist \^hen I was 
at L'NC. 1 might add that Dr. Perl also strug- 
gled with this issue." 

So lascinated b\ neurosciences was 
Snider that he took a y ear off after his tlrsi 
year in medical school to pursue a tellowship 
arrangement Perl helped organize w ith s|-)inal 
cord phy siologist Motoy Kuno. Kuno. who 
had been recruited by Perl w hen he became 
department chaimian. was particularly inter- 
ested in the interactions between the motor 
neurons in the spinal cord that inner\ale 
muscle cells. Sniderexplained. 

"He formulated ideas about trophic' in- 
teractions, trophic' having to do with nour- 
ishment, in that the muscle nourished the 
innervating neuron." he said. ",\t the linie we 



had no idea about the molecules in\ol\ed in 
this. So I guess I became fascinated w ith 
those questions, and my subsequent career 
has largely been de\t)tcd to study ing the mol- 
ecules that mediate these trophic interactions 
in the nerxous sy stem." 

■After graduation in 1 977. Snider elected to 
continue clinical training and interned at the 
Har\ard-affiliated Beth Israel Hospital in 
Boston. He then completed a residency in 
neurology at Cornell, at the time considered 
the premier neurology training program in 
the nation. While at Cornell, he met his wile. 
Barbara, w ho was completing her psychiatric 
training at Paine- Whitney. She is board-certi- 
fied in child ps\ chiatry. 

As it turned out. Snider eventually was 
able to combine both science and clinical 
work. He accepted a post-doctoral fellow- 
ship at Washington University and subse- 
quently joined the neurology faculty. 

"My clinical interest was neuromuscular 
disease, including amyotrophic lateral scle- 
rosis (commonly referred to as Lou Gehrig"s 
disease or ALS), peripheral neuropathies and 
pain."" he said. ""I was able to tie together w hat 
1 worked on in the laboratory and observed in 
clinic patients." 

But Snider allowed that after Id years in 
St. Louis, he had "reached the stage in my ca- 
reer when the opportunity to develop and 
lead something sounded very appealing."" 

Word that his old alma mater was setting 
up a neuroscience center, a research center 
that wt)uld cross various disciplines at the 
medical school, and that there would be a 
substantial tlnancial commitment for faculty 
space in a new building seemed to Snider the 
perfect challenge. A return to Chapel Hill 
also seemed a sweet symmetry. 

Snider"s goals for the center arc ambitious. 
In his temporary office at the UNC Lineberg- 
er Comprehensive Cancer Center, he be- 
comes more animated when he eagerlv 
outlines them. One can readily sense his pas- 
sion for the work. 

"1 would like to combine a couple of 
themes in basic and clinical neuroscience 
that will be very inlluential in the 21st centu- 
ry."' he said. "The first of these is develop- 
mental neurobiology, aiul mv tlrsi mission 
v\ ill he lo slienglhen and evpaiul the tlevelop- 



ment of that area on campus here. 

"t)ur ability to understand how the brain 
tonus, how particular types of nerve eel Is dif- 
ferentiate and send axons to the appropriate 
regii)ns of the brain and not to other regions, 
how synapses fomi and lunction - molecular 
genetics has opened up this field in w ay s that 
could not hav e been imagined a decade ago. 

".And so I plan to make brain development 
the first area of effort for the Neuroscience 
Reseiu"ch Center."" he said. "This will primar- 
ily involve people working on mouse mod- 
els, using the genetics ot the mouse to 
understand the genetic basis for how the 
brain dev elops. 

".A second goal, perhaps one that w ill 
make the center unique, is to combine issues 
in developmental neurobiology and research 
related to clinical neurology,"" he added. ""We 
would focus panicularly on issues related to 
repair of the nervous system, repair of dam- 
age after spinal cord injuries and after stroke. 
It is almost certain that the same things that 
govern neural development will be important 
for nervous system repair."'Snider noted that 
the center itself will not go into treatment at 
the level of clinical trials. 

"Wc arc interested in the science lounda- 
tions of therapy related to brain and spinal re- 
pair, and so we would be try ing ti) recruit 
people who would be studying the surv ival 
of nerve cells, differentiation of nerve cells. 
gR)w th of axons of nerve cells, and we would 
also be interested in recruiting people who 
are attempting to repair the nervous sy stem 
after injuries,"" he said. "This is working 
beautilully in mouse models now."" 

But Snider is not averse to peering into ihe 
future forclinical applications. 

"The great progress in isolating human 
embryonic stem cells means that we might 
potentially apply the know letlgc of develop- 
mental processes to the successful repair 
of nervous system injuries m |ieople,"' 
he saul. 



Alinniii Profile 



Dr. Daniel E. Brown: Pc: 



By KathtTiiu' Kopp 

When Daniel E. Brow n giadii- 
aled from the UNC School ol 
Medicine in 1965. he didnl 
begin lo know how far — lit- 
eralK — he w ould go in his career. 

Though most of his work as a pediatri- 
cian has taken place in Raleigh. Brow n last 
vear spent Iwo-and-a-half months half a 
world away serving on a medical mission 
team in .Africa. 

He said it is no exaggeration to sa\ the 
experience changed his life. 

This year. Brown celebrates his 3.5th re- 
union year. His career path is familiar to 
many physicians; After graduating, he com- 
pleted an internship and residenc\ in pedi- 
atrics at Shands Hospital, now part of the 
University of Florida-Gainesville hospital 
svstem. including a year as chief resident. 
Then he entered the U.S. An Force. 

■'Back then, we had what was called the 
Berrv Program." he recalled. "If you en- 
tered this program, you had a commitment 
to mililai7 service for a period of time." 

So after completing his medical training. 
Brown and his wife. Barb;ua. a graduate of 
the UNC School of Nursing, spent two 
\ ears at March Air Force Base near River- 
side. Calif 

In 1470. Brown, a natne of Selma in 
Johnston Coiintv. retiimed to North Caixili- 
na and |oined the Raleigh pediatric practice 
of Frank Winslow and Frank Poole, two 
well-respected North Carolina pediatri- 
cians. The practice is now known as Blue 
Ridge Pediatrics: Brown is one of five pedi- 
atricians in partnership there. 

Brown credits his mentors with helping 
hmi refine his skills as a pediatrician in his 
earl\ \ears of practice. He also learned a lot 
from the e\ents of his own life. When he 
and Barbara mo\ed lo Raleigh in 1970. the\ 
w ere the proud parents of three young 
daughters. Deborah. Jennifer and Virginia. 
Like most pediatricians. Brown acknowl- 
edged that becoming a parent himself 
tautihl him more about carini: for children - 




Daniel Brown. '65 and one of his patients are all smiles on his reeent trip to Kenya. 



and their parents — than textbooks and lec- 
tures ever could. 

"Once you ha\e your ow n children. \ou 
really begin to understand sour patients and 
their families." he said. 

In 1976. the Browns welcomed a fourth 
child into their faniih. Daniel E. Brow n Jr. 
The follow ing v ear. young Dannv died from 
a metabolic illness. 

"That event changed our li\es." Bmw n 
said simply. "It changed our lives, and it 
taught me a lot." 

In manv wavs. the famih 's tragic loss 



represented a turning point for Brow n. both 
personalK and professionally. 

".After our son died. I felt I had so much 
more empath\ for families who were going 
ihrough difficulties." he said. "Whenever I 
had contact w ith a famih w ith a seriously ill 
child or a family w ho lost a child. I could re- 
allv empathize with what they were going 
through. And in a lot of ways, losing our son 
tested my faith, but it also made it stronger." 

Brown, a devout Christian and a member 
of Pro\ idence Baptist Church in Raleigh, is 
unafraid to profess his beliefs. .And through 



liatrician with a Mission 



the years he has put his faith into action, most 
recently doing medical mission work. In 
1994. he joined a medical mission team 
sponsored hy Baptist World Relief. 

"Our team tra\eled to Zaire for three 
w eeks to care for children orphaned by the 
ci\ il w ar in Ru anda." he said. "Though I \\ as 
only there for a feu weeks, the experience 
had a major impact on me. It piqued in\ in- 
terest in mission \\ ork." 

In 199.>. Brown attended a conference in 
Asheville calleti "Prescription for Renewal." 
sponsored h\ .Samaritan's Purse, a relief iir- 
ganization headed by Franklin Graham. 

"Samaritan's Purse has an arm called 
World Medical Mission." explained Brow n. 
"They send \olunteers all over the world to 
pro\ ide medical care and assistance." 

After attending the conference. Brow n 
was detemiined to take another mission trip. 
After some research, he set his sights on 
going to Tenwek Hospital near the tow n of 
Bomet in a remote part of western Kenya. 
The logistics of taking extended lime off 
from private practice were challenging. 

"It took almost three \ears to get e\er\ - 
thing in place so I could be gone for two-and- 
a-half months." Brown said. "It takes a lot of 
effort and cooperation from your partners to 
work out something like this. It's hard to be 
out of the office tor such a long period of 
tunc." 

Brow n's w ife and their s oungcst daughter. 
a teacher, accompanied him to Keny a. 

.As might be expected, practicing pedi- 
alncsin Kcn\a is light \ears awa_\ from prac- 
ticing in Raleigh. 

"In pediatrics today, you still see a lot of 
acute illness, but pediatrics has detlnitel> 
changed over the years." Brown said. "Now 
in private practice, we spend a lot more time 
working through situations like attention 
deficit disorder and psychological and hc- 
ha\ ioral problems. These kinds of issues take 
up much more time than in the past. 

"The was pediatrics is practiced has 
changed as well." Brown continued. "We 
used to just pick up the phone and call w hen a 
child needed to sec a specialist like a neurol- 



ogist or a surgeon or a gastroenterologisl. 
Now we have to look at the list from the pa- 
tient's insurance company, which may or 
may not have the name of the physician 
\ ou'd like to refer to on it. and go from there. 
There's a lot more bureaucracy and paper- 
work than there used to be." 

In cimtrasi. Brow n discovered that practic- 
ing pediatrics at Tenwek meant treating one 
acLite. often life-threatening, illness after an- 
other. .And as far as making refeiTals to spe- 
cialists' 

"There's not much access to specialtv care 
in western Kenva." said Brown. "Nairobi is 
more than an hour aw ay by plane and four- 
and-a-half hours by car. and transport to the 
citv is often not available. At Tenwek. there 
are about six staff physicians for 300 beds. 
The rest of the doctors there are part of a 
changing group of volunteers." 

Many of the children Brow n treated in 
Kenya were seriously ill. 

"The biggest problems there were menin- 
gitis, pneumonia and TB." he said. "These 
were often associated w iih AIDS, w hich is 
very common in both mothers and children 
in Africa. We also were dealing with tremen- 
dous problems w ith malnutrition and dehy- 
dration. It's so different from the U.S. Here. 
if vou're sick, it's just a short ride to the hos- 
pital or the doctor's office. There, we serv ed 
a .^OO-square mile area. Patients got to the 
hospital on foot, by mule and occasionallv. 
bv a motored vehicle. There are no ambu- 
lances. Most of the conditions we saw were 
treatable, but for a lot of patients, it's a two- 
dav trip to get to the hospital. These kills 
were really sick by the time they got to us; 
thev were often in critical condition. Some ol 
them came in too sick to save. The first two 
w eeks I u as there, we had 1 2 children die. 

■We had 45-60 kids in the hospital at a 
time." Brown added. "There was a severe 
epidemic of malaria while we were there. ,At 
times, we had two or three kids to a beil. The 
ones we were able to save generallv did well, 
without complications. '"I'ou do see a lot of 
children ilie. and that's hard. But there aren't 
resiiLMces there to care for kids \\ ho surv ive 



but need continuing medical treatment. That 
care is just not readilv available. .As one nns- 
sion nurse said to me. 'There are worse 
things than dying in Africa.'" 

Despite the hard work and many chal- 
lenges. Brown refused to get discouraged 
during his siav in Kenv a. Instead, he focused 
on the progress Tenwek Hospital made to- 
w aid improv ing medical care for the region. 

"The hospital just graduated its first class 
of nursing students." he said. "One hundred 
percent of the class of 2.^ to M) passed the 
Kenv an nursing boards." 

Brow n took great pride in mentiiring a 
young African physician in the hospital's 
new internship and residency program. 

"There are just two medical schools in all 
of Kenya." explained Brown. "In Kenya, stu- 
dents take their boards right after graduation, 
then usually do a one-year internship before 
going to work. There aren't many residencv 
programs in the country, and there are more 
graduates than there are spaces. Tenwek just 
began this new internship and residencv pro- 
gram, and I was verv luckv thai mv time 
there overlapped almost directly w ith .Agnes 
Langat. a young intern doing her pediatric 
training. She was spending a vear rotating 
through medicine, pediatrics. OB-Ci'*i'N 
and surgery, and il was verv exciting to be 
able to work w ith her. During mv time there. 
I was also able to help the hos|iiial tlevelop 
a curriculum for pediatrics. It was verv 
rewarding " 

.All in all. Brov\n's iime at rcnwck Hospi- 
tal was an experience he lio|ies to repeal in 
another vear or two 

"I am sii much moie .ippiecialivc now ol 
all that we have in icrms nf icsoinvcs in this 
countiv." he said. "Our mcilic.il cue. ihe 
availabililv ol Iraiispoilalion. coiiimunica- 
tion sv stems n's so ililfeiciil in .Africa. 
But It was verv ins|iiriiig to me to see |Vo|ile 
of various faiths anil denominations. Iidiii 
all kinils of meilical backgrounds, coming 
together to help enrich ihis part ol the 
world. I'hcie is sd iiuicli oppnriiiiniv iheie u> 
help others." 



UNC Surgeons Perform State '^l 




■Domino " liver donor Jim Hiiiilvr I U'fl). unj rccipicnl Gtirx Bo^ciri;c' cli\ciiysvs ihcir ni.sc with reporters. 



By Karen Stinneford 

UNC surgeons performed a rare 
"'domino"" liver transplant opera- 
lion in March when they put a ca- 
daN'cric liver in one recipient and 
then transplanted that recipient's tlawed-hut- 
lunctionul li\ er into someone else. 

The no\el transplant technicjue — never 
before done in North Carolina — has oc- 
curred only about 30 times worldw ide since 
first performed in Miami in 1996. UNC sur- 
geons said the ■'domino"" approach likely will 
become routine as doctors continue to seek 
new ways to address the critical shortage ot 
a\ ailable cadaveric organs. 

"This represents the ultimate in recycling 
— gi\ ing a person who desperately needs a 
liver one that otherwise would have been 
thrown away."" said Jeffrey Fair. MD. chief of 

10 



the abdominal transplant program at LINC. 

"As long as there are more patients who 
need organs than there are organs available, 
medicine will have to find new ways to help 
people with no other options."" he said. "Ap- 
proaches like a 'domino transplant' w ill ha\e 
to become more commonplace."' 

P. James "Jim"' Hunter. 5S. of Pinehursl. 
was the first person to recei\ e a new liver dur- 
ing the procedure. Hunter suffered from 
amyloidosis, a rare and ultimately fatal dis- 
ease in which his liver produced a variant 
protein — called amyloid — that his body 
could not process. 

Because it wasn"t used or eliminated, the 
protein collected in cells throughout Hunter's 
body, damaging his central nervous system 
and heart. He underwent a heart transplanl at 
UNC in June 1998 and also was placed on a 
w aiting list for a liver transplant, which repre- 



sented the only "cure" for amyloidosis. 

The rationale behind using a liver from a 
patient w ith amyloidosis is that the disease 
progresses quite slowly, said Mark Johnson. 
MD. director of the renal transplant program 
at UNC. Build-up of the abnormal protein 
won't become clinicall_v significant for some 
10 to 15 years, he said, and it will take anoth- 
er 1 5 to 20 years before permanent damage 
results from that build-up. 

"So the functional life span provided by 
one of these transplanted livers easily can be 
2.5 to 35 years." Johnson said. 

So on March I . Hunter receiv ed a normal 
liver from a cadaveric donor. But rather than 
dispose of Hunter's liver — which is the 
noim follow ing such an operation — doctors 
liansplanted it into 49-year-old Gary Bosarge 
ofRichlands. 

Whv w ould Bosarge w ant a defective liver 



^irst 'Domino' Liver Transplant 




Transplant suri;eons Mark Jiilinsiiii. MD. llcfn ami Jcffercx Fair Mi), hclicvc ilmior iransphuiis will help paiunis in need. 



know n to produce a poicntiall\ litc-threatcn- 
ing protein .' His doctors said it is because 
Bosarge's own health problems posed a more 
immediate threat to his lil'e. 

Bosarge sutlers from hepatitis C. a chronic 
mlection that lrequenil> results in pennaneni 
scarring — or cirrhosis — of the li\er. 
Bosarge was infected with the hepatitis C 
\ irus in 1979 when he recei\ed a blood trans- 
lusion after a helicopter crash in South 
America, and his liver had become so scarred 
it no longer worked adequately. As a result. 
Bosarge experienced tremendous pain, 
weakness and bloating and was almost to the 
point of being unable to v\ork. 

"He was in bad shape — sick as a dog." 
said Roshan Shrestha. MD. medical director 
of the liver transplant program at INC. "He 
said that e\er> da\ he could feel himself 
going a little more downhill." 

So I'.NC" physicians offered him Hunter's 
li\er — along with a long laundr\ list of 
problems that might follow if the transplant 
took place. Shrestha said that his patient, who 
has a 1 ."^-year-old daughter, leapt at the op- 



piiilunity. figuring an_\ li\er had to work bet- 
ter than the one he had. 

"He told me. "If I can live 20 iiune \eais. 
I can see my daughter get married." 
Shrestha said. 

Waiting for a completely healthy li\er 
posed problems, too. Johnson said. Gi\'en the 
huge demand for cadaveric organs. Bosarge 
likel) faced spending another year on the 
waiting list before one would become avail- 
able. By then, his health could have deterio- 
rated to where he was no longer a suitable 
candidate for transplant surgery. 

"There are. admitiedlv. a lot of uiiknow ns 
here." Johnson said. "But given what we 
know about amyloidosis and the time it takes 
for the disease to manifest itself, we think Vlr. 
Bosarge could have 20 to .^0 years of good 
health before his new liver starts causing 
problems. And by then, medicine certainly 
will have discovered a more effective treat- 
ment than what we can offer now " 

Fair agreed, adding. "We could have 
thrown the liver away, but it had the poicniial 
to help someone. And whenever \ou can help 



someone, vou should." 

Hunter and Bosarge both left L'NC Hospi- 
tals about eight days after their surgeries. 

Since its^start in 1991. UNC Hospitals- 
liver transplant program has grown into one 
of the largest and most successful in the 
Southeast. Among the program's main 
"firsts" was that doctors here performed the 
slate's first living-related liver traiis|ilani m 
194(1. 

Some 14.724 people in the liniled States 
currentiv aic awaiting a liver transplant, 
accortling to the I'nited Network for 
Organ Sharing. In I9MS. the latest year avail- 
able, about I ..^00 palieiils died before thev 
could gel a new liver. Last year. 4..'i()0 
liver transplants were |XMfoniied in the Unii 
ed States. D 



UNC Health Care Acquires 
Raleigh's Rex Healthcare 



Nearly one year follow, ing UNC 
Health Care's announeed interest 
in aeqiiiring Rex Healtheare in 
Raleigh, the deal was done. Chief 
Kxeeuliv e Offieer Jeffrey L. Houpt. MD. and 
Rex Healtheare Trustees Chairman James B. 
Hyler Jr. announced in mid-.April that Rex 
Healthcare is now part of the UNC Health 
Care System. 

"The new relationship w ill complement 
and expand the existing ser\ ices and pro- 
grams offered hy Rex and UNC, and enhance 
the abilities of holh organizations to ser\e pa- 
tients and families in the greater Triangle 
area," Houpt said. 

Hyler agreed, adding, "residents of Wake 
County will continue to receive the same 
high-quality health care Rex has provided for 
more than 100 years, with the added benefit 
of new programs made possible by L'NC 
capital." 

Hyler said Rex will in\est in additional re- 
sources to better ser\ e the health-care needs 
of a grow ing Wake County and Triangle area 
population. 

"Through our affiliation w ith UNC. Rex 
also w ill gain greater access to high-le\el 
clinical programs, advanced technology and 
medical research," he said. 

Under the agreement. Rex Healthcare w ill 
continue to operate as a separate, private, not- 
for-profit entity and will retain its separate 
identity. Its employees will remain employ- 
ees of Rex Healthcare. 

I'NC and Rex anticipate both growth and 
expansion of ser\ ices and cost-sa\ ings under 
the agreement. 



Governing Boards Reorganize 



The agreement making Rex Healthcare 
part of the UNC Health Care System result- 
ed in changes to both organizations" go\'- 
erning boards and appointments of 
directors for the new ly established John 
Rex Endowment Board. 

The new Rex Healthcare Board includes 
the following current Rex board members: 
William C. Burkhardt, Jean W. Carter, MD. 
James T. Fain III. Charles T. Francis, Ann 
Goodnight, James B. Hyler Jr., Robert A. 
Ingram, Richard S. Myers. MD, and Waltye 
Rasulala, UNC"s appointees to the 
Rex Healthcare Board are: J. Slade 
Crumpton. Eric B. Munson and Thomas E. 
Sibert. MD. 

The UNC Health Care Board includes 
the following current UNC board mem- 
bers; Molly Corbetl Broad. J. Slade 
Crumpton. F-rank .A. Daniels Jr.. M. 



Andrew Greganti. MD. Jeffrey L. Houpt. 
MD, John A. Kirkland, MD, Estell C. Lee. 
William McCoy, R. Malloy McKeithen. 
Eric B. Munson, Valerie Parisi, MD. Bailey 
Patrick Jr., Paul J. Rizzo, William L. Roper. 
MD. Charles M. Shelton and John S 
Ste\ens. Joining the Board from Rex are: 
Jean W. Carter, MD, Richard L. Daugherty 
and James B. Hyler Jr. 

The governing board of the new John 
Rex Endow ment. chartered to ad\ance 
health care in the greater Triangle area, will 
consist of 12 members. Named to serxe at 
the tiine of this printing were: David 
Boerner, MD, Ben L. Bradsher, William C. 
Burkhardt, James T. Fain III. Charles T. 
Francis. ,\nn B. Goodnight, James H. May- 
nard and Waltye Rasulala. UNC"s represen- 
tati\es are Jeffrey L. Houpt, MD. William 
McCoN and William L. Roper. MD. 



The transaction. \ allied at S2yo million, 
calls for establishing a new John Rex Endow- 
ment and funding a number of Joint UNC- 
Rex projects. Financial details of the deal 
include: 

• SI 00 million to go toward the new John 
Rex Endowment. Twenty-f"i\e million of this 
will be returned to Rex Healthcare for capital 
projects. Income from the remaining 
S7.S million will be used to support indigent 
care and enhance communit\ health-care 



programs in the greater Triangle area. 

• S?X million to be committed by UNC to 
fund strategic initiatives jointly agreed upon 
by Rex and UNC. These could include ex- 
panding cancer care, pediatric ser\ices and 
women's serxices. 

• SI 32 iTiillion in existing long-term 
debt to stay w ith Rex Healthcare and its affil- 
iates. These liabilities remain on the Rex bal- 
ance sheet. D 



and Rex Healthcare 



Combined Service Area 



Four County 
Pnmar; Care 



V 




G R A N V I L 



ALAMANCE 



ORANGE 




DURHAM 



WAKE 




I.l 



CHAPEL 
■ HILL 

P'actri-t Pijtuer/ _ Hoscitals 



CHATHAM 

Carolina Dialysis 





VANCE 



FRANKLIN 



Blue Ridge Family Pra 



Rex Primary Care 
of North Raleigh ^ , ^ 

\ Future Sile of '" ' 
Rex Healthcare ' WAKE 
of Wakefield FOREST 
X \ ,^ Wake Forest 

-\" „ , , ,\ V Pediatncs 

Boylan Internal 
Rex HorVie Medicine 

- _ . Health — - 

.lid-Caroliria"" - \_ \ ""• Rex Hospital & 1 

Homecare • vm) ^Ns. x Rex Wellness 

Special'^'* r,: ~^\. >^ Cenle 

Rex Obstetrics 
Cnainarr J Gynecology 

^^°"'"9 NC Kids of Raleigh 



/. 



RALEIGH 




^ 



Rex Healthcare of Cary 
Rex Family Practice of Cary 
Rex Pediatrics of Cary 
Rex Urgent Care of Cary nauFo 

Rex Wellness Center of Cary """"'='' 7o 



CLAYTON JOHNSTON 



Sarifo'r; Scecifli 
Clinics 



\ Game' 
\ Prac 



Farr.ily 
Practice 



Match Day 2000: 



Match Day. That annual event when 
medical school seniors nationwide learn 
which residency program they will enter. 
This year's event was held on March 16 
and approximately 140 graduating UNC 
medical students filled the Clinic Audito- 
rium. 

"As a group, our students arc incredibly 
accomplished and talented people, and 
Match Day is just one more manifestation 
of their achievements," said Georgette 
Dent, MD, associate dean for student 
affairs. 

"Traditionally, our students have done 
very well with regard to getting good resi- 
dencies; last year, the percentage of our 
students who got their top choice was 
higher than the national average," she 
added. "That says UNC is doing a great 
job educating these students, and as a re- 
sult, they are considered excellent recruits 
by other programs." 

About 86 percent of UNC medical stu- 
dents were matched with one of their top 
three choices during the computerized 
process. Sixty-four percent received their 
first choice. 




John Yiuini; (rli^hij. xluircs his lellcr with friends. 




2000 Residency Target Placements 
Specialty Placements 



Johnailian Bradley Woods Is all smiles on Mateh Daw 
14 



Family Practice 




■■^^^ 


^^m "> 




Inicrnal Medicine 








2* 


Medicine-Pedialncs 


■■■ -f 








Obsietrics/Gynccolog)' 




8 




Pediatrics 




^^^^^^ 






^^^^^^ 






Anesthesiology 




■ 7 




Dermatology 


■i 2 






Emergency Medicine 




8 




Neurological Surgery 
>, Neurology 


■ l 
1 






-^ Orlhopcdit Surger>' 




■ 7 




,^ Otolaryngolog>' 
% PM&R 
H Patholog)' 
Plastic Surg- Preliminary 
Plastic Surgery 


^^ 3 

1 
■ 1 

1 






Psychiatry 








Radiolog\ -Diagnostic 

Radio logy -Oncologic 

Surgery-General 

Surgery-Preliminary 

Urology 
Deferred 


hi II 


6 






3 


10 
Numf 


15 20 
cr of Seniors 


25 



'The World Is Your Oyster' 



By Lynn W'ooten 

The world is your iiNster. 
So it is. pertiaps. fitting that as the> 
prepare to head off on their own 
into their chosen professional 
world. UNC medical students recei\e a 
feu pearls. 

Pearls of w isdom. that is. 

Continuing a long and much-anticipated 
tradition. School of Medicine facult\' of- 
fered helpful hints, special reminders and 
often-touching ad\ ice to students at the an- 
nual Pearls Day gathering. 

Through skits, slide shows and simple 
heart-to-heart orations, faculty ga\e stu- 
dents a feu things to think about as the\ set 
out to become physicians theinseK es. Their 
"pearls" ranged from the serious to hysteri- 
cal, but no matter what the message, each 
facultN member received heart\. apprecia- 
tive rounds of applause from their soon-to- 
be fonner students. 

■Among the "pearls" offered for consider- 
ation uere: 

Georgette Dent, MD. associate dean tor 



student affairs — L'sing special lighting ef- 
fects (uell. OK. flashlights ua\ed from the 
front rou ) and slides. Dent created her own 
riotous \ersion of the megahit TV game 
shou. "Who Wants to Be a Millionaire'.'"' 
But her game. "Who Wants to Be Board 
Certified'"" offered such mind-numbing 
questions as "Paroxysmal nocturnal hemo- 
globinuria is lypicall\ characteri/ed b\ an 
abnormalitN in which of the l'olKn\ ing'.'"" 
For assistance, contestant/ student Donald 
McLamb elected to "call a friend"" — 
Stephen Kiser. MD. professor and associate 
chair for medical education. 

John Thorp, MD. associate professor of 
maternal-fetal medicine — Thiirp focused 
on the importance of physicians making 
strong connections u ith their patients. "Sit 
dou n u hen \ ou talk to patients."" he said. "It 
gi\es the appearance of concern." 

.\nthony Meyer. MD. professor and di- 
\ ision chief general surgery — No matter 
u hat is going on in a physician"s life. Meyer 
pointed out. the doctor should not be 
distracted or negatively effected to the detri- 
ment of interacting uith patients. In other 



words, personal baggage should be leli out- 
side the door. "In patient caiv. the person in 
the forefront of \(iur mind shinild be the pa- 
tient, not \ourselt " 

Anthony Lindsey. MD. clinical associ- 
ate professor of general ps\ chialr\ and be- 
ha\ ioral medicine — L'sing photographs of 
de\oted UNC employees as his backdrop. 
Lindsey stressed the importance ot assis- 
tants, nurses and other support personnel in 
a physician"s life. He suggested that the stu- 
dents, once the) are on their ou n. alua\ s 
remember — and appreciate — u hat these 
people ha\'e to offer. 

Harvey Hanirick, MD. professor of 
communit\ pediatrics — Hamrick noted 
one of the greatest fears a physician has: 
Becoming the target of a malpractice 
lausuit. With apologies to Da\ id 
Letterman. he offered up the Top 10 Rea- 
sons to .Axoid a Malpractice Suit ("Worst 
of all. your family uill encourage 
you to go to law school."") and the Top 10 
Reasons You Might Get Sued l"^'ou"\e 
never been sued."") D 



2000 Residency Target Placements 
Primary Care Placements 







^ 




^r^ 


^^r^ 


m 




l^yp 




1 ^^^1 







I'dlrii III ( (ij'jHi'^i I It In. iiihl lliiillu I Rdhi ilsoii Wliilv tii/(n </ //>,■/(/ iiuniit iil on 
SUiuliDax. 



AHEC: Taking Medicine tc 




Naiuy Pfifcr. Ml), ciiul tliinl-ycar resident lllvti Wilkcrsaii review seheJule.s. 



To understand the partnership be- 
tween the UNC School of Medi- 
cine and the N.C. Area Health 
Education Centers (AHEC) Pro- 
gram, you really need to leave Chapel Hill. 

You might head to Asheville to the Moun- 
tain AHEC, or to Wilmington to the Coastal 
AHEC. You could travel to the Southern Re- 
gional AHEC in Fayettc\ ille, to the Charlotte 
AHEC. or to Wake AHEC in Raleigh. Head 
west out of Chapel Hill and the tlrsl AHEC 
you'll pass is in Greensboro. 

The AHEC Program and the School of 
Medicine share a mission to meet the health 
care needs of the people of North Carolina. 
Greensboro AHEC. like the other sites, pro- 
\ ides the School with the resources to offer 
community-based training to medical stu- 
dents and residents and to provide profes- 



sional support and continuing medical edu- 
cation for physicians in the communities 
where they practice. 

Greensboro AHEC offers residenc\ place- 
ments in family medicine, pediatrics and 
internal medicine. The residency programs 
are sponsored by Moses Cone Healthcare 
Svsieni in conjunction with the L'NC School 
of Medicine. 

The program in internal medicine accepts 
20 residents and provides opportunities to 
learn in an environment that emphasizes the 
generalist skills necessary to enter a commu- 
nity-based practices. Residents function as 
primary-care physicians w ho deliver conti- 
nuity care for both inpatients and outpatients. 
Residency faculty members pio\ ide this edu- 
cation with e\tcnsi\e support from commu- 
nity preceptors 



The AHEC Program addresses the short- 
age and maldistribution of health-care pro- 
fessionals in underser\ed regions and 
encourages students to practice in those areas 
bv allow ing them to train alongside mral and 
communilN practitioners. AHEC also pro- 
vides informaliim resources and prolessional 
support that rural physicians need to stay on 
the culling edge of medicine. Since the N.C. 
AHEC Program began, nearly ."i.^S family 
doctors trained in AHEC-based residency 
programs ha\e settled in communities across 
North Carolina. 

"The moie students we tram in communi- 
tv-based settings and the more we support 
existing rural practices, the more attractive 
and better those practices become." 
said Thomas Bacon, DrPH, Director of the 
N.C. AHEC Proeram and Executive 



s[orth Carolina's Communities 



Associate Dean. 

The AHEC projiram began in 1972. It was 
one > ear later that Stew art Rogers. MD. grad- 
uated fnini the School. Rogers, a tenured lac- 
ult\ member at L'NC. has v\orked in internal 
medicine through Greensboro AHEC for 2 1 
years. Rogers belie\es one way AHEC im- 
proves health care in communities is by cre- 
ating an academic presence in the slate's 
hospitals. 

'AHEC bnngs t'acults and their talents as 
resources." he said. "The presence of medical 
student training programs and residencs pro- 
grams like we ha\e here in Greensboro gi\e 
practicing ph\sicians the opportunity to 
teach and sta\ connected w ith schools of 
medicine." 

Rogers places great \alue on his ov\ n com- 
munity-based rotation as a medical student. 

"\h familN is from Greensboro, and I was 
excited to he an acting intern in pediatrics at 
Moses Cone. I enjoNed it a great deal." he re- 
called. "I especially appreciated the indepen- 
dence ol doing meaningful clinical work 
awa\ from the uni\ersity." 

.\anc\ Pilfer. MD. 'S7. also is a full-tmie 
laculty member for the internal medicine res- 
idency program in Greensboro. A nati\e of 
Morganton. she completed three community 
rotations as a student. And like Rogers. Pfifer 
valued the hands-on nature of the rotation 

"I lo\ed it. mostly for the one-on-one ex- 
perience with the attending." she said. "I re- 
member once during my OB rotation at Wake 
AHEC. I got to do nine deliveries in one 
night. My peers back on campus didn't gel 
any w here near that kind of exposure. " 

illy a Wilkerson is a third-year resident in 
Greensboro's internal medicine program and 
has trained w iih both Rogers and Pfifer. A na- 
tive of Eden, he graduated in IW7 and rates 
his experiences w ith AHEC as "wonderful. 
My community rotations and residency pro- 
vided me with practical experiences where 
the attending phvsicians were verv approach- 
able and students were a prioritv." 

Besides his rcsidencv. V\ ilkcrsdii complet- 
ed a family practice rotation at Southern Re- 
gional AHE:C and an OB and emergencv 
medicine rotations at Wake AHI.C. and com- 
pleted thml-vear medicine inpatient and (uil 




patient rotations and a lourth-vear acting in- 
ternship at Greensboro AHIX" laniilv \Iedi- 
eine Clinic. 

Wilkerson plans to practice medicine in 
the Greensboro region. He plans to rely on 
AHEC for resources necessary for this new 
phase of his medical career. 

"I haven't felt any disadvantage working 
in Ihe communitv and a distance from Ihe 
School." he said. "I can relv on AHEC librarv 
resources during the ilay or night. .As long as 
I'm in the stale. I'll take advantage of all ihe 
serv ices AHl:C prov ides." 

Those resources are one ol the reasons the 
AHEC ProL-ram is so suecesslul. Ko.jcrs 
said. 

"It's easy uiulei ihe pressures ol private 
practice for phvsicians lo lose louch w ith the 
education process. " he said. "I think manv 
private physicians are grateful for ihe first 
class library resources, continuing education 
programs, off-campus degree programs for 
mid-level health-care professionals and the 
many other resources .AlliX" brings to the 
communitv " 

Besides piovulmg prolession.il support, 
the School ol Mi-dkineaiul Alll.Caic iin 



poilanl partners in palieiil education as well. 
Wilkerson said. 

"Ediiealing the palienl is a big part of the 
battle in improving healtlicare outcomes." he 
said. "With access to .AHEC libraries and 
their online resources, information from 
teitiai V research centers comes into commu- 
nities m verv expeditious fashion. .AHEC 
improves health care bv iinprov ing access to 
practitioneis. bin also bv providing 
educational programs loi prolessionaK and 
their palienis." D 



Kids at UNC Hosp 
To Talk With O 




Allwdii Sillier nt Rccivcitiaiuil Therapy liclps n puiicni upcniic STARBRICjHT. 



By Melissa Matson 

Imagine thai you're 1 2 years old and 
have cancer. Trips to the hospital lor 
chemotherapy are wearing you out. 
You're in pain and afraid of what \s ill 
happen to yi>u. On top of that, you feel like 
Nou're the only one in the world going 
through this. 

Now imagine sitting at a computer and 
talking face-lo-face with a 12-year-old can- 
cer patient in another state. He tells you he"s 
going through chemotherapy too. and like 
vou. is really sick. He"s also scared that he 
won't get well. '\'ou'\e found a friend. 

Children at UNC Hospitals are doing that 
through STARBRIGHT World, a prixate. in- 
teracti\ e computer network for hospitalized 

18 



children. The brainchild of film producer and 
director Steven Spielberg. STARBRIGHT 
World began in \^n5. Spielberg's idea was to 
enable sick kids to interact \ia \ ideoconfer- 
ence with other children facing similar health 
challenges. 

•■We have created a true \ irtual pla> ground 
— a place that can help children recapture 
the joy of being a kid. Regardless of how far 
technology ad\ ances. it is the human connec- 
tion that matters." said Spielberg, chairman 
of the STARBRIGHT Foundation. 

Last summer. UNC Hospitals became the 
first hospital in the Southeast to join the net- 
work. The day was celebrated w ith much 
fanfare, including a \ isit from the late 
N.\SCAR driver Adam Petty, who donated 
iiKinev to the project. 



Since then. STARBRIGHT World has re- 
ceived ra\e re\ iew s from UNC's pediatric 
patients. 

"The kids love this." said Allyson Salier. a 
recreational therapv assistant in charge ot 
UNC Hospitals' STARBRIGHT World. 
"The first thing the\ do when they come for 
return hospital visits is ask me when they can 
siet on STARBRIGHT." 

Currenth. UNC Hospitals has five STAR- 
BRIGHT World temiinals — one in its pedi- 
atric plavroom. I'ne in the N.C. Javcees Bum 
Center, one in the Hospital School, one in its 
pediatric hematologv/oncologv unit and one 
in the bone marrow transplant unit. 

■When the new N.C. Children's Hospital 
opens, we hope to have additional comput- 
ers." said Salier. "We plan to w ire every inpa- 



als Use Computers 
ler Sick Children 



Sprint teams with the 
STARBRIGHT Foundation 



These duN s. many busi- 
nesses look beyond profit 
margins to how they can 
participate in and 
strengthen the communi- 
ties around them. Spnnt is 
just such a company. 

So when the STAR- 
BRIGHT Foundation 
went looking for a 
telecommunications com- 
pan\ to help create STAR- 
BRIGHT World. Sprint 
stepped up to the plate. 
Now. Sprint is STAR- 
BRIGHT World's exclu- 
si\e telecommunications 
pro\ider. 

That means that Sprint 
donates the multi-million 
dollar network infrastruc- 
ture that enables thou- 
sands ot children to 
simultaneously e-mail 
each other: to see and 
speak w ith their peers any- 
where on the network 
through \ ideoconferenc- 
ing; to play together in 
real-time through interac- 
t:\c computer games; and 
to understand more about 



their illnesses through 
multi-media educational 
programs. 

The technology, called 
.As\ nchront)us Transfer 
Mode (ATM ) network, 
makes fast, secure data 
transmission possible. 
The result is that 100 hos- 
pitals can simultaneously 
send and receixe data, 
voice. \ ideo and sophisti- 
cated programming. 

Sprint is a global com- 
munications companv 
working to integrate long 
distance, local and wire- 
less communications ser- 
\ices. Sprint built and 
operates the United 
States" first nationwide 
all-digital, fiber optic net- 
work and is a leader in ad- 
\anced data communi- 
cations services and is 
a leader in advancctl 
data communications scr- 
\ices. Sprint has SI7 bil- 
lion in revenues and 
serves more than 17 mil- 
lion business and residen- 
tial customers. 




patients. 



r\ jhiiudiir Willi pcduilrii. 



lient r.Kim lor STAKBKIGHT World.' 

Besides its \ ideoconference capabilities. 
STARBRIGHT World offers video games 
and Internet access to 4(K) pre-approved Web 
sites. Children can find infomiation on a va- 
riety of illnesses, tests and treatments, or ihev 
can forget health issues altogether and play a 
game for fun. 

VV'hen Salier sits dovMi with a peiliatric pa- 
tient at a STARBRIGHT World computer, 
she's neverquite sure what will happen. 

"I let the kills go where they want and do 
what thev want wilh STARBRIGHT," said 



Salici. "It's important for them to feci that for 
a short lime during their dav. thev have some 
control."" 

Through .STARBRIGHT World, kids can 
also post questions like "What's ihe worst 
part of chemotherapv .' " on a medical 
bulletin board. Or they can search lo see w lio 
IS online. 

"I was with one 17-v ear-old who luul |usi 
been diagnosed with cancer. " said Salier. 
"When he sat down, the tlrsi thing he did was 
look up his tvpe of cancer. Then he ran a 
search lo tiiul sonieoiic aroiiiul his .rje who 



had alreadv lost their hair."" 

Rveryone involved with .STARBRIGHT 
World at IJNC Hospitals — from the doctors 
to the recreational therapists to the patients 
themselves — have come awav praising 
the sv sieiii, 

■Ourevpcrience is ihat STARBRIGHT 
World allev iates some of the an.xiely and fear 
children feel in the hospital."" said Harvey 
Hamrick. Ml), professor of pediatries. 
"We are so |ilcasetl lo be able to offer it to 
oui palieiils." n 



19 



Faculty Profile 



Harvey Hamrick, MD: 




Hiinc\ Ihiiinick cxcuuinvs Jciiiufvi- Rnullcx. 7. aj Snow Ciiiiip. NC 



K\ Lviin W'ooten 

As one (it L'NC's best-known and 
icspected pediatricians. Harvey 
Hamrick, MD. obviously has a 
way with children. As it turns out. 
he has a way with words, as well. 

"One of the things that stands out about 
Di-. Hamrick IV>r the residents and students 
training w iih him is his speech mannerisms."" 
says Alan D. Stiles. MD. acting chair ofthe 
department of pediatrics. "He frequently in- 
corporates "sayings" in his teachings that I 
am sure date from his childhood in western 
North Carolina. Forexample. he"ll say some- 
thing like. 'It looks like the chickens have 
come home to roost." when a diagnosis has 
been closed in on. One of our past residents 
assembled many of these to share at a depart- 
mental 'jaiheriniz. Evervone there could re- 



member situations where these were used."" 

In fact. Hamrick has left such a big im- 
pression on many of his colleagues, patients 
and friends throughout his years at UNC that 
he was recently recognized vv ith the H. Flem- 
ing Fuller Award, given annually to someone 
whose ov\ n dedication to the highest stan- 
dards of patient care and community service 
minor that of its namesake. 

"Receiving the Fuller Av\ard was reallv 
something."" Hamrick sav s. "I was qLiilc 
moved."" 

The recognition is a highlight in a career 
admired by others and relished by the 
avvard"s recipient. "I've just had a great Jour- 
ney here."" Hamrick say s. 

Hamrick was born in the small western 
North Carolina town of Rutheifordton. in the 
Ashev ille and Shelbv v icinity. Considering 
his famiK hisiorv. it was somethini: of a sui- 



prise thai he went into medicine. 

"I should have been a lawyer."" he recalls 
with a laugh. "Lawyers go way back in my 
family. I wanted to do something different, I 
think. There was no epiphany, if you will. 
There was no great calling. In deciding what 
to do. I looked for a challenge and something 
about medicine attracted me."" 

Hamrick graduated from UNC in 1961 
and entered the Navy. At that point, he says, 
"I wasn't sure v\hat I wanted to do."" Once the 
medicine bug bit. he entered the UNC School 
of Medicine and graduated in 1967. It was 
during his third year of medical schoi)l that 
he decided pediatrics was for him. "It just 
seemed to fit."" he says. ""I like working with 
children. And pediatricians are generally 
low-key people who have a lot of patience."" 

From 1 97 1 -72. Hamrick was in private pe- 
diatric practice in VV'inston-Salem. but UNC 



20 



Best-Loved Pediatrician' 



- and the idea ofteaching - drew him back to 
Chapel Hill, w here he's remained e\ er since, 
working and teaching as a pediatrics general- 
ist. "1 had ai\\a\s wanted to teach and felt so 
comfortable in this setting." he says. "1 like 
watching \oung people discover things 
themsehes and see their self-confidence 
grow, ^'ou can almost measure it b\ the 
month." 

"I ha\ e not regretted coming back here." 
.According to his colleagues. 
Hamrick"s students are glad he made that ca- 
reer mo\e. as well. "Dr. Hamrick generates 
enthusiasm about an\ clinical problem he en- 
counters in a patient - regardless of how rou- 
tine - and can infect the resident or student 
with that enthusiasm." sa\s .Stiles, who was 
one of Hamrick's residents in the I97()s. "l 
would say that Hamrick exemplifies w hat 
most of the pediatric residents in our depart- 
ment see as the pediatric generalist. He is 
also clearly the most popular role model for 
residents in the department." 

In fact, one colleague believes Hamrick's 
invohemeni in teaching - parlicularK his 
work in honing UNC's residencv program - 
IS what he will be best remembered for. "The 
e\cellence of the residencv program is his 



legac\." says Roberta Williams. MD. former 
chair of pediatrics. ""We ha\ e one of the nmst 
competitive training programs in the country. 
He has carelullv nurtmed the program and 
served as its best role model." 

Hamrick marvels at how medicine has ad- 
vanced over the past .^O-plus v ears. "Tech- 
nology has certainly changed - MRIs and CT 
scans are just amazing. And look at immu- 
nizations. For example, in the last 10 years, 
one of the most serious forms of childhood 
meningitis has been all but eratlicated bv an 
immuni/ation." 

But the evolution of the managed care 
trend troubles him. "HMOs have been verv 
disruptive of care." Hamrick says. ""The 
strong relationship between physician and 
patient has been fractured quite a hit bv that." 

While Hamrick does not work in the clini- 
cal setting as much as he once did. his pres- 
ence in the Held remains strongly felt. ""He is 
consistently diligent, compassionate, careful 
and unpretentious." Williams savs. "He 
maintains the highest standards of clinical 
care and expects the same of others. He ap- 
proaches problems with knowledge and w is- 
dom. hiMiiorand sensiliv itv." 

Now approaching fi(). and with main of 



Rcsidvni Riiiiiiiie hrluiri. /<■//. miJ Hamruk uilk will; .Icnnitcr Bnullcx of Snow C 



imp. 




his friends and colleagues hav ing alreadv re- 
tired. Hamrick understands that retirement is 
in the not-too-distant future. But the notion 
of hanging up his w hile coat leaves him a bit 
uneasy. Retiremcnl would allow him to bet- 
ter cnjov such favorite hobbies as swimming 
and spend more lime with wife .Ann; their 
two children. Anna, an allomev specializing 
in medical malpractice law. and James, a 
fourth-year LINC medical student heading to 
the L'niversitv of California at San Francisco 
for residency; their s|iouses: ami ;i new 
grandchild, his fust. 

"'I really don't leel like retiring." 
Hamrick says. ""Nol yet. But whatever I do. I 
w ant to be verv useful at it." 



The H. llemiiig liillei .Awartl is in- 
tended as a permanent memorial to 
Kinston physician H. Fleming Fuller, 
who died in 1986. A founding member 
ol the board of directors of North Car- 
olina Memorial Hospital. Fuller served 
on the board from 1971 until his death 
The l-"ullei Award is bestowed on some 
one based on these attributes: 

• Unwavering personal connnitment to 
treating patients w iih compassion and 
respect 

• Ongoing serv ice as a staunch advo 
cate for maintaining the highest stan- 
dards of patient care and well-being 
— both ]-)hv sical and emotional 

• Flffectiveness as a professional role 
model foi the siudents and voiing 
physicians responsible lor the cue ol 
future generations 

• .Sense ol civ ic res|ionsibiliiv through 
active participation in grou|-)s or orga- 
nizations concerned with the health 
and well being ol \oilh ('.Molina's 
cili/ens 

1 Ins V car's lecipieiil will be aiinounceJ 
Sepl'l.S 




Faculty 

Notes 



Christopher C. Baker, MD, FACS. pro- 
lessor of surger\. v\ as recently appointed to 
the Committee on Surgieal Education in 
Medical Schools for the American College 
of Surgeons. Baker also served on the Amer- 
ican College of Surgeons" Committee on 
Trauma and is currently a member of the 
Curriculum Committee for the Association 
for Surgical Education. 

Janice M. Dodds, Edl). associate profes- 
sor of nutrition, has re- 
eei\ed the Catherine 
Cowell Aw ard from 
the American Public 
Health Association's 
food and nutrition sec- 
lion, of w hich she is 
chair. The award, 
sponsored by Mead 
.lohnson Nutritionals. 
rect)gni/es excellence 
and achie\enient in 
administration, plan- 
ning, mentoring and team biulding in public 
health nutrition, and includes a cash prize. 
Dodds specializes in community-based in- 
ter\entions to imprme nutrition and studies 
leadership de\elopment with a focus on 
management in public health nutrition with 
women and children. She is also serving on 
the N.C. Institute of Medicine's child health 
task force as chair of the health promotion 
subcommittee. 

I)a\ id .\. (lerber, MD. assistant profes- 
sor of surgery, recenth recei\ed a Eaculty 
Research Fellow ship from the American 
College of Surgeons. Gerher will receive 
S.^5.000 annually for two years, during 
w hieh time he will be working on the isola- 
tion and identification of a hepatic progenitor 
cell pt>pulation. Further analysis will look at 
llie antigenicity of these cells and how this 
would impact their potential in li\ercell ther- 
ap\ as an alteniali\e to solid organ transplan- 
tation. 

Robert N. Ciolden. MD. professitr and 
chair of psychiatrv. has been appointed to the 
editorial board of Depression and Anxiety. 
Golden has also been appointed to a three- 
\eartenn on the Scientific .Advisory Panel of 
the .American Psvchiatric Institute for Re- 
search and Education. The Institute, an affili- 
ated organization for the American 
Fs\ chiatric .Association, is charged v\ ith es- 
tabhshuig the leadership role of the AP.A in 




IN REMEMBRANCE 

W. F'aul Bijijiers, .MD. 62. died April .S. 2( )()(). leaving 
a legacy as a caring physician and a teacher of physicians. 
He was an integral part of the University of Niirth Caroli- 
na since becoming a medical student in 1959. Dr Biggers 
completed his residency and joined the faculty in 1968. 
He offered an example of compassion, scholarlv devd- 
tion. ;ind commitment to patient care. 

Beyond these contributions. Dr Biggers had a lifetime 
interest in speech and language and served on the Board 
of Examiners for Speech and Language Pathologists and 
Audiology. Through tireless efforts, he ensured that the 
state Legislature established and continued a program 
designed to aid children with speech and hearing disor- 
ders. This program has already benefited thousands of children w ithin our state. 

For these elforts. he was presented the Service to Mankind Award and also was named 
the 1999 H. Fleming Fuller Award winner as the outstanding clinician at UNC Hi>spitals. 
(A profile about Dr Biggers appeared in the Winter 1999 issue of this publication.) 

In recognition of Dr. Biggers" many contributions. George Sheldon. MD. and 
Harold C. Pillsbury. MD. led etYorts to rename the Carolina Children's Communicative 
Disorders Program the VV. Paul Biggers. MD. Children's Communicative 
Disorders Program. 

Just w eeks prior to his death, the W. Paul Biggers. MD. Distinguished Professorship w as 
established. Dr Biggers requested that the Professorship be awarded to a physician who 
shares his passion for innovative teaching. Indiv iduals wishing to make a donation ti> the 
endowment of this new Iv created professorship should contact The Medical Foundation of 
North Carolina. Inc. at ( 9 1 9 1 966- 1 20 1. 



contributing to the scientific basis of psychi- 
atric practice and policv . 

Sharon Rin^^vvalt. MS. clinical assistant 
professor of sjieech and hearing sciences, 
has been appointed the Orange Countv 
Preschool Interagency Council's representa- 
tive to the board of the Orange County Part- 
nership for Young Children, for a three-year 
term. Ringwalt currentiv is the co-chair of 
the Health and Early Intervention Grants Re- 
vievv Committee for the Partnership. 

(;e()rj;e K Sheldon. MD. Zack D. Owens 
distinguished professor and chair of surgery, 
has been awarded an honoran fellowship by 
the Philadelphia Academy of Surgery, the 
oldest surgical society in America, for his 
contributions to the improvement of the sci- 
ence of surgery and the education of sur- 
geons. 

Sheldon has also been unanimouslv se- 
lected as an honorary fellow of the Society of 
Black Academic Surgeons. The classifica- 
tion of honorary fellow is the Society's most 
coveted recognition and is bestowed on 
those \\\w have distinguished themselves 
through outstanding achievement and dedi- 
cation to the objectives of the Society. 



Sheldon w as most recently elected as an 
honorary fellow of the Royal College of Sur- 
geons of England, an independent, profes- 
sional body committed to promoting and 
advancing the highest standards of surgical 
care for patients. He will be admitted to the 
College at a ceremony in October 

Sheldon, surgery ehainnan for 15 years, is 
the chair of the Association of American 
Medical Colleges, an organization dedicated 
to improv ing public health by enhancing the 
eflectiveness of academic medicine. He is a 
fomier president of the American College of 
Surgeons, the American Surgical Associa- 
tion, the American 
Board of Surgery and 
the .American Associa- 
tion for Surgery of 
Trauma. The author of 
more than 300 articles 
and book chapters. 
Sheldon has held edito- 
rial board appointments 
at several national 
peer-reviewed medical 
journals. Shchlcn 




Alumni 

Notes 



60s 



Marvin R. (ioldstein, MD '65. has been 
practicini: canJiolog\ in Scottsdalc. Ariz., 
for 30 \cars. He and his w ife. Michelle, 
crossed the Pacific and back (7.000 miles i 
in their sailboat. Upon their return. the\ 
found out they were pregnant with tw ins. 
now age two. Mar\ in can be contacted at 
iiiarx goldC« speedchoice.com. 

Benjamin K. Ward, Jr., .MD "67. w as 
named Rotarian Man of the Year in I9W by 
the Florence. .South Carolina Rotar\ Club. 
He is a urologist with Florence L'rologic 
.Associates. 



70s 



Cynthia I). Conrad. MI) '78. has a new 
position w ith Connecticut Valley Hospital, 
the state's long-temi psychiatiic hospital, as 
Chief of Professional Senices. 

Jonathan S Krauss, MD '78. recentl\ ac- 
cepted an earl\ retirement offer from the 
Medical College of Georgia where he has 
been a professor of pathologs'. 



80s 



Charles B. Nemen.fl. MD '81. PhD '76. 

was recently recei\cd the William C. Men- 
niger Award for contributions to mental 
health by the American College of Ph> si- 
cians. He will recei\e the award ne.\t 
.April in Philadelphia at the ACP's annual 
meeting. 

William Uinkenwerder, .MD "81. was re 

cently named to the Board of Directors of 
the .American Association of Health Plans 
and was elected fellow of the American 
College of Physicians. Fie currently ser\es 
as e\ecuti\e \ ice president and \ ice chain )f 
Blue Cross/Blue .Shieki of Massaclui sells. 

Mare Randall. Ml) -HI. iscuneniK chair 



and William A. Mitchell Professor of Radi- 
ation Oncology at Indiana University 
School of Medicine. This year, he w ill serve 
as the President of the Medical Staff of Chil- 
ian Health Partners Inc.. the consolidated 
hospital system of L'ni\ ersit\ Hospital. 
Riles Hospital tor Children and Methodist 
Hospital of Indiana Inc. Marc and his w ilc. 
Brabsie (BS "79). have three children: Ken. 
1 4; Morgan. 1 2 and Marycobb. 10. 

Tobia.s Schifter. MD "86. is a diagnostic ra- 
diologist and nuclear medicine specialist in 
Phoenix. Ariz. He recently was appointed 
president of the Arizona Radiological Soci- 
et\. His two-year term stalled Januars 2000. 
He can be reached at tschiftercp e\ di.iiet. 

Phil Thwing, MD '84. is engaged to be 
married to LeAnne Keicher. His email 
address is: PhilThw ing(?' Greene. xtn. net. 

Lawrence W yner, MD '83. is a renal trans- 
plant surgeon at Charleston .Area Medical 
Center in West Virginia. He and his w ife. 
Louida. announce the birth of their second 
child. Tessa Anneliese. who was born No\. 
,^0. 1999. Their son. Joshua Ross, celebrat- 
ed his third binhda\ in .luK. 



Fresno. He 
kin>:bibbvfe aol.( 



reached 



90s 



Brian Hamilton, MI) "91. moved to Ann 
Arbor. Mich., in 1991. where he completed 
his radiology residency and tellowships in 
cross-sectional imaging and interventional 
radiologv. In 1997. he moved to Charlotte, 
where he joined Mecklenburg Radiology 
Associates. He and his w ife. Kim. recently 
welcomed triplets (Lila. Oliv ia and Mc.Alis- 
terl to their familv. 

C. Kins Bibhy ,|r., .Ml) '92. finished iwo 
years as a general suigcrv rcsKlcnl al ['C- 
San Francisco belore complclmg familv 
practice residency at Medical College of 
Virginia in Richmond. Va.. and becoming 
boaril ceinlied in 1997. Bihby is now com- 
pleting his general surgery residencv at I 'C- 



Catherine C. Betor, MD '93. gave birth h) 
Nicole Canada Betor on Oct. 19. 1999. She 
works as a pediatric ophthalmologist w ith 
Morganton Eye Physicians. PA. 

Cynthia Cowan Bennett. MD '93. and her 

husband. Scott Bennett. Ml) 9.^ gave birth 
to tw ins. Ouentin Thomas and Oliv ia Judith 
on Nov. 23. 1 998. Bennett and her husband 
are in private practice in Gastonia and can 
be reached at cindv-louCn gndusa.net. 

N ictoria Carrett, MD "96. a lesident at 
Children's Hospital of Michigan, helped de- 
sign a program that recentlv receiv ed a 
Community Access to Child Health plan- 
ning grant, funded bv Wyeth Lederle Vac- 
cines and awarded by the American 
Academy of Pediatrics. The program, 
called Teaching Children How to Raise 
Children, is designed to give teen-aged 
mothers in Detn>it the skills ihev \kw\ lo 
care for their children. 



23 



Development 
Notes 



Dance Marathon raises 
$70,000 for Kids 

The second aniuuil LJNC Dance Marathon 
raised S7().()25.98 to henefit the patients of 
the N.C. Children's Hospital — nearl\ dou- 
bling its first-) ear collection. 

The Medical Foundation and ever>'i)ne at 
the N.C. Children's Hospital is extremely 
gratetul for the endless effort and enthusiasm 
gi\en by the participants of this year's Dance 
Marathon." said Jim Copeland. president of 
the Medical Foundation of North Carolina. 
Inc. "Their achievements are remarkable. 
They are a shining example of what Carolina 
students are capable of when they pull togeth- 
er for a great cause — children." 

The Dance Marathon is the largest 
fundraiser for the Children's Hospital and is 
organized solely by L'NC students. More than 
70 students danced for 24 hours beginning at 
7 p.m. Feb. 25 to raise money for the Chil- 
dren's Hospital. The Dance Marathon com- 
mittee has purposely left this money 
unrestricted because its members want it 
a\ailable for the programs and patients most 
in need. 

Last year, the Dance Marathon raised 
$40. 00,^.8.5 during its inaugural event, mak- 
ing it a first-time success story. Organizers 
this year broke last year's total in part b\ also 
hosting a silent auction of donated items. The 
auction alone brought in S 1 2.2.56. 

MAA Supports High-Tech 
Health Sciences Library 

L'NC's Health Sciences Library has 
received S4().00() from the Medical Alumni 
Association and its Medical .Alumni Loyalty 
Fund. This is the second pa\iiient of a fi\e- 
year pledge totaling $2()0.()()6. 

The pledge is a gesture of the Association's 
commitment to the Library's Capital Cam- 
paign, an initiati\e to renovate the library 
building to meet the changing needs of phy si- 
cians. faculty, staff and students in the 21st 
century. The Medical .Mumni Association 
has a history of supporting the Library . Since 
1 49 1 they ha\ e donated a total of S325.0()0 to 
assist the Library in pro\ iding inno\ati\e 
health information sy stems and ser\ ices. 

Campaign goals include creating teaching 




James Harper. MD. and Jane McNeer. 
Irii^liO. present Carol Jenkins with a $40JI(H) 
clicik far the L'NC Healtli Sciences Library. 

labs, an electronic classroom with teleconfer- 
ence capabilities and cutting-edge media 
kitchens, where students, library staff and 
faculty collaborate to make electronic course 
materials. The kitchens v\ ill contain all the 
necessary ingredients, such as network con- 
nections and digital \ ideo softw are. to create 
the most effective set of matenals for both the 
teacher and student. 

Though the renovation is not intended to 
prov ide increased space, it will offer users a 
redesigned space for learning and teaching. 
"We want to make the Library a warm and 
inv iting gathering place for everyone who 
takes advantage of our resources. At the same 
time, we need to be as high tech as possible," 
says Carol Jenkins. Health Sciences Library 
Director. 

Former UNC researcher 
honors his late wife with 
$1 million donation 

A fonner UNC researcher has given more 
than SI million to establish fellowships hon- 
oring his late wife. The fellowships would 
benefit future scientists with the UNC Neuro- 
science Center. 

James R. White. PhD. a retired UNC pio- 
fessor of biochemistry, has transfeiTcd stock 
valued at S 1 .028 million to The Medical 
Foundation of North Carolina, Inc., to fund 
the Helen Lyng White Fellowships in Neuro- 
science Research. 

■"Follow ing my vv ife's death. I tried to de- 
V elop a vv ay to honor her memory in an ap- 
propriate way." he said. "Since most ot 



Helen's research in the years just prior to her 
death w as directed toward the dev elopnient of 
drugs to treat afflictions of the central nervous 
sv stem, it seemed appropriate to somehow 
promote research in the neuroscience area. 
Fortuitously, at UNC-Chapel Hill the Neuro- 
science Center had just gotten underway." 
said White. 

"This endowment is a wonderful gift and 
sincerely appreciated by all of us at the 
School of Medicine." said Jane NL McNeer, 
V ice president of The Medical Foundation of 
North Carolina. Inc. "Many young scientists 
for years to come will be the true beneficia- 
ries. This gifi will make a real difference in 
research at the Neuroscience Center." 

James White met Helen Lyng w hile they 
were both doing research w ith the DuPont 
Co. in Wilmington. Del. Follow ing their mar- 
riage in January 1955. Helen, a 1952 graduate 
of Russell Sage College, continued her edu- 
cation at the University of Delaware, where 
she received a Master's degree in radiation 
chemistry . In 1 962. they came to UNC. w here 
James joined the faculty of the medical 
school. Helen received her PhD in biochem- 
istry in 1967. Thereafter, she Joined Bur- 
ixHighs Wellcome Laboratories. 

When Glaxo purchased Burroughs Well- 
come, she and other scientists fomied a com- 
pany called KPI, which is still located in the 
area and focuses on studying nerve grow th 
factors and antidepressants. 

Helen While died of cancer in 1997. 
■ ^"^^H William D. 

F ^^^MkJ^0 Snider. MD. 

director of the 
Neuroscience 
Center, said it 
"is anticipated 
that the inter- 
est from this 
endow nient 
would support 
TK^^ the salaries of 

"^^ two post-doc- 

toral fellows. 
The success- 
ful applicants 
would bear the title "Helen Ly ng White Fel- 
low in Neuroscience Research." 




Helen Lxni; White 



President's 
Letter 



Final Grcetiriiis. 

li has been an honor and a pleasure to 
serve as president of the Medieul Alumni As- 
stx:iation this past year. I ha\e enjoyed nian\ 
opportunities to partieipate in \arious eere- 
monies and meetings that in\ol\ed alumni, 
faculty, students and friends of the medical 
school. 

At the White Coat ceremon\ and at gradu- 
ation, it was a treat to share the excitement 
and anticipation of students at the beginning 
and the end of their school experience. These 
are some impressi\e young people about to 
enter the profession who will be a credit to 
their alma mater. 

The N'omia Berrxhill Lecture brought to- 
gether many longstanding and new faculty 
and friends to he reminded once more of the 
rich heritage we share though our school. 

Regional alumni meetings were well at- 
tended and w ere a time of fellow ship and an 
opportunity, for Dean Houpt to discuss the 
state of the school. I'm sure those who made 
the effort to attend were gratified b\ the expe- 
rience. 

My favorite e\ent is the Spring Alumni 
Meeting. The turnout this year was outstand- 
ing. Aside from my being somewhat micro- 
phone-challenged, the program went well. 
The recipients of the .Alumni Distinguished 
Service Awards certainlv represented the 
best that the School oi .Medicine stands for. 
Presenting Harold Roberts the .Mumni Dis- 
tinguished Facull\ .Award was the highlight 
of the Near tor me. Ron Neal's remarks in an- 
nouncing the scholarship endowment in Dr. 
Roberts" honor epitomized the sort of impact 
he had on many who trained and vsorked 
under him. 

Dr Bud Harper has ccrtaiiil\ taken on his 
duties as .Associate Dean for Alumni Affairs 
with relish and finesse. (As an aside, compar- 
ative golf scores of Dr. Harper and Dean 
Houpt are a state secret I) Of course. 
Stephanie Stadler makes the alumni office 
runassmoothl\ as it does 

Acknowledgments would be incomplete 
without thanking John hnisi. abl\ supporteil 



b\ the .Medical Foundation Stall, tor his un- 
relenting efforts on behalf of the Lo\alt\ 
Fund. Congratulations are in order to the 
Class of '.SS for their outstanding contribu- 
tion this \ ear 

For our school to continue to progress and 
prosper the referendum on the bonds tor cap- 
tial projects in the uni\ersit\ system must 
pass. .Anyone v\ho will speak on behalf of the 
bonds at ci\ ic clubs, churches, etc. can con- 
tact the Dean's otTice for speaking points or 
other assistance. "\'our help is needed. 

Finalh. thank you for >our support this 
\ear 1 know \ou will enjo> having Paul Viser 
at the helm in the next year 

GonhmBLiCnmJ.MI). Vo 




-« »vx' 




ME/Alumni Calendar 



June JO, 2000 - Chapel Hill 

McdiLcilcL'al Semiiuir 2()()() 

June II, 2000 - Chapel Hill 

Palhology aiul Laboratory Medicine Update tor the Praeticint; 
Patlioloyist 

June 16, 2000 - Chapel Hill 
Ol'RR Regional Worksliop 

Julv 7-10, 2000 - Chapel Hill 

IJeiiientary & Adoleseenl IHACCII Summer Trainini; 

July lO-Aug 4, 2000 - Chapel Hill 
Preschool TKACCH Summer Trammt; 

Jul\' 21-23, 2000 - Amelia Island. FL 

Heart F-aikire Maiiagemeiil 2()()1) 

Julv 21-23, 2000 - Research Triangle Park, NC 

Neurode\elopmeiital Variations 

Julv 10- August 4. 2000 - Chapel Hill 
Preschool TEACCH Summer Traming 
Hlementary & Adolescent THACCH Summer Training 

I-or more information about CME courses, contact the Ot'fice 
ot Continuing Medical Education. (919) 962-21 18, or toll-l'ree 
through the Consultation Center. (800) 862-6264. To contact 
the Alumni Affairs office, call (919) 962-6786 ore-mail 
medical alumni C"' med.unc.edu. 



Estate Planning Notice 

Many individuals would like to make a major gift 
to the UNC medical center, but cannot commit 
current assets for such a purpose. Through a will, 
however, anyone can make a more significant gift 
than they might ever have thought possible by 
designating a specific sum, a percentage, or the 
residue of their estate for the benefit of the medical 



To provide a bequest, simply include a paragraph 
in your will naming The Medical Foundation of 
North Carolina, Inc. as a beneficiary. For example: 

"I give, devise and bequeath (the sum of$ , 

or ( % of my estate) or (the residue of 

my estate) to The Medical Foundation of North 
Carolina, Inc., a 501(C)(3) created to maintain 
funds for the UNC medical center with principal 
offices located at 880 Airport Road, Chapel Hill, 
North Carolina." 

This language creates an unrestricted bequest for 
use by the medical center when and where the need 
is greatest, or you may specify that your gift be 
used for a particular purpose. 

For further information on bequests, contact 
Jane McNeer at (9 1 9) 966- 1 20 1 , (800) 962-2543, 
orjmcneer@email.unc.edu. 



Nonpi-Dfit Organization 

U.S. Postage 

PAID 

Chapel Hill. NC 

Permit No. 24 



PERIODICALS DEPARTMENT 
HEALTH SCIENCES LlBi^ARY 

CAROLINA CAMPUS 7585 



Summer :(HM) 



Medical Alumni 



BULLETIN 



School of Medicine, University^ of North Carolina at Chapel Hill 




W Reece Berryhill, MD 

The Father of 

Modern Medicine 



Walter Reece Berryhill, MD 

lOOth anniversary of his birth stirs memories of enormous contiibutions to UNC 



By Karen Stinneford 

Nearly tour decades after Waiter 
Reece Berryhill. MD. stepped 
dow n as dean of ttie UNC Sciiooi 
of Medicine, his \ ision and intlu- 
ential leadership li\es on. 

It is evident in the initials ""MD" that ap- 
pear on Carolina diploma's behind e\er\ 
medical school graduate's name. 

It is evident in patients from towns such as 
Grifton and Monroe and Hamlet who ha\e 
access to high quality care at one of the coun- 
try's finest academic medical centers. 

It is evident in the hundreds of doctors, 
nurses, pharmacists and dentists working in 
medicalK underscrxed areas of the state with 
the support of the N.C. Area Health Educa- 
tion Centers program. 

.As stated b\ one of Berryhill's fonner stu- 
dents and faculty members in a letter nomi- 
nating his mentor for the Universitvs 
prestigious O. Ma.x Gardner Award. "Dr. 
Berrvhill has always seemed to me to exem- 
plify the characteristics of one who has done 
most to benefit the human race." 

Berryhill. the architect of modem medical 
education at Carolina, was born near 
Charlotte on Oct. 14. 1900. 

.A staunch Scotch-Presbyterian. Berryhill 
intended to pursue a career in the ministry 
when he enrolled at Carolina in 1917. Figur- 
ing a minister needed to be well-grounded in 
the classics, he studied Latin. Greek and 
English, even w inning the Eben Alexander 
Prize for the best English translation of a se- 
lected Greek passage. With characteristic hu- 
mility. Berryhill later downplayed the 
achie\ement by saying the prize wasn't a big 
deal — he w as the only student who compet- 
ed for it and besides. "I needed the S 1 0." 

But modestv can't hide the accomplish- 
ments of a young man determined to make 
the most of his education. During his under- 
graduate years at Carolina. Berryhill ser%ed 
as president of the senior class and head of 
the student council and was inducted into Phi 
Beta Kappa. 

Sometime during his junior \ear. Berryhill 
decided to become a doctor instead of a min- 
ister. He also met the woman w ho would be- 
come his w ife and. years later, his partner in 




Waller Recce Bcriylull. MD 

\,<nh C,m,lm,l Colic, lun, I 'mveism nl ,V..;1/; Cun^lliui Uhuii-. al Cluipcl llil 

building the medical school and hospital at 
UNC. ^ 

Benyhill met Norma Connell of Warren- 
lon one Saturdav afternoon at Peace College. 
He had gone there to \ isit a girl from home, 
but upon finding her holding court with a par- 
lor-full of male suitors, he was introduced in- 
stead to Miss Connell. who accompanied 
him to the college chapel for a chat. 

During their visit. Berryhill proceeded to 
shock the pious young lady w ith questions 
that seemed heretical. "Could God fry an egg 
on a snow ball'.'" he asked her. 

"He didn't have the gift of gab. and I didn't 
ha\e the gift of gab. and he just trying to find 
something to say." Mrs. Berryhill recalled re- 
cently. "He was trying to shock me to start 
the conversation and so he borrow ed a tech- 
nique from Horace Williams, his philosophv 
teacher, who would ask shocking questions 
to make people think and talk." 

When he graduated from Carolina in 
192 1 . Berryhill lacked money for medical 



school, so he returned to Charlotte and 
taught in local public and private schools 
for two vears. carefulh sa\ ing for a retum 
to Chapel Hill. 

Since it was founded in 1S79. closed in 
ISS.'^ and re-opened in 1890. the UNC 
School of Medicine had struggled to ex- 
pand its curriculum beyond a tw o-year pro- 
gram of gross anatomy instruction and 
science labs. In 1902. the University's lead- 
ers added an additional two years of clini- 
cal instruction by tapping the resources and 
patients in several Raleigh hospitals. The 
effort failed for lack of state funding and by 
1910, the University was back to teaching 
the basics in a two-year program. Its med- 
ical students had to attend other colleges to 
procure their medical degrees. 

Berryhill received his medical degree 
from Harvard in 1927 and was an intern 
and resident in medicine at Boston City 
Hospital before mo\ ing to Belmont for a 
short stint in priv ate practice. 

In 1929-30. he pinch-hit in the class- 
room of Isaac Manning. MD. dean of the 
UNC School of Medicine. When Manning 
asked Berryhill to teach a physiology 
course, the latter replied that he didn't 
know enough physiology to conduct it. 
"Well. Reece. then this is a good way to 
learn some more!" Manning responded. 

Whate\ er his initial qualms about teach- 
ing. Benyhill clearly had the gift of — and 
love for — classroom instruction, and from 
that point on practiced medicine in an acade- 
mic setting. 

Berryhill and Miss Connell married in 
August 1930. and she accompanied him to 
Cleveland where he was first chief resident in 
medicine and later attending physician at 
Lakeside Hospital and an instructor at Case 
Western Reserve University. The Berryhills 
returned to North Carolina in 1933 when he 
accepted a position as chief physician at 
UNCs student infirmary. A short time later, 
he became an associate professor of medi- 
cine. 

Bern hill rose quickh through the ranks of 
the medical school, becoming assistant dean 
in 1937 and acting dean in 1940. When he 
became dean in 1941. he was just 41 years 
old — the youngest man ever appointed to 



the position. Mn _\ outh didn't impede his \ i- 
sion. Legend has it Bern hill so belie\ed Car- 
olina needed a four-\ear. degree-awarding 
medical school that he extracted a promise 
from then-Uni\ersit\ president Frank Porter 
Graham to help make it happen. 

Bern hill's timing — that ot World War II 
— would pro\e pro\ idential. .At the same 
time Berr\ hill began his et't'ort to expand 
UNC's medical school, men throughout 
America were enlisting in the armed ser- 
vices. North Carolina men were called to 
serve, too. but many were rejected as being 
physically unfit. The state ended up w ith one 
of the nation's highest draft-rejection rates. 

Why w ere North Carolina men — many of 
whom toiled in the strenuous labor of farm 
and textile work — physically unfit for 
armed sen ice' Poor nutrition w as one cause, 
but a bigger factor w as access to got)d med- 
ical care. Being a predominantls rural state. 
North Carolina lacked enough phvsicians to 
adequatelv care for its population. As a re- 
sult, many injuries and illnesses went un- 
treated, vshich affected the overall health of 
the state's citizens. 

The embairassment of ha\ ing one of the 
countrv 's worst draft-rejection rates spurred 
North Carolina's legislature to create seseral 
commissions and public-ser\ ice campaigns 
to promote better health. This otfered Berrv - 
hill the perfect opportunity to sell his \ ision 
of what the state's tlagship university could 
do to for her citizens: train more primarv - 
care doctors w ho. in turn, could treat more 
people. 

To accomplish this. Berryhill said. Caroli- 
na needed a four-year medical school. 
Carolina needed a hospital 
where medical students 
could gain \aluable clinical 
experience and where com- 
munitv -based ph\ sicians 
could send their patients tor 
specialized care. .And Car- 
t)lina needed to encourage 
medical students to work in 
small-town practices, and 
also lend support to the 
physicians alreads serving 
there. 

His \ ision became the 
blueprint forlodav's L'NC 
.School of Medicine. I'NC 
Hospitals and the N.C. Area 
Health lulucation Centers 
program. 

William B Blsthe. MI). 
Marion Covington profes- 
sor of medicine, called 
Berryhill's timing fortu- 
itous. Not onl) was the .N.C. 
General Assembly con- 
cerned about the poor health lhi\ lu\i,iiii 
of citizens, but mans men in / nivcisin \ 



political pow er w ere former classmates ol 
Bern, hill's. The\ quicklv embraced his opin- 
ion that the University should be part of the 
solution. 

■'In the m4()s. the leadership of this state, 
bv and large, had come from Carolina — 
they were Berryhill's schoolmates, and that 
■good old boy' network helped him iremen- 
douslv." Blv the said. 

In I'-UV. the General .Assemhiv provided 
S5. 240. ()()() to build a 4()()-bed hospital in 
Chapel Hill. The money also was used to ex- 
pand the School of Medicine building and 
build domiitories for nurses and house physi- 
cians. Two years later the General Assembly 
appropriated another $2.3 million to com- 
plete these projects. 

In an undated op-ed column Bcrrv hill 
w rote shortlv before N.C. Memorial Hospital 
opened in 1952. he lauded how these im- 
provements would benefit all North Carolini- 
ans. 

"With this increase in the annual output of 
doctors, largely residents of the state; with in- 
creased facilities for the training of nurses, 
technicians and aides in various medical 
fields: and vv ith increased consultation and 
postgraduate education facilities available, 
the state should be well along the road toward 
solv ing its most pressing health problem — 
the lack of adequate personnel." he stated. 

The UNC School of Medicine graduated 
its first class of MDs in 1 954. 

While Berrvhill carefully built a medical 
school and hospital in the 195()s and early 
196()s. he did so without any fanfare or self- 
promotion. Indeed. Berryhill's inodesty and 
humilitv vvas renowned anions; students and 




facultv. Even the most comprehensive book 
to detail the history of the L'NC School of 
Medicine. "Medical Education at Chapel 
Hill: The Eirst Hundred '\'ears." barelv men- 
tions BeiTvhill and his legacv at all — a tact 
that seems strange until one happens to note 
he w as an authoi'. 

"Dr. Berrvhill had a strong devotion to 
dutv. vshich was manifested in a strong devo- 
tion to the L'niversitv of North Carolina and 
to the state." Blv the said. "The University 
and the medical school were his religion — 
he had no desire for self-pre)motion and he 
never took credit for anv thing. He just want- 
ed what was best for the l'niversitv and med- 
ical school." 

William W. McLendon. MD. emeritus 
professor of pathologv and laboratorv medi- 
cine, said Berrv hill possessed a number of 
characteristics that made others admire him 
as a leader His ability to carefullv listen to 
and weigh other peoples' opinions before he 
made a deliberate and final decision com- 
manded respect. He knew everv' faculty 
member and student bv name. He sought out 
faculty meinbers w ith strengths different 
from his ow n and gave them the autonomy 
the\ needed to fulfill their professional po- 
tential. 

Most of all. Berrvhill possessed enonnous 
personal and professional integrity, said 
McLendon. who recounted the following in- 
cident: 

"One day. Dr Berrvhill got word that his 
barn w as on fire." McLendon said. "He had 
the keys to the state car in his pocket because 
he was going to Raleigh that afternoon to ap- 
pear before a legislative study commission. 
No one would have 
blamed him for jump- 
ing III the stale cai and 
dri\ mg oul to sec 
about his burning 
barn, but Or BeiTvhill 
wouldn't have even 
coiisuieicd doing 
that. Instead, he 
w a Iked around the 
medical school until 
he found a lacullv 
memlx'i whose car he 
could bniidw ami 
ihcii he iliovc the bor- 
row cd car niii 111 ihc 
bain " 

I'hvsicians like 
Berrvhill who trained 
during the I92()sand 
1 9.^()s were encour- 
aged to develop im- 
|iosing. stem 

countenances to help 
uiulerscore then |iro- 



( ( iiil j'lh'id ('I iIk II( iiIiIi AIIciiis vainpits wiiihdii.i \ ilu 
iiiiui UiHi Id the Mule's I ili:(n\. 



( iiiiliiiiitJ (III /'i;i.'i /" 



Faculty Profile 



Relishing tlie challenge 



L; 



By Melissa Matson 

Diaz likes a challenge. 
Il\ a characteristic that has 
shaped his medical career 
ind ser\es him well as the 
new chair ol the Department of Der- 
matology. 

Born and educated in Peru, Diaz 
had no idea that he'd spend the 
greater part of his adult life in the 
United States. Nor did he have any 
idea that after 10 years as chair of 
dermatolog\ at the Medical College 
of Wisconsin, he'd lea\e his position 
and the state he called home to mo\ e 
to North Carolina. 

Life in Peru 



Diaz considers himself fortunate ^^^ 
to have attended medical school in 
Peru in the late 196()s. "The medical 
school was new, though it was p;ul of 
one of the country's oldest uni\ersi- 
ties founded by Liberator Simon de 
Bolivar in 1824," said Diaz. "It was 
affiliated with a brand-new teaching 
hospital w hich meant we had the lat- 
est technolog\ and teaching." '-'"'> ^"'-"- ^^I^ 

Follow ing his last year in medical 
school. Diaz accepted a residenc\' position in 
inlenial medicine. During that \ear, he decid- 
ed that he w anted to become a specialist. "In- 
ternal medicine was too general for me," 
said Diaz. "I needed a field I could go more 
in-depth in." 




Coming to the U.S. 

He had planned to finish his training and 
practice medicine in Peru. But a challenge 
from some classmates made him consider 
other options. 

"It ne\ er crossed my mind to come to the 
United States," said Diaz. "But w hen I found 
out that two classmates v\ere taking a United 
States licensing exam, I had to take it tt)o." 

Diaz passed the exam in \^M. and shortly 



thereafter, the job offers began rolling in. 
"My timing was good," Diaz said. "Man\ 
U.S. hospitals at that time were suffering 
from a shortage of physicians." 

But before Diaz could accept an offer, he 
had to resohe an issue in his personal life: his 
relationship with Dora, his long-time girl- 
friend. "I asked her to maiTX me in October 
1969," said Diaz. "We got married that De- 
cember, and two weeks later, we mo\ ed to 
the United States." 

Furthering his education 

Diaz started his training in the United 
States as a medicine intern at New York's 
Ellis Hospital. He found himself well pre- 
pared for w hat he'd tace that first year. 

""Mn clinical training in Peru exposed me 



to so many patients, so I was wav 
ahead of my peers clinically." said 
Diaz. "The challenge for me was 
the language banier." 

During his time at Ellis Hospi- 
tal, Diaz considered more careful- 
ly the areas of medicine in w hich 
he might specialize. He 
knew he enjoyed dermatology, 
and he was intrigued by im- 
munology. So he applied 
to residencies that offered the 
chance to study both. 

At the Department of Derma- 
tology at SUNV-Buftalo, Diaz 
found exactly what he was look- 
ing for — a nourishing communi- 
ty of immunologists and the 
beginnings of a tleld called im- 
munodermatology. Among his 
mentors were nationally recog- 
nized dermatologists Dick Dob- 
son, MD, his department chair, 
and Thomas T Pro\ost, MD. w ho 
later became chair i)f dermatol- 
ogy at Johns Hopkins School of 
Medicine. 

Following his residency, he ac- 
cepted a fellowship at Mayo 
Graduate School of Medicine in 
Rochester, Minn. It was during 
his fellowship that he began re- 
search into two autoimmune diseases of the 
skin, pemphigus vulgaris and pemphigus fo- 
liaceus. research he continues to this da\. 

"Pemphigus \ ulgaris and pemphigus Ibli- 
aceus are rare but serious autoimmune blis- 
tering disorders of the mouth and skin." said 
Diaz. "Before 1950. people would die with 
no treatment. Toda>'. we can treat people w ith 
steroids and immunosuppressive agents. Un- 
fortunately, we don't know the cause of 
human autoimmune disease." 

Beginning an academic career 

Once Diaz finished his training, he had a 
decision to make. 

".■\t that point. I was the father of two chil- 
dren and had offers to go into private prac- 



tice." said Diaz. ""But I was atlraclcd b\ the 
variety in academic medicine, ihe challenge 
of doing research, patient care and teaching." 

So in 1976. he joined the L'ni\ersity of 
Michigan as an assistant professor of demia- 
tology. His chair ga\e him a lah for his re- 
search and start-up funding, then sent him 
out on his own. "I saw patients a few days per 
week to generate a salary and w rote grant 
proposals to gel funding for m\ research."" 
said Dia/. "I had to pro\ e myself."" 

During his years at Michigan. Dia/ had the 
chance to expand his research outside of the 
United Slates. He knew that an endemic tomi 
of pemphigus existed in Bra/il. He also kneu 
several people at the Uni\ersit\ of Sao Paulo. 
and subsequentl) was in\ited to join them as 
a \ isiting professor 

"Brazil was the perfect place to conduct 
research."" Diaz said. "In certain regions, doc- 
tors see several hundred patients per year 
w ith a disease related to pemphigus. I \\ as 
drawn by the opportunits to find out the 
cause of the disease in Brazil, with the goal of 
appK ing that know ledge to find the cause of 
the same disease here in the L'.S."" 

In 1982. Diaz and his junior fellows left 
Michigan for Johns Hopkins. There he se- 
cured his second National Institutes of 
Health grant and further expanded his re- 
search in Brazil. ""It was exciting to work on 
the frontier of research in the U.S. one da\. 
and be in the remotest regions of Brazil the 
next."" said Diaz. 

.All told. Diaz spent six \ears at Johns 
Hopkins. While there he was made the 
schcHtls fourth full professor of dcmiatolog). 

His first chairmanship 

In I9XN. the .Medical College of W'lsccn- 
sin made Diaz an otter he coukln"t refuse — 
a chance to establish the college's llrst tle- 
pariment of dermatology. 

"When 1 got there." said Diaz, "the) onl\ 
had six residents and a part-time laculls 
member. So I was starting from scratch " 

That was a challenge he relished. He stall- 
ed by hiring faculty for a laboratory and then 



hired clinical people. Ten sears later. Diaz 
said. Wisconsin had one of the best dermatol- 
og_\ programs in the midw est. 

His claim is not without suppiirt. In IWS, 
Wisconsin"s demiatolog\ department ranked 
14th in the nation in NIH funding. In the 
same year, UNC w as ranked 1 1 th. 

His department's residency program also 
won a prestigious aw ard from the American 
Academy of Dermatology that recognized 
excellence in innovati\e teaching. The resi- 
denc\ program included a two-month rota- 
lion at the Uni\ersity of Sao Paulo. Brazil. 
Department of Dermatolog\. (Note: This 
exchange program has been transferred to 
UNC and made a\ ailable to residents here. ) 

Coming to Chapel Hill 

In earl> 1999. Diaz recei\cd letters Irom 
se\ eral search committees — one from the 
University of North Carolina. They wanted 
to inters iew him for their dennatology chair- 
manships. 

"1 woke up to a new reality then."" Dia/ 
said. "First-grade institutions were interested 
in me. That created a restlessness in me as 1 
thought about the possibilities."" 

True to form. Diaz recognized that new 
challenges were w ithin his reach. He decided 
to go through the inler\ iew process. In the 
end. he chos'e L'NC. 

"UNC was quick w ith its offer. '" said Diaz. 
"".And 1 saw here the chance to establish a 
strong research collaboration between our 
faculty and those in the departments of im- 
munology and epidemiology. That was \er\ 
impoiianl in ni\ own research." 

His vision 

Diaz joins UNC"s dermatolog\ depart 
ment at what he sees as a pivotal lime. ' The 
department has a wonderful national ie|iLita- 
tion."" said Diaz. "But the departmenl is going 
through a transition as one generation of 
leadership is taking a step back. I w ant to es- 
tablish lounilalions that will help Ihe depart- 
menl atlvancc bevdiul w here il has been " 





Luis A. Diaz, MD 


Born: 


September 16. 1942, in 




Cascas, La Libertad, Peru 


Wife: 


Dora 


Children: 


Luis. Jr., MD. 29: 




Fernando, 24: and Carlos, 22 


Personal 


Computers, cooking. 


interests: 


mo\ ies and fishing 


Became 




U.S. citizen 


: 1982 



Those foundations include making the de- 
partment attracti\e to a new generation of 
demiatologisis who might otherw ise choose 
private practice. They also include making 
sure his department is prepared for the in- 
e\ ilabililN of increased ci>mpetition. 

■"You know, up until now. we dermalologi- 
cal clinical practices al man\ medical 
schools ha\en'l reall\ had to wori_\ aboui 
w here the mone\ will come from."" said Dia/. 
"But now many are experiencing the stress of 
competition w ith managed care. I wani to 
make sure we"re ready for il here."" 

If there"s one thing that this current presi- 
dent of the SocieU for In\esligati\e Derma- 
tology w anis to make sure others know about 
him. it"s that he"s a team player "Fxe been in 
academia lor most i>f in\ career and ha\ e 
seen many different management si\les. in- 
cluding divisi\e t)nes."' said Dia/. "1 look for- 
ward to working w ith this administialion ami 
my colleagues to further the work begun 
here. .And 1 will do m\ hesi lo lullill ihc mis- 
sion of this departmenl in palicnl care, med- 
ical education, research ,ind comimmil\ 
ser\ ice."" D 



Teacher-Student kidne 
UNC Hospitals and gain; 



By Karen Stinneford 

An otherwise routine ii\ ing-donor 
kidney transplant at UNC Hospi- 
tals captured the national media 
spotlight last April when Jane 
Smith, a middle-school science teacher trom 
Fayette\ ille. gave a kidney to one of her stu- 
dents, Michael Carter 

The human-interest appeal of the 
"teacher-student kidney transplant" story at- 
tracted reporters from media outlets such as 
People magazine. The New York Times. NBC 
Nightly News and Dateline NBC. 

Michael had been bom with renal dyspla- 
sia, and a result, one of his kidneys failed to 
grow and function \\ hile the other functioned 
only minimally. He began undergoing dialy- 
sis treatment in June 1998. and his name was 
added to LlNC's kidne\ transplant waiting 
list in March 1999. 

The poignant story unfolded when .Smith 
watched Michael, now 15. toss a football 
with some other students on the playground 
at Max Abbott Middle School last year. 

Smith knew nothing about MichaeTs 
medical condition while she watched him 
throw and catch the ball. To her. it seemed he 
was "a step or two behind the other kids each 
time." which she attributed to the baggy 
pants and shiil he w as wearing. 

During a break in pla\. Smith told Michael 
that if he wore tighter-fitting clothes, he 
could keep up with the other students. He 
replied that he wore loose clothes because he 
was undergoing dialysis three times weekl\ 
and the loose clothing made the procedure 
more comfortable. 

As Smith would later describe it at a new s 
conference, the con\ersation w ent like this: 

"You're not on dialysis." Smith said in dis- 
belief. 

"T am. too." Michael said. "1 need a 
kidney." 

"Well. 1 ha\e two — do you v\ant one of 
mine?" Smith replied. 

Although Smith's offer to donate a kidne\ 
was a spontaneous gesture, it was a sincere 
one. She ga\ e Michael a slip of paper with 

6 



her name and home phone number on it. and 
told him to give it to his mother. Deborah 
Evans. Carter did. and when his mother 
didn't call immediately, he pestered her. 

At the news conference. Evans recalled 
that she was hesitant to contact Smith be- 
cause she didn't want her son to get his hopes 
up. About a dozen of Michael's relatives had 
been tested as potential donors and no one 
matched. The likelihood that a teacher from 
the school playground would match seemed 
slim. E\ans said. 

Yet Michael persisted. Every time he 
passed his mother in the hall at home, he 
asked whether she had called Smith yet. 

"She's the one. Mom — I just know it." 
Michael told his mother repeatedly. 

So E\ans made the phone call, and soon 
Smith was at UNC Hospitals undergoing 
tests to detennine whether she was a suitable 
match for Michael. She was. 

The transplant w as scheduled to take place 
in December, but was postponed when 
Michael de\eloped an infection just prior to 
surgery. In April. Smith and Michael were 
admitted to UNC Hospitals and this time, 
they felt, the surgerv w as meant to take place. 

Mark W. Johnson. MD. director of the 
renal transplant program at UNC. removed 
Smith's kidney laparoscopically on Friday. 
April 14. before handing it off to David A. 
Gerber. MD. assistant professor of surgery, 
for transplantation into Michael. 

Other members of Smith and Michael's 
medical team included: Elizabeth Friedman. 
RN. transplant nurse coordinator post-op; 
Debbie Sue Gipson. MD. pediatric nephrolo- 
gist: Becky Knotts. CCSW. clinical social 
w orker; Lynn McCoy, RN. CNN. renal trans- 
plant nurse coordinator: Ann Morris, RN, 
nurse practitioner; and Beverly Rodegast, 
RN. transplant nurse coordinator post-op. 

By the morning of Monday. April I 7. 
Smith had recovered sufficiently enough to 
appear with Michael's mother and Gerber in 
live inter\iew s on The Today .Show. Good 
Morning .America and MSNBC. They also 
conducted interviews with NBC 
Nighilx News, which sent a film crew to 
UNC Hospitals. 



Later that afternoon, they held a nev\ s con- 
ference for TV. radio and print reporters from 
throughout North Carolina. Subsequent 
news stories appeared in USA Today. The 
Wall Street Journal 's Southeast Edition, the 
Atlanta Journal-Constitution, the Boston 
Globe, the Chicago Tribune and Houston 
Chronicle, and aired on TV stations in 
Cincinnati, Cleveland, Dallas, Detroit. 
Kansas City, Los Angeles, New York. 
Philadelphia, Phoenix, Salt Lake City and 
San Francisco. 

Smith left UNC Hospitals follow ing the 
news conference, just 72 hours after her kid- 
ney was removed. She returned to her class- 
room about two w eeks later. 

"I feel fantastic." Smith recently stated. "If 
it weren't for the reminder (scar) on my ab.- 
domen. I really wouldn't know I'd done it. It 
only took three weeks to feel I had full ener- 
gy again." 

Michael's mother also reported that he is 
feeling belter than he has in years. 

"Michael is doing great." Evans said, 
adding that doctors have given Michael per- 
mission to start playing his beloved basket- 
ball again. 

Both families gave high praise to the 
health-care providers and staff at UNC Hos- 
pitals. 

"Regarding m\ thoughts about the doc- 
tors, nurses, transplant coordinator, public- 
relations department, food service and 
transportation at UNC Hospitals — well, let 
me just sa\' I am proud to be a UNC alum- 
nus," Smith said. "The skill, care, instruction, 
counseling and support v\ere amazing. Drs. 
Johnson and Gerber are phenomenal men. 
Their know ledge and concern for the patient 
gi\e confidence and comfort, and I w as ne\ er 
anxious for one moment. They are a credit to 
their profession. 

"I just can't say enough about m_\ 
enormously positive experience at 
UNC Hospitals." 

E\ans agreed. "I've been to other hospitals 
with Michael and felt I had to w atch him con- 
stantly." she said. "But at UNC. I knew 
I could lea\e his room and go to the cafeteria 
and be comfortable v\'ith that situation. 



ransplant takes place at 
lational media attention 




Jane Small and Mliluwl Carter spend same lime reading: i;cl well wishes an a pra\ir c lunn liiniiiini; in MuluuTs hospital , 



W'c fell so secure. I knew Michael was in 
;ju( id hands" 

Since her surgen. Smith has been honored 
at. and in\ ited to speak at. conferences recoy- 
ni/in<; the \aluable contributions of vohin- 
teers or promoting awareness about organ 
donation. She is pleased with how the news 
media has portra\ed the transplant. 

"The media interest was unbelie\ahle — 
and persistent, as I am still getting calls." she 
said. "The coverage has been, vv iihoul excep- 
tion, tremendous!) supporti\e of the process. 
ms profession as a teacher and m\ faith. I re- 
ally can't complain uhen the press is so posi- 
tive about issues 1 care sodeepl\ about." 



.■\nd if her and Michael's story persuades 
one person to consider becoming an organ 
donor, she said, the media attentitni will be 
well worth it. 

According to the Carolina Donor Ser\ ices 
in Durham, about 67.()()() Americans current- 
ly are av\ ailing a life-sas ing organ transplant. 
Thirteen people on the national wailing list 
die e\ery day. and some 4.S.'i,S people died in 
1998 when organs did not become a\ailable. 
A new patient is added \o the national organ 
waiting liste\ery 16 minutes. 

In North Carolina. nearU 2..^(HI people are 
awaiting an organ transplant. l'eo|ile ages IS 
and older can indicate their tlesire to donate 



by signing a donor card and expressing their 
wishes to family members. kelati\es can do- 
nate a deceased family member's organs and 
tissues regardless of that person's age. 
.As many as 50 people can benefit from 
one person's decision to donate. For more 
information about beci>ming an organ donor, 
people can call The Coalition on Donation 
at (SOO) .V^.'i-SHARI: or \isit the 
organi/ation's World Wide Web site 
www. shares ourlife.oii; [J 



Top mouse geneticist he 



By Leslie H. Lanj; 

The intcriiiilionally renowned 
mouse genetieist. Terry R. 
Masinuson. MD. reeently joined 
the UNC Sehool of Medicine to 
head a new genetics department and ge- 
nomics initiative. 

Magnuson. one of the most sought-after 
scientists in mammalian genetics brought 
with him his entire 13-member laboratory 
group from Case Western Reserse 
University. 

In his tenured appointment as Sarah 
Graham Kenan professor and chairman of 
genetics, Magnuson became founding head 
of the medical school's newest department. 
The program will be housed in a KM). ()()()- 
square-foot human biology research build- 
ing currently under construction w ith a 
combination of public and private funds. 

TeiTy chose UNC over many other op- 
pi)rtunities, some of which offered substan- 
tially larger resources than we currently 
ha\e." said Jeffrey Houpt. MD. dean of the 
.School of Medicine. "He was intluenced by 
the exceptional science programs here, the 
careful planning of our needs and strategies 
and the collegial atmosphere of the entire 
research community." 

During visits to Chapel Hill. Magnuson 
took particular note of the reality behind 
Carolina's reputation for interdisciplinary 
research. 

"It's a very collegial place, and that's 
w hat struck me when I came through. \er- 
sus other institutions I visited." he said. "If 
one wants to put together a uni\ersity-w ide 
center, it seems nn>re likely to happen at 
UNC because of the culture. .-Xnd I find that 
very exciting." 

Funding also was an important factor in 
Magnuson's decision to come to Chapel 
Hill. The School of Medicine \\i\\ recei\e 



$2.6 million over 
four years from the 
Howard Hughes 
Medical Institute to 
help develop and 
staff its new genet- 
ics center. 

"The genetics 
center will comple- 
ment existing re- 
search strengths at 
UNC in the study of 
mouse models of 
diseases, genetics of 
model organisms, 
cancer research and 
clinical genetics." 
said William F. 
Mar/luff. MD. ex- 
ecutive associate 
dean for research at 
the School of Medi- 
cine. "The nmney 
will establish the 
genomic core tech- 
nologies we need on 
campus and a chro- 
mosome imaging 
facility for detecting 
alterations in cancer 
as well asabnonnal- 
ities in genetic dis- 
eases." 

Of 1 05 U.S. med- 
ical schotils competing for the Hughes 
grants. UNC was among 41 winners. 
Awards ranged from $1 .6 million to S4 mil- 
lion. 

According to Hughes olTicials. the suc- 
cessful proposals emphasized collabora- 
tions between researchers in basic sciences, 
clinical research and bioinfonnatics. a field 
that mairies computer science with molecu- 
lar bioloev to anah /e the massise data 




Tcny R. Magnuson, MD 



being generated by the Ll.S. Human 
Genome Project. The project by the U.S. 
Department of Energy and the National In- 
stitutes of Health will identify more than 
lOO.OOO genes in human DNA. determine 
the sequences of the three-billion chemical 
base pairs that make up human DNA and 
store this infonnation in databases. 

"We're going to build a major genomics 
program here at UNC." Marzluff said. "Ten 



ids new UNC program 



new School of MediLine facLiltx uill be 
added in this area. \\ iih a locus on the genet- 
ics of complex diseases. In addition, the 
School of .Medicine and the College of .Arts 
and Sciences w ill recmit at least fi\e neu fac- 
ult> in bioinfomiatics." 

,A portion of the Hughes grant will be used 
to recruit four junior facultN working in 
mammalian genetics by offering start-up 
packages for equipping their laboratories and 
pro\ iding support for technical personnel 
and supplies. 

Magnuson already has signed on se\eral 
of the nation's lop assistant professors to 
UNC. They include David Threadgill from 
Vanderbilt University, Fernando de Villena 
of Temple University and the Fels Institute 
for Cancer Research, and Stanford's Charles 
Perou. a young leader in cancer genetics and 
micro-array analysis of multiple genes. 
Perou's recruitment was done jointly with 
the UNC Lineberger Coniprehensiv e Cancer 
Center. 

"In looking at genetics and genomics at 
UNC-Chapel Hill. I see an incredibly strong 
medical genetics effort spread across obstet- 
rics and gynecology, pediatrics anil medi- 
cine." .Magnuson said. "The cy stic fibrosis 
center is entering into a national consortium 
to look for modifiers of CF. Molecular diag- 
nostics is important within the clinical de- 
partments, and the Lineberger 
Comprehensive Cancer Center has begun an 
important research program in this area, as 
well. There's genetic epidemiology, biosta- 
tisiical genetics and nutrition in the School of 
Public Health, all of which are important to 
the success ol a genomics program." 

According to Magnuscm. the ongoing 
public and commercial genome projects are 
generating an unprecedented amount of in- 
lormation leading to a comprehensive dia- 
log of all known human genes. 

"And Irom this we're seeiiiL: cmeruiiiL' 



technologies, new data on gene sequencing 
and this is leading to greater e\pK>ration of 
gene functiim." he said. "More than learning 
the function of individual genes, what is real- 
ly important here is looking at the function of 
genes collectively, as interacting networks of 
genes within the entire genome — this 
means complex genetics and complex disor- 
ders. And that's vv here the genome project is 
allow ing us to go." 

Given the inevitable explosion of genetic 
and genomic information at the molecular, 
organismal and population levels, the entire 
biomedical research enterprise is undergoing 
a paradigm shift away from hypothesis-dri- 
ven research. Magnuson said. 

"Now. having these vast amounts of cata- 
logued infomiation. we have discovery-dri- 
ven research; that is. we're analyzing this 
information." he explained. "And this will 
lead back to better hypothesis-driven re- 
seiirch. After analyzing gene sequences, you 
can predict functional relationships based on 
sequence and then test these functional rela- 
tionships. This is leading to incredible iiifor- 
matii>n on genetic v ariances associated vv ith 
disease predisposition and the prediction of 
therapeutic responses to drugs. |the field ol'l 
phamiacogeneties." 

In Magnuson's v ision. a genomics center 
contains key components in adi.litioi) to the 
science. 

"We must deal not only with the science 
and scientific discoveries but vv ith health- 
care issues, the business enterprise, including 
technology development and transfer, 
bioelhics. and the legal and social impacts 
of genomics iliscoverics on public policv." 
he said. 

"1 env ision biomedical engineering as an- 
other key component to bring us fuilher into 
imaging technology, microfabi icalion of 
sensors, molecular diagnostics, ami arr.iv 
lechnolo'jv." he adtled. ".And iheii ihcre arc 



the educalional and training programs at all 
levels — undergraduate, graduate, medical, 
social, business. 1 think a genomics center 
at UNC must encompass all these ditfeient 
components." 

Why the genetics initiative at Chapel Hill 
now .' Houpt summed it up succinctly. 

"L'nless you have an excellent program in 
genetics, you'll be incapable of aspiring to be 
a leading medical school or a leading univer- 
sity in this country." he said. "This is one 
dance vou can't sit out." D 



CommeiTiorative plaque honoring W. Reece 
Berryhill, MD, to be unveiled Oct. 10 

A commemorative plaque honoring the contributions of fomier School of Medicine 
Dean W. Reece Berryhill, MD, will be unveiled Oct. 1 0. 

The plaque presentation will take place as part of the 1 6th annual Norma Berryhill Dis- 
tinguished Lectureship. 

The plaque, contributed by grateful alumni, contains comments made by University 
President Francis P. Venable (1956-1934) during his University Day address in Chapel 
Hill on Oct. 12, 1900. Venable's comments were published in the Charlotte Daily Ob- 
server two days later on Oct. 14, 1900. the same day Berryhill was bom in a Mecklenburg 
County community. 

For both men, visionaries of their times, the sentiments would reflect the principles 
upon which they based their administrations. The te.xt of the plaque is as follows: 

"The University of a State, when it tnily fulfills its duty, should be its chief strength and 
glory, a light for the people, the fountain-head of their higher life, the .source of their up- 
lifting and upbuilding, the bulwark of their liberties. It moulds the leaders of the people. 
Streams of inlluence flow from it to gladden the whole land. . ..Great movements for the 
bettering of the condition of the people. . .spring from it. 

"The founders of this State in their sturdy independence and far-seeing wisdom recog- 
nized the importance of such an institution, and so, while the struggle for freedom was 
still upon them, provided for the establishment of this University — the chief safeguard 
of their children against the loss of those liberties for which they fought. And should 
some one come and offer to endow this institution w ith many millions and remove it from 
the control of the State, it wouldbeasaleof their birth-right of those children, a betrayal 
of the trust of the fathers. The citizens of this State cannot afford to have this University 
narrowed down to the political platfomi of any one party, to the creed of a single sect, to 
the economic belief of any individual philanthropist. Parties, churches, philanthropists, 
all can center their efforts here and unite in the making of a great people, a grand Com- 
monwealth, but the people must control. The truest democracy in this State is found right 
here — a w ise tolerance for all shades of opinion and belief." 

The plaque, which depicts the images of both Berryhill and Venable. will be mounted 
in Berryhill Hall. 



Ciin/iiniiil Iniiii piii^t' .i 

lessional authorit\, McLendon added. 
Berryhill put his stern countenance to good 
use. 

"He was an imposing and intimidating 
person, and it was the most dreaded thing to 
get called to his office." McLendon said. 
"One time a student got called to his office, 
and Dr. Bern hill made him sit there while he 
finished up some task. Finally, Dr. Berrvhill 
said. "Do you like medical school?' and the 
student replied v\ ith great trepidation, "Yes 
sir. 1 do.' He said, 'Well, that's good because 
you're in the top 10 percent of your class. 
Keep up the good work.'" 

When BeiTyhill stepped down as dean in 
1964, he was named Sarah Graham Kenan 
professor of medicine and became director 
of the Division of Education and Research in 
Community Medical Care. During the five 
years he served in that position, he broad- 
ened the Uni\ersity's teaching base by ar- 
ranging hospital affiliations throughout 
North Carolina. Out of these cooperative 



arrangements — which provided full-time 
faculty for the associated hospitals — grew 
the N.C. Area Health Education Centers pro- 
gram. 

Today, some 28 years after it was created, 
AHEC continues to help meet the primary 
health care needs of the state by improving 
the supply, distribution and quality of health 
care professionals. Students who attend 
UNC's medical or phannacy schools are re- 
quired to complete nearly half of their clini- 
cal rotations at AHEC sites. 

For his work laying the foundation for the 
AHEC program, Berrvhill was named a mas- 
ter of the American College of Physicians in 
1977 — the highest level an individual can 
attain within the organization. 

When he wasn't at the School of Medi- 
cine. Berryhill loved working in his yard, 
planting fiowers. trees and shrubs, and tend- 
ing to the family's large vegetable garden. He 
rareh went to his office in the summertime 
w ithout takini: alona some tlowers or \eizeta- 



bles for co-workers, students or patients. 

An a\ id reader and classical music con- 
noisseur. Berryhill lo\ed sports and could 
rattle off baseball .statistics dating back to 
the 1920s. It was an interest fueled when 
Berryhill served as director of the student 
infirmary and his task involved caring for 
the university's athletes. 

For someone uncomfortable v\.ith public 
praise and accolades. Berryhill had to en- 
dure much of both dunng his career He re- 
cei\ed the O. Max Gardner Award and the 
Cio\ernor's Distinguished Citizens Award 
in 1964, and in 1971. former students and 
house officers in his home county. Mecklen- 
burg, honored him by creating the W. Reece 
Berryhill Mecklenburg Medical Scholar- 
ship. 

In 197.^ the School of Medicine honored 
him by naming one of its buildings Berryhill 
Hall. The basic sciences building for health 
affairs students cost slightly more than the 
General Assembly's original 1 947 appropri- 
ation for the hospital and medical school. 

BeiTvhill retired from the faculty in 1 97 1 . 
He died at the age of 78 on Jan. 1 .'|979, the 
year that marked the centennial anniversary 
of medical education at Chapel Hill. He is 
buried at his beloved campus in the Old 
Chapel Hill Cemetery. 

One former colleague summarized 
Berryhill and his career as follows: "Dr. 
Berryhill's inherent Scotch-Irish modesty 
and reticence would never permit him to 
admit his towering contribution to this med- 
ical center... hut so broadly ha\e Dr Berry- 
hill's talents ranged and so inextricably is 
his life interwoven with the fortune of this 
school that one cannot mention one v\ ithout 
thinking of the other." D 



10 



Contributions of Norma 

Berryhill honored in 

distinguished lecture series 



Wi' 



lie her husband. 
\V. Reeee Bernhill. 
MD. was bus\ 
buildine a deeiee- 



conterring medical school and at- 
filialed leaching hospital. Norma 
Connell Bernhill was bus\ build- 
ing a communit). 

Indeed, "her hospitalit\ helped 
con\ ince those young, hot-shot 
medical faculty that this would be 
a good place to teach and do re- 
search and raise their families." 
one colleague said. 

Mrs. Berr\ hill's contributions 
to the School of Medicine and 
UNC Hospitals were so instru- 
mental to their growth that a dis- 
tinguished lecture series was 
named in her honor. The Norma 
Berryhill Distinguished Lecture- 
ship takes place each fall and fea- 
tures an accomplished School of 
Medicine faculty member 

Raised on a farm in Warren 
Count\. the oldest girl among 10 
children. Mrs. Berrshill met her 
future husband in 1921 when she 
was a student at Peace College. 
After transferring to Carolina and 
recei\ing her bachelor's degree in 1925. she 
mo\ed to New York City and studied for a 
master's degree in sociology while working 
in a settlement house for immigrant women. 
She married Bernhill in 19.^0 after returning 
to North Carolina to ser\e as dean of girls at 
Charlotte's Central High .School. 

When Berryhill became dean ot the 
School of Medicine, it had just 4,S tacults 
members and a two-year curriculum that 
forced students to complete their medical ed- 
ucation elsewhere. When Berryhill stepped 
down 2.'^ years later, the School of .Medicine 
had 4.^.^ faculty members, was awarding 
medical degrees and operated a highls re- 
spected academic medical center 

Persuading phssicians to come to Chapel 




r 

Norniii C. 



Bernhill 

Hill in the I94()s and early I95()s was a chal- 
lenge. There was only one hotel in town — 
the Carolina Inn — and few restaurants, so 
the hospitalit) Mrs. BenAhill extended was 
crucial to recruiting new faculty and helping 
them feel welcome and connected after the\ 
arri\ed. She frequently hosted dinners 
and teas for facults members and their w i\ es. 
and it became a common sight to 
see her taking lacults lamilies casseroles 
or desserts. 

"Chapel Hill was just a little southern \il- 
lage — it vKasn't the town it was today." Mrs. 
BerPthill said. 'Making new people feci wel- 
come was just something neighbors did " 

Kenneth Brinkhous. Ml), who fiisi \isited 
the Berrvhill home in I'Mfi. recalled ihc 



BeiTx hills' laiiious li(is|iiialit\. 

"The school was \erN small 
back then and there v\ as a feeling 
o\' w armth and closeness." he 
said. "Mrs. Berryhill lent grace 
and dignity and was alw ays sen- 
siti\e to the needs of faculty and 
students. Her home was always 
open, and that atmosphere of gra- 
ciousness was so important in 
helping recniit the faculty needed 
to expand to a four-\ ear school." 

Mrs. Bern* hill alsi) was instru- 
mental in organizing the L'niver- 
sit}, Woman's Club and creating 
the N.C. Memorial Hospital Aux- 
iliary. Now called the Volunteer 
Association, the organization re- 
cruits \ olunteers w ho donate 
more than .'^2. ()()() hours of their 
time to UNC Hospitals annualK . 
Colleagues sa\ the late dean 
fully appreciated the \alue of his 
w ife's contributions, once re- 
J marking, "she did more than ans - 
j body." 

1 This year's Norma Berr\ hill 

Distinguished Lectureship 
lakes place at 3 p.m. Tucday. 
Oct. 10. in Gerrard Hall and fea- 
tures George Sheldon, MD. Zack D. Owens 
distinguished professor of surgeiy and chair- 
man of the Department of Surger>'. Sheldon 
is the chair-elect of the .Association of Amer- 
ican Medical Colleges. He is one of less than 
20 surgeons in the last 100 sears to ser\c as 
president of all major surgical organizations, 
incUuling the .•\merican College of Sur- 
geons, the American Surgical .Association, 
the American Association tor the Surger\' of 
Trauma and the American Board of Surgery. 
The authoi- of more than .^00 articles and 
book chapters. Sheldon has held editorial 
board appointments at se\eral national peer- 
rev iewed medical journals. □ 



Faculty 

Notes 

Alice S. Ammerman, DrPH. RD, associ- 
ate prcifessiir of 



nutrition, is the 
recipient ot the 
Bernard G. 
Greenberg Alumni 
Endowment 
Award. The 
award is gisen 
a II n u a 1 I y t o 
an outstanding 
lull-time faculty 
member of the 
.School of Public 




Aininernuin 



Health for excellence in the areas of pub- 
lic health research, service and teaching. 
Continuous demonstrated excellence in 
service to the broader public health com- 
munity over a number of years is a major 
criterion of the award. 

Paul F. Dunn, MSN, FNP, CDE. clinical 
assistant professor of family medicine, has 
been elected chair of the "Patterns of 
Care" Taskforce for the NC State Diabetes 
Ad\isory Council — a council appointed 
by the gmernor. The taskforce has repre- 
sentation from diabetes pro\ iders through- 
out North Carolina directed toward help- 
ing primary caregi\ers in their delivery of 
diabetes care. 

David Fensferniacher, PhD. research 
assistant professor of pharmacology, act- 
ing director of the Center for Biolnformat- 
ics and director of scientific computing for 
the School of Medicine, has recenth been 
awarded a $5().()()() grant from the Small- 
wood Foundation. The grant will be used 
to establish both undergraduate and gradu- 
ate student assisiantships in bioinformat- 
ics. and also to de\elop a bioinlormatics 
seminar series. 

Adam O. Cold.stein, MD. assistant pro- 
fessor of family medicine, was recently 
presented with a certificate of apprecia- 
tion, signed by N.C. Gov. James Hunt, in 
recognition of dedication and outstanding 
ser\'ice to North Carolina in his efforts 
working with teen tobacco use. 

Robert E. Gwyther, MD, MBA. piofes 
sor of family medicine, was elected vice 
president of the N.C. Academy of Family 
Physicians. Gwyther recently traveled to 
Moscow. Russia \\\lU a group from the 
National Institute on Alcohol Abuse and 
Alcoholism (NIAAA). where he partici- 
pated in teaching techniques of alcoholism 
inter\eniion to Russian phvsicians. 



Timothy J. Ives, PharmD, MPH. clinical 

associate professor of family medicine, 
has been selected as a fellow by the 2()()() 
L'.S. Public Health Service Primary Care 
Policy Fellowship program. 

Rehecca J. Laudicina, PhD. assistant 
professor of clinical laboratory science, 
has established the Hemochromatosis 
Education and Screening Project with a 
$200,()()() grant from the Kate B. Reynolds 
Charitable Trust. The planned two-year 
project will include an educational pro- 
gram offered through the NC Area Health 
Education Centers, and the screening of 
low-income people in 14 western North 
Carolina counties for this common genetic 
disorder. 

Warren P. Newton, MD, MPH. associ;ite 
professor and William B. Aycock Distin- 
guished Chair of family rnedicine, has 
been appointed to the board of directors of 
the NC Academy of Family Physicians. 

David W. Ollila, MD. assistant professor 
of surgery, has 
accepted the posi- 
tion of director of 
the Multidiscipli- 
nary Sentinel 
Node Proizram at 
UNC. Ollila com- 
- '-■ pleted an NIH- 

^^V funded surgical 

^^^k ^m^^^^^^ oncology fellow- 
^^H ^ ^^^B ship John 

Wayne Cancer 
OMo Institute. Santa 

Monica, Calif., in 1997 and stayed for an 
additional year as the assistant director of 
surgical oncology. At the Ji)hn Wayne 
Cancer Institute. Ollila trained with the 
pioneers of sentinel lymphadenectomy in 
melanoma (Donald L. Morton. MD) and 
breast cancer (Armando E. Giuliano. 
MD). Since arriving at UNC. Ollila has 
helped to complete an institutional breast 
cancer sentinel node validation trial, 
which documents UNC's high accuracy 
rate with the technique. Ollila is a member 
of the American College of Surgeons 
Oncology Group Breast Section, which 
currently has two national sentinel node 
protocols. 

Ollila was also recently selected by 
L'NC medical students for membership in 
Alpha Omega Alpha (AOA), the only 
national student honor medical society in 
the world. The societv "s chapters annually 
offer membership to a faculty member 
who has distinguished themsehes in their 
professional career. 




Catherine N. Otto, PhD, MBA. assistant 
protessor of clinical laboratiiry science, 
has been appointed to the National Com- 
mittee on Clinical Laboratorv Standards" 
Subcommittee on Total Error for Labora- 
tory Methods. 

(Jeorge F. Sheldon, MD. Zack D. Owens 
distinguished professor and chair of 
surgery, has been awarded the Llni\ersity 
ot Kansas Medical Alumni Association's 
2000 Distinguished Alumnus Award in 
recognition of his outstanding contribu- 
tions to society and to the profession of 
medicine. The purpose of this prestigious 
award is to provide a role model and a 
source of motivation for current and luture 
medical students. The award is presented 
to an individual who is a graduate of the 
University of Kansas School of Medicine, 
and who has made niileworthy contribu- 
tions to the theory and practice of medi- 
cine and to the health of all people 
through patient care, research and teach- 
ing skills. Sheldon received his MD from 
the University of Kansas School of Medi- 
cine in 1961. 



Benjamin M.W. Tsui, PhD. professor 
and director of research in biomedical 
engineering, has been appointed vice- 
chair of the department. 



Alumni Association 
Honors Five 



The School of Medicine and the 
Medical Alumni Association pre- 
sented tl\e Distinguished Ser\ ice 
Awards and the Distinguished 
Facult) Award at its annual awards banquet 
heldNia\.r 

This year's Distinguished Service Award 
recipients were: Walter R. Da\ is of Midland. 
Texas: Otis N. Fisher. MD. of Greensboro: 
James D. Hundle>. MD. of Wilmington; and 
William L. London. MD. of Durham. The 
Distinguished Faculty Award went to Harold 
Roberts. MD. of Chapel Hill. 

• .A nati\ e of Pasquotank County. Davis is 
"^wp-*-=<C perhaps best 
know n for his role 
^ in spearheading 
1 the creation of the 
university's S23- 
niillion central 
Academic .Affairs 
librarv that bears 
his name. T h e 
Texas business- 
man not onlv 
w orked to per- 
suade the .N.C. 
General .Assembly to fund the library w ith 
the sale of university-owned utilities, he also 
personally supplied the lO-acre facility with 
books. Other university beneficiaries of 
Dav is' generosity include the Educational 
Foundation. UNC Press, the School of Social 
Work and last year's Hurricane Floyd relief 
efforts. Davis has served I I years on the 
I'NC Board of Governors and 15 years on 
the I NC-CH Board of Trustees. 

In the medical school, the department of 
ophthalmology has made dramatic improve- 
ments in doctors' ability to track and treat di- 
abetic eye disease, thanks lo considerable 
funding from Dav is. His grants have sent fac- 
ulty members overseas through the Doctors 
Without Borders and Phvsicians for Peace 
programs, Davis also put in countless hours 




Davis 




explaining to state legislators the fundamen- 
tal need for the UNC Health Care, which 
greatly enhanced the School of Medicine and 
U.NC Hospitals' business tlexibility and al- 
lowed it to compete more fairly in today s 
rapidiv changing health-care miu-ketplace. 

• Fisher is known throughout the stale as an 
expert radiologist w ho steadfastly advocated 
for updated and 
expanded radiolo- 
'^v g> facilities at 
v'.hat is now 
Moses Cone 
Health System in 
Greensboro. Fish- 
er — w ho earned 
his bachelor's and 
medical degrees 
at Carolina — has 
demonstrated his 
Fi\lier lov alty to his alma 

mater time and time again through Schot)l of 
Medicine fund-raising efforts and willing- 
ness to work w ith Area Health Education 
Center students. 

Fisher has served in various capacities at 
local and state levels as a member of the 
boards of directors for the N.C. Chapter of 
the American College of Radiology, the 
Medical Board of the Mo.ses Cone Hospital, 
the N.C. Medical Peer Review Foundation 
and the Southeastern Angiography Society 
— serving also as past president in the latter 
two organizations. He is a member of the 
Guilford County Medical Society and has 
served as president and board member for 
ihc Greensboro Academy of Medicine, as 
well as serv ing on the boards of the Greens- 
boro Heart Association and ihe Crippled 
Children's Societv of Greensboro 

• Huiidlev twice has been included in •■The 
Best Doctors in America: Soulheasi Re- 
gion" Having completed his iindcigiaduatc 
and medical cdiicalioii. research rcllowshi|i 



( ^ 



and residency at 
Carolina. Hund- 
lev has been an 
active member of 
the meilical 

schtiol's .Alumni 
.Association. .As- 
sociation presi- 
dent in 1998-44. 
Alumni Council 
member since 
1990 and Nation- 
al Loyalty Fund HiiiulUy 
Committee member since 1994. he also 
served on the search committee that selected 
the department of orthopedics' first chair- 
man and worked diligentlv to establish the 
chair's distinguished professorship. 

Hundley has been staff physician for the 
Rotarv' Orthopaedic/Regional Crippled Chil- 
dren's Clinic for nearly three decades, the 
past nine years as medical director. For more 
than 20 yeiu-s, he also sened as athletic team 
physician for UNC- Wilmington and was 
given the athletic department's William J. 
Brooks Distinguished Serv ice .Award. In 
1998. he was recognized with the establish- 
ment of the James D. Hundley Outstanding 
Student Trainer Aw ard. A past president of 
the North Carolina Orthopaedic Association, 
he serves on the Governor's Osteoporosis 
Prevention Task Force and the National 
Board for Certification of Orthopaedic 
Phv sicians .Assisianls. 

• .A petliatrician and pctiialric hemalologisi 
for nearly 40 years. London is a 145 1 j'hi 
Beta Kappa graduate of UNC. After allciul 
ing medic.il school at UNC and completing 
naming ai Children's Medical Center in 
Boston. London returned to practice in ihe 
Durham office established bv his uik Ic. 
Throughout his practice. London has served 
as ;i role model faculty member for meilical 
sUklenis. residents and staff at L'NC Hospi- 
tals. Ihe SchiH)l of Medicine. Duke Universitv 



I.^ 



Medical Center, Durham Regional Hospital 
and the lumier Watts Hospital. 

An active member of the American Board 
of Pediatrics since 1979. London served on 
the board of directors for six years and was 
secretary-treasurer for another year. He has 
ser\ed as the long-time president of the N.C. 
Pediatric Society, 
and held numer- 
ous leadership po- 
sitions in the state 
chapter of the 
American Acade- 
my of Pediatrics. 
London was chap- 
ter chaimian from 
1969 to 1974. and 
under his guid- 
ance, the two state 
London organizations — 

once fragmented in their efforts — worked 
collaboratively to champion programs for 
children. 




For 



■ 40 Years follow ine his davs as an 



undergraduate, 
medical student, 
senior resident and 
fellow at Carolina. 
Roberts has ser\ ed 
on the school of 
medical faculty as 
an internationally 
recognized special- 
ist in hematology 
;ind coagulation. His 
curriculum vitae 
includes member- 
ships on committees and councils at the Na- 
tional Institutes of Health, the National 
Heart. Lung and Bhxid Institute and the Na- 
tional Hemophilia Foundation. At Carolina, 
he served as chief of the Division of Hema- 
tology, director of the Center for Thrombosis 
and Hemostasis. director of the Clinical Co- 
agulation Laboratory and director of the 
Comprehensive Hemophilia Diagnostic and 
Treatment Center, the latter of which now 
bears his name. 

In recocnition of his work in the field of 




coagulation. Roberts was granted the Distin- 
guished Career Award for Contributions to 
Hemostasis by the International Society on 
Thrombosis and Hemostasis. where he 
serv ed for 1 2 years as executive director. He 
also was aw arded the society's highest honor, 
the Robert P. Grant Medal, for his research 
mlo the genetic basis of hemophilia. His tal- 
ent as a teacher has been recognized by stu- 
dents who awarded him the Medical Basic 
Sciences Teaching Aw ard. 

The Distinguished Service Award was es- 
tablished in 1 955 to honor alumni and friends 
whose careers and unselfish contributions to 
society have added luster and prestige to the 
LIniv ersity and its School of Medicine. The 
Distinguished Faculty Award, first given in 
1978. recognizes a full-time UNC faculty 
member for excellence in teaching, contribu- 
tions to medicine in the state, leadership in 
continuing education of practicing physi- 
cians and accomplishments in improving 
communications between faculty, alumni 
and people of the state. 



.4 Snapshot of 



Spring Medical Alumni Weekend 



May 5-6,2000 




Walter Davis, seated, shares a moment with Dean Jeffrey 
L Hoiipt. MD. 



Classmates, friends and faculty reminisce at the DSA Banquet at the 
Carcliihi Cliih. 




Sharitii; memories during a look hack. 



The Class of '55 presents its lari^est-ever Loyalty Fund ijift of $150,000. 



14 



Fall Medical Alumni Weekend 

October 20-21, 2000 

UNC Fall Medical Aliunni Weekend Schedule 



FRIDAY 
OCTOBER 20, 2000 



SATIRDAY. 
OCTOBER 21. 2000 



•^^Ml a.m. - 2:30 p.m. CME: Pre\enti\e Medicine: Screening and 
Earl\ Management of Major Medical Dis- 
eases Tlw GiOixi' Watts Hill Alumni Center. 
Chapel Hill 

Registration and Continental Breakfast 
Welcome and Introductions. James R. Harper. 
.MD. Associate Dean for Medical Alumni 
Affairs 

The Re\olution in Diabetes and its Manage- 
ment: Implicatii)ns fe)r Screening. John B. 
Buse. MD. Director Diabetes Care Center and 
.Associate Professor of Medicine. Di\ ision of 
Endocrinolouv 
Break 

11:3(1 a.m. -12:30p.m. Prostatic Malignancy: Decision Marking 
Based on PSA Values. James L. Mohler. MD. 
.Asscxriate Professor of Surger> and Pathology 
& Laboratory Medicine. Member oi UNC 
Lineberger Comprehensi\ e Cancer Center & 
Director. Urologic Oncology 
Lunch 

Screening and Treatment of GI Malignancies. 
Da\id F. Ransohoff. MD. Professor of Medi- 
cine. Di\ ision of Dieesti\e Diseases 



9:30- 10 a.m. 
10 -10:05 a.m. 



10:05- 11:15 a.m. 



11:15- 11:30a.m. 



12:30- 1:30 p.m. 
1:30 -2:30 p.m. 



3 -4 p.m. 



6:30-7:15 p.m. 
7: 15 -9 p.m. 



Special Presentation: "Walter Reece 
Berrvhill. MD. and the Expanded Medical 
School at Chapel Hill." William W. McLen- 
don. MD "56 Ge(>n;e Walts Hill Alumni Cen- 
ter. Chapel Hill 

Six'ial and Banquet. George Watts Hill Alum- 
ni Center. Recognition of new Loyalty Fund 
Associates, student scholarship recipients and 
Endou ment Fund urant recipients. 
S^M:id\-AlumniHalll.ll.lll 
Dinncr-AlumniHalll.ll.Ili 



(The schedule below is based on a "best guess" game kickoff time of 
12:30 p.m. Kickoff is subject to change until 10 da\s prior to the 
date. Call '^)lM-%2-SS4| the week pnor to the game to confimi kick- 
off and morning e\ent schedule. Those u ho pre-registcr b\ the dead- 
line will be contacted w ith an\ appropnate intomialion. ) 



8:30 a.m.- 12 p.m. 



9 a.m. 



9 a.m. 



11 a.m.- 12:15 p.m. 



*^ 12:30 p.m. 



Reiiistration and Ticket Pick Up. 

I siVloor Bern, hill Hall. UNC Campus 

Council Meetmg. 103 Benyhill Hall 

Reunion Campaiiin Stcerini: Committees 
Meeting. 103 BerrNhill Hall 
Classes of "46. ".51. "56. "61. '66. "71. "76. "SI. 
"86. "^)1 

Pig Picking, outside Berryhill Hall in the Stu- 
dent Commons Area 

UNC \ s. Clemson. Kenan Stadium 

*4 TICKETS MAXIMUM. FIRST COME. 
FIRST SERVE. Additional tickets may be- 
come available closer to the game date. Contact 
the Medical .Alumni Office at 9 1 4-462-884 1 . 



ACCOMMODATIONS: Alumni are respon- 
sible f(^r making hotel arrangements. Blocks of 
rooms ha\e been reserved at: 1 ) The Sheraton 
Chapel Hill/ (formerlv the Omm) - 414-468- 
4900 (4/22/00 cutoff). SI 44-^. ID = UNC 
Medical Alumni. 2) LaQuinta Inn & Suites 
(1.8 mi north of 140/15-501 e.xit) - 
4 1 4-40 1 -4660 ( 4/20/00 cutoff. Group #45 1 65 ). 
,$72-1-. $44-)-. ID = l'NC Medical Alumni. A list 
of additii>nal hotels in the Research Triangle 
can be provided upon request. 



(Print and Fax la the .Medical Alumni Oifice) 

FAIL MKDICAL ALIMNI WEEKEND 
REGISTR.\TION 

Deadline: Oelcher .<. 2(10(1 



Name 



Class Year 



Address 



Telephone 



Namc(s) of Guest(s) 



*Social Security (CME only - optional) 



Friday. October 20th: 

CMliWoiiram 
Berryhill Presentation 
Social & Banquet 



# C"' S65.(K) = % 

# (no charge) 

# (p S45,(K) = •«, 

(prc-regislralion required) 



Saturday, October 2Ist: 

Council Vlcclini; # 
Pig Picking: " Adult # 

(i- 1 (i yo # 


C"' $l().(X) = .'j. 
(S' $ 7.(X) = $ 


Foolball Tickcls # 

(MaMiiuiin (it 4 can be ordered! 

Tolal: 


@ $26.(X) = $ 

S 



Method of Payment: 

Check (payable lo Medical Foundation of NO 

Credit Card: VISA Mastcrt^ard 

Signature 

Card # 

Fxpiration: 

KLliini I.. Medical Alumni Ott"icc. UNC-CH 

C.B. # 7(MH). 126 MacNider Buildini: 
Chapel Hill. NC :7.'^94-7(H)<) 

Telephone: (414) 4()2 SS41 or l-S(M)-S62-6264 (ask lo 
be connected). Facsimile (419) 466-1076 
Email: Medical Alumni («' med.unc.edu 



News 
Briefs 



UNC Hospitals ranked 
among best medical centers 
in the nation 

Elc\ en niedic;il specialties ottered at L'NC 
Hospitals rank anioiiy the lop 50 programs of 
their kind nationwide, according to the Jul) 
1 7 issue of U.S. News ami World Report. 

"U.S. New.s has recognized what we al- 
ready knew — that some of the best medical 
experts and programs in the country are lo- 
cated right here at UNC Hospitals," said Eric 
Munson. president and chief executive offi- 
cer. "That UNC Hospitals is consistently 
ranked alongside such premier medical insti- 
tutions as Johns Hopkins and the Mayo Clin- 
ic speaks to the high caliber of our faculty 
and staff anil the high quality of our patient 
care." 

To be ranked, a hitspital had to meet one of 
three standards: be a member of the Council 
of Teaching Hospitals; be affiliated with a 
medical school; or provide at least nine out of 
1 7 prescribed technological services. These 
criteria winnowed the number of "rankable" 
medical centers in the United States from 
6.247 to 1.701. 

U.S. New.t ranked the top 50 programs in 
the following specialties: cancer; cardiology; 
digestive disease; ear. nose and throat; eyes; 
geriatrics; gynecology; hormonal disorders; 
kidney disease; neurology/neurosurgery; or- 
thopedics; pediatrics; psychiatry; rehabilita- 
tion; respiratory; rheumatology; and urology. 

LINC Hospitals" gynecology program 
ranked 14th nationwide. Pediatrics ranked 
22nd nationally — a first-time appearance on 
the list. 

■'How exciting it is that the reputation of 
our pediatrics department is garnering such 
prestigious acclaim just months before the 
opening of the new N.C. Children's Hospi- 
tal." said Alan Stiles, MD. chair of the De- 
partment of Pediatrics. "We have tried to 
establish a premier pediatrics program in 
North Carolina, and I think this ranking sup- 
ports our belief that we are succeeding in our 
endeawir." 

UNC Hospitals also appeared in the fol- 
lov\ing other specialty rankings: cancer. 41; 
digestive disease. 32; e;u", nose and throat, 26; 
geriatrics, 22; hormonal disorders. 24; kid- 
ney disease. 20; orthopedics. 37; respiratory 
disorders. I S; and urolocv. 24. 



Sanford Specialty Clinic 
Expands Services 

Just months following the opening of San- 
ford Specialty Clinics in Sanford. UNC 
Health Care has expanded its medical ser- 
\ ices. Sanford Specialty Clinic now offers 
endocrinology and osteoporosis care to its 
services that initially included pulmonary 
medicine and rheumatology. 

Pulmonary specialist Jana Johnson. MD. 
and rheumatology specialists Mary Anne 
Dooley. MD, and .Alfredo Rivadeneira, MD, 
provide patients medical care. 

Diagnostic and treatment services are 
available at the clinic for asthma, lung dis- 
ease, osteoporosis, rheumatoid arthritis, in- 
nammatory arthritis and tendonitis. 

The clinic, located at 212 W. Main St. in 
Sanford, is open from 8 a.m. to 5 p.m., Mon- 
day through Friday. Groundbreaking for a 
new facility is expected to take place this fall. 




Spicer-Breckenridge lecture 
focuses on medicine and art 

M. Tliere.se Soiillii^iile. MD, Senior 
Contributing Editor of the Journal iif the 
American Medical Association, was the 
keynote speaker at the 2000 Spicer-Breck- 
enridge Memorial Lecture, held May 5. 
Southgate presented "Some Affinities 
Between Medicine and the Visual Arts." 
Soulligate .selects covers and writes essays 
for JAMA, and she also lectures for med- 
ical societies, hospitals, museums, and 
cominunitx groups. 



UNC treats home health 
patients with the latest 
technology 

UNC Home Health has gone high-tech, 
thanks to a new program called Tele-Home- 
care that allows home-health nurses to 
"\ isit"their patients through telephones and 
computers. 

The technology of telemedicine isn't new. 
For years now, doctors ha\e consulted each 
other \'ia teleconference. And hospitals na- 
tionwide ha\e established telemedicine sites at 
satellite locations, allow ing doctors and pa- 
tients in rural areas to "meet" with specialists 
in more metropolitan areas. 

For UNC. though. Tele-Homecare repre- 
sents the first time the technology has been 
used to care for patients in their ow n homes. 

"We are only the second hospital in North 
Carolina to use Tele-Homecare." said Zelda 
Moore, a registered nurse and the program's 
coordinator. "East Carolina v\as the first, and 
they've primarily used it w ith patients who 
have congestive heart failure, hypertension 
and high-risk pregnancies. We'\e broken new 
ground by using it to care for wound patients." 

Using the new technology with wound pa- 
tients was a natural for the home health nurses. 

"These patients require a lot of monitoring, 
and we can spend a lot of time visiting them," 
Moore said. "With telemedicine we can still 
monitor the patients, keep the wounds healing 
and use our manpow er more effecti\ ely " 

Another plus for telemedicine is its tlexibil- 
it\. If a nurse is concerned that a patient is too 
sick for telemedicine care, the nurse can 
change the plan. 

"We can switch to home visits, or if we 
think the patient is too sick for home care, we 
can talk w ith the doctor about a clinic \ isit or 
other medical evaluation," she said. "A peifect 
example is the time 1 scheduled a Tele-Home- 
care V isit with a patient on a new medication. I 
noticed on the monitor that her face was 
sw ollen. so 1 Jumped in the car and went to her 
home for a more detailed assessment." 

Another related application for the technol- 
ogy is canng for bum patients. 

"Bum patients have to return so many times 
to clinic during their healing process." said 
Anita Fields, a registered nurse who is burn- 
care coordinator for the N.C. Jaycee Burn 
Center at UNC Hospitals. "Now we can use 
telemedicine to ease some of that burden." 



Research 
Briefs 



UNC, Duke, starting search 
for osteoarthritis genes 

It's not difficult to find :i laniilN in uhicli 
generation after generation has struggled 
with the same inherited disease. The chal- 
lenge is finding the genetic link to understand 
how illnesses, such as osteoarthritis, are 
passed dow n from parents to their offspring. 

An international research network com- 
posed of se\en uni\ersit\ medical institutions 
including L'.\C"s Thurston .Arthritis Re- 
search Center and Duke L'ni\ersit_\ Medical 
Center ha\e just begun the kirgest studs e\er 
to look for that link, the genetic susceptibilit\ 
to osteoarthritis. 

The most common form of arthritis, os- 
teoarthritis is a chronic condition that affects 
more than 21 million .Americans. Bs analw- 
ing DN.A and health histories from man\ pa- 
tients, researchers belie\e the\ will better 
understand the role that one or more genes 
play in the condition's development. The 
goal is to find nev\ and more effectix e medi- 
cines. The academic research institutions are 
working together u ith the Center tor Human 
Genetics at Duke and Glaxo Wellcome, a 
pharmaceutical conipan\. 

For the lull Stan. \ce lutp://\\\v\\.uin .cdu 
Au'us/newsscir/ivsccin li/i( inhiti 1 IJIOW.htiii. 

UNC opens first clinical trial 
of vaccine treatment for 
advanced breast cancer 

Doctt)rs at the Uni\ersity of North Caroli- 
na at Chapel Hill ha\e opened their first clini- 
cal trial of a \accine treatment for ad\anced 
breast cancer. 

.After more than four years of test-lube and 
animal studies, researchers at the UNC 
l.ineberger Comprehensi\e Cancer Center 
will find out if intra\enous infusions ot their 
genetically engineered protein fragments will 
stimulate a person's immune cells to recog- 
nize and kill breast cancer cells, causing ad- 
\anced breast tumors to shrink. 

"This breast-cancer \accine is not a shot - 
it's a 'vaccine' because it should work by en- 
hancing the patient's ovs n immune response 
against their tumor." said l.ineberger member 
Jonathan Serod\. .\11). associate prolessor of 
medicine antl microbiology and immunolo- 
gy- 

"This is the tlrst use ot a \accinc directed 
against a mollification ot a specific part of the 



HER-2/neu protein found on breast-cancer 
cells. People ha\e tried using engineered pro- 
teins in the treatment of melanoma, but not 
for breast cancer " 

Study: too much sugar, not 
enough milk may damage 
U.S. teens' health 

Between 19(1."^ and I ysift. a considerable 
shift occurred in the diets of U.S. teenagers 
that could compromise the future health of 
the nation's people, a major new Uni\ersit\ 
of North Carolina at Chapel Hill stud\ shows. 
On the horizon, researchers say. are more 
strokes, heart disease, high blood pressure 
and cases of the bone-weakening condition 
know n as osteoporosis. 

Total milk consumption dropped b\ close 
to 50 percent among adiilescents o\ er the 
three decades studied, they found. That de- 
crease was accompanied by a hea\ y increase 
in consumption of sugar-laden soft drinks 
and fruit-fla\ored beverages. Teens also 
began eating more of their \ egetables in the 
fiinii of fatt\ fried potatoes than their parents 
did. 

".An increase in high-fat potato consump- 
tion through French fries and hash browns 
led to an increase in segetable intake, but the 
number of ser\ ings of fruits and vegetables is 
still below the recommended fi\e per day." 
said Barr\ Popkin. PhD. professiir of nutri- 
tion at the schools of public health and medi- 
cine and one of the repint's authors. "Iron, 
lolate and calcium intakes continue tt) be 
below recommendations for girls." 

A report on the findings appears in the Jul\ 
issue of Archives of Disease in Childhood, a 
professional journal. 

hnp://\\\yu:iiiie.edii/iieu s/neu\ser\/ 
rese(ir(h/popkinS(l724()0.lilin 

Study seems to show >vhy 
French sutter less heart 
disease, cancer 

University of North Carolina at Chapel 
Hill scientists have discovered w!i\ a com 
pound found in grapes and grape products 
such as red wine shows natural cancer-figlu- 
ing properties that might be importanl in pre- 
venting or treating the illness. 

The work appears to explain (he sci-called 
"Irench |Xiradox" llic lad lliat Ircnch 



people experience lower rates of heart dis- 
ease death and certain cancers despite drink- 
ins: nu>re wine on averaize than L'.S. residents 
do. 

Scientists finind that the substance, irans- 
Resveratrol. or Res. modulates the activ it> of 
NF-kappa B. a protein that attaches to DNA 
inside cell nuclei and turns genes on and off 
like a svv itch, the scientists found. Res appar- 
entlx helps turn otf a natural protective mech- 
anism in the body inviilv ing the protein that 
prevents cancer cells from being killed, as 
thev should be. 

.A report on the work appears in the Julv 
issue o\' Cancer Research, a scientific jour- 
nal. .Authors are Minnie Holmes-McNary. 
PhD. a nutritional biologist and postdoctoral 
fellow at the UNC's Lineberger Comprehen- 
sive Cancer Center, and her mentor Albeil S. 
Baldw in Jr.. PhD. a biology professor who 
also works at the center. 

htlp://\\\\\\\itnc.edu/ne\vs/ne\\sser\/ 
researcli/hald\vin>l)63iH)l).htm 

New national study shows 
infection, fat embolism 
important contributors to 
sickle cell disease deaths 

Unusual infections and lumps o\ fat called 
emboli that clog arteries in the lungs appear 
to be under-appreciated causes of acute chest 
sv ndrome in sickle cell disease patients. The 
syndrtmie. which is a group of debilitating 
symptoms, is the leading cause of death 
among sickle cell patients, according to a 
major new studv . 

Earlier diagnosis and more aggressive 
treatment of those svmpioms might save 
many victims of the illness, which is the most 
common inherited disorder among black 
people in the United States, researchers sav. 

Improved treatment may include earlier 
use of oxygen, more eftective antibiotics, in- 
centive spirometiv and chest physical thera- 
py in patients who develop the chest 
syndrome, they say. When appropriate, earli- 
er use of blood transfusion and mechanical 
ventilation also should be considercti 

.A report on the .'^O-medical cciiici suulv 
appeared in the June 22 issue of the A'cir 
l:ni;land .loiirnal of Medicine. Listed among 
its authors was Fugene P. Orringer. MD. 
UNC professor of medicine. 

htlp://\v\\w.itnc.edu/ne\\ s/new sserv/ 
rese,n(h/orruf^\ll>')2liin.hnii 

17 



Alumni Profile 



Paul Viser Assumes 
MAA Presidency 



By Katherine Kopp 

Paul Viser, MD. recently installed as 
president of the UNC School of 
Medicine's Alumni Association, is a 
man v\ ith a sense of mission. 

■"r\e got two ver>' simple goals for myself 
as president," said Viser in a recent interview. 
"One is increasing membership in the alumni 
association. The second is increasing the sup- 
port, both tlnancial and in other arenas, that 
alumni contribute to the medical school." 

Viser. a native of Ahoskie and the son of a 
UNC class of "50. has found satisfaction fol- 
lowing in his father's footsteps. He graduated 
from UNC in l^SO with a bachelors of sci- 
ence degree in bicilogy. and credits the Biolo- 
gy Department with supplying him with 
more than just an undergraduate degree. "I 
met my w ife. Diane, in my biolog) class." he 
sa)'s w ith a laugh. "And for that reason alone, 
it was probably the best class I ever took at 
Carolina!" 

After recei\ ing his MD from the UNC 
School of Medicine in 1 984. Viser completed 
an internship and residency in internal medi- 
cine in Little Rock. Ark. Viser went on to 
spend two years in Whitesburg. Ky., fulfilling 
a National Health Ser\'ice Corps commit- 
ment. "Whitesburg is in the coal mining re- 
gion of Kentucky." explains Viser. "and there 
is a lot of poverty there. Working there was 
difficult in many ways, but it was also a very 
v\ orthw hile expeiience." 

After a brief sojourn in Winston-Salem. 
Viser. his wife Diane and their three children 
now enjoy quintessential small-town life in 
Clinton. "When it was time to lea\e Ken- 
tucky back in 1989. 1 looked at four different 
practice opportunities." says Viser. "I nar- 
rowed it down to two, one in Winston-Salem 
and one in Clinton, and we chose Winston- 
Salem. But after about six months, it became 
clear to me that I realh' missed small-tow n 
life. E\en though I was the fourth person in a 
great group of doctors in Winston-Salem. I 
just didn't feel it was the right fit for me." 

Viser realizes that the life that suits him so 
well is not for every physician. But he also 
believes that there are many benefits — both 
personal and professional — to being a 
small-town doc. 

18 




Ptiiil \'iM'r and son Aaron prepaic dinner 
for the rest of the family which includes 
Ellen. 1 1, and Mark. 8. 



"I know that some people think being a 
doctor in a small town is like being stuck out 
in the boondocks," he acknow ledges, "and I 
do miss the camaraderie I had as part of a 
group. Doctors who live in smaller tow ns and 
rural areas can sometimes get out of touch, if 
they don't keep up with reading journals and 
CME opportunities. But I've found that, even 
though I'm a solo practitioner. I share call 
with five other doctors and handle an acti\e 
hospital practice. It's a situation that's good 
for all of us." 

Viser shares office space w ith another 
physician right next to Sampson Regiiinal 
Medical Center, a land-grant hospital built 
after World War II and, according to Viser, 
one of the few independent hospitals left in 
the state. Though he li\'es in a town of only 
8,000 or so residents. Viser and the five other 
physicians he shares call with draw from a 
county population of 45.000 and beyond. 

"Clinton is in the center of Sampson 
County." Viser explains, "and 1-40 goes right 
through the county. By land area, we're the 
largest county in the state." 

Viser feels he has the best of all wodds — 
an independent solo practice, complemented 
by shai'ed coverage and some shared expens- 
es with other physicians, continuing educa- 
tion opportunities through UNC and other 



institutions that allow him to keep current 
with new advances, and life in a small-town 
where he is known and knows others. He is 
active in the community, doing everything 
from coaching softball to teaching Sunday 
schot)l to \olunteering on behalf of the 
Sampson Crisis Center, w hich pro\ ides food, 
clothing and shelter to those in need. 

He really enjoys the bonds that he has de- 
\eloped w ith his fellow citizens in Clinton. "1 
thri\e on the relationships that have devel- 
oped," he says. "These relationships, with pa- 
tients and with those in the w ider community, 
develop slowly, over a period of time. You 
just can't rush them." 

Viser stays busy, seeing about 1 5 to 20 pa- 
tients a day — "within the norms for in- 
ternists." he says — rounding at two nursing 
homes and making occasional house calls. 
"My dad used to carry a big doctor's bag on 
his house calls." Viser remembers. "He car- 
ried everything you could think of: it was big 
enough for a camping trip!" 

"If a patient is tenninally ill or just got out 
of the hospital." he says, "it's nice for me to 
gi) to them and see how they're doing. That's 
often hard to do in a practice in a larger 
town." says Viser 

An avid and lifelong learner, Viser is con- 
stantly reading journals, discussing cases 
w ith other ph>sicians. and attending confer- 
ences to improN e his base of know ledge. 

As president of the Alumni Association. 
Viser plans to stay on his toes for the rest of 
his tenn. "I hope to encourage more people to 
attend our medical alumni weekends," he 
says. "They're a great opportunity for contin- 
uing education, and an even better opportuni- 
ty just to see one another and catch up." 

He also hopes to increase the le\el of fi- 
nancial participation by graduates of the 
medical school. And Viser, who is not afraid 
to put his money where his mouth is, has 
gi\ en regularly to the UNC School of Medi- 
cine. "I spent eight very iinportant years of 
my life in Chapel Hill," says Viser. "I owe my 
li\ ing to that, and I'd like to do what I can to 
encourage a feeling of loyalty and gratitude 
toward the Medical School among my fellow 
alumni." D 



Match Day 



^^^Kj ^ '* laP 




^^Pr <^V 


^^H 




»^::i 



CotiiiralulaluMis to the Class of 2(K)() School ot Medicine gradu- 
ates. Nearl\ half ot the graduates entered a priniar\ caie residencs 
program earlier this summer Check the list bekm lor the names of 
residents coming to your program. Then, call them with a u elcome 
loyourcitN ortown. 

Visit the School ol Medicine Web site at 
uw'M.niCil.uiu .cdu/Mi/iinnch/lii.srory lor more mlormation on 
this and piexious matches. Those listed belou and on the Web 
consented for their names to appear in public documents. 



iforn 



Alabama 

William Trac\ Durham 

California 

Carols n Cell 
Karen Marie Di\on 
Susan Hunter Gibbs 
Har\e\ James Hamrick. Jr. 
Da\ id Laurence Issacs 
Catherine Tung-Ling Lee 
KimberK Susan Le\in 
Madelena Michele Martin 
Louise Dysart Met/ 
Zackary .S Moore 
Nimesh Bhupendra Shah 
Elizabeth .\ Steele 

Colorado 

.•\llison Dorbandt 

District of Coliinihia 

Katina Cieiger Barnes 
Romulo Ernesto Colndres. Jr. 
Nerissa .Marge Price 

Florida 

OluwatoNin Olarele .Ajose 
.Mehin .Standford F-arland. Jr. 
Sonja Trojak F-'rance 
SamerTaj-Eldin 
Johann Vincent Torres 

(k'orgia 

Sung K>u Chang '^I'i^Hl 

Illinois 

Zane Kesin Basrawala 
Lisa Rahangdale 
Taslor Hainer Stroiul 



Indiana 

Donald Lee Mcl.amb. Jr. ' n/!i/in/i 
Michael Patrick Murphy "'"<'"^' 



Internal Medicine 



Pediatrics 

Emergency Medicine 

Internal Medicine 

Medicine 

Radiology-Diagnostic ( Ad\. ) 

Transitional* 

Emergenc) Medicine 

Pediatrics 

Internal Medicine 

Pediatrics 

Psychiatry 

Anesthesiology (Ad\.) 



let of 



Pediatric 



Pediatrics 

Pediatrics 
Psvchiatrv 



Pediatrics 
Family Practice 

Pediatrics 
Internal Medicine 
Medicine-Pediatrics 



Medicine-Primarv 



Urology 

Obstetrics/(i\necolog\ 
Radiolosjv-Diag. , 



Emergency Medicine 
Emergency Medicine 



Colo 



Vn\\. Alabama Hospital. Binningham 



Childrens Hiispital. Oakland 
.Alameda Counts Medical Center. Oakland 
UC San Francisco. San Francisco 
UC San Francisco. San Francisco 
UC San Diego Med. Clr.. San Diego 
Santa Clara Valle\ Medical Ctr.. San Jose 
Stanford Uni\ersit\ Programs. Stanford 
Loma Linda Univ. Med. Ctr. I.oma Linda 
VC San Francisco. San Francisco 
Stanford Uni\ersit\ Programs. Stanford 
Loma Linda Uni\. Med. Clr. Loma Linda 
Stanford Unixersitv Programs. Stanford 



Colorado School of .Medicine. Denver 



NCC- Walter Reed Arm\ Medical Center 
Childrens National Medical Center 
Georgetown llni\crsit\ Medical Center 



Jackson Memorial Hospital. Miami . , 

Florida Hospital. Oriando > ^1''' 

Uni\. Florid;i/Shands Hospital. Gainesville 
Uni\. Florid.i/Shands Hospital. Gaines\ille 
Jackson .Memorial Hos|iital. Miami 



Emopv Uiii\ersii\, .Atlaiila 



Loyola Uni\. Medical Ctr.. Mawvood 
McCiau Medical Ctr Northuesiern. Chic; 
Unnersitv ot Chicago Ho.pnal 



Indiana Uni\.. Imlianapolis 
Indiana Uni\.. Indianapolis 



19 



Kentucky 

Andrew Craig McGregor nfiif^l 

Maine 

Kimberly Lyn Hartnett 

Maryland 

Janinc Elizabeth Billiard 

William Aycock Mills, Jr. 

Patrick O'Connell Mctr 

Michigan 

Leslie Renee Ellis 
Mark Eric Hutchin 
Mark Eric Hutchin 

Minnesota 

JetTrey Schiller Mueller 

James Elliot Rider 

Leonide Gerard Toussaint III 

Massachusetts 

Bi7an Courtney Batch 

Sandra Charlotte Farkouh 

David Laurence Issacs 

Stephen Andrew Oljcski 

Aneesh Kiuiiar Singia 

Peter Anton /.emaif \laSSach 

New York 

Michael L;iJaun Cody 

Kendreia Wynette i^ickens-Williams 

Albert Hamilton Holt. Jr 

Jenniler [illen Larson 

Stephen William North 

Patrice Lanette Reives 

Elizabeth Cate Roede 

William Douglas Schell 

North Carolina 

James Ritbert Alexander 
James Robert Alexander 
Albeil Muir Leonard Anderson 
Frederic|ue Claude Marie Bailliard 
Anne Wood Bea\'cn 
JetTres \i. Brow n 
Donna Michelle Capps 
■Abigail Suzanne Caudle 
Chanhthevy Sourisak Chai 
Kimberley Renette demons 
Kelli Gail Coop 
Patricia .Ashles Coppatie 
David Rodolph Dixon^ 
Brian William Downs 
Brian William Downs 
Cescili Aurelia Drake 
Myriam Ruth Farkouh 
William Mortimer Fowlkes IV 
Carolyn Lonaine Hess 
Shawn Brooke Hocker 
Carolina Markey Hoke 
Tenence Edward Holt 
Jennifer Ann Hooker 
Tracy Powell Jackson 
Skyler Elizabeth Kalady 
Sosena Kebede 
Dennis John Kubinski 
Ke\ in Michael Lee 
Bartholomew Joseph Lopina 
Kecha .AnnMarie L\ nShue 



Uroloiiv (Adv. 



General Surcerv 



Pediatrics 
Pediatrics 
Medicine-Primary 



Internal Medicine 
Surgery* 
Otolaryngology (Adv. 



Radiology-Diag. (Adv.) 
Internal Medicine 
Neuroloiiical Sure. (Adv.) 



Internal Medicine 
Pediatrics-Primary 
Medicine* 

Radiology-Diag. (Adv.) 
Anesthesiology (Adv.) 
Urology 



Anesthesiology (Adv.) 
Obstetrics/G\'necology 
Psychiatrv 
Internal Medicine 
Family Practice 
Psychiatry ' 

Obsletrics/Gynecology 
Orthopedic Surge!7 



}or 



Medicine* 

Phy. Med/Rehab(Adv.) 

Medicine-Primai7 

Pediatrics 

Internal Medicine 

Internal Medicine 

Family Practice 

General Surgery 

Family Practice 

Anesthesiology 

Internal Medicine 

Pediatrics 

Family Practice 

Otolaryngology (Ad\. ) 

Surgery* 

Obstetrics/Gynecology 

Pediatrics 

Emergency Medicine 

Family Practice 

Orthopedic Surgery 

Obstetrics/Gynecology 

Internal Medicine 

Orthopedic Surgeiy /Research 

General SurgeiT 

Pediatrics 

Internal Medicine 

Lrology (.Adv.) 

Internal Medicine 

Family Practice 

Pediatrics 



Uni\ . of Kv. Medical Center. Lexington 



Maine Medical Center. Portland 



Johns Hopkins Hospital. Baltimore 
Johns Hopkins Hospital. Baltimore 
Johns Hopkins Bay\ iew Med. Ctr., Baltimore 



Univ. Michigan Hospitals. Ann Arbor 
Univ. Michigan Hospitals. Ann Arbor 
Univ. Michigan Hospitals. Ann Arbor 



iigan 



Univ. Minn. Medical Scht)ol. Minneapolis 
Univ. Minn. Medical School. .Minneapolis 
Mayo Graduate School ol Medicine. Rochester 



Boston Uni\. Medical Center 

Boston Combined Peds Res. Program, Boston 

Mt.Aubuni Hospital. Cambridge 

New England Med. Ctr. Boston 

Mass. General Hospital, Boston 

Boston Uni\. School of Medicine 



St. Vincents Hospital. New York 
MetiX)politan Hospital Center. New York 
New York Uni\ersit\ Medical Ctr. 
LIniv. Rochester/Strong .Memorial. Rochester 
Univ. Rochester/Strong Memorial, Rochester 
Long Island Jewish Med. Ctr., New Hyde Park 
New York Presbyterian Hospital, New York 
St. Lukes-Roosevelt Hospital Center, New York 



Carolinas Medical Center, Charlotte 

Carolinas Medical Center. Chariotte 

Duke Univ. Medical Ctr., Durham 

UNC Hospitals, Chapel Hill 

UNC Hospitals. Chapel Hill 

Moses Cone Memorial Hospital. Greensboro 

Mountain AHEC. AsheviUe 

UNC Hospitals. Chapel Hill 

UNC Hospitals, Chapel Hill 

UNC Hospitals, Chapel Hill 

Carolinas Medical Center, Charlotte 

Carolinas Medical Center. Charlotte 

Wake Forest Uni\. Baptist Med. Ctr. Winston-Salem 

UNC Hospitals, Chapel Hill 

UNC Hospitals. Chapel Hill 

Duke Univ. Medical Ctr. Durham 

UNC Hospitals, Chapel Hill /. /^.-/i-/^//; 

Uni\. Hllh System East Carolina, Greenville 

Carolinas Medical Center. Charlotte 

Duke LIniv. Medical Ctr. Durham 

UNC Hospitals, Chapel Hill 

UNC Hospitals. C hapel Hill 

UNC Hospitals. Chapel Hill 

UNC Hospitals. Chapel Hill 

UNC Hospitals. Chapel Hill 

New Hainner Regional Med. Ctr. Wilmington 

Wake Forest Uni\. Baptist .Med. Ctr, Winston-Salem 

UNC Hospitals, Chapel Hill 

Wake Forest Uni\. Baptist Med. Ctr., Winston-Salem 

Carolinas Medical Center, Chariotte 



20 



Alycia Moore McFarland 
Christopher Brent Mizelle 
Christopher Brent Mi/elle 
Joseph Albert Molitiemo. Jr 
Joseph Albert Mohtiemo. Jr. 
Jaquelin Marie Xash 
Jaquelin Marie Nash 
\\'end\ Gail Owen 
Heather N. Roberston White 
KiniberK Miehelle Rouse 
Vineent Cyril Schooler 
Karen B Stitzenberg 
Melanie L\ nn Tew 
Am\ Jacqueline Tn\ ette 
John W. Watts 
Jonathan Bradle\ W'otxls 
Matthew Donald '"lount; 



Psychiatn 
Dermatology (Adv.) 
Medicine* 
Surgery* 
Urolog) (.Ad\.) 
Demiatolog\ ( .Ad\'. ) 
Medicine* 
Medicine-Priniar) 
()bstctrics/G\ necolosj 
Family Practice 
Internal Medicine 
General Surger> 
Psychiatr\ 
Psychiatr) 
FamiK Practice 
Medicine-Primary 
L'rolos:\ i.Adv.J 



UXC Hospitals. Chapel Hill 

LNC Hospitals. Chapel Hill 

Moses Cone .Memorial Hospital. Greensboro 

CNC Hospitals. Chapel Hill 

L'NC Hospnals. Chapel Hill 

UNC Hospitals. Chapel Hill 

UNC Hospitals. Chapel Hill 

Duke L'ni\. Medical Ctr.. Durham 

Carolinas Med:cal Center. Charlotte 

New Hamner Reg. .\led. Ctr,. W'ilmnigton 

Wake Forest Univ. Baptist Med. Cti . \\instoii-Salem 

UNC Hospitals. Chapel Hill 

LNC Hospitals. Chapel Hill 

LNC Hospitals. Chapel Hill 

Mountain AHHC. Ashe\ ille 

Wake Forest L'niN. Baptist Med. Ctr.. W iiiston-Salem 

Duke L'iii\. .Medical Ctr.. Durham 



Pennsylvania 

Megan Ha_\es Bair-Merritt 

LaTos a A. Brow n 

LaToN a .A. Brow n 

Timolh\ Ward Dancy 

Da\ id P. Fit/gerald 

Elizabeth Leonard Fit/gerald 

Corey D. Fogleman 

Melinda Diane Frit/ 

Seth Chnstopher Collings Hawkins 

Jeffrey Schiller .Meuller^ 

Deepa Perumallu 

Douglas Da\ id Rockacy 

.Amish Chandrakant Sura 



Pediatrics 

.•\nesthesiolog\ (Ad\. ) 
Transitional* 
Famil> Practice 
Internal Medicine 
Pediatrics 
Family Practice 
Pediatiics 

FmergencN Medicine 
Transitional* 
Internal Medicine 
Emergence Medicine 
Internal Medicine 



Childrens Hospital of Philadelphia 
Hospital ol the L'ni\ ol Pa.. Philadelphia 
Frankford Hospital. Philadelphia 
UPMC Shads side. Pittsburgh 
Hospital ol the Linn. ol'Pa.'^ Philadelphia 
Childrens Hospital of Philadelphia 
Lancaster General Hospital. L,ancaster 
Llni\. Health Center of Pittsburgh 
Lini\ . Health Center of Pittsburgh 
L!ni\. Health Center of Pittsburgh 
Hospital of the Univ. of Pa.. Philadelphia 
L'ni\. Health Center of Pittsburgh 
L'ni\. Health Center of Pittsburgh 



South Carolina 

Tro\ .Augustus Bunting 
Bamab\ Todd Dedmond 
Zane Ian Lapinskes 



Internal Medicine 
Orthopedic Surgen. 
FamiK Practice 



Medical Uni\ . of SC. Charleston 

Palmetto Richland Mem. Hiispital. Columbia 

Self Memorial Hospital. Greenwood 



Tennessee 

Michael Thomas Capps 
Seth Monis Cohen 
Peter Howard McHu'jh 



Medicine-Pediatrics 
Otolaryngology (Adv.) 
Medicine-Pediatrics 



Vandcrbilt Uni\. Medical Ctr.. Nash\ ille 
Vaiidcrbill Univ. Medical Ctr.. Nashxille 
L'nn. Tennessee COM. Memphis 



Texas 

Janet Eli/abelh Hams 
Dawn Denise Johnson 
Jason Neil Kat/ 
Susan Lee Marcelli 
Tans a Pauline Tiamfook 



Obstetrics/G\ nccolog; 
Pediatrics 

Emergency Medicine 
Obstetrics/G_\ nccolog; 
FamiK Practice 



Univ. Texas Med. School. Houston 
Uni\. Texas Southwestern Med. Schiiol. Dal 
L'ni\. Texas Southwestern Med. School. Dal 
Baylor College of Medicine. Houston 
Uni\. Tc\as Med. Branch, (iabcston 



Robert Stuart B\rum 
Chris D Fennelf 
Erie hars Franckc 
Traces Louise Huckabec 
MokhtarO. .Morgan 
Scott Da\ id .Nash 
Michael Karim Newman 
Stephen Andrew Oljcski 
Jonathan R Saluta 
Yalaunda .Michelle Ihoma' 
James Eric Turner 
R\an Carl Wanamaker 



\\usliin)it<)n 

.Neil C \ iniHL' 



Internal Medicine 
.Anesthesiology 
Orthopedic Surg.-fith M-ar 
FamiK Practice 
FamiK Practice 
Medicine-Pediatrics 
Plastic Surgery* 
Transitional* 
Orthopedic Surgen 
Surger\ * 
Internal Medicine 
Medicine-Primary 

Oilhopcdic Surgery 



Liniversity of Virginia. Charlottcs\illc 
L'ni\ersit\ of Virginia. Charlottesv ille 
I 'ni\ersity of Virginia. Charlollcs\ ille 
Chippenham Medical Center. Richmond 
Rixcrsidc Regional Med. Ctr. Newport News 
Medical College of Virginia. Richmond 
Medical College of Virginia. Richmond 
Carilion Health S\stem. Roanoke 
Mctlical College of Virginia. Richmond 
Uni\ersiiy of Virginia. Charlottes\ illc 
L'ni\ersiiy of Virginia. Charlottes\ille 
L'ni\ersii\ of Virginia. Charlottes\ille 



Madi'jan Arniv Medical Center. Tacoma 



Alumni 

Notes 



50s 



William S. Jovner, MI) "50. recently 
mo\ed to the nevvlv opened Croasdaile 
Methodist Retirement Community in 
Durham, and writes that he and wife 
Jane are doing their best to keep the 
UNC Hag flying in the shadows of the 
Duke campus. 

Dan A. Martin, MI) "50, is still engaged 
in his work as director of Trover Clinic 
Foundation Education Division and as 
medical director of the Hopkins County 
(Kentucky) Health Department. Martin 
can be reached at kymartinsC? \ci.nct. 

John L. McCain, MD "50. is the medical 
director of three nursing homes, in addi- 
tion to his practice in rheumatology and 
geriatrics. McCain writes that he is enjoy- 
ing his practice a great deal — he went 
solo in "92. moved into a new office in 
"98. and became a certified medical 
director in "98. McCain and wife Betty 
li\e in Wilson. NC. 

IJoyd C. McCaskill, MD "55. joined his 
cousin. Norman McCaskill. along with 
their wises and families last April in the 
dedication of the UNC-CH McCaskill 
Soccer Center by the UNC Athletic 
Department and the Educational Founda- 
tion. McCaskill's family of UNC gradu- 
ates includes Norman McCaskill. "33: 
Lloyd C. McCaskill. '51 and "55; L. 
Curtis McCaskill. Jr. "78: Donna Jordan 
McCaskill. "TS: T. Gray McCaskill, "79; 
Kimberly Davis McCaskill. "80: Janell 
McCaskill Hannah. "83: Roger D. 
Hannah, "79: and future graduate James 
Curtis McCaskill. Lloyd"s grandson, a 
sophomore. 



60s 



emerald (Jerry) Fernald, MD "60. 

remains acti\e in resident recruitins: for 



the department (if pediatrics and the F.W. 
Denny Society at UNC. 

Frank McCain, MD "60. has two part- 
ners now after 35 years of solo allerg\ 
practice. McCain works 4 days each 
week and says that he is enjoying his 
work more than ever, because having the 
partners affords him more time with his 
patients and less stress. 

G. Thomas Strickland, MD "60. says 

he has no plans to retire anytime soon — 
he still enjoys teaching medical and 
graduate students, house officers and 
health care pro\ iders in practice. 
Strickland has research projects ongoing 
in Mar\land, Brazil, the Philippines 
and Egypt. He and wife Anne li\e in 
Baltimore, and can be reached at 
tstrickland@som.umar\ land.edu. 

Robert L. (Jrubb, Jr., \ID "65. is heavi- 
ly involved in bitth clinical neurosurgery 
at Washington University in St. Louis and 
in research using PET scanning to 
patients with severe head injuries. 
Grubb's wife, Julia, is vice-president of 
the Friends of St. Louis Children's Hos- 
pital and serves on the board of directors 
of Epworth Children's Home in St. Louis. 
His son. Robert III. is a fourth-year urol- 
og\ resident at Barnes-Jewish Hospital, 
and daughter Mary Connell is a first-sear 
law student. 

Robert Kindley, MD "65. retired from 
the .Air Force m 1996. after 22 years. 
Kindley is now in private allergy practice 
in the Destin-Ft. Walton Beach area of 
Florida. He and w ile Lynn can be reached 
at rkindle\'(?' aol.com. 

WIMiam F. Savers, MD "65. retired in 
January of this year. He and wife Bett\ 
arc looking forward to spending more 
time at Bald Head Island. NC. and 



Iraseling. They can be reached at 
wsayers(n triadiT.com. 

F. Walton .\very, MD "67. retired from 
pathology practice in July "99, and 
recently returned from a vacation in 
Israel — a trip that he says is a must for 
e\er\one. 



70s 



Stephen L. Green, MI) "70. has started a 
charils called Sedona LTD. dedicated to 
bringing AIDS care to the Caribbean and 
Central .America. 

John F. Hanna, MD '70. retired from 
otfice urologs practice in Louisburg. NC . 
in 199S and mo\ed to Sarasota. Fla. 
Hanna writes that he is doing real estate 
and property management in a hot mar- 
ket, and doing better than ever in medi- 
cine, w iih a lot less stress. 

Bruce Berlow, MD "75. moved to 
Mystic. Conn., two years ago after prac- 
ticing in Santa Barbara. Ca. for 18 years. 
He and w ife Lee can be reached at 

bbcrlow (n pol.nel. 

Frank Moretz, MD "75. is currently the 
secretary treasurer for the N.C. Society of 
.Anesthesiologists. Moretz is slated to be 
president of the NCSQA in 2002. 

F;d Morris, MD "75. received a PhD in 
philosophy in 1998. and is currently 
leaching philosophy part-time. Morris 
enjoys running, and has completed six 
marathons, including two Boston 
Marathons. 

Cynthia D. Conrad, MD "78. has a new 
position vsith Connecticut Valles Hospital 
(the state's long-term psychiatric hospi- 
tal) as Chief of Professional Ser\ices. 



She has spent the past 13 \ears associated 
with the Institute ot Li\in>; in Hartlord. 



80s 



Lawrence Wyner. MD '83. is a leiial 
transplant surgeon at Chariestt>n Area 
Medical Center in West Virginia. He and 
his wife. Louida. announce the birth ol 
their second child. Tessa Anneliese. u ho 
was horn No\. 30. 1999. Their son. Joshua 
Ross, celebrated his third birthda\ in Jul\. 

Sebastian R. .Alston, MD '85. is cunent 
ly an associate protessor ot patholog} at 
Mercer Uni\ersity School of Medicine in 
Macon. Ga. Alston says he is having a lot 
of fun at Mercer, and he currentl\ serves 
as secretary of the Group for Research in 
Pathology Education (GRIPE), the pathol- 
ogy education association. 

Leslie .\. Bunce, .MI) '85. reports that 
alter nine years in academic hematolog\/ 
\ascular medicine at the Uni\ersity of 
Rochester and two and a half \ ears in 
pharmaceutical medicine in Research 
Triangle Park. .NC. she recently began 
an open-ended hiatus to enjo\ time at 
home with her two sons. Michael. 6. 
and .lames. 4, 

Elizabeth Kngelhardt .Mandell. .MD '85. 
her husband. Jim. and children Michael. 
6. and Kaitlyn. 3. recently mo\ed to the 
Minneapolis/St. Paul area in order to be 
closer to Jim's job as a pilot for .Northwest 
Airlines. Mandell is currently interview- 
ing for jobs and plans to continue her 
practice in occupational medicine, 

Terrence (Sonny) .M(irt(in, MD '85. is 

currenti) practicing coiiimumt_\ hospital 
emergcncN medicine, and expects to com- 
plete a dual .MBA / MHA degree program 
next spring. 



active with a group of pediatricians from 
her hospital who volunteer their serv ices 
to children in El Salvador. Thomas says 
she finds the work very rewarding, and 
recommends physician volunteerism to 
aiivone suffering from "phvsician hurn- 



Marilyn Russell, PhD '86. is an adjunct 
pritfessor of biologv at Gonzaga Universi- 
tv. in Spokane. Wash. Russell says she 
enjov s raising her granddaughter. Angela, 
renovating her farmhouse and l.^-acre 
farm, and raising organic vegetables m 
her greenhouse year-round. 

Michael Duggan, MD '88. and his w ife. 
[-aura, lecentlv celebrated the birth of 
their second son. Luis Raphael. Their 
son Max Perez is 6 years old. Duggan is 
a pathologist w ith Pathology Medical 
Services in Lincoln. Neb. 

Philip Thwing, MD '88. is proud to 
announce his engagement to LcAnne 
Keicher The two were to be married in 
Julv. His email address is: 
PhilThwinu a Greene. \tn. net. 



90s 



lodd Cowdery, MD 'y(». lues and works 
in the San Juan Islands of Washington 
State on an island called Orcas. Cowdery 
serves the communilv as a familv phvsi- 
cian. He reports that Orcas is roughlv the 
si/e of Manhattan, but with only 1/1 OOO'*^ 
the population. A critical difference, he 
notes, to he and his two partners who pro- 
vide the island's onh 24/7 medical care. 
Cowderv relies on the consiaiu compan- 
ionship of his dog. Jericho, whom he 
calls a dog with a remarkable travel (ale. 
Cowderv can be reached at: 
tcovi,derv (" rockiskuufcom. 



a PhD from Medical College of Virginia 
in 1998. He is current! v in a cardiotho- 
racic surgerv fellow ship at Hahnemann 
Universilv Hospital m Pennsv Ivaiiia. 

Gary M. Myles, PhD '90. graduated liom 
law school at the Universitv of Washing- 
ton in June "99. Myles is now an associate 
patent attomev at Seed Intellectual Prop- 
erty Law Group PLLC. a chemical/ 
hiotechnologv practice in Seattle. 

Todd (Jriffith. MD '97. has begun a 
nephrology fellow ship at Duke L'niversiiv 
Medical Center Griffith, his wife. .Andie. 
and their two children are excited to be 
returning to the Triangle. Thev can be 
reached at :todd.i:ri filth Cp alumm.diike.edu. 



Deaths 

.k'rr> F. Kriigh, MS. PT '84 



Claudia Ihomas. Ml) '85. 



.urrenllv 



.John ( Iriv I Liit«istle. Ml) '9(» uceived 



23 



Development 

Notes 



Loyalty Fund Campaign 




Rciininn aiul ivfiioiuil committee chairs presented more than $S22.()Ol) in 
Loxaltx Fund donations at the Sprint; Medical Alumni Banquet in 
Chapel Hill. Final aunpaign totals for the year ending June 30. 2000 
are listed helow. 





Number of 


Percent 


Total Cash 


Class/Region 


Volunteers 


Participation 


& Pledges 


Class of 1945 


3 


16/24(67%) 


S 6.8(X) 


Class of 1950 


11 


32/39(82%) 


$ 20,000 


Class of 1955* 


23 


44/48 (92<7r) 


$150,500 


Class of 1960 


24 


35/60(59%) 


$ 40.000 


Class of 1965 


12 


24/54(44%) 


$ 14.000 


Class of 1970 


12 


31/69(45%) 


$ 30.000 


Class of 1975 


TT 


34/100(34%) 


$ 168.500 


Class of 19S() 


10 


50/153(33%) 


$ 19.000 


Class of 1985 


15 


37/143(26%) 


S 24.000 


Class of 1990 


24 


45/125(36%) 


S 13.500 


Class of 2(X)0* 


20 


1 16/13()(89%)(,n,./,U,n/v 


S 25.525 


Atlanta*** 


10 


43/108(40%) 


S 14.000 


BLincoiiihe*** 

.\shcyille 

Durham/Orang 


12 


29/67(43%) 


$ 16,500 


e 18 


124/343(36%) 


S 63.500 


Forsyth 


21 


51/100(51%) 


$ 33.(X)0 


W'inston-Salenr 








Guilfoi'd 
Lheenshoro 

Mecklenburg 


28 


103/174(59%) 


$ 49.500 


25 


86/217(40%) 


$ 60.000 


Charlotte 








New Hanoser 


14 


41/70(59%) 


S 35.200 


Wilnungton 








Wake 


25 


106/276(38%) 


S 39.300 


Raleigh 








'irpn'Hiil'. /i(i,'/iCA 


level i>t iiliinini piu 


tieipcititinin elci.'.s. 




**Foiirth-yciir CiiiniHiiiiii reuclied all- 


time hii:h ii/z/i S9'", purlieipiHidn. 




* * *Ccisli only, iwl including pledges 







Hatcher Golf Tournament 
scheduled 

The 2000 Mike Hatcher Memorial Golf 
Tournament kicks off w iih registration at 1 1 :30 
am. on Monday. Oct. 9. at Prestonwiiod Golf 
and Country Club in Cary. 

The shotgun start will he at I p.m. Cost is 
S 1 50 per golfer, w hich includes a charitable 
contribution of S65. 

The tournament raises money for cystic fi- 
brosis research at UNC. Since the e\ent started 
four years ago. it has raised more than 
$200,000. Last year, there were appro.ximately 
300 entrants. 

To enter, contact Greg Hatcher, tournament 
director, at (919) 469-3868 or 310-9758 
( pager) or email ghatcher(5' ix.netcom.com. 

Or. contact Jim Miller at The Medical 
Foundation of North Carolina. Inc. at (919) 
966-1201 oremailjim_miller(? unc.edu. 

Honor Roll of Donors . ' 

Correction 

The Winter 1999/2000 issue of the Bulletin 
included the Medical Foundation's annual 
"Report to Donors." which features an Honor 
Roll of Donors who made contributions to the 
Loyalty Fund during the preceding fiscal year. 
L'nfonunately. not all names were included in 
the Loyalty Fund List. Our apologies to those 
donors v\ hose names appear below : 

• J.AllenWhitaker.M.D. "31 
Rocky Mount. NC 

• JackB.Hobson.M.D. "57 
Charlotte. NC 

• Robert S.Cline.M.D. "57 
Sanford. NC 

• Robert J. Cowan. M.D. "63 
Winston-Salem. NC 



24 



President's 
Letter 



As I dro\e to Chapel Hill in Ma\ lo 
piirticipate in the graduation cero- 
nion\ tor the Sehool of Medi- 
cine's Class ot 2()()(). I was 
alread) excited about m\ being inxited to 
participate. 

Just 16 \ears bexond ni\ own gradua- 
tion in that same Memorial Hall, the memo- 
ries ot" it all remained \ i\ id. The e\ ent 
marked one otlhe tlnal academic milestones. 
w ith the presence ot Tamily and close friends 
adding due weight lo the occasion. It was at 
once a celebration and a good-bye to class- 
mates before scattering hither and yon. With 
an idea of w hat lay ahead for this year's class. 
1 shared the electricity of the eager graduates. 
.As Dean Smith said in his often-imitated un- 
emotional nasal twang amid the immediate 
aftermath of the UW2 championship. "I am 
happy for our seniors." (The next year, you 
recall. Jim VaKano demonstrated how to cel- 
ebrate as he spun around the court in Brow n- 
ian motion!) 

Anyway, as it turned out. graduation day 
this time around was notable more for the 
time Just before the ceremony. Having re- 
ceived by mail my parking placard, my mind 
was free as I cruised into tow n vv ith about 
30 minutes to spare. From a radius of a mile 
or so. I started to see cars double-parked on 
the major thoroughfares. Closer to campus, 
centripetall-obese fathers, red-faced and 
soaked with sweat, were struggling uphill 
along the sidewalks as their perky gow ned 
daughters set the pace. Closer still, the 
swarms of humanity required me to slow 
down to walking speed, (inally I approached 
the Columbia .Street-Cameron A\enue inter- 
section where the hallowed path to the Old 
Well was blocked. A barricade was manned 
by three people, including an armed police 
officer, but a simple wa\e of my parking 
placard got for me a smile and a welcome 
through. 

As I inched toward Memorial Hall, gently 
easing my way through groups of people 
standing on the pa\ement. it was plainly ap- 
parent that I was one of the \ery lew allowed 
to pass that way. Moments later. 



GniUtiidc 

Tlw liii;li pri:f of lite, ilic ndwiiiiii; tcrtiiin 

(>l (I mail, is u> he horn with a hias u> sonic 

pitisnit which finJ.'i him In employment 

iiihl luippincss. 

Ralph W'alilo F.mcison 



I parked within .SO teet of the aLidiloiium 
where, incidentally, there \\ere another 
15 empty spaces. Without question, that was 
the highlight of my Tar Heel career 

Other e\ ents come to mind — getting an 
.A in organic chemistry, being oflered a seal 
in medical school. e\en getting midcourt 
bleacher seats in Carmichael tt)r the Caroli- 
na-Duke game — but none of these approach 
the ie\el of my special parking pri\ilege as 
president iif the UNC Medical Alumni 
Association. 

For the parking space and for the eight 
wonderful years at Carolina, I am deeply 
grateful. Having received a top-le\el educa- 
tion at nominal cost. UNC deserves my life- 
long loyalty and support. Since each of you 
shares w iih me this legacy of pri\ ilege. I urge 
you to join me in meeting our responsibilit\ 
to give something back lo our alma mater. 
Refer your patients. Connect w ith your fel- 
low alumni at the various social functions 
and CME"s. Precept a student. Become a 
Loyalty Fund associate. Look for wa\s to 
build up our School of Medicine as so maiiv 
before us havetlone proudly. 





CME/Alumni Calendar 

September 15-17. 2000 - Kingston Plantation. Myrtle Beach. SC 

N.C. Society of Anesthesiologists Fall Session 

September 16. 2000 - Chapel Hill 

Family Day / While Coat Ceremony 

September 22-23, 2000 - Chapel Hill 

I'NC Wound Management Conference 

September 2S-30. 2000 - Chapel Hill 

Ross Society Annual Meeting 

October 3. 2000 - Chapel Hill 

Dedication of Neuroscience Research Center 

October 6-7. 2000 - Durham 
UNC Children's Burn Conterence 

October 10. 2000 - Chapel Hill 

Berryhill Lecture 

October 13-14. 2000 - Greensboro 
UNC-Duke Women's Cancer Conference 

October 20-21. 2000 - Chapel Hill 

Fall Medical Alumni Weekend 

For more information about CME courses, contact the Office of 
Continuing Medical Education at (919) 962-21 IS or toll-free 
through the Consultation Center at (800) 852-6264. To contact 
the Alumni Affairs Office, call (919) 962-6786 or email 
medical alumni Cp nied.unc.edu 



m'^^'M 



Estate Planning Notice 

Many individuals would like to make a major gift 
to the UNC medical center, but cannot commit 
current assets for such a purpose. Through a will, 
however, anyone can make a more significant gift 
than they might ever have thought possible by 
designating a specific sum, a percentage, or the 
residue of their estate for the benefit of the medical 



To provide a bequest, simply include a paragraph 
in your will naming The Medical Foundation of 
North CaroUna, Inc. as a beneficiary. For example: 

"I give, devise and bequeath (the sum of$ 

or ( % of my estate) or (the residue of 

my estate) to The Medical Foundation of North 
Carolina, Inc., a 501(C)(3) created to maintain 
funds for the UNC medical center with principal 
offices located at 880 Airport Road, Chapel Hill, 
North Carolina." 

This language creates an unrestricted bequest for 
use by the medical center when and where the need 
is greatest, or you may specify that your gift be 
used for a particular purpose. 

For further information on bequests, contact 
Jane McNeer at (919) 966-1201, (800) 962-2543, 
orjmcneer@email.unc.edu. 




Medical Alumni 



BUiXETIN 



School of Medidne, Unhnersi^ of North Carolina at Chapel Hill 




rancis Collins, MD 77 

Guides Effort That Is 
Changing Medicine 



Dean's 
Page 

state of the School 2000 

Rcceiitl). in iiiv annual ""stale ol the 
School of Medicine" presentation to lacuitN 
and staff. I described the many w a\ s UNC is 
setliny a new standard of excellence in 
teaching, lesearch and patient care. 

We are wiirking to undergird our educa- 
tional mission with three major thrusts: Fo- 
cusing know ledgeable faculty leadership, 
developing leading-edge facilities and de- 
ploying outstanding program de\elopment. 
We"\e made tremendous strides in each ol 
these areas, and I wanted [o share that infor- 
mation w ith Nciu. our alumni and friends. 

Leadership: I have often referred to 2000 
as ""the year of recruiting chairs ' The 
.School of Medicine recruited eight new lac- 
ully chairs this year. Since I joined the 
schot)! in l*-)97. vve"ve recruited a total of 14 
new chairs, four new center directors and 
two new center co-directors. 

Many of these faculty leaders studied or 
trained at Carolina, and consider their return 
to he a homecoming of sorts. Others were at- 
tractetl by the appeal of living in the Town 
on the Hill and by Cart>lina"s international 
reputation lor high-e|Liality education and 
clinical care. All of them come with 
impressive academic credentials and prmen 
track records of exceptional program 
de\elopment. 

Please join me in welcoming our most re- 
cent new department chairs. The\ are: V\ tas 
Bankaitis. PhD. cell biology and anatomx ; 
Luis Diaz. MI), dermatology; Frank Fongo. 
MD. PhD. Neurology. Terry Magnuson. 
PhD. genetics: Lee McLean, PhD. allied 
health: Travis Meredith. MD. ophthalmolo- 
gy: Marschall Runge. MD. PhD. medicine: 
and .-Xlan Stiles. MD. pediatries. 

The Medical Alumni Biillviin has |nih- 
lished profiles on some of these facult\ 
chairs alreatl\. aiul will continue to intro- 
duce you to others in upcoming issues. 

Facilities: .-\n\one w ho has spent time in 
the School of Medicine's educational or re- 
search buildings knows the amount and 
quality of space lea\es something to be de- 
sired. But. several positive improvements 
are under vva\ . 



First, the Neurcseiences Research Build- 
ing is expected to open this spring. The 
eight-story. .$30-million facility will hi>usc 
the L'NC Neuroscience Center, where re- 
searchers will study issues related to the 
brain, including how the brain develops and 
how it responds to damage. The building 
also will prov ide permanent space for the 
neurobiology curriculum and adtlitional 
space for several new facultv members in 
basic neuroscience. 

Other occupants include the School of 
Medicine's animal-models center and its 
"mousers." researchers who study mouse 
genomics. Research components of the de- 
partments of ophthalmology and neurology 
also vv ill move into the new facility. 

Construction on the Medical Biotnolecu- 
lar Research Building is under way. as well. 
This lOO.OOO-square-foot. $64-million fa- 
cility will house 60 to SO principal inv estiga- 
lors. and prov ide two auditoriums, one 
seating about 500 people, the other .^00. 

Voter enilorsement of the Nov. 7 bond ref- 
erendum means the School of Medicine will 
receive nearlv S.'^O million to finish the 
Medical Biomolecular Research Building. 
The boiuls also will provide another $60 
million to make desperately needed renova- 
tions and improvements to the Medical Sci- 
ence Research Building, the Burnett- 
Womack Building. Beiryhill Hall and other 
facilities. 

Pntjjram development: We have plans 
to grow om genomics, vascular biology, 
bioinlormatics and infectious disease pro- 
grams. Vascular biology will get four new 
faculty positions, while infectious disease 
has alreadv recruited faculty for two new po- 
sitions. 

The Department of Genetics, under the 
direction of Dr. Magnuson. will receive 10 
tenure-track faculty positions from the 
School of .Medicine. Last year, the program 
received S2.6 million over four \ears from 
the How ard Hughes Medical Institute to 
help establish genomics core technologies, 
including a chromosome imaging facility. 
The HHMI money also w ill help recruit four 
junior faculty members by offering start-up 




packages for equipping their laboratories 
and prov iding support for technical person- 
nel and supplies. In addition, there w ill bean 
another 16 facultv positions funded by the 
L'niversity in various other programs across 
the campus. 

In bioinlormatics. four new faculty posi- 
tions have been allocated and I've granted 
"licenses to hunt" to build programs in kej 
areas. Reflective of our effort to meld clini- 
cal expertise with bioinlormatics knowl- 
edge, the School of Medicine was ju"Sl 
awarded a contract by the Cystic Fibrosis 
Foundation Therapeutics. Inc.. an affiliate ol 
the Cv Stic Fibrosis Foundation, to create anc 
maintain the nation's first comprehensivj 
bioinlormatics center for cv stic fibrosis re- 
searchers. 

Recruiting more researchers continues tc 
be one of my piiorities. and the faculty of th( 
School of Medicine have supported me bj 
allowing me to withhold 1 percent of al 
state dollars for the purpose of creating new 
positions. By 2001. this withhold will b< 
worth SI. 6 million — all of which will b< 
used to partiallv support up to 40 new faeul 
t_v positions. 

The School of Medicine is an organiza 
tion full of exciting new initiatives led by 
dedicated and motivated faculty and staff 
who are committed to excellence and who 
have great expectations for tomomnv . 

Future Dean's Page columns will focus 
on other elements relating to the "'State of 
the School of Medicine." Nc.xi: Re-shaping 
the curriculum and what we're doing to 
address other educational issues. 



mn 



L 



i-tu^t 



JctfirxLHiniin.MD 
Dean. ScluKil ofMcdiiinc 



0; 




-— 


.-.-- -- 




' DEC 

HE.KLTH SCi 


T 





Medical Alumni 
Association Officers 

President 

Paul E. Viser. MD '84 
Clinton 

President-Elect 

Thomas J. Koonlz. MD '66 
W'inston-Sdicni 

\ ice President 

Ray M. Ha\ worth. MD "62 
Kno.uille. Tn 

Secretary 

JohiiM. Hcrion. MD"83 

\Vilniini;t(>n 

Treasurer 

WilhamM. Herndon. Jr.. MD'Sl 
Charlotte 



Editorial Staff 

John \\. Stokes 

Vice President. Public Affctirs 

& Xfcirketiiiii 

Debra Pierce 
Editor 

Michele Ble\ ins, Bernadette Giilis. 
Catherine House. Leshe H. Lang. 
Katie .Macdonald. L\nn W'ooten 
Conlrihuli/ii^ Writers 

Dan Crawford (pg. 20) 

Steve Exxum (p<z. ?<) 

Jay Magnum (pg. 11. 14. \5. IX. 24i 

Will Ouens (pg^ 2..^) 

Photo\ir(ipher\ 



llic Miiin iilMiiinni Hiillcliii is published tour times 
annuiillv h> ihefNC-C'hapc-l Hill Mcdic;il Aliinirii 
Asviciatiiin. C'hiipol Hill. .\C 27.^ 14. P(islai;e IS p.ml 
h\ ihc min-protil a^s()l.■lalllln ihrouyh L'.S. Postal 
Pcrmil No. 24. .Address correspondence to the editor. 
Office olMedical Center Public .Mfairs, School ol 
Medicine, CB#7WK). I nixersitv or North Carolina, 
Chapel Hill. NC27,S 14 



Medical Alumni 

BULLETIN 

School of Medicine, University of North CaroHna at Chapel Hill 



Contents 



Features 



With Scientific higenuits and a Little Lucis, L'NC Physicians Help Couples 
Concei\e Babies 2 

Women's and Children's Hospitals Will Be the Newest Additions to the UNC 
Health Care Famih 4 

,Muiiiiii Profile: .Alphabet Soup 

LW'Ciiliini tiiincis Ccllins SeiTes Upthe Huimin Genome 'Recipe' and Sets ilie 

,S7(/.t,'c FcrA Mind-Biii:i;linii Medical Revolution 6 

Health .Al'tairs Bookstore Has A New Home 9 

Dean's Choice Ill 

Family Day 2000 14 

Faculty Profile: Marschall Range, .MD. Chair. Department otMedicine I S 

Scholarship Established In Honor of Harold Roberts. MD 20 

UNC Protessor Endow s National Prize In Neumscienee 2 1 

2000-2001 Loyalty Fund Scholars 26 

Lo\alty Fund Campaign 2S 

Report to Donors 29 



Departments 



Dean's Puge Inside FionlCtner 

News Briefs 12 

Faculty Notes 16 

Research Notes 22 

Developtneni Notes 24 

.Aluinni Notes 25 

Piesidcnl's Letter Inside Back Ciner 

CME/Alumni Calendar Back Co\er 

(hillh Cinii: .MicT 10 lonj; scaisol pivp.ir.iUon Ir.iiK is( 'olliiis. .\1I) 77 ,iiul the icsc.uch 
stall at the NatKinal Human (lenomc Research Itistitiiic alony w ith scientists wnrkiiii: 
together at laboratories around the world cracked the hiuuan body's jicnetic code, an 
astoundin': feat thai promises lochanj;c medicine loiever Photos fnim the,! line 2{KH1 
newsconterence held at the White House ,irc couilcs\ ol ihc N.ilional institutes ol Health. 



With Scientific Ingei 
UNC Physicians Helj 



By Catherine House 

Late one night, Stan 
Beyler, MD arrived at 
the airpoil alter a busi- 
ness trip and boarded 
a shuttle to his ear. It wasn't 
erowded. so Beyler notieed that 
a niuseular man dressed in 
leather and seated at the baek of 
the bus was staring at him. It 
made Beyler uneasy. 

Suddenly the man in leather 
blurted out. "Hey! You're ihi 
man who got my w i K 
pregnant." 

Antieipating trouble, ilu 
other passengers braeed them- 
sehes against their seats, but 
Beyler ealmly replied, "Oh ^''^'<''' ""'' 
sure. I remember you. How are 
you doing?" 

As it happens. Beyler was only doing his 
job. As a seientist at UNC Hospitals 
.Assisted Reproduetive Teehnologies (ART) 
pntgram, Beyler works with t'eilility speeialists 
to help eouples eoneei\ e. 

Despite the \ast number ol unintended 
pregnaneies eaeh year in the United States — 
about three million, aeeording to the Alan 
Guttmaeher Institute — getting pregnant ean 
sometimes be extraordinarily diffieult. As 
many as 10 million Ameriean couples are 
infertile, and some spend years trying to 
conceive, often without success. 

In vitro fertilization (IVF) — commonly 
know n as "test tube" pregnancy — has 
helped many couples achie\e their dream of 
lia\ ing a child. Since m7S, there ha\e been 
moixMhan 30().()()() successful IVFs world- 
u ide. .At UNC Hospitals, about 125 couples 
undergo IVF each year. About 
40 percent become pregnant and some 30 
percent end up with a live biilh. 

While that rate may seem low. Be\ ler. 
clinical assistant professor of obstetrics and 
gynecology and director of the clinical 
androloev and embrvoloi;\ laboratory. 




Ills cliiUlrcii Piiiil (iiul Bcckx. wife Marxhah aiul cut Mil, 



explained that it is similar to "natural" 
conception rates. Even with no fertilitv 
problems and no contraceptive use. only one 
in three reproductive cycles result in successful 
pregnancy. 

Also. Beyler explained. IVF is onl\ 
successful w hen both piirties have functioning 
gametes — that is. eggs or sperm. If a 
woman's egg quality is poor, then an egg 
donor is a possible alternative. Older women, 
for example, may be able to carry a child, but 
their eggs might be "worn out." A woman is 
bom with all the eggs she will ever have — 
about two million — but by the time she 
reaches puberty, there may be only about 
400.000 left. By the time she turns 40. there 
may be \ cry few good qualitv eggs left. 

If a man isn't able to produce spemi. then 
the only option is to use donor sperm. But 
e\ en if a man has a low count. Beyler said, 
pregnancy is possible. Sometimes the spenn 
just needs a little help reaching its destination. 

E\ en when a man has a normal sperm 
count, less than I percent of the spemi present 
in the ejaculate actually make it into the 
woman's uterus, and fewer still make it to 
fertilization site in the fallopian tube. In this 



case, Beyler can use a proce- 
dure called interuterine in- 
semination in which the 
man's spenn is taken directly 
futm his testicles and inject- 
ed into the woman's uterus 
w hen she's ovulating. But 
that doesn't guarantee 
fertilization. 

Michael GO' Rand. MD, 
professor of cell biology and 
anatomy and one of the 
founders of UNC's IVF pro- 
gram, studies sperm-egg in- 
teraction. To understand the 
process, consider the design 
of a human egg. Eaeh egg has 
a shell around it, called a 
zona pellucida, that protects 
the egg, provides a secure 
place for the embryo to grow 
and keeps extra sperm from 
getting in. First, the sperm has to penetrate 
the shell, and then it has to fuse with the egg. 

In each of these steps, certain proteins in 
the spemi are insohed. 

"If a man is infertile, one or more of those 
proteins may be missing or nonfunctional." 
O'Rand said. "We're trying to understand the 
basic biology of each of those steps — 
figure out which proteins are needed for 
w hich step." 

While this work e\entually may help re- 
searchei's restore function to defective sperm 
by adding new proteins. O'Rand siiid "micro- 
manipulation" techniques — recent procedures 
designed to facilitate the fertilization process 
— often b\ pass the protein problem. But if 
doctors somedav could tell w hether sperm is 
defective beforehand, they'd know which 
techniques would work. sa\ ing time and ex- 
pense. 

Beyler said that w hen he started pert'omiing 
IVF in 1987, it was just a matter of finding 
the eggs in fluids sent to his lab and putting 
them into culture. Then the right number of 
w ashed spemi w ere added, and he would let 
nature take its course. But since those "early 



iity and a Little Luck, 
I!ouples Conceive Babies 




Liiiini ct Chi\ Hiillduay with daui^htcis 
Lnuixn and Eiiiilx 

da\s."" a number of techniques ha\e e\()l\ed 
to help int'enile couples. 

The first technique used was partial-zonal 
drillms:. which in\ol\cs (ipening up little 
holes around the egg. The idea is that by 
opening up the shell a little bit. weaker spemi 
can gel in to Icrtili/e the egg. Sub/onal inser- 
tion went a step further: A teu sperm are 
phssically placed in the layer between the 
egg membrane and the shell, in hopes that 
one will penetrate the egg. This procedure 
doesn"t always work, though, because the 
sperm often just end up swimming around in 
the fluid between the shell and the mem- 
brane. 

Fmallv. there's mlrac> loplasniic sperm 
inieclmn ( ICSI). in which the spc-mi is injected 
direcll\ into the inside of the egg. Beslersaid 
It's important to avoid damaging the egg 
nucleus w ith this priK-edure. 

"There are a lew tricks imohetl to make it 
work well." he said, "l Inst kill the sperm 
ph>sicall> h\ breaking iis neck with the 
injection pipet. draw u|i its tail and then 
quickls enter the egg cstoplasm. After that. I 
suck back some egg cstoplasm to make sure 
I'm through the membrane and lo allow ihe 



sperm lo mi\ with the egg cytoplasm. 1 then 
inject the sperm and c\ toplasm mixture back 
into the egg." 

To help improve IVF success. Beyler and 
his colleagues began seeing patients in c> cles 
rather than continuous!). That wa\. he sa\ s, 
they can work w ith several patients at one 
lime, perform IVF for them, step back and 
analyze the results. 

For instance, they're trying to make the 
cultures in test tubes more like fluid in the 
fallopian tube at mid-cycle. For IVF. embry- 
ologists used to use a nonspecific culture 
medium — the same kind used for experi- 
ments such as growing cancer cells. 

"But there were a lot of extraneous nutri- 
ents that weren't vital lo fertilization and 
might even be detrimental to earh iirowth." 
Beyler said. 

During the middle of a woman's cycle, for 
example, there isn't much glucose or phos- 
phate found in the fallopian tubes, but both of 
these nutrients were in the original media. 
Beyler found that eliminating some of the 
glucose and phosphate appeared to improve 
pregnancy rates. 

"It's a lot of trial and error." Bevler said. 
".Sometimes it's a matter of prescribing dif- 
lerent combinations of homione medications 
or tr\ ing a new piece of equipment." 

A tew years ago. there was an unusuallv 
high rate (about .^0 percent) of multiple 
pregnancies. Techniques had improved for 
stimulating egg growth, for getting more 
eggs to lenilize and for better culture condi- 
tions. To compensate. Beyler and his 
colleagues tried waiting three to five davs 
instead of two days to transfer embiyos to the 
woman's uterus. This was. doctors can pick 
out the strongest ones and transfer fewer. 
Bevler said mulliple-pregnancv rates have 
come down lo 2(1 peiceni. mosi ot which are 
twin pregnancies. 

.Another helpful technique is crvopreser- 
valion - lieezing eggs, sperm, or embryos - 
which allows more chances at fertilization 
with frozen sperm, or the transfer of thaw eti 
embrvos to ihe ulerus. Irom one sperm 



biopsy, for instance. Bevler can separate the 
sperm into small quantities and freeze the 
portions he doesn't use. 

"I onlv need a few thousand sperm to w ork 
w ith." Beyler said, "and typically even a 
small count has a few hundred thousand 
around." 

In line case. Bev ler combined IVI- and 
cr\ opreserv ation. A cancer patient decided to 
hav e some of his sperm frozen before under- 
going cancer treatment since chemotherapy 
tends to reduce spenn count. Ftir 1 9 \ ears, his 
sperm were kept in UNC's sperm bank. 
About a year ago. the patient and his wife 
decided they w anted to have children. Be\ ler 
thawed Ihe patient's sperm and performed 
ICSI to lertilize his w ife's eggs. While she 
didn't conceive on the first attempt, the lab 
still has plenty of sperm. 

"The sperm seemed to be line." Bevler 
said. "We think the problem might have been 
a female factor, so if we can tlgure out how to 
get better eggs from the woman, then we can 
tr\ again." D 

I This arricic appcuis in liic I'nil 2(HH) issue 
('/'Endeavors iihi\:(i:inc und is irpiiuiccl with 
permission. ) 




t.rsscr. wife IUiilhii,i i 



Women's and Childrei 
Newest Additions to the 



Construction of the new N.C. 
Women's and Children's hospi- 
tals has been hampered by 
numerous factors, including: 

• A deluge of rain in 1998 that caused a 
4()-day delay; 

• Changes made to the original design as 
well as changes required by the builder, 
and 

• Unexpected glitches, such as the required 
removal of more rock from beneath the 
construction site than was first predicted. 

As soon as construction is complete, work 
begins on the renovation and expansion of 
the lobby in the main hospitals building. That 
reconfiguration will connect an improved 
lobby and expanded outpatient pharmacs 
area with a two-story, glass concourse run- 
ning the breadth of the entire medical center 
complex — allowing patients, visitors 
and stall to easily mcne from one building to 
another. 

To learn more about the new hospitals and 
to see artist's renderings of patient rooms, 
lobby and nurses station as well as construc- 
tion photos, \'isit www.unclwalthcare.org 

Facts about the 
N.C. Children's Hospital 

•The all-pri\ate patient rooms are 
designed to feel as much like "home" as 
possible. They feature private bath 
rooms with tubs and showers; laminated 
walls so children can display artwork, get- 
well cards and photographs; and conveil- 
ible sofas to accommodate relatives 
spending the night. 

• UNC offers the state's only accredited 
Hospital School for children in K-12 with 
teachers and a full-time principal to help 
children keep up with their classroom 
studies during their hospital stays. 



' Pediatric care at UNC was ranked 22nd 
nationally by U.S. News & World Report 
magazine in its annual "Best Hospitals" 
ranking. 

' The N.C. Children's Hospital will offer 
"one stop health care" for children and 
their families: all pediatric clinics will be 
housed under the same roof, and feature 
kid-specific and kid-friendly operating 
and pnicetlure rooms. 

' The hospital will offer interactive enter- 
tainment for children. One will be an 
atrium with a mbber-foam tloor designed 
to look and feel like an outdoor park com- 
plete with flowing "brook" and a bridge 
to cross it. Teen-age patients will enjoy 
their own private lounge stocked \\ ilh 
music and video games. (It is so "cool" 
that parents must be accompanied by 
theii' teens to access it.) The lobby will 
feature a dazzling, two-storied continu- 
ous motion sculpture. 

' Annually, more than 72,000 children 
from all 100 North Carolina counties 
come to N.C. Children's Hospital for in- 
patient and outpatient treatment. UNC 
offers a full range of pediatric specialty 
and subspecialty care, including compre- 
hensive intensixe care, a Level-I Trauma 
Center and a state-of-the-art bum center. 
UNC is one of just two hospitals in the 
Southeast to perform living-related li\er 
liansplants. 

' Nationally and internationally renowned 
experts in the fields of cystic fibrosis, on- 
ciilogy, hemophilia, sickle-cell disease, 
infectious disease, genetics, neonatology, 
child abuse, endocrinology, bron- 
choscopy and congenital heart disease 
work at UNC Hospitals. Our facult\ 



consult with community doctors through- 
out the state 24 hours a day. 

The Newborn Critical Care Center cares 
for more than 750 babies a year from all 
over the Southeast. About one-third of 
the babies are transported here by pedi- 
atric-trained specialists with the UNC Air 
and Ground Transport Service. 

Facts about the 
N.C. Women's Hospital 

The N.C. Women's Hospital was 
designed to offer patients and their fami- 
lies as much comfort and privacy possi- 
ble. All patient rooms are private and 
feature a conversation area, private bath 
w ith tub and shower, and a convertible 
sofa to accommodate relatives spending 
ihcnighl. 

The new facility is conveniently located 
and offers a comprehensive, integrated 
approach to women's health. Women 
from throughout North Carolina will re- 
cei\e care in the areas of obstetrics and 
gynecology, cardiology, geriatrics, can- 
cer, nutrition, alternative medicine, and 
beha\ ioral and mental health. 

Housing all clinics under one roof 
enhances the accessibility of care and 
offers a wami. inviting atmosphere to pa- 
tients and their loved ones 

A Women's Resource Center is planned 
for the lobby. It will include an interac- 
tive library with literature and journals; a 
nurse educator to talk w ith women and 
help them find useful health information: 
and expanded patient education programs 
and seminars currently offered through 
the Women's Wellness Network. 



5 Hospitals Will Be the 
JNC Health Care Family 




Thr \.C. Chihlrvns H<.s,nu,l a,ul ,hc \.C. \\nnwu\ l/,n,,„al. Dcluainm cvnus ,nr planncj (or Scpl. S. 20111 



• The Irianiile's onls hospnal -havcd. 
nurse-midwil'cn, program oporaics liom 
N.C. Women's Hospital. MalL'niit\ care 
lor all patients — inekidini: lahor. deln - 
or\. recover, and posiparliim care — \>, ill 
he delivered in one room. There also \m1I 
he plenty of space torhahs lo sta\ uith 
mom. Rooms located in the maternil\ 
u int; alsci include rocking chairs. 

• The N.C. Women's Hospital uill he 
capped u ith a scilarium complete u ilh 



touniam and sk> light lo olTer a pleasant. women's and children's medical care 

warm and nurturing en\ironmeni lo pa- w ill he li>caied on the second lloor 

tients and their lamihes. 

•.An outpatient phaiinac), chapel, 
• Board-ccrtilieil. nationalh renowned and calcleria are locateil iii the new 

physicians oiler care in the areas ol ma- lacihtv, 

lernal-lelal meilicine. uiogynecolog), in (Sec irhiu,! slnr\ on pane / U 
lertiliis. pen- and post menopause, can- 
cer, radiology /mammogra|ih\ and anes- 
thesioloiiv 



Si\ 



-■rating rooms deilicatcd t( 



Alunini Profile 



Alphabet Soup 

UNC alum Francis Collins serves up the human genome 'recipe 
and sets the stage for a mind-boggling medical revolution 



By Lynn Wooten 

Last June. Francis S. Collins. 
MD. PhD. sUhk! hi ihc Blue 
Room of the While House, 
looked around and found 
himself in the company of ambas- 
sadors, senators and other go\emmeiil 
heavyweights. Soon, even the president 
of the United States would he joining 
him. After 10 long years of preparation 
and work, this was. at last, the big da\ 
— the announcement to the world that 
Collins, his research staff at the Nation- 
al Hiuiian Genome Research Institute, 
and scientists working together at labo- 
ratories around the world had cracked 
the hiuiian body's genetic code, an as- 
tounding feat that promises to change 
medicine forexer 

Yet in a few moments, Collins, w ith 
President Clinton at his side, would 
enter the East Room, step up to a podi- 
um, and in front of a roomful of re- 
porters mask an internal conflict of 
devastating irony. Just four days earlier, 
his sister-in law had died of one of the 
most dreaded and common diseases to 
strike women. Ha\ ing spent the previ- 
ous day at her funeral and comforting 
his grie\ ing brother, Collins was stRick 
by the unique hand fate had dealt him. 

"The juxtaposition here of an exhilarating 
moment in science, with such promise for 
the future of medicine, and the reality of how 
this had come much too late to help this 
wonderful woman, had me a bit confused." 
Collins said. "It v\asabil Jannng." 
It's no wonder. 

The decoding of the human genome — 
the molecular makeup of a himian being — 
is hailed as the prerequisite leap toward un- 
locking the secrets of disease, illness, bnlh 
defects and other health issues that have long 
st\ mied researchers and physicians. In other 
words, knowledge that might save millions 
of women like his sister-in-law in the future. 

As Bill Clinton entered the Blue Room 
and approached him. Collins temporarih 
shook off these family concerns. 
6 




Francis Collins. MD '77 



"I thought, "This is really going to happen. 
This is a pretty big deal.' Pretty soon, we are 
w alking into the East Room while the band is 
pla\ ing 'Hail to the Chief.' Tliat's lui experience. 

"When I was a medical student and house 
officer in Chapel Hill, the notion that my path 
would somehow lead to that kind of an e\ent 
would have been completely unthinkable." 



COLLINS' YEARS AT UNC almost 
didn't happen. 

"I was on the launching pad to go to that 
other university called Duke w hen the More- 
head Foundation expressed an interest in 
interviewing me for one of three Morehead 
fellowships." he remembered. "So I came to 
Chapel Hill w ith m\ heart in m\ mouth in 
early Februar\ of 197.^ to be interviewed 



w ith five others. Christopher Fordham 
w as the chairman of the Morehead 
medical fellowship inter\ iew commit- 
tee. I really fell in lo\e w ith the tow n 
and the uni\'ersity that weekend." 
Within days, he was accepted. 
The decision to enter UNC's School 
of Medicine was not his first career 
change. Always interested in science, 
the Virginia native had first gone to 
Yale University to obtain a doctorate in 
physical chemistry. 

"I thought that's what I wanted to do. 
but I disco\ ered there were some pretty 
exciting things gomg on in biology and 
genetics." although not advanced 
enough yet for human application. "So 
I went to medical school in quite a bit of 
confusion abt)ut w here my ow n path 
would lead." 

Would he focus on science and re- 
search or. as he phrased it. on "simply 
being a good doctor?" 

Collins found his answer. A brief 
course in December 1973 by Henry 
Neil Kirkman Jr.. MD, looked at the ba- 
sics of human genetics. Kirkman pre- 
sented a patient w ith sickle cell anemia 
and illustrated in a pow erful w ay how a 
simple misspelling in the DNA code 
could have profound consequences for 
the health of that indi\ idual. 

"\M I was captisated," Collins said. "This 
brought together my interests in science and 
a principle-based approach to understanding 
problems with a direct application to human 
health. 1 knew at the end of those two w eeks 
that w as w hat I w anted to do — I w anted to 
he a physician who used the tools of genetics 
to trv to understand disease better." 



GRADUATING FROM the School of 
Medicine in 1977. Collins undertook his 
residency and a chief residency at UNC. 

"I have very warin feelings for him. He 
was always a hard-working but joyous 
person to be around." said classmate David 
C. Henke, MD, assistant professor of medicine 
at UNC. "He walked around with a cup of 




Collins iiHikes reimirks at June 2000 news conference held in the White House. 



ct)tYee all the time because I don"t think he 
e\er slept. And he was a stickler for getting 
things right. e\en from the teachers. If 
an instructor ga\e out what Francis knew was 
incorrect information, he would ne\er let it 
slide." 

Collins. 50. said he had sp)ecial mentors at 
L'NC. "The one that stands out most for me 
was the late John Parker, a consummate 
ph\ sician ... the kind e\er\ one would hope to 
belike." 

Recalling the first week he was in charge 
of patients during his residencs. Collins said 
Parker, a Kenan professor of medicine, w ent 
behind him to make sure he had not ""missed 
an\ thing." Parker's manner, though, was not 
threatening; rather, it was inspiring. Collins 
said. ""I wanted to ha\e that same kind of 
breadth and thoroughness."" 

Collins returned to 'Sale for a fellowship in 
human genetics, w here he worked on methods 
of crossing large stretches of DN.A to idcntif\ 
disease genes. Joining the facult> of the 
L'ni\ersiiy of .Michigan in 1984. he continued 
to develop these ideas, w hich he called "posi- 
tional cloning.""The concept developed into a 
powerful component of modern molecular 



genetics, as it alknvs the identification ot 
disease genes for almost any condition w ith- 
out knowing beforehand what the functional 
abnomialitv might be. 

Using this strategv. Collins and Canadian 
researchers identified the gene for cystic 
llbrosis in 1989. followed by the discoveries 
of the genes fiir neurofibromatosis and 
Huntington's disease. 

In 199.^. Collins became director of what 
is now known as the National Human 
Genome Research Institute, the public 
organization that is part of the National 
Institutes of Health. The NHGRI was 
charged with the task of mapping and 
sequencing the human genetic code, as well 
as identifying and recommending solutions 
to ethical, legal and social issues that could 
result from the human genetic code. The task 
includes sequencing all .VI billion biochemi- 
cal '"letters"" of human DNA. the coded in- 
structions — the '"recipe" — for a 
functioning human. Using this instruction 
book, scientists can begin to ferret out in a 
molecular w av the secrets of human health 
and disease. With the working draft of the 
genome sequence completed and a finished 



version — which will be as complete as hu- 
mans and computers can nuike it — expected 
before 2003. experts predict monumental ad- 
vancements into diagnosing and treating 
everv thing from cancer to .•\l/heimer"s dis- 
ease. 



"THE ACCOMPLISHMENT." Collins 
said, '"is clearly a milestone of the highest 
order."" 

Don"t think Collins is patting himself on 
the back, though. Eschew ing even the notion 
that he might w in the cov eted Nobel Prize for 
his work, he seems quite uncomfortable w ith 
the praise lauded on him. He quickK credits 
"a long list of heriiic figures in science"" for 
their contributions. ""This milestone was their 
work." 

Others recognize Collins' imprint on the 
project. 

"He is clearlv at the lop of his profession."" 
Henke said. '"He is right there in what I'm 
sure will be the seminal work in medicine for 
this century. I'm very impressed w iih his ca- 
reer and work." 

But striv ing tor the same goal w as J. Craig 
Venter. PhD. president and chiel scienlific 
officer of Celera Genomics, a private organi- 
zation running an independent genome- 
sequencing project. Some observers consid- 
ered Celera to be the Collins group's chief 
rival, but w hile the media trumpeted a "feud" 
between the men and their organizations. 
Collins saw things differently. The percep- 
tion of a nasty, rancorous race to the genomic 
finish line, he said, has been overstated 
considerablv. But he conceded that such talk 
probably inspired his scienlisis and "siiired 
thepol." 

"1 think competition is almost always a 
good thing." Collins added. 

.And contrary to media reports that Clinton 
forced Collins and Venter to work together in 
jointly announcing the status of their 
research. '"I had no pressures coming dow n 
from the White House to take a particular 
action." Collins said. "The media got that 
wrong." 

('onliiiKfil (in I'liiie S 

7 



Alphabet Soup 

Ciiiiiiiuicil Jioiii /'((,1,'c 7 

With the first draft of the 
genome map in place, the world 
now can expect a new 
competition, one w ith staggering 
fmancial stakes. Amied u ith the 
human genetic code, phamiaceu- 
lical companies alread) are rac- 
ing to develop drugs and other 
therapies geared to an indi\ id- 
Lial's own genetic makeup. Such 
personalized treatments should 
dramatically improve a patient's 
care and response. 

'"E\er\ phannaceutical compa- 
ny is counting on this." Collins 
said. "You w ill see a transfomia- 
tion in how medicine is prac- 
ticed." 

While new medical and scien- 
tific advancements will occur 
steadily, people shouldn't expect 
a cure for cancer or diabetes next 
year, he added Although the 
genome's letters have been prop- 
erly sequenced, scientists don't 
yet know what their "Book of 
Life" means - they can't read it 
yet. And many experts believe 
that understanding the genome's language 
will be a much more difficult task. 

■"The thing that people w ill notice in tenns 
of their ovv n medical care ov er the next fiv e to 
seven years will be the increasing availability 
of DNA tests that will allow people to deter- 
mine their indiv idual risk of future illness." 
Collins pointed out. "In particular, know ing 
you are at high risk and allow ing you to do 
something about that risk. For instance, 
something like colon cancer- those at high 
risk taking advantage of colonoscopy in 
order to pick out those tumors w hile they are 
small and easilv removed." 

.^Xnd therein lies an ethical debate over 
genome research; Should patients be told 
they likely will be stricken with an illness or 
disease later in life, particularly if there is 
little medical help available at the time? 

"Indiv iduals ought lo have the chance to 
make up their minds of w helher thev w ant 




Collin 
gniihlctai 



ith daughters Margaret, left. Elizabeth, right. 
tghter Ahby. 



that information or not." Collins said. 
"Nobody should force that information on 
people w ithout them deciding they want to 
know that. I think many people w ill not want 
to know about risks for which there is no 
intervention available. I would say. "No. 
thank vou." " 



CONTROVERSIES AROUND the 

potential contlicts between religious and 
scientific v lews of humanity intrigue 
Collins, a self-described "serious" Christian. 

"I have not found those conflicts at all," 
he said, suggesting that such controversies 
lack factual understanding about the 
genome and the research process. Finger 
pointing between the w odds of science and 
religion "points out to me how big an infor- 
mation gap reallv exists." he said. 

But that debate mav be left to others once 



Collins" work is finished in a 
couple of years. What's next for 
his career? 

""That's a very good question, 
and I have absolutely no idea." 
he admitted. ""I don"t 
intend to retire from the federal 
government. I feel I have another 
career or two in me. but I don't 
know what they iu"e yet. I'm tov- 
ing with a bunch of options, but 
am in some confusion over 
which one makes sense. It will 
be very hard to llnd something to 
do after this that has the same re- 
markable intensity and impact." 

Meanwhile. Collins and his 
wife. Diane Baker, a faculty 
member at the University of 
Michigan, continue a commut- 
ing marriage, w hich he called ""a 
bit of a challenge, but we've fig- 
ured out how to handle this pret- 
ty effectively." 

Collins also spends time rid- 
ing motorcycles and playing the 
guitar, including gigs with his 
own band. He enjoys v isiting his 
two daughters: Elizabeth, a medical social 
worker in Ann Arbor. Mich., and Margaret, 
who recently gave Collins his first grand- 
child, a girl named Abbv. 

Margaret Collins Hill. MD. is a 1996 
graduate of the UNC School of Medicine, 
where she also undertook her residency in 
internal medicine and is now a fellow in 
nephrology. Collins is thnlled that .Margaret 
is in Chapel Hill and at his alma mater. 

""I can't think of a better place w here 
I'd like a child of mine to spend her time." 
he said. □ 



Health Affairs Bookstore 
Has A New Home 



By Michele Blevins 

It you haven't visited the L'NC 
Health AtTairs B(H)kstore re- 
cent!}.. _\ou ina\ mn recogni/e 
the place. The hooivstore has 
relocated and expanded just a bit 

— it now occupies tour floors of a 
brand-new fi\e-siory building. 

h"s quite a change from its pre- 
\ ious location — on the first floor 
of the Brinkhous-Bullitt Building 

— \v here the sales floor w as only 
600 square feet. In its new home, 
the bookstore has a sales area of 
7.000 square teet. more than 10 
times its original size. 

.All that additional space has en- 
abled the biHikstore to enhance the 
variety of features and services it 
offers the UNC health affairs community. 

The depth of inventory on books, for 
example, has signiflcantly increased. Selec- 
tions now include popular book titles, com- 
puter manuals, cookbooks and children's 
books, all in addition to the ever-present 
classroom texts, studv guides and medical 
reference titles for health affairs students. 

But customers will And much more than 
just hooks when thev visit the store 
Computer software and supplies and a vari- 
etv of medical equipment and accessories 
are just some ot the new items the bookstore 
carries. 

A full line of medical apparel is available 
for students and health professionals alike, 
including lab coats, nursing unitomis. scrubs 
and clogs. 

In addition, clothing and gitt items aie 
available that represent all ot the L'NC health 
affairs schools, including the .Allied Health 
Sciences programs. Fhe store's selection ot 
UNC collegiate clothing and gifts has 
increased as well. 

And for anyone who wants to uiiw iiul 
with a cup of coffee or u snack, there's Cate 
Caducous — the store's coffee shop — locat- 
ed on the third floor ot the buildin::. which is 




The ncu Hcalili Affairs Bookstore. 



acluallv the store's main entrance level. In 
addition to a seating area w iih laptop connec- 
tions inside the cafe, there also are outdoor 
seating areas on the second and third floors 
of the building. 

The second floor includes a conlerence 
room that can hold up to .^0 people and is 



available tor use bv health alTairs tacul- 
ty. staff and siudents. .Also located on 
the second floor is a L'NC Printing 
Copy Center, w hich relocated trom its 
former home in the MacNider Build- 
ing. 

The store is well-equipped to handle 
the rush of students buying textbooks in 
the first weeks of classes each semester. 
There are six cash registers located 
throughout the store to reduce students' 
waiting time during peak book-buving 
season. 

Like other L'NC Student Stores, the 
Health Aflairs Bookstore is a non-profit 
operation that doesn't receive state 
lunding. The store's profits go toward 
non-athletic scholarships for L'NC stu- 
dents. 

The Health Affairs Bookstore is 
located on Medical Drive, behind 
Carrington Hall (School of Nursing) 
and adjacent to Fordham Hall. Hours of 
operation ;u"e Mondays through Fridays 
from 7;.^() a.m. - 6 p.m. and Saturdays 
from 1 a.m. - 2 p.m. D 




A peck in\ulc llic first floor 



Dean's Choice 



By Leslie H. Lang 

How does life work? How does a 
lour-letter alphabet spell out 
instructions for all species on 
earth'.' How does the union of a 
single egg and sperm become a baby of five 
trillion cells? What can the study of molecular 
mechanisms tell us about disease' 

In a sprawling and bustling Fordhain Hall 
laboratory. WUliam F. Marzluff. PhD. 
professor of biochemistry and biophysics, 
the School of Medicine's executive associate 
dean for research, and director of the pro- 
gram in molecular biology and biotechnology 
seeks answers in this arena of big questions 
by focusing small, very small. 

He and his graduate students and postdoc- 
toral researchers study the regulation of gene 
activity; namely, the system of biochemical 
switches that turn genes on and off during the 
mammalian cell cycle and during early 
development in frogs and sea urchins. 

Sometimes the work takes Marzluff to the 
edge of life's very beginnings, each 
e.\]:>eriment moving a .step closer to unraveling 
the biochemical mystery of embryogenesis. 
the process by which an egg transforms into 
an embryo. 

At the heart of this research is a unique 
cellular protein that Marzluff "s UNC labora- 
tory discovered and cloned in 1996. This 
"stem-loop binding protein." v\ hich latches 
onto the looped tail of histone messenger 
RNA. signals the synthesis of histone 
proteins crucial to cell functioning during 
embryogenesis and throughout the organism's 
life. In fact, about half of the nucleoprotein 
complex known as DNA are histone proteins. 

But SLBP does more than simply hitch a 
ride on a loop of nucleotides. It also doggedly 
peifonns a string of important duties after it 
takes the mRNA into a specific region of the 
nucleus. It interacts with other proteins to 
make sure the mRNA is properly processed 
into its tlnal form. And then after helping get 
it out to the cytoplasm, the cell's factory 
tloor. SLBP remains bound to the mRNA. 
making sure that its instnictions are properly 
translated. 

From w hat is known about it so far. that's 
pretty impressive for a compact protein. 
10 



Indeed, according to the latest findings, it 
may be the fundamental regulator of all the 
histone genes which are essential for 
chromosome replication. 

In some characteristic ways. Marzluff 's 
protein serves as metaphor for the man. 
Here's what David Lee, PhD. chair of 
biochemistry and biophysics, says about his 
colleague. 

"I view Bill Marzluff as one of our best 
assets, and I know that view is shared by a 
number of major scientific leaders who are 
here largely because of Bill's recruitment 
efforts. No one brings more positive and 
creative energy, as well as sheer stubbornness, 
to promoting basic science at Carolina. Bill 
has an almost unique ability to work w ith 
biomedical scientists of e\ery persuasion, 
from biologists to biophysicists. and is 
implicitly trusted by the entire community. 1 
am particularly proud to ha\e served on the 
search committee that recruited Bill to 
UNC." 

Science faculty both in and out of the 
School of Medicine sing similar praise for 
Marzluff. The university is widely regarded 
for its interdisciplinan' biomedical research, 
which he tirelessly nurtures and promotes. 

"One great attraction to this university is 
the really top quality undergraduate school in 
close proximity to some of the best science in 
the world. There are not too many places that 
have this combination physically close to 
each other w here they actually do interact," 
Marzluff obsenes. 

And it is to this active research nucleus 
that Marzluff strives to shepherd new faculty. 
"Part of the job that appeals to me is the 
opportunity to recrtiit young faculty and help 
them develop. Chapel Hill is a wonderful 
place to recmit to because of the living condi- 
tions and the collegiality. That's one reason 
that we're recruiting extremely competitively." 

One might be drawn to conjure an image 
of this UNC scientist-administrator complete 
with rep tie. Tar Heel megaphone and lab 
coat of Carolina blue. Instead, how ever, think 
khakis, tennis shirt and sneakers. That is. 
think grad student, v intage early 1970s. Still, 
for those special events and conferences, a 
navy blazer, proper shirt and tie hang behind 
office door. 



Actually, the student image fits appropri- 
ately, sartorially and professionally. His is a 
fast-paced research field vv ith rapidly changing 
technology. And, as Da\ id Lee points out. 
the growing emphasis on interdisciplinary 
approaches to human disease dictate that 
biomedical scientists "be fast on their feet — 
proficient at self-education and able to 
integrate infonnation across a wide spectrum 
of fields." 

Bill Marzluff readily admits that he has 
gone back to school, as it were, .several times 
during his career. 

At Hanard in the mid-1960s (BS, Chem- 
istry. '67). his interest in biochemistry devel- 
oped at a time when an undergraduate major 
in that field did not exist. ( Marzluff 's father 
was a research chemist for American 
Cyanamid.) Biology had not become very 
molecular. Cell biology was microscopy, in- 
cluding much electron microscopy. The ge- 
netic code, the secret words of DNA. 
remained largely unplumbed. 

Marzluff earned a PhD in biochemisti"y at 
Duke, followed by postdoctoral research at 
Johns Hopkins where he worked on gene 
regulation in mammalian cells. 

"In temis of making some particular RNA 
molecules, we were trying to basically repro- 
duce in a test tube some of the reactions that 
went on in the cells. You see. you couldn't 
clone a gene, a piece of DNA. or grow a piece 
of DNA before 1975 or 1976. With the 
advent of cloning, you had to stop everything 
and re-train yourself 

"All the experiments we did before were 
on whole cells. Now we could take an indi- 
vidual isolated gene and just study that. So 
basically you had to stop and re-train. This 
meant learning all the new technologies, 
buying the stuff and figuring out how to 
make it work. So in our area the real excite- 
ment didn't come until shortly after we 
finished our postdocs. 

"Now with completion of the Human 
Genome Project, we have to change the way 
we approach scientific problems again." 

.Marzluff joined the chemistry faculty at 
Florida State University in 1974. During 17 
years in Tallahassee, he nurtured and sus- 
tained a strong undergraduate biochemistry 
program. He came to UNC in 1991, and 




MarzhitJ ui luuue in the research lab. 

e\er\ year at least one student from Florida 
State joins UNC's graduate biochemistry 
program. 

"One of the reasons I went into this busi- 
ness was the opportunity to teach.'" Mar/lutY 
says. "At Florida State, the a\erage annual 
teaching load in the chemistry department 
wa.s9()to I (K) lectures. Here I teach one-third 
of a first-\ear graduate course and a molecu- 
lar biolog) section to medical students. So I 
still do a fair amount of teaching. ' 

Add to that the mentoring of graduate 
students and postdoctoral research staff; 
meeting grant proposal deadlines for his 
lab's research funds: preparing and submit- 
ting articles for journal publication: confer- 
ence planning: fund-raising on and off 
campus on behalf of basic sciences, including 
buildmg construction, grants procurement 
and facult\ recruitment: organizing and 
attending planning conferences: and meeting 
myriad other administrati\e responsibilities. 

"He's the most effective and unusual 
research dean l'\e e\er known." says Jeflre\ 
I.. Houpl. M. dean of the School of 
.Medicine. 



"B> mutual agreement, he has no office in 
our administrative area, he can work on it as 
much or little as he wants — I keep no track 
of his time. But he gets agreement on diffi- 
cult issues like space, cost sharing, and puts 
people together more effectively than an\ one 
I'nc seen. His success is that he's not \ iewed 
as an administrator. I always wanted a 
research dean in this mold and finall\ got it 
uithBill." 

In his ow n deanship, NUuyluff seems allergic 
to limelight. He prefers that it shine on his 
UNC basic science colleagues and their 
accomplishments in recent years. 

"Some great things ha\e been achie\cd 
here, he says. " Creation of the cystic fibri>sis 
model mouse by Richard Boucher. Be\erly 
Koller. and Oliver Smithies. This accom- 
plishment helped increase our understanding 
ol the disease and gain neu insights into its 
treatment. 

".Michael Knowles. Richard Boucher and 
others have followed this by studying neu 
drugs, the P2Y2 receptor agonists, to treat 
lung disease in patients w ith c\ stic fibrosis. 

"We had the discoxerv by A/i/ Sancar's 



lab that cr\ ptochrome. the no\el pigment 
found \\ ithin the e\ e. skin and part of the 
brain, controls circadian rhythm, the body's 
internal clock. This discovery could lead to 
more effecti\ e therapies for depression and 
greater safety during shift u ork at night. 

".■\nother accomplishment was the 
cloning of the molecule I-kappa-B and its 
role in regulating cancer cell growth and 
death." Marzluff continues. "This research 
by W Baldw in is w idel> recognized for pro- 
\ iding an understanding of how cancer de- 
\ clops and ma\ lead to new methods of 
iieatment and prevention. 

"■■Xnd just last year Jack Griffith discov- 
ered the structure of telomeres, the ends of 
chromosomes. This discovery that chromo- 
somes end in loops should prov ide a whole 
new way of thinking about basic molecular 
mechanisms related to cancer and to the 
control of aging in cells. 

"I've watched Jude Samulski and his 
colleagues dev elop the best v ectt)r system for 
gene therapv — adeno-associated v inis. 

"Then there's last December's discoverv 
bv Clvde Hutchison and his colleague at 
TIGR (The Institute for Genomics Research) 
of the smallest number of genes needed for 
an organism's surv ival. This research marks 
a significant step toward creating minimal, 
tailor-made life forms that can be further 
altered for such purposes as making biologi- 
cally active agents for treating illness." 

The research dean also points to the 
appointment last year of biochemisirv and 
biophysics professor Terrv Van Dv ke. PhD. 
to direct the Mutant Mouse Regional 
Resource at UNC. With a S3..'i million grant 
over five vears. this is one of only two NIH- 
sponsored sites nationally that will facilitate 
more widespread use of mouse models in 
basic and translational research throughout 
the U.S. Such models have revolutionized 
the abilitv to probe mammalian biology and 
disease and have become a valuable 
resource. 

Marzluff is proiul that ihc school's 
research reputation and collegial interdisci- 
plinai") atmosphere make it very competitive 
in tacultv recruitment. Some highlv sought- 
after indiv iduals were recentlv tapped to 
direct new research centers. Recently 
appointed are William Snider. MD. head of 
the Neuroscience Research Center and Terrv 
Magnuson. PhD. Sarah Graham Kenan Pro- 
fessor and Chair of the new deparimeni of 
genetics. Magnuson also will direct UNC's 
Genomics Center, cunently under fomiation. 
"This is an exciting time to be involved in 
biomeilical research."" savs Marzluff. "And 
il"s pailicularlv exciting lo be doing it in the 
cnm|\inv (il some ol ilic worUI's besi."' D 



II 



News 
Briefs 



UNC Specialty Women's 
Center uses high-tech 
uhrasound equipment 

Doctors and sonogruphers at UNC 
Specialty Women's Center in Raleigh now 
can perform more detailed examinations of 
Linbom babies by using the latest in high-tech 
ultrasound equipment. 

The new equipment, know n as the HDI- 
3()()(). is a high-definition imaging ultra- 
sound. The technique offers doctors and 
expectant parents such a precise image of the 
fetus that it can detect abnormalities like 
spina bifida, a defect of the central ner\ous 
system that occurs when the neural tube, 
which forms the spinal cord and brain, does 
not de\elop properly. 

Denise Johnson, an ultrasonographer at 
the center, has used the HD1-5(MK) ultrasound 
since Ma_\ and considers it an indispensable 
tool for detecting certain birth defects. 

"It's brand new with all the bells and 
whistles."" said Johnson. "It helps us study 
high-risk obstetrical cases."" 

The HD1-5(XH) ultrasound used at the center 
offers a closer look at congenital heart prob- 
lems, kidney defects and gastrointestinal 
abnonnalities. 

Obstetricians and gynecologists through- 
out the Triangle refer their patients to the 
center for prenatal diagnoses, and some 
patients ha\c tra\eled from as far away as 
Wilmington for the ultrasound. 

"We hope to attract more patients from 
areas that do not cunently offer this type of 
ultrasound, but who could benefit from our 
expertise in maternal and fetal medicine.'" 
Johnson said. 

Wellpath Select, Inc. and UNC 
Health Care Sign Provider 
Network Agreements 

WellPath Select. Inc.. an HMO formedy 
owned by Duke Health Systems, and UNC 
Health Care ha\ e signed agreements that will 
allow WellPath to provide its members 
access to the health care provided by UNC 
Hospitals and UNC Physicians & Associ- 
ates, The contracts include continuing: Well- 
12 



UNC Health Care unveils new lifesaving helicopter 




Loiik. up in the sk_\ 1 It's a bird. it"s a 
plane ... no ... it"s the new Tar Heel One. 
UNC Health Care"s new. state-of-the-art. 
Iitesa\ ing helicopter. Part of the UNC Air 
and Ground Transportation fleet, the 
chitpper w ill offer patients in medical cri- 
sis a faster and safer trip to the hospital. 

"The biggest difference is the technol- 
ogy."' said pilot Shep Kaylor. The aircraft, 
an ECI.^5-T1 manufactured by Euro- 
copter, replaces a helicopter made in 
the I98()s but which featured I97()s 
equipment. 

The new Tar Heel One can transport a 
pilot, three medical personnel and one 
patient and can tly well over 400 nautical 
miles. Kaylor said — far surpassing the 
250-mile range of the previous chopper. 



More fuel efficient, lighter and better 
constructed, the new Tar Heel One is also 
"more en\ ironmentalK friendly." Kaylor 
added. "It bums fuel more cleanly." 

The main benefit for patients is the 
helicopter's speed -e\ en shaving 10 min- 
utes off a night can pro\e crucial for a pa- 
tient in critical condition, said nurse 
Wend\ Rash, a member of the llight team. 

"We will still di> the same type of care 
and procedures, but it will help us out be- 
cause it is faster." she said. "It also has im- 
pro\ed lighting inside for better night 
\ision." 

Striking in appearance, the helicopter 
sports bold Carolina blue and white 
stripes, a large painted Tar Heel on its 
belh and the new UNC Health Care logo. 



Path's long-standing and successful relation- 
ship w ith Rex Hospital and its priman ph\ si- 
cians. Rex Healthcare in Raleigh is part of 
the UNC Health Care System. 

With the contracts effecti\e September I . 
2( K K ). Wei I Path enhances its already substimtial 
pro\ ider network b_\ more than 64 1 specialists 
and 105 primary care ph\sicians who are 
part of UNC's facultv and community prac- 
tices. The contracts include the full scope of 
ser\ ices pro\ ided b\ UNC Health Care, 
including all its hospitals, physicians and 
other health care services, such as home 
health and hospice. Both LWC and WellPath 
are committed to continuing to build upon 
their strong relationship for the greater benefit 



of WellPath members and communities 
served by WellPath and UNC. 

"We belie\e our track record as a leading 
health care system enables us to bring great 
\alue to WellPath members." said Eric Mun- 
son. President and Chief Executi\ e Officer of 
UNC Hospitals. "Our experience in the mar- 
ketplace, our excellent health care ser\ices 
and our positive association w ith many of the 
area's employers have enhanced the health 
and well-being of the people in this region. 
And we belie\e w ith this new relationship 
WellPath members will have more choice 
through our extensive network of physicians 
and hospitals." 



UNC wins contract to create 
the first Cystic Fibrosis 
National Bioinfomiatics Center 

The L'ni\er^it\ of North Carolina at 
Chapel Hill School of Medicine has been 
awarded a contract b\ the C\ stic Fibrosis 
Foundation Therapeutics Inc.. an affiliate of 
the C\ Stic Fibrosis Foundation, to create and 
maintain the nation's first comprehensi\e 
bioinforniatics center for c>stic fibrosis 
researchers. 

The new contract establishes the C>stic 
Fibrosis National Bioinforniatics Center in 
cooperation \\ ith Infomia.x Inc. The contract 
is worth S45().()(KJ over t\\ o years. 

As the amount of infonnation about c\ stic 
fibrosis continues to grow, scientists are 
challenged to carr\ out research that turns 
this information into neu therapeutics as 
rapidl\ and efficienth as possible. While 
there are man) labiiraliiries around the coun- 
try stud_\ ing csstic fibrosis, scientists still 
lack a commtin "language" \\ ith w hicli lo 
exchange know ledge and infonnation. 

■"CF researchers at most universities 
usually rely on the tools at their university, 
meaning that scientists lu'e most often work- 
ing independently of each other." said Da\id 
Fenstermacher. director of scientific comput- 
ing. "One reason for this is that 
researchers use different fonnats for storing 
data, making it difficult to go to another 
cystic fibrosis data site and learn from 
infonnation stored there. " 

The Cystic Fibrosis National Bioinloi- 
matics Center will allow the foundation to 
use UNC as a central repository for data 
derived from gene expression studies. When 
one group uncovers important data, another 
participating group can use that information 
for its subsequent expenments. 

For more than two decades. INC has 
been nationallv and internationallv recog- 
nized for its premier CF Foundation research 
center and accredited care center 

The Cystic Fibrosis Foundation will 
provide researchers access to Gcnomax. a 
database and data-mining tool produced by 
Infomiax Inc. to be housed at UN'C where it 
can be accessed via the Internet. Technical 



and application assistance will he available 
i^ound the clock. 

"This initiativ e betw een academia. industn. 
and a non-profit, voluntarv health organiza- 
tion is another innovative tool that will assure 
the progress of science and of cv stic fibrosis 
research in particular." said Robert J. Beall. 
president and chief executiv e officer of the 
CF Foundation. "CF scientists hav e a great 
track record for collaborating to move CF 
research forward. This continues to fonn the 
cornerstone of our success." 

The Genomax database will be prov ided 
to a limited number of participating cv stic 
fibrosis researchers for free, and these inves- 
tigators will have private v irtual wnrk areas 
w here thev can analv /e their data. Eiv entuallv . 
however, each participating scientist will be 
required to submit his or her data lo the 
central repository, iherehv making it accessible 
to other researchers. 

"Bv providing access to this powerful 
gene analv sis tool and centrali/ed database, 
the CF Foundation hopes that scientists will 
use the tools of functional genomics and 
protein structures to identify nov el targets for 
future drug development." Beall said. 

.According to Fenstermacher. the Cv stic 
Fibrosis National Bioinforniatics Center 
should become available to CF researchers 
this fall. 

Eck, Viall appointed directors 
of women's and children's 
programs 

UNC Health Care recently appointed two 
new program directors for its N.C. Women's 
and Children's hospitals, currciitlv iiiuici 
construction. 

.Sharon Fck has been named director of 
the N.C. Women's Hospital. Carolyn Viall 
has been named clinical mirsing ilireclor lor 
Chiklien's Services. 

Before coming to L'.NC last summei. I:ck 
served as project manager of Senior Nursing 
Administration and Patient Care Serv ices at 
Yale-New Haven Hospital in New Haven. 
Conn. She said the challenge of tailoring 
programs offered in a brand-new. state-of- 
the-art facilitv attracted her to Chapel Hill. 




Lck 



"We're going to 
respond to what 
w omen w ant." she 
said. "We're going 
to give them chitic- 
es. shared 

Llecision-m.iking. 
convenience and a 
caring, human con- 
nection." 

Eck received her 
hacheUtr's of sci- 
ence degree in 
nursing in U)8.^ and 
her master's degree in nursing in l9Sft from 
the Universitv ot Iowa. She 
earned her doctorate in nursing from '^'ale 
University. 

•An assistant professor in the UNC School 
of Nursing. Eck sits on the National 
Research Committee of the .American 
Association of .Ambulator) Care Nurses. She 
is a member of the .American Nurse's .Asso- 
ciation. 

Viall comes to 
LINC from the 
Medical Univer- 
sity of South 
Carolina, where 
she served as 
nurse manager of 
the Pediatric 
Medical-Surgi- 
cal. Pediatric 
Oncolog). 
Pediatric l:n- 
docrinc and 
Renal, and Pedi- 
atric Cardiac units. 

"We aim to deliver world-class caie. ami 
we want lo be the top choice among parents 
aiul lelerring ph) sicians for pediatric care." 
she said. 

Viall earned her bachelor's degree in nurs- 
ing from Cleveland State Univeisit) in I'JSI 
and her master's degree in nursing from Case 
Westeiii Reserve Univeisit) in IMSd. 

.A member of the .American Association of 
Critical Care Nurses. Viall serves on the 
■Amencan Sociel) for Parenteral and linteral 
Nutritions Public Policv Committee. In 
l'^>S. she was awauleil the South Carolina 
League lor Nursing Award ol l\ccllcncc. 

1.^ 




Violl 



Family Day 2000 



Under perfect Carolina 
blue skies, a large crowd 
enjoN'ed Family Day ac- 
tivities held Sept. 16 at 
UNC's Carroll Hall. 

School of Medicine Dean Jeffrey 
I.. HoLipt welcomed almost 500 stu- 
dents, family and friends, one of the 
biggest groups e\er to attend the 
e\ent. Other faculty members par- 
ticipating in the program included 
GeiT) S. Oxford. PHD. professor of 
cell and molecular physiology; 
Georgette Dent. MD. associate 
dean for student affairs. Stephen J. 
Ki/er. MD. professor and associate 
chair for medical education; 
and Beat Steiner. MD. MPH. clini- 
cal assistant professor of 
family medicine. 

James B. Brame. Jr.. of Durham, 
who's daughter Amy graduated m 
199S and now daughter Anna is a 
first year student spoke to parents. 
Brame told parents that the life of a 
medical student revolves around 
four "S" words: study, stress, sacri- 
fice and sleeplessness. 

"These words are easy to under- 
stand and we all know that our fu- 
ture doctors experience all four in 
prescription doses. We can help 
them w ith another "S" word. That is 



support. ... I ask each of you as par- 
ents to seek out and find opportuni- 
ties to volunteer your time and 
talents to the medical school." 

Follow ing lunch cm the lawn, 
first year students and families ad- 
journed to Memorial Hall for the 
traditional White Coat Ceremony. 
This year's speaker was Stewart 
Rogers. MD. professor of medicine 
w ho leads the Internal Medicine 
Training program at Greensboro's 
Moses Cone Hospital for AHEC. 

The White Coat ceremony origi- 
nated at Columbia Uni\ersit\ 's 
College of Physicians and Surgeons 
seven years ago. 

The ceremony is designed to fos- 
ter the ideals of humanistic, com- 
passionate patient care, ethical 
conduct, and personal responsibili- 
t\ in the learning of medicine. UNC 
held its first White Coat Ceremony 
in 1996. About 160 first-year med- 
ical students received their coats 
during the ceremony before a 
standing-room only crowd. The 
ceremony concluded with the stu- 
dents reciting The Oath (see next 
page) dedicating themselves to 
the responsibilities of a physician 
intrainins:. 




Gcoviicnc Dent. Ml), ilsmk uilc Jciin Jcr sludcnl iilhiirs. hikes 
a lii^hr-hcarteil moment ihiriiig her presentation as part of the 
Family Day program. 




Sliulents i^et chance to catch up with taiiiilx at lunch. 



.\ stiuleiit panel shares perspective of medical school life with parents who 
attended Familx Da\ events. 




Snulfiu^. fciiuilx and tru-nds hud 'lunch on die hiwn " mnsidc Currod Hidi 



The Oath 



I acknowledge and accept the privileges and responsibilities 
i;iven to me today as a physician in training and dedicate myself to 
provide care to those in need. 

I will approach all aspects of my education with honesty and in- 
tegrit\: embracing opportunities to learn from patients, teachers 
and colleagues. The diversity of their experiences, cultures and 
beliefs will enrich my education and my alvlity to car for patients. 
When I feel unprepared for new responsibilities. I will 
acknowledge my limitations and seek guidance. 

I will respect the humanity, rights and decisions of all patients 
and will attend to them with conipassiim and without bias. I will 
maintain patient confidentiality and be tactful in my words and 
lU tions. I will not forget that there is an art to medicine as well as a 



science and that warmth, wiiipalhx and understanding are inte- 
gral to patient care. 

I recognire the privileges afforded me as a physician in training 
and promise not to abuse them. I will .urive to earn the tni\i m\ 
patients place in me and the respect that society places upon ni\ 
profession. As a student. I will .'ieek to acc/iiire the kiunvledge and 
skills needed for individual patient care, the capacitx to prevent 
illness and to understand the wars that I can contribute to the stan- 
dard of health in my community. 

.As I accept these new responsibditics. I will not loiget the im- 
portance of my own health and well-being. I will continue to value 
mx relations with those who have supponed mc in the pa\l and 
those who will share in nn jiiuirc. 









Students recite The Oath ihiriif^ the White Coat Ceremon\ held at Memorial Hall. 




Fivhiin^cr 



Faculty 

Notes 



Robert A. Bashford, MD. clinical associ- 
ate professor of psychiatr\. has been elect- 
ed to the membership of the American 
College of Psychiatrists. 

Janet K. Freburger, PhD. PT. has been 
selected as the 2000 
recipient of the 
Dorothy Briggs 
Memorial Scientific 
Inquiry Auard from 
the American Physi- 
cal Therap\' Associa- 
tion. Freburger has 
also been selected to 
recei\e a National 
Research Service 
Award from the Agency for Health Care 
Policy and Research of the U.S. Public 
Health Ser\ ice. beginning in Jul\ 20()(). 

Noelle A. Granger, PhD. professor of cell 
biologs and anatomy, has recei\'ed a grant 
from the Educational Technology Group 
for the purpose of de\elopment of gross 
anatomy dissection guides using comput- 
er-based resources with the aid of Jesse 
Cannon. Granger also received a grant 
from ETG to develop 3D embryology ani- 
mations. 

Gail E. Henderson, PhD. and Nancy 
M.P. King, JD. both professors of social 
medicine, are leading 
a group of colleagues 
who ha\e been aw ard- 
ed a three-year. 
$975,000 National 
Human Genome 
Research Institute 
grant to in\estigate 
ethical issues sur- 
rounding gene trans- 
fer studies. Hender- 
son. King and colleagues will interview 
investigators, research subjects, study 
coordinators and members of institutional 
review boards in up to 50 of the most 
recent gene transfer studies across the 
L'nited States. The group will also analyze 
the specific language of consent forms in 
such studies in an effort to understand how 
people develop ideas and beliefs about 
possible benefits from gene 




Henderson 




KIni; 



transfer/research 
studies. .Also 

involved in the pro- 
t arc Larry R. 
Churchill, PhD. pro 
lessor of social medi- 
cine; Daniel K. Nel- 
son, MS. associate 
professor of social 
medicine and pedi- 
atrics; Arlene Davis, JD. research assis- 
tant professor of social medicine; and 
Michael O. Calloway, a fellow at the 
UNC-CH Cecil G. Sheps Center for 
Health Services Research. 

Celia R. Hooper, PhD. clinical professor 
of speech and hearing sciences, has been 
honored bv L!NC-Greensboro's School of 
Health and Human Performance with its 
Distinguished .-Xlumni Award. 

Jean M. Lauder, PhD. professor of cell 
biology and anatomv. has recently received 
two awards. NIDCR has granted Lauder a 
five-year award titled "Serotonergic Regu- 
lation of Insulin-Like Growth Factors." 
NIEHS has funded ""Organochlorine Pesti- 
cides and Serotonergic Development." a 
two-vear aw ard. 

John J. Lemasters. MD. PhD. professor 
of cell biology and anatomy, has been 
granted a two-year Collaborative Funding 
.Assistance Program award from the N.C. 
Biotechnology Center for his research pro- 
ject titled "Development of Carolina Rinse 
Solution." 

Jeffrey .\. Lieberman, MD. professor and 
vice chair for research and scientific affairs 
of psvchiatry. and Christine Marx, MD 

received the 2000 Kempf Award from the 
American Psychiatric 
Association. The award 
recognizes research 
excellence in schizo- 
phrenia, and is given to 
an outstanding mentor 
and his/her mentee. 
Lieberman recently 
served as part of the 
planning board for the 
Lichcmuin Surgeon GeneraLs 




Report on .Mental Health. 

Gary B. Mesibov, PhD. professor of psy- 
chiatrv and director of TEACCH. has 
received an honorary doctorate from the 
academic board of the Univ ersity of Mons- 
Hainaut in Mons. Belgium. The Belgian 
university recognized Mesibov for univer- 
sity training and public school implemen- 
tation of TEACCH methods in Belgium. 
TEACCH was the first program in the 
United States to offer comprehensive and 
community-based professional assistance 
for families to help them understand and 
treat autism and avoid unnecessary institu- 
tionalization. 

Anthony A. Meyer. MD, PhD. professor 
and div ision chief of 
general surgery, has 
been named the 
Roscoe Bennett Gray 
Cowper Distin- 
guished Professor of 
Surgery. He succeeds 
George Johnson. MD 
who was the first 
Cowper Professor, 
and who now is the 
Roscoe Bennett Gray Cowper Professor- 
Emeritus. Mever has also been appointed 
reviewer for the Journal of Leukocyte 
Blolo\;y. chairman of the Honors 
Committee. Nominating Committee and 
Committee on Publications for the Ameri- 
can Association for the Surgery of 
Trauma, and was appointed to the Strate- 
gic Planning Task Force for Ambulatory 
Care Pharmacy last year. 

Michael R. Mill, MD. professor of 
surgerv. has been named chief of the divi- 
sion of cardiothoracic surgery. He has been 
the acting chief 
since Benson R. 
Wilcox. MD. 

retired in 1998. Mil 
performed both the 'Tt3^ 
first heart-lung 
transplant and first 
pediatric heart-lung 
transplant in North 

Carolina. 

Mill 




Merer 





J^^ 



Paul L. Molina. MD. associate professor 
ol radiologv uas 
selected by the diag- 
nostic radioiogN res- 
idents as Teacher iil 
the '^ear. The award 
honors a UNC facul- 
ty member who 
makes a significant 
contribution to radi- 
ologN resident edu- 
Moliiui cation during the 

academic year. Molina joined the facult\ 
in 1993 and has ser\ed as the residency 
program director for the department of 
radiiilog\ since 1996. He"s the director of 
computed body tomograph\' and chairman 
of the radiology resident selection com- 
mittee. 

Shoji Osawa, PhD. research associate 
professor of cell biology and anatomy, has 
recei\ed a three-\ear award from NTH 



titled "Desensiti/ation of Cone Visual 
Signaling Pathwa\s." 

Michael D. Peck, .MD, ScD. professor of 
surger\ and director ol the L'NC Ja\cee 
Burn Center, has been appointed to the 
editorial board of the Jounuil of Hum 
Care and RehabUitation. 

The Journal is the official publication 
of the American Bum Association and is 
the only U.S. journal de\oted e\clusi\el\ 
to the treatment and rehabilitation of 
patients with burns. Its original, peer- 
re\iev\ed articles present the latest infor- 
mation on surgical procedures, acute care, 
rehabilitation, reconstruction and burn 
pre\ention. 

Robert L. Peiffer, Jr.. PhD. DVM. pro 

fessor of ophthalmology and patholog\. 
was recentK in\ited to be a \isiting pro- 
fessor at the Western Colleges of .Medi- 
cine and Veterinar\ Medicine. L'ni\ersit\ 



of Saskatchewan. Saskstoon. Canada. In 
addition to participating m patient rounds 
and collaborati\e research with Dr. Bruce 
Grahn. Peiffer ga\e three lectures while 
there. "Ocular .Melanomas in Three 
Species." "The Histopathology of Glauco- 
ma." and "Pigmented Ocular Lesions." 

M. Patricia Ri\cra. MD. assistant pro- 
fessor ol pulmonar\ and critical care med- 
icine, has been appointed go\ernor of 
North Carolina for the .American College 
of Chest Physicians for 2()()()-2()()2. 

Wesley M. Wallace. MD. clinical assis- 
tant professor of emergency medicine, has 
been appointed bs House Speaker James 
Black to the North Carolina Legislature's 
Smart Grovsih Commissiim. 



Robert D. Lansdell. MD. professor 
emeritus of patholog\ and laboratory medi- 
cine at the UNC School of Medicine for 
more than 30 years, passed awa\ April I 1. 
2()(M). Despite his death at age 7ft. his life- 
time of contnbutions to the fields of hema- 
tolog\ and pathologs will continue to li\e 
on. 

"Dr. Langdell was one of the three 
world-famous coagulationists that UNC 
has produced." said Harold R. Roberts. 
MD. distinguished professor of medicine 
and pathologN and laboratory medicine. 
"Dr. Langdell. along with Dr. Kenneth 
Brinkhous and Dr. Robert Wagner, is 
known the world o\er for the Partial 
Thromboplastin Time test that the three first 
developed and described in 19.S.\" 

The Partial TTiromboplastin Time test, or 
PTT as many physicians call it. is a simple 
bl(K)d test used for the diagnosis ol bleeding 
disorders and for monitoring treatment ot 
heart attacks and strokes w ith the anticoag- 
ulant heparin. The test is currentls used mil- 
lions of times a day by hospitals worldw ide. 
according to Roberts, and has tormed the 
basis of all other one-stage clotting 
assass used. 



IN REMEMBRANCE 




R,,hcn I) luiir^chll. Ml) 

"Dr. Langdell's contributions lo his licld 
included not only the de\elopmeni of PIT 
and his expertise in the diagnosis of bleed- 
ing disorders." said Roberts, "but also his 
enumeration of the requirements on blood 
banks to treat those disorders w ith blood 
component therapy." 

.•\ graduate of the George Washington 
L'niversit) School of Medicine in I94S. 
Lansidell first came to L'NC as a fellow in 



patholog) in 1944. Hcquickl\ became a 
ke\ member of Brinkhous' research group, 
and began teaching in the department of 
pathology in 1951. His research interests 
included the nature of coagulation in lower 
animals, and the stability of coagulation 
factors in blood-banked blood and plasma. 

Throughout the course of his distin- 
guished career. Langdell was invohed in 
numerous professional affiliations, includ- 
ing the .American Medical .Association, the 
American Society of Clinical Pathologists 
and the International Sociels of Lhrombo- 
sisand Haemostasis 

Langdell retired from the School of 
Medicine in June of 19S9. In 1990. the 
Langdell Transfusion Medicine Service, 
the blood bank for L'NC Hospitals, was 
dedicated and named in honor ol Langdell, 

Langdell's achiev e men is w eie once 
again lecogni/ed in l'>4ft when ihc Ameri- 
can .Association of Blood Banks awarded 
him their highest honor, the Karl I.andstein- 
er .Award. The award is given annuallv in 
recognition of those who have made out- 
staniling contributions iii the science ol 
blooil-banking at both the clinical and basic 
research levels. 



Faculty Profile 



Runge Stays Focused on 



By Katie Macdonald 

During the hottest days of summer, 
w hen many North Carolinians ure 
complaining of the heat and hu- 
midity, Marschaii Runge. MD. 
PhD. and new chair of the UNC 
Department of Medicine, is thoroughly 
enjoying the blue skies and casual, university 
town lifestyle unique to Chapel Hill. "It's 
like a breath of fresh air." said the native 
Texan, who has found relief from the Texas 
heat along with some new challenges that 
come with chairing one of the largest depart- 
ments w ithin the School of Medicine. 

"ril do my absolute best to help the de- 
partment grow and prosper and to foster 
growth in our faculty, fellows, residents and 
staff." he said, ""rm excited to be here and 
will do e\erything I came to help continue 
the outstanding tradition that this department 
has had o\ er the past se\ eral decades. " 

In July. Runge moved his w ife. Susan, and 
their five children. Thomas. 17: Elizabeth. 
1."^; William, 13; John, 10: and Mason. 8. 
from from Gaheston, Texas, where they had 
lived since 1994. in Texas, Runge worked in 
the cardiology di\ ision at the John Seal\ 
Hospital — University of Texas Medical 
Branch at Galveston. Along with his role as 
professor of internal medicine and John 
Sealy Distinguished Centennial Chair. 
Runge ser\ed as the director for the Sealy 
Center for Molecular Biology, all while 
fulfilling his duties as an attending physician. 

His medical career is replete with distin- 
guished academic and hospital appointments. 
He graduated from the Johns Hopkins 
School of Medicine and was an intern and 
resident in Internal Medicine there. He then 
completed his cardiology fellow ship at 
Harvard's Massachusetts General Hospital 
and was a faculty member there prior to 
mo\ing to Emory Uni\ersity as an associate 
professor of Medicine in 1989. 0\erthe 
\ ears, he has recei\ ed numerous aw ards and 
honors that are reflective of his outstanding 
career as a researcher, teacher and physician. 

His research awards include the Henry 

18 




Marschaii Rnui;c. MD. chair of the Department of Medicine 



Christian Research .^ward from the Ameri- 
can Federation of Clinical Research and the 
American Heart Association Council on 
Thrombosis" Young Investigator Prize in 
Thrombosis. 

Runge also has received praise from some 
of the top medical schools in the country. In 
1993, Emory University honored him with 
the Golden .Apple .•\ward for excellence in 
teaching in internal medicine and. in 1994. 
the University of Texas Medical Branch 
designated him the Best Teacher in Internal 
Medicine. The Best Doctors in .America also 
counted Runge among the select doctors for 
its fourth edition issued in 1998. For a doctor 
whose modesty and unassuming 
demeanor might strike some as unexpected. 



although w elcome characteristics. Runge 
has consistently demonstrated an ability to 
manage a lot of responsibilities with the 
highest degree of skill and professionalism. 

Runge"s talents and work ethic, however, 
come as no suiprise to his family and friends, 
vv ho know of his childhood grow ing up in the 
Texas hill country. 

"My parents are both children of the 
Depression and are really big on education," 
said Runge. "They were very insistent 
on getting a good education and putting it to 
good use. The\ never pushed me in 
an\ direction in particular, but did, on occa- 
sion, tell me that if I procrastinated too much, 
they would." 

Althousih Runae was not alwavs sure he 



wading, Teaching, Caring 



u anted to he a doctor, there \\ as strong pull in 
his famils toward medicine — with se\eral 
phvsician I'aniih members, including his 
older sister and younger brother — both of 
\\ hom also ended up in academic medicine. 

Now as a diKtor specializing in cardiolog>. 
Runge finds it amusing to reflect on his original 
vision of becoming a doctor. ""When I first 
thought about going into medicine, my plan 
was to go into famiK practice in a small town 
in central Texas w here my grandparents had 
a ranch." he recalled. ""But in college, some- 
what to my surprise. I became interested in 
basic molecular biology research, and it w as 
that interest that really led me to academic 
medicine. That life wasn't \'ery compatible 
with tamil\ practice in the central Texas hill 
countPv. though."' 

The directum his life has taken is quite 
unlike the life of a family practice doctor in 
central Texas. Although he wanted to attend 
the University of Texas at Austin, Runge was 
encouraged to look beyond the comforts of 
familiarity and home for an education. His 
parents' insistence that he li\e at home if he 
attended LT. proved enough niotix ation to 
send Runge to Vanderhilt University in 
Nashv ille. Tenn.. where he studied biology. 
Vanderhilt is where Runge met his wife 
.Susan, an anesthesiologist. .She's put her 
practice aside for now. concentrating instead 
on being a full-lime mother. ""Susan and I met 
in chemistry class." said Runge w ith a grin. 

.After graduating from Vanderhilt in 1976. 
Runge decided to continue his education 
there and in 1979. completed his PhD in 
Vanderhill's molecular biology program. 
From there. Runge attended Johns Hopkins 
University School of .Medicine, where he 
received his .\H) in I9S4. 

Since that time. Runge has thnveil in his 
position as a physician and researcher, 
devoting much of his career to the study of 
vascular biology and clotting thrombosis. 
"I'm interested in knowing how the blood 
vessels work." he said. 

UNC's long-standing reputation as one of 
the world's leaders in thrombosis research. 
the growing interest here in v.iscuiar hioloyv. 



and the breadth of cutting edge research both 
in the department and medical school are all 
reasons that Runge decided tit come io 
Chapel Hill. "UNC has a wonderful and well 
desened tradition and reputation in thrombosis 
research, and has great science throughout 
the institution." he said. ""Although I hadn't 
initially sought a position as chairman, the 
strength of this department and of UNC and 
the area were practically irresistible. Plus, 
everyone I knew, including several former 
UNC faculty members who were chairs in 
Galveston. realK spoke ver\ highh of the 
institution and area." 

As the new chair of medicine. Runge is. in 
part, responsible for setting the tone for 
students hoping to enter the medical profes- 
sion. He will teach on inpatient services in 
areas of clinical medicine, including his area 
of expertise, cardiology. ""I very much enjoy 
teaching at different levels." he said. ""One of 
our most important teaching roles as faculty 
focuses on the approach to the patient. We. 
and our students, must learn to evaluate 
patients in a scientific w ay in order to consider 
all possible disease processes and treatments 
while never losing sight of the impoilance of 
compassion and the phv sician-patient rela- 
tionship. Helping medical students and hous- 
estaff learn these lessons in today's more 
hurried medical environment is a challenge 
that we must address." 

Runge plans to combine his scieiiiilic 
instruction with an emphasis on profession 
alism and respect for patients, their families 
and coworkers in health care. ""The best 
approach, in my opinion is lo leach interac- 
tively and by example." he sav s. 

Runge wants also to leach medical 
students in the pre-clinical vears. focusing on 
the application of basic science to the 
practice of medicine. ""In the past. I have 
taught in physiology and pathophysiology 
courses on the heart and blood vessels, and I 
hope to be do the same here." he said. 

Along w ith his duties as a tacullv member 
111 the School of Medicine. Runge will spend 
a significant amount of lime with the mctlical 
houseslall \\\n In lliice davs a '.'.cck. kuiii.'e 



will attend a conlcieiice called Morning 
Report and then answer questions at 
bi-weeklv "Stump the Chair" sessions. 

"The job of chairman is a truly daunting 
task, particularly w ith the ever-changing 
health care environment." he said. ""Today, it 
is not only important to be involved in all the 
traditional areas of academic medicine, but to 
alw ays have an eye towards adapting to the 
changing landscape. Thinking back about 
some of the incredible chairs that I have 
know n. as well as those w ho have preceded 
me here, these indiv iduals somehow com- 
bined teaching, clinical care and research in 
their own lives and integrated these into their 
departments. They not only led by example, 
but also faced the administrative challenges 
of managing a large and important part of a 
medical school through challenging times in 
academic medicine. Without question, this is 
a much larger job than anv one person, and 
we have a wonderful faculty at UNC and 
div ision directors, all of whom have alreadv. 
and continue to rise to the occasion." 

Runge's relocation and new job mav seem 
lo him like a breath of fresh air. but it is 
Runge who will breathe new life into the 
department of medicine. "I think we have to 
lake a fresh look at medicine." he said. "Willi 
the collective brain pow er of the departmenl 
of medicine. I have no douhl thai if we are 
w illiiig lo be miiovalive. lo lake risks aiul lo 
persisi. we can make changes that will allow 
all of us to spend more time on what we 
entered academic medicine for in the fiisi 
place — to do research, lake care of palicnls 
and leach." D 



Scholarship Established in 
Honor of Harold Roberts, MD 



BvBernadetteGillis 

Sa\ ing ihank you lo one man never 
meant so much to so many. In appreeia- 
iii>n of years of support. Ron Neal. 
MD, "75. an OB Gyn in Greensboro. N.C.. 
created a scholarship to help medical school 
students in honor ol' Harold R. Roberts. MD. 
".'^.'^. The scholarship endowment fund is held 
at The Medical Foundation of North Caroli- 
na. Inc. 

"Harold Roberts was not onl\ a mentor to 
me but also a father figure. Neal said. "E\er 
since I was in medical school. I ha\e wanted 
lo thank him. The most significant thing I 
could to do was to set up a scholarship." The 
Roberts Loyally Fund Scholarship was an- 
nounced by Neal with Roberts standing at his 
side at the Spring Medical Alumni Weekend 
Banquet. 

The need-based scholarship, named after 
Roberts, will benefit medical students u ilh 
llnancial need. 

Ha\ ing come from disadvantaged back- 
grounds, helping economically disadvan- 
taged medical students would mean a lot \o 
both Neal and Roberts. Neal said. "We both 
know what it was like to staiggle. That's the 
reason for setting up a need-based scholar- 
ship." He added. "ll"s a way of helping those 
like him and mvself." 

It was Robeils' understanding of financial 
struggles that led Neal to find a role model in 
Roberts. "Hav ing lost my father a at \erv 
voung age. it was easv for me to admire 
him." 

Neal worked w ith Roberts for three vears 
before attending the school of medicine, first 
as a technician and later as a graduate stu- 
dent. "Dr. Roberts was personally interested 
in my work and helped me realize my dream 
of becoming a physician." 

Roberts taught Neal many lessons in life, 
including the importance of the being the 
best at w hat you do despite your occupation 
or background, said Neal. "I am certain that 
Dr. Roberts and 1 share the belief that men 
and women of character, intelligence and 
commitment should be able to pursue c;u"eers 
in medicine, regardless of economic circum- 
stances." 



]() 




Hiimlil Rdhcrts. MD. left, learns of Ron iWcal's \c/iol(ir.\hip i;ifr. 



The Harold R. Roberts Loyalty Fund 
Scholarship will benefit one student each 
year beginning in the fall 2001 . The scholar- 
ship is one of .'i 1 Lovalty Fund Scholarships 
awarded annually by the Loyalty Fund, the 
unrestricted annual fund of medical school 
alumni. A campaign is underway to endow- 
all .^1 scholarships at a minimum of 
$100,000. Rising costs, including a signifi- 
cant tuition increase, make the case for en- 
dowment. A story will appear in the next 
Bulletin in regard to the Medical .Alumni En- 
dow ment Campaign. 

Neal said he is happv the scholarship will 
benefit medical students w ith backgrounds 
similar to his. "It's a wonderful feeling lo 
know vou are helping others, and this is a 



w onderful oppoiiunitv to help." 

In addition to show ing his appreciation for 
Roberts' infiuence. Neal said the scholarship 
was established also to recognize Roberts' 
contributions to the school of medicine. "Dr 
Roberts is one of the medical school's great- 
est advocates, and he's made a tremendous 
difference." 

Ri)berts has serv ed on the school of medi- 
cine faculty as an internationally recognized 
specialist in hematology and coagulation. He 
was also granted the Distinguished Career 
.Award for Contributions to Hemostasis by 
the International Societv on Thrombosis and 
Hemostasis. He w as honored w ith the Med- 
ical .Alumni .Association's Distinguished 
Serv ice .Aw aid earlier this year. 



UNC Professor Endows 
National Prize in Neuroscience 



One of UNC's most distin- 
guished researchers recenii\ 
endowed ii SlO.Ooi) 
national prize to he awarded 
annuall) tor an outstanding scientific 
contribution to neuroscience. 

Edward R. Perl. MD. Surah Graham 
Kenan professor of cell and inolecuiar 
ph\ siologs said he endow ed the prize 
to draw attention to UNC"s strengths 
in neuroscience and pa\ tribute to the 
uni\ersity 

"The prize allow s me to acknow I- 
edge the uni\ersit\ for the opportuni- 
ties it has gi\ en nie." he said. "The prize 
would bring to the campus on a yearl\ 
basis major contributors in the field to 
receixe this aw ard. gi\e a lecture and 
interact w ith people here. 

"The prize would be a legacv of nn 
ha\ ing been here and would help call 
attention to the institution and our 
strength in neuroscience." 

Perl said he hoped the prize would 
be awarded for an outstanding disco\ - 
cry or seminal insight, rather than to 
commemorate a lifetime bod\ of work. 

"The selection committee would 
choose from the broad field of neuroscience 
ranging from de\ elopment to molecular 
mechanisms to integrative function." he said. 
"It is m\ specific w ish that the prize should 
not focus on the same area in successive 
\ears. The concept is to recognize people 




aid R. Perl. MD 



ind 



w ith fresh and current contribution 
make them aw are of UNC." 

Perl, who received his medical degree in 
1 949 fn>m the Uni\ ersily of Illinois at Chicago. 
tv\ice served as acting head of the L'ni\ersit\ 
of Utah's physiology department. Recruited 



to Carolina to build up the uni\ersit\ s 
strength in the neurosciences. Pei 1 
served as chairman of |ilivsiologv from 
1971 to 1989. 

A founder and acting president w hen 
the Society for Neuroscience w as start- 
ed in 1969. he was awarded that group's 
1998 Gerard prize for outstanding con- 
tributions to the field. 

Perl's wiirk in pain mechanisms has 
been highlv influential. He was the first 
to document the existence of nocicep- 
tors, sensorv fibers speciallv activated 
bv tissue damage and their relation to 
the sensation of pain. He 
continues to explore the biological 
bases of pain sensation. 

Nearing completion on campus 
is a S3()-million Neuroscience 
Research Center, headed bv William 
Snider. MD. a pioneer in the action of 
nerve grovMh factors, proteins thai help 
neurons grow. Perl helpei,! rcciuil 
Snider to UNC. 

"His nociceptor work has had an 
enormous impact on modern pain re- 
search." Snider said of Perl. 

"There are nov\ literallv dozens of 
laboratories, as well as biotechnology and 
pharmaceutical companies, studying the 
molecular characteristics of these neurons 
w ith an eye toward developing novel pain 
therapies." D 



Californian wins first Perl-UNC Neuroscience Prize 



.\ California researcher became the first 
w inner ot a national prize endowed bv a 
distinguished scientist at the University of 
North Carolina at Chapel Hill. The prize, to 
be awarded annuallv. recognizes outstand- 
ing scieniiflc contribution to the Held of 
neuroscience. 

The SIO.OOO Perl-UNC Neuroscience 
Prize goes to Oav id Julius. PhD. professor 
111 cellular and molecular pharmacologv at 
ihe I ni\i.-isil\ cil { '.ilitiirnia-San IraiKisco 



School of Medicine. 

Julius discovered the nerve cell mole- 
cule that mediates responses to capsaicin, 
the active ingredient in hot peppers. The 
capsaicin receptor. VRl. also is responsi- 
ble for the transmission of noxious heal 
sensations. 

I hat discover) four vears ago. and 
Julius" subsequent studies, build on the pi- 
oneering research of neurophvsiologist |-d- 
ward k Perl. Ml). S.ir.ih Giahaiii Kenan 



professor of cell anil molecular phv siologv 
at UNC's .School of Medicine, 

Julius said he was lionoieil lo have le 
ceived theavsard. 

"I lake great pride and pleasure in being 
named the recipient of the first Perl-UNC 
Neuroscience Prize." Julius said. "Ol 
course, this prize is made possible through 
the generosity of Fid Perl, but it also rellecls 
his pioneering studies in the area of noci- 
ception and sensorv iieunin liinclinniiiL' " 



Research 
Briefs 



Research shows radiologists 
will need different programs 
for digital mammography to 
work best 

For doctors to take best ad\ antage of new 
digital mainiiiography and possibly saxe 
more women from breast cancer, companies 
that manufacture the technology need to cre- 
ate new. more sophisticated computer pro- 
grams. University of North Carolina at 
Chapel Hill scientists say. 

That's because a team of researchers led 
b\ Htta Pisano. MD. professor of radiology, 
has found that radiologists prefer different 
kinds of images for c\ aluating different types 
of breast tissue ahnonnalilies. 

""Before v\e did our study, we thought that 
a ceilain type of lesion and a certain kind of 
breast density, for example, would require 
only one type of processing." said Pisano. 
also chief of breast imaging and a member of 
the UNC Lineberger Comprehensix e Cancer 
Center. ""Now. we think displaying images 
w ill be more complicated. To get full use out 
of digital mammographs' machines, compa- 
nies are going to have to put some resources 
into optimizing images for different tasks." 

■An image processing program that reveals 
calcitlcatiiws in the breast will be different 
from one that helps doctors evaluate those 
calcifications once they've been found, she 
said. The same holds true for cancerous 
breast tumors. 

A report on the latest research appears in 
the September issue of Radiologx,. Besides 
Pisano. authors are Elodia B. Cole, reseaich 
associate in radiolog\ : Stacey Major, fomier 
research assistant in biostalistics: Shuquan 
Zong. graduate research assistant; Bradle\ 
M. Hemminger. senior research associate in 
radiologx ; Keith E. Muller. PhD associate 
professor of biostalistics; and 27 co-authors 
iVoni the International Digital Mammogra- 
phs De\ elopment Group. The latter is a con- 
sortium of radiologists from UNC. Harsard. 
Johns Hopkins. Duke and other uni\ersities. 
■A companion report in the September issue 
o{ Radiographics contains images from the 
studs. 

The lescarch insohed showinc imaees 



Worn 2S patients w ith various known breast 
abnormalities to 12 radiologists who com- 
pared digital images from three different 
commercially asailable machines to tradi- 
tional film mammograms from the same pa- 
tients. The physicians were asked to decide 
and record which images they preferred in 
making diagnoses. Manufacturers were Gen- 
eral Electric. Fisher and Trex. 

The challenge for General Electric and the 
other companies will be to create new. more 
sophisticated computer sitftware that takes 
into account what radiologists beliese pro- 
vides the most helpful pictures, the ph\ sician 
said. 

The National Cancer Institute, the U.S. 
Amiy Medical Research and Material Com- 
mand and the Canadian Breast Cancer Re- 
seiuch Initiatis e supported the research. 

For more information, see lutp://w\vw. 
iinc.edii/ne\\s/newssen'/resecircli/piscmoH3l 
on. htm 

Camera to detect early signs 
of lung cancer; tests at 
UNC seek people at risk 
for disease 

Physicians at the Ihiisersity of North Car- 
olina at Chapel Hill School of Medicine are 
seeking people at high risk for deseloping 
lung cancer to participate in a studs' aimed at 
detecting early signs of the disease. 

■"We are looking for people svho has e a 
prior history of early-stage lung cancer, head 
or neck cancer, smokers os er age 35 and 
smokers svho base had relatises svith lung 
cancer."" said Patricia Risera. MD. assistant 
professor of medicine and a member of the 
UNC Lineberger Comprehensise Cancer 
Center. ""Our hope is that sve ss ill be able to 
detect cancers at a much earlier stage svhen 
sve knoss ihc chance of treatment success is 
better." 

The study, w hich is in collaboration ss ith 
scientists from the National histitute of Ens i- 
ronmental Health Sciences, involves a cam- 
era de\ ice called LIFE, for lung imaging 
fluorescence endoscope. 

UNC phs sicians base been using the LIFE 
unit, ss hich is approsed bs the U.S. Food and 



Drug Administration, for more than a year to 
detect pre-malignant or malignant changes 
inside the lungs. UNC is the only facility in 
North Carolina svith the device. 

Created in Vancouver. Canada, by Xillix. 
the LIFE bronchoscope is an improvement 
over conventional bronchoscopy. X-rays or 
sputum tests. It uses red or green light svaves, 
causing normal cells to appear bright green. 
Abnomialities. such as pre-cancerous lesions 
and tumors, shoss up as sarying shades of red 
orbrossnish red. 

"'It is more sensitise than the traditional 
white-light bronchoscopy for precancerous 
lesions." Rivera explained. ""'With the svhite- 
light method, even an experienced hroncho- 
scopist can miss a lesion." 

This improsed sensitivity means physi- 
cians can encourage patients svith early signs 
of cancer in their lungs to adopt ness and 
healthier life habits. 

■"By catching tumors that are precancer- 
ous, we can make intersentions and also en- 
courage patients to stop smoking."' Risera 
said. "'We beliesc that some pre-malignant le- 
sions may regress if patients stop smoking." 

For more information, see http://www. 
iinclicalthcare.org/medsys/news/new.sreleases/ 
ne\[\release.cfi}i/rele(ise=life_l'>romhoscope. 
Iitnil 

Hearing loss a threat to 
children who survive 'stiff 
lung' condition at birth, 
UNC physician finds 

Children ss ho surs ise a condition at birth 
in which their lungs are too stiff to saturate 
their blood w ith enough oxygen mas be at in- 
creased risk for progressise hearing loss and 
need perii)dic hearing tests, according to a 
University of North Carolina at Chapel Hill 
physician. 

Newborns ssiih the potentialls life-threat- 
ening condition called persistent pulmonary 
hvpertension. or PPHN. usually are put on 
mechanical s entilation s ia a breathing tube. 

Surs is ors of PPHN need folloss -up moni- 
toring ss ith periodic hearing tests, even if 
standard auditory testing in the first ss eeks of 
life prose normal, according to Wendell G. 



■^arbrough. MD. assistant professor of oto- 
lan, ngology and head and neek siirger). 

in the United States, about ID.IMM) babies a 
year are bom \\ ith this disorder. 

Writing in the .August issue of Airhivi's of 
Otoliii-Mifiology. ^'arbrough makes his point 
describing the ease of a child with dekiyed- 
onset hearing loss 

'".As a neuborn. this child had sur\ i\ed 
persistent pulmonar\ hypertension. He was 
treated in neonatal intensive care and after 
discharge from the hospital had done fine on 
regular pediatric examinations." ^'arbrough 
explained. "He also did well on standard de- 
Nekipmental tests at se\en and 1.^ months. 
These showed nomial response to sound, but 
did not include fomial audiologic testing. 

"But w hen he was about 3 years old. his 
parents brought him to our clinic because 
they were concerned that the child might 
ha\e poor hearing. They had noticed the dif- 
ference in speech dexelopment between their 
older child." 

The parent's concerns were justitled. The 
child communicated w ith poor articulation, 
and hearing tests resealed moderate to se\ere 
bilateral sensorineural hearing loss. Auditor) 
simctures w ithin his ears essentially w ere not 
detecting sound signals for ner\e transmis- 
sion to the brain. 

"We titled him w ith hearing aids and sent 
him to speech pathology for a fonnal speech 
and language evaluation. He had a vocabu- 
lary of about 50 words, compared with 900 
words ty pical of 3 y ear olds." Varbrough 
said. "Auditory comprehension, expressive 
communication and total language score 
w ere consistent w ith a one-year delay in 
s[X'ech and language skills." 

The boy was enrolled in speech therapy 
and followed by an audiologist for hearing 
e\ aluation and refitting of hearing aids. 
\N hen he was seen again in the clinic six 
months later, his viKabulary had increased to 
2f^i) words. But tests demonstrated a progres- 
sion in hearing loss. 

In his journal report, 'i'arhidugh acknowl- 
edged a growing body ot data supporting a 
link between PPHN. its medical treatment 
and hearing loss. 

"The issue is clouded to some degree be- 
cause a lot of these children were on different 
types of ventilation support or on drugs such 



as gentamycin |an antibiotic], which have 
been associated with hearing loss." he said. 
"But I think it's becoming clearer that the un- 
derly ing insult is not necessarily what we do 
to the child but the disorder itself. PPHN." 

For more information sec 
htip://\vww.imchealthcare.orf>/mfdsys/ue\\s/ 
newsrelcases/ne\\srelease.cfm/release=sliff 
_luni;.liinil 

New protein key to cell 
shape and movement; 
has implications for 
cancer, pregnancy, brain 
development, wound healing 

.A protein discovered by scientists at the 
University of North Carolina at Chapel Hill 
appears to play a key role in delennining the 
shape of cells and allow ing them to move. 

The newly identified protein, called pal- 
ladin. is being explored for its inlluence on a 
number of biological processes, including 
the invasive spread of cancer, wound healing, 
brain development and the implantation ot 
the embry o in the uterus. 

"I think it may be critically involved in 
even more biological functions." said Carol 
A. Oley. MD. assistant professor of cell and 
molecular physiology. A report of the dis- 
covery, co-authored by Mana M. Parast. MD. 
of the University of Virginia, was published 
in the Aug. 7 issue of the Journal of 
Cell Biology. 

Otey said the new protein was named after 
Palladio. the intluential I6th-ccnluiy archi- 
tect. Palladin appears to be quite involved in 
the architecture iif cells, specifically via 
the actin cy toskeleton. a polymer protein 
complex that ihovkIcs much of the basis for 
cell shape. 

"Cells have a shape that is ivlalctl to iheir 
luiictioii." Otev explained. "A good example 
of specialized cell shape is the neuron. They 
must be very long and skinny to allow the 
nervous system to lunclion. .Another exam- 
ple is epithelial cells, including skin cells, 
which bind tightly to one another lo form a 
continuous sheet." 

.According to Otey 's findings, palladin be 
longs to a small group of cy toskelelal atllic- 



sion proteins that seem to prov ide molecular 
'glue" for maintaining cellular shape and for 
the attachment of cells to one aiuuher v ia 
their plasma membranes. For example, fi- 
broblasts are spindle-shaped cells involved in 
connective tissue and collagen tbmialion and 
also are crucial to wound healing. In these 
cells, palladin is concentrated near attach- 
ment points to the plasma niembranc. 

On the other hand, palladin is abseni. not 
expressed, in some undifferentiated cells; 
that is. in cells which haven"t achieved their 
genetically predetermined shape. Thus, the 
protein is absent in precursor stem cells. 

"So this indicates that palladin play s a role 
in fomiing the new cy toskeleton of cells that 
are beginning to differentiate and take on 
their specialized shape." she said. 

.According to Otey. an exciting thing about 
palladin is its presence in different torms. 
different molecular w eights. 

"In many different types of cells, one 
lorm of palladin may be necessary for tight 
adhesion and another for migration, or move- 
ment."' she said. 

She noted that a heav ier fonii of palladin is 
more highly present, or expressed, in 
metastatic cancer cells — tumor cells that 
spread beyond their point of origin. 

This research is supported by grants from 
the National Institutes of Health. 

I-oi more intormation see hup: 
//\\w\\.:uneiiealtiuare.org/meds\s/news/news 
releases/new sii'lease.cjin/n'lease=ixilladin.html 



23 



Development 

Notes 




Tile-painting endeavor 
to raise money for 
N.C. Children's Hospital 

A unique parlnership between the 
N.C. Children's Hospital and a Chapel 
Hill business will raise money for the 
liospiiaTs pediatries program. 

"Hands and Heels for Hope" is 
a pri)gram eo-sponsored by Paint the 
Earth, a paint-it-yourself eeramie studio 
in Chapel Hill, and The Medieal Founda- 
tion ol' North Carolina. Ine. Paint the 
Earth is ottering a special tile-painting 
opportunity that will give artists long- 
term recognition and pro\ide financial 
support to the N.C. Children's Hospital. 

Through "Hands and Heels lor 
Hope." artists can paint 6-inch square 
tiles that will be permanently moLuited in 
the lobby of the new N.C. Children's 
Hospital. The cost is $25 for one tile or 
,S40 for two tiles. Proceeds benefit the 
N.C. Children's Hospital. 

Paint the Earth will donate 
all tiles and supplies, and will gla/e and 
fire the llnished works. 

Indi\iduals are encinuaged to \isii 
Paini ihc Harlh at ."^16 \V. Franklin .St. 



— |usi be suic to icll a studii) staff mem- 
ber the purpose of your \ isit. Handprints 
and footprints of children are suggested 
figures to paint, but any tasteful message 
or art is welcome. 

The ne.xt tile-painting fundraiser will 
be held Fri, Dec 8, at the Medical Au.xil- 
lary Holiday Bazaar in the lobb\ of the 
N.C. Neurosciences Hospital. 

150 Attend Fall 
Co-Founders' Meeting 

Nearly 150 people attended the Fall 
Co-Founders' Meeting held Nov. 1 I and 
hosted by The Medical Foundation of 
North Carolina. Inc. The Foundation held 
the e\enl al the William and Ida Friday 
Conlinuing Education Center for those 
who have contributed more than SI. ()()() 
this year. 

Co-Fininders' Club President Daxid 
Rendleman. MD '70. presided over the 
meeting v\hich focused on women's and 
children's programs at UNC. A sneak pre- 
\ iew ()f the new N.C. Children's Hospital 
was presented by .Alan Stiles. MD. chair 
of the department of pediatrics. (For more 
inlormalion about the new N.C. Women's 



Mike Bticy. left, a UNC 
senior and head of last year's 
UNC Dance Marathon, 
presents a check for $70,000 
to Eric Mimson. UNC Hospitals 
president and chief executive 
officer { second from left). 
Scarlet Cardwell. director of 
the department of social work, 
and Alan Stiles. MD. chair of 
the department of pediatrics. 
The Dance Marathon is on 
aimiial fundraising eveni 
organized In UNC students to 
benefit the N.C. Children's 
Hospital. Dance Marathon 
2001 will he held in Fchniarx. 



and Children's hospitals see page 4. 

Program highlights included the fol- 
lowing presentations by UNC .School of 
Medicine faculty members: 

"The Center for Maternal and Inlanl 
Health." by Ken Moise, MD. professor 
and division chief of maternal-fetal medi- 
cine 

'Cutling-Edge Techniques of Intrauter- 
ine Therapy." by Nancy Chescheir. MD. 
professor, department of obstetrics and 
gynecology 

"Prenatal Cardiac Diagnosis." by John 
Cotton. MD. assistant professor, depart- 
ment of pediatrics 

"Approaches to Congential Heart Dis- 
ease." by Mark Bleiwiess. MD. assistant 
professor, department of pediatrics 

Co-Founders' meetings provide donors 
information on issues facing the School of 
Medicine as well as new research and 
technology. 



24 



Alumni 

Notes 



20s 



Uni\ersity of Soiiih Carolina in 
Charlesiiin. SC. 



Herman F. Easom, MD "27. li\es in 
Wilson. N.C. and works pari lime ai 
chest clinics for tuberculosis. In 19M7. he 
lost his uife: the two had no children. 



40s 



George Md^eniore. Ml) "46, would 
like lo know how is lellow classmates 
are doinj:. McLeinore continues to prac- 
tice medicine at his cardiolog\ practice 
in New ^'ork Cit\. 



60s 



.|(ie (iriffin. MD "68, retired in August 
Irom the .Medical College of Georgia as 
professor of medicine (gasiroenterolog\ i 
after 2.*^ \ears on the facult\. He plants to 
enter prisaie practice in .Augusta. Cia. 



70s 



I)a\id H. Hopper. .Ml) "76. president of 
Total Life Famil\ Practice Center. Inc. 
and Bill Harden. MD 77. from 
Bluefield. Va.. wrote "we (recentl\) 
worked lor eight da\s in the isolated aiul 
rehcl-controlled lerriiones ol the Nuba 
.Mountains and Blue .Nile districi ol 
.Southern .Sudan, .\lrica." The two treal- 
eti .^.000 patients lor malaria, worms. 
d>senler). iropic.il skin ulcers anil 
numerous other prohlcms. ID see 
photos ol the trip check ihe web siie at; 
h 1 1 |i : //c o m m u n I 1 I e s . m sn.com/ 
missionlosLidan 

Tomm> Pope. .Ml) "78. was recentl\ 
promoted as professor and chair ol ihe 
deparlmeni ol radiologv at the .Meilicai 



80s 



.Vngela Kendrick. Ml) "82, is a pediairi 
anesthesiologist at the Doernbechei 
Children's Hospital in Portland. Or. Sh 
and hei" husband. Biad. unite ainonc 
who \isits Portland to stop b> for a \isii 
.And. bring some barbecuel 

Scott L. Raniey. .Ml) '81. is duel of 
inter\entional radiology with Ba\ 
Radiology Associates. PA in Panama 
City. Florida. His email address is 
SLR.'Sac? aol.com 

Teri Rummans. MD '81. Ii\es in 
Rochester. Mn. where he works in the 
department ol' ps\chiatry at the Ma\o 
Clinic. He was recentK elected presideni 
of the staff for 2001. 



90s 



Ibrez Handukwala. .Ml) '^7. is a mem- 
her of the Hmor\ L'ni\ersit\ Hospital 
ileparlment of medicine facult\. He plans 
lo maiT\ Claire Parker. MD '47. who is 

currently a fourth-\ear resident in oh/gyn 
at Emory Uni\ersii\ Hospital. 

Michelle Kilbv. MD '90. is an assisianl 
jirolessor in pediatrics at the rni\ersii\ 
of .Alabama. She also is the medical 
director ol the child abuse team and 
reccnth recei\eil her masieis in public 
health. She and her husbaiul. Michael, 
have two sons. 
|{r>aii Ne>Mirtb. MI) ••)!, pissed ihc 



.A\er Board of Cosmetic Surgery in .April. 
Nevwirth lives in Hickory. NC. with his 
wife and four children where he works in 
a private oral, ma.xillofacial and cosmetic 
surgeiA practice. 

(;ardiner Roddey. MI) '•>(!, and Patty 
Roddey. .MD "•)(). live in Charlotte. NC 
w ith their sons Rich. 7. Idi. 2 and daugh- 
ter Lvle. ."^ monlhs. Pallv practices 2 1/2 
davs per week. Ciardiner. although he 
works king hours, still finds nme lo plav 
some soccer and basketball. 

Melinda T. Wyatt. MI) '93, and her 

husband Rick, recent l\ welcomed 
Nicholas Tav Kir Wvatlt to iheir family 
this year. Melinda is currenilv in inivaie 
practice in Raleigh. NC. 

Deaths 

Re\ Speers, MD, House Staff. 57-'6I 



25 



2000-2001 Loyalty Fund Scholars 



The Loyulu Fund iiiilialed iIk' Merit 
Award program in 1966 with a modest 
stipend to six students. In the late 1980"s the 
Medical Alumni Association developed a 
strategic vision to promote broader and high- 
er levels of alumni support. Increasing pri- 
vate gilts enabled the number of scholarships 
to grow from 20 in 1 993 to 5 1 currently, each 
ccnering full in-state tuition. The awards for 
2()()0-2()()l are S3. 300 e.\cept for Allied 
Health Sciences, which are $ 1 .500. 



Merit Awards - ,Aii estimated ten awards 
are made for highest honors during MS I. II 
and III. (MS Ills to be detemiined. ) 

Four-Year Scholarships - Twenty-four 
students are supported. Si.\ awards to MS Is 
for four years based on academics, leader- 
ship and financial need. Two are designated 
for MD/PhD students. 

Fourth-Year Generalist Scholarships - 

Fi\e aw aids to MS IVs who ha\e committed 
to a generalist residency program. 



First-, Second- and Third-Year 
Scholarships - Three one-> ear aw aids for 
each class based on academics, leadership 
and financial need. 

Allied Health Sciences - Three aw ards 
for students to be selected b\ the Department 
Chair. 








Jessica Bailey 


Lindse\ Baker 


April Blue 


MS III 


Allied Si wiKfs 


MS l\ 
Foiii-Ycai 




Theodore Brissoii 

MS II 
One-Year 







Jeiiniler Bushman 


Martin Butler 


MS 1 


MS II 


MD/PhD 


Merit 





^^ja 





Jennifer Chancellor Jerome Chen 

.1/5/' MSI 

One-Yetir OiieA'eiir 



Lisa Cohen 


Heather Crouse 


MS 1 


MS III 


Four-Year 


One-Year 





Donna Culton 


C urios hherl 


MS III 


MSI\- 


MD/PhD 


FiHir-Year 




Stephanie Talk 

MS II 
F<uir-)'ear 






Kelly Fogleman 

MS 'll 
One-Year 



Matthew Foster 

MS III 
Four-Year 





Lee Gray 




Jamie Green 

AlludSciciuc 



w 



Duncan Hill 


\oah Hoffman 


MS III 


MS III 


OiuYciU 


MlVI'hD 


v% 


O 


^ 


; ' > 


r^fei 


V . 


Rodney Look ( 


Chad McCall 


A/S /\ ' 


l/.V / 


(hH-)iOr 


MD/I'hli 





Miihail Ro\intlial Jonathan Roiilli 

\t\ III MS III 

Ml) I'lil) h'Ki-Ycai 




>-^^ 








Llizahelh (iiukian Slacy Haponik 

Mlud Scumc^ .MS I 

hour-Yiar 




Jennifer Hunter 

MS III 
Mem 




Dallon McLean 

MS II 

Miiv 




Shaida Ryan 

MS III 
i, mi -Year 







Jt^\ 




Rebecca Sands 
MS III 
OiH-Yan 






Gavin Henderson 

MS II 
MD/Phn 



Michelle Hernande: 

MS III 





I'/'/av Krishnamiirthy Milele Kudumn 

MSI MS II 

(>iu)cui Oiu )c,ii 





Shannon Sawin 

MS l\ 
I. nil -Yen 

I 1 







Jason Merker 


An up Parik 


iMtonia Roach 


MS III 


MS 1 


MS l\ 


MD/PhD 


ilnc-Ycai 


h>lll )cui 




( harle 


\ Smith 


Rishi S\al 


Charles Toulson 


Ixivanya Miidya 


\(iin \o 


Rehccca Walk, 


\/S l\ 




MS II ' 


MS l\ 


MS III 


MS n 


MS 1 


DihYc 


III 


I-niii-Ycar 


OiicYiiir 


Merit 


loin Year 


h.iii Year 



Sara Woods 
MS I 
hour- )c<ir 



11 



Loyalty Fund Campaign 



Loyalty Fund Budget FY 2000-0: 
$705,000 

Student Scholarships and Programs 
S22(i.ll(l() 



Communications 
SI 26.00(1 




Medical Alumni 
Distinguished 
aching Professorship 
S50.000 

lealth Science 

Library and 

Icchnology Support 

S50.b00 



Area Campaigns 
Atlanta 

George W. Cox. .\1.D. '66 Cluiii 

Buncunibr County 

E^ienilcy D. Jeftries, M.D. 'S."; Cliuii 

Durhani/Orange Counties 

W. Woocliou Burns. Jr.. M.D. ■6'-) Co 

Cluui 

\\ Benson .McCulcheon. Jr.. M.D. 

IIS Co Clhiii 

Forsjth County 

Richard C. Wor'f. M.D. 'VS Cluiir 

Cuiiford County 

Drew A. Jones. M.D '^l CoCliuir 

Leigh H. Jones. KLD. '90 Co-Chuir 

Mecklenburg County 

Rob\n StacN-Humprhnes. M.D. 'S? 

Co'chiui 

Bradlev K. Weisiier. NLD. S.S Co- 

Chan ' 

New Hanover County 

John ,\L Herion. M.D.''S.^ Clhur 

Wake County 

H Chllon Pailers.ni til. M.D, '74 

Reunion Campaigns 

Class of 1445 

John R, Pender 111. M.D. Chair 
G. Robert Clults. M.D. 
A. Robert Cordell. M.D. 

Class of 1950 

John .A. Kirklarid. .M.D. Cluiir 
Frederick O. Bowman. Jr.. M.D. 
W. Grimes B\erlv. Jr.. M.D. 
EluoodB. Cole\. M.D. 
John T. Dees. m'.D 
Laurence B. Leinbach. .M.D. 
John L. McCain. M.D. 
Lewis S. Thorp. Jr. M.D. 
Charles R. Vernon. M.D. 
John L. Walters. M.D. 

Class of 1955 

John W. Pousi. M.D. Cluiir 



.Medical Alumni .•\lumni Outreach 
Endowment Fund 5115.000 

$25,000 

•Funds raised in cvijcss <>t hiidj:i.-i dccrcasL- ihc piTtctilai-c 

Har\cy Adams. NLD. 
Julian S. Albergoili. Jr.. M.D. 
Robert G. Brame, M.D. 
Ralph E. Brooks. Jr.. M.D. 
Walter E. Deyton. NLD. 
PreslcN Z. Dunn, Jr.. M.D. 
- J. Eugene Glenn. M.D. 
Ira D. Godwin, M.D. 
James W. Haves 111. M.D. 
Charles L. Herring. M.D. 
William D. Huftlnes. NLD. 
SamuelG. Jenkins. Jr., M.D. 
Samuel B. Jovner. NLD. 
A. Smith Lineberger. Jr.. M.D. 
William L. London IV, M,D. 
Llovd C. McCaskiU. M.D. 
Andrew C. Nliller III. M.D. 
J. Th.iddeus NIonroe. Jr.. NLD. 
G. Ir\in Richardson. NLD. 
C. William Rogers. NLD. 
Roben L. Summerlin. Jr.. NLD 
G. Reginald. Jr.. M.D 

Class of l%n 

Elliott Solomon. NLD. Clmir 
Jefferson D. Bulla 111. M.D. 
John R. Dvkers. Jr., M.D. 
Gerald W Fernald. M.D. 
Robert H. Hackler 111. NLD 
James R. Harper. NLD 
Falls L. Harris, NLD. 
E. Carwile LeRov. M.D. 
J. Gray McAllister 111, M.D. 
K. Franklin NIcCain. M.D. 
William N. Nhchal. Jr.. NLD. 
Cecil H. .\e\ille, Jr.Nl.D. 
Duncan S. Owen, Jr.. NLD. 
Robert B. Payne, NLD. 
Jerrv Nl. Petty, M.D. 
Jean R. Poirier, M.D. 
Elizabeth V. Raft. M.D. 
Hilliard F. Seigler, M,D. 
Robert F. Sloop. Jr., M.D. 
John C. Tavloe, NLD. 
P Bun Nca/e\. NLD. 



NLD. Chan 
NLD. 



NLD, 



Class of 1965 

VVilliani F. Sasers 
James O. Burke. Jr 
Takev Crist, M.D. 
Robert V. Fulk. Jr, 
Charles R Graham. Jr.. NLD. 
Alexander C. Hattawav ML M.D. 
Howard Holderness. Jr.. M.D. 
Joe R Hurt. M.D.. Ph.D. 
Richard E. Lassiier. NLD. 
Gordon B. LeGrand. NLD. 
JohnB. Shinn. NLD. 
Williamson B Strum. M.D. 

Class of 1970 

David A. Rendleman 111. NLD. Chair 

H. Clifford Baggeii. Jr.. M.D. 

Jerrx C. Bernstein. NLD. 

Daniel L. Crocker. Jr.. NLD. 

Charles E. Crumley. NLD. 

H. Shelton Earp lli. NLD. 

James O. Goodwin. M.D. 

C. Brvan Koon. Jr., M.D. 

Edward A. Norfleet, M.D. 

T. Reed Underbill. M.D. 

Class of 1975 

Hoke D. Pollock. NLD. Chair 
Julian C. Brantley 111, NLD. 
Samuel L. Bridgers II, M.D. 
Dallas C. Craven, Jr., M.D. 
Richard F. Fox. M.D. 
Donald G. Gregg, NLD. 
Thomas Higgins. NLD. 
David S. Lennon, NLD. 
Howard A. McNLihan. NLD. 
Michael W. Meriwether. NLD. 
Frank H. Morets. M.D. 
Dan A. Myers, M.D. 
W. Ronald Neal. M.D. 
Marshall H. Odom. NLD. 
Charles J. Parker, NLD. 
H. Wonh Parker. NLD. 
James E. Peacock. Jr.. NLD, 



Wanda L, Radtord. NLD. 
Carol B. Teutseh. NLD. 
E. Brooks Wilkins. M.D. 
Kenneth H, Winter, M.D. 

Class of 1980 

Sandra K. Haiglei. NLD Chair 

Class of 1985 

James W. Ledeier, Jr., M.D. Chair 
Bernard T. Eaton, M.D. 
Margaret K. Fikrig, M.D. 
Catherine G. Fuller. M.D. 
Susan C. Hadler, M.D. 
David V. Janeway, M.D. 
Margaret G. Johnson, M.D. 
Peter M. Jordan. M.D. 
Theodore C Kemer, Jr.. M.D. 
John A. Kirkland.Jr.M.D. 
James E. Manning, M.D. 
Terry A. Morrow. M.D. 
Joel E. Schneider, M.D, 
S. Patrick Stuart, Jr., M.D, 
Sherrie E. Zvveig, M.D. 

Class of 1990 

JohnE. Baiklev. M.D. Chair 
John T Atkins 111. M.D. 
Benila F. Banks. M.D. 
L. Lorraine Basnight, M.D. 
Eh/abcth D. Bell.\l.D. 
VV Lee Bell, NLD. 
Catherine L. Cooper, M.D. 
Wilham De Araujo, M.D. 
Mark T Hooten, M.D. 
HaiTison A. Latimer, M.D. 
Lori B. Lilley, M.D. 
Garv B. Loden. M.D. 
Wanda K. Nicholson, M.D. 
Crvstal J. Pettiford-YeldelL M.D, 
Eus;enia B. Smith. M.D. 
Murphy F. Townsend III. NLD. 
.Anne M. Tra\nor, M.D. 
Craia Wierum, M.D. 
John^H. Wood. M.D. 
Mark W. Zinimemian. M.D. 

Class of 2000 

Stuart NL Hardv. NLD. Co-Chair 
Shawn B. Hocker. .M.D. Co-Chair 
Christopher G. Brow n 
Troy A. Bunting, M.D. 
KeliiG. Coop. M.D. 
Timothy W. Dancv, M.D. 
Cescili A. Drake. M.D. 
Leslie R. Ellis, M.D. 
SonjaT France. M.D. 
S Brett Hea\ ner 
Tracy R Jackson. NLD. 
Ke\mNlLee, NLD. 
Kimberh S. Levin, M,D, 
Susan L. Mareelli, M,D, 
Justin .A. Mutch, M.D. 
Stephen W. North, M.D, 
Nerissa NL Pnce. M.D. 
Douglas D. Rockacv. NLD. 
Karen B. Stit/enberg. NLD. 
T.i\lorH. Stroud, NLD. 



Report to Donors 



Dear Mt'dical School Alumnus: 

It is uith sincere thanks and apprecia- 
tion that I report to \ou that t'lseai year 
1499-2()()() (July-June I was another 
record-setting year for alumni i2i\ing to 
the UNC School of Medicine and UNC 
Hospitals. 

Almost 50 percent of medical alumni 
naiionall\ contributed a total of S2.2 mil- 
lion to benefit UNC School of Medicine 
and UNC Hospitals. Of this amount. 
SI. 5 10. 000 was restricted to support 
much-needed professorships, fellow- 
ships, lectureships and other important 
programs. 

The remaining S69().0()0 was con- 
tributed b\ ?<9 percent of all alumni to the 
l.o\alt_\ Fund, the unrestricted fund that 
pro\ ides support where no other funding 
sources are available. It would take an 
endowment of SI4 million to generate an 
annual income of S690.000. This illus- 
trates the significance of alumni support 
in the life of the UNC School of Medi- 
cine. 

The listing that lollows includes the 
names ot all alumni who made contribu- 
tions to an\ Medical Foundation account 
between July I. 1999 and June .^0. 2()()(). 
Names in bold t\pe recognize alumni 
who conlribulcd at the SI. 000 level or 
above. Names in italics recogni/e alumni 
w ho gave SI 0.000 or more. 

Continued alumni participation in the 
l.ovally Fund Campaign plays a pivotal 
role in helping to determine the qualitv of 
programs that the UNC School of Medi- 
cine is able to offer its students and fac- 
ullv each year. Thank you again tor your 
generous support of all programs at your 
alma mater. 

Sincerely. 

June M. McNcci: Asslsttint Dean 
and Vice Picsidcni. 
The Medical imuulaluiu af 
Siirlli Can lima. Inc. 

PS. Please notify The Medical Founda- 
tion at (8(K)) 962-2.54.^ of any corrections 
to this list. We have matle evcrv cllorl 
tor accuracy. 



Hoiuir RoW Of Alumni Di)iK)r; 
1999-2(HH) 

Sl.OOO-Sy.yw doitius ill, pnnttil in hohi 
$IO.O(HI or more iiiv piinhcl in hold Uii/iix 

CL.ASSOF i^z."; 
Number in Class: 2 
Percent Donors: 50.0 *> 

Herman F. Easom. M.D.. WiNon. NC 

CL.A.S.SOF 1924 
Number in Class: 2 
Percent Donors: 50.0 'r 

\ancc T .Alcvander. M.D.. Da\idMin. NC 

CI..\,SS()F 14.M 

Number in Class: 8 

Percent Donors: 25.0 ^t 

Ralpli B. Garrison. M.D.. Hamlet. NC 

J. .\. Whitaker. M.D.. Rocky Mount. NC 

CLASS OF 19.^2 
Number in Cla.ss: 5 
Percent Donors: lO.O'^c 

Georjie P Rosemond. M.D.. Laneansler. PA 

CL.ASSOF 19.U 
Number in Class: 4 
Percent Donors: 50.0'r 

William B. Patterson. ,\I.D.. Wailuku. HI 
Jean R. Sutler. M.D.. Chapel Hill. NC 

CL.ASSOF ly.^.s 
Number in Class: 4 
Percent Donors: 25.0 'i 

Jiilien H, Meyer. .\I.D.. Roanoke. V.A 

CL.ASSOF 14.^6 

Number in Class: 12 

Percent Donors: ISM'^c 

l.andis P Milchell. M.D.. Spindale. NC 

Laura R. Venning. Ml:).. Ctiapel Hill. NC 

.\nnie Louise Wilkerson. \LD.. Raleigh, NC 

CL,\SS()F 19.^7 

Number in Class: 5 

Percent Donors: 20.0'j 

W. .Skellie Hunt. .|r.. NLD.. W ilniinnton. N{ 

CL.ASSOF I9.V; 
Number in Cla-ss: II 
Percent Donors: }()A'"c 

Jesse B, Calduell. Jr., Ml),, (lastonia. NC 
Henry T. Clark, .In, .NLD., Chapel Hill, NC 

l.duin .A. R.isberrv. Jr.. Ml),. Wilson. NC 
Pearl It Sehol/. MI). Balliniore. Ml) 

CI ,\SS Ol 1940 
Number in Class: 2.^ 
Percent Donors: .V).l'r 

Inez W Fliod. M I ) . CliarloHe. NC 
J..hn B Ciraham. M I) . Chapel llill, NC 



Henry C C.uynes. Jr. MI),. Rockwall. T\ 

Joseph \V, K.ihn. MI). Fr.inkhn. NC 

Robert K. Kirkman, M.I)., Key Biscayne, KL 

French H. McCain. .Ml),. Bloonilleld Hills. Ml 
George B. Patrick. Jr. Ml). Silver Spnni;. .Ml) 
John L Ranson. Jr. Ml). Charkuie. NC 
John H Woh/. Ml). Ch.irlone. NC 

CL,\SS()F 1941 

Number in Class: 15 

Percent Donors: ii.i'e 

Robert M. Hall. M.D.. Raleigh. NC 

Jack Hughes. M.D.. Durham. NC 

Claude Lowi") Pressls. M,D.. Charlolle, NC 

Carllon C., Walkins. M.D . Charlolle. NC 

Ernest H. Velton, M.D., Rutherfordton, NC 

CL.ASSOF 194: 
Number in Class: 23 
Percent Donors: 26.1 'r 

Jerrv H, .Allen. M D,. Springfield. MO 
Frederick A. Blount. M.I).. Winsion-Saleni. NC 
John B. McDevitt. M.D.. New >ork. NY 
George W. Plonk. M.D.. Kmgs Mountain. NC 
William Tenenblatl. Ml).. Lake Worth. FL 
R, B Williams. Jr. Ml),. Wilmmglon. NC 

CLASS OF 194.> 

Number in Class: 45 

Percent Donors: 24.4'^( 

James R. Collett. M.D.. Morganlon. NC 

John C. Foushce. M.D,. Santord. NC 

William .V. Hiihharcl. .Ir. \l.l).. Hickory 

Corners, MI 

William F Hulson. Mi),. Noithhrook. II. 

Alexander C. Mitchell. .M.D,. Onehioia. NY 

Sarah T. Momnv. .M.D . PhD,. Raleigh. NC 

S. Malone Parhani. M.D.. Henderson. NC 

Frank R. Reynolds, M.D., Wilminj-ton. N( 

James H. Shell. Jr.. M.D.. Baltimore. Ml) 

Kenneth W. Wilkins, M.D., (ioldsboro, N( 

Kenan B Williams. Ml),. Sanloid. NC 

CLASS OF 1944 
Number in Class: 27 
Percent Donors: 40.7 '> 

J \ incent Arey. M.D.. Concord. NC 

Joseph W. Baggett. M.D.. Fayellevjilc. NC 

Hilda II, Bailey. MO,. Salishury. NC 

.1. Stuart (Jaul. Jr., M.D., ( harlotte, NC 

J, Baylor Henninger. M.I),. Sl.ilesulle. NC 

I laiKis P King, Sr. M.D.. Neu Beiii. NC 

Is.i.ie \ Manlv. MD,. Raleigh. \C 

( harles \. Speas Phillips. M.D.. Southern 

Pines, Nt 

J, Milchell .Soii.iu. Ji,. MD.t hapel Hill. \C 

Charles W. Tillell. Ml).. Charlolle. N( 

J Taylor Vernon, M.I).. Morganlon. .\( 

CLASS OF 1 945 
Number in Class: 24 
Percent Donors: 41.7', 

29 



G. Walker Blair, Jr . M.D.. Burlington. NC 
G. Robert Clutts, M.D., Greensboro. NC 
A. Robert Cordell, M.D., Winston-Salem, NC 

J. Hicks Corey. Jr.. M.D.. Chattanooga. TN 
Courtney D. Egerton. Jr.. M.D.. Asheville. NC 
Grafton C. Fanney. Jr.. M.D-. Bonita Springs. FL 
Harold L. Godwin. .M.D.. Fayetteville, NC 
Ben M. Gold. M.D.. Rocky Mount. NC 
Kuhy T. Hart. Jr.. M.D,. Petersburg. VA 
Edward R. Hipp. Jr., M.D.. Charlotte, NC 
Weldon H. Jordan. M.D.. Fayetteville, NC 
David Josephs. M.D.. Baltimore. MD 
John H. Monroe, M.D., Winston-Salem, NC 
John R. Pender 111. M.D.. Charlotte. NC 
Roger A. Smith 111. M.D.. San Bemadino. C.A 
Clitton F West. Jr.. M.D.. Chestenown. MD 

CLASS OF 1446 

Number in Class: 27 

Percent Donors: 55.6 '/f 

Ira \. .\brahamson, .In, M.D., Cincinnati. OH 

Jules Anier. M.D.. Den\er. CO 
Walter C. Barnes. Jr.. M.D., Texarkana. TX 
Crowell T. Daniel. Jr.. M.D.. Fayetteville. NC 
William W. Forrest, M.D., Greensboro, NC 
Mary .Mice V. Fox, M.D., Mount Desert, ME 
(;. Denman Hammond. M.D.. Pasadena, C\ 
Robert S. Lacke>, MD,. Charlolte. NC 
William H. Sheely. M.D.. Alexandria. VA 
H. Frank Starr, Jr., M.D.. Greensboro. NC 
Da\id G. Stroup. M.D.. Savannah. GA 
Arthur R. Summerlin. Jr., M.D.. Raleigh. NC 
James T. Welbiini. M.D.. Lexington. NC 
John E. Weyher. Jr.. M.D.. Wilmington. NC 
Thomas E. Whitaker IL M.D.. Greenville. SC 

CLASS OF 1^47 
Number in Class: 15 
Percent Donors: 13.3% 

HaiTV G, Walker. M.D.. Statesville. NC 
Sarah L. Waixen. M.D.. Chapel Hill. NC 

CLASS OF 144.S 
Number in Class: 26 
Percent Donors: 34.6% 

Robert R. Aycock. M.D.. Saint Helena. CA 
Vema Y. Barefoot. M.D.. New Bern. NC 
William S. Cheek. Sr.. M.D.. Spartanburg. SC 
T\ndall P Hams. MD . Chapel Hill. NC 
Edwin P. Hiatt. M.D.. Wilmington. OH 
Louis T. Kermon. M.D.. Raleigh. NC 
Julius A. MacKie. Jr. M.D.. Bryn Mawr. PA 
Shirley L. Rivers. M.D., Tucson, AZ 
Daniel T Young, M.D.. Chapel Hill. NC 

CLASS OF 144'» 

Number in Class: 37 

Percent Donors: 32.4% 

J. Dewey Dorsett. Jr.. M.D.. Charlotte. NC 

Christopher C. Pordham III, M.D.. 

Chapel Hill. NC 

John M Ganibill. MD,. Flkin. NC 

K. Sidney (Jardncr. Jr.. M.D.. Fayetteville, NC 

Odell C. Kinibrell. Jr.. M.D.. Raleigh. NC 

Spinks H. Marsh. M.D.. Minneapolis. MN 

Edward B. McKenzie. M.D.. Statesville. NC 

Charles F Melchor. Jr.. M.D.. Myrtle Beach. SC 

Edwin W. Monroe. M.D.. Green\ ille. NC 

Robert B. Pennington. M.D,. Middletown. CT 

Rose Pully. M.D.. Kinston. NC 

30 



Jonathan S. Swift. NLD.. Big Canoe. G.A 

CLASS OF m.so 
Number in Class: 41 
Percent Donors: 70.7% 
Gertrude A. Bales, M.D.. Rochester, NY 
Frederick <), Bowman, Jr., M.D.. Chapel Hill, NC 
W, Grimes B>crl>. Jr. .\1.D,. Hickory. NC 
Jack O, Carson. MD.. Grifton. NC 
Elwood B. Coley, M.D.. Lumberton. NC 
John T. Dees. M.D., Bald Head Island, NC 
Buel K. Grow. Jr.. M.D,. Belle Meade. NJ 
William B. Hams. M.D,. Carlsbad. CA 
Joel B. Huneycutt. M,D.. Lake Wylie. SC 
Harold H, Jeter. Jr.. \LD,. Wilmington. NC 
George Johnson, Jr., M.D., Chapel Hill, NC 
Har\e\ VV, Johnston. M.D.. Charlotte. NC 
William S, Joyner. NLD.. Durham. NC 
John A. Kirkland, M.D.. W ilson. NC 
Laurence B. Leinbach. M.D.. Winston-Salem. NC 
Dan A. Martin. M.D.. Madisonville. KY 
John L. McCain, M.D.. Wilson. NC 
Glenn D. Moak. M.D.. Indianapolis, IN 
James F, Morris. NLD,, Goldshoro. NC 
James H, Pccdin. Jr.. M.D.. Burgaw. NC 
J. Olin Perritt, Jr.. M.D., Wilmington. NC 
John W, Sawyer. M.D.. Wilmington. NC 
Eugene B. Sharpe. M.D,. Asheville. NC 
Lewis S. Thorp. Jr.. M.D.. Rocky Mount. NC 
John F. Trotter. NLD.. Atlanta. GA 
Belk C. Troutman. M.D.. Grifton. NC 
Charles R. Vernon. M.D., Wrightsville. NC 
John L. Waiters. M.D.. Raleigh. NC 
John R, Wilkinson. Jr.. MD.. Hickory. NC 

CLASS OF I4.S1 
Number in Cla.ss: 40 
Percent Donors: 22.5% 

Luther L. Anthony. Jr.. M.D., Gastonia. NC 

John S. Barlow. M.D.. Concord. MA 

W illiam B. BIythe II. M.D.. Chapel Hill. NC 

Baxter 11, ByerK. NLD,. Tallahassee, FL 
A. James Coppridge. NLD,. Durham. NC 
Kari L. Lawing. M.D.. Lincolnton. NC 
Murdoch R. McKeithen. M.D.. Laurinburg. NC 
Luther W. Oehlbeck, Jr.. M.D.. Muse. FL 
John K. Pearson. M.D., Apex. NC 

CLASS OF 19.S2 
Number in Class: 6 
Percent Donors: 33.3% 

Da\ id L. Collins. Jr.. NLD.. Concord. NC 
Charies H. Powell. NLD.. Omiond Beach. FL 

CLASS OF 1454 
Number in Class: 34 
Percent Donors: 47.1% 

Leland S. .■Nverett. Jr.. M.D., High Point. NC 
Paul H. Brigman. M.D.. Trinity. NC 
A. Joseph Diab, M.D., Raleigh, NC 
Malcolm Fleishman, M.D.. Fayetteville. NC 
Charles B. Fulghum. Jr.. NID.. Atlanta. GA 
J. Franklin Graves. NLD,. Mt, Pleasant. SC 
Robert S. Jones. M.D.. Shelby. NC 
James C. Parke. Jr. M.D.. Charlotte. NC 
Cornelius T. Partrick. M.D.. Washington, NC 
Ely J. Perry. Jr.. M.D., Kinston, NC 
Allen Spencer, M.D.. Salisbury. NC 
Nat H. Swann. Jr.. NLD,. Signal Nlountain. TN 
H. Durwood Tvndall. MD,. Goldshoro. NC 



William H. Weinel, Jr., M.D., W ilmington, NC 

Virgil A. Wilson, M.D,. Winston-Saleni, NC 
A. Donald Wolff. M.D., Clemmons, NC 

CLASS OF 1955 
Number in Class: 51 
Percent Donors: 88.2% 
Henry W. Abernethy. M.D.. Hickory, NC 
Harvey Adams. .\LD.. .■Xshehoro. NC 
Julian S. Albergotti. Jr., M.D.. Charlotte, NC 
George W. Barnard. Sr., M.D., Gainesville. FL 
Robert G. Brame, M.D.. Chariotte. NC 
Ralph E. Brooks, Jr.. M.D.. High Point, NC 
E. Ted Chandler. NLD,. Thomasville. NC 
Walter E. Deyton. NLD . Dan\ ille. VA 
Griggs C. Dick.son, M.D., Charlotte, NC 
Presley Z. Dunn. Jr.. MD.. Greensboro. NC 
Charles F. Eddinger. NLD.. Spencer. NC 
John W. Foust, M.D., Charlotte, NC 
John W, Gaines. Jr. NLD.. Newport. NC 
J. Eugene (Jlenn. M.I).. Jacksonville. FL 
Ira D. Godwin, M.D.. Fairfax. VA 
Robert L. Golby. M.D. and Mary B. Golby. M.D.. 
Durham. NC 

James W. Hayes III. M.D.. Burlington. NC 
Charles L. Herring. M.D.. Kinston. NC 
William D. Huffines. NLD.. Chapel Hill. NC 
Vernon 1,. James. Jr.. M.D.. Fair Oaks Ranch. TX 
Samuel G. Jenkins. Jr.. M.D.. Elizabeth City. SC 
Robert C. Jordan. Jr.. M.D.. Sanford. NC 
Samuel B. Joyner. NLD.. Greensboro. NC 
James L, Lamm. NLD.. San Francisco. C.A 
.\. Smith Lineberger. Jr.. M.D.. Wilmington. NC 
William L. London \\. M.D., Durham, NC 
Lloyd C, McCaskill. NLD,. Nlaxlon. NC 
Clarence R. .McLain. Jr.. M.D.. Cincinnati, OH 
Andrew C. Miller III, M.D., Gastonia, NC 
J. Thaddeus Nionroe. Jr. NLD,. Chapel Hill, NC 
Thomas P. Moore. M.D.. Jacksonville. NC 
Frank C. Morrison. Jr., M.D., Canton, NC 
(;. Irvin Richardson, M.D.. Reidsville. NC 
Harold R, Roberts. MD,. Chapel Hill. NC 
OIner K Roddey. Jr. NLD,. Chariotte. NC 
C. W illiam Rogers. M.D.. Lebanon. TN 
William C. RufTm. Jr.. M.D.. Boca (;rande.. FL 
Palmer F Shelbume. M.D.. Greensboro. NC 
Henry L. Stephenson. Jr.. M.D.. Washington, NC 
Robert L. Summerlin. Jr.. M.D.. Dublin, NC 
(;. Reginald Tucker, Jr.. M.D.. Emerald Isle, NC 
W illiam J. Waddell. M.D.. Prospect. KV 
W. Wallace W bite, M.D.. Cincinnati. OH 
William H. While. Jr. NLD.. Gainesville, GA 

CLASS OF 1456 
Number in Class: 50 
Percent Donors: 44.0% 

Wade NL Brannan, NLD.. Port Arthur. TX 
John W, Deyton. Jr.. M.D.. Jacksonville. NC 
William E. Easterling, Jr., M.D., Chapel Hill, NC 
John T. Evans, M.D., Chattanooga. TN 
Charles W. Fowler III, M.D., Oriando. FL 
Alexander F Goley. NLD,. Buriington. NC 
Francis W. Green. NLD,. Albemarie. NC 
John L, Ha/lehursi 111. M.D,. Asheville. NC 
Otis NL Lowry. NLD,. Spnng Hope. NC 
William W. McLendon. M.D.. Chapel Hill. NC 
J, Doyle NIedders. NLD,. Raleigh. NC 
Robert L. Murray, M.D.. Roanoke, VA 
John W, Ormand. Jr. NLD,. Wilmington. NC 
Chflon G, Pavne. NLD,. Reidsville. NC 



Francis D. Pepper. Jr.. M.D.. \yinsroii-Salem. \C 
William R. Purcell. M.D.. Laurinburg. NC 

James F Richards. Jr.. M D . Orlando. FL 
Thomas C. Suther. Jr.. .\I D.. Jackson Springs. NC 
John W Vasse\. M D . Raleigh. NC 
William B. Wood. M.D.. Chapel Hill. NC 

Leonard S. Woodall. M.D,. PA.. Smithfield. NC 
De\ve\ H. Yarley. M.D.. Durham. NC 

CL.ASSOF \9^' 

Number in Class: 50 

Percent Donors: 44.0 '> 

H. John Bradley. Jr.. .M.D.. Greensboro. NC 

Jame^ R Clapp. M.D . Durham. NC 

Robert S. Cline. M.D.. Sanford. NC 

Luther H. Clontz. M.D.. Morganton. NC 

William P. Cornell. .\1.D.. Phoeni\. .A.Z 

George S. Edwards. Sr . M D . Raleigh. NC 

John K. Farringion. M.D.. High Point. NC 

J Grayson Hall. .\I.D.. Mount .Airy. NC 

Bennett .A. Hayes. Jr.. M.D.. Fayetteville. NC 

Jack B. Hobson. M.D.. Charlotte. NC 

J. Paul Hurst. Jr. M.D . Rydal. P.A, 

George L. Irvin III. M.D.. Coral Gables. FL 

Richard \. Liles. Jr.. M.D.. Albemarle. NC 

H. Mixwell .Momson. Jr. .M.D.. Southern Pines. NC 

Har\ey A. Page. M.D.. Pikeville. K\ 

Raeford T. Pugh. M.D.. Washington. NC 

James N. Slade. M.D.. Edenton. .NC 

Nathaniel L. Sparrow. .M.D.. Raleigh. NC 

James H. M. Thorp. M.D.. Rocky Mount. NC 

Earl P. Welch. Jr.. M.D.. W inston-Salem. NC 

Roben J. Whitlock. M D . Easton. MD 

Dr. Benson R. and Mrs. Luclnda Holderness 

W ilcox. Chapel Hill. NC 

CLASS OF 1958 
Number in Class: 50 
Percent Donors: 38.0^f 
James T Alley. .M.D.. .Macon. GA 
Clarence \. Bailey. Jr. M.D.. Durham, NC 
John I. Brooks. Jr.. M.D.. Tarboro. NC 
.Maurice L. Canaday. M.D.. Lincolnton. NC 
M. Paul Capp. M.D.. Tucson. AZ 
David B. Crosland. M.D.. Mt. Pleasant. NC 
James R Edwards. M D . Raleigh. NC 
George E. Ennis. NLD.. Hickory. NC 
Nancy P. Favvcett, M.D., Pembroke Pines. FL 
Thomas VL Haizlip. .M.D.. Raleigh. NC 
John S. Howie. M.D.. Raleigh. NC 
Waller N. Long. Jr.. M.D.. Taylorsville. NC 
Charles T. .Macy. .M.D . Lansdale. PA 
John A. McGee. Jr . .M D . Charlotte. NC 
Luther S. Nelson. M.D.. Amarillo. TX 
T Lane Orniand. M.D.. Monroe. NC 
J. Richard Patterson. .M.D.. Danville. \ A 
Charles W. Stout. M.D.. Asheboro. NC 
Paul .M. Weeks. M.D.. Chapel Hill. NC 

CLASS OF 14.59 

Number in Class: 48 

Percent Donors: 41.7'^r 

Doris B. Braxton. M.I).. Burlington. N( 

Robert C. Brown. M.D.. ( hapel Hill. NC 

Daniel Whilaker D.ivix. Ml). Wadesboro. NC 

A. Eugene Douglas. Jr. Ml). Hald Hcid Island. NC 

Otis N. Fisher. Jr. M.D.. (;reenshoro. NC 

Cieorge W. (;entry. Jr. M.I).. Roxboro. NC 

Joel S. Ciimduin. M.I).. Salisbury. NC 

Robert 1.. (Jreen. Sr.. M.I).. Winslon-Sakin. N( 



O. James Hart. Jr.. M.D.. Mocksville. NC 

.■\. Tyson Jennette. .MD.. Wilson. NC 
Morris A. Jones. Jr.. M.D.. Chapel Hill. NC 
David L. Kelly. Jr.. M.D.. Winston-Salem. NC 
Roben P Linker. M.D . Charleston. SC 
Wilfred D. Little. Jr.. M.D., Ana Mana. FL 
Edward L. Mitchell. M.D.. Prospect. KV 
A. Sherman Morris. Jr.. M.D.. Ashevlllc. NC 
Julian W. Sclig. Jr.. M.D.. Eli/ahcth City. NC 
Shahane R. Taylor. Jr.. M.D.. Cireensboro. NC 
Charles E. Trado. Jr.. M.D.. Hickory. NC 
C. Carl Warren. Jr.. M.D.. Charlotte, NC 

CLASS OF l%0 

Number in Class: 63 

Percent Donors: 60.3'! 

\\ illiam B. Abernethy. Jr.. M.D., Gastonia, NC 

Leo R Anderson. M.D.. Corona Del NLir. CA 
Ralph L. Bentley. M.D.. Statesville. NC 
James A. Campbell. M.D.. Charlotte. NC 
John R. Curtis. M.D.. Athens. GA 
John R. Dykers. Jr.. .M.D.. Siler City. NC 
Charles R Eldndge. Jr.. M.D.. Houston. T.\ 
Gerald W, Femald. M.D,. Chapel Hill. NC 
Charles E. Fitzgerald. Jr.. .M.D.. Maitland. FL 
J. Thomas Fox, Jr.. M.D.. \allc Crucis, NC 
David B. Garmise. M.D.. Blumon, SC 
Roben H. Hackler 111. M.D.. Richmond. VA 
James R. Harper. M.D.. Durham. NC 
Ch.irles W, H.irns. M.D . Ch.irloite. NC 
Falls L. Harris. M.D.. Cireenville. SC 
G. Wyckliffe Hoffler. M.D.. Titusville. FL 
L. Gordon Kirschner. M.D . Washington. DC 

E. Carwile LeRoy. M.D.. Charleston. SC 
James Ci. Mann. M.D.. C;olden. CO 
James M. Marlowe. NLD.. High Point. NC 
J. Gr.iy McAllister III. Ml). Chapel Hill. NC 

K. Franklin McCain. M.D.. W inston-Salcm, NC 
William N, Michal. Jr.. .MD,. High Point. NC 
Cecil H. Neville. Jr. M.D.. Pinehurst. NC 
Duncan S. Owen. Jr.. M.D.. Richmond. \ A 
Robert B. Payne. M.D.. Mooresville. NC 
Jerry M. Petty. M.D.. Charlotte. NC 
Jean R Poinei, Ml) . Frederick. MD 
Elizabeth \. Raft. NLD.. Durham. NC 
Charles W, Robinson III. M.D.. San Antonio. T\ 
Hilliard F Seigler, M.D., Durham. NC 
Robert F Sloop. Jr.. .M.D.. Wilson. NC 
Elliott .Solomon. M.D.. Rye Brook. N^ 
G Thomas Strickland. Jr.. M.D.. Baltimore. MD 
John C. Tayloe. M.D.. New Bern. NC 
P Bun Vea/ey. .M.D.. Sarasota. FL 
Kenneth Weaver. M.D.. Jonesborough. TN 
John J. White. Jr.. M.D.. Winston-Salem. NC 

CLASS OF 1461 
Number in Class: 50 
Percent Donors: 52.0'f 

F. Stanley .\\ci>. Jr. .Ml),. Noilolk. \,\ 
H. David Bruton. M.D.. Carthage. NC 
Cosmo A. Dita/io. M.D.. Ph.D.. C1iarlottes\ ille. \A 
John W. Garden. NLD.. Lexington. KV 

W illiam S. Gibson, Jr., M.D.. Riverside, PA 
John C Graham, Jr, .M D,. Kitty Hawk. .NC 
L Morgan Hale. M.D . Ch.ipel Hill. NC 
Richard W Hudson. NLD , BaNb<iro, NC 
William H. Koun. M.D.. Isle of Palms. SC 
/ell A .McGec, M.D., Salt Lake City. IT 
U. Stacy Miller. M.D.. Raleigh. NC 
William W Mor.jan. Jr. M I) . Keno. W 



.•\ Ray Newsome. M D . Winston-Salem. NC 

C. Rex O'Briant. M.D.. Gilbert. AZ 

William L Owens. M.D . Clinton, NC 
Cecil H. Rand. Jr.. M.D,, Greenville. NC 
Leon;ird E. Reaves 111. M.D., South Brunswick. NC 
James H. Robinson. M.D.. Wilmington. NC 
W. Ray Samuels. M.D.. Kiawah Island. SC 
Edward .\. Sharpless. M.D. and Martha K. 
Sharpless. M.D.. CJreensboro. NC 
W Fenell Shutoid. Ji.. Ml).. Wilminglon. NC 
Joshua Tayloe. M.D.. Washington. NC 
Zebulon Wea\er 111. .M.D . Ashe\ille. NC 
Donn A. Wells. M.D.. .Sea Ranch Lakes, FL 
William H White. Jr. M.D.. Sanford. NC 

CLASS OF 146: 
Number in Class: 52 
Percent Donors: 42.3'^f 
Karl L Barkley. M D.. Greensboro. NC 
William S. Bost. Jr., M.D.. Greenville. NC 
Joseph H. Callicott, Jr, M.D., Lynchburg. V.A 
Lawrence M. Cutchin. M.D.. Tarboro. NC 
Jen-y J. Filer. MD,. Li\ingston. AL 
Marion W, Grift'in. M D,. Asheboro. NC 
Frederick D, Haninck 111. MD . Lynchburg. \A 
H. CJerald Hartzog IH. .M.D.. Raleigh, NC 
Ray M. Hayworlh. M.D.. Knoxville, TS 
Charles M. Hicks. MD.. Wilmington, NC 
J, Neuton .MacCoriiKick. Ml) . Raleigh. NC 
John L. Monroe. M.D.. West End. NC 
Kenny J. Morris, .M.D.. W ilmington, NC 
William A. Nebel. NLD.. Chapel Hill. NC 
W Gordon Peacock. NLD . San Francisco. C.\ 
Carl S. Phipps. M.D.. \Mnston-Salem, NC 
Alton A. Reeder. M.D.. High Point. NC 
Lambros C. Rigas. MD,. Rome, GA 

D, Emerson Scarborough. Jr., NLD.. Raleigh. NC 
Fuller A. Shuford, NLD., Asheville, NC 
Miriam F Smith, M.D., Decatur. GA 

Roy V. Vamer, M.D.. Houston, TX 

CLASS OF 146.^ 
Number in Class: 52 
Percent Donors: 40.4'( 
W illiam P Algary. M.D.. C;reen\ille, SC 
Neil C. Bender. M.D.. New Bern. NC 
W P.iul Riggers. M D . Clupel Hill. NC 
I. Kelman Cohen. NLD.. Richmond, \.\ 
John W, Dallon. Jr.. NLD.. Santa Nlonica. CA 
Da\e NL Da\is. M D . Atlanta. GA 
William B, Deal. NLD,. Bmmngham. AL 
J. Nlichael Gallagher. NLD.. Seattle. \\A 
Ira M. Hardy II. M.D.. Greenville. NC' 
William () Jolly 111. NLD.. Albemarle. NC 
Charles I. Loftin HI, M.D., Roanoke. VA 
J. M. McLean, M.D., Peoria, 11. 
Eugene W. Pate. Jr.. M.D., Kinsion. NC 
Charles J. Sawyer 111. Ml),. Ahoskie. NC 
Samuel E, Scott. NLD.. Burlington. NC 
Richard W. Shermer. M.D.. Chapel Hill. NC 
DaMd W. Sillmon. NLD.. Greensboro, NC^ 
Jen-y A. Smith, NLD., NIemphis. TN 
W. Landis Voigl, M.D , Edenton, NC 
Ro\ A Weaker. Nil). Fa>etle\ ille, NC 
DaMd R Williams. Si . M I),. lhomas\ille. NC 

CLASS OF 1464 

Number in Class: 54 

Percent Donors: 25,'»'< 

J. Nichols Beard. M,l)„ ( harlolle. N( 



Harry L. Broome, M.D., Alpharetta, GA 
John R. Ctlla. M.D.. Raleigh. NC 

Roy L, Curr). Jr.. M.D., .San Francisco. CA 
James F. Earnhardt. M.D.. Winston-Salem. NC 
G. Patrick Henderson. Jr.. M.D.. Southern Pines. NC 
E. Citniiack Holmes. Jr.. M.D.. Pacific Palisades. CA 

D. Charles Hunsinger, M.D., Kin.ston, NC 

E, Woodnnv Hum. Jr.. WD.. La Jolla. CA 

W. Kirhy Kilpatrick. .|r, M.I).. Pinehurst, NC 
Noel B. McDevitt. M.I).. .Southern Pines, NC 
Artus M. Moser, .Jr., M.I)., .Swannannoa, NC 
Marshall K. Redding, .M.I)., Long Beach, CA 
James W. Rose. Jr.. .M.D.. Madison. Wl 

CLASS OF 1 465 
Nuniher in Class: 57 
Percent Donors: 42.1% 

G. William Bates. M.D.. Brentwood. TN 
Hal F Collier. M.D.. Flowery Branch. GA 
Takey Crist, M.D., Jacksonville, NC 
Robert \. Fulk. Jr.. Ml).. Wilnimgton. NC 
Kdgar (;. (Jallagher, Jr.. M.I).. Jacksonville, NC 
Mar\iii R. Cloldsiem. M.I).. Scollsdalc. .\Z 
Rohert I,. (Jrubh, Jr., .M.D., (Jlendale, MO 
Joe W, Hardison. M.D., Fayetteville. NC 
Alexander C. Hattaway 111. M.D., Raleigh. NC 
Das id C. Hcleltlnger. M.D.. Tuscaloosa. AL 
Howard Holderness. Jr., M.D.. Greensboro. NC 
.loe P Hurt. M.D., Ph.D., .Sylva, NC 
Bcrn.ird R J.ick. .Ml).. A/le. T,\ 
Rohert I. Kindley, M.D., Mary Esther, FL 
RiclKird H. Lassiier. M.D.. Chapel Hill. NC 
(Jordon B. LeCJrand, M.D., Raleigh, NC 
Sue E. Massey. M.D.. Scotts Valley. CA 
William D. McLesler. M.D.. Ph.D.. Fayette\ ille. NC 
Donald D. McNeill. Jr.. M.D.. Lenoir. NC 
l.leuellyn Phillips II, M.D., Renton. WA 
Thomas L. Presson. M.D.. Greensboro. NC 
William F. Sayers, M.D., Winston-Salem, NC 
Evin H, Sides 111. M.D.. Raleigh. NC 
Wilhs H, Williams. Ml).. Atlanta. GA 

CLASS Ol- h)(i(i 
Number in Class: 63 
Percent Donors: 49.2% 
J. Curtis Abell. M.D., .Statesville. NC 
Robert P Bamnger. M.D.. Gastonia. NC 
Rohert H. Bilhro. M.D.. Raleigh, NC 
Tmiotin i:. C'loningcr. Ml),. Charlotte. NC 
(Jeorge W. t (>\, M.D.. Atlanta, GA 
William M. t rutchfleld. M.D.. Elizabeth City, NC 
Philip C. Deaton. M.D.. Greensboro. NC 
Kdgar C. (Jarrabrant II. M.D.. Raleigh, NC 
Robert C. (;ibson III, M.D.. Portland, OR 
Carol H. Hacketl. Ml),. Mercer Island. WA 
Law rence I). Henry, M.I).. Jefferson City. MO 
Howard T Hinshau. MI).. Ch.irlotte. NC 
N, Neil Howell. Ml),. Charlotte. NC 
William C. Hubbard, M.D.. Raleigh, NC 
Hugh A. McAllister. Jr.. M.I).. Houston. T\ 
Kdgar M. McCiec. M.D.. Lexington, KV 
Duncan Morton. Jr.. M.D,. Charlotte. NC 
Hugh (;. Murray, Jr., M.D., Atlanta, GA 
R. Kenneth Pons. M.D., Medtord, OR 
James A. Pressly. M.D.. Charlotte. NC 
Surry R Roberts. M.D.. Raleigh, NC 
Charles K Scott, M,D,, Haw River, NC 
Robert K. Sevier, M.D., tireensboro, NC 
J. Lewis Sigmon, Jr., M.D., Davidson, NC 
H Lee Smyre, M.D., Greer. SC 

^2 



E. Walker Stevens. Jr.. M,D.. Greensboro. NC 
W. Beverly Tucker III. M.D.. Henderson. NC 
W. Hunter Vaughan, M.D., Steubenville, OH 
James H. Whicker. M.D.. Raleigh. NC 
John A. Young, M.D., Charlotte, NC 
James A. \ount. M.D.. Charlotte. NC 

CLASS OF 1967 

Number in Class: 67 

Percent Donors: 46.3% 

F Walton A\ery. M.D.. Chapel Hill. NC 

Rudy W. Barker. M.D., Durham. NC 

Gerald W, Bl.ikc. .M.D,. Raleigh. NC 

Thomas \\. Bundy. M.D.. Chambersburg. P\ 

Joseph M. Cr.uer. M.D.. Atlanta. GA 

Vartan .A. Davidian, Jr., M.D., Raleigh, NC 

Da\id .-X. Evans. M.D.. Monroe, NC 

R. Donald Garrison, M.D., Jacksonville, FL 

Harvey J. Hamrick, M.D.. Chapel Hill. NC 

K. Franklin Hart. Jr., M.D., Morganton. NC 

L. Fuller lIone>cutl. Jr.. .\1,D . Raleigh. NC 

James I). Hundley, M.D., Wilmington, NC 

Scott (;. Kleiman. M.D.. Marietta. GA 

Frank W. Leak. Sr.. M.D.. Clinton. NC 

Hugh T. LetJer. Jr.. M.D. and Constance Farthing 

Letler. Ph.D. Fori Worth. TX 

Robert W. Madry. Jr., M.D., Corpus Christi, 

TX 

W. Jason McDaniel. Jr.. .M.D., Raleigh, NC 

Joseph T. Mcl.anih. Ml),. Goldsboro. NC 

Donald H. McQueen III. M.D.. Rock Hill. SC 

Rudolph I. Mint/. Jr.. .M.D.. Kinston, NC 

Harold B. Owens. M.D.. Danville. VA 

II Richard Parker, Jr.. .M.D.. Greensboro. NC 

(ierald Pelletier. Jr.. M.D.. New Bern, NC 

Albert L. Roper II. M.D.. Norfolk, VA 

Douglas M. Russell. M.D.. Goldsboro, NC 

Walter R. Sahiston. M.D.. Kinston. NC 

James H. Spruill, M.D,. Jackson. TN 

Henry I'. Thomason. Jr.. M.D.. (Jastonia, NC 

Benjamin K. Ward. Jr.. M.D.. Florence, SC 

Barry M. Welborne. M.D.. Charlotte. NC 

CLASS OF l%X 
Number in Class: 62 
Percent Donors: 43.5% 
Joseph P. Archie, ,Ir.. M.D.. Raleigh, NC 
George W. Bensch. M.I),. Stockton. CA 
Lucius Blanchard. Jr.. M.D.. Las \egas, N\ 
Edward W, DaMdi.m, .M.D . Ch.ipel Hill. NC 
Alan Davidson HI, M.D., (Jreensboro, NC 
Ten-\ D. Golden. M.D.. Atlanta. GA 
Theodora L. Gongaware. M.D.. Savannah. GA 
Joseph \V. Griffin, Jr.. M.D.. Augusta. GA 
W, F Hancock. Jr.. M.D.. Burlington. NC 
Hoke F Henderson. Jr.. M.D.. Columbia, SC 
John L. Kirkland 111. M.D.. Houston, TX 
Edward W. Kouri, M.D.. Charlotte. NC 
Jerold E. Lancourt. M.D.. Dallas. TX 
Paliick T. Malone. M.D.. Rosuell. GA 
Robert G. Martin, M.D., Southern Pines. NC 
Rulhertoid B. Polhill. Jr.. M.D.. Birmingham. AL 
David M. Rubin. M.D.. Greensboro. NC 
Carole \\. Samuelson. M.D.. Birmingham. ,\L 
E. Franklin Shavender. M.D.. Durham. NC 
Robert B. Sheann. M.D.. Rockville, MD 
Valerie L, Slallings, M.D.. Norfolk. VA 
George S. Stretcher. M.D.. Spartanburg. SC 
William S. Teachey. M.D.. Virginia Beach. VA 
Robert C. Vanderben^. Jr.. M.D.. Raleiah, NC 



Jerry C. Woodard, M.D., Wilson, NC 

Richard H. Wra\ III, M.D., Morehead City. NC 
Stephen W. ^oung. M.D., Austin, TX 

CLASS OF 1969 

Number in Class: 64 

Percent Donors: 37.5% 

P. Kugene Brown, M.D., Hickory, NC 

J. Hugh Bryan, M.D., Fayetteville, NC 

W. Woodrim Burns. Jr.. M.D.. Chapel Hill. NC 

Don C. Chaplin, M.D., Burlington, NC 

R. Samuel Crom.irtie 111. M.D.. Omiand Beach, FL 

Hugh J. Grant. Jr.. M.D., Raleigh. NC 

G Patrick Guiteras. .M.D.. Chapel Hill, NC 

Edward W. Haseldcn. Jr., M.D., Columbia, SC 

J Thomas John, Jr.. M.D.. Nashxille. TN 

Dr. and Mrs. W illiam R. Jordan, Fayetteville. NC 

Richaid A. Keever. M.D.. High Point. NC 

Edward H. Lesesne. Jr., M.D., Canton, NC 

C. Clement Lucas. Jr.. M.D.. Larchmont. N^l' 

Henry J. MacDonald. Jr.. M.D.. New Bern. NC 

R. James MacNaughton, Jr., M.D., (ireenville, SC 

David W, Peaisall. Jr.. M.D.. Greenville. NC 

James S. Powers. M.D.. Bethesda. MD 

Joseph D. Russell, M.D.. Wilson, NC 

David S. Sheps. M.D.. Gainesville. FL 

James W. Snyder. M.I).. W ilmington. NC 

Karen C. .Sorrels. M.D,. Midlothian. \ A 

Franklin T Teu, Ml),. Chapel Hill. NC 

John t . Triplett. M.D.. M.P.H.. Bethesda. MD 

Nelson B. Watts. M.D.. Atlanta, GA 

CLASS OF 1970 
Number in Cla.ss: 70 
Percent Donors: 61.4% 

H. Chlford Baggett, Jr., M.D., Rocky Mount, NC 

Jerry C. Bernstein, M.D., Raleigh, NC 

Robert G. Blair. Jr. M.D. and Pauline M. Blair. 

MI). New Bern. NC 

William J. Busby. M.D.. Thomasville. NC 

William K. Byrd. M.D.. Roanoke Rapids, NC 

Harold H. Cameron. M.D.. New Bern. NC 

Daniel L. Crocker. Jr., M.D.. Rocky Mount, NC 

Ch.irles E. Crumley. M.D.. Lincolnton. NC 

H. Shelton Karp HI, M.D. and Joanne Karp. 

Ph.D., Chapel Hill, NC 

Mary H. Edwards. M.D. and David J. Edwards. 

PhD,. Pittsburgh. PA 

Richard M. Freeman. M.D.. Opelika. AL 

James O. (ioodwin. M.D,. Henderson. NC 

John F. Hanna. M.D.. Sarasota. FL 

Joseph M. Harmon. M.D.. Mount Pleasant, SC 

John K Ilartness, Jr.. M.D.. Monroe. NC 

W. Borden Hooks. Jr., M.D., Mount Airy, NC 

Donald 1). Howe. M.D,. Gastoni.i. NC 

Dr. and Mrs. Mark G. Janis. Seal Beach, CA 

James J Jenkins. M.D.. Saint Louis. MO 

V. Bryan Koon. Jr.. M.D.. Durham. NC 

Frederick (i. Kroncke. Jr., M.D., Rocky 

Mount, NC 

John R. Leonard 111. .M.D.. Greenville. NC 

James D. Melton. M.D.. Morganton. NC 

Michael A. Moore. M.D., Danville, VA 

Edward A. Nortleet. M.D.. Chapel Hill, NC 

L. Christine Oliver, M.D., Brookline, MA 

Hoke Pollock. M.D.. Wilmington. NC 

R Kirhy Primm, .M.D . Wenatchee. WA 

David A. Rendleman HI, M.D., Raleigh. NC 

Thomas A. Roberts, Jr„ M.D., Charlotte, NC 

Subir Rov, M,D., Pasadena, CA 



A. Stevens Rubin. Jr.. M D . Chatsworth. C.A 
James B. Sloan, M.D., Wilmington, NC 
Kenneth W. Sniithson. .\!.D.. Inins;. T\ 
Jame>. D. Smithwick. M-D.. LaurMiburg. NC 
Charle-s E. Thompson, .M.D., New Rochelle, W 
T. Reed I nderhill. M.I).. NeH Bern. NC 
Ross L. \aughan. M.I).. Raleigh. NC 

E. Lance Walker. M.I).. Littklon. fO 
William ,|. Weatherlj. M.I)., (ireenshoro. NC 
H. Grev Wintield 111. .\1.D.. llickon. NC 

CLASS OF 1471 

Number in Class: 73 

Percent Donors: 24.7 'r 

Robert A. Bashford, M.D.. Chapel Hill. NC 

J,imes S. Co\e 111. .\1.D . Ralcii:h. NC 
James S. Fulghum III. M.I), and Mar) Susan 
Fulghum. .M.I)., Raleigh. NC 
Joe E Gadd>. Jr . M.D.. W inston-Saleni. NC 
Daniel P. Greenfield. M.D.. Short HilK. NJ 
Michael R. Knowles, M.D.. Chapel Hill. NC 
Kathnn R. Ku\kendal. Cineinnati. OH 
Richard A. Nelson. M.D.. Cordo\a. TN 
Frederick S. Neuer, .M.D., Emporia, KS 
William B. Piltman, M.D.. Rock> Mount. NC 
R. R.indolph P.mell. .\1.D.. Ho\ Point. \VI 
Charles H. Richman. M.D.. Saratoga Springs. N"^ 
Virgil O Roberson 111. M.D.. High Point. NC 
J. Allison Shivers. M.D., Asheville, NC 
Sara H Sin.il. Ml). W insion-Saleni. NC 
John P. Surratt. M.l).. Clinton, NC 
George C. \enters, M.D., Raleigh, NC 
David K Wagoner. M D.. Charlotte. NC 

CLASS OF 14"; 

Number in Class: 70 

Percent Donors: 37.1 "^^ 

Henrv H Atkins 11. .\1.D.. Hampden. ME 

Robert L. Barnes 111. M.D.. Knoxville. TN 

Myron H Brand. M.D.. .Madison. CT 

Peter R. Bream, M.D., Jacksonville, FL 

L. Franklin Cashuell. Jr.. M.D.. Greensboro. NC 

Randolph B. Cooke. M,D.. Owego. N't 

Cecil M. Famngton. Jr.. M.D.. Salisburv. NC 

Karen W. Green. M.D . Holden. .\IA 

Alger \'. Hamrick 111. M D . Raleigh. NC 

L. Clayton Harrell III. M.D.. Charlotte, NC 

Hubert B. Hasuood 111 .Ml) . Raleigh. NC 

F. Christian Heaton. M.l).. Raleigh, NC 
Larrv A High. Jr . .\1 L).. Rockv Mount. NC 
Wilham B Horn. .M.D . Boone. NC 

John S. Hughes, M.D.. .New Haven. CT 
Thomas G. Irons. .M.D.. Greenville. NC 
Joseph A. Jackson. M.D.. Pilot .Mountain. NC 
Howard S. Kroop. M.I).. Woodbury. NJ 
William \. Long. Ml). Ne«lnn. N( 
John R. Lurain III, M.D.. Oak Park, IL 
John T .Manning. Jr.. M.D,. Houston. TX 
John R. Partridge. M.D.. .Midlothian. VA 
lames S. Reed, M.D., (;ig Harbor. WA 
I I ledenck Wolfe. M D.. Knovsillc. IN 
J Kieh.ird Young. .Ml).. Sherborn. MA 

CLASS OL 147 < 

Number in Class: 81 

Percent Donors: 35.8 'i 

Frederic F. Bahnson 111. M.D.. Brevard. NC 

Ci RutTin Benton 111. .VI. D.. Brevard. NC 

Stephen A Bernard. .M.D.. Chapel Hill. NC 

Stephen B. Billick. .M.D.. New York. NY 



Jesse A. Blackman. M.D.. PA.. Fremont, NC 
Thomas B. Cannon. M.D.. Winston-Salem. NC 
Nad\ M Gates 111. .\I D . Chapel Hill. NC 
Franklin S. Clark III. M.D.. Kayetteville. NC 
LKnd K. Conistoek. M.D.. Snow Camp. NC 
Frank E. Davis HI. M.D.. Roanoke Rapids. NC 
John E. Estes. Jr.. M.D.. Rocky Mount, NC 
L, Rultni Franklin. Jr.. M.D.. Raleigh. NC 
J. Blake Goslen 111. M.D., Charlotte. NC 
David A. (Jrimes. .M.D.. Chapel Hill, NC 
J Michael Harper. M.D.. Charlotte. NC 
F Daniel Jackson. M.D.. Cumberland. MD 
E. Earl Jenkins. Jr.. M.D.. Rock Hill. SC 
J. t harles Jennette. M.l).. I hapel Hill. NC 
Dennis R Johnson. .\1 D . ^ork. PA 
Colin D Jones. .M D . Ahoskie. NC 
James L. Maynard, M.D., Rock Hill, SC 
Dale A. Newton. M.D.. Green\ille. NC 
David R. Patterson, M.D., Greensboro, NC 
W. McLean Reavis. Jr.. M.D.. Lakeland. FL 
Da\ id E. Sharp. M.D.. Ph.D.. Bear Creek. PA 
S. Wa>ne Smith. M.D.. Raleigh. NC 
George H, Lnderwood. Jr.. M.D., Honolulu. HI 
Robert R. Walthtr, M.D.. New York, NY 
William H, Whisnant. M D.. Bristol. TN 

CLASS OF 1474 

Number in Class: 97 

Percent Donors: 33.0'> 

Robert M. Alsup. M.D., Winston-Salem, NC 

Thomas W. Bouldin. M.D.. Chapel Hill. NC 
W. Gnft'lth Bowen. M.D., St. Louis. MO 
Douglas C. Brewer. M.D.. Elm City. NC 
Donald C. Brown. M.D.. Can. NC 
David R. Clemmons, M,D., Chapel Hill. NC 
Thomas H. Dukes 111. M D.. Charleston. SC 
Donna E. Fnck. .M.D.. Chapel Hill. NC 
Stephen S. Hawkins. M.D.. Hixson. TN 
C. Norman Hurwii/. M.D.. Fairfield. Oil 
Joseph M. Jenkins, M.D., Fayetteville, NC 
Stephanie L. Kodack, .M.D., .Austin, TX 
John A. Lang 111. M.D.. Raleigh. NC 
Clarence E, Lloyd. Jr.. MD.. Greensboro. NC 
Sheppard A. McKenzie III, M.D., Raleigh. NC 
Cl\de Nolan. Jr.. M D.. Greensboro. NC 
II. Clill(m Patterson III. M.l).. Raleigh. NC 
Harold C . Pollard III. M.l).. Winston-Salem. NC 
C. Eredric Reid, M.D.. W inston-Salem. Nl' 
Su/anne V. Sauter. .VI. D.. Chapel Hill. NC 
Charles W. Smith. Jr.. M.D.. Little Rock. \R 
Roger L. Snow. VI. D.. Boston. VIA 
Da\id E Tart. VI D. Hickorv. NC 
David T. Tayloe, Jr., M.D., Goldsboro, NC 
John W. Thornton 111. VLD.. Augusta. GA 
Larry E. WaiTcn. M.D.. Chapel Hill. NC 
Charles H. Weiss. M.D.. Newton. MA 
Kenneth H. Wilson. VLD.. Chapel Hill. NC 
William G. Wilson. VLD . t harloiiesvillc. VA 
Heishel L. Wi\. Jr.. .VLD.. VI. nice. IL 
Charles I), ^bder. VLD.. FairMcw. NC 
I). Bryan Young. M.D.. Shelby. NC 

CLASS OF I47.S 

Number in Class: Mlfi 

IVrccnl Donors: Ai).<,' , 

I., .lackson Allison. .|r.. VI. I)., last Syracuse. N^ 

Bruce A. Bellow. VI 1). Vlsslic. ( I 
William J. Blacklev. VI. D.. KIkin, N( 

Julian CBunllev 111. VI I) . Rock\ Vloum. N( 
Julian T Branllev. Ji . VI I) . Vienna. \ A 



Patrick G. Bray. M.D.. Shaker Heights. OH 
Samuel L. Bridgers II. M.D., Woodhridge, CT 

E. Drew Bridges. VLD.. Wake Forest. NC 
Cvril S. Dodge. M.D.. Vancouver. WA 
Benjamin Douglas. VLD.. Dillsboro. NC 
William H. Edw.iids. VI D and Susan T 
Edwards, M.D-. Norwich. \T 
Clarence E, Foglem.ui 111. M I). 
Colorado Springs. CO 
Richard F. Fox. VI. I).. Cireensboro. NC 
Donald C;. Ciregg, M.D.. CJreenville, SC 
Eric H. Hels.ibeck. VLD . Asheboro. NC 
Ernest E Krug III. VI. I).. Rochester. MI 
C harles P. I.anglev III. VI. 1).. Shelby, NC 
David S. I.ennon. VI. I).. C harlotte, NC 
Howard A. VIcVlahan. VI. I).. Vlarietia, (iA 
Frank 11. VIoiet/. VLD.. .\shc\illc. NC 
Wade H VIoser. Jr.. VLD.. Raleigh. NC 
Dan A. Myers, M.D.. Kinston, NC 
]\. Ronald .\eal, M.D., Greensboro, SC 
Henry N Nelson 111. VLD.. Indialantic. FL 
Lanning R, Newell. VLD.. Raleigh. NC 
Vlaishall ILOdoin. M.I). Boone. NC 
Stephen L. Okiye, M.D., Saint Thomas, \ I 
Henrv E. Parfiti. Jr.. VI. D.. Fayetteville. NC 
H. Worth Parker. M.D., Norwich, VT 
Jerry E. Patterson. M.D., Chapel Hill. NC 
James E. Peacock. Jr.. VLD.. Winston-Saleni. NC 
Claudia A. Peters. VLD.. Kingston. ON 
Joseph B Philips 111. VI I),. Birmingham. AL 
Hoke D. Pollock, Vl.D., W ilmington, NC 
James L. Price 111. M.D., Wilmington. NC 
Joseph R. Pringle. Jr.. M.D., Burlington. NC 
W. Paul Sawyer. M.D.. Tallahassee. FL 
Michael A. Stang. M.D.. Pikesv ille, MD 
Kenneth K. Steinweg. VLD . Greenville. NC 
Carol B. Teutsch. VLD.. Gwvnedd \allev. PA 
James W, Winslow. VLD.. Tarboro. NC 
Kenneth II. W inter. VI. I)., (ireenshoro. NC 

CLASS OF 147(1 
Number in Class: 12(1 
Percent Donors: 3(1.0 '-f 

Bienda L Adams Hudson. VLD.. VIooie. SC 

Warwick Aiken III. VLD. and Janet Cyhiynski 

Aiken. VLD.. Gastoma. NC 

Paul D. Barry. M.D.. CJreensboro, NC 

Vlartin F Beals. Jr.. VI D . Bluefield. \ A 

Jean C. Bolan. M.D.. Washington. DC 

AlevisC BoutenetL VI. 1).. Litchfield. CI 

Rich.ird A Bowerman. VLD . Ann Arbor. VII 

Barbara J. Campbell. Vl.D.. Somerset. PA 

Vlariorie B. Can. Vl.D.. Raleigh. NC 

F^dward I.. Cattau, Jr.. Vl.D.. (Jernianlown. IN 

William II. (iamble. Vl.D.. (ireensboro, NC 

( harles II. Hicks, Vl.D.. W ilmington. NC 

J. Lee llollci. Vl.l). leiiiplc. I .\ 

Robert H. Hulchins. M.D.. Wilmington. NC 

Walker A. Long. .VLD.. Ch.ipel Hill. NC 

Ross I) Lvnch. VI I) . ColiiinhLi, S( ' 

VlcKav VkKmnon. VI I) . Kciiiluoiih. II. 

Michael \: Vlillei. VLD. Iiaiiklm. IN 

B Douglas VIorton III. VI 1) . Vlacon. GA 

Robert S. VIoskalik. VI 1) . Coldwatei. Vll 

E. Paul Nance. Jr., M.D.. Nashville. TN 

I. Andrew Nassel. Jr. VI I) . Danville. PA 

David B. Neeland. Vl.D.. VIontgomery. AL 

ll.irokl A Nichols. VLD . Giecnsboro. NC 

Kathleen (iallagberOxner. M.l).. (ireenv ille. SC 

Sheldon VI, Rclchin. VI I). Richmoiul, \ \ 



Tamara L. Sanderson, M.D., Lexington, KV 

Robert S. Shapiro. M.D.. Athens. GA 
David F. Silver. M.D.. Charlottesville. VA 
Robert J. Tallaksen. .M.D., Morgantown, WV 
R. Henry Temple. Jr.. M.D,. Wilmington. NC 
F. Ray Thigpen, M.D., Whiteville, NC 
Mark E. Williams. M.D.. Charlottesville. VA 
Riehard L. Wing. M.D.. Charlotte. NC 
Sabra A. VVoodard, M.D.. Raleigh, NC 

CLASS OF 1977 
Number in Class: 119 
Percent Donors: 24.4 9} 

.Michael L, Ban-inger. M.D.. Shelby. NC 

.lohii R. Black. M.D.. Zionsville. IN 

Clinton A. Bnlev. Jr. M.D.. Wnghtsvillc Beach. NC 

Francis S. Collins, M.D., Ph.D.. Rockville, MD 

Joseph E. Craft. M.D.. Guilford. CT 

Allen J. Daugird. M.D.. Chapel Hill. NC 

Meyer E. Dworsky, M.D., Huntsville, .\L 

Wayne D. Fogle. M.D.. Knowille. TN 

Peter C. Gruenberg. M.D.. .^Itamonte Springs. FL 

Charles H. Hoover. III. M.D.. Monroe, NC 

William L. Isley. M.D.. Kansas City. MO 

L. Lyndon Key. Jr.. M.D. and Janice D. Key. 

M,D.. Hollywood. SC 

Judith M, Kramer. M.D.. Chapel Hill. NC 

Frederick 11 Mahry. Jr. MD.. Lanrinhurg. NC 

•Stephen Ray .Mitchell, M.D., Alexandria, VA 

Warren H. Moore, M.D., Sugar Land, TX 

H. Grady Morgan. Jr.. M.D.. Wilmington. NC 

Pamela A. Nel.son. M.D.. Raleigh. NC 

Scott H. Norwood. M.D.. Tyler. TX 

Louis M. Perlniutt, M.D., Chapel Hill, NC 

Michael L. Pool. M.D.. Knowille. TN 

Duncan S. Postma. M.D.. Tallahassee. FL 

Catherine M. Radovich. M.D.. Gallup. NM 

Samuel T Selden. M.D.. Chesapeake. VA 

Howard J. Stang. M.D.. Stillwater. MN 

.lohn H. Stanley, Jr., M.D., Wilmington, NC 

Michael M. Ward. M.D.. Wilmington. NC 

Richard H, Wcislci. MD,. Raleigh. NC 

CLASS OF l')7S 
Number in Cla.ss: 129 
Percent Donors: 25.6'7f 

T Rupert Ainsley. Jr.. M.D,. Sanford, NC 
Michael C. Alston. M.D,. Murtreesboro. NC 
James J, Bedrick. M.D.. Charlotte. NC 
John D. Benson, M.D., Cary, NC 
Jean W. Carter. M.D.. Raleigh. NC 
Brian J. Cohen. M.D.. Sudbury. MA 
Cvnlhia D Conrad. M D,. PhD,. Branford. CT 
Paul W. Coughlin, M.D., High Point, NC 
Betty J, Crosby. M.D,. Charlotte. NC 
Allison J. Dudley. M.D.. Charlotte. NC 
Martha L. Elks. M.D.. Atlanta. GA 
Seth V. Hetherington. M.D.. Chapel Hill. NC 
Michael D. Holland. M.D.. Rocky Mount. NC 
Cynthia R. Howard. M.D.. Baltimore. MD 
Dorothy M. Linster. M.D.. Raleigh. NC 
Wade L. Lowry. M.D,. Colleyv ille. TX 
Jeftiey A. Margolis. MD.. Tappahannock. VA 
John T. McElvecn, Jr., .M.D.. Raleigh. NC 
W. Ronald MofFitt. M.D.. Hendersonville. NC 
Mark D. Monson. M.D.. Spartanburg. SC 
Donna L. Prather. M.D.. Carrboro, NC 
John V Pruitt 111. M.D.. Boston. MA 
Peter A. Schlesinger. M.D,. St. Paul. MN 
Stuart C, Segerman. M.D.. .Atlanta. GA 



Susan T. Snider, M.D., Burnsville, NC 
William D. Snider, .M.D., Chapel Hill, NC 

Donna S. Sperber. M.D.. St. Petersburg. FL 
Alan D. Stiles. M.D.. Chapel Hill. NC 
Gregory H. Tuttle. M.D.. Mebane. NC 
Wilham A. Walker. .M.D.. Charlotte. NC 
J. Byron Walthall. Jr.. M.D. and Nancy L. 
Teafl. .M.D.. Charlotte. NC 
Richard C. Worf. M.D.. Winston-Salem. NC 

CLASS OF 1979 

Number in Class: 128 

Percent Donors: 28.1% 

Andrew H, Balder. .M.D.. Longmeadow. MA 

Gail .M. Capel. .M.D.. Schenectady. NY 

D. Franklin Craig. M.D.. Burnsville. NC 

Waller E. Daniel. Jr.. M.D.. Raleigh. NC 

Douglas M. Delong. M.D.. Ladysmith. WT 

Allen R. Edwards. M.D. and Palncia K. Hill. 

M.D.. Statesville. NC 

Ellen B. Fitzgerald. M.D.. Lexington. KY 

Sharon M, Foster. M.D.. Raleigh. NC 

Thomas R. Hinson. Jr.. M.D.. Clemmons. NC 

Kent M. Kalina. M.D.. Charlotte. NC 

Anne T. Keifer. M.D. and John C. Keifer. M.D.. 

Chapel Hill, NC 

John M. Lafferty. M.D.. Valdese. NC 

Charles E. Lownes. M.D.. Greensboro. NC 

Julia E, McMuiTay. M.D,. Madison. Wl 

Darlyne Menscer, .M.D., Charlotte. NC 

Harold P Overcash. MD.. Raleigh. NC 

Christian E. Paletta. M.D., St. Louis. MO 

Lawrence H. Pearson. M.D., Shelby. NC 

James G. Peden, Jr.. M.D.. Greenville. NC 

Alan M. Ranch. M.D.. Santa Barbara. CA 

Charles N. Reed. M.D.. Hickory. NC 

J, Mark Rowles. M.D.. .Atlanta. GA 

James L. Sanderford. Jr., M.D., Lewisville, NC 

David M. Siegei. M.D.. Rochester. NY 

William L. Stewart. M.D.. Southern Pines. NC 

Frances R. Thomas. M.D.. Chicago. IL 

Paul A. Vadnais. MD.. Charlotte. NC 

Lynn E. Wesson. M.D,. Raleigh. NC 

Mack W. White III. M.D., Charlotte, NC 

C, Phillip Whitworth. M.D.. Forest City. NC 

Lan-y T Williams. M.D,. Hickory. NC 

Leonard S. Wojnowich. M.D.. Savannah. GA 

O. Ban-y Wynn. M.D. and Michelle H Wvnn. 

M.D.. Charlotte. NC 

CLASS OF 1980 
Number in Class: 145 
Percent Donors: 36'7<- 

Edward H. Bertram 111. M.D,. Charlottesville. VA 
Roger D, Billica. M.D.. Houston. TX 
Marcus E. Carr. Jr.. M.D.. Midlothian. VA 
Wilbur B. Carter. Jr.. M.D.. Chapel Hill, NC 
Lauren E. Cosgrove. M.D., Potomac. MD 
Phillip K. Dorton. M.D.. Thomasville. NC 
Patricia T. Edkins. M.D.. Chapel Hill. NC 
W. Wells Edmundson. M.D.. Raleigh. NC 
Walter E. Egerton 111. M.D.. Aberdeen Proving 
Grounds. MD 

C. O'Neil Ellis, M.D.. Matthews, NC 
Barry J. Freeman. M.D.. Los Angeles, CA 
Fredenck U. Goss. M.D.. Salisbury. NC 
John C. Gudger. M.D.. Swansboro. NC 
Sandra K. Haigler. M.D.. Lexington. KY 
Catherine J, Hants. M.D.. Wilmington. DE 
Call L, Havnes. Jr. M.D,. Kinston. NC 



Mark A. Helvie. M.D,. Ann Arbor. MI 

J. Patrick Holland. .M.D., Winston-Salem, NC 

Kenneth E. Hollingsworth. M.D.. OIney. MD 
Philip R. Johnson, Jr.. M.D.. New Albany. OH 
Edward C. Jones. M.D.. Clemmons, NC 
Konrad C. Kaltenbom. M.D.. Anchorage. AK 
Daniel M. Lewis. M.D.. Charlotte. NC 
Thomas H. Lineberger. M.D.. Pinehurst. NC 
Jimmy Locklear. M.D.. Raleigh. NC 
William L, Lowe. Jr.. .M.D.. Winnetka. IL 
Christine C, Mahvi. .M.D.. Middleton. Wl 
E. John Markasheuski. Jr.. M.D.. Huntsville. AL 
Steven K. .McCombs. M.D.. Chapel Hill. NC 
T. Michael O'Shea. Jr. ,M.D.. Wniston-Salem. NC 
Cort A. Pedersen. M.D.. Chapel Hill. NC 
Dwight D, Perry. M.D, and Veronica J. Ray. 
M.D.. Durham. NC 

R. Brookes Peters IV. M.D.. Tarboro. NC 
Bayard L. Powell. M.D.. Winston-Salem. NC 
Timothy A. Presnell. M.D.. Richlands. VA 
Pctnc M, Rainey. MD.. Lake Forest Park. WA 
Judith L. Rissman. .M.D.. Lexington. MA 
Steve E. Ritchie. M.D.. Knoxville.TN 
Suzanne Rogacz. M.D.. Potomac. MD 
J. McNeill Smith 111. M.D.. Asheville. NC 
Paul C. Sorum. M.D.. Schenectady. NY 
James P. Srebro. M.D.. Napa. CA 
Walter J. Steele. M.D.. Charlotte. NC 
Karin R. Sternberg. M.D.. Pittsford. N\' 
Leslie L. Taylor 111. M.D.. Smithfield. NC 
James V Taylor III. M.D.. Wilson, NC 
Donna W. Tilson. M.D.. Louisville. KY 
Jonathan P. Tolins. M.D.. Minneapolis. MN 
Margo F, Tolins-Mejia. M.D.. Minneapolis. MN 
Liliana Ci. Visscher. M.D.. Cape Girardeau. MO 
Kenneth W. W ilkins, Jr., M,D., New Bern. NC 

CLASS OF 19S1 

Number in Class: 159 

Percent Donors: 32.7% 

(;. Williams .4dams. M.D. and Deborah L. 

Fussing. .M.D.. Scverna Park. MD 

Lee P Adlci. M.D.. Winsion-Salem. NC 

Paul S. Andrews. M.D.. Chapel Hill. NC 

David Shields Barnes. M.D. and Elizabeth Scott 

Babcox. M.D.. Shaker Heights. OH 

Craig R. Bennett. M.D.. North Wilkesboro. NC 

Philhp M, Bridgman. MD.. Hannawa Falls. NY 

Stephen E. Buie. .M.D,. Asheville. NC 

(iraham W. Bullard. M.D.. Cornelius. NC 

Lena W, Butterworth. .MD,. Charlotte. NC 

David .4. Crews. M.D. and Elizabeth A. Eagle, 

.M.D.. (Jreensboro. NC 

Deborah H. Davis. M.D,. Morganton. NC 

David M. Deitz. M.D.. Olympia. WA 

Amelia F Drake. MD.. Chapel Hill. NC 

Frederick M. Dula. Jr.. M.D.. Salisbury, NC 

David A. Goff. M.D.. Raleigh. NC 

David K. Harper, M.D.. Concord. NC 

William M. Herndon. Jr.. M.D.. Charlotte. NC 

G. Wallace Kernodle. Jr.. M.D.. Burlington. NC 

Douglas P Kiel. M.D,. Medfield. MA 

Garland C, King. MD,. Franklin. NC 

Alan S. Kopin, M.D., Wellesley Hills. MA 

R. Wayne Kreeger. M.D.. Atlantic Beach. FL 

Leigh S. Lehan. M.D.. Raleigh. NC 

Robert E. Littleton. M.D.. Raleigh. NC 

Nanetta B, Loue-Roache. M.D.. Winston-Salem. NC 

Jane E. Lysko, M.D., Asheville. NC 

Saundra A. Maass-Robinson. M.D.. East Point. GA 



John R. Mangum. M.D.. Sanford. NC 

W illiani H. Menvm. Jr.. M.D. and Man -Frances 

Meruin. Knowille. TN 

Catherine H. Messick, M.D.. \\ iaston-Salem, NC 

Charles B. Nemerot=l'. M.D.. Ph.D.. .AUanta. G.-\ 

J Thomas Newton. M.D.. Clinton. NC 

Larry C. Nickens. M.D.. Goldsboro. NC 

William B. Olds. M.D.. Rovboro. NC 

Paul M. Parker. M.D. and Ruth M. Parker. 

.\I.D.. .Atlanta. G.\ 

Peter L. Pleasants. M.D.. Providence. RI 

Larn, B. Poe. M.D.. Binghamlon. NY 

Teresa A. Rummans. M.D.. Rochester. MN 

Timothy G. Saunders. M.D.. Charlotte. NC 

Thomas J. SeeK. .\I.D . Summerfield. NC 

Ehvood E. Stone. Jr.. M.D., Cedar Rapids. \.\ 

William W. Stuck. .M.D.. Columbia. SC 

James D. V\hinna. M.D . Monroe. NC 

.Susan M. Whitehead. Mancos. CO 

Carol J. Wilkerson. M.D.. .Alexandria. V.-\ 

Phillip M. Williford. M.D.. Winston-Salem. NC 

Warden L. Wbodard III. M.D.. Charlotte. NC 

Michelle H. Wynn. M.D. and Ossian B. Wynn. 

M.D.. Charlotte. NC 

CL.XSSOF 19S: 
Number in Class: 153 
Percent Donors: ILf^t 

John C .Adams. M.D.. Indian Trail. NC 
Joseph L. Albright. Jr.. M.D.. Chariotte. NC 
.Mary John Ba\le\. M.D . Greensboro. NC 
Barbara L. Bethea. .M.D.. Lillinglon. NC 
Peter H. Bradshaw. M.D.. Hickory. NC 
J. Lawrence Brady. Jr.. M.D.. Charlotte. NC 
David W. Cash. M.D.. Statesville. NC 
N.incy C. Chescheir. NLD.. Chapel Hill. NC 
Bruce V. Darden II. M.D.. Charlotte. NC 
Robert C. Dellinger. Jr.. M.D.. High Point. NC 
Cindy S. Dieringer. M.D.. Camden. SC 
Lawrence M. Fleishman. M.D,. Charlotte. NC 
Charles J. Fulp, Jr.. M.D.. Atlanta. GA 
John S. Gaul III. M.D.. Charlotte. NC 
Thomas W. Graham. M.D.. Carrboro. NC 
Stephen .M. Hux. M.D.. Winston-Salem. NC 
Timothy O. Jenkins. .\I.D.. Concord. NC 
Beverly N. Jones III, M.D.. Winston-Salem. NC 
Kathi J. Kemper, .M.D.. Boston. MA 
Angela Kendnck. .M.D.. Aloha. OR 
Virginia E. Killough. M.D.. Marquette. Ml 
Marian S. Kirkman. M.D.. Carmel. IN 
Vincenl J, Kopp. M.D . Chapel Hill. NC 
.Mary I. Korytkouski. .\I.D., Pittsburgh. P.A 
Jackie A. Lucas. M.D.. Charlotte, NC 
James T. Massagee, M.D.. Greensboro, ,NC 
Linville M. Meadows. M.D.. Jacksonville. FL 
Horace W. .Miller IV, M.D.. Fayelteville, NC 
Myrlin L. Murphy, M.D.. Chapel Hill. NC 
Mark D. Peacock. M.D.. Mooresville. NC 
Donald W Peters. M.D . VSinstonSalem. NC 
Rildia J. Pritchelt. M.D.. Gary. NC 
Eric D. \an Tassel, M.D.. Asheville. NC 
Kathryn I,. VVeise. M.D.. Cleveland Heights. OH 
Stanley A. Wilkins, Jr. M D . Raleigh. N( 

(I \SSOF IW.^ 

Number in Class: 157 

Percent Donors: 2l.T7r 

David J Ballard. Ml).. Ph.D.. Dallas. TX 

Thomas W. Benton. M.D.. Charlotte. .NC 

Marsha F Benholl, .M.D . Jacksonville. FI. 



James A. Bryan 111. M.D.. Chapel Hill. NC 
\incenl K. Cheek. M.D.. Greensboro, NC 
Douglas W, Clark. M.D . Chapel Hill. NC 
R. Caner Clements. M.D.. Oakland. CA 
Ronald W. Cottle. .M.D.. Florence. SC 
.Mark H. Davis, M.D.. Crescent City, CA 
Mary Anne Dooley, M.D.. Chapel Hill. NC 
Nancy L. Earl. M.D., Chapel Hill, NC 
James L. E\erette. Jr.. M.D.. Dover. DE 
.\Iich.iel B, Fischer. M.D,. Glastonbury. CT 
kimberly S, Haltiw anger. MD,. Scl.iuket. NY 
John .M. Herion. M.D.. Wilmington. NC 
Thomas T. Hunter. M.D.. Jacksonville. NC 
Barbara E. Johnston. M.D.. New York. NY 
Elizabeth Kopin. M.D..Wellesle> Hills. MA 
James D L.idd. MD.. Ashe\illc. NC 
Peter J, Larson. M.D,. Oakland. CA 
Franklin Webster Maddux. MD, and Dugan 
Wiess .Maddux. .M.D.. Danville. VA 
Ovela B. Mcintosh- Vick. M.D.. Durham. NC 
Margaret N. Morris. M.D.. Asheville. NC 
James C, Osborne. M.D.. Greensboro. NC 
Catherine C. Pamsh. MD.. Ellicott City. MD 
Gail L, Shau, M.D., Odessa. FL 
Hermon W. Smith 111. M.D.. West Friendship. MD 
Eugene R. Soares. M.D,. Dover. NH 

C. Stephen Stinson. M.D., Winston-Salem. NC 
Gregory .A. Underwood. M.D.. Charlotte. NC 
Mary C. Wasko. M.D.. Pittsburgh. PA 

John H, Williams. M.D.. Raleigh, NC 
Lawrence M. Wyner. M.D.. Charleston. WV 
Princess W. Yousem, M,D,. Pittsburgh. PA 

CLASS OF 14S4 
Number in Class: 144 
Percent Donors: 29.9 '7<^ 

James P Alexander. Jr.. MD,. Decatur. GA 

D. Antonio Bell. M.D. and Amelia K Bell. .M.D.. 
Cornelius. NC 

Steven J. Citron. M.D.. Dunwoody. GA 

Patncia F Culhane. M.D., Campbell. CA 

.Alain T. Drooz, M.D.. Vienna. V.A 

Eli D. Finkelstein. M.D.. Edison. NJ 

Kathleen J. Foster-Wendel. MD,. Ames. lA 

Siephen h, Gitelman. M D,. San Francisco. CA 

Ronald \>. Hargrave. M.D.. Mt. Pleasant. SC 

James R. Harper. Jr.. .M.D.. W ilmington. NC 

James C, Hill. M.D.. Cary. NC 

Janice R. Hossler. M.D.. Columbia, SC 

Linda E, Jafte. M.D.. Wilton. CT 

Paul A, James. .M.D,. Williamsville. N'l' 

.Michael J. Knight. M.D.. North Hampton. NH 

Marcia A. Koomen. M.D., Chapel Hill, NC 

Elizabeth W. Koonce, M.D.. Charlotte. NC 

Robert P. Lineberger. M.D and Catherine K 

Lineherger. M.D.. Chapel Hill. NC 

Jo .M, Mailiirano. MD,. lexinglon, SC 

Jane H. Murray. M.D.. Durham. Nl 

Howard W. Newell. Jr.. .M.D.. Goldsboro. NC 

R. Claiborne Noble. M.D.. Raleigh. NC 

Douglas W. Peed. M.D.. Chapel Hill, NC 

Ronald E. Pruitt. M,D„ Nashville. TN 

Allred L. Rhyne 111. ,M.D . Charlotte. NC 

Richard (;. Saleehy. Jr.. M.D. and Jackie A. 

Niwlin-Saleeln. M.D.. Raleigh. N( 

Kolvn ,\ S.iiiiiii(.ns. Ji . MD, (ii.iikl Junciion.CO 

David I.. .Sappenfield. M.D.. Durham. N( 

Paul W Sassei. MI). Lden. NC 

.Mary A Saunders, NLD., Springfield. IL 

John .\1 Schollstall. M.D.. Glen Mills. PA 



Thomas E. Shook. M.D.. Savannah. (J.A 
Thomas C. Spangler. M.D.. Winst<m-Salem. NC 
Sharon R. Stephenson. M.D.. Cary. NC 

Nathan R. Strahl. \1 I) . Ch.ipel Hill, NC 
Paul E. Viser. M.D.. t linton. NC 
Robert A. Wainer. M.D.. (ireensboro. NC 
Rolf B. WaUin. M.D.. Fayelteville. NC 

Robert E. Wiggins. Jr.. M.D,. Ashe\ille, NC 
Daniel W. Wilhams 111. M D.. Lewisville. NC 

CLASS OF iyS5 
Number in Class: 159 
Percent Donors: ^.^..^'^i- 
A, Elizabeth Allen. M.D . Winsum-Salem. NC 
Sebastian R, Alsion. M D,. Jackson. GA 
S. Leonard Auman. Jr.. M.D.. Dallas, TX 
Leslie A. Bunce. MD,. Ch.ipel Hill. NC 
Charles L, Carter. M.D.. Memphis. TN 
Kathleen M. Clarke-Pearson. M.D.. Chapel Hill. NC 
Jonathan S. Cohen. M.D.. Signal Mountain. TN 
Susan L. Cookson, M.D.. Stone Mountain. GA 
Laura L. Crow. MD.. Greensboro. NC 
Cynthia H, Dent. M.D.. Cro/et. VA 
Douglas S. Diekema. M.D,. Kenmore. W.A 
Cymhia B Dunham. M.D.. Chapel Hill. NC 
Douglas Shure Feltman, NLD. and Gwenii 
Elizabeth McLaughlin. M.D., Miami, FL 
Kenneth E. Ferrell. Jr.. M.D.. Charlotte, NC 
Margaret K, Fikrig. M.D.. Guilloid. CT 
Catherine G. Fuller. M.D.. Los Angeles. CA 
John H. Gilmore, Jr.. MD.. Chapel Hill. NC 
Pamela P. Golden. M.D.. Tucson. .AZ 
Charles S. Hayek. M.D.. Shelby. NC 
Brentley D. Jeffries. M.D.. Ashev ille. Nt 
Margaret G. Johnson, M.D.. C hapel Hill. N( 
Stuart HaiTington Jordan. MD, and Sher\l Ann 
Gillikin. M.D.. Fayetteville. NC 
Dr. Peter M. and Mrs. Rebecca A, Jordan. 
Greensboro. NC 

David C. Joslin. MD,. Greensboro. NC 
Theodore C. Kerner, Jr.. M.D., Lewisville. NC 
John A, Kirkkind. Jr. M.D.. Charlotte. NC 
Mark H. Knelson. M.D.. Durham. NC 
Joyce K. Lammert. MD . .Senile. \\A 
James W, Ledeiei. Jr. MD . Ad^.ince. NC 
Elizabeth S. McCuin, M.D.. Roanoke. \A 
Nancy H .Miller. .M.D.. Longmeadow. MA 
Stephen B. Mitchell. M.D.. Moiehead. KY 
Terrence D. Morton. Jr. M.D.. Moorcsville. NC 
Albert R Munn 111. M D .ind Iis.i F Deiaincllc. 
M I) . Raleigh. NC 

Robert F. .Murray III, .M.D.. Pleasant Ridge. Ml 
Albert J. Osbahr III, M.D., WaynesMlle. NC 
Leslie K. Paulus. M.D.. Phoenix. A/ 
Fredertck B, Payne. Jr. MI). Fayelle\ illc. NC 
Joel K. .Schneider. M.D.. Raleigh, N( 
Martin E, Slieline. .MD . Allanla. <,A 
McCriieS. Smith. Ml) and Haibai.i II Sniilh. 
M.D.. Greensboro. NC 
G King Snyder. Jr.. M.D.. Rye. CO 
S. Patrick Stuart. Jr.. M.D.. Winston-Salem. NC 
Dorothy E. Thomas, M.D.. LouismMc. K'i 
Claudia L. Thomas. M.D.. Sands Point. N^l' 
Bradley K Wcisiier. .MD,. Ch.irloite. NC 
Randall W Williams. MI),. Raleigh. NC 
Robert S /.uckei. Ml). lampa. FL 
Sheine i;, /weig. MD,. Chapel Hill. NC 

(1 \SS (1| I'ISf) 
NinnlH-r in (lass: 155 

35 



I'erctnt Donors: 16.8'7f 

Sic\en J. Baumrucker. MD.. Church Hill. TN 
J Lancaster Bridgeman. Jr.. M.D.. Greenville, SC 
M. Todd Brown. M.D.. Charlotte. NC 
Charles B. Cairns. M.D.. Denver. CO 
Michael D. Carter, M.D. and Mary Beth A. 
Carter. M.I)., Wilmington, NC 
James W Cheek. M.D., Jacksom lUe. FL 
William M. Clark. Jr. M.D. and Elizabeth T. 
Clark. M.D.. Oak Park. IL 
Herbert (J. (iarrison HI, M.I) and Lynne C. 
(iarrison, M.I)., (Jreenville, \C 
hh/abeth V. Getter. .M.D.. New 'lork. N"! 
Pamela G. Hanna, .MD., Cornelius. NC 
Connie D. Hamll. M.D.. Indianapolis. IN 
,). Curtis Jacobs, .M.D., High Point. NC 
Jonathan K. Le\ine. M.D., Charlotte, NC 
Leslie C. McKinney. M.D.. Raleigh. NC 
Michael E. Nonns. M.D.. M.PH.. Greensboro. NC 
.Steven R. Olson. M.D.. Greensboro, NC 
C. W. .Sotley. Jr., M.D.. Anderson, .SC 
Cathy Jo W. Swanson, M.D., Roanoke, V.A 
Beverly J. Waddell, M.D., Lorton, VA 
L. Tyler Wadsworth III, .M.D. and Deborah T. 
Wadsworth, .M.D., Des Peres, MO 
CaKin G. Warren, Jr, M.D.. New Bern. NC 
James C. Womble. M.D.. Car>. NC 

CLASS OF 14,S7 
Number in Class: 156 
Percent Donors: 30.1% 

Steven H. Baker. M.D.. Asheville, NC 

Thomas H. Belhom. M.D.. Ph.D. and Linda R. 

Belhorn. M.D., Chapel Hill. NC 

William S. Blau. M.D.. Ph.D.. Chapel Hill. NC 

David W. Boone. M.D.. Raleigh. NC 

Mehssa W. Bureh. M.D.. Orono. ME 

Lisa A. Chnstman. M.D.. Raleigh. NC 

(;regor (J. Cleveland, .M.I).. Ph.D.. 

TInimonsville, SC 

James B. Collawn. M.D.. Raleigh, NC 

Carey G. Cottle. Jr.. M.D.. Greensboro. NC 

James Earl Crowe. Jr. M.D. and Elizabeth H. 

C"rowe. M.D.. Brentwood. TN 

Lochrane G. Davids, .M.D., (Jreenville, SC 

I. Gordon Early. Jr. M.D.. Spartanburg. SC 

Lee A. Furlong. M.D.. Seal Rock. OR 

Jani.i B. Greene. M.D.. Rock\ Mount. NC 

W Slu.irt Hartlc>. M.D.. Charlotte. NC 

Richard H. Havunjian, M.D., Los .Angeles, C.\ 

James P. Hoolen. Jr.. M.D.. Elon College. NC 

Dennis N. Jacokes. M.D. and Allison L. Jacokes. 

M.D.. Raleigh. NC 

William W, King. M.D.. Wilmington. NC 

Thomas E. Lawrence. M.D.. Greensboro. NC 

Susan R. Leiw. M.D.. Roanoke. \'.\ 

Ciusta\ C. .Magrinat. NLD.. Greensboro. NC 

Teresa B. .Vlelvin. M.D.. Moores\ille. NC 

Sherry L. Morris, M.D., Harrisonburg, \A 

Peter R. Muller. NLD.. Charlotte. NC 

Lisle M. Nabell. M.D.. Bimiingham. AL 

Thomas E. Paulson. M.D.. Sacramento. CA 

Nancy \\. Phifer. M.D., Burlington, NC 

Mark K. Robbins, M.D., Charlottesville. VA 

David B. Robinson. M.D.. M.RH.. Auke Ba\, AK 

C. Alan Ross, M.D., Summerfield. NC 

Daniel M. Sappenfield. M.D.. Charlotte. NC 

Constance J. Sewell. M.D.. Asheville. NC 

Ronald B Shapiro. M.D.. Austin. T.\ 

Da\id L. Sheppard. M.D.. Gull Breeze. FL 

36 



Robyn L. Stacy-Humphries, M.D., Charlotte, NC 

Brian S. Strauss. .M.D.. High Point. NC 
William R. Sutton. M.D.. Wilmington. NC 
Victoria B. Teague. M.D.. Alpharetta. G.\ 
Obinnaya C. Umesi. M.D.. Durham. NC 
Roben M. Walasin. M.D.. Chapel Hill. NC 
Da\id C. Ward. M.D.. Chapel Hill. NC 
Jonathan J. Weiner. M.D.. Durham. .NC 
Paul A. 'loung. M.D.. APO. AE 

CLASS OF 19SS 
Number in Class: 154 
Percent Donors: 27.9% 

C. Trent Blackman. M.D.. Concord. NC 
Jon P. Brisley. .M.D.. Roanoke. \ A 

Brenton T. Burkholder. M.D.. Atlanta. GA 

J. Craig Charles. M.D.. Winslon-Salem. NC 

Jack .M. Cole, M.D., Moore, SC 

Debra L. Coles. M.D.. Charlotte. NC 

Jonathan B. Covey. M.D.. Pueblo, CO 

Peter G. DalldorL M.D.. Greensboro, NC 

Keith A. Davis, M.D., San Diego, CA 

Paul R. Eason, M.D. and Margie B. Eason, M.D., 

Martinsville, V.A 

C, Gaelyn Garrett, M.D., Nashville. TN 

Kirslen G. Girkins. M.D.. Charlotte. NC 

Frenesa K. Hall. .VLD.. Lilbum. GA 

Elizabeth H. Hamilton. M.D.. Chapel Hill. NC 

Da\id W. Herion. M.D.. Bethesda. MD 

Hunter A. Hoover. M.D.. Charlotte. NC 

C. David Johnson. M.D.. BIythewood. SC 

Kathryn P. King, M.I)., Carrboro, NC 

Hannah R. Krigman, M.D., St. Louis, MO 

Ritsu Kuno. M.D.. .Midlothian. VA 

Jane M. Laco. .M.D.. Plymouth. MN 

Stuart J. Levin. M.D.. Raleigh. NC 

Thaddeus L. McDonald III. M.D.. Raleigh. NC 

Marsden H. McGuire. M.D.. Baltimore. MD 

Philip J. Nahser. Jr. .M.D.. Greensboro. NC 

Charles E. Parke, M.D., Greenville. SC 

Richard M. Peek. Jr. M.D. and Julie T Peek. 

M.D.. Nashville. TN 

Gary L. Pellom. M.D.. Durham. NC 

John E. Perry III. M.D.. Raleigh. NC 

H. Kyle Rhodes. M.D.. Wilmington. NC 

Jeffrey E. Roller. M.D.. Morganton. NC 

George H. S. Sanders. M.D.. Jamestown. NC 

Charles D. Schcil. M.D.. Hickory. NC 

J. Robert Siher. M.D.. Charlotte. NC 

Mary E Smith. M.D. and Bryan W. Smith. M.D.. 

Chapel Hill. NC 

Daniel J. Stackhouse, M.D., Charlotte, NC 

John D. S\ nianski. M.D.. Charlotte. NC 

Roger P Tart. M.D.. Mobile. AL 

Edward W. Whitesides, M.D., Wilmington, NC 

Elliott E Williams. M.D.. High Point. NC 

CLASS OF 1 y.s^ 
Number in Class: 146 
Percent Donors: 24.0% 

Paul E. Austin. M.D.. Durham. NC 

Scott M. Baker, M.D. and Kristin D. Baker, 

M.D.. Concord, NC 

Robert S. Bein, M.D., Green\ille. TN 
L. Katheiine Bliss, M.D., Etland, NC 
Lisa K. Burke, M.D.. Marietta. GA 
.Margaret F. Campbell. M.D., Greensboro, NC 
Peter N. Copsis. M.D., Matthews, NC 
Brcnda K. Cowell. M.D.. Charlotte. NC 
Daniel T Goulson. M.D.. Levinsiton. K^' 



Douglas B. Hansen. M.D.. Rock Hill. SC 
Mary E Hebert. M.D.. Denison. T\ 
Rosemary Jackson. M.D.. Bahama. NC 
Daniel M. Kaplan, M.D., Raleigh, NC 
Michael W. Keeley. .M.D.. Shelby. NC 
William H. Kelly. M.D.. Fayetteville. NC 
Charles G. Lampley IV. NLD.. Shelby. NC 
William L. Lawing. M.D.. Winston-Salem. NC 
Johnnie A. Lee. M.D.. Fuquay Varina. NC 
Kenneth S. Maxwell. M.D.. Winston-Salem. NC 
James M. McLean. M.D.. Winston-Salem. NC 
Melissa M. McLeod. M.D.. Norfolk. VA 
Jay B. .Michael. M.D.. Fayetteville. NC 
H .Merle Miller. M.D.. Boulder. CO 
Linda K. .Mitchell-Fry e. M.D.. Laurel. NC 
Robert F Noel. Jr.. .VLD.. Henderson. NC 
Lisa C. Richardson. M.D.. Clarkston. GA 
Mary D. Shearin. M.D.. Jamestown. NC 
Arthur J. Shepard III. M.D. and 
Nicole P Shepard. M.D.. Albany. GA 
Ci. Bradley Sherrill. M.D.. Greensboro. NC 
Patricia G. Singer. M.D. and J. Daniel Singer. 
M.D.. Greensboro. NC 
John H. Stephenson. M.D.. Roswell. GA 
Jon R Woods. M.D.. Madison. Wl 

CLASS OF \W{) 
Number in Class: 153 
Percent Donors: 30.7% 

Lori W. Balahan, M.D.. Charlottesville. VA 
John E. Barkley. M.D., Charlotte. NC 
Ronnie J. Bamer. M.D.. Salisbury. NC 
Elizabeth D. Bell. M.D.. Chapel Hill. NC 
Robert M. Bernstein. M.D.. Seattle. WA 
Anna P Bettendorf. M.D.. Durham. NC 
Cednc M. Bnghl. M.D.. Durham. NC 
Betsy E. Brown. M.D.. Seattle. WA 
Martyn J. Cavallo. M.D.. Nash\ ille. TN 
Sandra C. Clark. M.D.. Chapel Hill. NC 
Scott M. Cochrane. M.D.. Amherst. MA 
Catherine L. Cooper. M.D.. Richmond. V.A 
Todd S. Cowdery. M.D.. Eastsound. WA 
C. James Cummings. M.D.. .Asheville. NC 
Terri W. Cummings. M.D.. Stone Mountain. GA 
William De Araujo. .M.D.. Goldsboro. NC 
Ban-y T Degregono. M.D.. Portland. OR 
Jon P Donnelly. M.D.. Cape Elizabeth. ME 
Thomas E Edwards. Jr. M.D.. Atlanta. GA 
Robert R. Ehinger. .M.D.. Greensboro. NC 
John W. Entwislle III. M.D.. Lafayette Hill. PA 
Mary I. Fatehi. M.D.. Englewood. NJ 
.Mark T. Hooten. M.D.. Rock Hill. SC 
R. Lynne Homsby. M.D.. Greenville. SC 
Stacey N. Ibrahim. M.D.. Asheville. NC 
Dominic .A. Jaeger. M.D.. Burlington. VT 
Leigh H. Jones. M.D.. Greensboro. NC 
John H. Kiege. M.D.. Greensboro. NC 
Philip C. Lackey. M.D. and Victona D. Lackey. 
M.D.. Charlotte. NC 
Edward I. Lee. M.D.. Winchester. VA 
Lon B. Lilley. M.D.. Raleigh. NC 
Linda J. Matthews. M.D.. Huntersv ille. NC 
Nicolette B. Naso. M.D. and William B. Naso. 
.M.D.. Florence. SC 

Todd G. Owsley. DDS. M.D.. Greensboro. NC 
Whitman L. Reardon. M.D.. Chapel Hill. NC 
J. Gardiner Roddey. Jr. M.D. and Patricia K. 
Rodde\. M.D.. Charlotte. NC 
Ami J. Shah. M.D.. South Pa.sadena. CA 
Eugenia B. Smith. M.D.. Chapel Hill. NC 



Murphy F Townvend III. M.D.. Atlanta. G.A 
Craig W ierum, M.D.. Nashville, TN 

J. Todd Williams. M.D.. .Asheboro. NC 
.Adam S. Wilson. M.D.. \ancou\er. \\.-\ 
John H. Wood. M.D.. Chapel Hill. NC 
Mark W. Zimmerman. M.D and 
Sherri .A. Zimmemian, M.D.. Car>. NC 

CL.-XSSOF 1441 

Number in Class: 157 

Percent Donors: 24.8'> 

Katrina H. .Avery, M.D.. Durham, NC 

Mack N Barnes III. M.D.. Bimiingham, .\L 

Roben P Bnaht. M.D., Durham. NC 

Roben C Brooks. M D . Pittsburgh. P.A 

N. Elaine Broskie. M.D.. Salem. OR 

M. Elizabeth Brown. .\I D.. Summert'ield. NC 

Linda H Butler. M D . Raleigh. NC 

Thomas R. Coleman. M.D.. Lut/. PL 

Roben L. Cook. M.D.. Pittsburg. P.A 

William W. Crone. M.D.. .Atlanta. G.A 

Amy C. Degnim. M.D.. Leeds. M.A 

Cathenne M. Gordon. M.D.. Wellesley. M.A 

Bnan H. Hamilton. M.D.. Charlotte. NC 

Leon W, Hemdon. Jr. M.D. and 

^olanda \'. Scarlett. M.D.. Hillsborough. NC 

W Barlou Inabnet III. M.D.. Neu fork. NY 

l)re« A. Jones. M.D.. Greensboro. NC 

Seth E. Kat/. M.D.. San Diego. C.A 

W P Killam. M.D.. Fort Defiance. .AZ 

.Michael J. Lucas. M D.. High Point. NC 

Constantine G. Marousis. .M D . West Palm 

Beach. FL 

James J. McCarthy. M.D.. Menon Station. PA 

Todd D. McDiannid. M.D.. Greensboro. NC 

Scott R. McDuffie. M.D.. Sumter. SC 

Jobe C. Metts 111. M.D.. Mount Pleasam. SC 

Linda M, Nicholas. .M.D.. Chapel Hill. NC 

Vincent C. Phillips. M.D.. Engleuood. OH 

Richard J, Pollard. M.D. and 

Helene R Keyzer-Pollard. M.D . Gastonia. NC 

Danny Silver. M.D.. Raleigh. NC 

Bnan D. Smith. .M.D.. Shelby. NC 

Todd F Tanner. .M.D.. Goldsboro. NC 

Paul C. Tobin. M.D. and Rebecca B Tobin, Ml). 

Chapel Hill. NC 

Gilbert R. Upchurch. Jr. M D . Ann .Arbor. .Ml 

Andrew B. Wallach. .M.D.. New York. NY 

Frederick M. Weeks. M.D. and Margaret W. 

Weeks. M.D.. Vero Beach. FL 

Patrick .A. Wilson. M.D.. Wihnington. DE 

Edward H. Wrcnn. M D.. Pittsburgh. PA 

CLASS oi- iw: 

Number in Class: 157 

I'lrcint Donors: 2(1. -I'r 

Jorge A Allende. Jr. M.D . Fort Collins. CO 

Mary M, Bledsoe Felkner. M.D.. Charlotte. NC 

Lisa A. Brone. .M.D.. .Abescon. .NJ 

Nancy C. Clayton. M.D.. Chapel Hill, NC 

Gerald E. Cooley. M.D. and Amy R. Cooley. 

MD. Charlotte. NC 

Christopher C. Cosgrose. M D. and 

Billie F Cosgrove. M D . Wilmington. NC 

Cynthia K. Crews. M.D . Den\er, CO 

Mary J. Forbes. M.D.. Raleigh. NC 

Scolt K. Garrison. M.D.. Raleigh. NC 

James G. Hall. .M.D.. Durham. NC 

Mark W. Jenison. M.D.. Virginia Beach. VA 

Pamela C. Jenkins. .M.D.. Lvmc. NH 



Andy C. Kiser. M.D., Whispering Pines. NC 

Ban-etl T. Kitch. M.D.. Cambridge. MA 

David A. Konanc. M.D.. Raleigh. NC 

Susan R. Marcinkus. .M.D.. Luther\ille. MD 

Walter S. Moms III. M.D.. Southern Pines. NC 

Martin T. Noveinber. M,D.. Cambridge, M.A 

Edward J. Pnmka 111. M.D, and Lynda R. Pnmka. 

M D. .A\onLake. OH 

Anand \'. Ramanathan. M.D.. Darien. IL 

Hans P Roethlmg. M.D.. C.oldsbor,.. NC 

J Cullen Riitl. M.D.. Arlington. \A 

Scott \'. Smith. .M.D.. Ape\. NC 

Anjali M. Sues. M.D.. Raleigh. NC 

Thor O. Svendsen. M.D.. Chariottc, NC 

Rita E. Treanor-Plemmons. M D.. Envin. TN 

Charles D. Wells. M.D.. Atlanta. GA 

Bradford Tracy WinsKm. M.D, and Lisa Corbin 

Winslou. MD.. Denver. CO 

CLASS OF IW,^ 
Number in Class: 145 
Percent Donors: 21.4'<- 

Aleta A, Borrud. M.D,. Rochester. MN 
Rochelle M, Brandon. M.D.. Charlotte. NC 
Tamara W, Bnngewatt. MD,. Davidson, NC 
Harry L. Broome. Jr.. M.D.. Phoeniv. AZ 
John S. Chase. M.D., Iowa City. lA 
John D. Corey. M.D.. Carrboro. NC 
William L. Craig III. M.D.. Raleigh. NC 
Carolyn J. Dalldorf. M.D.. Chariottesville. VA 
Karia L. Debeck. .M.D.. Durham. NC 
Cathy .A. Donovan. .M.D.. Onainia. MN 
S, Lynn Gardner. M.D.. Stone Mountain. G.A 
J. Judd Green. Jr. M.D.. Jamestown. NC 
Thomas M. Haizlip. Jr. M.D.. Banner Elk. NC 
Joseph 1, Harwell. .M.D.. Sharon. MA 
C. Anthony Kim. M.D.. Puyallup. WA 
Eugene H, Maynard. Jr. M.D.. Smithfield, NC 
Jennifer L. Miles, M.D.. Oakland. CA 
John D. Phipps. M.D.. Winston-Saleni. NC 
Lawrence M. Raines III. MI),. Chapel llill. NC 
Eileen M. Raynor. MD,. J.icksonville. II. 
Norman E. Sharpless. M.D,. Newton. M.A 
Tammy R. Spear, M.D.. Summert'ield. NC 
Eric S, Stem. M.D.. Fort Wayne. IN 
Theodore T. Thompson, M.D,. .Abingdon, V.A 
Loretta K, Tibbels, M.D,. Omaha. NE 
Paige C, Walend. MD,. Phoenix. AZ 
Lisa 1. Wang. M D,. Houston. T\ 
Bruin R Webster. MD,. Wilmington. NC 
William K. Westerkam. M.D., Coliimhia. SC 
Kirk I., Wooslev. MD,. Ch.irlotte. NC 
MehndaT, Wvatl. MI). Raleigh. NC 

CT.ASSOF IW4 
Number in Class: 153 
Percent Donors: 21,6'^^ 

Jonathan G Austin. Ml). Moiini I'lc.isanl. SC 

Laura H, Bachniann, M.I), and Kurt C B.kh 

mann. MD,. Birmingham. AL 

.Mary T. Bond. .M.D.. Fayelteville. GA 

Jane H. Brice, M.D., Chapel Hill. NC 

Marlene S. Calderon. MD.. Ypsilanii. Ml 

Peter T Chu. M.D . Fletcher. NC 

Lisa A. Ciillespie. M D . l.ithonia. GA 

Robin P B Hicks. .M.D., Newton Highlands. MA 

Chandra S Hollier, M.D.. Carol Springs. 11. 

William H Jones. M.D.. Charlotte. NC 

Carrie S. Kent. M.D.. Lenoir, NC 

Kenneth C. Lcnnon. M.D.. Greenville. S( 



Roy S Lewis. M D,. Houston. T\ 

Melissa M, Luiz. MD,. Chapel Hill. NC 

John L. Matthews. M.D.. Durham. NC 

Karen F, Mattocks. MD.. Columbia. SC 

Lucy S. Miller. M.D, and Robert Sean Miller. Jr. 

M.D. Cincinnati. OH 

Jacqueline H, Minis. Ml) and J, W hitman Minis. 

Ml). Winston Salem. NC 

l),iniel H. Moore. Ml). Ches.ipe.ike, VA 

Juha E, Norem-Cokei. Ml),. Favetteville. NC 

John B Patterson. MD . PhD . Winston-Salem. NC 

William L. Plyler, M.D.. Hendersonville, NC 

Claudia C. Prose, M.D.. Chapel Hill, NC 

Lisa A. Rietz. M.D., St. Louis. MO 

John W. Rusher, MD., Raleigh, NC 

Richard Scherczinger, M.D.. Cornelius, NC 

Nicholas B. Sliz. Jr. M.D.. Lawrenceville, TN 

Carolyn T. Spencer, M.D., Gainesville, FL 

Bristol R Winslow. MD . Durham. NC 

Juhe L, Wynne. MD,. Milhnocket. MH 

CLASS OF IW5 
Number in Cla.ss: 174 
Percent Donors: 24.1 T'c 

.Mich.iel D, Applegate. M.D.. Asheboro. NC 

Joshua E, Bernstein. M.D., Cambridge, MA 

Paul H. Bowman, M.D., Augusta, GA 

Peter A. Caprise, Jr.. M.D.. Chapel Hill, NC 

Christina L. Catlett. M.D.. Ellicott City, MD 

David A. Chesnutt. M.D.. Chapel Hill, NC 

Elizabeth C. Deterding. MD,. Summertleld. NC 

Andrea B Dickerson. .M D . Favetteville. NC 

Elisabeth K, Dipietro. MD,. Weston. .MA 

David B. Dorofi. M.D.. Norfolk. VA 

Dietrich A. Gerhardt. M.D., Waterloo. LA 

Richard Ryan Gessner. M.D and Sarah Young 

Gessner. M.D.. Charleston, SC 

Kathcnnc Meadows Harper. M.I), ,iiid Stephen A. 

Harper. MD,. Clemmons. NC 

Marcus T, Higi, M.D.. Tallahassee. Kl. 

John B, Holtzapple 111. M.D.. Eugene. OR 

Richard H. Jones, M.D., Patuxent River, MD 

Angela M. Keen. M.D., Salt Lake City, I'T 

Suzanne Lazorick. M.D.. Clayton, NC 

A. Kellett Letson 111. Ml).. Asheville. NC 

William D. Lyday II. .M.D,. Omaha. NF 

Brant K. Oelschlager. MD,. .Seattle. WA 

John W. Ogle 111, M.D., Palo Alto. CA 

Hitcn K. Patel. M.D.. Charlotte. NC 

Linda D. Pegram. M.D,. Philadelphia. PA 

Monica L. Piecyk. M.D. and John B Piecyk, 

M.D., Canton. MA 

Laura M, Robert. M.D,. Lynchburg. \A 

Paul D. Rosen. M D . New Voik. NY 

Wesley G. Schooler. .\l I) , Duiham. NC 

Susan K. Seo. .Ml). New York, N^ 

David R, Shaffer. Ml),. New York. NY' 

C.inil G. Shores. M.D.. Chapel Hill. NC 

D.ina L, Simpson, M.D , Charleston, SC 

\ni.iiida 1. Slater. MI).. Pittsboro, NC 

l< S Spies. Ml). Matthews, NC 

Jawal Suleman. M I) . Colunibia, SC 

John W Surles. M D . M,k Jesficld. NC 

Ketan K. Iriveih. Ml). Alex.indna. \A 

Kellv M. Waicus. Ml), Durham. NC 

Deidra I. Woods. Ml). Washington. DC 

CLASS OI I'f'lf, 
Number in Class; 15'> 
Percent Donors: 211. 1 ' i 

37 



Maa' Oregon Amaya. M.D. and Sharon Croom 
Amaya. M.D.. Mableton, GA 
Kathenne E. Barrett. M.D.. Raleigh. NC 
David K. Becker, M.D.. Chapel Hill. NC 
Andrea C. Best. M.D.. Culver City, CA 
Sara B. Beyer. M.D.. Matthews. NC 
Ann-Bndget D. Bird. M.D.. Durham. NC 
Cynthia J. Brown. M.D.. Waterhury. CT 
Christopher H. Chay. M.D.. Ann Arbor. Ml 
William J. Conner. M.D.. Dunn. NC 
Lorraine D. Comwell. M.D.. Carrboro. NC 
Robert M. Dums. M.D.. Christiansburg. VA 
Cory A. Dunnick. M.D.. Nashville. TN 
Joan E. East. M.D.. Asheville. NC 
Douglas K. Graham. M.D.. Highlands Ranch. CO 
Brian Earl Grogg. M.D. and Karen Lynne Grogg. 
M.D. Rochester. MN 
.lames A. Haaksma. M.D.. .'\sheville. NC 
Juhc A. Haizlip. M.D.. Chapel Hill. NC 
Kimberly J. Hamilton. M.D.. Durham. NC 
Chamette M. Huggins. M.D.. Washington. NC 
E. Allen Liles. Jr.. .M.D.. Durham. NC 
Michael H. Lowry. M.D.. Morehead City. NC 
Daniel E Maher. M.D.. San Diego. CA 
John E. Milko. M.D.. Myrtle Beach. SC 
David P. Miller. Jr. M.D.. demons.. NC 
Tracey E. O'Connell. M.D.. Durham, NC 
David N. Quinn. M.D.. Columbus, OH 
Lisa M. Roberts, M.D., Pittsburgh, PA 
JettVy P. Simko, M.D., Ph.D.. San Francisco. CA 
William T. Smith IV. M.D.. Durham. NC 
Carlos A. Vargas. M.D.. Eranklm. NC 

CLASS OF IW7 
Number in Class: 161 
Percent Donors: 41.(11- 

Eyal C. Altar. M.D.. Biookline. MA 

Henry C. Baggett III. M.D.. Anchorage, AK 

Ihre/ R. Bandukwala. M.D.. Atlanta. GA 
Michael L. Batten. M.D.. Philadelphia. PA 
,'\ndrew William Ba/emore. M.D. and 
.Anna Marlet Bazemore. M.D.. Cincinnati. OH 
Kimherly L. Beavers. M.D.. Chapel Hill. NC 
Kclurah C. Bell. M.D.. Kingsport. TN 
George M. Brinson. M.D.. Chapel Hill. NC 
Debbie A. Brown. M.D.. Southfield. MI 
Michael B. Brumback. M.D.. Atlanta. GA 
\Lirk D. Charlson. M.D.. Chapel Hill. NC 
Stephen V. Chiavetta III. M.D.. Rochester. MN 
Kathy N. Chism. M.D.. Knowille. TN 
Elizabeth C. Clark. M.D.. Portland. OR 
Raymond D. Cook. M.D.. Durham. NC 
Nicole M. D' Andrea. M.D.. Chapel Hill. NC 
Lance L. Davis. M.D.. Charleston. SC 
Charles S. Dietrich 111. M.D.. Honolulu. HI 
Carrie A. Dow-Smith. M.D. and Vincent C. 
Smith. M.D.. Pearland. T.\ 
Charles W. Eitrig. M.D.. Miami Beach. FL 
Janel R. Encamacion. M.D.. Springfield. MO 
Thomas W. Gansinan. M.D.. Indianapolis. IN 
Cathryn A. Geary. M.D.. Cincinnati. OH 
Bradley C. Gehrs. M.D.. Birmingham. ."XL 
Chandra S. Ghosh. M.D.. Atlanta. GA 
Michael Gill. M.D.. Ann Arbor. MI 
Leigh B. Goodwin. M.D.. Charlotte, NC 
Todd E Griffith. M.D.. Durham. NC 
Richard W. Hudspeth. M.D., Salt Lake City. L'T 
Srikant B. Iyer. M.D.. Cincinnati. OH 
Paul Harian Kartheiser. M.D. and .-Xmy Mane 
Lrsano. M.D.. Durham. NC 

38 



Andrew L. Katz. M.D.. Durham. NC 

Dawn E. Kleinman. .M.D.. Carrboro. NC 

Jennifer S. Klenzak. M.D. and Scott M. Klenzak. 

M.D.. Durham. NC 

Ramesh L. Krishnaraj. M.D.. Greensboro. .NC 

Kathryn A. Lee. M.D.. Etna. NH 

Cindi J. Leech. M.D.. Salt Lake City. UT 

Erica A Lyndrup. M.D.. New York. NY 

Donna B. McGee. M.D.. Horse Shoe, NC 

Leah R .Mc.Mann. .M.D.. Dupont. WA 

Jerry W. Mitchell. Jr.. M.D.. Pittsburgh. PA 

Dean S. Morrell. M.D.. Chapel Hill. NC 

Amy L. Mosher. M.D.. Chapel Hill. NC 

Jeffrey S. Moyer. M.D.. .Ann .Arbor. Ml 

Julia K. Nelson. M.D.. Durham. NC 

Brian S. OKelley. M.D.. Gainesville, FL 

John Charles Parker. M.D. and 

Heather M. Henderson. M.D.. Lexington. K'l' 

Joseph F Penta. M.D.. FPO. AP 

John K. Petty. M.D.. Portland. OR 

Sarah B. Philp. M D.. .Seattle. WA 

Jennifer E. Rhodes-Kropf .\LD.. New York, NY 

Austin S. Rose. M.D.. Chapel Hill. NC 

John R. Stephens. M.D. and Anne H. Stephens. 

M.D.. Durham. NC 

Julie C. Verchick. M.D.. Pinehurst. NC 

Lauren E. Wagner. M.D.. Chicago. IL 

Melanie P Walker, M.D.. Cincinnati. OH 

Lydia Ward. M.D.. Charleston. SC 

lllya L. Wilkerson. M.D.. Greensboro. NC 

Christopher R. Williams. M.D.. Bimiingham. AL 

Laura Clark Windham. M D.. Durham. NC 

CLASS OF IWS 
Number in Class: 152 
Percent Donors: 34.2% 
John G. Alley. Jr. M.D.. Carrboro. NC 
Christopher W. Baird. M.D.. Pittsburgh. PA 
Elizabeth R. Bates. M.D.. Berkeley. CA 
Michelle W. Beckham. M.D.. Concord. NC 
Dalliah M. Black. M.D.. Hillsborough. NC 
Jacqueline C. Chang. M.D.. Na.shville. TN 
Alan Cook. M.D.. Durham. NC 
Christopher C. Copenhaver. M.D. and 
Carol Anne Borack. M.D.. Rochester. NY 
Mary S. Crowder. M.D.. Greenville. NC 
James M. O. Culver. M.D.. Durham. NC 
Farr A. Curlin. M.D.. Chicago. IL 
Jason E. DeVente. M.D.. Greenville. NC 
William F. Durland. Jr.. M.D.. Maple Bluff Wl 
Jonathan E. Fischer. M.D.. Carrboro. NC 
Maxwell E. Fisher. M.D.. Nashville. TN 
Angela B. Gantt-Holliday. M.D.. Dublin. OH 
Kathy L. Gariand. M.D.. Chapel Hill, NC 
Barbara K. Gavin, M.D., Boston. MA 
Nichole D. Gner, M.D., Chapel Hill. NC 
Chad Gunnlaugsson. M.D.. Ypsilanti. MI 
Joshua L. Hardison. M.D.. Cumberland. Rl 
Paul M. Henderson. M.D.. Hendersonville. NC 
Michael S. Hoben. M.D.. Charlotte. NC 
Rebeccah A. Hoffman. M.D.. Monroeville. PA 
Travis C. Honeycutt. M.D.. Norfolk. VA 
Joseph T. Jenkins. M.D.. Chapel Hill. NC 
Traci A. Lamothe. M.D.. Charlotte. NC 
Miriam W. Lindrooth. M.D.. Northfield. IL 
Colby E. Mangum. M.D.. Winston Salem. NC 
Siobhan O'Connor. M.D.. Louisville. KY 
Robert S. Park, M.D., San Francisco. CA 
Stephen J. Phillips. M.D.. Baltimore. MD 
William G. Pittman III. M.D.. San Francisco. CA 



Caroline C. Prochnau. M.D.. Knoxville. TN 
James M. Schmidt. M.D.. Charlotte. NC 
Brian Shelley. .M.D.. .Albuquerque. NM 
Mona A. Sinno. M.D.. Waco. T\ 
Shelia D. Smith. M.D.. Richmond. CA 
Amy B. Stanfield, M.D.. Charlotte, NC 
Thomas E. Stephens. .M.D.. Asheville. NC 
William H. Sturgill III. M.D.. Jacksonville. NC 
Andrew J. Taylor. M.D.. Wnghtsville Beach. NC 
Stephan G. Thiede. .M.D.. Chapel Hill. NC 
Michael M. Walger. M.D.. Loma Linda. CA 
John W. Warner. M.D., Falls Church. VA 
Elizabeth S. Weinberg, M.D., Cincinnati, OH 
T Bnan Willard. M.D.. Columbia. MO 
Paul L. Winslow III. M.D.. Durham. NC 
Robyn K. Zanard. M.D.. Greensboro. NC 
.Adam J. Zolotor. M.D. and Karolyn Forbes, 
M.D.. Ann Arbor. MI 

CLASS OF I9W 

Number in Class: 133 

Percent Donors: 27.1 '^f 

Victor C. Archie. M.D.. Thousand Oaks. CA 

Eric D Bernstein. M.D.. Portland, OR 

Roben C. Bowen 111. M.D.. Charlotte. NC 

Stephen P Brackbill. M.D.. Chicago. IL 

Craig M. Bumworth. M.D.. Columbia, SC 

Peggy A. Byun. M.D.. Winston-Salem. NC 

H. Scott Cameron II. M.D.. Baltimore. MD 

Nicole Chaisson. M.D.. Saint Paul. MN 

John B. Chiavetta. M.D.. Rochester. MN 

Ellen C. Collett. M.D.. Morganton. NC 

Stanley R Dover, M.D., Winston-Salem, NC 

Robert A. DuBose. M.D.. Seattle. WA 

Carrie L. Dul. M.D.. Portland. OR 

S Sheppard Dunlevie. Jr. M.D.. Charlotte. NC 

Michelle E. Elisburg. M.D.. Kew Gardens. NY 

Lisa A. Flora. M.D.. New Castle. DE 

Robert G. Goodrich, M.D.. Chapel Hill, NC 

Lisa J. Harrington. M.D.. Providence. RI 

Angela L. Heider. M.D.. Chapel Hill. NC 

Winny W. L. Hung. M.D.. Providence. Rl 

Yewande J. Johnson. M.D.. Birmingham. AL 

Kevin J. Logel. M.D.. Salt Lake City. UT 

Marchi V. Lopez-Linus. M.D.. Chapel Hill. NC 

Ben M. Meares. Jr.. M.D.. Taylors, SC 

Brian H. Mullis. M.D.. Durham. NC 

Stephen F. Parsons. M.D. and .Alden M. Parsons, 

M.D. Chapel Hill. NC 

LeVonne G. Powell-Tillman. M.D.. Durham. NC 

Beth A. Renzulh. M.D.. Chapel Hill. NC 

L. .Allison Shivers. .M.D.. Nashville. TN 

Graham E. Snyder. M.D.. Manhasset. N\' 

Julia W. Tsang. M.D.. Chapel Hill. NC 

Harrison G. Tuttle. M.D.. South Burlington. VT 

A. Elizabeth Undenvood. M.D.. Salt Lake City. UT 

LaClaire Williams. M.D.. Tucson. ,AZ 

Enc S. Winer. M.D.. Maiden. .MA 

CLASS OF 2000 
Number in Cla.ss: 142 
Percent Donors: 4.2% 

Albert M. Anderson M.D.. Chapel Hill. NC 
Joshua W Knowles. Chapel Hill. NC 
Cathenne T. Lee M.D.. Chapel Hill. NC 
Zackary S. Moore M.D.. Chapel Hill. NC 
Jeffrey S. Mueller M.D.. Chapel Hill. NC 
Patrick A. O'Connell M.D.. Baltimore. MD 



MEDICAL ALLIED HEALTH SCIENCES 

GRADUATES 

Duane S. Anderson. Jr.. Siaunlon. \A 

Stephanie S. Baker. Car\. NC 

Lon E. Benn. Chicago. IL 

C\nthia P. Bodenheinier. Winston-Saleni. NC 

Ehzabeth .A. Bridges. .Atlanta. G.\ 

Doreen E. Clark. Raleigh. NC 

Cheri Courtright. Greensboro. NC 

Sidney S. Curn,. M.D.. Norcross. G.A 

Shan, n H. Davies. Little Rock. AR 

Susan H. Davis. Gibsonville. NC 

Jason M. Demon, Carrboro. .NC 

.Alice S. Duddy. Fi^mingham. M.A 

Laura H. Dudle\. Rocks Mount. NC 

Chnst\ S. Engle. .\Iaitheus. NC 

Bett\ B. Gast. Hickor\. NC 

Patrice E. Hardee. .Moms\ille. .NC 

Leslie C. Hawley. Corpus Christi. T.\ 

Michele M. Haywood. Columbia. SC 

Christin L. Hemmens. New Orleans, L.A 

Kathleen O. Hemdon. Raleigh. NC 

Carol Higgins-Gilmer. Chapel Hill. NC 

Catherine N. Humphrey. Bimungham. ,AL 

June S. Kenned\. Durham. NC 

Kimberls B. K.lug. .Menomonee Falls. WI 

Sheila R. McMahon. Raleigh. NC 

Cheryl E. Miller. Alpharetta. GA 

Joelle M. Roberson. WiUiamsville. N^■ 

Darlene K. Sekerak. Ph.D.. Raleigh. NC 

Patncia S. Sikes. Chapel Hill. NC 

Christopher S. Throckmorton. .Atlanta. G.A 

Kathenne P. Uomoto. Issaquah. W.A 

BASIC SCIENCES GRADL ATES 
Nils B. Ades. Ph.D.. Salt Lake City. LT 
Carolme H. .Aland. Ste\ensville. .\1D 
Patricia \\. Bair. .Marianna. FL 
Enc T Baldwin. Ph.D.. Kalania/oo. .Ml 
Christine A. Biron. Ph.D.. Pro\ idence. Rl 
Dehra D. Bloom. Ph.D.. Sun Prarie. WI 
Timoth\ J. Boiling. Wilmington. DE 
Joan P. Boone. Efland, NC 
Carl D, Bonner. Ph D. Durham. NC 
Su/anne C, Bullock. Blowing Rock. NC 
Janet P Burnham. Ph D . Raleigh. NC 
Robert (ilenn Butler. Escondido. C.A 
Karen E. Butler. Fredenck. MD 
Mary G. Cafiero. Richardson. TX 
Ian J Caley, PhD and Rebecca Pogue-Caley. 
Ph D . Chapel Hill. NC 
Ellen S. Cana\an. Cary. NC 
Shery 1 K. Camiak. Bismarck, ND 
Matthew E. Carrigan, Atlanta. GA 
Chia S. Chang. New Hyde Park, NV 
Kathry n K. Cheek. Columbus. GA 
Qiming Chen. Ph.D.. Horsham. PA 
Caroline M Christopher. Chapel Hill. NC 
Nancy W. Clark. Reston. VA 
Alison G. Comweil. Carrboro, NC 
Iimothy W. Corrigan. Charlotte, NC 
Debra K. Cowan. Chapel Hill, NC 
Victoria Z. Coward, Jacksonville, FL 
Merle M. Crawford. Hummelsiown. PA 
Dorothv L Daley. Wilmington. DL 
Robena M. Del.uca. Raleigh. NC 
Martha W. Easlcy, Amelia Island. FL 
Harriet H. Ellis, Wilson. NC 
.Amanda S. Englenh. Washington. DC 
Debra R. Ernst. West Bloomlield. Ml 



Leah S. Fletcher. Ph.D.. Geneseo, NY 

Carole J. Forloines. Kenneti Square, PA 

.Madeline H. Freeman. Greenville. SC 

Kathenne L. Fries. PhD . Atlanta. GA 

Jo Ellen F Gilbert. Jackson\ ille. FL 

JudithL. Glas, Oakdale. PA 

Charies A. Glick. Frederick. MD 

Robert P Gruninger. Chapel Hill. NC 

Heidi A. Harkins. Ph.D.. Ch.ipel Hill. NC 

Janet L. Harrill. Forest Cit\. NC 

Margaret P. Herbers. Silver Spring, MD 

Marcia W. Herbert. Virginia Beach. V.A 

Edna D. Hodges, Washington, NC 

Anne C. Huft. Ph.D. and Bruce E Miller. Ph D . 

Collegev ille. PA 

Diana B. Johannsen. Fredericksburg. \.A 

Brigid W. Johnston. Cary. NC 

Jane E. Jordan. The Woodlands, T.X 

Deborah W. King. Bremerton. WA 

Steven W King. Ph.D.. Florence. SC 

Susan .A. Klemm. Charlotte, NC 

Stephen B. Knisle>. Ph.D.. Birmingham, .AL 

Lauree M, Kruyer. Southern Pines. NC 

Roben A. Lerch, Ph.D.. Spring Valley. N1' 

Scott C. Li\ ingston, Erie. PA 

.Amy H. Lumsden, Arlington Heights, IL 

Earl E. Macy. West Plains, MO 

Melissa Maret, Ph.D.. Vardley. PA 

Celia C. McCartv. Alpharetta. GA 

William T McGivnev. Ph.D.. Rockledge. PA 

Tina W. McKeon. Atlanta. GA 

Jona P. Medlin. Raleigh. NC 

Beth E. Mileson. Ph.D.. Falls Church. VA 

Elzbieta M. Milewska. Saint Charles. IL 

Robert E. Moon. Fort Lauderdale. FL 

Susan H. Moore. Raleigh. NC 

Virginia W, Morton. Houston. T.X 

Karl F .Muster. D.D.S. and Carol Richtcr Muster. 

Ph.D., Champaign, IL 

Lauren B. Noble. Wake Forest, NC 

Elizabeth H. Pearsall. Rocky Mount. NC 

Dacia N. Pitzer, Cleveland. OH 

Dons T. Poole. Ph.D.. Chapel Hill. NC 

Gary E. Prillaman. D.D.S. . Mocksville. NC 

Tamaia R, Ritchie. Durham. NC 

Kristin R. Rogers. Princeton Junction. NJ 

Constance Rothermel. Ph.D.. Essex Ealls. \J 

James P. Ryan. Memphis. T.N 

Rachel J. Sanders. M.S.. Juneau. .AK 

Patricia Scronce. Woodbridge. \'.A 

J. .Michael Shenill. Danville. CA 

Rebecca A. Shirk. Ph.D.. Mahern. PA 

Susan S. Skeen, Elon College, NC 

Phillip G. Smith, Durham, NC 

Jennifer V. Smith. Ph.D.. West Chester, PA 

John N. Snouwaert, Ph.D., Chapel Hill, NC 

.Anne Steward Solari, Florissant. MO 

Sara J. Stit/er. Richmond. \ A 

Jean 1.. Stout. Saint Paul. MN 

Deborah II Strickland. Apc\. NC 

Pamela Perrs Sluhbs. I allbrook. CA 

Monroe J. Stutts III. Chapel Hill. NC 

Laura I. Tanner. Ph.D.. San I-rancisco. CA 

Stuart A, Thompson. Ph.D.. I-:\ans. GA 

Louisa B. Thompson. Roswell. G.A 

Kllen B. Troutman. Salisbury. NC 

Tsong-Tseh I sa\. Ph D . Orange. CA 

Cirace S. Tuckei. Dciiison. T.X 

Elizabeth F. Via. W insi,,n S.ilciii. NC 

Jeanne S. Wagner. Bcisc, 11) 



David E. Wain, Wilmington, NC 

Chervl H. Whelan. Louisville. KV 

Rebekah J. Wilkes. Lillington. NC 

Elizabeth C. Wilkinson, 'loungsv ille, NC 

Beverly A. Williams. Chapel Hill. NC 

Barnaby E. Wra\. Know ille. TN 

Albert G. Zimmermann. Ph.D.. Carrboro. NC 

F.ACL LT^l 

L.irr\ W. .Arnold. M.D.. Snow Camp. NC 
Stephen R. .Aylward, Ph.D.. Carrboro. NC 
Christopher C. Baker. M.D., Chapel Hill, NC 
Nancy P. Barnes. Severn. NC 
Stuan O. Bondurant. Jr.. M.D.. Chapel Hill. NC 
G.ir> n Bos. MD. Chapel Hill. NC 
Watson A, Bowes. .In. M,I),. Chapel Hill. NC 
H. Robert Brashear. ,|r.. M.I).. C hapel Hill. NC 
Dr. R. Alan and Mrs. Irene Brl(;j;anian. 
C hapel Hill. NC 

James A. Br\.in II. MD.. Chapel Hill. NC 
Joseph A. Butkwalttr. M.D.. Chapel Hill. NC 
John B, Buse. M.I),. Ph.D.. Chapel Hill. NC 
John 1) Bulls. Jr. MO. Duili.un. \( 
Robert C. Cefalo. .M.U.. Chapel Hill, NC 
Thomas V. Clancy. M.D.. Wilmington, NC 
Richard L. Clark, M.D.. Chapel Hill. NC 
William Lord Coleman. M.D.. Chapel Hill. NC 
Anna Marie Connolly, M.D.. Chapel Hill. NC 
Ernest Craige. M.D.. Chapel Hill. NC 
William J. Croimrtic. MD . Ch.ipel Hill. NC 
Floyd W. Denny, Jr.. M.D.. Chapel Hill. NC 
Robert F Devellis. Ph.D.. Chapel Hill. NC 
James F. Donohue. M.D.. C'hapel Hill. NC 
William Droegemueller. M.D.. Chapel Hill. NC 
Thomas M. Egan. M.D.. Chapel Hill. NC 
David E. Eifrig. Sr.. M.D,. Chapel Hill. NC 
Paul B. Farel. Ph.D.. Chapel Hill. NC 
Newton D, Fischer. M.D.. Chapel Hill. NC 
Charles G. Foskey. Chapel Hill, NC 
Jeffrey A. Frelinger. Ph.D., Ch.ipel Hill. NC 
Eric C. Frey. Ph.D.. Durham. NC 
VVilliam E. Garrett. M.D.. Ph.D.. Bahama. NC 
l.eon.ird S, Gettcs. M D . Chapel Hill. NC 
Robert N. (Jolden. M.I), and 
.Shannon C. Kenne>. M,l).. (hapel Hill. NC 
Joe W. (irisham. M.U.. Chapel IIIII. NC 
John J. Haggerly. Jr.. M.D.. Chapel llill. NC 
Joseph W Hall 111. Ml). Duih.mi. NC 
William I). Heizer. M.I)., (hapel Hill. N( 
Jeffrey 1.. Houpt. M.I)., (hapel Hill. NC 
Gregorv 1-, Hulka. Ml). Hillsborough. NC 
David G, K.uilm.in. MD . PhD . Chapel Hill. NC 
\MIIIam K. Kaufmann, Ph.D.. Durham. NC 
.Scott S. Kellev. Ml),. Chapel Hill. NC 
Thomas C. Keyseriing. .M.D.. Chapel Hill. NC 
Ernest N. Krayhill. M.D.. Chapel Hill. NC 
Jan A. Kylstra, M.D.. Chapel Hill. NC 
William E. Lassiter. Ml). Chapel Hill. NC 
H. R. Lesesne. M.D. Chapel llill. \C 
Kcnnelli J 1 evin. M I ). (hapel llill. NC 
Jelliev A l.icbeiiiiaii, \I I) . ( li.ipel Hill, NC 
( arol N. I.ucas. Ph.D.. (hapel llill. N( 
All.in A M.ihhie. M 1). Ch.ipel Hill, \( 
Elizabeth S. Mann. M.D.. (hapel llill. N( 
Stanlev J. .Martmkoskv. Ph 1) . Chapel Hill. NC 
Campbell W .Mc.Mill.in. Ml). Chapel Hill. NC 
D.ivul I \leiien. M D. Piiishoio. NC 
Anilinnv ,\ Mevei. Ml), Ch.ipel Hill. NC 
.Melanie Mintzei. Ml) .Ch.ipel Hill. NC 
Don K- Nakavama. Ml). R.ilcpjh. NC 

39 



Christian E. Newcomer Ph D.. Chapel Hill. NC 
Terry L. Noah. M.D., Carrboro. NC 
David A. Ontjes. M.D.. Chapel Hill. NC 
Anihony N. Passannante. M.D.. Chapel Hill. NC 
Edward R. Perl. M.D.. Chapel Hill, AC 
David R. Perry. Chapel Hill. NC 
Thomas D. Petes. Chapel Hill. NC 
Arthur J. Praiige. Jr. M.D.. Chapel Hill, NC 
Milton D. Quigless. Jr. M.D.. Raleigh. NC 
Kenneth G. Reeb, M.D., Chapel Hill, NC 
Desmond K. Runyan.M.D., Chapel Hill. NC 
Robert S. Sandler. M.D.. Chapel Hill. NC 
James H. Scatliff. M.D.. Chapel Hill. NC 
Nicholas J. Shaheen. M.D. and Amy W. Shaheen. 
M.D.. Chapel Hill. NC 
George F. Sheldon. M.D.. Chapel Hill. NC 
Sidney C. Smith. Jr. M.D.. Chapel Hill. NC 
Brian C. Stabler, Ph.D., Chapel Hill, NC 
Chuck Stone. Chapel Hill. NC 
Catherine A. Taylor. M.D.. Chapel Hill. NC 
Colin G. Thomas, Jr., M.D., Chapel Hill. NC 
Michael D. Topal. Ph.D.. Chapel Hill. NC 
Charles M. Van Der Horst. M.D.. Chapel Hill. NC 
Judson J. Van Wyk. M.D.. Chapel Hill. NC 
.Mahesh A. Varia. M.D.. Chapel Hill. NC 
Mark C, Weissler. .\1.D.. Chapel Hill. NC 
James R. While. Ph.D., Chapel Hill. VC 
Clarence E. Whilefield. Chapel Hill. NC 
J, Kenneth Whitt. Ph.D.. Chapel Hill. NC 
Frank C. Wilson. M.D., Chapel Hill, NC 
Richard V. Wolfenden. Phi).. Chapel Hill, NC 
James R. Yankaskas. M.D. and Bonnie C. 
Yankaskas Ph.D.. MPH. Chapel Hill. NC 

IIOL'SE.STAFF 

Kiehard C. .Andrinjja, M.D.. (ireensboro. NC 

Ray M. Antley. M.D.. Morganton. NC 
William B. Applegate. M.D.. Winston-Salem. NC 
James W. Asaph. M.D.. Portland. OR 
Thomas .\1. Bashore. M D.. Durham. NC 
Stephen N. Becker. M.D,. Libhy. MT 
Jeffrey P. Bonize. M.D.. Bryn Mav\r. PA 
Thomas A. Brackbill. M.D., Greensboro, NC 
Bruce R. Brodie. M.D.. Greensboro, NC 
Robert A. Brown, M.D.. Fort Myers. FL 
Wallace D. Brown. M.D.. Raleigh. NC 
George F. Brumback. M.D.. Greensboro. NC 
Edwin L. Bryan. M.D.. Greensboro. NC 
Robert V. Buccini. M.D.. Greensboro. NC 
Kenneth A. Buddendorff III. M.D.. Mobile. AL 
William R. Bullock. M.D.. Charlotte. NC 
Allen E. Cato. Jr. M.D.. Durham. NC 
G. Raybum Cheely. M.D.. Raleigh. NC 
Robert Che\alier. M.D.. Charlottesville. VA 
.Arsenio O. Cordoves. M.D.. Miami. FL 
Thomas P Cornwall. M.D.. Durham. NC 
•Stanley C. Cox HI, M.D., Southern Pines, NC 
Barbara A. Crockett. M.D.. Durham. NC 
John T Cumes. M.D. and Cheryl A. Viglione. 
VI.D. Greensboro. NC 
Frederic G. Dalldorf. M.I), and 
Joanna S. Dalldorf. M.D., Chapel Hill, NC 
Marsha L. Davenport. M.D.. Chapel Hill. NC 
A. Joseph D'Ercole. M.D.. Chapel Hill. NC 
Wayne R. Detorres. M.D.. Mahwah. NJ 
Donald G. Detweiler. M.D.. Raleigh. NC 
Douglas R. Dirschl. M.D.. Chapel Hill. NC 
Diane M. Duffy. M.D.. Graham. NC 
Michael F Durfee. M.D.. Raleigh. NC 
Richard Essner. M.D.. Los Angeles. CA 

40 



Lisa P. Ferran. .M.D.. Durham. .NC 

Catherine A. Fomeris. M.D.. Chapel Hill. NC 

Charles E. Frederick. M.D.. Greensboro. NC 

James C. Garbutt. M.D.. Pittsboro. NC 

Larry D. Grubh. MD.. Florence. SC 

Todd H. Hansen. .M.D.. Asheville, NC 

Frank J. Haraf, M.D., Louisville, TN 

Carl R. Hartrampf. Jr. M.D.. Atlanta. GA 

Glenn B. Hays. M.D.. North Fort Myers. FL 

Xaver F. Hertle. M.D.. Greensboro, NC 

Michael A. Hill. M.D.. Durham. NC 

Peter J Holland. M.D. and Donna S. Holland. 

.\I D. Boca Raton. FL 

Robert R. Huntley. M.D. and Joan t . Huntley. 

Ph.D., t hapel Hill, Nt 

Burton R. Hutto. M.D.. Chapel Hill. NC 

Harold N. Jacklin. M.D.. Greensboro. NC 

.\li Jarrahi, M.D., VVinston-.Salem, NC 

Robert B. Johnson. M.D.. Gary. NC 

Thomas L. Johnson. M.D.. Inglewood. CA 

J. Jeff Johnson. M.D.. Paducah. KY 

F. Douglas Jones. M.D.. Greenville. NC 
Raleigh O. Jones. Jr., M.D. and Janine C Jones. 
M.D.. Nicholasville. KY 

Hisashi Kajikuri. M.D., Monterey, CA 
Jeffrey D Kal/. .\1.D . (iicensboio. NC 
Moyra E, Kilell. Ml).. Chapel Hill. NC 
Jonathan S. Krauss. M.D.. .Augusta. GA 
Walter L. Lamar, M.D.. Tulsa, OK 
Halcut C. Lawrence HI, \LD., Asheville, NC 
Randolph L. Lee. M.D.. Apex. NC 
Steven Lipper. M.D.. Chapel Hill. NC 
Frank A. Loda. M.D.. Chapel Hill. NC 
Dr Jane L. Madison. Chapel Hill. NC 
H. Rayinond Madry. Jr. M.D., Raleigh, NC 
Bruce T. Malenbauiri, M.D., Durham,, NC 

G. Philip Manire, Ph.D., Chapel Hill, NC 
Peter J. Massicott. M.D.. Boston. MA 

Al.m H. .\l.itsumoto. M.D . Charlottesville. VA 
Charles R. McAdams. Jr. M.D., Charlotte. NC 
James (.',. MeClure, >LD., Memphis. TN 
W. Benson McCutcheon, Jr., \LD., Durham. NC 
William T. McKinney. Jr. M.D.. Madison. Wi 
Morton Meltzer. M.D.. Cameron. NC 
Steven L. Mendelsohn. M.D.. Asheville. NC 
James J. Murphy. M.D.. Arden. NC 
Mark E. Murphy, M.D.. .Savannah. G.A 
Keith A. Nance. M.D.. Raleigh. NC 
Charies L. Nance. Jr. M.D.. Wilmington. NC 
John L. Nehil, M.D., Louisville. KY 
Richard A. Niles. M.D.. Lynchburg. VA 
Margaret R. Nusbaum. D.O.. M.PH.. Chapel Hill. NC 
John W. Oglesby. M.D.. Nashville. TN 
Frederick H. Opper. M.D.. Wilmington. NC 
Louis V. Paciho. M.D.. Leeds. MA 
Linn H. Parsons. M.D.. Winston-Salem. NC 
Joseph F Patterson. Jr. M.D.. Chapel Hill. NC 
George H. Pierson. Jr. M.D.. Greensboro. NC 
Cedric W. Porter. Jr. M.D.. Asheville. NC 
William 1. Proctor. M.D.. Raleigh. NC 
Rupa C. Redding-Lallinger. M.D.. Chapel Hill. NC 
Hal J. Rollins. Jr. M.D.. Greensboro. NC 
Roland E. Schmidt. M.D.. Chapel Hill. NC 
Michael S. Schur. M.D.. Satellite Beach. FL 
Stephen B. Schuster. M.D., Greensboro. NC 
Ronald P Schw.iiv, M D . Raleigh. NC 
Stephanie .A. Skolik. M.D.. Huntington. WV 
Bryan W. Smith. M.D. and Mary F Smith. M.D.. 
Chapel Hill. NC 
John J. Solic. M.D.. State College. PA 



Liang Y. Soo. .M.D. and Dixie L. Soo. NLD.. 

Chapel Hill. NC 

Ernest B. Spangler. Jr.. M.D.. Greensboro, NC 

Mary C, Steuterman. M.D.. Greensboro. NC 
Thomas NL S«antkovvski, \LD.. 
Southern Pines, NC 

Robert V. Sypher. Jr. M.D.. Greensboro, NC 
Dianne W. Trumbull. M.D.. Morgantown. WV 
George L. Wallace. Jr. .M.D.. Maninsville. VA 
Turin P. Walters, M.D., Huntington, W V 
Brent W. Weston. M D.. Durham. NC 
Camngton W. White. .M.D.. Durham. NC 
Kenneth S. White. M.D.. Wilmington. NC 
Robert W. Whitener. M.D.. Greensboro. NC 
Frances K. Widmann. M.D.. Chapel Hill. NC 
Jeffrey L. Wilson, M.D.. (ilasgow, KY 
George T. Wolff. M.D.. Greensboro. NC 
Lucas Wong. M.D.. Temple. T\ 
H. Linton Wray. M.D.. Che\y Chase. ,MD 
Peter R. Young, Sr., M.D., (Jreensboro, NC 
Nakhleh P. Zarzar, M.D., Raleigh. NC 
.Mary E. Zelcnik. .\LD.. Clifton Forge. VA 
Thomas .A. Zirker. ML).. Greensboro, NC 

Ph.D. GRADL.ATES 

Phyllis G. Andrews. Ph.D.. Durham. NC 

Linda M. Boland. Ph.D.. Woodbury. MN 

Philip Brooks, Ph,D., Bethesda, MD 

Ronald K. Charlton. Ph.D.. Jacksoinille. FL 

Haroutune Dekirmenjian. Ph.D.. Knowille. TN 

Lori Ann Dostal. Ph.D.. Brighton. Ml 

David Joel Edwards. Ph.D. and .Mary Hemng 

Edwards. M.D.. Pittsburgh. PA 

Janet L. Evans. Ph.D.. Stockton. NJ 

Charles C. Finley. Ph.D. Chapel Hill. NC 

James C. W. Finley. Ph.D.. Cleveland. OH 

Beatnce Hughes- Werner. Ph.D.. Chapel Hill, NC 

Warren M. Kati, Ph.D., Gurnee, IL 

Tec-Ping Lee. Ph.D.. Williamsville. NY 

.Michael J. Leiivelt. Ph.D.. Sun Praire. Wi 

David P Lewis. Ph.D.. Pearl River. NY 

David M. Mottola. Ph,D.. Tampa. FL 

Mary Ella M. Pierpont. Ph.D.. Samt Paul. MN 

Derek T. Puff. Ph.D.. Somersville. MA 

Bonnie B. Punske. Ph.D.. Sandy. UT 

.Mariorie S. Read. Ph.D.. Durham. NC 

Robert A. Schwartzman. Ph.D.. Gaithershurg. MD 

Peter R. Shank. Ph.D.. Rumford. Rl 

Charles J. Viviano. Ph.D.. Beacon Falls. CT 

Michael D. Waters. Ph.D.. Chapel Hill, NC 



President's 
Letter 



The UNC Legacy 

Se\L'ral weeks ago. iii\ wcirkdas was oil tn 
a tiHigh start. E\er\()nc was show ing up fur 
his appointineni. This led. iiicxorably. tn ni\ 
falling tiirther and further hehind schedule. 
Fifteen minutes should be enough lime lor an 
internist tti see a follow-up patient, but that 
span is sinipl\ not realistic for some. On this 
particular da>. nian\ of m\ challenging 
patients were arranged in rapid - a lelalise 
term - succession. Most phvsicians. except 
perhaps for those in the most rarefied sjiecial- 
lies. can relate to m_\ plight. 

M\ first three patients that da\ arrived 
bearing carefull\ recorded lists of iheir 
concerns. Despite the w rillen plea posted in 
m\ waiting room — "'No Lists" — m\ pa- 
tients gleefulK disregarded m\' sign. Follow- 
ing instead the ad\ice in /'rcvciiiicn 
maga/ine on how to get the most out ot their 
\ isit w ith the doctor. the_\ honed a detailed 
outline of the past month's problems. The\ 
should ha\e read Medical Economics which 
brands such patients as "difficult." the type to 
be axoided whenexer possible. From either 
perspecine. the dreaded Lists guaranteed 
that the \ isiis were not going to be neatl) lieil 
tip in \5 minutes I 

.Also conspiring to keep me off schedule 
were several patients with a chief complaint 
of "weakness."" Known all too well b\ iii\ 
colleagues in primary care, weakness ii\als 
constipation as the most per\asi\e nialad\ 
ever lo afflict humankintl. yet the medical 
literature is nearlv silent on the subject. I here 
are several variants .Among the most com- 
mon are: "'Doc. I |usi ain't got no energy." 
.And. ".\I\ gel up and go done got up and 
went." Occasionally, after ruling out a lew of 
ihe common potential underlv ing diagnoses. 
1 tlaie lo ascribe some sv mptoms to the aging 
process, iiul this can be a less-than-gracelul 
lorax into a Ihornx dialogue. "L\e never had 
ihis problem before." the patient insists. 
"But vou've never been 86 before either. ' 
I respoiul |ilainly if not bluntly. ,At this 
point. I have been in the room lor 
2> minutes and mv neallv -cratled otiice 
schedule 



IS a distant memorv. .Such was mv biisv 
Nh>ndav morning back in .Atigust. 

What has anv of this to do w ith the L^NC" 
Medical .Alunini Assiiciation '.' Perha|is this: 
Ihe frustrations of the morning got me thinking 
about mv role w ithin the larger medical com- 
munitv. .Someone has to he first to wade 
through the vast bodv ol patient complainis. 
The primary care physician has the responsi 
bility to discern, for example, the pedestrian 
age-related "weakness" from the "weakness" 
of iri>n deficienev. hv polhv ronlism. or 
diabetes. Others, such as L'niversilv lacuhv. 
may serve bv spending their entire careers on 
viral hepatitis or glaucoma, becoming 
authorities w ithin a narrow subject area. 
Even administrators play a ke\ pari in 
providing timelv services in a manner besi 
suited to the patient's needs. 

So It is too with UNC School of Medicine. 
We all occupy an important cog in the 
machinery of lop-tlight patient care. Acade- 
mics teach, conduct research, and treat rare 
diseases. Dean Houpt deals w ith the critical 
niacro issues of funding, the Legislature, 
phx sical plant needs, and departmental leail- 
ership. Sludenls bring energv and enlhusiasm 
into the mix. 

We alumni contrihule as well. ('omprisei.i 
mostly of physicians in private practice, we 
prov ide ihe btilk of medical care. Irom our 
practices can come a stream of patieiil lefer- 
rals. .Also, regular financial support has a 
meaningful inipact. and this has been ]iarlic- 
ularlv true in recent years. F^ach of us has an 
opportunity and an obligation to parlicipale 
in the affairs of our alma mater. After all. it 
was as students, many vears ago. that we first 
became piotid members ol the I'NC" lamilv. 
Let us all cherish this sioried legacv. and 
responil in kind 





CME/Alumni Calendar 

Sovemher 1 7, 2000 — The Friday Center. Chapel Hill 

Psychuilry Across the Ages; 5lli Annual Update 

Sovemher IS, 2000 — The Friday Center. Chapel Hill 

17th Annual George C Hani Symposiuni 



Estate Planning Notice 

Many individuals would like to make a major gift 
to the UNC medical center, but cannot commit 
current assets for such a purpose. Through a will, 
however, anyone can make a more significant gift 
than they might ever have thought possible by 
designating a specific sum, a percentage, or the 
residue of their estate for the benefit of the medical 



December I. 2000 — The Friday Center. Chapel Hill 

Domestic Violence Conference 

Deeeinher 2. 2000 — The Friday Center. Chapel Hill 

A Multidisciplinary Approach to Ksophageal Disease 

January IS-19. 2001— The Friday Center. Chapel Hill 

Challenges in Geriatric Practice: I2lh Annual ("onlerencc 

January 31. 2001 - Chapel Hill 
Student Research Day 2001 

April 27-2S, 2001 - Chapel Hill 

Spring Medical Alumni Weekend 

For more information about CME courses, contact the OtTicc 
ot Continuing Medical Education at (41'*) 9(i2-21 IS or loll 
tree through the Consultation Center at (800) 852-6264. To 
contact the Alumni Affairs Office, call (919) 962-6786 or 
email medical_ahimni(n nied.unc.edu 



To provide a bequest, sinq)ly include a paragraph 
in your will naming The Medical Foundation of 
North Carolina, Inc. as a beneficiary. For example: 

"I give, devise and bequeath (the sum of$ 

or ( % of my estate) or (the residue of 

my estate) to The Medical Foundation of North 
Carolina, Inc., a 501(C)(3) created to maintain 
funds for the UNC medical center with principal 
offices located at 880 Airport Road, ChapelHill, 
North Carolina." 

This language creates an unrestricted bequest for 
use by the medical center when and where the need 
is greatest, or you may specify that your gift be 
used for a particular purpose. 

For further information on bequests, contact 
Jane McNeer at (919) 966-1201, (800) 962-2543, 
orjmcneer@email.unc.edu. 



Nimprofit Organization 

U.S. Postage 

PAID 

Chapel Hill, NC 
IVrniil No. 24 



PERIODICALS DEPARTMENT^ 
HEALTH SCIENCES LIBRARY 
CB 75B5 ^ ^ 

CAROLINA CAMPUS 7585