jCI
Dean's
Page
During a recent lunch with
medical student leaders, they
described several programs
they are developing to
improve the delivery of health care to
North Carolina's rapidly growing Latino
population. I am proud that our students
are continuing our school's tradition ot
creating new programs to meet communi-
ty needs. 1 asked Dr. Cheryl McCartney.
Executive Associate Dean lor Medical
Education and Dr. Georgette Dent, Asso-
ciate Dean for Student Affairs, who
mentor and support these leaders, to
describe the student initiatives below.
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In the past 3,'i years. Latinos have
become the kirgest immigrant group to the
Lhiited States: in North Carolina, the
Latino population increased 94.7 percent
during the 199()s. Although our state's
Latinos have diversified their employ-
ment from rural farm work to jobs in
urban construction and hospitality, this
population remains in the ranks of low
wage earners who face language and
cultural barriers to our state's health care
system. Four medical student organiza-
tions are addressing these issues: Spanish-
speakers Assisting Latinos Student
Association (SALSA), the Student Health
Action Committee (SHAC), Prevention
in ACTion (PACT) and the International
Health Forum (IHF).
SALSA was organized in 1997 by
three medical students: Marchi Lopez-
Linus ('99). Romulo Colindres (MS4) and
Suzanne Strandhoy ('99). The initial 20
members provided Spanish-language
interpreter services to the maternity and
well-child clinics at the Chatham Countv
Health Department in Pittsboro and our
local student-run SHAC clinic. SALSA's
current 80 members also serve the Wake
County Health Department's clinics
in Zebulon and Fuquay-Varina. UNC
Hospitals and the SHAC health-care
booth at the annual fair, hi Fiesta del
Pueblo. Dr. Alan Cross (adolescent medi-
cine) is the faculty adviser for SALSA and
this year's co-coordinators are Vaishali
Gupta (MS2) and Keith Kocher(MS2).
The SHAC Clinic, located in
Carrboro, is the oldest student-run, free
health care clinic for indigent patients in the
United States. SHAC's patients now
include a significant number of Latinos.
SHAC co-coordinators this year are David
Yale ( MS2) and Eric Wolak ( Nursing '(K)).
The faculty adviser is Dr. Adam Goldstein
(family medicine).
The IHF discusses international
health issues and promotes opportunities
for medical students to study abroad.
Recently, interest in research and service
projects in Spanish-speaking countries
resulted in students traveling to Costa
Rica. Honduras, Bolivia and Mexico.
Funded by our school's foreign fellow-
ship grant or by loans, students have
improved their Spanish language skills
while conducting supervised projects.
This year's IHF co-presidents are Todd
DeVries(MS2), Matthew Foster (MS2)
and Alan Schulman (MS2). Caroline
Stuck, deputy director of the Office of
International Affairs, is the IHF faculty
sponsor.
PACT students focused on migrant
health issues this fall. With support from
the UNC Program on Prevention and the
Wake County Health Department,
students were on the front lines of preven-
tion in the free clinics for these Latino
workers. Rachel Reisner and Miriah
Teeter (both MS2, PACT co-presidents)
organized groups that prepared culturally
sensitive, Spanish language curricula about
prevalent health problems of the communi-
ty such as diabetes, hypertension, green
tobacco illness, sun exposure and dehy-
dration, pact's faculty adviser is Amy
Ward. Program on Prevention co-direc-
tors are Drs. Russ Harris and Linda
Kinsinger (internal medicine).
Medical student enthusiasm for
improving Spanish fluency has galva-
nized co-presidents of our second-year
class. Heather Crou.se and Rebecca Sands,
to coordinate the development of a
medical Spanish course for intermediate
speakers. Internist and co-director of
Introduction to Clinical Medicine,
Dr. Marco Aleman, will direct this course,
emphasizing the language skills needed to
interview and examine patients. Associate
University Provost Ned Brooks, who has
supported the health affairs interdiscipli-
nary Spanish course. La Charla. has fund-
ed the initial development of the course,
and Dean Houpt will continue
the funding.
Students discussed the creation of
a special clinical track for those who want to
develop their Spanish skills and cultural
competency. Students could choose to
complete required clinical course work in
selected communities with a significant
Sp;uiish-speaking population.
Medical Alumni
Association Officers
President
Gordon B. LeGraiui. MD "65
Riilcl,i;li
President-Klect
Paul E. Viser. MD 84
Cliiiron
Vice President
Thomas J. Kooiit/. MD 66
\\'iii.\t(iihSii/ciii
Secretar\
Ralph L. Wall Jr.. MD"7X
WlnsldihSiili'Di
Treasurer
William .M. Hemdon. Jr.. MD "XI
Chaiionc
Editorial Staff
John W. Stokes
\hc President. Public Affairs &
Markctiiv^
Debra Pierce
MciiKf^iii'^ F.diuir
Leslie F. Lang. Melissa Matson. Karen
Slinnetord. L\nn Woolen
Cdiurihiiiin'j. \\ riuis
Jon Roltel (pi:. I I )
Bill Reaves (pg. 12)
Slarlyn Comhs (pgs. 21. 22 1
Don MacKen/ie (pg. 22)
Pluiid'^niphcrs
The Mediial Alumni liiillciin is published lour nines
annually by ihe LNCrhapel Hill Medical .Alumni
Association. Chapel Hill. NC 27.^ 14 Postage is paid
by Ihe non-profit asstKiation through L'.S. Postal
Permit No. 24. Address correspondence to the editor.
OfTice of Medical Center Public AITain.. .School ol
Medicine. CB#7WK). rjniversily of North Carolina.
Chapel Hill. NC27';i4.
Medical Alumni
BULLETIN
School of Medicine, I niversity of North Carolina at Chapel Hill
Contents
Features
MissniiiariL's lit the Medical Type
->,
Building .An Acadoniic Medical Center
....6
....<S
.SiitgeiA StLidents Create Hugh Willianison Society
Cuban Pediatrics Patient Takes International .-Xdx enlure
At 97. He Stares at Scars So Others May Breathe
LINC Stud\ Points to Chroniosonie Site ot .-Xutisin Gene
Alumni Protlle: Frank Huyler. MD '9.^
....9
..Id
..i:
..14
..IS
..2(1
..24
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Alumni Weekend
Departments
...Inside Fn)nt C
Ne\\ s Briets
..n
Facultv Notes
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Keseaich Briets
Piesiclenl's Letter
Inside Back C
CMI-:/Alumni Calendar
BackC
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liuikling projc'clsllic Schnol nl \K-iIk iiic i.nrivnll\ li.is uiidri consiiiK in
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11 Ilk- loiinclalioii
Ills iikIiuIccI in ph;
News
Briefs
UNC now home to new
nutrition research center
To help reduce the staggering toll
of unnecessary illness and premature death
associated u ith chronic disease and to
understand better the links between such
diseases and nutrition, the National Institutes
of Health chose L'NC as home of the nation's
newest Clinical Nutrition Research Linit.
"In the next five years, we'll receive S4.7
million from NIH to establish and operate
this unit." said Steven Zeisel, MD. PhD.
chair of nutrition for the schools of medicine
and public health and director of the new
center
"Our central goals will be to enhance the
speed at which new laboratory discoveries
are used in population-based and clinical
research, to make suic that the education of
health professionals includes nutrition and
to help people learn how they can improve
their diets to stay healthy." he said.
UNC will be one of only seven such units
in the United States. Others are at Harvard.
Washington University in St. Louis and the
universities of Chicago. Washington at
Seattle. Southern Alabama and Colorado at
Denver.
For more infonuanon. sec hitp.Hwww.
iiiu .cilii ncus neasM-'rviuniv zeisel^ KU.'fy
y.hliii.
Program on Health Outcomes
receives $2 million grant
UNC's Program on Health Outcomes
w ill receive nearly $2 million from the
federal government to create a Center for
Education and Research on Therapeutics
that v\ ill develop innovative education and
research efforts focusing on new and exist-
ing drugs and devices used in pediatric care.
The new center, is funded by a three-year.
$1.98 million grant from the Agency for
Health Care Policy and Research
(AHCPR). part of the U.S. Department of
Health and Human Sen. ices.
Carolina's newest research addition is
one of four centers for education and
research on therapeutics (CERT) created
nationw ide to boost the positive impact on
patient care of medical products — drugs,
biologies and medical devices — to reduce
the human and economic toll of inappropri-
ate use.
flNC researchers will focus on impros -
ing the health of children and adolescents.
Potential research areas include therapeutic
drug monitoring in HIV-infected children,
drug metabolism, vitamin D-deficient rick-
ets, asthma care, attention deficit-hyperac-
tivity disorder and adverse dnig reactions.
For more information, see liltp:/ nruw.
itih .ediil news! newsserrl unir^ sphi)92W^ .
him.
Adolescent mothers to
benefit from new grant
UNC's schools of medicine and public
health have received more than S 1 .5 million
from the Robert Wood Johnson Foundation
to support nurse home-visiting efforts that
help first-time, low -income adolescent
mothers and their new boms.
The funds are part of a three-year.
SlO-million grant awarded to the Children's
Hospital .Association of Denver to support
such efforts in 40 communities nationwide.
The grant will help establish a national
center for the home-nursing program at the
University of Colorado and a regional
center to be managed by the UNC School of
Public Health's North Carolina Institute
for Public Health. In the next three years,
the centers will train nurses and provide
support to implement a network of
programs in the communities.
The program provides in-home services
during pregnancy and the first two years of
a child's life. During weekly or biweekly
\ isits. nurses help expectant and new
mothers improve their knowledge of child
health and development, build parenting
skills and guide personal decision-making
about employment, substance abuse and
future pregnancies.
"The nurse home-visiting services
promote health in all areas: physical,
mental, emotional and social." said
Terrence Kenan, special program consul-
tant at the Robert Wood Johnson Founda-
tion. "This program provides young.
low -income mothers v\ ith crucial instruc-
tion, care and support that they might not
otherw ise receive."
New procedure offers
alternative for nasal surgery
An ear, nose and throat doctor at UNC is
using a new technology already proven
successful in treating snoring to provide a
less expensive, relatively pain-free alterna-
tive to traditional nasal obstruction surgery.
"This nonsurgical procedure, called
somnoplasty. could change how we're
doing things," said Wendell Yarbrough,
MD, assistant professor of otolaryngology,
w ho divides his time between head and
neck cancer research and clinical duties.
"The technology was first approved for
treating snoring, which is treatment of the
palate. It's exciting that another innovative
use of the technology has been approved."
SomnoplastN delivers radio frequency
energ\ through a needle, w hich. in the
treatment for snoring, is put underneath
the lining of the mouth.
"It creates a scar that, as it fonns. tightens
up the palate and decreases the volume and
intensity of snoring," Yarbrough said. "The
procedure is relatively pain-free — patients
might need to take some Motrin or Tylenol
immediately but narcotics for seven to 10
days are unnecessary. It's also more conve-
nient and less expensive because it can be
done in a physician's office and the patient
can be back at work the next day.
For the complete story, see littpillwww.
unc.edu!ne\\slne\vssenircsearchlyarhr(ni3
lOOIW.Iitm.
Correction
In the Summer 1999 Medical Alumni
Bulletin, we printed a New s Brief titled
"Womack Society Honors Plastic Surgeon."
We inadvertently failed to credit Carl R.
Hartrampf Jr.. MD, with commissioning,
funding and donating the portrait of Erie E.
Peacock Jr.. MD. JD. We extend our
apologies.
Missionaries of the Medical Type
By Melissa Matson
F.dihtr' s note: Manx i SC plnsiciaiis
inivcU'd (.ihroiid this past xcui. This artnlc
is not iiucndcd to hcamipirhcnsivc-
When most people think ot missions.
the\ think of something religious
in nature. But that's only p;ul of the
definition. Webster defines a mission as
"a sending out to perfomi a special sen ice."
.And that special ser\ ice can be anything —
political. scK'ial. medical orothen\ ise.
Here at UNC. we ha\e a hislor\ of
leaching the next generation i)f doctors. We
also ha\ e a histor\ of sharing our expertise
w ith other doctors around the state and the
country. For some UNC physicians, that
mission translates into traveling to less
tortunate countries to train local physicians
and pro\ ide medical services to local
people.
Follow ing are the sti>ries of a few \\ ho
ha\ e gone on medical missions this y ear
Helping children in Venezuela
This September. James Fletcher.
MBBS. clinical associate professor of
anesthesiolog\. and Robert Valle\'. MD.
associate professor of anesthesiology and
pediatrics, went to Maracaibo. Venezuela
with Rotaplast International'. They were
there 1 2 days.
On the first day. the team of fi\'e
surgeons and six anesthesiologists screened
ISO pediatric patients prior to surgery.
Then, during the next six days, the team
operated on 16.^ patients to repair cleft lips,
cleft palates or both. Fletcher and Valley
each pro\ ided anesthetic ser\'ices to five or
six children per da\.
As in the case of most medical mis-
sions, thev brought their ow n equipment
and supplies along w ith them, then set up
tor clinic and surgery in the local children's
hospital. Fletcher said of the facilities. "The
hospital lackeil much of the equipment that
we see around American hospitals, but our
hosts still had a good infrastructure for us lo
plug into. I learned sou can achiese a whole
lot w ith few resources."
ValleN agreed. 'It was much easier
than 1 expected to maintain an excellent
standard of care in a less-advantageil health
care facility." he said. "All it took was a
little ingenuity and a great team."
"The whole trip was intense." said
Fletcher "To see children traiisfomied from
social outcasts because of facial defoniiities
to socially acceptable was ama/ing. The
parents were indescribably happy to ha\e
their children's appearances impro\ed."
Both Fletcher and \alle\ plan lo go on
future trips.
'■The mission of RotupUist Inlcinatioii-
al. Inc. is to provide free rt'consinictivc
siiii;cr\for indiiicni children with cleft lip.
cleft palate and other facial deformities.
\ ohintecr doctors and nnr.ses are matched
with Rotary volunteers in host countries,
who take care of paperwork, find patients,
anil provide operaiin:.^ rooms and housin<^
for the team.
Fixing hearts in Nicaragua
You'd never know from the beautiful
Pacific coast that Nicaragua has been
through tw o wars in 20 years. But it has. and
those w ars have taken a toll on the country's
infrastructure.
Since 1986. a group of North Carolina
surgeons have sought to help remedy that
by traveling to the country on medical
missions. They've done so through
"Nicaragua: A Project Leon." a program
started by John Paar. Ml), a Raleigh
cardiologist.
William Sulli\';in. MD. a general
surgeon at Wake Medical Center. AHEC
appointee, and team member, presented his
most recent trip to Leon. Nicaragua during
Surgery Grand Rounds last fall. "Our trips
are a little different from some in that we go
primarily as collaborators." said Sullivan.
".Nicaragua has no lack of doctors. What
they lack are resources. So we go to assist
and exchange ideas."
Built in U)79. Leon's public hospital
has 2.^0 beds, including an eight-bed ICLI.
Despite its si/e. the hospital can care tor a
relatively small number of patients because
ot limited supplies. "There's a lack of nurs-
ing help, equipment, drugs, and things such
as sutures and gauze." Sullivan saiil. "lis
humbling lo realize how much we have and
lake for granted here in the U.S."
In recent years. Sullivan and his leani
have shipped surgical books, anesihelic
machines, lelal momlors. surgical cauleries.
pulse oximeters and surgical instruments to
the hospital in Leon.
When asked whv he uoes on these
trips. Sullivan said. ">'our slicccss as a
surgeon depends on the number ot patients
who leave the hospital better than w hen
they came. To help the people of Leon and
see their improvemeni is an honor. "
Repairing urology problems in
Belize
In Januarv 1999. a pediatrician from
Goldsboro called Tim Bukovv ski. MD.
medical director for L'NC's pediatric urolo-
gy service. "1 have a child w ith a urethral
obstruction that I'd like vou to see." saiil the
doctor. "The onlv problem is ihal he is in
Belize."
Bukovv ski agreed to evaluate the chikl.
He decided that rather than have the child
come to the L'nited States, it would be easier
on everyone if he w ent there. He w as soon
contacted b\ Egbert Grinage. MD. a pedia-
trician in Belize and tounder ot Friends of
Pediatrics, a grass roots organization that
brings specialists to Belize through the sup-
port of the Belize Citv Rotary Club and
local companies.
Bukowski went on his lirsi trip last
.April. He spent three days ihcie. during
w hich time he saw 40 patients and operated
on 10. When he went again in September,
he saw SO patients aiul operated on 12.
using main of the cases lo leach ihe local
dtKlors.
Tmiliukowski.MD
The Belize medical s> stem is state run.
"There are tlve public hospitals and a smat-
tering of private medical practices like in
Britain." said Bukowski. "The problem
there is technology. I can help by bringing
the technology to them."
What did Bukowski take aua\
from the trip? "I guess the biggcsi
thing I tix)k away wa.s ho\\ crucial il is
that the host country need and w am
\our help." Bukow ski said. ""These
types of missions don't v\ork unless
the country has some sort of system to
bring specialists in luid gel patients to
the facilities."
Bukowski said that the real
hero in the story is Dr. Grinage. the
Belizian pediatrician, who has
worked through the years to better
medical care in his country. ""He
really is a remarkable man." said
Bukowski. ""His next goal is to build
a pediatric intensi\e care unit."
experienced life outside the de\eloped
world, and second, il would be a chance for
some great surgical experience."
He traveled with then-UNC fellow Jeff
Wilkerson. MD. a specialist in urogynecol-
ln!/hin\ ( 'uj^plcilLhilili
nicr. KiJLihc. Kenya
Making Indian women healthier
Gil Reid. MD "93. chief resident in
OB/Gyn. spent 1 0 days in Jamkhed. India, a
\ illage 450 miles east of Bombay. It was
there that he w itnessed and participated in a
successful rural health project.
For his third-year residencs project.
Reid had a choice of research or a clinical
experience away from campus. He chose
the latter. "I decided to go that route for two
reasons." said Reid. '"First. I had never
ogy. to the Comprehensixo Rinal Health
Project in Jamkhed. Established by \\\o
Indian physicians trained at John Hopkins
University, the program trains las people in
outlying villages to provide simple medical
care such as vaccinations, prenatal care, and
nmniloring vital signs.
On their first day. Reid and Wilkerson
held clinic for 52 women. "We set up two
exam rooms. There were no beds with
stirrups, so we used regular tables for the
exams." Reid said.
During their 10-da\ stay, they
performed 12 major urogynecological
surgeries, most of them vaginal vault
prolapse repairs. "The degree of prolapse
w as amazing.'" said Reid. ""It's due to poor
nutrition and the high number of
children each woman bears."
Of the rural health project.
Reid said. ""The doctors are able to
pro\ ide medical care that helps the
people physically, but the biggest
impact is social. B\ training women
in the lowest castes to be lay health
workers, they have assured them a
place in their \illages."
Fixing facial deformities in
Africa
This summer. Brian Jewett.
MD. chief ENT resident, traveled to
Kijabe. Kenya with World Medical
Mission.* He was joined by three
other .\merican surgeons, a family
practitioner and an anesthesiologist on the
two-week trip.
For many Kenyans, medical care is
difficult to come by. ""Kenya has a shortage
of medical providers, and most of them con-
centrate their efforts in Nairobi." said Jevi -
eti. "Many people in outlying areas cannot
get to Nairobi for medical care. So when
specialists come to Kijabe. they go there. "
The team spent their time at Bethan\
Crippled Children's Center, a .^6-bed reha-
bilitation center. While there. Jewett and the
others operated on 60 children w ith cleft lip
or palate. They also saw 60 pediatric
patients per day for other ENT problems,
such as thyroid disorders.
""I was impressed by the dedication of
the OR staff." Jewett said. ""Some of our
days were up to 14 hours long, but the staff
were the first ones there and the last ones to
lea\'e. They wanted those children to receive
the care they so desperately needed."
Jewett found that the Children's Center
served not just as a rehabilitation facility but
as a teaching hospital. ""Throughout the
vear. British. Gemian. American and other
specialists come to Kijabe to pro\ ide
ser\ices." said Jewett. ""Doctors training in
Nairobi will visit the center to learn from
the foreign doctors."
*U<))/(/ Medical Mission is an offshoot of
Samaritan's Purse, a Ininianitarian organi-
zation run hy Franklin Graham, .um of Billy
Graham.
Gil Reul. MD. in .Jamkhed. India
International Health Program Receives
$88 Million Federal Contract
An international health program at
UNC recently won S88 million from the
federal government, making it the largest
contract aw arded to the university in its
206-year history.
The tl\ e-\ ear cooperative agreement
K-tween INTRAH and the U.S. Agency for
International Development (USAID) also
IS the largest aw arded to any of the I 6
campuses in the UNC system, said
Dr. Richard W. Linton, associate vice
president for research and director of
sponsored programs at UNC General
.Administration.
The S8S million w ill allow the program
to implement L'S.AlD's new Primar\
Providers Pertomiance lmpro\ement in Re-
productive Health Project (PRIME II).
which is designed to create sustainable,
national s\ stems for training and education
in family planning and reproducti\e health
in developing countries.
PRIME II aims to improve the work
performance of primary health-care
providers in Africa. Asia. Latin America,
the Caribbean, the Near East and the new
mdependent states of eastern Europe and
the former So\ iet Union, said Dn James W.
Lea. director of INTRAH and the UNC
School of Medicine's Office of International
Affairs.
Since its start in 1979. INTRAH and its
worldw ide efforts have followed Carolina's
long-standing tradition of extending its edu-
cational and sen.ice capabilities beyond the
physical boundaries of the campus. Lea
said. He compared INTRAH with the
successful N.C. Area Health Education
Program, which improves the supply, distri-
bution and quality of primary hoallh-carc
pr(>\ iders across the state.
"Our program crosses traditional
departmental lines and allows us to appls
the university's enonnous expertise directiv
upon improving the health of mothers
and infants — a crucial area of concern for
people in North Carolina and arouiHJ the
world." Lea said. "That's what we'll do
even more vigorously, thanks to this
renewed financial support."
With this latest SSS-niillioii coopera-
ti\e agreement. INTR.AH has recei\ed
more than S2()0 million from L'S.AID since
1979. INTRAH has helped local health-
care workers offer men and women
improved access to quality family-planning
services, prevented unw anted or unplanned
pregnancies and campaigned against HIV
and other sexually transmitted diseases.
"We strengthen the performance of
proN'iders as the\ sirise to inipro\e famiK
^ ^ Our program crosses
traditional departmental
lines and allows us to
apply the university's
enormous expertise
directly upon
improving the health of
mothers and infants...
planning and reproductive health services in
their communities." Lea said. "We do our
work through training and other innovative
learning methods, adapting cutting-edge
lechnologN and collaborating closely w ith
host couniiA' colleagues to suppoil national
reproducti\e health goals and priorities."
The PR 1. VIE ifproiect brings together
organizations expericnceil in miernalioiial
health and de\elopment. They incluile Ipas.
a nonprofit reproducti\e health group basetl
m Chapel Hill; .WSC Internalional of New
York; Abt Associates of Cambridge. Mass.;
Training Resources Group Inc.. of .Alexan-
dria. Va.; and the Program tor .Appropriate
Technology in Health in Seattle. The .Amer-
ican College of Nurse Midw i\es and Save
the Children Federation also will work with
the project. INTR.AH has offices in Togo.
India. Kenya and the Dominican Republic.
Building an Academic Medical Center
By Karen Stinneford
While it might surprise someone
navigating around the dump
trucks, cement mixers, pylons
and construction fences that ha\e come
to symbolize "Manning Drive" on South
Campus, the truth is
the UNC School of
Medicine still lacks
sufficient laboratories,
offices and class-
rooms needed to sup-
port, nurture and grow
world-class research,
clinical and teaching
programs. •■■m'
Given the univer- „ tum
sily"s many financial
needs — such as suffi-
cient faculty salarv
money to recruit and
retain the best and
brightest teachers and
researchers and pro-
vide funds to establish
their laboratories — a
"building" can seem
insignificant, at best. That is, until you try to
fiiitl the phvsical space on campus to house
those ne\\ 1_\ hired faculty.
At the most fundamental level, it
is the physical buildings of UNC that per-
mit its faculty, staff and students to fulfill
the university's missions of teaching, ser-
vice and research.
Here's a look at some of the School
of Medicine's cun-ent and planned capital
building projects:
Neuroscience.s Research
Building
This building will replace the fonner
Biological Sciences Research Center,
which was torn down to make room for
the new N.C. Women's Hospital next to
the N.C. Neurosciences Hospital.
"When the BSRC went offline to
make way for the new hospital, the med-
ical school incurred a significant loss of
space," explained David Perry, executive
associate dean for administration. "The
new Neurosciences Research Building
barely gets us back to where we were
before in terms of research space, so we
are greatly looking forward to its coming
online."
The eight-story building will cost
about $30 million, and school officials
Nfiiidscicihcs Rfscanli Ruildiivj.
plan to start moving facultv into the
building sometime this summer. It is
located on Columbia Street, behind the
Thurston-Bowles Building.
The building's "anchor tenant"
will be the UNC Neuroscience
Center, directed by William Snider. MD.
"77. The building also will provide
permanent space for the neurobiology
curriculum, additional space for several
neu faculty members in basic neuro-
science. and faculty "incubator"" space for
the development of clinical neuroscien-
tists with direct research ties to basic
scientists in the center.
Two entire floors of the building vvill
be devoted to laboratory animal inedi-
cine. one of them specifically to house an
Animal Models Center (funded in part by
the Keck Foundation) for UNC"s
"mousers."" researchers who specialize in
the study of mouse genomics. Oliver
Smithies. DPhil. Nobuyo Maeda. PhD.
and Terry Van Dyke. PhD. are just some
of the faculty members steering UNC"s
internationally renowned mouse
genomics program.
Another floor will house the build-
ings administrative and mechanical
tunctions. and school administrators cur-
rently are considering how to best parcel
out the remaining
three floors of
undesignated
research space.
The Medical
Biomolecular
Research
Building
This lOO.OOO-
square-foot. $64-
million facilitv
could house 60 to
80 principal inves-
tigators - presuni-
ing the necessary
funding becomes
axailable to build it.
The building
was approved by
the N.C. General Assembly with the
understanding that the School of Medi-
cine would finance half the cost through
revenue bonds. The uni\ersity is expect-
ed to issue the revenue bonds for the
school's portion of the project sometime
early this year. About S7 million of the
state's share of the project has been
appropriated by the legislature thus far.
allowing the school to break ground and
begin v\orking on utilities and the foun-
dation.
Unfortunately, the N.C. General
Assembly made its agreement with UNC
before Hurricane Floyd devastated eastem
North Carolina.
"We are. for all practical purposes,
out of research space, so this building is
critically important to UNC's ability to
seize opportunities for growth in research
funding by the federal government and
private inclustry."" Perry said. "And we're
in a great position to do so because of the
caliber of our faculty and their demon-
strated ability to gamer our fair share of
those additional resources. Without that
building, however, our ability to do that
is seriously constrained.
"Having said that, though, whii can
say that a research building is more
important than helping the residents
down east rebuild their li\es. their homes
and their li\ elihoods .' .And that's the
dilemma facing the General .Assemble"
Perr\ added.
Plans tor the Medical Biomolecular
Research Building include two auditori-
ums, one that would seat about 300 peo-
ple, the other 300 people. The auditorium
space also is critical. Perry said.
"There realh is no place decent
south ot Manning Drive that you could
call an auditorium." Perry said. "The lack
of an attracti\e multi-media auditorium
has been problematic for people tr\ ing to
arrange lectures by distinguished visiting
scholars and other e\ents we want to
encourage faculty, staff, students and the
public to attend."
If all facets of the funding package
become available on time, the building
could be completed by mid-20()2. Perry
said.
Faculty Office Building
Plans put the Faculty Office Building
on Mason Fann Road next to Odom Village
and behind the medical center's parking
decks comenient to the hospitals and the
Ambulator) Care Center. The fne-story.
S3?-million building would provide facul-
ty, post-doctoral fellows and support staff
with about 61.000 square feet of badly
needed office space.
"The building predominantly would
help our clinical departments by housing
faculty and staff who now. often times,
are housed in cramped, converted
research laboratories and other sites,"
Perry said, adding that the building
would accommodate faculty and staff
currentis working in \arious trailers and
in the antiquated wings B, C. D. F and F
of the medical school.
"Those wings were created nearly .30
years ago to be dorm rooins, not offices,
yet we have them crammed full of
people." Perry said. "The structures aic
mechanically frail, not readily accessible
to the handicapped and located on v\hat
is "prime real estate' for future hospital
expansion, but we can't tear them down
at this time because we have no place
else for people to go. The advent of the
Faculty Office Building will afford the
school the opportunits to better house its
\er\ protluctise faculty and staff, and in
time to demolish the antiquated wings to
make w a\ for future hospital expansion. "
Medical Sciences Research
Building
A wholesale gut rehab and construc-
tive re-use of this 4()-year-old structure
which adjoins MacNider on the north end
is the final component of the School's
major capital program.
""All this vintage building's infrastruc-
ture — heating, cooling, plumbing, electri-
cal systems — is antiquated beyond repair
and in need of complete replacement."
Pern. said.
""While the building's si/e and configura-
tion do not lend themselves to future use
for state-of-the-art biomedical research
purposes, the building can, when fully
ieno\ated and restored, serve the .School
well as teaching and academic support
space. Our current thinking is that the
MSRB. after reno\ation, would serve as
the new home for the School's highly
regarded Department of Allied Health
Sciences, which for some time has been
housed in substandard and insufficient
space in the School's "w ings" buildings."
Other renovations underway include
a floor-by-floor updating of Brinkhous-
BuUitt and the Mary Ellen Jones build-
ings. Burnett-Womack and Berryhill Hall
also need major attention.
""One of the challenges in reiunating
existing buildings is how to complete
construction work at the same time you
need facults to continue to teach and
conduct research m those structures."'
Perrv said.
/•(/( iiln OII'k {■ Hialiliiii;
The Campus Master Plan
Ayers Saint Gross, a Baltimore architectural tlmi specializing
in college campus planning, was hired by UNC"s Board of Trustees
in 1998 to update the master land-use plan tor the 74()-acre
central campus,
A master plan is a blueprint for possible development over
a 20- to 5()-year period. When completed, the plan will guide
decisions about new buildings, renovations, green space, parking,
transit and pedestrians — helping UNC prepare for future growth
while enhancing the beauty for which the campus is so uell know n.
The last master plan tor UNC's central campus v\as completed
in 1991. .Since then, several developments made updating the plan
critical:
• A construction boom. Today, the central ciuiipiis houses more than
l.'^O buildings, plus 29 residence halls. Fourteen capital projects
totaling $50 million were completed between July 1998 and Janu-
ary 1999. and 26 projects valued at $15,^ million now are under
constmction. Another .'iO projects with a S279 million price tag
are in desicn staces.
Completion of the Chancellor's httellectual Chmate Task Force
Report. Along with major recommendations about academic
programs and facilities, the report stressed the importance
of well-designed indoor and outdoor spaces to foster intellectual
conversation.
Enrollment growth. UNC trustees have endorsed a plan to add
3,200 new students by 2008, The endorsement stemmed from a
UNC system call for its campuses to address a sharp increase in
the number of high-school students who wish to attend college in
the next decade.
Shortage of research space. Recent studies commissioned bv the
UNC system and Carolina have documented an extreme academ-
ic space crisis on the Chapel Hill campus, especially for research
laboratories and offices. Administrators say the lack of essential
research, graduate student office and enhanced instructional space
threatens the university's ability to attract and retain highl\ quali-
fied faculty.
Medical Biomoleadar Research BuiUing
Surgery Students Create
Hugh Williamson Society
The neul> tomied Hugh WiUiainson
SoLieiN. a group for medical
students interested in careers in
surgers'. held its first meeting last fall. The
society's mission is to pro\ ide educational
and mentoring opportunities for first- and
second-\ear medical students interested in
surgical practices in academic medical
centers or communit\ -based practices.
The society was named for Hugh
Williamson. MD. in appreciation for his
pioneering contributions to medicine in
North Carolina during the era of the Revo-
lutionary War. In 1780, Williamson was
appointed surgeon general of some 4.()0()
North Carolina militia sent to help defend
South Carolina and Georgia against British
forces.
Williamson studied medicine under
John Hunter, who is known as the "father
of scientific surger> '" and came to America
after practicing on the European continent.
Williamson ser\ed as a go-between
for Benjamin Franklin and the leaders of
the evolving American Revolutionary
Committees of Safety. When the Revolu-
tionary War broke out. he traveled to North
Carolina, where he remained inlimateh
connected with North Carolina troops until
the war's conclusion.
Follow ing the end of his career as an
army surgeon in the field. Williamson
became a distinguished legislator. He was
an active delegate to the Federal Conven-
tion and sened in the first U.S. House of
Representatives. Along with William R.
Davie, the founder of the University of
North Carolina. Williamson helped choose
the location of the university in Chapel
Hill: he also served as one of its first
trustees and donated money for the first
library.
The Hugh Williamson Society's first
speaker was Christopher Baker. MD.
professor of surgery. Baker shared his
insight on surgical careers based on
information he has gathered during his 20
years as ;ui academic surgeon.
David Cierber. MD. and David Ollila.
MD. will serve as the society's faculty
advisers. Students Ian Buchanan and John
Meisinger will serve as co-presidents.
./V^--'y
n„m^fi>-
^
i
¥ ^
4..
<^U<
¥'
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y
//'
Besides offering students educational
ami mentoring opportunities, the societs
will select one student annually to receixe
the Hugh Williamson. MD. Award for
Excellence in Surgcrs. in be presentetl
to the outstanding siiulcnl on surgical
rotations at commencement. The winner
will attend the annual Clinical Congress of
the .American Ci
supjiorl from llu
and the ACS.
liege of Surgeons
department of su
with
rgery
Cuban Pediatrics Patient Take
By Lynn Woolen
All the conditions were present to
produce a major media stomi: Cuban
President Fidel Castro, his political
toe. U.S. Sen. Jesse Helms; the United
States' controversial embargo that prevents
medical supplies from entering the country
and a theologically liberal congregation ot
N.C. Baptists.
At the eye of the media storm stood a
7-year-old Cuban boy about whom some
Ainericans claimed — and Cuban officials
denied — would die from a congenital liver
ailment if he didn't get proper medical treat-
ment in the United States.
The church involved. Pullen Memorial
Baptist in Raleigh, learned about the plight of
young Raudel Alfonso of Matanzas, Cuba,
when one of its members, the Rev. Ned
Walsh, a retired Baptist chaplain, visited the
country scouting for Habitat for Humanity
building sites. A doctor there told Walsh that
Raudel needed medical treatment in the Unit-
ed States because doctors couldn't properly
treat him in Cuba.
Moved, Walsh was even more touched
when he learned that Raudel 's mother and
father had lost two other children to the same
liver ailment Raudel siilTeied. When Walsh
returned to North Carolina, he enlisted his
congregation to lobby the Cuban and Ameri-
can governments to allow Raudel and his
mother to make an emergency trip to the
United States.
To expedite the process. Walsh asked
North Carolina's senior U.S. Senator. Jesse
Helms, to intercede on the child'.s behalf.
Helms, a longtime opponent of Fidel Castro
and a staunch supporter of the U.S. embargo
of Cuba, contacted U.S. Secretary of State
Madeline Albright seeking an emergency hu-
manitarian visa for Raudel and his mother,
klalmis Alfonso G;u-cia.
Ill the meantime, organizers of Raudel's
visit approached LINC Hospitals and asked
officials to treat Raudel. The hospital agreed.
After Cuba showed little sign of letting
mother and son leave. Illinois Gov. George
Rvan. who was in the country on official
business, heard of the problem and stepped
in. Ryan negotiated the pair's release and
accompanied them to Chicago before send-
ing them on to North Carolina.
Raudel and his mother arrived at
Raleigh-Durham International Airport Oct.
2^) and were taken directly to LINC Hospitals.
Having experienced a media maelstrom in
Chicago, the two braced themselves for
reporters and photographers awaiting them at
the airport and hospital, where they briefly
posed for photographs. Media including
^ • After the veins are
clotted oif — through
a procedure called
sclerotherapy that UNC
pediatric gastroenterologists
have done for more than 1 5
years — we believe Raudel
can return to Cuba with
this problem behind him
at last, Rhoads said.
CNN. ABC News, USA Today, the Associat-
ed Press, The Chicago Tribune. The News
and Observer of Raleigh. The Hcraid-Siin of
Durham and local TV stations followed
Raudel's Journey.
A L'NC pediatric and surgical team led
by Marc Rhoads. MD. professor of pediatric
gastroenterology, found that Raudel suffered
from portal vein thrombosis w ith extensive
collateral circulation. This meant Raudel had
several small high-pressure veins leading
into his liver instead of one "high-tlow" vein.
and as a result, blood backed up into his
esophagus. The condition often occurs as a
result of an innammation of the umbilical
vein during the perinatal period — a medical
treatment the youngster had received as a
newborn.
A lengthy diagnostic prcKCss to help deter-
mine the best course of treatment ensued.
"He got a really good looking over by
many of us." said Rhoads. "All during his first
week here. UNC doctors contemplated if
surgery could be done to "bypass' his clotted
portal vein and decompress his large
esophageal varices — the veins which bled
w hen he was in Cuba."
"During an angiography, we learned that
Raudel had de\ eloped a spontaneous shunt.
Thus, he already had a large, naturally devel-
oped left spleno-renal shunt, as well as exten-
sive collateral veins going into the liver,
which made the surgical creation of a spleras-
renal shunt unnecessary."
UNC physicians determined that the
best course of treatment was a series of
sequential procedures rather than full-blown
surgery. The relatively minor treatment,
called endoscopy sclerotherapy, involves
endoscopy and injecting Raudel's four large
veins in the low er esophagus to clot them.
"After the veins are clotted oft^ through
a procedure called sclerotherapy that UNC
pediatric gastroenterologists have done for
more than 15 years — we belie\e Raudel can
return to Cuba with this problem behind him
at last." Rhoads said. "There will be a small
chance of re-bleeding, but the risk of massive
hemorrhage w ill be very low."
Raudel underwent his first procedure
Nov. 8. stayed overnight and was discharged.
He and his mother stayed w ith members
from Pullen Memorial Baptist before return-
ing to UNC Hospitals two weeks later for
foUow -up esophageal sclerotherapy. In early
December. Raudel and his mother returned to
Cuba, where he might have to undergo the
procedure one or two more times, Rhoads
said.
"But he's looking fine." Rhoads said.
"He's not having any symptoms at all. And
he's now at lower risk of bleeding again."
10
itemational Adventure To UNC
Kiiiulcl MIdiisn and his nwrhfr urnviii'^ <// I \( ' llmpiuil},
At 97, He Stares at Scars
So Others May Breathe
By Joel B. Obermayer
Rcprinti'J with pcnnisston fruni the News
ctC)/).vc/V(7- of Raleigh
Hcifihin liii.soiN. ML)
On a recent weekday morning.
Dr. Hemian Easom was in his office holding
an X-ray of a man's chest. Leaning forward,
he traced the faint outline of the bronchial
passages. No scarring. He threw the film in a
stack and pulled out the next one.
At age 97. he's been interpreting X-rays
for the public health department for more
than 60 years. He has no intention of stop-
ping alls time soon.
"I can't imagme not doing it." Easom
said.
Indeed, he still does it tw ice a month.
2(X) X-rays at a time, making him the longest
continuously serving public health employee
the state has e\ er had.
Easom 's career is legendary in the state
public health department. He started the
state's department of occupational health in
the 1 93()s w hen he and an engineer drove
around North Carolina in a pickup truck.
Back then. the\' towed an X-ray machine so
the\ could check workers' lungs for damage
caused b\ industrial pollutants.
"He was a pioneer. Before Dr. Easom.
there really wasn't much state involvement
in (workers'! health." said Debbie Crane,
state public health department spokes-
woman. "And then, there's his endurance...
He just loves w hat he does."
Easom. a Selma native, was a pre-med
student at the University of North Carolina at
Chapel Hill. In the 1920s. UNC had a two-
year graduate medical program. To finish his
medical degree. Easom had to travel to
.St. Louis. After that, he w orked a summer tor
a state tuberculosis sanitarium. In 1935. he
landed a job with the state public health
department.
Back then. plent\ of factories worked
w ith asbestos. It was particularly popular to
w ea\ e it into cloth for industrial uses.
Also, rock quiuries and other companies
that cut or crushed rock produced tine dust
panicles that workers routinely breathed in.
Few workers were aware of the health
problems that could result.
Easom began to address that by setting
up the North Carolina Dusty Trades Pro-
gram. It was the first time the state had
become actively invohed in an occupational
health issue.
Easom and an engineer set out to visit
nearly every employer in the state w ho
worked w ith asbestos or finely ground rock.
Later on. the two men did another set of long
road trips taking X-rays of workers' chests.
What they found was a public health
menace. One of the places they visited was a
mine in the Sandhills where workers were
packing talc powder the consistency of fine
flour: it was used as an additive in paint and
for batteries. Looking at the X-rays. Easom
found that one-third of all v\orkers there,
young and old. had lung damage from the
dust.
"We were shocked. We had no idea the
problem was that serious." Easom said. "The
workers didn't know they were getting sick."
One exception was a man Easom met
who could hardl\ breathe. The man was in
his late 20s and had been bagging talc in the
factory for less than 10 years. He eventually
died because of the damage to his lungs, and
Easom and a pathologist exhumed the bod>
to prove that the man's death was caused by
the dust.
That v\ as turning point. Easom said.
He w as able to use the autopsy to show
the company and the workers v\ hat was
happening. TTie company abandoned the plant
and replaced it w ith one that had much better
dust control. Easom persuaded many other
emplo\ ers to ch;inge their practices. a.s well.
Easom. v\. orking with members of the
U.S. Public Health Service, published a pair
of research papers about w hat he had found
w ith his X-rays. The papers eventually
became the basis of national health policies
I ol lowed by the Centers for Disease Control
and Prevention and the National Institutes of
Health.
Pat Curan. an industrial hygiene
engineer in the state Department of Health
and Human Services, said he has know n
Easom for 28 years but has rarely heard him
talk about this accomplishment.
"His papers were the backbone of nation-
al health policy, but he doesn't talk about it
except in tidbits. He's too modest." Curran
said. "I had to hear about it from the folks at
CDC and the National Cancer Institute."
Easom eventually decided he wanted to
see patients regularly. In 19-14. he took a job
as director of a state sanitarium for tubercu-
losis patients in Wilson. He often read .\-rays
there looking for lung damage.
But his hospital was as much as ware-
house as a treatment facility. For TB. thefe
were no effective drugs. Patients were pre-
scribed rest and. occasionally surgery, but the
disease often w on. Of ."iOO patients at the
sanitarium, about 40 a year died. Easom
would return to Raleigh on weekends to read
chest X-rays for the Dusty Trades Program.
Again. Ea.som w as at a historical tuming
point.
In the 1930s, antibiotics were intro-
duced that could attack tuberculosis.
"It was a huge change. The drugs made
all the difference in the world." Ea.som said.
"People who would have surely died, got up
and w alked out of the hospital."
By 19,5.5. the sanitarium was no longer
needed and w as converted to a mental hospi-
tal. But Easom continued to work on TB issues,
mnning seminars and clinics for county health
departments. He retired in 1 975.
Of course, that couldn't keep him from
coming to Raleigh to read his X-rays.
Over the years, a stroke and cataract
surgerv haven't stopped him. He has slowed
diiwn a bit, and he doesn't walk as well as he
did. but his evesight is still good enough to
look at films. While he drives his Cadillac
iiround Wilson, he now gets a ride for the trip
totheTriiuigle.
"I've just been incredibly lucky."
Easom said. 'T'\e done more than I ever
thought I'd do."
Alumni
Notes
30s
Kutus R. Little. AB '28. MI) '30. believes
he nia\ be the only li\in2 alumnus of the
class of 1930. He asks if there are an\ other
sur\ i\ ing "28 or "30 alumni that lhe\ notify
the editor of the Medical Alumni Bulletin.
Little, now 92. remains active. He and his
u ife have three erow n children.
40s
Carlton G. Watkins, MD, FAAP '40, has
\\ ritten Bcyciul Medicine: A Ccnliiry of
Parcntiiii; and Pediatrics in Charlotte and
Mecklenhiin^ Counties (190.^-1999). The
book contains the biographies of 250 pedia-
tricians, other physicians, dentists and other
allied health personnel. It also records the
history of government agencies and ci\ il
and social organizations involved in child
welfare. The book is available from Broad-
foot Publishing Company.
John B. (Jraham. MD '42, has published
his founh book since retiring in 19S.5. It is a
cixikhook titled Southeastern Cookiiii^.
60s
C\ (iray. .MI) "66, plans to retire from his
gynecology practice this winter. Gra\
says that his health is still good, and he
looks forward to retirement. He was also
recently elected president of the Southern
Gyn/OB Societv.
Howard D. Honusley, MI) '67, has
returned to \ash\ ille. Tennessee, to join
a group practice after 24 \ears in .North
Carolina.
70s
National Board of Medical Examiners in
March. Her responsibilities include organi-
zational consulting for academic and other
healthcare organizations. Her specialties
include strategs consultations, leadership
development and executive coaching. Her
email address is CAschenbre(2)aol.com.
80s
Anna Bainbridge, MS '82. has been
promoted to Director of Practice at the
.American Ph\ sical Therapy Association
located in Alexiuidria. Virginia.
Lisa Koehler Burke, MD '89, is an emer-
gency medicine physician with Peachtiee
Emergency Asstxiates at Piedmont Hospital
in Atlanta. She and her husband. .And\ .
recently celebrated the birth of their son.
Adam Marshall.
90s
Carol A. Aschcnbrener, MI) '71. began
her first two-year term as chair of the
Lnri \\. Balaban. MD '90, her husband.
Da\ id. and stin. Michael (age 3 1/2). recently
welcomed Joseph Daniel into their fannly.
Balaban is a pediatrician in pri\ate practice.
Lawrence R. Nycum. MI) '90. recently
completed a fellow ship in g\ necological
oncology at Walter Reed Armv Medical
Center and the National Cancer Institute.
He is now Division Director of Gynecologic
Oncology at Da\ id Grant Medical Center,
located on Travis .Air Force Base in Califor-
nia. He holds the rank of major. Nycum also
recentl\ was aw;irded "'Best Scientific Paper
on Oncology"" bs the American College of
Obstetrics Anned Forces District Meeting.
He can be reached at Inycumrn aol.com.
Billie ( osj-rove. MI) '92, and Chris
( osgnive. MI) '92, are happs to he back in
■North Carolina. The\ ha\e two chiklren.
Spencer. .5. and Elly. 2.
Cuiien Rutr. MI) '92. completed a fellow-
ship in abdominal imaging at Georgetow n
Universitv in June. He has joined Fairfax
Radiological Consultants in Fairfax. V.A.
Ruric (.\ndy) .Anderson. MD "93. is an
assist;uit professor of medicine ;uid associate
program director for the Internal Medicine
Residency at the Medical College of
Wisconsin in Milvvaukee. He and his wife.
Holly, are expecting their first child in .April.
He can be reachetl at runcC« mcw.edu.
Laura B. Knyedi. MD '93. joined the Duke
Eye Center facultv as an assistant clinical
professor of ophthalmologv this August.
Her specialty is pediatric ophthalmology
and strabismus. She works part-time, as she
is also the mother of 3-year-old Emily and
14-month-old .Andrew. Her email address is
en\ed(K)l(a mc.duke.edu.
John Phipps, MI) '93, joined Forsyth Inter-
nal Medicine m Jul\ 1998. His specialty is
endocrinology. He ;ind his w ife. Melissa. ;ire
expecting their third child in Febm;iry .
Allison Poston, MD '95, completed her
pediatrics residenc\' at the L ni\ersiiy
of Kentucky in Lexington and has joined
Pediatric and Adolescent .Associates, a
pri\ ate practice.
William L Smith IN. Ml) '96. has com-
pleteil his internal metlicine resuleniA. He is
now a cardiology fellow at Duke L'niversity
Medical Center. He and his w ife recently
celebrated the birth of their son. Willuim
"Thomas" Smith \'.
Harriet N. I)a\ is. Ml) '99, has joined
Ghent lamiK Practice Residency Program
in Norfolk. Virginia. She can be reached at
tiaMshnfa fammetl.e\nis.etiu.
13
UNC Study Points to
Chromosome Site of Autism Gene
By Leslie F. Lang
UNC researchers and collaborating
institutions are reporting evidence
for a possible gene on chromosome
13 that causes autism.
The group's report was published
Dec. \5 in the Amciican Juunud of Mcdkol
(ic'lhiics.
Autism is a severe neuro-developmen-
tal disorder marked by social and comniuni-
cation deficits and ritualistic-repetitive
behaviors that are detectable in e;irly child-
hood luid continue throughout life.
"For a long time autism was not
\ievved as being a genetic disorder." said
loseph Pisen. MD. professor of psychiatr\
and new director of the university's Mental
Ketartlation and Developmental Disabili-
ties Research Center. "It has a high degree
of heritability, confirmed by twin studies
that show a substantially higher rate in
identical twins - so much so that heritabilits
is more than 90 percent."
According to Piven, a child psychia
trist. families with an autistic child nin up
to a 5 percent risk of having a second child
with autism.
"And while that percentage is not so
high, it's substantially higher than the rate
of autism in the general population. v\ hich
is approximately five in lO.OOO kids" he
said. "The data is pretty overwhelming that
autism is strongly genetic, more so than
schizophrenia or diabetes."
Still, despite epidemiology evidence
of a strong genetic influence. Piven and his
collaborators note that the search for
autism genes only recently has begun in
earnest. TTie new study is one of a handful
v\orldwide to genetically screen the DNA
of nuclear families of autistic siblings.
Tliis imestigation inwlved 7."^ families
w ith at lea.st two autistic children, including
three families having three autistic children.
The children's ages ranged from 3 to 31
years old.
Findings v\ere based on an assessment
of participants' DNA prepared from blood
samples. The researchers spaced 416
nucleotide markers on selected chromo-
some regions for each individual. The
markers helped identify those regions
across individuals containing similar
clusters of nucleotide sequences. .Statistical
analysis then determined if the presence of
these regions was significantly greater than
chance. For a region of chromosome 13.
the answer was yes.
The study also highlighted several
other possible DNA hot spots for autism
genes, notably a region on chromosome 7.
This latter finding confimis a 1999 report
by an international autism research team.
The new evidence akso converizes vs ith
According to Piven. a child
psychiatrist, famihes with
an autistic child run up to a
5 percent risk of having a
second child with autism.
that from another research group for a
location in the same region of chromosome
7 that is cunently implicated in some form
of specific speech and language impair-
ment, a disorder having characteristics that
overlap that of autism.
"We believe there must be more than
one gene involved in autism." Piven said.
"As in all complex behavioral disorders,
there's no clear evidence when looking
at family pedigrees or family trees that
suggests a single-gene may underlie this
disorder."
In the second stage of the project,
also funded by the National Institutes of
Health, the research group will add 100
new lamilies for a follow-up analysis.
Participating institutions include New
England Medical Center/Tufts University
School of Medicine. Vanderbilt University
School of Medicine. University of Iowa
College of Medicine, the Johns Hopkins
University School of Medicine and
Harvard Universitv School of Public
Health.
Besides the genetics of autism. Piven
also uses neuroimaging (with magnetic
resonance imaging) to study structural
differences in the brain of autistic
individuals. He was the first researcher to
report that brain size is greater in autistic
persons, an enlargement that may be due
to certain timing during the process of
neuronal development.
With new funding from the National
Institute of Mental Health. Pixen's center is
conducting a longitudinal stud) ol children
ages IS to 3.*^ months old with autism or
probable autism.
""Basically, we want to look at the size
and shape of the brain to gain insights into
this observation of enlargement, that it may
encompass some developmental abnonnal-
ities in the brain during early postnatal
development." he said.
14
Faculty
Notes
Damon Anagnos. MD. has been
selected to participate in the 1999-2(101
Teaching Scholars Program, a program
designed to recognize and promote teaching
as a critical scholarh function.
(hristopher (". Baker. MI); Ki'\ in
Ikhrns. Ml): Cerald Sloan. Ml):
Anthonv A. Mexer. Ml). PhD: Amelia
Drake. Ml): and Timothy Bukowski. MI).
were among the t'acult) to recciN e School of
Medicine Roster of Teaching Excellence
a\s:u"ds.
Margaret E. Bentley. PhD, has
been named associate chair of the Depart-
ment of Nutrition. She will be responsible
for o\ ersight of academic programs in the
department.
Culley Carson, MD, has been named
president ot the Urological Research Soci-
ety. His lenii expires September 21KKI.
Elizabeth Crais, PhD. associate pro-
fessor of speech
and hearing
sciences, was
recently named
,1 tellow in the
Amcncan
Speech-Lan-
uiiage-Hearing
.Association.
Crais was
recognized for
preparing grad-
uate students
and practition-
ers to pro\ ide famil) -centered assessment
and interxention ser\ ices.
Thomas E. Curtis. MI), professor of
psychiatry, v^as recognizeil as the I'M)'*
Distinguished Alumnus at the annual
George Ham Symposium.
Matthew Ewend. Ml), his been
selected to participate in the I ';9';-2()()l
Teaching Scholars Program. He also
received a ClinicalAIranslational Research
Avsard from the UNC Linebeiger Compre-
hensive Cancer Center.
Cicii.s
Carol A. Eord, MD, assistant profe
sor of pediatrics
and medicine.
recei\ ed a four-
> ear. S240.00()
Generalist
Physician Fac-
ult\ Scholar
Program .Aw ard
from the Robert
Wood Johnson
Foundation. ^ -
Ford will use ^^
the money to [oiil
support her
research of adolescent behavior.
Joyce Harp. MD. assistant professor
of nutrition, received the James Woods
Junior Faculty .Award from the L'NC School
of .Medicine. This aw ard recognizes one out-
standing junior facultx member for contri-
butions to clinic.il leaching and research.
Karen K.
Holfman. RN.
MS. CIC. clin-
ical instructor
of infectious
diseases and
associate direc-
tor of the State-
wide Program
for Infection
Control and
Epidemiology,
was recent 1\
honored by the national trade magazine.
Iiifci nun Ccnii'dl laihix. as educator of the
\ear.
Jack Eongenecker. PhD. clinical pro-
lessor of nutniion. was selecleil as a fellow
ol the American Social Nutrition
Sciences.
.Mice I). Ma. .MI), assisianl prolessor
of meilicine. was awariled a Junior Faculty
Scholar Award at the 41st annual American
Society of Hematology (ASH) meeting held
last December. The two-vear award
HoJJnicin
pro\ ides funding to scientists who ha\e
recentl) begun their rese;irch ciu'eers ;uid lU'e
studying blood, blood diseases, or blood-
forming tissues. Ma is one of se\ en scien-
tists to receive a 1999 award.
Michael
Mill. Ml), in
tenin di\ ision
chief of cardio-
thonicic
surgery, was
named a mem-
ber of the Uni-
versity Health
Consortium's
CPAC Heart
Transplant
Clinician Coor- Mill
ilinating Committee and CP.AC Heart Trans-
plant Clinical Benchmarking Liaisons.
Kim I'rich. MS\N. clinical instructor
and case manager for the UNC Cnuiiofacial
Center, has been appointed to serve on the
National Advisory Dental and Craniofacial
Research Council of the National Institutes
of Health.
Research
Briefs
Study confirms protein
culprit in alcohol-induced
liver disease
For ihc first linie. UNC scientists have
used gene-knoci\out technology to identity a
i^ey molecular player in alcohol-induced
liver disease.
A report on the study appeared ni the
journal Gastroenterology. The findings
carry implications for targeting new treat-
ments aimed at preventing alcohol-induced
hepatitis and cirrhosis,
"Having this knock-out technology will
help us develop drug therapies lor this
devastating disease, which affects 1 1 million
people in the United States alone."" said
senior study author Ronald G. Thurman.
PhD. professor of phamiacology.
The report pointed to tumor necrosis
factor-alpha (TNF-alpha) as the liver injury
culprit. This hormone-like protein is pro-
duced in the liver and cells throughout the
body. An immune system cytokine, it is a
central pro-intlammatory molecule.
The study offers the first solid proof
that TNF-alpha figures importantly in the
development of early liver injury as.sociated
with long-tenii alcohol consumption. Previ-
ously, higher levels of TNF-alpha were
founil in alcoholics with hepatitis and labo-
ralon. studies ha\e shown that luitibodies to
TNF-alpha attenuated alcohol-induced liver
in|ur\. But the cytokine"s role in the disea.se
remained unclear.
/■('/■ more information, see http:ll
www.iiiH.cduhwwslnewsscn'limivlliYerlOQ
4W.htm.
UNC researchers look at
effectiveness of new cancer
drug
A clinical study at UNC is testing
the effectiveness of a new drug for treating
cancers of the ovaries and endometrium, the
lining of the uterus.
Tlie clinical trial, sponsored by Eli Lilh
and Co. of Indianapolis, is the only one in
North Carolina to test this latest selective
estrogen receptor modulator ( SERM ».
known by its investigational number
LY.\';.\"^81,
Unlike traditional chemotherapy, side
effects associated with the drug are minimal.
Moreover, the drug is given orally, rather
than administered through intravenous
infusion.
"Traditional chemotherapy is usually
cytoto.xic — it kills cells. And when it kills
cancer cells, it kills some of your healthy
cells,"" said Linda Van Le. associate profes-
sor of obstetrics and gynecology. "And side
effects associated with traditional
chemotherapy can include hair loss and
decrease in white blood cell count. When
white cell count is decreased, a major
concern is an increa.sed risk of infection.""
According to Van Le. LY353381 does
not have these side effects. However, there
may be hot flashes and an increased risk of
deep venous thrombosis, fomiation of blood
clots in veins.
For more information, see htip::!
\v\v\v.unc.cdiilnewslnewsseiyliinivlserm2IO
OlW.lwn.
New biomarker could
improve screening for
cervical cancer
Researchers at UNC are studying
the value of a new biomarker for improving
cenical cancer screening.
The clinical trial will examine cenical
smears for lelonierase. a protein released
into cells when chromosomes shorten, stick
together and become genetically unstable.
TTie protein helps rebuild eroded telomeres,
the caps at the ends of chromosomes. Its
presence in cervical cells removed during
Pap smear testing may help predict which
women are at greatest risk for developing
cancer.
"Pap sme;ir screening has been very ef-
fective at decreasing the number of deaths
from cervical c;incer. but many of the abnor-
mal results it produces do not lead to an
increased risk of cancer."" said John
Boggess. MD. assistant professor of obstet-
rics and gynecology. ""A lot of women
undergo expensive testing and painful
procedures only to find out they've got
something that doesn't need treatment or is
unlikel\ to become cancer.""
According to Boggess. a gynecologic
oncologist. Pap smear sensitivity is only 70
percent and can be as low as 50 percent in
women w ith ulceration and innammation of
the cer\ ix. conditions commonly found in
women with cancer. More than 2.5 niillion
abnormal Pap smears are reported in the
United States each year.
For more information, see httpill
www. line. echi/new.s/new.s.'ieiT/univ/cen'i
callllOI'-N.htm.
New molecular clues may
help control herpes
A UNC study may have identified a
new way to halt herpes simplex \ irus in its
molecular tracks.
The findings — though still too basic
lor clinical use — shed new light on how
this stubbornly, persistent virus reproduces
itself within nerve cells and may suggest
possible ideas for designing therapies aimed
at specific molecular targets.
"The picture that"s emerging is that the
virus, because it"s an intracellular parasite,
subverts nomial regulatory cellular mecha-
nisms in ways that optimize its own replica-
tion."" said Steven L. Bachenheimer. PhD.
professor of micrt)biology and immunology.
Reporting in October"s .loiirnal of
\irolog\. Bachenheimer and Tim L
McLean, a student of genetics and microbi-
ology, noted that a cellular protein kinase
called JNK. (pronounced "junk"") seems
important for herpes simplex virus type- 1
(HSV I) to replicate. HSVl is the highly
transmissible herpes virus associated with
painful cold sores.
"If we inhibit the activity of JNK. we
see a reduction in viral yield in the cell,""
Bachenheimer said. In some cells, the
reduction was significant, he said. Viral
replication w as down about 70 percent.
F(ir more information, see http:ll
www.Hnv.edulnewslnewssenUmivDicpeslOl
399.htm.
16
Protein in Epstein-Barr
virus causes B cell
lymphoma in mice
UNC scientists, wcirking u ith Loiieagues
in Japan, have proven that a protein called
latent membrane protein I in Epstein-Barr
\ inis causes a fomi of c;incer known ;i.s B cell
hinphomainmice.
The work is important, the scientists
say. because it shows the protein's central
role in Epstein-Barr \ irus" ability to change
normal cells into cancerous ones. TTiat \ irus
already is known to cause infectious
mononucleosis in humans and has been
associated w ith such malignancies as Bur-
kett's lymphoma. Hodgkin's lymphoma and
ncse and throat cancer. It is especially haz-
ardous to AIDS patients and other patients
w hose immune systems ha\ e w e;ikened.
""We have show n for the first time that
Epstein-Barr virus clearly can cause
cancer."" said Nancy Raab-Traub. PhD. pro-
fessor of microbiology. ""Now we can go
after the specific protein that is responsible
and perhaps one day stop that protein func-
tion and pre\ ent the cancer from grov\ ing."
The first report on the continuing
research appeared in the Proceedings of the
National Academy of Sciences last year, and
a second describing additional findings in an
October 1W9 issue of the journal Science.
For mure information, see http:ll
wM'w.itnc.edulnewslnewssenlreseanhlraah
ilODVW.htm.
Gene mutation tied to
deafness in blacks, whites
A new UNC study is the first to
establish that a gene mutation associated
w ilh about 20 percent of all cases of hercdi-
lar\ deafness found in white people is also
tiiutul in blacks.
"There have been some reports m the
scieniillc literature on Caucasians, but onK
a small stud\ on African-Americans, anil
they didn't find the mutation." said Eliza-
beth .VI. Rohlfs. PhD. clinical assistant
prolessor of pathology and laboratory
medicine.
Rohlfs and colleagues tested DNA
samples of 50() w hites and 5(X) blacks for the
mutation knov\n as 35-delete-G (35delG).
Healthy carriers of the mutation carry only
one cop\ from either their mother or father.
When each parent has a copy, one in four
offspring risks inheriting a pair and is bom
deaf. These are the odds for inheriting a
recessive genetic trait.
""We found a two percent carrier
frequency of .\'^-delete-G in Caucasi;uis and
a 0.4 percent carrier frequency in African-
.Americans."" Rohlfs said.
In North Carolina's general population,
this ratio translates to a frequency of one in
10.000 for whites and 1 in 2.^0.000 for
blacks. The findings were reported at the
annual meeting of the American Societ\ of
Human Genetics in San Francisco.
For more inforniation. see Imp://
iiiru./(/i( .('(//( news neusserv/univ/diieneK)
iwyjimi.
Gamma tocopherol
may boost risK of knee
osteoarthritis
A component of vitamin E. known
as gamma tocopherol, may somehow
contribute to arthritis, a unique new study of
\ ilamin E and the painful degenerative
illness suggests.
The study, described at a recent
American College of Rheumatology news
conference in Boston, also suggests that bas-
ing a high proportion of alpha tocopherol -
the most common ingredient in \ itamin E -
relative to gamma tocopherol ma\ help
prevent arthritis, at least in knees
Joanne Jordan, MD, research associate
professor of medicine, presented the finil-
ings. A member of the Thurston Arthritis
Research Center. Jordan is principal iinesti-
gatorof the Johnston Counts Osteoarthritis
Project, a large, gosernment-sponsorcd
studs of the illness that lor Ihc lirsi nmc
incluiles m;uis black subjects.
/•(</■ more informcilion . sec Imp."
www. line Clin iie\vs:i)ew\serv research jodu
nlll7W_lirm.
17
Alumni Profile
This Doctor is No Stranger to Writing
By Melissa Matson
Frank Huyler. MD. MPH "93. enjoys
observing the world around him.
That characteristic has served him
well in his career as an emergency room
physician. It has also served him well in his
avocation; writing poetry and prose.
Following up on a suggestion to write
about his ER experiences. Huyler recently
hit the road on a book tour promoting The
Blood ofSlnmi;crs: Sloric.s from hjii('ri;cncy
Medicine. In his book, he sought to recount
interactions with patients in ways that
would challenge his readers.
"There's a lot of hype surrounding
emergency medicine." said Huyler. "And I
saw this book as an opportunity to offer an
honest look at an often misrepresented
world."
In one story, for instance. Huyler
describes caring for the victim of a gunshot
wound. .After rirshing his patient to surgeiy
and spending the night w ith him in the ICLI.
Huyler learned that the man \*.as a murderer
He w rites:
When I came lo sec him. before sunrise. I
found a police officer silting in a chair
reading a magazine. The policeman
yawned when he saw me. put down his
magazine, and came out lo talk. "He's a
had one," he said, gesturing to the mon-
strously distorted figure. "We think he
killed at least two convenience store clerks
last year." "Really .'" The cop nodded.
"Killed them both, after he'd got the
money... Right through the head. We've
been after him for a \ ear."
The child of two itttemational school-
teachers. Huyler grew up overseas, in the
United Kingdom. Japan. Brazil and Iran.
"Growing up overseas, being a foreigner,
encouraged me to sit back and look at the
bigger picture." said Hu> ler. "It helped me
as a writer."
In his late teens. Huyler decided to go
to Williams College, a liberal ails college in
Massachu.setts. where he earned a Bachelor
of Arts in English. It was during that period
in his life that he began to v\ rite seriously.
"Williams College was very fertile ground
for me in that respect." said Huyler. "I had
access to some ver\ prominent writers v\ ho
ga\e me \aluable ad\ice and encourage-
ment. I've continued to w rite ever since."
Frank Huyler. MD. MPH. V.^
Despite his obvious affinity for writing,
he decided to pursue a career in medicine. "I
wanted a sense that the daily v\ork I did v\as
important and that it had a tangible and real
impact on people's lives." he explained. "I
never considered the possibility of being
able to support myself through writing. "
With that motivation, he applied to and
was accepted by LINC's School of Medicine.
"I was really fortunate in going to UNC."
said Huyler. "I was under the false impres-
sion before school started that I'd have to
put my interest in the humanities on hold.
But v\hat I found is that L'NC emphasizes
the humanities in addition to the practical
side of medicine."
Among his mentors at UNC were Judith
Tintinalli. MD. MS. chair of Emergency
Medicine, and Jim Manning. MD. associate
professor of emergency medicine, who
.served as his career goal advisor. "TTiey went
out of their way to be supportive." said
Huyler. "And they encouraged me to
consider emergency medicine for my career."
After graduation. Huyler w ent to Albu-
querque. New Mexico, for his residency.
While there, he started on his first book.
"My department chair. Dr. Da\id Sklar.
liked to write, and he knew that I did also."
Huyler said. "So he suggested that I write
18
about ni\ experiences in the ER t'lir ni\ residene_\'
prujecl.
"I think it's all too easy in medicine to torget that
what you're seeing is remarkable. So the
remarkable becomes mundane. " Hu\ ler said. "Every
once in a while, it's good to sit back and take stock ot the
work we do."
Editor's Note: As of our publication date. The Blood of
Srnini;ers. published by Unixersity of California Press,
can be purchased on the Internet at Amazon.com
( S 1 .^47 ) or BamesandNoble.com ( S 1 .^.% ).
Frank Husler's book. The Blood of Stnmaers. has
recei\ ed numerous review s by literary critics. Among
them are the Boston Globe. The New Yorker, and
Publishers Weekly. Huyler also writes poetry. Some
of his poems have been published in The Athiiuu
Monthly. Poetn. The Georgia Review and the
Carolina Quarterly. At the current time, he is
finishing a book of poems and working on a no\e
"Huyler's w riting is sharp and spare, clean as a
scapel. . . Tliis volume is a modest jewel, a
compact, faceted gem that shines with intelli-
gence. And. like the work of those more senior
doctor/w riter/philosopher kings who precede
him. it proves that even in these days of lawsuits
and HMOs, there are doctors and nurses who
iruK \aluethe lives in their charge."
Boston (ilohc. 9/2^/99
"This haunting, exquisitely observed
collection of medical \'ignettes is much
more than a compilation of odd cases
from the emergency room. Huyler probe
beneath the surface to reveal the marrow
<il his encounters with patients."
I'Khlishcrs Weekly, mo/99
"His uork shows the econonis ami sharp
altention that both jobs |H.R. physician ami poet
demand. "
The AVii Yorker. 9/6/99
19
Women in Leadership
Bv Melissa Matson
Willie the fictional Dr. Quinn may
have been an unusual fixture
in her 180()s setting, women
doctors are commonplace at the turn of the
millennium.
According to the Association of .Amer-
ican Medical Colleges, nearly 50 percent of
medical school applicants are women. As a
result, the number of female physicians is
rising dramatically. And that fact has led to
an increased desire among women to take
on leadership roles in the medical field.
In academic medicine, leadership
opportunities have been relatively slow in
coming. The AAMC found that in 1998,
only 27.4 percent of medical school faculty
members were women. It also found that
"the proportion of women faculty at the
rank of full professor has remained virtually
constant during the past 17 years." Another
interesting fact: the average number of
women department chairs per medical
school is one.
Though there are more women in med-
icine, there are not a proportional number of
women in leadership positions. One possi-
ble reason is women's efforts to balance
career and family. Currently, most tenure
tracks — the traditional way to advance in
academic medicine — do not allow women
to take time off to raise children.
Another possible reason is that women
tend to have fewer networking and mentor-
ing opportunities than men. "Like members
of minority groups, women faculty mem-
bers have a much harder time obtaining the
necessarv mentorine and buildinii net-
works." said Janet Bickel. associate VP in
the AAMC's Division of Institutional Plan-
ning and Development and head of the
Association's Women in Medicine program.
"Men tend to underestimate the extra chal-
lenges that result v\ hen you don't see people
w ho look like you in positions of power."
UNC's School of Medicine is a little
unusual in that female doctors have a vari-
ety of leadership roles, including several
department chairs, deans, division chiefs
and committee heads. Tlw Medical Alumni
Bulletin sat dow n w ith four of them to find
out what their experiences in academic
medicine have been like.
Judith Tintinalli, MD, MS
For Judith Tintinalli. MD. MS, chair of
the Department of Emergenc> Medicine,
eender has made little difference in her
Juclnh Tiniiikilli. MD. MS
career, "rm fortunate to be in a specialt>
that's relatively new. And because of that,
it's open to anyone w ho is sman. \v illin!: to
work hard and good at w hat the\ do." said
Tiniinaili.
She found the same to be true during
her earl\ ciyeer in internal medicine. "I had
no problems because I was a woman during
medical school or residency." Tintinalli
said. "All the way through. I assumed peo-
ple would treat me for w ho I u as."'
■".And now that Tm in a position of
leadership. I make it clear that I ha\ e no
gender agenda." said Tintinalli. "I do think
women ha\e to consider issues that men
ma\ not. but 1 want to see cvcryniu- who is
good get a chance. 1 don't like to sec polar-
ization."'
Her advice to people, male or female,
w ho w ani to enter academic medicine —
develop good clinical skills, learn how to be
a gtKxi administrator, and de\ elop a niche in
scholarh acti\ilies. "In academic medicine,
the path to promotion includes all three."'
said Tintinalli.
Valerie Parisi, MD, MPH
Valerie Parisi. MD. MPH. chair of the
Department of Obstetrics and Gynecology,
thinks that despite the positive changes for
women in medicine, gender is still an issue.
■"For the most part, people in academia
consider themsehes gender neutral." said
Parisi. "But m\ experience in OB/Gyn.
which is a surgical specialty, has been that
gender neutrality is not necessaril\ the
nomi."
Parisi points to the fact that few female
doctors are in positions of "real"' leadership.
"Most women seem to stop in middle man-
agement." said Parisi. "Out of 125 medical
schools, only seven or eight have female
OB/Gyn chairs." The result, says Parisi. is
thai young women have few female role
models.
Like Williams. Parisi is a strong ad\o-
cate of mentoring. "".Mentoring is crucial no
matter who you are." Parisi said. ""And I tell
my students that the\ shouldn't have just
one. ThcN need twii or three w ho can help
w ith different aspects of their career."
Among Parisi "s hopes for future female
phNsicians: greater undersiandmg through-
out academic medicine of the value ot female
leaders and their potential contribution to the
system. ""We don't want to lose gifieil
women to second class jobs." Parisi saiil.
Carol Lucas, Phi)
In the case ot C aroi l.ucas. PhD. chair
of the Department of Biomedical IJigineer-
ing. she is a bit of an oddil\. "\]\ field is
strongly lied to mathematics and engineer-
ing."' said Lucas. "'For that reason. I was
often the (MiI\ woman in ni\ classes or
workplace."
But. said Lucas, that too Is changing.
According to her. biomedical engineering is
a specialty that has proven attract i\e to
women. "You might call it the softer side
ot engineering." Lucas said. "This field has
tangible links to human beings that makes li
more appealing to women than tiadiiumal
engineering."
For Lucas, being a woman in acaiiemic
medicine has been both positive and
nei2ati\e. "'1 call it m\ lite as a token
\alcncl\insi.\ll).\ll'll
woman." saul Lucas. "Vox insiance. \ears
ago. 1 was named president ol .ui interna-
tional organization. That"s because the
members couldn"t decide which of the men
to appoint. Since 1 wastlieonlv worn. in. 1
made the decision an easier one. "
What Lucas tlid find challenging in her
earl) career was securing grants and
publishing scholarl\ articles. '"1 didn"t have
the same network of contacts that main of
my male counterparts iliil." Lucas said.
■"Because ot that. 1 wasn'i able lo liiul out
about as main oppoilunilies."
Now. as one of the oldest women in
her field. Lucas tries to mentor those just
beginning, "rm in a position to help other
women get started." said Lucas. "And now.
there's beginning to be a network that
enables women to talk with and learn from
others who have gone before them."
Roberta Williams, MD
Roberta Williams. MD. chair of the Depart-
ment of Pediatrics, notes that her specialty
w as one of the first to welcome w omen.
"The result is that the younger generation of
pediatricians is predominantly female," said
Williams. "Pediatrics is a very open disci-
pline in which women are encouraged to
move up the ranks. So it"s also a natural fit
for women who have an interest in leader-
ship."
The only barrier Williams sees for
women in academic medicine is the same
lor women of any profession. "The question
is "How will they manage their reproducti\e
\ears?"" said Williams. "1 think that we
need to look at how we can give women an
opportunity to participate in academia and
still have a family. We need to consider
things like job sharing and part-time tenure
tracks." By doing so. believes Williams,
academic medicine can ensure that it v\ ill at-
tract and keep talented people.
She recommends that women interest-
ed in academic medicine do tv\o things.
First, tlnd a mentor. "Women don't take ad-
vantage of mentoring to the degree that men
do." said Williams. "Women need to gi\e
some thought to w ho has the best tools to
help them direct their careers."
Second, assert your needs in the areas
of time, salary and position. "Traditionally,
women sell themselves short." Williams
said. "All too often, women agree on a
salary only to find that a male colleague
makes more. Then they are dissatisfied."
Canil Lucas. PhD
RohcitiiWilluinis.MD
22
Development
Notes
Donations benefit hospital
chaplainc\ program, plastic
surger\ research
It's not often that nionev gi\en to The
Medical Foundation has an ob\ ious and
direct clinical impact. But in the case ot
James and Hannah Bagwell's gift, it does.
In lys^). the Bagwells, who live ni
Washington. North Carolina, established
the William Roberson Bagwell Chaplainc\
Fund in niemorN of their son. who died
that \ear of a brain tumor Bill had ser\ed
as UNC Hospitals' first chaplain dedicated
to patients with HIV and AIDS until his
death. His parents sought to keep their
son's ministr> alive by helping to finance
the chaplain program for that special
patient population.
Last .\o\ember. the Bagwell's added
$50. 000 to the fund. In part, that monev
has gone to support the work of Peter
Mafflv-Kipp. chaplain to AIDS patients at
UNC Hospitals since 1991. "This ministrv
is an essential one in this hospital, and it
would not have been possible w ithout the
Bagwell fund." said Mafflv-Kipp.
On the research side. James Valone.
.MD. a retired plastic surgeon from
Raleigh, and his wife. Ethel. recentl\
committed SI million to The Medical
Foundation to establish the James A. and
Ethel F. Valone Plastic and Reconstructive
Surgerv Research Fund. The generous gift
was stnictured so that part will be donated
outright on an annual basis, and part will
be received from the Valones' estate.
"Dr. and Mrs. Valone and their famil\
are long-time friends of our program, and
they know that we have very strong
clinical and teaching components." saiil
Gerald Sloan. .MD. chief ot the Division of
Plastic Surgerv. "But thev saw what we
need to take our program to the next
level — to strengthen our research "
So the Valones established the fund
to help "kick start" scholarship in the
division. Specificalh. it will allow the
Division of Plastic Surgerv to recruit facultv
to set up significant research projects.
"A wonderful thing about this gift is
that It's unrestricted." Sloan said. "That's
great in teniis of recruitment and great in
teniis of getting residents involved in the
research. External grant funding is so
unpredictable, but the Valone fund will
help keep our research projects going
independent of that."
Centers recei\ e seed grants
from Excellence P'und
Five nationally recogni/ed L'NC
research centers recently received seeil
grants from The Medical Foundation E.xcel-
lence Fund, an annual fund for friends of the
School of Medicine and UNC Hospitals.
Recipients included Lineberger Comprehen-
siv e Cancer Center, the C\ stic Fibrosis/
Pulmonarv Research and Treatment Center,
the Birth Defects Center, the Bow les Center
for Alcohol Studies and the Thurston .Anhri-
tis Research Center.
Each center received a S.'^.OOO seed
grant to fund promising projects — research
leading to new treatments and cures but not
far enough along to receive national funding.
"Seed grants allow researchers to get the data
they need to apply for national grants." said
Shelley Earp. MD. director of the Lineberger
Compreheiisiv e C;uicer Center
"I know I speak for each center when I
sa\ we are thrilled with these gifts." said
Fulton Crew s. PhD. director of the Bow les
Center for .Alcohol Studies. "Tliey w ill help
us continue some v eiy innov ative research."
The Cvstic Fibrosis/Pulmonary
Research and Treatment Center plans to
use its griuit to purchase new equipment for
a researcher who is studying how infection
begins in the lungs of infants diagnosed
with CF
The Birth Defects Center will use the
money to start a newsletter and to help fund
education of health care professionals
regarding folic acid as an effective means
of birth defect prevention.
The Bow les Center for Alcohol Stud-
ies' grant vv ill he used to prepare education/
prevention materials on fetal alcohol
svndrome. the leading cause of biiih defects
including mental retardation.
In addition to these seed grants. The
E-xcellence Fund supports medical student
research awards, a distinguished teaching
professorship, the Family Day program for
families of medical school students, student
travel grants, student lounge renovations
ami other special programs.
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Medical Alumni
WEEKEND
May 4-7, 2000
GENERAL INFORMATION
Accommodations
Blocks of rooms have been reserved at the following area hotels.
Alumni are responsible for making their own reservations by
contacting the hotel directly.
The Sheraton Chapel Hill (formerly the Omni Europa)
919.968-4900 ext 4.^ or I -S()()-.^25-35.^.'S. fax 9m-942-.V'^57.
(Contract: UNC Meilical .Alumni .Accommodations, cut-off date
4/5/00. Rate: $ll9.00-t-».
The Carolina Inn 919-933-2001 or I -800-962-S3 19. fax
919-962-3400. (Contract: Annual Medical School Alumni &
Reunions, cut-off-date 4/14/00. Rate: SI49.00-H).
The Siena Hotel (headquarters for the Class of 1960)
919-929-4000. fax 919-968-6170. (Contract: UNC Medical Alumni
Reunion, cut-off date 3/5/00, Rate: $155-h). Be sure to mention the
contract name when making your reservations and plea.se note the
cut-off dates. Other area hotels: The Hampton Inn (919-968-3000).
The Holiday Inn (9 19-929-2 171). The Best Western University Inn
( 9 1 9-932-2000 ). The Comfort Inn University ( 9 1 9-490-4949 ).
TENTATIVE WEEKEND SCHEDULE
Thursday, May 4
1 1 a.m. Class Reunion Golf - the New Finley Golf
course. Shotgun start. Infomiation regarding
sign-up mailed directly to members ot
reunion classes. Pre-registration is required.
Friday, May 5
9:30 a.m. -3 p.m. Registration Desk Open. Carolina Club/
George Watts Hill Alumni Center.
L'NC campus.
10 a.m. -Noon ,\nnual Business Meeting. Dowd Room.
Carolina Club. (All Alumni Welcome)
Election of officers and councillors. Lunch
provided for attendees following the meeting
by pre-registration onl\.
Noon- 1 p.m. National Loyalty Fund Steering Committee.
Peebles Room. Carolina Club ( Lunch included ).
1:.W- 2:30 p.m. The Fighteenth .Annual Spicer-Brecken-
ridge Memorial Lecture. 103 Ben-yhill Hall.
Shuttle bus ser\ice will be pro\ idcd from the
Alumni Center.
3-5 p.m.
Speaker: M. Therese Southgate. MD. .Art
Editor J on null af the Aincncan Mcdual
Association.
Fndowment Board Meeting (Selection of
2()()0-20()l grant recipients) Dmvd Room.
Carolina Club.
Reception and Annual Alumni Banquet
( Ptv-n'siistnition leqitiied)
Alumni Hall I. II. III. Carolina Club. George
Watts Hill Alumni Center. UNC Campus.
6:30 p.m. Champagne & Wine Reception
7:15 p.m. Dinner Seating. *Recognition of alumni
fundraising campaigns 'Presentation of
Distinguished Service Awards and Distin-
guished Faculty Award "Recognition of
recently retired faculty.
Saturday. May 6
8 a.m.- 12:30 p.m.
CMF: Clinical Application of Anticoagula-
tion Therapy
*
CLASS REUNIONS
Class of 1945 Saturday. May 6. Carolina Inn. Social &
Dinner
Class of 1 950 Thursdas. May 4. Cocktails & Dinner
Class of 1 955 Saturday. May 6. Hope Valley Country Club.
Durham. Social & Dinner
Class of 1960 Saturday. May 6. The Siena Hotel. Tuscany
Room. Social & Dinner
Class of 1 965 Saturday. May 6. Cocktails & Dinner
Classof 1970 Saturday. May 6. Carolina Club. Cocktails
& Dinner
Class of 1 975 Saturday. May 6
Class of 1980 Saturday. May 6
Classof 1985 Saturday. May6. Anderson Park. Carrboro.
Picnic
Class of 1 990 Saturday. May 6. The Carolina Inn. Reception
■All schedules below are tentative. Final Plans included in class
mailiiiiis.
24
President's
Letter
Greetings Fellow Alumni.
B\ the time \ou receive this issue of the
Bulletin, those of us fortunate enough - or
ill-fated enough, depending on your point
of view - to have experienced the snow -
slomi of the centun, will have returned to
our usual activities and daily routine.
The severe weather caused the cancel-
lation of the Wake County Deans Recep-
tion, hut others are scheduled in Guilford.
Forsyth. Mecklenburg and Cumberland (a
first! ) counties as well as in .Atlanta. These
are outstanding opportunities to sociali/e
with fellow alumni and others w ho are
significant supporters of the medical
school. It also offers a chance to get the
current scoop on the state of the school
and renew a sense of connectedness to
each other and Chapel Hill. John Foust
will likely remind you that your ri\al
county in the Loyaltv Fund Campaign is
set to triumph over you in the current
drive. I hope to have the pleasure of seeing
you at a reception in your area.
The highlight of the \ear for the Gener-
al Alumni Association is the Spring
Alumni Weekend. Reunion committees
are busy planning a festive time for their
classes ( see page 24 ).
Outstanding alumni and facultv will be
recogni/eti at the banquet, which also will
serve as the moment of truth for the Lo\ -
alty Funti Campaign. This is a wonderful
time to be in Chapel Hill and I hope man\
of you can come. One of the opportunities
my office affords is to participate in meet-
ings of the Board of the General Alumni
Association. This is a dedicated group of
Tar Heels who oversee a sers effective
organization that provides excellent
service to alumni.
Among other enjoyable activities at the
winter meetings w as the opportunitv to re-
view the master plan for the L'NC campus
for the next decades (as rev iewed else-
w here in the Bullciin). The concept is
wonderful. The execution may not be
complete in my lifetime, but the
existence of this commitment is a great
comfort to those of us w ho treasure the
Chapel Hill of ourfomiative years.
Well, enough of this sentimental
rambling (a prerogative of advancing
vears). Hope to see vou in Chapel Hill in
Mav.
Gordon B. LeGrand. MD -65
CME/Alumni Calendar
March 24-26. 2000 — Chapel Hill
Clinical Relevance of Medicinal Herbs and Nutritional
Supplements in the Management ot Major Medical Problems
March 26-April 1, 2000 — Chapel Hill
Physicians Medical Management Program. Kenan-Ragler
Business School
April 5-7, 2000 — Chapel Hill
24th Annual Internal Medicine Conference
April II, 2000 — Chapel Hill
Emergency Medicine Research Forum
April 29-30, 2000 — Chapel Hill
I5th Annual Meeting of the Glomerular Disease Collaborative
Network
May 4-7, 2000 — Chapel Hill
UNC Medical Alumni Weekend
For moie infonnalion about CME courses, contact the Office of
Continuing Medical Education. (919) 962-21 18. or toll-free
through the Consultation Center. (800) 862-6264. To contact
the Alumni Affairs office, call (919) 962-6786 or e-mail
medical_alumni@nied.unc.edu.
Estate Planning Notice
Many individuals would like to make a major gift to the
UNC medical center, but cannot commit current assets /
for such a purpose. Through a will, however, anyone
can make a more significant gift than they might ever
have thought possible by designating a specific sum, a
percentage, or the residue of their estate for the benefit
of the medical center.
To provide a bequest, simply include a paragraph in
your will naming The Medical Foundation of North
Carolina, Inc. as a beneficiary. For example:
"/ give, devise and bequeath (the sum of$ ) or
( % of my estate) or (the residue of my estate)
to The Medical Foundation of North Carolina, Inc..
a 501(C)(3) created to maintain fimds for the UNC
medical center with principal offices located at 880
Airport Road, Chapel Hill, North Carolina!'
This language creates an unrestricted bequest for use by
the medical center when and where the need is greatest,
or you may specify that your gift be used for a particular
purpose.
For further information on bequests, contact Jane
McNeer at (919) 966-1201, (800) 962-2543, or
jmcneer@email.unc.edu.
PERIODICALS DEPARTMENT
HEALTH SCIENCES LIBRARY
CAROLINA CAMPUS 7585
Nonprofit Organizatiim
U.S. Postage
PAID
Chapel Hill. NC
Permit No. 24
Medical Alumni
BULLEnN
Sdiool of Medicine, University of North Carolina at Chapel Hill
i
Dean's
Page
The missit)!! ul Ihe UNC School ol
Medicine reminds us thai w c
were created to improve the
health ol the people of North
Carolina.
For the past 27 years, one of the ua\s our
niissit)n has been most tangibly
realized has been through our involvement
with and leadership of the Area Health Edu-
cation Centers (AHEC) Program.
AHEC was created by a group of vision-
ary leaders to address the stubborn prob-
lems of both the shortage and
maldistribution of primary care physicians
and other healthcare providers in our state.
From the outset, we realized this ct)uld not
be a venture of our .School alone, but wouki
require close ccdiaboration with all
five UNC-CH health affairs schools, as
well as Ihe other acatlemic health centers in
the state.
Working with our colleagues and using
AHEC as the bridge, we have been able to
provide community-based training experi-
ences for our students and residents, while
offering our expertise to practicing profes-
sionals in even the most rural and under-
served communities.
Today, the AHEC program remains the
linchpin of a broad anay of educational ini-
tiatives designed to prepare physicians and
other healthcare pro\ iders to meet the needs
of the stale.
For our School, it would be impossible to
have a class size of 1 60 without the eapacils
the AHECs and the AHEC faculty afford us.
More than 40 percent of the clinical training
of each medical student occurs in an AHEC
setting, and AHEC rotations continue to re-
ceive evaluations by students that are at or
near the top of all clinical experiences.
Reading through student evaluations gives a
sense of the importance these experiences
play in the life of UNC medical students.
Recent examples include comments such
as "I learned so much about primary care
medicine. It was a great experience." or ""the
attendings really enjoy teaching and al-
lowed me the right balance between autono-
m\ aiul supervision. ..this was the best
experience t)f m_\ medical career thus far."
AHEC also pro\ ides a means by which
the School can fulfill its ser\ ice mission.
Last year, more than 440 specialty clinics
were pro\ ided by our faculty in towns and
cities across that state that would not other-
wise have priority access to such sub-spe-
cialty care. In addition, our faculty taught
some .^.'iO Continuing Medical Education
programs and provided technical assistance
to countless health-care pro\ iders
AHEC also offers the iiili astriiciure
through which we can resptind rapidl\ to
urgent healthcare needs when they arise. At
the time of the flooding in eastern North
Carolina last fall. AHEC proved a vital re-
source for faculty who offered clinical ser-
\ ices to communities in the affected areas.
Through regional AHECs. we also were
able to pro\ ide training programs for
health-care pro\ Iders and other human
service workers dealing w ith the emotional
aftemiath of the tragedy.
AHECs capacity to adapt to the chang-
ing needs of the state has been critical to its
success through the years. Currently the
School of Medicine and the other health
atfairs schools are working closely with
AHEC on a new strategic plan for 2001-
2004. As we build on our core programs for
students, residents and practicing
health professionals. I anticipate this plan-
ning process will help shape our opportuni-
ties to respoiul more effectively to
important concerns.
We will address such issues as increasing
the number of undeirepresented minorities
in medicine and other health careers; using
infomiation technology to improve our edu-
cational programs and increase access to
health care; strengthening our primary care
and prevention programs; and improving
our efforts to give patients and the general
pLiblic better information about their health
and ways to enhance it.
The North Carolina AHEC program has
become a standard of excellence for similar
efforts throughout the nation. It provides our
Schixil of Medicine with a statewide class-
room for students, residents and healthcare
practitioners of all types.
As AHEC engages in a planiung process
that sets its course tor the next four years. I
am confident it will demonstrate once again
how careful attention to the needs of the
state, high-quality education programs and
cooperation w ith other institutions can be
combined to achieve a farsighted and pur-
poseful fulfillment of the School of Medi-
cine's mission.
Ofl}d^ L- &tufC
Jcffivx L. Hiuipl. Stn
Dean. Sclu><:l„t Mi, Heme
Medical Alumni
Association Officers
President
Gordon B. LeGiand. MD "65
Rcileii;li
President-Elect
PaulE. Viser.MD"84
Clinlon
Vice President
Thomas J. K(H»nt/. MD "66
Wliistfiii-Stilciii
Secretar>
Ralph L. "Wall Jr.. MD "78
Wiiisidii-Siilc'iii
Treasurer
William M. Hcrndon. Jr.. MD "81
Charlotlc
Editorial Staff
John W. Stokes
Vice President. Fiihlic Ajfairs &
Marketing
Dcbra Pierce
Mdiuiiiini; Eclilar
Michele Blevins. Katherine Kopp.
Leslie H. Lang. Melissa Malson.
Karen Stinneford. Lynn Wootcn
Contrihiitiiiii Wrilers
Dan Cra\\l(ird ipus. 14. l.-^i
Ja\ NUmgunKpgs. 6. 10. 1 1.20.2!)
I'hoUniniphcrs
The Meilu at Ahimiii Hulliim is piihlisheil lour liiiicv
annually by ihc L'NC-Chaix-I Hill Medical .■\lunini
A.ss<x;ialion. Chapel Hill. NC 275 14. Poslajic is p.ml
by ihe non-pnifit associatinn through I'.S. Postal
Permit No. 24. Address correspondence to the editi u.
Office ol Medical Center Public Affairs. .School , il
Medicine. CBWTNIO. University of North ( ■.irolm.i.
Chapel Hill. NC 275 14
Medical Alumni
BULLETIN
School of Medicine, Iniversitv ot North CaroUna at Chapel Hill
Contents
Features
.A Natural t'orL'NC Neuroscience 6
Miiiniu Protilc: Daniel Biim n, MD, 't>5 S
UNC Surgeons Pertorni .Slate's [-iisi "Doniino" LiverTransplanl 10
L'NC Health C;u"c Aequires Rex Healthcare 12
Match Da> 2()()() and Pearls otWisLloin 14
.AHEC: Taking Medicine lo Ni>nh Carolina's Coinniunilies 16
Kids allNC Hospitals rseC'ompulers To ralkWilhOlher Sick C'hildien IS
l-Miih\ Profile: Fuller Award Winner Harve> Hanirick. MD 20
Departments
Dean's Pace Inside Front Cover
Research Briefs 2
NewsBriels 4
lacullv Notes 22
Development Notes 24
I'lesuient's Letter Inside Back Cover
C.\lF./.\lunini Calendar Back Cover
Oinlh ( n\,i Ihc Dull nil,. II led An innn\.ili\c li\ci li. mspl, ml oilers mnic Ik >|X- h'l iliIkhIs
in,ol,,l>s .l„\ \Uur.;i,m
Research
Briefs
UNC, Duke, starting search
for osteoarthritis genes
It's not dilTicLilt to I'lnd a I'amily in whicli
generation after generation has struggled
w ith the same inherited disease. The ehal-
lenge is finding the genetie hnk to understand
how iihiesses. sueh as osteoarthritis, are
passed down Iroiii parents to their otTspring.
An international researeh network com-
posed ot'se\en unisersity medical institutions
including UNC"s Thurston Arthritis Re-
search Center and Duke University Medical
Center have just begun the largest study ever
to look tor that link, the genetic susceptibility
toosteoailhritis.
The most common form of arthritis, os-
teoailhritis is a chronic conditiim that allects
more than 21 million Americans. B\ anaK/-
ing DN.A and health histories from man\ pa-
tients, researchers believe they vv ill better
understand the role that one or more genes
play in the condition's development. The
goal is to find new and more etfective medi-
cines. The academic research institutions are
v\i>rking together with the Center for Human
Genetics at Duke and Glaxo Wellcome, a
pharmaceutical company.
/■'('/■ //;<■ ///// \!(>n, sec littp://\v\v\\.iinc.cdii
/ncws/iicwsscry/icscuivh/jiinliinl IM>'-)'->.l}lin.
Study finds no evidence that
hormone benefits autism
Parents will go to great lengths to help
children w ith illnesses, including trying the
latest well-publicized treatments regardless
of w hether they "v e been prov en effectiv e. But
if a theiapv sounds loo good to be true, it usu-
ally is.
A new' study, which appeared in the New
EugUmdJdiirnal of Medicine, offers a prime
example of this. Contrarv' to w hat early pub-
licitv suggested. North Carolina researchers
found no ev idence that a single dose of the
synthetic human hormone secretin benefited
children w ith autism.
In a well-controlled study of 60 children,
half of whom received synthetic secretin and
half of whom received an inactive salt solu-
tion, scientists could tell no difference be-
tween the groups when the studv ended. The
investigation was double-blind, meaning that
neither clinicians nor parents knew w hicli of
the two treatments the children received until
ev aluations were complete.
lor more infomiation. see hnp./Annv.uiic.
edi(/ne\vs/newsscn/reseairMiodfisl\l2SW.Imn.
UNC scientist finds smallest
number of genes needed for
organism's survival
The minimum number of protein-producing
genes a single-celled org;misni needs to sunive
and reproduce in the laboratory is somewhere
between 265 and 350, according to new re-
search directed by a top UNC scientist.
L'sing a technique know n as global trans-
poson mutagenesis. Clyde A. Hutchison III.
PhD. professor of microbiology, and col-
leagues at The Institute for Genomic Re-
search in Rockv ille. Md.. found that roughlv
a third of the genes in the disease-causing
Mycoplasma genitalium were unnecessary
tor the bacterium's surv iv al.
The technique — a process of elimination
— involved randomly inserting bits of
unrelated DNA into the middle of genes to
disrupt their function and see if the organism
thrived aiiyvv ay.
.Stich research is a significant step forward
111 creating minimal, tailor-made lite forms
that can be further altered for such purposes
as making biologically activ e agents for treat-
ing illness. Hutchison said. More immediate-
Iv. it boosts scientists" basic understanding of
the question. "What is life .'"
For nunc infonuation. see hup: //www: unc.
cdii/iHws/iiewssen/researcMmuh 12999.htm.
UNC selected as mutant
mouse resource center
The National Institutes of Health selected
UNC as one of tw o Regional Mutant Mouse
Resource Centers in the nation. The new cen-
ter will receive a grant of S660.000 annually
ov er fiv e years.
UNC and the University of California at
Dav is w ill facilitate more w idespread use of
mouse models in basic and translational re-
search throutihout the countrv. Such models
have revolutionized scientists' ability to
probe mammalian biology and disease and
hav e become a v akiable resource.
The new centers will expand the already
strained capabilities of Jackson Laboratories
in Bar Harbor. Maine, to characterize,
maintain and distribute an ever-growing
anav of mutant mouse models to the research
community.
"One of the problems is that people can
generate lots of models, but these won't be
accessible w ithout a repository w here they
can be quality controlled, checked out and
distributed." said Terrv Van Dv ke. PhD. pro-
fessor of biochemistry and biophv sics.
For more information, see liup://\\ww:une.
edii/ne\\s/ne\\ssen/resecinli/m(Hisel2l7W.liim.
Cooperation marks new era i
of cancer research
In the new millennium, cooperation ■.—
rather than keen-eyed competition — may
signal a new era of federally funded research
lor the nation's top scientists who develop
and study mouse models of cancer.
In a bold strategy, a UNC scientist will
share the helm of the Mouse Models of
Human Cancer Consortium, a cooperative of
14 university-based research teams from
around the nation, each indiv idually funded
bv the National Cancer Institute ( NCI ).
"It's reallv ven exciting — it's a paradigm
shift in the w ay most people do science." said
Teny Van Dvke. PhD. professor of biochem-
istrv and biophysics. "Most who do science
do so independently, and are worried about
the competition and who gets the credit. Now
each team will have some money to work on
their own animal models, and pursue their
own indiv idual ideas, but will also participate
in a larger scale cooperative group.
"There will be extensive sharing of ideas,
results and reagents." she added.
Molecular fats prevent nerve
sheath abnormality
.A studv led bv scientists at UNC points
to a group of fats crucial to the proper fomia-
tion of the myelin sheath surrounding
nerv e fibers. I
Although the new trndings ha\e no direct
clinical implications tor human disease. the\
help sohe a scientific puzzle while adding
new know ledge to the molecular biolog\ of
iinelin and diseases of m\elin loss, parlicu-
larh multiple sclerosis.
M\elm. which is 3()-pcrcent protcm and
7()-percent lipid — or fat — tonus the multi-
membrane shield that surrounds ner\e
axons, hair-like extensions of nene cells that
snake off and make connections w iih other
nerve cells. These m\elinaied connections
fonn the u iring circuitr\ of both the central
nervous systems, which includes the brain
and spinal cord, and the peripheral nervous
sxsiem.
Foi till' full article, sec lntp://\\w\\.um .ccIk
/ih"n \/iic\\ sscir/ivseanli/iiiycliii 1 2 1 Jyy.litiii.
.\voiding vitamins A, E might
improN e cancer tlierapv
X'uamins .A and H. w hich normallv boost
human health in numerous ways, also appear
to keep cancer cells from dying through the
natural protective process scientists call
apoptosis. new UNC research show s.
.As a result, giving patients those vitamins
niav prevent cancer cells from self-destruct-
ing and work against cancer therapv. scien-
tists say.
nie UNC researchers presented their find-
ings at the .•\merican .Society for Cell Biolo-
gv's annual meeting in Washington. D.C.
Rudolph .Salganik. PhD. research professor
of nutrition, and Terrv Van Dvke. PhD. pro-
fessor of biochemistrv and biophvsics. di-
rected the studies.
"We believe this work is important be-
cause it ma\ make cancer treatments more
effective." Salganik said, "it suggests that
cancer patients, especiallv those undergoing
chemotherapy or radiation therapv. mav do
better on an antioxidant-depleted diet."
hiiniiiirc liitdniuitidii \cc liltp://\\'\\M:iiiic.cdii
/twws/iwwsscn/rcHiin li/viiiiinik l2lJW.Iitiii.
Newer oral contraceptive
may be less liarmful for
women smolders
Oral conlraceptivcs arc known to increase
the risk of heart problems for smokers, aiul
new research at UNC suggests that might be
due in part to the specific Ivpe of hormones
contained in "the pill."
Older "second-generation" oral contra-
ceptives have a higher androgenic coiilenl
because of the tvpe of progesterone hormone
used w hen compared to new er "third-genera-
tion" fonnulations.
For all women, older oral contraceptives
prtiduced higher blood pressures and more
resistance to blood flow inside blood vessels
during stressful situations, the UNC suidv
showed.
.A report on the findings a|ipcaicd in the
Januan issue of Ohsictrics and Gyiiecoloi;}.
■Authors include psv chology graduate stu-
dent Patricia Straneva and Susan (iirdler.
PhD. assistant professor of psychiatrv
For mine information, sec hllp://w\vu:tini .
eihi/ne\v.\/ne\\sseiv/ivseaiili/i;inllcii)l()^K).litm.
Cystic fibrosis experiments
offer hope for improv ed
treatments
.Although not vet ready to trv their new
technique in patients. U.NC scientists have
successfulK repaired a genetic problem that
accounts for a form of cystic fibrosis com-
monly seen in patients of European Jewish
descent.
Kenneth Friedman. PhD. research lellow
in pathologv and laboratory medicine, and
Rvszard Kole. PhD. professor of phaniiacol-
ogv. dev eloped the method to correct a miita-
tion involv ing unnecessarv information
inside a gene. When that gene is imperfect,
cystic fibrosis results.
The two conducted the research in collab-
oration with UNC's Lawrence Silverman.
MD. and Michael Know les. MD. and Duke
Universitv 's Jonathan Cohn. MD. and tech-
nician Jolanta Kole.
"This work builds on a strategy first ex-
plored by Dr. Kole in his studies of beta-tha-
lassemia. a genetic disease often seen in
Mediterranean and some Asian couniiics
and involv ing defective hemoglobin mole-
cules that lead to red blood cell destruclion in
bone marrow." Friedman said. "We applied
his method to a cvstic fibrosis gene mulalioii
discovered here at L:NCin iw"i."
/■(// the lull \liir\. sec hltp://\\\\\\Aiiic.cdii
/ni'w \/iic\\\si n/rc\C(inli/li'lcmiiJI2U)W,liiiii.
Experts to study informed
consent in national gene
transfer research
Investigating ethical issues surrounding
recent ami upcoming genetic discoveries w ill
be Ihe L'oal (da new S')7.S.()(I(I National
Human Genome Research Institute award to
L'NC tacultv members.
Gail Henderson. PhD. and Nancv King.
JD. both professors of social medicine,
will lead the three-vear elTort. sponsored b>
the institute's Ethical. Legal and Social Im-
plications of the Human Genome Project
program.
"\\ hen Dr. James Watson set up the
Human Genome Project, he required that a
certain percentage of its budget be set aside
to fund studies of the genome project's ethi-
cal, legal and social implications since it
raised so manv questions." Henderson
said. "Our work relates to how people under-
stand genetic research in tcinis of the
consent process,
"We're planning to invesiigalc how bene-
fits are described and understood in gene
transfer studies, which just about everybody
calls gene therapy." she said. "People think of
these studies as therapy but they are not at all.
The> are reallv just earlv research that we
hope will eventualh lead to better treat-
ments."
For the full slorw sec lutp://\\\\\y.unc.cdu
/nms/nc\\sscir/resciucli/licndciill llXXI.htm.
UNC study may help clarify
how cells grow
.A studv led bv a UNC scientist sheds new
light on the process of cell growth regulation.
The studv. which focuses on ihe complex
network of biochemical signals between pro-
teins and en/v mes w ithin cells, helps clarify
how those signals initiate or limit cell
growth.
.Although still too basic for clinical use.
the findings suggest the possibility of new
tlrugs that wiiuld target specific growth-in-
tlucing molecules within cancer cells. A re-
port of the studv appeared in the science
journal Wuun .
Lee Graves. PhD. assistant protessor of
pharmacologv and the suidv s principal m-
\ esiigalor. saiil the cii/v me M.AP kinase
(M.APKi IS a kcv component of a signaling
palhwav iniliatetl bv growth factors.
"This IS just one of manv signaling |ialh-
wavs. but we know it's essential for growth."
he said. "So the kcv question has been, w hat
are the specific targets of MAP kinase'.' That
is. what are the impoilant things it does, and
how doe^ It regulate cell growth'.'"
lor more uiloriuation. see http://\\\\\\.uni .
edii/neus/ne\\ssen/rcseanli/,cll<)l2lKXI.hinL
News
Briefs
Medical school to create
genetics center
The School of Medicine will receive $2.6
million over four years from the Howard
Hughes Medical Institute to help de\ elop and
staff a new genetics center.
"The genetics center will complement ex-
isting research strengths at Carolina in the
studs of mouse models of diseases, genetics
of model organisms, cancer research and
chnical genetics." said Williatn F. Mar/luff.
PhD. executive a.ssociate dean for research.
"The money will establish the genomics
core technologies we need on campus, in-
cluding a chromosome imaging facility for
detecting alterations in cancer, as well as ab-
normalities in genetic diseases." he said.
"It will also be used for recruiting four
young faculty members working in mam-
malian genetics."
Ot \()5 U.S. medical schools competing
for the Howard Hughes grants. L'NC w as
among 41 w inncrs. Awiirds ranged from $1 .6
million toS4 million.
NIH awards UNC, Duke $21
million to boost care for AIDS
patients, research
AIDS specialists at UNC and Duke will
iecei\'e S2I million from the National Insti-
tute of Allergv and Infectious Diseases over
the next fixe years to continue their battle
against the deadly illness.
The money is part of renewed national
Adult AIDS Clinical Tnals Group ( A ACTG 1
funding. It w ill suppoil care for people li\ ing
w ith .AIDS across North Carolina and clini-
cal trials that already have resulted in far
more effective treatments than were first
axailable and promise further medical
progress, the physicians say.
"Since the beginning of the AIDS epidem-
ic, the AACTG has made enormous contri-
butions in helping people with HIV li\e
dramatically longer and healthier li\'es." said
Anthonv S. Fauci. MD. director of the insti-
tute. ".A.ACTG studies ha\e been and will
continue to be an invaluable source of scien-
tific data, significantly advancing our ability
to treat HIV."
UNC's effort, led by Charles van dcr
Horst. MD. professor of medicine, and
Joseph Eron. MD. associate professor of
medicine, will get $12.5 million. Duke's
effort, directed by John Bartlett. MD. associ-
ate professor of medicine, will receive
$8. .5 million.
New program leaders named
at cancer center
Marci Campbell. PhD. and Andrew Ol-
shan. PhD. have been appointed as program
leaders at the Lineberger Comprehensi\e
Cancer Center.
Campbell, assistant professor of nutrition.
will lead the Cancer Prevention and Control
Program.
This program works v\ ith communities,
health care pro\ iders. schools and other
agencies to promote adoption of healthy be-
haviors — including diet, smoking cessation,
physical activity and cancer screening —
with an emphasis on acti\ ities in rural, un-
derser\ed and minority populatiiins.
Scientists also are investigating a wide va-
riety of other topics, including issues faced
by cancer survivors and new approaches to
cancer prevention.
Olshan. associate professor of epidemiol-
ogy and research associate professor of
surgery, will lead the Cancer Epidemiology
Program.
Researchers in the program are in\estigat-
ing disease patterns in the population to iso-
late possible causes of cancer, such as
lifestyle and the en\ ironment. as well as to
identify groups at high risk for cancer.
In combining epidemiology with basic sci-
ence using molecular and genetic en\ iron-
mental/ lifcstv le exposures.
UNC performs videoscopic
surgery
For millions of Americans, heartburn isn't
just an occasional aggravation. Rather, it is
an cNcrvdav misery that forces them to con-
tinually consume over-the-counter antacids
and prescription medications and keeps them
aw ake at night.
Now those painful days and sleepless
nights can be eradicated, thanks to a video-
scopic surgical procedure being performed
by physicians at UNC.
"Estimates show that l<S million people
in the United States suffer from chronic
heartburn or what is known as gastroe-
sophageal reflux disease, or GERD." said
Mark J. Koruda. MD. professor of surgery
and nutrition.
"While antacids and medications may re-
lieve symptoms for occasional heartburn,
they don't offer comfort for some one million
chronic sufferers. For these folks, videoscop-
ic surgery can be a long-term solution to an
everydav problem. "
In the \ ideoscopic surgical procedure now
being offered at UNC Hospitals, the physi-
cian makes fi\ e to six small incisions — each
less than one inch — to make room for spe-
cial surgical instruments, including the la-
pai\)scope.
While the videoscopic procedure is new.
the surgery itself is not — it has been around
since the 1930s. But traditional surgery re-
quired surgeons to make a long incision in
the abdomen, a painful operation from w hich
patients took a long time to recov er.
Lineberger awarded
$25.3 million renewal
grant from NCI
The Lineberger Comprehensive Cancer
Center has received a five-year. $25.3 million
grant from the National Cancer Institute to
renew support for its cancer research pro-
grams.
The amount represents a 94 percent in-
crease from the center's previous five-year
grant, one of the largest increases ever award-
ed b\ the institute's cancer centers program.
All of the funds will be used at UNC. making
this grant one of the largest ever awarded for
research at the universit>.
"The Lineberger Center has done a re-
markable job of bringing taeuh\ together
from ail the health affairs schools, and in-
creasingl\. other parts of the campus, to bear
upon the problem of cancer." said Jeftre\
Houpt. MD. dean of the school of medicine.
"Its intcrdiscipiinars research efforts are
ground-breaking."'
Said H. .Shellon Earji. MD. center director.
"In the past live years, the I'NC Lincbcrger
Center has grown dramaticall}. fashioning
inultidisciplin;u-\ clinical care programs \\ ilh
LNC Hospitals and UNC Heahh Care as
well as conducting outstanding clinical, pub-
lic health and basic cancer research. National
recognition of our superb scientists and
ph\ sicians has increased commensurately.
With this renewal grant. NCI has recognized
the qualit\ and cimtinued promise of our re-
search and clinical efforts."
UNC Hospice excels during
recent Joint Commission
accreditation
LNC Hospice, part of the L^NC Health
Care System, receixed the highest designa-
tion possible during a recent re\ iew by the
Joint Commission on Accreditation of
I Icalthcarc Organizations.
Preliminar\ findings from the accrcilita-
tion re\iew showed that LNC Hos|iicc
scored yy out of I (K) points.
This marked the first time L'NC Hospice
hud undergone re\ iew by the Joint Commis-
sion, an independent, not-for-profit organiza-
tion that is the world's leading health-care
standards setting and accrediting bod\.
LjNC Hospice, formerlx' Hospice ol
Chatham County, has scrvcil tcrininalK ill
patients and their families for \h \cais. flic
l.^-emplosec organization became pari ol
CNC Health Care in .April \W-) and scr\cs
Chatham and Orange counties.
Judy Li pa. executive director of INC
Hospice, said the Joint Commission accredi-
tation lends even more credibility to an orga-
nization that already prides itself on
deliverin;: evcelleni care.
".Although more and more hospices are
seeking Joint Commission accreditation,
only about 5 percent complete their initial
surveys at the same high level L'NC did. so
we obv iouslv are excited about that." she
said.
To earn and maintain accreditation, an or-
ganization must undergo an on-site survev by
a Joint Commission survev learn al least
everv three vcars.
Federal funds awarded for
training clinical researchers
The School of Medicine has won federal
funds to train some of its best and brightest
young doctors for careers in clinical research.
The Clinical Research Cumculum .-\w.ird
comes from the National Institutes of Health.
The award helps prov ide an in-depth two-
year training program for eight to 10 junior
faculty, each of whom is committed to a ca-
reer as a clinical investigator, according to
Eugene P. Orringer. MD. executive associate
dean fiir facuhy affairs.
"Over the last decade, there has been a
dearth of young physicians who pursue clini-
cal research as their career goal. It's not a
local problem, but rather a national problem."
he said. "The NIH created this award to pio-
V ide institutions such as UNC w ith the sii|i-
port for the infrastructure necessarv to tram
these young people."
L'NC was one of .^.'i medical iiisiiiLilions to
win the award, which pro\ ides S2()().()(K) per
vear over five years and is renewable. For
purposes of this award, clinical research in-
cludes patient-oriented research, epidemio-
logic and behavioral studies, ami
(nitcomes-oricnled heahh scrv ices research.
.\l Carolina, trainees will lake courses in
those areas through the schools of medicine,
public health and pharmacv. A new Iv de-
signed seminar program locuseil on ilrug ile-
velopment will supplement those courses.
.All trainees will also design antl carrv out a
comprehensive clinical research pio|ccl
Al the heart of the program is a novel men
loring system in which senior lacullv mem
hers work closelv with Irainees. helpiii'j llieiii
w ith coursework and research, and w ith set-
ting and then achiev ing their long-term ca-
reer goals.
"We have created a program that has both
breadth and depth." Orringer said. "We are
paiiicularlv pleased with the close exposure
each trainee will gel to faciiltv members and
other trainees."
He added that most of the trainees will
have written a NIH grant pi\)|iosal hv the end
ol their second y ear in the program.
But. Orringer added, while NIH funding
supports the program's infrastructure - in-
cluding a portion of the salai v for senior fac-
ulty inxohed - it does luu pro\ ide the
stipends needed to pay the trainees. This
meant reaching out to attract additional funds
from other sources.
"We knew that wiilnn the next decade or
SI) a lot of clinical research would involve
drug devektpment. including clinical trials."'
said Orringer. "So w ith that locus. I felt we
could go to industry and ask tor help lo su|v
port some of the trainees."'
.And so far the plan has mel w iili success,
l-'inancial support for trainees eniollcd in ihe
new program has been obtained from the
phannaceutical giant Eli Lilly and Company,
from Pharmaceutical Product Development
Incoiporated (PPD-Pharniaco). a clinical re-
search organization, and from the American
Academv t)f Phannaceutical Phvsiciaiis.
A Natural for
UNC Neuroscience
/);: Sniilcr ilistiisscs a computer imuf^c with Dr. Ahiiui Jiukiiuiii.
By Leslie H. Lang
Williuiii "Bill" Snider has an
ambitious goal; He wants to
make UNC a major national
plaser in 21st-century neuro-
science reseaivh.
To that end, this tall, atfabie. soft-spoken
native of western Kentucky must don several
hats — that of college recruiter, \isionary.
fund raiser, program director, and. of course,
scientist.
For the new head of UNC's Neuroscience
Research Center, that last cluipeau is a natur-
al fit. A pioneer in neuronal growth factor re-
search. Snider and his work on proteins that
reijulate the survival and erovvth of neurons
are lamiliar to most senior scientists in the
field, indeed, his research reputation had qui-
etlv si)lidified during a 16-year tenure at
Washington University in St. Louis.
And when it came to selecting a top scien-
tist who could also toot the Tar Heel mega-
phone for neuroscience recruiting and
fund-raising. Snider's UNC legacy helped
make him a natural choice. Both his mother
and her sister earned degrees in Chapel
Hill, and Snider earned both his bachelor's of
science in niatheniatics and medical degrees
here.
"1 grew up in this little town in Keiituckv
called Hopkinsv ille. and for reasons I don't
fulK understand, my grandfather sent two of
his daughters dow n to Chapel Hill." he said.
"And this was back in the 19.^()s when there
were few w omen here. So my mother and her
sister were ainong the first women to do their
last two years of college at UNC."
While her son was excelling in science
duiing high school. Snider's mom made him
aware of the National Science Foundation
prizes for talented science students.
These were intensive summer programs in
science education. Her suggestion that he try
for one held at UNC might have been an indi-
cation that she smiled at the memory of her
Carolina days.
"So that's how 1 first got here the summer
after my junior year in high school, and 1
just loved it." Snider said. "Later I applied to
and got accepted by UNC and Duke. So I
picked UNC."
The furnier math major eredits a ph\ Mcal
eheniistrx professor tor introducing him
lo the biological world of nerve axons
and synapses.
"Lee Pederson gave me a book by Sir
Bernard Kat? called Ner\e Muscle Synapse."'
he said. "It's a famous book about the
process of synaptic transmission at
the neuromuscular junction, the synapse
between ner\es and muscle. And 1 found it
fascinating. It seemed to have a \ery logical
and quantitati\e aspect that w as also appeal-
ing to me.'"
During his first year in medical schoiil.
Snider was exposed to neurobiology through
a course taught by Edward Perl. Mf^. cur-
rentU Sarah Graham Kenan Professor of
Cellular and .Molecular Phy siology at UNC.
In 1971. Perl was recniited to UNC from the
University of Utah to strengthen neuro-
science at Chapel Hill. It was Perl who
helped recruit his former student to take over
the helm of UNC's Neuroscience Research
Center
"The combination of exposure in neurobi-
ology in that course, and my tascinalion w ith
neurosciences through pre\ious con\ersa-
tions with Dr. Pederson. just did it for me that
1 was going to be in\()l\ed in this field."
Snider said. ""I think a lot of us with interest
in biological science struggled with the issue
of w hether to pursue graduate training or
medical school training. For many, this has
been solved by the combined .MD-PhD pro-
gram. But this option didn"t exist \^hen I was
at L'NC. 1 might add that Dr. Perl also strug-
gled with this issue."
So lascinated b\ neurosciences was
Snider that he took a y ear off after his tlrsi
year in medical school to pursue a tellowship
arrangement Perl helped organize w ith s|-)inal
cord phy siologist Motoy Kuno. Kuno. who
had been recruited by Perl w hen he became
department chaimian. was particularly inter-
ested in the interactions between the motor
neurons in the spinal cord that inner\ale
muscle cells. Sniderexplained.
"He formulated ideas about trophic' in-
teractions, trophic' having to do with nour-
ishment, in that the muscle nourished the
innervating neuron." he said. ",\t the linie we
had no idea about the molecules in\ol\ed in
this. So I guess I became fascinated w ith
those questions, and my subsequent career
has largely been de\t)tcd to study ing the mol-
ecules that mediate these trophic interactions
in the nerxous sy stem."
■After graduation in 1 977. Snider elected to
continue clinical training and interned at the
Har\ard-affiliated Beth Israel Hospital in
Boston. He then completed a residency in
neurology at Cornell, at the time considered
the premier neurology training program in
the nation. While at Cornell, he met his wile.
Barbara, w ho was completing her psychiatric
training at Paine- Whitney. She is board-certi-
fied in child ps\ chiatry.
As it turned out. Snider eventually was
able to combine both science and clinical
work. He accepted a post-doctoral fellow-
ship at Washington University and subse-
quently joined the neurology faculty.
"My clinical interest was neuromuscular
disease, including amyotrophic lateral scle-
rosis (commonly referred to as Lou Gehrig"s
disease or ALS), peripheral neuropathies and
pain."" he said. ""I was able to tie together w hat
1 worked on in the laboratory and observed in
clinic patients."
But Snider allowed that after Id years in
St. Louis, he had "reached the stage in my ca-
reer when the opportunity to develop and
lead something sounded very appealing.""
Word that his old alma mater was setting
up a neuroscience center, a research center
that wt)uld cross various disciplines at the
medical school, and that there would be a
substantial tlnancial commitment for faculty
space in a new building seemed to Snider the
perfect challenge. A return to Chapel Hill
also seemed a sweet symmetry.
Snider"s goals for the center arc ambitious.
In his temporary office at the UNC Lineberg-
er Comprehensive Cancer Center, he be-
comes more animated when he eagerlv
outlines them. One can readily sense his pas-
sion for the work.
"1 would like to combine a couple of
themes in basic and clinical neuroscience
that will be very inlluential in the 21st centu-
ry."' he said. "The first of these is develop-
mental neurobiology, aiul mv tlrsi mission
v\ ill he lo slienglhen and evpaiul the tlevelop-
ment of that area on campus here.
"t)ur ability to understand how the brain
tonus, how particular types of nerve eel Is dif-
ferentiate and send axons to the appropriate
regii)ns of the brain and not to other regions,
how synapses fomi and lunction - molecular
genetics has opened up this field in w ay s that
could not hav e been imagined a decade ago.
".And so I plan to make brain development
the first area of effort for the Neuroscience
Reseiu"ch Center."" he said. "This will primar-
ily involve people working on mouse mod-
els, using the genetics ot the mouse to
understand the genetic basis for how the
brain dev elops.
".A second goal, perhaps one that w ill
make the center unique, is to combine issues
in developmental neurobiology and research
related to clinical neurology,"" he added. ""We
would focus panicularly on issues related to
repair of the nervous system, repair of dam-
age after spinal cord injuries and after stroke.
It is almost certain that the same things that
govern neural development will be important
for nervous system repair."'Snider noted that
the center itself will not go into treatment at
the level of clinical trials.
"Wc arc interested in the science lounda-
tions of therapy related to brain and spinal re-
pair, and so we would be try ing ti) recruit
people who would be studying the surv ival
of nerve cells, differentiation of nerve cells.
gR)w th of axons of nerve cells, and we would
also be interested in recruiting people who
are attempting to repair the nervous sy stem
after injuries,"" he said. "This is working
beautilully in mouse models now.""
But Snider is not averse to peering into ihe
future forclinical applications.
"The great progress in isolating human
embryonic stem cells means that we might
potentially apply the know letlgc of develop-
mental processes to the successful repair
of nervous system injuries m |ieople,"'
he saul.
Alinniii Profile
Dr. Daniel E. Brown: Pc:
By KathtTiiu' Kopp
When Daniel E. Brow n giadii-
aled from the UNC School ol
Medicine in 1965. he didnl
begin lo know how far — lit-
eralK — he w ould go in his career.
Though most of his work as a pediatri-
cian has taken place in Raleigh. Brow n last
vear spent Iwo-and-a-half months half a
world away serving on a medical mission
team in .Africa.
He said it is no exaggeration to sa\ the
experience changed his life.
This year. Brown celebrates his 3.5th re-
union year. His career path is familiar to
many physicians; After graduating, he com-
pleted an internship and residenc\ in pedi-
atrics at Shands Hospital, now part of the
University of Florida-Gainesville hospital
svstem. including a year as chief resident.
Then he entered the U.S. An Force.
■'Back then, we had what was called the
Berrv Program." he recalled. "If you en-
tered this program, you had a commitment
to mililai7 service for a period of time."
So after completing his medical training.
Brown and his wife. Barb;ua. a graduate of
the UNC School of Nursing, spent two
\ ears at March Air Force Base near River-
side. Calif
In 1470. Brown, a natne of Selma in
Johnston Coiintv. retiimed to North Caixili-
na and |oined the Raleigh pediatric practice
of Frank Winslow and Frank Poole, two
well-respected North Carolina pediatri-
cians. The practice is now known as Blue
Ridge Pediatrics: Brown is one of five pedi-
atricians in partnership there.
Brown credits his mentors with helping
hmi refine his skills as a pediatrician in his
earl\ \ears of practice. He also learned a lot
from the e\ents of his own life. When he
and Barbara mo\ed lo Raleigh in 1970. the\
w ere the proud parents of three young
daughters. Deborah. Jennifer and Virginia.
Like most pediatricians. Brown acknowl-
edged that becoming a parent himself
tautihl him more about carini: for children -
Daniel Brown. '65 and one of his patients are all smiles on his reeent trip to Kenya.
and their parents — than textbooks and lec-
tures ever could.
"Once you ha\e your ow n children. \ou
really begin to understand sour patients and
their families." he said.
In 1976. the Browns welcomed a fourth
child into their faniih. Daniel E. Brow n Jr.
The follow ing v ear. young Dannv died from
a metabolic illness.
"That event changed our li\es." Bmw n
said simply. "It changed our lives, and it
taught me a lot."
In manv wavs. the famih 's tragic loss
represented a turning point for Brow n. both
personalK and professionally.
".After our son died. I felt I had so much
more empath\ for families who were going
ihrough difficulties." he said. "Whenever I
had contact w ith a famih w ith a seriously ill
child or a family w ho lost a child. I could re-
allv empathize with what they were going
through. And in a lot of ways, losing our son
tested my faith, but it also made it stronger."
Brown, a devout Christian and a member
of Pro\ idence Baptist Church in Raleigh, is
unafraid to profess his beliefs. .And through
liatrician with a Mission
the years he has put his faith into action, most
recently doing medical mission work. In
1994. he joined a medical mission team
sponsored hy Baptist World Relief.
"Our team tra\eled to Zaire for three
w eeks to care for children orphaned by the
ci\ il w ar in Ru anda." he said. "Though I \\ as
only there for a feu weeks, the experience
had a major impact on me. It piqued in\ in-
terest in mission \\ ork."
In 199.>. Brown attended a conference in
Asheville calleti "Prescription for Renewal."
sponsored h\ .Samaritan's Purse, a relief iir-
ganization headed by Franklin Graham.
"Samaritan's Purse has an arm called
World Medical Mission." explained Brow n.
"They send \olunteers all over the world to
pro\ ide medical care and assistance."
After attending the conference. Brow n
was detemiined to take another mission trip.
After some research, he set his sights on
going to Tenwek Hospital near the tow n of
Bomet in a remote part of western Kenya.
The logistics of taking extended lime off
from private practice were challenging.
"It took almost three \ears to get e\er\ -
thing in place so I could be gone for two-and-
a-half months." Brown said. "It takes a lot of
effort and cooperation from your partners to
work out something like this. It's hard to be
out of the office tor such a long period of
tunc."
Brow n's w ife and their s oungcst daughter.
a teacher, accompanied him to Keny a.
.As might be expected, practicing pedi-
alncsin Kcn\a is light \ears awa_\ from prac-
ticing in Raleigh.
"In pediatrics today, you still see a lot of
acute illness, but pediatrics has detlnitel>
changed over the years." Brown said. "Now
in private practice, we spend a lot more time
working through situations like attention
deficit disorder and psychological and hc-
ha\ ioral problems. These kinds of issues take
up much more time than in the past.
"The was pediatrics is practiced has
changed as well." Brown continued. "We
used to just pick up the phone and call w hen a
child needed to sec a specialist like a neurol-
ogist or a surgeon or a gastroenterologisl.
Now we have to look at the list from the pa-
tient's insurance company, which may or
may not have the name of the physician
\ ou'd like to refer to on it. and go from there.
There's a lot more bureaucracy and paper-
work than there used to be."
In cimtrasi. Brow n discovered that practic-
ing pediatrics at Tenwek meant treating one
acLite. often life-threatening, illness after an-
other. .And as far as making refeiTals to spe-
cialists'
"There's not much access to specialtv care
in western Kenva." said Brown. "Nairobi is
more than an hour aw ay by plane and four-
and-a-half hours by car. and transport to the
citv is often not available. At Tenwek. there
are about six staff physicians for 300 beds.
The rest of the doctors there are part of a
changing group of volunteers."
Many of the children Brow n treated in
Kenya were seriously ill.
"The biggest problems there were menin-
gitis, pneumonia and TB." he said. "These
were often associated w iih AIDS, w hich is
very common in both mothers and children
in Africa. We also were dealing with tremen-
dous problems w ith malnutrition and dehy-
dration. It's so different from the U.S. Here.
if vou're sick, it's just a short ride to the hos-
pital or the doctor's office. There, we serv ed
a .^OO-square mile area. Patients got to the
hospital on foot, by mule and occasionallv.
bv a motored vehicle. There are no ambu-
lances. Most of the conditions we saw were
treatable, but for a lot of patients, it's a two-
dav trip to get to the hospital. These kills
were really sick by the time they got to us;
thev were often in critical condition. Some ol
them came in too sick to save. The first two
w eeks I u as there, we had 1 2 children die.
■We had 45-60 kids in the hospital at a
time." Brown added. "There was a severe
epidemic of malaria while we were there. ,At
times, we had two or three kids to a beil. The
ones we were able to save generallv did well,
without complications. '"I'ou do see a lot of
children ilie. and that's hard. But there aren't
resiiLMces there to care for kids \\ ho surv ive
but need continuing medical treatment. That
care is just not readilv available. .As one nns-
sion nurse said to me. 'There are worse
things than dying in Africa.'"
Despite the hard work and many chal-
lenges. Brown refused to get discouraged
during his siav in Kenv a. Instead, he focused
on the progress Tenwek Hospital made to-
w aid improv ing medical care for the region.
"The hospital just graduated its first class
of nursing students." he said. "One hundred
percent of the class of 2.^ to M) passed the
Kenv an nursing boards."
Brow n took great pride in mentiiring a
young African physician in the hospital's
new internship and residency program.
"There are just two medical schools in all
of Kenya." explained Brown. "In Kenya, stu-
dents take their boards right after graduation,
then usually do a one-year internship before
going to work. There aren't many residencv
programs in the country, and there are more
graduates than there are spaces. Tenwek just
began this new internship and residencv pro-
gram, and I was verv luckv thai mv time
there overlapped almost directly w ith .Agnes
Langat. a young intern doing her pediatric
training. She was spending a vear rotating
through medicine, pediatrics. OB-Ci'*i'N
and surgery, and il was verv exciting to be
able to work w ith her. During mv time there.
I was also able to help the hos|iiial tlevelop
a curriculum for pediatrics. It was verv
rewarding "
.All in all. Brov\n's iime at rcnwck Hospi-
tal was an experience he lio|ies to repeal in
another vear or two
"I am sii much moie .ippiecialivc now ol
all that we have in icrms nf icsoinvcs in this
countiv." he said. "Our mcilic.il cue. ihe
availabililv ol Iraiispoilalion. coiiimunica-
tion sv stems n's so ililfeiciil in .Africa.
But It was verv ins|iiriiig to me to see |Vo|ile
of various faiths anil denominations. Iidiii
all kinils of meilical backgrounds, coming
together to help enrich ihis part ol the
world. I'hcie is sd iiuicli oppnriiiiniv iheie u>
help others."
UNC Surgeons Perform State '^l
■Domino " liver donor Jim Hiiiilvr I U'fl). unj rccipicnl Gtirx Bo^ciri;c' cli\ciiysvs ihcir ni.sc with reporters.
By Karen Stinneford
UNC surgeons performed a rare
"'domino"" liver transplant opera-
lion in March when they put a ca-
daN'cric liver in one recipient and
then transplanted that recipient's tlawed-hut-
lunctionul li\ er into someone else.
The no\el transplant technicjue — never
before done in North Carolina — has oc-
curred only about 30 times worldw ide since
first performed in Miami in 1996. UNC sur-
geons said the ■'domino"" approach likely will
become routine as doctors continue to seek
new ways to address the critical shortage ot
a\ ailable cadaveric organs.
"This represents the ultimate in recycling
— gi\ ing a person who desperately needs a
liver one that otherwise would have been
thrown away."" said Jeffrey Fair. MD. chief of
10
the abdominal transplant program at LINC.
"As long as there are more patients who
need organs than there are organs available,
medicine will have to find new ways to help
people with no other options."" he said. "Ap-
proaches like a 'domino transplant' w ill ha\e
to become more commonplace."'
P. James "Jim"' Hunter. 5S. of Pinehursl.
was the first person to recei\ e a new liver dur-
ing the procedure. Hunter suffered from
amyloidosis, a rare and ultimately fatal dis-
ease in which his liver produced a variant
protein — called amyloid — that his body
could not process.
Because it wasn"t used or eliminated, the
protein collected in cells throughout Hunter's
body, damaging his central nervous system
and heart. He underwent a heart transplanl at
UNC in June 1998 and also was placed on a
w aiting list for a liver transplant, which repre-
sented the only "cure" for amyloidosis.
The rationale behind using a liver from a
patient w ith amyloidosis is that the disease
progresses quite slowly, said Mark Johnson.
MD. director of the renal transplant program
at UNC. Build-up of the abnormal protein
won't become clinicall_v significant for some
10 to 15 years, he said, and it will take anoth-
er 1 5 to 20 years before permanent damage
results from that build-up.
"So the functional life span provided by
one of these transplanted livers easily can be
2.5 to 35 years." Johnson said.
So on March I . Hunter receiv ed a normal
liver from a cadaveric donor. But rather than
dispose of Hunter's liver — which is the
noim follow ing such an operation — doctors
liansplanted it into 49-year-old Gary Bosarge
ofRichlands.
Whv w ould Bosarge w ant a defective liver
^irst 'Domino' Liver Transplant
Transplant suri;eons Mark Jiilinsiiii. MD. llcfn ami Jcffercx Fair Mi), hclicvc ilmior iransphuiis will help paiunis in need.
know n to produce a poicntiall\ litc-threatcn-
ing protein .' His doctors said it is because
Bosarge's own health problems posed a more
immediate threat to his lil'e.
Bosarge sutlers from hepatitis C. a chronic
mlection that lrequenil> results in pennaneni
scarring — or cirrhosis — of the li\er.
Bosarge was infected with the hepatitis C
\ irus in 1979 when he recei\ed a blood trans-
lusion after a helicopter crash in South
America, and his liver had become so scarred
it no longer worked adequately. As a result.
Bosarge experienced tremendous pain,
weakness and bloating and was almost to the
point of being unable to v\ork.
"He was in bad shape — sick as a dog."
said Roshan Shrestha. MD. medical director
of the liver transplant program at INC. "He
said that e\er> da\ he could feel himself
going a little more downhill."
So I'.NC" physicians offered him Hunter's
li\er — along with a long laundr\ list of
problems that might follow if the transplant
took place. Shrestha said that his patient, who
has a 1 ."^-year-old daughter, leapt at the op-
piiilunity. figuring an_\ li\er had to work bet-
ter than the one he had.
"He told me. "If I can live 20 iiune \eais.
I can see my daughter get married."
Shrestha said.
Waiting for a completely healthy li\er
posed problems, too. Johnson said. Gi\'en the
huge demand for cadaveric organs. Bosarge
likel) faced spending another year on the
waiting list before one would become avail-
able. By then, his health could have deterio-
rated to where he was no longer a suitable
candidate for transplant surgery.
"There are. admitiedlv. a lot of uiiknow ns
here." Johnson said. "But given what we
know about amyloidosis and the time it takes
for the disease to manifest itself, we think Vlr.
Bosarge could have 20 to .^0 years of good
health before his new liver starts causing
problems. And by then, medicine certainly
will have discovered a more effective treat-
ment than what we can offer now "
Fair agreed, adding. "We could have
thrown the liver away, but it had the poicniial
to help someone. And whenever \ou can help
someone, vou should."
Hunter and Bosarge both left L'NC Hospi-
tals about eight days after their surgeries.
Since its^start in 1991. UNC Hospitals-
liver transplant program has grown into one
of the largest and most successful in the
Southeast. Among the program's main
"firsts" was that doctors here performed the
slate's first living-related liver traiis|ilani m
194(1.
Some 14.724 people in the liniled States
currentiv aic awaiting a liver transplant,
accortling to the I'nited Network for
Organ Sharing. In I9MS. the latest year avail-
able, about I ..^00 palieiils died before thev
could gel a new liver. Last year. 4..'i()0
liver transplants were |XMfoniied in the Unii
ed States. D
UNC Health Care Acquires
Raleigh's Rex Healthcare
Nearly one year follow, ing UNC
Health Care's announeed interest
in aeqiiiring Rex Healtheare in
Raleigh, the deal was done. Chief
Kxeeuliv e Offieer Jeffrey L. Houpt. MD. and
Rex Healtheare Trustees Chairman James B.
Hyler Jr. announced in mid-.April that Rex
Healthcare is now part of the UNC Health
Care System.
"The new relationship w ill complement
and expand the existing ser\ ices and pro-
grams offered hy Rex and UNC, and enhance
the abilities of holh organizations to ser\e pa-
tients and families in the greater Triangle
area," Houpt said.
Hyler agreed, adding, "residents of Wake
County will continue to receive the same
high-quality health care Rex has provided for
more than 100 years, with the added benefit
of new programs made possible by L'NC
capital."
Hyler said Rex will in\est in additional re-
sources to better ser\ e the health-care needs
of a grow ing Wake County and Triangle area
population.
"Through our affiliation w ith UNC. Rex
also w ill gain greater access to high-le\el
clinical programs, advanced technology and
medical research," he said.
Under the agreement. Rex Healthcare w ill
continue to operate as a separate, private, not-
for-profit entity and will retain its separate
identity. Its employees will remain employ-
ees of Rex Healthcare.
I'NC and Rex anticipate both growth and
expansion of ser\ ices and cost-sa\ ings under
the agreement.
Governing Boards Reorganize
The agreement making Rex Healthcare
part of the UNC Health Care System result-
ed in changes to both organizations" go\'-
erning boards and appointments of
directors for the new ly established John
Rex Endowment Board.
The new Rex Healthcare Board includes
the following current Rex board members:
William C. Burkhardt, Jean W. Carter, MD.
James T. Fain III. Charles T. Francis, Ann
Goodnight, James B. Hyler Jr., Robert A.
Ingram, Richard S. Myers. MD, and Waltye
Rasulala, UNC"s appointees to the
Rex Healthcare Board are: J. Slade
Crumpton. Eric B. Munson and Thomas E.
Sibert. MD.
The UNC Health Care Board includes
the following current UNC board mem-
bers; Molly Corbetl Broad. J. Slade
Crumpton. F-rank .A. Daniels Jr.. M.
Andrew Greganti. MD. Jeffrey L. Houpt.
MD, John A. Kirkland, MD, Estell C. Lee.
William McCoy, R. Malloy McKeithen.
Eric B. Munson, Valerie Parisi, MD. Bailey
Patrick Jr., Paul J. Rizzo, William L. Roper.
MD. Charles M. Shelton and John S
Ste\ens. Joining the Board from Rex are:
Jean W. Carter, MD, Richard L. Daugherty
and James B. Hyler Jr.
The governing board of the new John
Rex Endow ment. chartered to ad\ance
health care in the greater Triangle area, will
consist of 12 members. Named to serxe at
the tiine of this printing were: David
Boerner, MD, Ben L. Bradsher, William C.
Burkhardt, James T. Fain III. Charles T.
Francis. ,\nn B. Goodnight, James H. May-
nard and Waltye Rasulala. UNC"s represen-
tati\es are Jeffrey L. Houpt, MD. William
McCoN and William L. Roper. MD.
The transaction. \ allied at S2yo million,
calls for establishing a new John Rex Endow-
ment and funding a number of Joint UNC-
Rex projects. Financial details of the deal
include:
• SI 00 million to go toward the new John
Rex Endowment. Twenty-f"i\e million of this
will be returned to Rex Healthcare for capital
projects. Income from the remaining
S7.S million will be used to support indigent
care and enhance communit\ health-care
programs in the greater Triangle area.
• S?X million to be committed by UNC to
fund strategic initiatives jointly agreed upon
by Rex and UNC. These could include ex-
panding cancer care, pediatric ser\ices and
women's serxices.
• SI 32 iTiillion in existing long-term
debt to stay w ith Rex Healthcare and its affil-
iates. These liabilities remain on the Rex bal-
ance sheet. D
and Rex Healthcare
Combined Service Area
Four County
Pnmar; Care
V
G R A N V I L
ALAMANCE
ORANGE
DURHAM
WAKE
I.l
CHAPEL
■ HILL
P'actri-t Pijtuer/ _ Hoscitals
CHATHAM
Carolina Dialysis
VANCE
FRANKLIN
Blue Ridge Family Pra
Rex Primary Care
of North Raleigh ^ , ^
\ Future Sile of '" '
Rex Healthcare ' WAKE
of Wakefield FOREST
X \ ,^ Wake Forest
-\" „ , , ,\ V Pediatncs
Boylan Internal
Rex HorVie Medicine
- _ . Health — -
.lid-Caroliria"" - \_ \ ""• Rex Hospital & 1
Homecare • vm) ^Ns. x Rex Wellness
Special'^'* r,: ~^\. >^ Cenle
Rex Obstetrics
Cnainarr J Gynecology
^^°"'"9 NC Kids of Raleigh
/.
RALEIGH
^
Rex Healthcare of Cary
Rex Family Practice of Cary
Rex Pediatrics of Cary
Rex Urgent Care of Cary nauFo
Rex Wellness Center of Cary """"'='' 7o
CLAYTON JOHNSTON
Sarifo'r; Scecifli
Clinics
\ Game'
\ Prac
Farr.ily
Practice
Match Day 2000:
Match Day. That annual event when
medical school seniors nationwide learn
which residency program they will enter.
This year's event was held on March 16
and approximately 140 graduating UNC
medical students filled the Clinic Audito-
rium.
"As a group, our students arc incredibly
accomplished and talented people, and
Match Day is just one more manifestation
of their achievements," said Georgette
Dent, MD, associate dean for student
affairs.
"Traditionally, our students have done
very well with regard to getting good resi-
dencies; last year, the percentage of our
students who got their top choice was
higher than the national average," she
added. "That says UNC is doing a great
job educating these students, and as a re-
sult, they are considered excellent recruits
by other programs."
About 86 percent of UNC medical stu-
dents were matched with one of their top
three choices during the computerized
process. Sixty-four percent received their
first choice.
John Yiuini; (rli^hij. xluircs his lellcr with friends.
2000 Residency Target Placements
Specialty Placements
Johnailian Bradley Woods Is all smiles on Mateh Daw
14
Family Practice
■■^^^
^^m ">
Inicrnal Medicine
2*
Medicine-Pedialncs
■■■ -f
Obsietrics/Gynccolog)'
8
Pediatrics
^^^^^^
^^^^^^
Anesthesiology
■ 7
Dermatology
■i 2
Emergency Medicine
8
Neurological Surgery
>, Neurology
■ l
1
-^ Orlhopcdit Surger>'
■ 7
,^ Otolaryngolog>'
% PM&R
H Patholog)'
Plastic Surg- Preliminary
Plastic Surgery
^^ 3
1
■ 1
1
Psychiatry
Radiolog\ -Diagnostic
Radio logy -Oncologic
Surgery-General
Surgery-Preliminary
Urology
Deferred
hi II
6
0 3
10
Numf
15 20
cr of Seniors
25
'The World Is Your Oyster'
By Lynn W'ooten
The world is your iiNster.
So it is. pertiaps. fitting that as the>
prepare to head off on their own
into their chosen professional
world. UNC medical students recei\e a
feu pearls.
Pearls of w isdom. that is.
Continuing a long and much-anticipated
tradition. School of Medicine facult\' of-
fered helpful hints, special reminders and
often-touching ad\ ice to students at the an-
nual Pearls Day gathering.
Through skits, slide shows and simple
heart-to-heart orations, faculty ga\e stu-
dents a feu things to think about as the\ set
out to become physicians theinseK es. Their
"pearls" ranged from the serious to hysteri-
cal, but no matter what the message, each
facultN member received heart\. apprecia-
tive rounds of applause from their soon-to-
be fonner students.
■Among the "pearls" offered for consider-
ation uere:
Georgette Dent, MD. associate dean tor
student affairs — L'sing special lighting ef-
fects (uell. OK. flashlights ua\ed from the
front rou ) and slides. Dent created her own
riotous \ersion of the megahit TV game
shou. "Who Wants to Be a Millionaire'.'"'
But her game. "Who Wants to Be Board
Certified'"" offered such mind-numbing
questions as "Paroxysmal nocturnal hemo-
globinuria is lypicall\ characteri/ed b\ an
abnormalitN in which of the l'olKn\ ing'.'""
For assistance, contestant/ student Donald
McLamb elected to "call a friend"" —
Stephen Kiser. MD. professor and associate
chair for medical education.
John Thorp, MD. associate professor of
maternal-fetal medicine — Thiirp focused
on the importance of physicians making
strong connections u ith their patients. "Sit
dou n u hen \ ou talk to patients."" he said. "It
gi\es the appearance of concern."
.\nthony Meyer. MD. professor and di-
\ ision chief general surgery — No matter
u hat is going on in a physician"s life. Meyer
pointed out. the doctor should not be
distracted or negatively effected to the detri-
ment of interacting uith patients. In other
words, personal baggage should be leli out-
side the door. "In patient caiv. the person in
the forefront of \(iur mind shinild be the pa-
tient, not \ourselt "
Anthony Lindsey. MD. clinical associ-
ate professor of general ps\ chialr\ and be-
ha\ ioral medicine — L'sing photographs of
de\oted UNC employees as his backdrop.
Lindsey stressed the importance ot assis-
tants, nurses and other support personnel in
a physician"s life. He suggested that the stu-
dents, once the) are on their ou n. alua\ s
remember — and appreciate — u hat these
people ha\'e to offer.
Harvey Hanirick, MD. professor of
communit\ pediatrics — Hamrick noted
one of the greatest fears a physician has:
Becoming the target of a malpractice
lausuit. With apologies to Da\ id
Letterman. he offered up the Top 10 Rea-
sons to .Axoid a Malpractice Suit ("Worst
of all. your family uill encourage
you to go to law school."") and the Top 10
Reasons You Might Get Sued l"^'ou"\e
never been sued."") D
2000 Residency Target Placements
Primary Care Placements
^
^r^
^^r^
m
l^yp
1 ^^^1
I'dlrii III ( (ij'jHi'^i I It In. iiihl lliiillu I Rdhi ilsoii Wliilv tii/(n </ //>,■/(/ iiuniit iil on
SUiuliDax.
AHEC: Taking Medicine tc
Naiuy Pfifcr. Ml), ciiul tliinl-ycar resident lllvti Wilkcrsaii review seheJule.s.
To understand the partnership be-
tween the UNC School of Medi-
cine and the N.C. Area Health
Education Centers (AHEC) Pro-
gram, you really need to leave Chapel Hill.
You might head to Asheville to the Moun-
tain AHEC, or to Wilmington to the Coastal
AHEC. You could travel to the Southern Re-
gional AHEC in Fayettc\ ille, to the Charlotte
AHEC. or to Wake AHEC in Raleigh. Head
west out of Chapel Hill and the tlrsl AHEC
you'll pass is in Greensboro.
The AHEC Program and the School of
Medicine share a mission to meet the health
care needs of the people of North Carolina.
Greensboro AHEC. like the other sites, pro-
\ ides the School with the resources to offer
community-based training to medical stu-
dents and residents and to provide profes-
sional support and continuing medical edu-
cation for physicians in the communities
where they practice.
Greensboro AHEC offers residenc\ place-
ments in family medicine, pediatrics and
internal medicine. The residency programs
are sponsored by Moses Cone Healthcare
Svsieni in conjunction with the L'NC School
of Medicine.
The program in internal medicine accepts
20 residents and provides opportunities to
learn in an environment that emphasizes the
generalist skills necessary to enter a commu-
nity-based practices. Residents function as
primary-care physicians w ho deliver conti-
nuity care for both inpatients and outpatients.
Residency faculty members pio\ ide this edu-
cation with e\tcnsi\e support from commu-
nity preceptors
The AHEC Program addresses the short-
age and maldistribution of health-care pro-
fessionals in underser\ed regions and
encourages students to practice in those areas
bv allow ing them to train alongside mral and
communilN practitioners. AHEC also pro-
vides informaliim resources and prolessional
support that rural physicians need to stay on
the culling edge of medicine. Since the N.C.
AHEC Program began, nearly ."i.^S family
doctors trained in AHEC-based residency
programs ha\e settled in communities across
North Carolina.
"The moie students we tram in communi-
tv-based settings and the more we support
existing rural practices, the more attractive
and better those practices become."
said Thomas Bacon, DrPH, Director of the
N.C. AHEC Proeram and Executive
s[orth Carolina's Communities
Associate Dean.
The AHEC projiram began in 1972. It was
one > ear later that Stew art Rogers. MD. grad-
uated fnini the School. Rogers, a tenured lac-
ult\ member at L'NC. has v\orked in internal
medicine through Greensboro AHEC for 2 1
years. Rogers belie\es one way AHEC im-
proves health care in communities is by cre-
ating an academic presence in the slate's
hospitals.
'AHEC bnngs t'acults and their talents as
resources." he said. "The presence of medical
student training programs and residencs pro-
grams like we ha\e here in Greensboro gi\e
practicing ph\sicians the opportunity to
teach and sta\ connected w ith schools of
medicine."
Rogers places great \alue on his ov\ n com-
munity-based rotation as a medical student.
"\h familN is from Greensboro, and I was
excited to he an acting intern in pediatrics at
Moses Cone. I enjoNed it a great deal." he re-
called. "I especially appreciated the indepen-
dence ol doing meaningful clinical work
awa\ from the uni\ersity."
.\anc\ Pilfer. MD. 'S7. also is a full-tmie
laculty member for the internal medicine res-
idency program in Greensboro. A nati\e of
Morganton. she completed three community
rotations as a student. And like Rogers. Pfifer
valued the hands-on nature of the rotation
"I lo\ed it. mostly for the one-on-one ex-
perience with the attending." she said. "I re-
member once during my OB rotation at Wake
AHEC. I got to do nine deliveries in one
night. My peers back on campus didn't gel
any w here near that kind of exposure. "
illy a Wilkerson is a third-year resident in
Greensboro's internal medicine program and
has trained w iih both Rogers and Pfifer. A na-
tive of Eden, he graduated in IW7 and rates
his experiences w ith AHEC as "wonderful.
My community rotations and residency pro-
vided me with practical experiences where
the attending phvsicians were verv approach-
able and students were a prioritv."
Besides his rcsidencv. V\ ilkcrsdii complet-
ed a family practice rotation at Southern Re-
gional AHE:C and an OB and emergencv
medicine rotations at Wake AHI.C. and com-
pleted thml-vear medicine inpatient and (uil
patient rotations and a lourth-vear acting in-
ternship at Greensboro AHIX" laniilv \Iedi-
eine Clinic.
Wilkerson plans to practice medicine in
the Greensboro region. He plans to rely on
AHEC for resources necessary for this new
phase of his medical career.
"I haven't felt any disadvantage working
in Ihe communitv and a distance from Ihe
School." he said. "I can relv on AHEC librarv
resources during the ilay or night. .As long as
I'm in the stale. I'll take advantage of all ihe
serv ices AHl:C prov ides."
Those resources are one ol the reasons the
AHEC ProL-ram is so suecesslul. Ko.jcrs
said.
"It's easy uiulei ihe pressures ol private
practice for phvsicians lo lose louch w ith the
education process. " he said. "I think manv
private physicians are grateful for ihe first
class library resources, continuing education
programs, off-campus degree programs for
mid-level health-care professionals and the
many other resources .AlliX" brings to the
communitv "
Besides piovulmg prolession.il support,
the School ol Mi-dkineaiul Alll.Caic iin
poilanl partners in palieiil education as well.
Wilkerson said.
"Ediiealing the palienl is a big part of the
battle in improving healtlicare outcomes." he
said. "With access to .AHEC libraries and
their online resources, information from
teitiai V research centers comes into commu-
nities m verv expeditious fashion. .AHEC
improves health care bv iinprov ing access to
practitioneis. bin also bv providing
educational programs loi prolessionaK and
their palienis." D
Kids at UNC Hosp
To Talk With O
Allwdii Sillier nt Rccivcitiaiuil Therapy liclps n puiicni upcniic STARBRICjHT.
By Melissa Matson
Imagine thai you're 1 2 years old and
have cancer. Trips to the hospital lor
chemotherapy are wearing you out.
You're in pain and afraid of what \s ill
happen to yi>u. On top of that, you feel like
Nou're the only one in the world going
through this.
Now imagine sitting at a computer and
talking face-lo-face with a 12-year-old can-
cer patient in another state. He tells you he"s
going through chemotherapy too. and like
vou. is really sick. He"s also scared that he
won't get well. '\'ou'\e found a friend.
Children at UNC Hospitals are doing that
through STARBRIGHT World, a prixate. in-
teracti\ e computer network for hospitalized
18
children. The brainchild of film producer and
director Steven Spielberg. STARBRIGHT
World began in \^n5. Spielberg's idea was to
enable sick kids to interact \ia \ ideoconfer-
ence with other children facing similar health
challenges.
•■We have created a true \ irtual pla> ground
— a place that can help children recapture
the joy of being a kid. Regardless of how far
technology ad\ ances. it is the human connec-
tion that matters." said Spielberg, chairman
of the STARBRIGHT Foundation.
Last summer. UNC Hospitals became the
first hospital in the Southeast to join the net-
work. The day was celebrated w ith much
fanfare, including a \ isit from the late
N.\SCAR driver Adam Petty, who donated
iiKinev to the project.
Since then. STARBRIGHT World has re-
ceived ra\e re\ iew s from UNC's pediatric
patients.
"The kids love this." said Allyson Salier. a
recreational therapv assistant in charge ot
UNC Hospitals' STARBRIGHT World.
"The first thing the\ do when they come for
return hospital visits is ask me when they can
siet on STARBRIGHT."
Currenth. UNC Hospitals has five STAR-
BRIGHT World temiinals — one in its pedi-
atric plavroom. I'ne in the N.C. Javcees Bum
Center, one in the Hospital School, one in its
pediatric hematologv/oncologv unit and one
in the bone marrow transplant unit.
■When the new N.C. Children's Hospital
opens, we hope to have additional comput-
ers." said Salier. "We plan to w ire every inpa-
als Use Computers
ler Sick Children
Sprint teams with the
STARBRIGHT Foundation
These duN s. many busi-
nesses look beyond profit
margins to how they can
participate in and
strengthen the communi-
ties around them. Spnnt is
just such a company.
So when the STAR-
BRIGHT Foundation
went looking for a
telecommunications com-
pan\ to help create STAR-
BRIGHT World. Sprint
stepped up to the plate.
Now. Sprint is STAR-
BRIGHT World's exclu-
si\e telecommunications
pro\ider.
That means that Sprint
donates the multi-million
dollar network infrastruc-
ture that enables thou-
sands ot children to
simultaneously e-mail
each other: to see and
speak w ith their peers any-
where on the network
through \ ideoconferenc-
ing; to play together in
real-time through interac-
t:\c computer games; and
to understand more about
their illnesses through
multi-media educational
programs.
The technology, called
.As\ nchront)us Transfer
Mode (ATM ) network,
makes fast, secure data
transmission possible.
The result is that 100 hos-
pitals can simultaneously
send and receixe data,
voice. \ ideo and sophisti-
cated programming.
Sprint is a global com-
munications companv
working to integrate long
distance, local and wire-
less communications ser-
\ices. Sprint built and
operates the United
States" first nationwide
all-digital, fiber optic net-
work and is a leader in ad-
\anced data communi-
cations services and is
a leader in advancctl
data communications scr-
\ices. Sprint has SI7 bil-
lion in revenues and
serves more than 17 mil-
lion business and residen-
tial customers.
patients.
r\ jhiiudiir Willi pcduilrii.
lient r.Kim lor STAKBKIGHT World.'
Besides its \ ideoconference capabilities.
STARBRIGHT World offers video games
and Internet access to 4(K) pre-approved Web
sites. Children can find infomiation on a va-
riety of illnesses, tests and treatments, or ihev
can forget health issues altogether and play a
game for fun.
VV'hen Salier sits dovMi with a peiliatric pa-
tient at a STARBRIGHT World computer,
she's neverquite sure what will happen.
"I let the kills go where they want and do
what thev want wilh STARBRIGHT," said
Salici. "It's important for them to feci that for
a short lime during their dav. thev have some
control.""
Through .STARBRIGHT World, kids can
also post questions like "What's ihe worst
part of chemotherapv .' " on a medical
bulletin board. Or they can search lo see w lio
IS online.
"I was with one 17-v ear-old who luul |usi
been diagnosed with cancer. " said Salier.
"When he sat down, the tlrsi thing he did was
look up his tvpe of cancer. Then he ran a
search lo tiiul sonieoiic aroiiiul his .rje who
had alreadv lost their hair.""
Rveryone involved with .STARBRIGHT
World at IJNC Hospitals — from the doctors
to the recreational therapists to the patients
themselves — have come awav praising
the sv sieiii,
■Ourevpcrience is ihat STARBRIGHT
World allev iates some of the an.xiely and fear
children feel in the hospital."" said Harvey
Hamrick. Ml), professor of pediatries.
"We are so |ilcasetl lo be able to offer it to
oui palieiils." n
19
Faculty Profile
Harvey Hamrick, MD:
Hiinc\ Ihiiinick cxcuuinvs Jciiiufvi- Rnullcx. 7. aj Snow Ciiiiip. NC
K\ Lviin W'ooten
As one (it L'NC's best-known and
icspected pediatricians. Harvey
Hamrick, MD. obviously has a
way with children. As it turns out.
he has a way with words, as well.
"One of the things that stands out about
Di-. Hamrick IV>r the residents and students
training w iih him is his speech mannerisms.""
says Alan D. Stiles. MD. acting chair ofthe
department of pediatrics. "He frequently in-
corporates "sayings" in his teachings that I
am sure date from his childhood in western
North Carolina. Forexample. he"ll say some-
thing like. 'It looks like the chickens have
come home to roost." when a diagnosis has
been closed in on. One of our past residents
assembled many of these to share at a depart-
mental 'jaiheriniz. Evervone there could re-
member situations where these were used.""
In fact. Hamrick has left such a big im-
pression on many of his colleagues, patients
and friends throughout his years at UNC that
he was recently recognized vv ith the H. Flem-
ing Fuller Award, given annually to someone
whose ov\ n dedication to the highest stan-
dards of patient care and community service
minor that of its namesake.
"Receiving the Fuller Av\ard was reallv
something."" Hamrick sav s. "I was qLiilc
moved.""
The recognition is a highlight in a career
admired by others and relished by the
avvard"s recipient. "I've just had a great Jour-
ney here."" Hamrick say s.
Hamrick was born in the small western
North Carolina town of Rutheifordton. in the
Ashev ille and Shelbv v icinity. Considering
his famiK hisiorv. it was somethini: of a sui-
prise thai he went into medicine.
"I should have been a lawyer."" he recalls
with a laugh. "Lawyers go way back in my
family. I wanted to do something different, I
think. There was no epiphany, if you will.
There was no great calling. In deciding what
to do. I looked for a challenge and something
about medicine attracted me.""
Hamrick graduated from UNC in 1961
and entered the Navy. At that point, he says,
"I wasn't sure v\hat I wanted to do."" Once the
medicine bug bit. he entered the UNC School
of Medicine and graduated in 1967. It was
during his third year of medical schoi)l that
he decided pediatrics was for him. "It just
seemed to fit."" he says. ""I like working with
children. And pediatricians are generally
low-key people who have a lot of patience.""
From 1 97 1 -72. Hamrick was in private pe-
diatric practice in VV'inston-Salem. but UNC
20
Best-Loved Pediatrician'
- and the idea ofteaching - drew him back to
Chapel Hill, w here he's remained e\ er since,
working and teaching as a pediatrics general-
ist. "1 had ai\\a\s wanted to teach and felt so
comfortable in this setting." he says. "1 like
watching \oung people discover things
themsehes and see their self-confidence
grow, ^'ou can almost measure it b\ the
month."
"I ha\ e not regretted coming back here."
.According to his colleagues.
Hamrick"s students are glad he made that ca-
reer mo\e. as well. "Dr. Hamrick generates
enthusiasm about an\ clinical problem he en-
counters in a patient - regardless of how rou-
tine - and can infect the resident or student
with that enthusiasm." sa\s .Stiles, who was
one of Hamrick's residents in the I97()s. "l
would say that Hamrick exemplifies w hat
most of the pediatric residents in our depart-
ment see as the pediatric generalist. He is
also clearly the most popular role model for
residents in the department."
In fact, one colleague believes Hamrick's
invohemeni in teaching - parlicularK his
work in honing UNC's residencv program -
IS what he will be best remembered for. "The
e\cellence of the residencv program is his
legac\." says Roberta Williams. MD. former
chair of pediatrics. ""We ha\ e one of the nmst
competitive training programs in the country.
He has carelullv nurtmed the program and
served as its best role model."
Hamrick marvels at how medicine has ad-
vanced over the past .^O-plus v ears. "Tech-
nology has certainly changed - MRIs and CT
scans are just amazing. And look at immu-
nizations. For example, in the last 10 years,
one of the most serious forms of childhood
meningitis has been all but eratlicated bv an
immuni/ation."
But the evolution of the managed care
trend troubles him. "HMOs have been verv
disruptive of care." Hamrick says. ""The
strong relationship between physician and
patient has been fractured quite a hit bv that."
While Hamrick does not work in the clini-
cal setting as much as he once did. his pres-
ence in the Held remains strongly felt. ""He is
consistently diligent, compassionate, careful
and unpretentious." Williams savs. "He
maintains the highest standards of clinical
care and expects the same of others. He ap-
proaches problems with knowledge and w is-
dom. hiMiiorand sensiliv itv."
Now approaching fi(). and with main of
Rcsidvni Riiiiiiiie hrluiri. /<■//. miJ Hamruk uilk will; .Icnnitcr Bnullcx of Snow C
imp.
his friends and colleagues hav ing alreadv re-
tired. Hamrick understands that retirement is
in the not-too-distant future. But the notion
of hanging up his w hile coat leaves him a bit
uneasy. Retiremcnl would allow him to bet-
ter cnjov such favorite hobbies as swimming
and spend more lime with wife .Ann; their
two children. Anna, an allomev specializing
in medical malpractice law. and James, a
fourth-year LINC medical student heading to
the L'niversitv of California at San Francisco
for residency; their s|iouses: ami ;i new
grandchild, his fust.
"'I really don't leel like retiring."
Hamrick says. ""Nol yet. But whatever I do. I
w ant to be verv useful at it."
The H. llemiiig liillei .Awartl is in-
tended as a permanent memorial to
Kinston physician H. Fleming Fuller,
who died in 1986. A founding member
ol the board of directors of North Car-
olina Memorial Hospital. Fuller served
on the board from 1971 until his death
The l-"ullei Award is bestowed on some
one based on these attributes:
• Unwavering personal connnitment to
treating patients w iih compassion and
respect
• Ongoing serv ice as a staunch advo
cate for maintaining the highest stan-
dards of patient care and well-being
— both ]-)hv sical and emotional
• Flffectiveness as a professional role
model foi the siudents and voiing
physicians responsible lor the cue ol
future generations
• .Sense ol civ ic res|ionsibiliiv through
active participation in grou|-)s or orga-
nizations concerned with the health
and well being ol \oilh ('.Molina's
cili/ens
1 Ins V car's lecipieiil will be aiinounceJ
Sepl'l.S
Faculty
Notes
Christopher C. Baker, MD, FACS. pro-
lessor of surger\. v\ as recently appointed to
the Committee on Surgieal Education in
Medical Schools for the American College
of Surgeons. Baker also served on the Amer-
ican College of Surgeons" Committee on
Trauma and is currently a member of the
Curriculum Committee for the Association
for Surgical Education.
Janice M. Dodds, Edl). associate profes-
sor of nutrition, has re-
eei\ed the Catherine
Cowell Aw ard from
the American Public
Health Association's
food and nutrition sec-
lion, of w hich she is
chair. The award,
sponsored by Mead
.lohnson Nutritionals.
rect)gni/es excellence
and achie\enient in
administration, plan-
ning, mentoring and team biulding in public
health nutrition, and includes a cash prize.
Dodds specializes in community-based in-
ter\entions to imprme nutrition and studies
leadership de\elopment with a focus on
management in public health nutrition with
women and children. She is also serving on
the N.C. Institute of Medicine's child health
task force as chair of the health promotion
subcommittee.
I)a\ id .\. (lerber, MD. assistant profes-
sor of surgery, recenth recei\ed a Eaculty
Research Fellow ship from the American
College of Surgeons. Gerher will receive
S.^5.000 annually for two years, during
w hieh time he will be working on the isola-
tion and identification of a hepatic progenitor
cell pt>pulation. Further analysis will look at
llie antigenicity of these cells and how this
would impact their potential in li\ercell ther-
ap\ as an alteniali\e to solid organ transplan-
tation.
Robert N. Ciolden. MD. professitr and
chair of psychiatrv. has been appointed to the
editorial board of Depression and Anxiety.
Golden has also been appointed to a three-
\eartenn on the Scientific .Advisory Panel of
the .American Psvchiatric Institute for Re-
search and Education. The Institute, an affili-
ated organization for the American
Fs\ chiatric .Association, is charged v\ ith es-
tabhshuig the leadership role of the AP.A in
IN REMEMBRANCE
W. F'aul Bijijiers, .MD. 62. died April .S. 2( )()(). leaving
a legacy as a caring physician and a teacher of physicians.
He was an integral part of the University of Niirth Caroli-
na since becoming a medical student in 1959. Dr Biggers
completed his residency and joined the faculty in 1968.
He offered an example of compassion, scholarlv devd-
tion. ;ind commitment to patient care.
Beyond these contributions. Dr Biggers had a lifetime
interest in speech and language and served on the Board
of Examiners for Speech and Language Pathologists and
Audiology. Through tireless efforts, he ensured that the
state Legislature established and continued a program
designed to aid children with speech and hearing disor-
ders. This program has already benefited thousands of children w ithin our state.
For these elforts. he was presented the Service to Mankind Award and also was named
the 1999 H. Fleming Fuller Award winner as the outstanding clinician at UNC Hi>spitals.
(A profile about Dr Biggers appeared in the Winter 1999 issue of this publication.)
In recognition of Dr. Biggers" many contributions. George Sheldon. MD. and
Harold C. Pillsbury. MD. led etYorts to rename the Carolina Children's Communicative
Disorders Program the VV. Paul Biggers. MD. Children's Communicative
Disorders Program.
Just w eeks prior to his death, the W. Paul Biggers. MD. Distinguished Professorship w as
established. Dr Biggers requested that the Professorship be awarded to a physician who
shares his passion for innovative teaching. Indiv iduals wishing to make a donation ti> the
endowment of this new Iv created professorship should contact The Medical Foundation of
North Carolina. Inc. at ( 9 1 9 1 966- 1 20 1.
contributing to the scientific basis of psychi-
atric practice and policv .
Sharon Rin^^vvalt. MS. clinical assistant
professor of sjieech and hearing sciences,
has been appointed the Orange Countv
Preschool Interagency Council's representa-
tive to the board of the Orange County Part-
nership for Young Children, for a three-year
term. Ringwalt currentiv is the co-chair of
the Health and Early Intervention Grants Re-
vievv Committee for the Partnership.
(;e()rj;e K Sheldon. MD. Zack D. Owens
distinguished professor and chair of surgery,
has been awarded an honoran fellowship by
the Philadelphia Academy of Surgery, the
oldest surgical society in America, for his
contributions to the improvement of the sci-
ence of surgery and the education of sur-
geons.
Sheldon has also been unanimouslv se-
lected as an honorary fellow of the Society of
Black Academic Surgeons. The classifica-
tion of honorary fellow is the Society's most
coveted recognition and is bestowed on
those \\\w have distinguished themselves
through outstanding achievement and dedi-
cation to the objectives of the Society.
Sheldon w as most recently elected as an
honorary fellow of the Royal College of Sur-
geons of England, an independent, profes-
sional body committed to promoting and
advancing the highest standards of surgical
care for patients. He will be admitted to the
College at a ceremony in October
Sheldon, surgery ehainnan for 15 years, is
the chair of the Association of American
Medical Colleges, an organization dedicated
to improv ing public health by enhancing the
eflectiveness of academic medicine. He is a
fomier president of the American College of
Surgeons, the American Surgical Associa-
tion, the American
Board of Surgery and
the .American Associa-
tion for Surgery of
Trauma. The author of
more than 300 articles
and book chapters.
Sheldon has held edito-
rial board appointments
at several national
peer-reviewed medical
journals. Shchlcn
Alumni
Notes
60s
Marvin R. (ioldstein, MD '65. has been
practicini: canJiolog\ in Scottsdalc. Ariz.,
for 30 \cars. He and his w ife. Michelle,
crossed the Pacific and back (7.000 miles i
in their sailboat. Upon their return. the\
found out they were pregnant with tw ins.
now age two. Mar\ in can be contacted at
iiiarx goldC« speedchoice.com.
Benjamin K. Ward, Jr., .MD "67. w as
named Rotarian Man of the Year in I9W by
the Florence. .South Carolina Rotar\ Club.
He is a urologist with Florence L'rologic
.Associates.
70s
Cynthia I). Conrad. MI) '78. has a new
position w ith Connecticut Valley Hospital,
the state's long-temi psychiatiic hospital, as
Chief of Professional Senices.
Jonathan S Krauss, MD '78. recentl\ ac-
cepted an earl\ retirement offer from the
Medical College of Georgia where he has
been a professor of pathologs'.
80s
Charles B. Nemen.fl. MD '81. PhD '76.
was recently recei\cd the William C. Men-
niger Award for contributions to mental
health by the American College of Ph> si-
cians. He will recei\e the award ne.\t
.April in Philadelphia at the ACP's annual
meeting.
William Uinkenwerder, .MD "81. was re
cently named to the Board of Directors of
the .American Association of Health Plans
and was elected fellow of the American
College of Physicians. Fie currently ser\es
as e\ecuti\e \ ice president and \ ice chain )f
Blue Cross/Blue .Shieki of Massaclui sells.
Mare Randall. Ml) -HI. iscuneniK chair
and William A. Mitchell Professor of Radi-
ation Oncology at Indiana University
School of Medicine. This year, he w ill serve
as the President of the Medical Staff of Chil-
ian Health Partners Inc.. the consolidated
hospital system of L'ni\ ersit\ Hospital.
Riles Hospital tor Children and Methodist
Hospital of Indiana Inc. Marc and his w ilc.
Brabsie (BS "79). have three children: Ken.
1 4; Morgan. 1 2 and Marycobb. 10.
Tobia.s Schifter. MD "86. is a diagnostic ra-
diologist and nuclear medicine specialist in
Phoenix. Ariz. He recently was appointed
president of the Arizona Radiological Soci-
et\. His two-year term stalled Januars 2000.
He can be reached at tschiftercp e\ di.iiet.
Phil Thwing, MD '84. is engaged to be
married to LeAnne Keicher. His email
address is: PhilThw ing(?' Greene. xtn. net.
Lawrence W yner, MD '83. is a renal trans-
plant surgeon at Charleston .Area Medical
Center in West Virginia. He and his w ife.
Louida. announce the birth of their second
child. Tessa Anneliese. who was born No\.
,^0. 1999. Their son. Joshua Ross, celebrat-
ed his third binhda\ in .luK.
Fresno. He
kin>:bibbvfe aol.(
reached
90s
Brian Hamilton, MI) "91. moved to Ann
Arbor. Mich., in 1991. where he completed
his radiology residency and tellowships in
cross-sectional imaging and interventional
radiologv. In 1997. he moved to Charlotte,
where he joined Mecklenburg Radiology
Associates. He and his w ife. Kim. recently
welcomed triplets (Lila. Oliv ia and Mc.Alis-
terl to their familv.
C. Kins Bibhy ,|r., .Ml) '92. finished iwo
years as a general suigcrv rcsKlcnl al ['C-
San Francisco belore complclmg familv
practice residency at Medical College of
Virginia in Richmond. Va.. and becoming
boaril ceinlied in 1997. Bihby is now com-
pleting his general surgery residencv at I 'C-
Catherine C. Betor, MD '93. gave birth h)
Nicole Canada Betor on Oct. 19. 1999. She
works as a pediatric ophthalmologist w ith
Morganton Eye Physicians. PA.
Cynthia Cowan Bennett. MD '93. and her
husband. Scott Bennett. Ml) 9.^ gave birth
to tw ins. Ouentin Thomas and Oliv ia Judith
on Nov. 23. 1 998. Bennett and her husband
are in private practice in Gastonia and can
be reached at cindv-louCn gndusa.net.
N ictoria Carrett, MD "96. a lesident at
Children's Hospital of Michigan, helped de-
sign a program that recentlv receiv ed a
Community Access to Child Health plan-
ning grant, funded bv Wyeth Lederle Vac-
cines and awarded by the American
Academy of Pediatrics. The program,
called Teaching Children How to Raise
Children, is designed to give teen-aged
mothers in Detn>it the skills ihev \kw\ lo
care for their children.
23
Development
Notes
Dance Marathon raises
$70,000 for Kids
The second aniuuil LJNC Dance Marathon
raised S7().()25.98 to henefit the patients of
the N.C. Children's Hospital — nearl\ dou-
bling its first-) ear collection.
The Medical Foundation and ever>'i)ne at
the N.C. Children's Hospital is extremely
gratetul for the endless effort and enthusiasm
gi\en by the participants of this year's Dance
Marathon." said Jim Copeland. president of
the Medical Foundation of North Carolina.
Inc. "Their achievements are remarkable.
They are a shining example of what Carolina
students are capable of when they pull togeth-
er for a great cause — children."
The Dance Marathon is the largest
fundraiser for the Children's Hospital and is
organized solely by L'NC students. More than
70 students danced for 24 hours beginning at
7 p.m. Feb. 25 to raise money for the Chil-
dren's Hospital. The Dance Marathon com-
mittee has purposely left this money
unrestricted because its members want it
a\ailable for the programs and patients most
in need.
Last year, the Dance Marathon raised
$40. 00,^.8.5 during its inaugural event, mak-
ing it a first-time success story. Organizers
this year broke last year's total in part b\ also
hosting a silent auction of donated items. The
auction alone brought in S 1 2.2.56.
MAA Supports High-Tech
Health Sciences Library
L'NC's Health Sciences Library has
received S4().00() from the Medical Alumni
Association and its Medical .Alumni Loyalty
Fund. This is the second pa\iiient of a fi\e-
year pledge totaling $2()0.()()6.
The pledge is a gesture of the Association's
commitment to the Library's Capital Cam-
paign, an initiati\e to renovate the library
building to meet the changing needs of phy si-
cians. faculty, staff and students in the 21st
century. The Medical .Mumni Association
has a history of supporting the Library . Since
1 49 1 they ha\ e donated a total of S325.0()0 to
assist the Library in pro\ iding inno\ati\e
health information sy stems and ser\ ices.
Campaign goals include creating teaching
James Harper. MD. and Jane McNeer.
Irii^liO. present Carol Jenkins with a $40JI(H)
clicik far the L'NC Healtli Sciences Library.
labs, an electronic classroom with teleconfer-
ence capabilities and cutting-edge media
kitchens, where students, library staff and
faculty collaborate to make electronic course
materials. The kitchens v\ ill contain all the
necessary ingredients, such as network con-
nections and digital \ ideo softw are. to create
the most effective set of matenals for both the
teacher and student.
Though the renovation is not intended to
prov ide increased space, it will offer users a
redesigned space for learning and teaching.
"We want to make the Library a warm and
inv iting gathering place for everyone who
takes advantage of our resources. At the same
time, we need to be as high tech as possible,"
says Carol Jenkins. Health Sciences Library
Director.
Former UNC researcher
honors his late wife with
$1 million donation
A fonner UNC researcher has given more
than SI million to establish fellowships hon-
oring his late wife. The fellowships would
benefit future scientists with the UNC Neuro-
science Center.
James R. White. PhD. a retired UNC pio-
fessor of biochemistry, has transfeiTcd stock
valued at S 1 .028 million to The Medical
Foundation of North Carolina, Inc., to fund
the Helen Lyng White Fellowships in Neuro-
science Research.
■"Follow ing my vv ife's death. I tried to de-
V elop a vv ay to honor her memory in an ap-
propriate way." he said. "Since most ot
Helen's research in the years just prior to her
death w as directed toward the dev elopnient of
drugs to treat afflictions of the central nervous
sv stem, it seemed appropriate to somehow
promote research in the neuroscience area.
Fortuitously, at UNC-Chapel Hill the Neuro-
science Center had just gotten underway."
said White.
"This endowment is a wonderful gift and
sincerely appreciated by all of us at the
School of Medicine." said Jane NL McNeer,
V ice president of The Medical Foundation of
North Carolina. Inc. "Many young scientists
for years to come will be the true beneficia-
ries. This gifi will make a real difference in
research at the Neuroscience Center."
James White met Helen Lyng w hile they
were both doing research w ith the DuPont
Co. in Wilmington. Del. Follow ing their mar-
riage in January 1955. Helen, a 1952 graduate
of Russell Sage College, continued her edu-
cation at the University of Delaware, where
she received a Master's degree in radiation
chemistry . In 1 962. they came to UNC. w here
James joined the faculty of the medical
school. Helen received her PhD in biochem-
istry in 1967. Thereafter, she Joined Bur-
ixHighs Wellcome Laboratories.
When Glaxo purchased Burroughs Well-
come, she and other scientists fomied a com-
pany called KPI, which is still located in the
area and focuses on studying nerve grow th
factors and antidepressants.
Helen While died of cancer in 1997.
■ ^"^^H William D.
F ^^^MkJ^0 Snider. MD.
director of the
Neuroscience
Center, said it
"is anticipated
that the inter-
est from this
endow nient
would support
TK^^ the salaries of
"^^ two post-doc-
toral fellows.
The success-
ful applicants
would bear the title "Helen Ly ng White Fel-
low in Neuroscience Research."
Helen Lxni; White
President's
Letter
Final Grcetiriiis.
li has been an honor and a pleasure to
serve as president of the Medieul Alumni As-
stx:iation this past year. I ha\e enjoyed nian\
opportunities to partieipate in \arious eere-
monies and meetings that in\ol\ed alumni,
faculty, students and friends of the medical
school.
At the White Coat ceremon\ and at gradu-
ation, it was a treat to share the excitement
and anticipation of students at the beginning
and the end of their school experience. These
are some impressi\e young people about to
enter the profession who will be a credit to
their alma mater.
The N'omia Berrxhill Lecture brought to-
gether many longstanding and new faculty
and friends to he reminded once more of the
rich heritage we share though our school.
Regional alumni meetings were well at-
tended and w ere a time of fellow ship and an
opportunity, for Dean Houpt to discuss the
state of the school. I'm sure those who made
the effort to attend were gratified b\ the expe-
rience.
My favorite e\ent is the Spring Alumni
Meeting. The turnout this year was outstand-
ing. Aside from my being somewhat micro-
phone-challenged, the program went well.
The recipients of the .Alumni Distinguished
Service Awards certainlv represented the
best that the School oi .Medicine stands for.
Presenting Harold Roberts the .Mumni Dis-
tinguished Facull\ .Award was the highlight
of the Near tor me. Ron Neal's remarks in an-
nouncing the scholarship endowment in Dr.
Roberts" honor epitomized the sort of impact
he had on many who trained and vsorked
under him.
Dr Bud Harper has ccrtaiiil\ taken on his
duties as .Associate Dean for Alumni Affairs
with relish and finesse. (As an aside, compar-
ative golf scores of Dr. Harper and Dean
Houpt are a state secret I) Of course.
Stephanie Stadler makes the alumni office
runassmoothl\ as it does
Acknowledgments would be incomplete
without thanking John hnisi. abl\ supporteil
b\ the .Medical Foundation Stall, tor his un-
relenting efforts on behalf of the Lo\alt\
Fund. Congratulations are in order to the
Class of '.SS for their outstanding contribu-
tion this \ ear
For our school to continue to progress and
prosper the referendum on the bonds tor cap-
tial projects in the uni\ersit\ system must
pass. .Anyone v\ho will speak on behalf of the
bonds at ci\ ic clubs, churches, etc. can con-
tact the Dean's otTice for speaking points or
other assistance. "\'our help is needed.
Finalh. thank you for >our support this
\ear 1 know \ou will enjo> having Paul Viser
at the helm in the next year
GonhmBLiCnmJ.MI). Vo
-« »vx'
ME/Alumni Calendar
June JO, 2000 - Chapel Hill
McdiLcilcL'al Semiiuir 2()()()
June II, 2000 - Chapel Hill
Palhology aiul Laboratory Medicine Update tor the Praeticint;
Patlioloyist
June 16, 2000 - Chapel Hill
Ol'RR Regional Worksliop
Julv 7-10, 2000 - Chapel Hill
IJeiiientary & Adoleseenl IHACCII Summer Trainini;
July lO-Aug 4, 2000 - Chapel Hill
Preschool TKACCH Summer Trammt;
Jul\' 21-23, 2000 - Amelia Island. FL
Heart F-aikire Maiiagemeiil 2()()1)
Julv 21-23, 2000 - Research Triangle Park, NC
Neurode\elopmeiital Variations
Julv 10- August 4. 2000 - Chapel Hill
Preschool TEACCH Summer Traming
Hlementary & Adolescent THACCH Summer Training
I-or more information about CME courses, contact the Ot'fice
ot Continuing Medical Education. (919) 962-21 18, or toll-l'ree
through the Consultation Center. (800) 862-6264. To contact
the Alumni Affairs office, call (919) 962-6786 ore-mail
medical alumni C"' med.unc.edu.
Estate Planning Notice
Many individuals would like to make a major gift
to the UNC medical center, but cannot commit
current assets for such a purpose. Through a will,
however, anyone can make a more significant gift
than they might ever have thought possible by
designating a specific sum, a percentage, or the
residue of their estate for the benefit of the medical
To provide a bequest, simply include a paragraph
in your will naming The Medical Foundation of
North Carolina, Inc. as a beneficiary. For example:
"I give, devise and bequeath (the sum of$ ,
or ( % of my estate) or (the residue of
my estate) to The Medical Foundation of North
Carolina, Inc., a 501(C)(3) created to maintain
funds for the UNC medical center with principal
offices located at 880 Airport Road, Chapel Hill,
North Carolina."
This language creates an unrestricted bequest for
use by the medical center when and where the need
is greatest, or you may specify that your gift be
used for a particular purpose.
For further information on bequests, contact
Jane McNeer at (9 1 9) 966- 1 20 1 , (800) 962-2543,
orjmcneer@email.unc.edu.
Nonpi-Dfit Organization
U.S. Postage
PAID
Chapel Hill. NC
Permit No. 24
PERIODICALS DEPARTMENT
HEALTH SCIENCES LlBi^ARY
CAROLINA CAMPUS 7585
Summer :(HM)
Medical Alumni
BULLETIN
School of Medicine, University^ of North Carolina at Chapel Hill
W Reece Berryhill, MD
The Father of
Modern Medicine
Walter Reece Berryhill, MD
lOOth anniversary of his birth stirs memories of enormous contiibutions to UNC
By Karen Stinneford
Nearly tour decades after Waiter
Reece Berryhill. MD. stepped
dow n as dean of ttie UNC Sciiooi
of Medicine, his \ ision and intlu-
ential leadership li\es on.
It is evident in the initials ""MD" that ap-
pear on Carolina diploma's behind e\er\
medical school graduate's name.
It is evident in patients from towns such as
Grifton and Monroe and Hamlet who ha\e
access to high quality care at one of the coun-
try's finest academic medical centers.
It is evident in the hundreds of doctors,
nurses, pharmacists and dentists working in
medicalK underscrxed areas of the state with
the support of the N.C. Area Health Educa-
tion Centers program.
.As stated b\ one of Berryhill's fonner stu-
dents and faculty members in a letter nomi-
nating his mentor for the Universitvs
prestigious O. Ma.x Gardner Award. "Dr.
Berrvhill has always seemed to me to exem-
plify the characteristics of one who has done
most to benefit the human race."
Berryhill. the architect of modem medical
education at Carolina, was born near
Charlotte on Oct. 14. 1900.
.A staunch Scotch-Presbyterian. Berryhill
intended to pursue a career in the ministry
when he enrolled at Carolina in 1917. Figur-
ing a minister needed to be well-grounded in
the classics, he studied Latin. Greek and
English, even w inning the Eben Alexander
Prize for the best English translation of a se-
lected Greek passage. With characteristic hu-
mility. Berryhill later downplayed the
achie\ement by saying the prize wasn't a big
deal — he w as the only student who compet-
ed for it and besides. "I needed the S 1 0."
But modestv can't hide the accomplish-
ments of a young man determined to make
the most of his education. During his under-
graduate years at Carolina. Berryhill ser%ed
as president of the senior class and head of
the student council and was inducted into Phi
Beta Kappa.
Sometime during his junior \ear. Berryhill
decided to become a doctor instead of a min-
ister. He also met the woman w ho would be-
come his w ife and. years later, his partner in
Waller Recce Bcriylull. MD
\,<nh C,m,lm,l Colic, lun, I 'mveism nl ,V..;1/; Cun^lliui Uhuii-. al Cluipcl llil
building the medical school and hospital at
UNC. ^
Benyhill met Norma Connell of Warren-
lon one Saturdav afternoon at Peace College.
He had gone there to \ isit a girl from home,
but upon finding her holding court with a par-
lor-full of male suitors, he was introduced in-
stead to Miss Connell. who accompanied
him to the college chapel for a chat.
During their visit. Berryhill proceeded to
shock the pious young lady w ith questions
that seemed heretical. "Could God fry an egg
on a snow ball'.'" he asked her.
"He didn't have the gift of gab. and I didn't
ha\e the gift of gab. and he just trying to find
something to say." Mrs. Berryhill recalled re-
cently. "He was trying to shock me to start
the conversation and so he borrow ed a tech-
nique from Horace Williams, his philosophv
teacher, who would ask shocking questions
to make people think and talk."
When he graduated from Carolina in
192 1 . Berryhill lacked money for medical
school, so he returned to Charlotte and
taught in local public and private schools
for two vears. carefulh sa\ ing for a retum
to Chapel Hill.
Since it was founded in 1S79. closed in
ISS.'^ and re-opened in 1890. the UNC
School of Medicine had struggled to ex-
pand its curriculum beyond a tw o-year pro-
gram of gross anatomy instruction and
science labs. In 1902. the University's lead-
ers added an additional two years of clini-
cal instruction by tapping the resources and
patients in several Raleigh hospitals. The
effort failed for lack of state funding and by
1910, the University was back to teaching
the basics in a two-year program. Its med-
ical students had to attend other colleges to
procure their medical degrees.
Berryhill received his medical degree
from Harvard in 1927 and was an intern
and resident in medicine at Boston City
Hospital before mo\ ing to Belmont for a
short stint in priv ate practice.
In 1929-30. he pinch-hit in the class-
room of Isaac Manning. MD. dean of the
UNC School of Medicine. When Manning
asked Berryhill to teach a physiology
course, the latter replied that he didn't
know enough physiology to conduct it.
"Well. Reece. then this is a good way to
learn some more!" Manning responded.
Whate\ er his initial qualms about teach-
ing. Benyhill clearly had the gift of — and
love for — classroom instruction, and from
that point on practiced medicine in an acade-
mic setting.
Berryhill and Miss Connell married in
August 1930. and she accompanied him to
Cleveland where he was first chief resident in
medicine and later attending physician at
Lakeside Hospital and an instructor at Case
Western Reserve University. The Berryhills
returned to North Carolina in 1933 when he
accepted a position as chief physician at
UNCs student infirmary. A short time later,
he became an associate professor of medi-
cine.
Bern hill rose quickh through the ranks of
the medical school, becoming assistant dean
in 1937 and acting dean in 1940. When he
became dean in 1941. he was just 41 years
old — the youngest man ever appointed to
the position. Mn _\ outh didn't impede his \ i-
sion. Legend has it Bern hill so belie\ed Car-
olina needed a four-\ear. degree-awarding
medical school that he extracted a promise
from then-Uni\ersit\ president Frank Porter
Graham to help make it happen.
Bern hill's timing — that ot World War II
— would pro\e pro\ idential. .At the same
time Berr\ hill began his et't'ort to expand
UNC's medical school, men throughout
America were enlisting in the armed ser-
vices. North Carolina men were called to
serve, too. but many were rejected as being
physically unfit. The state ended up w ith one
of the nation's highest draft-rejection rates.
Why w ere North Carolina men — many of
whom toiled in the strenuous labor of farm
and textile work — physically unfit for
armed sen ice' Poor nutrition w as one cause,
but a bigger factor w as access to got)d med-
ical care. Being a predominantls rural state.
North Carolina lacked enough phvsicians to
adequatelv care for its population. As a re-
sult, many injuries and illnesses went un-
treated, vshich affected the overall health of
the state's citizens.
The embairassment of ha\ ing one of the
countrv 's worst draft-rejection rates spurred
North Carolina's legislature to create seseral
commissions and public-ser\ ice campaigns
to promote better health. This otfered Berrv -
hill the perfect opportunity to sell his \ ision
of what the state's tlagship university could
do to for her citizens: train more primarv -
care doctors w ho. in turn, could treat more
people.
To accomplish this. Berryhill said. Caroli-
na needed a four-year medical school.
Carolina needed a hospital
where medical students
could gain \aluable clinical
experience and where com-
munitv -based ph\ sicians
could send their patients tor
specialized care. .And Car-
t)lina needed to encourage
medical students to work in
small-town practices, and
also lend support to the
physicians alreads serving
there.
His \ ision became the
blueprint forlodav's L'NC
.School of Medicine. I'NC
Hospitals and the N.C. Area
Health lulucation Centers
program.
William B Blsthe. MI).
Marion Covington profes-
sor of medicine, called
Berryhill's timing fortu-
itous. Not onl) was the .N.C.
General Assembly con-
cerned about the poor health lhi\ lu\i,iiii
of citizens, but mans men in / nivcisin \
political pow er w ere former classmates ol
Bern, hill's. The\ quicklv embraced his opin-
ion that the University should be part of the
solution.
■'In the m4()s. the leadership of this state,
bv and large, had come from Carolina —
they were Berryhill's schoolmates, and that
■good old boy' network helped him iremen-
douslv." Blv the said.
In I'-UV. the General .Assemhiv provided
S5. 240. ()()() to build a 4()()-bed hospital in
Chapel Hill. The money also was used to ex-
pand the School of Medicine building and
build domiitories for nurses and house physi-
cians. Two years later the General Assembly
appropriated another $2.3 million to com-
plete these projects.
In an undated op-ed column Bcrrv hill
w rote shortlv before N.C. Memorial Hospital
opened in 1952. he lauded how these im-
provements would benefit all North Carolini-
ans.
"With this increase in the annual output of
doctors, largely residents of the state; with in-
creased facilities for the training of nurses,
technicians and aides in various medical
fields: and vv ith increased consultation and
postgraduate education facilities available,
the state should be well along the road toward
solv ing its most pressing health problem —
the lack of adequate personnel." he stated.
The UNC School of Medicine graduated
its first class of MDs in 1 954.
While Berrvhill carefully built a medical
school and hospital in the 195()s and early
196()s. he did so without any fanfare or self-
promotion. Indeed. Berryhill's inodesty and
humilitv vvas renowned anions; students and
facultv. Even the most comprehensive book
to detail the history of the L'NC School of
Medicine. "Medical Education at Chapel
Hill: The Eirst Hundred '\'ears." barelv men-
tions BeiTvhill and his legacv at all — a tact
that seems strange until one happens to note
he w as an authoi'.
"Dr. Berrvhill had a strong devotion to
dutv. vshich was manifested in a strong devo-
tion to the L'niversitv of North Carolina and
to the state." Blv the said. "The University
and the medical school were his religion —
he had no desire for self-pre)motion and he
never took credit for anv thing. He just want-
ed what was best for the l'niversitv and med-
ical school."
William W. McLendon. MD. emeritus
professor of pathologv and laboratorv medi-
cine, said Berrv hill possessed a number of
characteristics that made others admire him
as a leader His ability to carefullv listen to
and weigh other peoples' opinions before he
made a deliberate and final decision com-
manded respect. He knew everv' faculty
member and student bv name. He sought out
faculty meinbers w ith strengths different
from his ow n and gave them the autonomy
the\ needed to fulfill their professional po-
tential.
Most of all. Berrvhill possessed enonnous
personal and professional integrity, said
McLendon. who recounted the following in-
cident:
"One day. Dr Berrvhill got word that his
barn w as on fire." McLendon said. "He had
the keys to the state car in his pocket because
he was going to Raleigh that afternoon to ap-
pear before a legislative study commission.
No one would have
blamed him for jump-
ing III the stale cai and
dri\ mg oul to sec
about his burning
barn, but Or BeiTvhill
wouldn't have even
coiisuieicd doing
that. Instead, he
w a Iked around the
medical school until
he found a lacullv
memlx'i whose car he
could bniidw ami
ihcii he iliovc the bor-
row cd car niii 111 ihc
bain "
I'hvsicians like
Berrvhill who trained
during the I92()sand
1 9.^()s were encour-
aged to develop im-
|iosing. stem
countenances to help
uiulerscore then |iro-
( ( iiil j'lh'id ('I iIk II( iiIiIi AIIciiis vainpits wiiihdii.i \ ilu
iiiiui UiHi Id the Mule's I ili:(n\.
( iiiiliiiiitJ (III /'i;i.'i /"
Faculty Profile
Relishing tlie challenge
L;
By Melissa Matson
Diaz likes a challenge.
Il\ a characteristic that has
shaped his medical career
ind ser\es him well as the
new chair ol the Department of Der-
matology.
Born and educated in Peru, Diaz
had no idea that he'd spend the
greater part of his adult life in the
United States. Nor did he have any
idea that after 10 years as chair of
dermatolog\ at the Medical College
of Wisconsin, he'd lea\e his position
and the state he called home to mo\ e
to North Carolina.
Life in Peru
Diaz considers himself fortunate ^^^
to have attended medical school in
Peru in the late 196()s. "The medical
school was new, though it was p;ul of
one of the country's oldest uni\ersi-
ties founded by Liberator Simon de
Bolivar in 1824," said Diaz. "It was
affiliated with a brand-new teaching
hospital w hich meant we had the lat-
est technolog\ and teaching." '-'"'> ^"'-"- ^^I^
Follow ing his last year in medical
school. Diaz accepted a residenc\' position in
inlenial medicine. During that \ear, he decid-
ed that he w anted to become a specialist. "In-
ternal medicine was too general for me,"
said Diaz. "I needed a field I could go more
in-depth in."
Coming to the U.S.
He had planned to finish his training and
practice medicine in Peru. But a challenge
from some classmates made him consider
other options.
"It ne\ er crossed my mind to come to the
United States," said Diaz. "But w hen I found
out that two classmates v\ere taking a United
States licensing exam, I had to take it tt)o."
Diaz passed the exam in \^M. and shortly
thereafter, the job offers began rolling in.
"My timing was good," Diaz said. "Man\
U.S. hospitals at that time were suffering
from a shortage of physicians."
But before Diaz could accept an offer, he
had to resohe an issue in his personal life: his
relationship with Dora, his long-time girl-
friend. "I asked her to maiTX me in October
1969," said Diaz. "We got married that De-
cember, and two weeks later, we mo\ ed to
the United States."
Furthering his education
Diaz started his training in the United
States as a medicine intern at New York's
Ellis Hospital. He found himself well pre-
pared for w hat he'd tace that first year.
""Mn clinical training in Peru exposed me
to so many patients, so I was wav
ahead of my peers clinically." said
Diaz. "The challenge for me was
the language banier."
During his time at Ellis Hospi-
tal, Diaz considered more careful-
ly the areas of medicine in w hich
he might specialize. He
knew he enjoyed dermatology,
and he was intrigued by im-
munology. So he applied
to residencies that offered the
chance to study both.
At the Department of Derma-
tology at SUNV-Buftalo, Diaz
found exactly what he was look-
ing for — a nourishing communi-
ty of immunologists and the
beginnings of a tleld called im-
munodermatology. Among his
mentors were nationally recog-
nized dermatologists Dick Dob-
son, MD, his department chair,
and Thomas T Pro\ost, MD. w ho
later became chair i)f dermatol-
ogy at Johns Hopkins School of
Medicine.
Following his residency, he ac-
cepted a fellowship at Mayo
Graduate School of Medicine in
Rochester, Minn. It was during
his fellowship that he began re-
search into two autoimmune diseases of the
skin, pemphigus vulgaris and pemphigus fo-
liaceus. research he continues to this da\.
"Pemphigus \ ulgaris and pemphigus Ibli-
aceus are rare but serious autoimmune blis-
tering disorders of the mouth and skin." said
Diaz. "Before 1950. people would die with
no treatment. Toda>'. we can treat people w ith
steroids and immunosuppressive agents. Un-
fortunately, we don't know the cause of
human autoimmune disease."
Beginning an academic career
Once Diaz finished his training, he had a
decision to make.
".■\t that point. I was the father of two chil-
dren and had offers to go into private prac-
tice." said Diaz. ""But I was atlraclcd b\ the
variety in academic medicine, ihe challenge
of doing research, patient care and teaching."
So in 1976. he joined the L'ni\ersity of
Michigan as an assistant professor of demia-
tology. His chair ga\e him a lah for his re-
search and start-up funding, then sent him
out on his own. "I saw patients a few days per
week to generate a salary and w rote grant
proposals to gel funding for m\ research.""
said Dia/. "I had to pro\ e myself.""
During his years at Michigan. Dia/ had the
chance to expand his research outside of the
United Slates. He knew that an endemic tomi
of pemphigus existed in Bra/il. He also kneu
several people at the Uni\ersit\ of Sao Paulo.
and subsequentl) was in\ited to join them as
a \ isiting professor
"Brazil was the perfect place to conduct
research."" Diaz said. "In certain regions, doc-
tors see several hundred patients per year
w ith a disease related to pemphigus. I \\ as
drawn by the opportunits to find out the
cause of the disease in Brazil, with the goal of
appK ing that know ledge to find the cause of
the same disease here in the L'.S.""
In 1982. Diaz and his junior fellows left
Michigan for Johns Hopkins. There he se-
cured his second National Institutes of
Health grant and further expanded his re-
search in Brazil. ""It was exciting to work on
the frontier of research in the U.S. one da\.
and be in the remotest regions of Brazil the
next."" said Diaz.
.All told. Diaz spent six \ears at Johns
Hopkins. While there he was made the
schcHtls fourth full professor of dcmiatolog).
His first chairmanship
In I9XN. the .Medical College of W'lsccn-
sin made Diaz an otter he coukln"t refuse —
a chance to establish the college's llrst tle-
pariment of dermatology.
"When 1 got there." said Diaz, "the) onl\
had six residents and a part-time laculls
member. So I was starting from scratch "
That was a challenge he relished. He stall-
ed by hiring faculty for a laboratory and then
hired clinical people. Ten sears later. Diaz
said. Wisconsin had one of the best dermatol-
og_\ programs in the midw est.
His claim is not without suppiirt. In IWS,
Wisconsin"s demiatolog\ department ranked
14th in the nation in NIH funding. In the
same year, UNC w as ranked 1 1 th.
His department's residency program also
won a prestigious aw ard from the American
Academy of Dermatology that recognized
excellence in innovati\e teaching. The resi-
denc\ program included a two-month rota-
lion at the Uni\ersity of Sao Paulo. Brazil.
Department of Dermatolog\. (Note: This
exchange program has been transferred to
UNC and made a\ ailable to residents here. )
Coming to Chapel Hill
In earl> 1999. Diaz recei\cd letters Irom
se\ eral search committees — one from the
University of North Carolina. They wanted
to inters iew him for their dennatology chair-
manships.
"1 woke up to a new reality then."" Dia/
said. "First-grade institutions were interested
in me. That created a restlessness in me as 1
thought about the possibilities.""
True to form. Diaz recognized that new
challenges were w ithin his reach. He decided
to go through the inler\ iew process. In the
end. he chos'e L'NC.
"UNC was quick w ith its offer. '" said Diaz.
"".And 1 saw here the chance to establish a
strong research collaboration between our
faculty and those in the departments of im-
munology and epidemiology. That was \er\
impoiianl in ni\ own research."
His vision
Diaz joins UNC"s dermatolog\ depart
ment at what he sees as a pivotal lime. ' The
department has a wonderful national ie|iLita-
tion."" said Diaz. "But the departmenl is going
through a transition as one generation of
leadership is taking a step back. I w ant to es-
tablish lounilalions that will help Ihe depart-
menl atlvancc bevdiul w here il has been "
Luis A. Diaz, MD
Born:
September 16. 1942, in
Cascas, La Libertad, Peru
Wife:
Dora
Children:
Luis. Jr., MD. 29:
Fernando, 24: and Carlos, 22
Personal
Computers, cooking.
interests:
mo\ ies and fishing
Became
U.S. citizen
: 1982
Those foundations include making the de-
partment attracti\e to a new generation of
demiatologisis who might otherw ise choose
private practice. They also include making
sure his department is prepared for the in-
e\ ilabililN of increased ci>mpetition.
■"You know, up until now. we dermalologi-
cal clinical practices al man\ medical
schools ha\en'l reall\ had to wori_\ aboui
w here the mone\ will come from."" said Dia/.
"But now many are experiencing the stress of
competition w ith managed care. I wani to
make sure we"re ready for il here.""
If there"s one thing that this current presi-
dent of the SocieU for In\esligati\e Derma-
tology w anis to make sure others know about
him. it"s that he"s a team player "Fxe been in
academia lor most i>f in\ career and ha\ e
seen many different management si\les. in-
cluding divisi\e t)nes."' said Dia/. "1 look for-
ward to working w ith this administialion ami
my colleagues to further the work begun
here. .And 1 will do m\ hesi lo lullill ihc mis-
sion of this departmenl in palicnl care, med-
ical education, research ,ind comimmil\
ser\ ice."" D
Teacher-Student kidne
UNC Hospitals and gain;
By Karen Stinneford
An otherwise routine ii\ ing-donor
kidney transplant at UNC Hospi-
tals captured the national media
spotlight last April when Jane
Smith, a middle-school science teacher trom
Fayette\ ille. gave a kidney to one of her stu-
dents, Michael Carter
The human-interest appeal of the
"teacher-student kidney transplant" story at-
tracted reporters from media outlets such as
People magazine. The New York Times. NBC
Nightly News and Dateline NBC.
Michael had been bom with renal dyspla-
sia, and a result, one of his kidneys failed to
grow and function \\ hile the other functioned
only minimally. He began undergoing dialy-
sis treatment in June 1998. and his name was
added to LlNC's kidne\ transplant waiting
list in March 1999.
The poignant story unfolded when .Smith
watched Michael, now 15. toss a football
with some other students on the playground
at Max Abbott Middle School last year.
Smith knew nothing about MichaeTs
medical condition while she watched him
throw and catch the ball. To her. it seemed he
was "a step or two behind the other kids each
time." which she attributed to the baggy
pants and shiil he w as wearing.
During a break in pla\. Smith told Michael
that if he wore tighter-fitting clothes, he
could keep up with the other students. He
replied that he wore loose clothes because he
was undergoing dialysis three times weekl\
and the loose clothing made the procedure
more comfortable.
As Smith would later describe it at a new s
conference, the con\ersation w ent like this:
"You're not on dialysis." Smith said in dis-
belief.
"T am. too." Michael said. "1 need a
kidney."
"Well. 1 ha\e two — do you v\ant one of
mine?" Smith replied.
Although Smith's offer to donate a kidne\
was a spontaneous gesture, it was a sincere
one. She ga\ e Michael a slip of paper with
6
her name and home phone number on it. and
told him to give it to his mother. Deborah
Evans. Carter did. and when his mother
didn't call immediately, he pestered her.
At the news conference. Evans recalled
that she was hesitant to contact Smith be-
cause she didn't want her son to get his hopes
up. About a dozen of Michael's relatives had
been tested as potential donors and no one
matched. The likelihood that a teacher from
the school playground would match seemed
slim. E\ans said.
Yet Michael persisted. Every time he
passed his mother in the hall at home, he
asked whether she had called Smith yet.
"She's the one. Mom — I just know it."
Michael told his mother repeatedly.
So E\ans made the phone call, and soon
Smith was at UNC Hospitals undergoing
tests to detennine whether she was a suitable
match for Michael. She was.
The transplant w as scheduled to take place
in December, but was postponed when
Michael de\eloped an infection just prior to
surgery. In April. Smith and Michael were
admitted to UNC Hospitals and this time,
they felt, the surgerv w as meant to take place.
Mark W. Johnson. MD. director of the
renal transplant program at UNC. removed
Smith's kidney laparoscopically on Friday.
April 14. before handing it off to David A.
Gerber. MD. assistant professor of surgery,
for transplantation into Michael.
Other members of Smith and Michael's
medical team included: Elizabeth Friedman.
RN. transplant nurse coordinator post-op;
Debbie Sue Gipson. MD. pediatric nephrolo-
gist: Becky Knotts. CCSW. clinical social
w orker; Lynn McCoy, RN. CNN. renal trans-
plant nurse coordinator: Ann Morris, RN,
nurse practitioner; and Beverly Rodegast,
RN. transplant nurse coordinator post-op.
By the morning of Monday. April I 7.
Smith had recovered sufficiently enough to
appear with Michael's mother and Gerber in
live inter\iew s on The Today .Show. Good
Morning .America and MSNBC. They also
conducted interviews with NBC
Nighilx News, which sent a film crew to
UNC Hospitals.
Later that afternoon, they held a nev\ s con-
ference for TV. radio and print reporters from
throughout North Carolina. Subsequent
news stories appeared in USA Today. The
Wall Street Journal 's Southeast Edition, the
Atlanta Journal-Constitution, the Boston
Globe, the Chicago Tribune and Houston
Chronicle, and aired on TV stations in
Cincinnati, Cleveland, Dallas, Detroit.
Kansas City, Los Angeles, New York.
Philadelphia, Phoenix, Salt Lake City and
San Francisco.
Smith left UNC Hospitals follow ing the
news conference, just 72 hours after her kid-
ney was removed. She returned to her class-
room about two w eeks later.
"I feel fantastic." Smith recently stated. "If
it weren't for the reminder (scar) on my ab.-
domen. I really wouldn't know I'd done it. It
only took three weeks to feel I had full ener-
gy again."
Michael's mother also reported that he is
feeling belter than he has in years.
"Michael is doing great." Evans said,
adding that doctors have given Michael per-
mission to start playing his beloved basket-
ball again.
Both families gave high praise to the
health-care providers and staff at UNC Hos-
pitals.
"Regarding m\ thoughts about the doc-
tors, nurses, transplant coordinator, public-
relations department, food service and
transportation at UNC Hospitals — well, let
me just sa\' I am proud to be a UNC alum-
nus," Smith said. "The skill, care, instruction,
counseling and support v\ere amazing. Drs.
Johnson and Gerber are phenomenal men.
Their know ledge and concern for the patient
gi\e confidence and comfort, and I w as ne\ er
anxious for one moment. They are a credit to
their profession.
"I just can't say enough about m_\
enormously positive experience at
UNC Hospitals."
E\ans agreed. "I've been to other hospitals
with Michael and felt I had to w atch him con-
stantly." she said. "But at UNC. I knew
I could lea\e his room and go to the cafeteria
and be comfortable v\'ith that situation.
ransplant takes place at
lational media attention
Jane Small and Mliluwl Carter spend same lime reading: i;cl well wishes an a pra\ir c lunn liiniiiini; in MuluuTs hospital ,
W'c fell so secure. I knew Michael was in
;ju( id hands"
Since her surgen. Smith has been honored
at. and in\ ited to speak at. conferences recoy-
ni/in<; the \aluable contributions of vohin-
teers or promoting awareness about organ
donation. She is pleased with how the news
media has portra\ed the transplant.
"The media interest was unbelie\ahle —
and persistent, as I am still getting calls." she
said. "The coverage has been, vv iihoul excep-
tion, tremendous!) supporti\e of the process.
ms profession as a teacher and m\ faith. I re-
ally can't complain uhen the press is so posi-
tive about issues 1 care sodeepl\ about."
.■\nd if her and Michael's story persuades
one person to consider becoming an organ
donor, she said, the media attentitni will be
well worth it.
According to the Carolina Donor Ser\ ices
in Durham, about 67.()()() Americans current-
ly are av\ ailing a life-sas ing organ transplant.
Thirteen people on the national wailing list
die e\ery day. and some 4.S.'i,S people died in
1998 when organs did not become a\ailable.
A new patient is added \o the national organ
waiting liste\ery 16 minutes.
In North Carolina. nearU 2..^(HI people are
awaiting an organ transplant. l'eo|ile ages IS
and older can indicate their tlesire to donate
by signing a donor card and expressing their
wishes to family members. kelati\es can do-
nate a deceased family member's organs and
tissues regardless of that person's age.
.As many as 50 people can benefit from
one person's decision to donate. For more
information about beci>ming an organ donor,
people can call The Coalition on Donation
at (SOO) .V^.'i-SHARI: or \isit the
organi/ation's World Wide Web site
www. shares ourlife.oii; [J
Top mouse geneticist he
By Leslie H. Lanj;
The intcriiiilionally renowned
mouse genetieist. Terry R.
Masinuson. MD. reeently joined
the UNC Sehool of Medicine to
head a new genetics department and ge-
nomics initiative.
Magnuson. one of the most sought-after
scientists in mammalian genetics brought
with him his entire 13-member laboratory
group from Case Western Reserse
University.
In his tenured appointment as Sarah
Graham Kenan professor and chairman of
genetics, Magnuson became founding head
of the medical school's newest department.
The program will be housed in a KM). ()()()-
square-foot human biology research build-
ing currently under construction w ith a
combination of public and private funds.
TeiTy chose UNC over many other op-
pi)rtunities, some of which offered substan-
tially larger resources than we currently
ha\e." said Jeffrey Houpt. MD. dean of the
.School of Medicine. "He was intluenced by
the exceptional science programs here, the
careful planning of our needs and strategies
and the collegial atmosphere of the entire
research community."
During visits to Chapel Hill. Magnuson
took particular note of the reality behind
Carolina's reputation for interdisciplinary
research.
"It's a very collegial place, and that's
w hat struck me when I came through. \er-
sus other institutions I visited." he said. "If
one wants to put together a uni\ersity-w ide
center, it seems nn>re likely to happen at
UNC because of the culture. .-Xnd I find that
very exciting."
Funding also was an important factor in
Magnuson's decision to come to Chapel
Hill. The School of Medicine \\i\\ recei\e
$2.6 million over
four years from the
Howard Hughes
Medical Institute to
help develop and
staff its new genet-
ics center.
"The genetics
center will comple-
ment existing re-
search strengths at
UNC in the study of
mouse models of
diseases, genetics of
model organisms,
cancer research and
clinical genetics."
said William F.
Mar/luff. MD. ex-
ecutive associate
dean for research at
the School of Medi-
cine. "The nmney
will establish the
genomic core tech-
nologies we need on
campus and a chro-
mosome imaging
facility for detecting
alterations in cancer
as well asabnonnal-
ities in genetic dis-
eases."
Of 1 05 U.S. med-
ical schotils competing for the Hughes
grants. UNC was among 41 winners.
Awards ranged from $1 .6 million to S4 mil-
lion.
According to Hughes olTicials. the suc-
cessful proposals emphasized collabora-
tions between researchers in basic sciences,
clinical research and bioinfonnatics. a field
that mairies computer science with molecu-
lar bioloev to anah /e the massise data
Tcny R. Magnuson, MD
being generated by the Ll.S. Human
Genome Project. The project by the U.S.
Department of Energy and the National In-
stitutes of Health will identify more than
lOO.OOO genes in human DNA. determine
the sequences of the three-billion chemical
base pairs that make up human DNA and
store this infonnation in databases.
"We're going to build a major genomics
program here at UNC." Marzluff said. "Ten
ids new UNC program
new School of MediLine facLiltx uill be
added in this area. \\ iih a locus on the genet-
ics of complex diseases. In addition, the
School of .Medicine and the College of .Arts
and Sciences w ill recmit at least fi\e neu fac-
ult> in bioinfomiatics."
,A portion of the Hughes grant will be used
to recruit four junior facultN working in
mammalian genetics by offering start-up
packages for equipping their laboratories and
pro\ iding support for technical personnel
and supplies.
Magnuson already has signed on se\eral
of the nation's lop assistant professors to
UNC. They include David Threadgill from
Vanderbilt University, Fernando de Villena
of Temple University and the Fels Institute
for Cancer Research, and Stanford's Charles
Perou. a young leader in cancer genetics and
micro-array analysis of multiple genes.
Perou's recruitment was done jointly with
the UNC Lineberger Coniprehensiv e Cancer
Center.
"In looking at genetics and genomics at
UNC-Chapel Hill. I see an incredibly strong
medical genetics effort spread across obstet-
rics and gynecology, pediatrics anil medi-
cine." .Magnuson said. "The cy stic fibrosis
center is entering into a national consortium
to look for modifiers of CF. Molecular diag-
nostics is important within the clinical de-
partments, and the Lineberger
Comprehensive Cancer Center has begun an
important research program in this area, as
well. There's genetic epidemiology, biosta-
tisiical genetics and nutrition in the School of
Public Health, all of which are important to
the success ol a genomics program."
According to Magnuscm. the ongoing
public and commercial genome projects are
generating an unprecedented amount of in-
lormation leading to a comprehensive dia-
log of all known human genes.
"And Irom this we're seeiiiL: cmeruiiiL'
technologies, new data on gene sequencing
and this is leading to greater e\pK>ration of
gene functiim." he said. "More than learning
the function of individual genes, what is real-
ly important here is looking at the function of
genes collectively, as interacting networks of
genes within the entire genome — this
means complex genetics and complex disor-
ders. And that's vv here the genome project is
allow ing us to go."
Given the inevitable explosion of genetic
and genomic information at the molecular,
organismal and population levels, the entire
biomedical research enterprise is undergoing
a paradigm shift away from hypothesis-dri-
ven research. Magnuson said.
"Now. having these vast amounts of cata-
logued infomiation. we have discovery-dri-
ven research; that is. we're analyzing this
information." he explained. "And this will
lead back to better hypothesis-driven re-
seiirch. After analyzing gene sequences, you
can predict functional relationships based on
sequence and then test these functional rela-
tionships. This is leading to incredible iiifor-
matii>n on genetic v ariances associated vv ith
disease predisposition and the prediction of
therapeutic responses to drugs. |the field ol'l
phamiacogeneties."
In Magnuson's v ision. a genomics center
contains key components in adi.litioi) to the
science.
"We must deal not only with the science
and scientific discoveries but vv ith health-
care issues, the business enterprise, including
technology development and transfer,
bioelhics. and the legal and social impacts
of genomics iliscoverics on public policv."
he said.
"1 env ision biomedical engineering as an-
other key component to bring us fuilher into
imaging technology, microfabi icalion of
sensors, molecular diagnostics, ami arr.iv
lechnolo'jv." he adtled. ".And iheii ihcre arc
the educalional and training programs at all
levels — undergraduate, graduate, medical,
social, business. 1 think a genomics center
at UNC must encompass all these ditfeient
components."
Why the genetics initiative at Chapel Hill
now .' Houpt summed it up succinctly.
"L'nless you have an excellent program in
genetics, you'll be incapable of aspiring to be
a leading medical school or a leading univer-
sity in this country." he said. "This is one
dance vou can't sit out." D
CommeiTiorative plaque honoring W. Reece
Berryhill, MD, to be unveiled Oct. 10
A commemorative plaque honoring the contributions of fomier School of Medicine
Dean W. Reece Berryhill, MD, will be unveiled Oct. 1 0.
The plaque presentation will take place as part of the 1 6th annual Norma Berryhill Dis-
tinguished Lectureship.
The plaque, contributed by grateful alumni, contains comments made by University
President Francis P. Venable (1956-1934) during his University Day address in Chapel
Hill on Oct. 12, 1900. Venable's comments were published in the Charlotte Daily Ob-
server two days later on Oct. 14, 1900. the same day Berryhill was bom in a Mecklenburg
County community.
For both men, visionaries of their times, the sentiments would reflect the principles
upon which they based their administrations. The te.xt of the plaque is as follows:
"The University of a State, when it tnily fulfills its duty, should be its chief strength and
glory, a light for the people, the fountain-head of their higher life, the .source of their up-
lifting and upbuilding, the bulwark of their liberties. It moulds the leaders of the people.
Streams of inlluence flow from it to gladden the whole land. . ..Great movements for the
bettering of the condition of the people. . .spring from it.
"The founders of this State in their sturdy independence and far-seeing wisdom recog-
nized the importance of such an institution, and so, while the struggle for freedom was
still upon them, provided for the establishment of this University — the chief safeguard
of their children against the loss of those liberties for which they fought. And should
some one come and offer to endow this institution w ith many millions and remove it from
the control of the State, it wouldbeasaleof their birth-right of those children, a betrayal
of the trust of the fathers. The citizens of this State cannot afford to have this University
narrowed down to the political platfomi of any one party, to the creed of a single sect, to
the economic belief of any individual philanthropist. Parties, churches, philanthropists,
all can center their efforts here and unite in the making of a great people, a grand Com-
monwealth, but the people must control. The truest democracy in this State is found right
here — a w ise tolerance for all shades of opinion and belief."
The plaque, which depicts the images of both Berryhill and Venable. will be mounted
in Berryhill Hall.
Ciin/iiniiil Iniiii piii^t' .i
lessional authorit\, McLendon added.
Berryhill put his stern countenance to good
use.
"He was an imposing and intimidating
person, and it was the most dreaded thing to
get called to his office." McLendon said.
"One time a student got called to his office,
and Dr. Bern hill made him sit there while he
finished up some task. Finally, Dr. Berrvhill
said. "Do you like medical school?' and the
student replied v\ ith great trepidation, "Yes
sir. 1 do.' He said, 'Well, that's good because
you're in the top 10 percent of your class.
Keep up the good work.'"
When BeiTyhill stepped down as dean in
1964, he was named Sarah Graham Kenan
professor of medicine and became director
of the Division of Education and Research in
Community Medical Care. During the five
years he served in that position, he broad-
ened the Uni\ersity's teaching base by ar-
ranging hospital affiliations throughout
North Carolina. Out of these cooperative
arrangements — which provided full-time
faculty for the associated hospitals — grew
the N.C. Area Health Education Centers pro-
gram.
Today, some 28 years after it was created,
AHEC continues to help meet the primary
health care needs of the state by improving
the supply, distribution and quality of health
care professionals. Students who attend
UNC's medical or phannacy schools are re-
quired to complete nearly half of their clini-
cal rotations at AHEC sites.
For his work laying the foundation for the
AHEC program, Berrvhill was named a mas-
ter of the American College of Physicians in
1977 — the highest level an individual can
attain within the organization.
When he wasn't at the School of Medi-
cine. Berryhill loved working in his yard,
planting fiowers. trees and shrubs, and tend-
ing to the family's large vegetable garden. He
rareh went to his office in the summertime
w ithout takini: alona some tlowers or \eizeta-
bles for co-workers, students or patients.
An a\ id reader and classical music con-
noisseur. Berryhill lo\ed sports and could
rattle off baseball .statistics dating back to
the 1920s. It was an interest fueled when
Berryhill served as director of the student
infirmary and his task involved caring for
the university's athletes.
For someone uncomfortable v\.ith public
praise and accolades. Berryhill had to en-
dure much of both dunng his career He re-
cei\ed the O. Max Gardner Award and the
Cio\ernor's Distinguished Citizens Award
in 1964, and in 1971. former students and
house officers in his home county. Mecklen-
burg, honored him by creating the W. Reece
Berryhill Mecklenburg Medical Scholar-
ship.
In 197.^ the School of Medicine honored
him by naming one of its buildings Berryhill
Hall. The basic sciences building for health
affairs students cost slightly more than the
General Assembly's original 1 947 appropri-
ation for the hospital and medical school.
BeiTvhill retired from the faculty in 1 97 1 .
He died at the age of 78 on Jan. 1 .'|979, the
year that marked the centennial anniversary
of medical education at Chapel Hill. He is
buried at his beloved campus in the Old
Chapel Hill Cemetery.
One former colleague summarized
Berryhill and his career as follows: "Dr.
Berryhill's inherent Scotch-Irish modesty
and reticence would never permit him to
admit his towering contribution to this med-
ical center... hut so broadly ha\e Dr Berry-
hill's talents ranged and so inextricably is
his life interwoven with the fortune of this
school that one cannot mention one v\ ithout
thinking of the other." D
10
Contributions of Norma
Berryhill honored in
distinguished lecture series
Wi'
lie her husband.
\V. Reeee Bernhill.
MD. was bus\
buildine a deeiee-
conterring medical school and at-
filialed leaching hospital. Norma
Connell Bernhill was bus\ build-
ing a communit).
Indeed, "her hospitalit\ helped
con\ ince those young, hot-shot
medical faculty that this would be
a good place to teach and do re-
search and raise their families."
one colleague said.
Mrs. Berr\ hill's contributions
to the School of Medicine and
UNC Hospitals were so instru-
mental to their growth that a dis-
tinguished lecture series was
named in her honor. The Norma
Berryhill Distinguished Lecture-
ship takes place each fall and fea-
tures an accomplished School of
Medicine faculty member
Raised on a farm in Warren
Count\. the oldest girl among 10
children. Mrs. Berrshill met her
future husband in 1921 when she
was a student at Peace College.
After transferring to Carolina and
recei\ing her bachelor's degree in 1925. she
mo\ed to New York City and studied for a
master's degree in sociology while working
in a settlement house for immigrant women.
She married Bernhill in 19.^0 after returning
to North Carolina to ser\e as dean of girls at
Charlotte's Central High .School.
When Berryhill became dean ot the
School of Medicine, it had just 4,S tacults
members and a two-year curriculum that
forced students to complete their medical ed-
ucation elsewhere. When Berryhill stepped
down 2.'^ years later, the School of .Medicine
had 4.^.^ faculty members, was awarding
medical degrees and operated a highls re-
spected academic medical center
Persuading phssicians to come to Chapel
r
Norniii C.
Bernhill
Hill in the I94()s and early I95()s was a chal-
lenge. There was only one hotel in town —
the Carolina Inn — and few restaurants, so
the hospitalit) Mrs. BenAhill extended was
crucial to recruiting new faculty and helping
them feel welcome and connected after the\
arri\ed. She frequently hosted dinners
and teas for facults members and their w i\ es.
and it became a common sight to
see her taking lacults lamilies casseroles
or desserts.
"Chapel Hill was just a little southern \il-
lage — it vKasn't the town it was today." Mrs.
BerPthill said. 'Making new people feci wel-
come was just something neighbors did "
Kenneth Brinkhous. Ml), who fiisi \isited
the Berrvhill home in I'Mfi. recalled ihc
BeiTx hills' laiiious li(is|iiialit\.
"The school was \erN small
back then and there v\ as a feeling
o\' w armth and closeness." he
said. "Mrs. Berryhill lent grace
and dignity and was alw ays sen-
siti\e to the needs of faculty and
students. Her home was always
open, and that atmosphere of gra-
ciousness was so important in
helping recniit the faculty needed
to expand to a four-\ ear school."
Mrs. Bern* hill alsi) was instru-
mental in organizing the L'niver-
sit}, Woman's Club and creating
the N.C. Memorial Hospital Aux-
iliary. Now called the Volunteer
Association, the organization re-
cruits \ olunteers w ho donate
more than .'^2. ()()() hours of their
time to UNC Hospitals annualK .
Colleagues sa\ the late dean
fully appreciated the \alue of his
w ife's contributions, once re-
J marking, "she did more than ans -
j body."
1 This year's Norma Berr\ hill
Distinguished Lectureship
lakes place at 3 p.m. Tucday.
Oct. 10. in Gerrard Hall and fea-
tures George Sheldon, MD. Zack D. Owens
distinguished professor of surgeiy and chair-
man of the Department of Surger>'. Sheldon
is the chair-elect of the .Association of Amer-
ican Medical Colleges. He is one of less than
20 surgeons in the last 100 sears to ser\c as
president of all major surgical organizations,
incUuling the .•\merican College of Sur-
geons, the American Surgical .Association,
the American Association tor the Surger\' of
Trauma and the American Board of Surgery.
The authoi- of more than .^00 articles and
book chapters. Sheldon has held editorial
board appointments at se\eral national peer-
rev iewed medical journals. □
Faculty
Notes
Alice S. Ammerman, DrPH. RD, associ-
ate prcifessiir of
nutrition, is the
recipient ot the
Bernard G.
Greenberg Alumni
Endowment
Award. The
award is gisen
a II n u a 1 I y t o
an outstanding
lull-time faculty
member of the
.School of Public
Aininernuin
Health for excellence in the areas of pub-
lic health research, service and teaching.
Continuous demonstrated excellence in
service to the broader public health com-
munity over a number of years is a major
criterion of the award.
Paul F. Dunn, MSN, FNP, CDE. clinical
assistant professor of family medicine, has
been elected chair of the "Patterns of
Care" Taskforce for the NC State Diabetes
Ad\isory Council — a council appointed
by the gmernor. The taskforce has repre-
sentation from diabetes pro\ iders through-
out North Carolina directed toward help-
ing primary caregi\ers in their delivery of
diabetes care.
David Fensferniacher, PhD. research
assistant professor of pharmacology, act-
ing director of the Center for Biolnformat-
ics and director of scientific computing for
the School of Medicine, has recenth been
awarded a $5().()()() grant from the Small-
wood Foundation. The grant will be used
to establish both undergraduate and gradu-
ate student assisiantships in bioinformat-
ics. and also to de\elop a bioinlormatics
seminar series.
Adam O. Cold.stein, MD. assistant pro-
fessor of family medicine, was recently
presented with a certificate of apprecia-
tion, signed by N.C. Gov. James Hunt, in
recognition of dedication and outstanding
ser\'ice to North Carolina in his efforts
working with teen tobacco use.
Robert E. Gwyther, MD, MBA. piofes
sor of family medicine, was elected vice
president of the N.C. Academy of Family
Physicians. Gwyther recently traveled to
Moscow. Russia \\\lU a group from the
National Institute on Alcohol Abuse and
Alcoholism (NIAAA). where he partici-
pated in teaching techniques of alcoholism
inter\eniion to Russian phvsicians.
Timothy J. Ives, PharmD, MPH. clinical
associate professor of family medicine,
has been selected as a fellow by the 2()()()
L'.S. Public Health Service Primary Care
Policy Fellowship program.
Rehecca J. Laudicina, PhD. assistant
professor of clinical laboratory science,
has established the Hemochromatosis
Education and Screening Project with a
$200,()()() grant from the Kate B. Reynolds
Charitable Trust. The planned two-year
project will include an educational pro-
gram offered through the NC Area Health
Education Centers, and the screening of
low-income people in 14 western North
Carolina counties for this common genetic
disorder.
Warren P. Newton, MD, MPH. associ;ite
professor and William B. Aycock Distin-
guished Chair of family rnedicine, has
been appointed to the board of directors of
the NC Academy of Family Physicians.
David W. Ollila, MD. assistant professor
of surgery, has
accepted the posi-
tion of director of
the Multidiscipli-
nary Sentinel
Node Proizram at
UNC. Ollila com-
- '-■ pleted an NIH-
^^V funded surgical
^^^k ^m^^^^^^ oncology fellow-
^^H ^ ^^^B ship John
Wayne Cancer
OMo Institute. Santa
Monica, Calif., in 1997 and stayed for an
additional year as the assistant director of
surgical oncology. At the Ji)hn Wayne
Cancer Institute. Ollila trained with the
pioneers of sentinel lymphadenectomy in
melanoma (Donald L. Morton. MD) and
breast cancer (Armando E. Giuliano.
MD). Since arriving at UNC. Ollila has
helped to complete an institutional breast
cancer sentinel node validation trial,
which documents UNC's high accuracy
rate with the technique. Ollila is a member
of the American College of Surgeons
Oncology Group Breast Section, which
currently has two national sentinel node
protocols.
Ollila was also recently selected by
L'NC medical students for membership in
Alpha Omega Alpha (AOA), the only
national student honor medical society in
the world. The societv "s chapters annually
offer membership to a faculty member
who has distinguished themsehes in their
professional career.
Catherine N. Otto, PhD, MBA. assistant
protessor of clinical laboratiiry science,
has been appointed to the National Com-
mittee on Clinical Laboratorv Standards"
Subcommittee on Total Error for Labora-
tory Methods.
(Jeorge F. Sheldon, MD. Zack D. Owens
distinguished professor and chair of
surgery, has been awarded the Llni\ersity
ot Kansas Medical Alumni Association's
2000 Distinguished Alumnus Award in
recognition of his outstanding contribu-
tions to society and to the profession of
medicine. The purpose of this prestigious
award is to provide a role model and a
source of motivation for current and luture
medical students. The award is presented
to an individual who is a graduate of the
University of Kansas School of Medicine,
and who has made niileworthy contribu-
tions to the theory and practice of medi-
cine and to the health of all people
through patient care, research and teach-
ing skills. Sheldon received his MD from
the University of Kansas School of Medi-
cine in 1961.
Benjamin M.W. Tsui, PhD. professor
and director of research in biomedical
engineering, has been appointed vice-
chair of the department.
Alumni Association
Honors Five
The School of Medicine and the
Medical Alumni Association pre-
sented tl\e Distinguished Ser\ ice
Awards and the Distinguished
Facult) Award at its annual awards banquet
heldNia\.r
This year's Distinguished Service Award
recipients were: Walter R. Da\ is of Midland.
Texas: Otis N. Fisher. MD. of Greensboro:
James D. Hundle>. MD. of Wilmington; and
William L. London. MD. of Durham. The
Distinguished Faculty Award went to Harold
Roberts. MD. of Chapel Hill.
• .A nati\ e of Pasquotank County. Davis is
"^wp-*-=<C perhaps best
know n for his role
^ in spearheading
1 the creation of the
university's S23-
niillion central
Academic .Affairs
librarv that bears
his name. T h e
Texas business-
man not onlv
w orked to per-
suade the .N.C.
General .Assembly to fund the library w ith
the sale of university-owned utilities, he also
personally supplied the lO-acre facility with
books. Other university beneficiaries of
Dav is' generosity include the Educational
Foundation. UNC Press, the School of Social
Work and last year's Hurricane Floyd relief
efforts. Davis has served I I years on the
I'NC Board of Governors and 15 years on
the I NC-CH Board of Trustees.
In the medical school, the department of
ophthalmology has made dramatic improve-
ments in doctors' ability to track and treat di-
abetic eye disease, thanks lo considerable
funding from Dav is. His grants have sent fac-
ulty members overseas through the Doctors
Without Borders and Phvsicians for Peace
programs, Davis also put in countless hours
Davis
explaining to state legislators the fundamen-
tal need for the UNC Health Care, which
greatly enhanced the School of Medicine and
U.NC Hospitals' business tlexibility and al-
lowed it to compete more fairly in today s
rapidiv changing health-care miu-ketplace.
• Fisher is known throughout the stale as an
expert radiologist w ho steadfastly advocated
for updated and
expanded radiolo-
'^v g> facilities at
v'.hat is now
Moses Cone
Health System in
Greensboro. Fish-
er — w ho earned
his bachelor's and
medical degrees
at Carolina — has
demonstrated his
Fi\lier lov alty to his alma
mater time and time again through Schot)l of
Medicine fund-raising efforts and willing-
ness to work w ith Area Health Education
Center students.
Fisher has served in various capacities at
local and state levels as a member of the
boards of directors for the N.C. Chapter of
the American College of Radiology, the
Medical Board of the Mo.ses Cone Hospital,
the N.C. Medical Peer Review Foundation
and the Southeastern Angiography Society
— serving also as past president in the latter
two organizations. He is a member of the
Guilford County Medical Society and has
served as president and board member for
ihc Greensboro Academy of Medicine, as
well as serv ing on the boards of the Greens-
boro Heart Association and ihe Crippled
Children's Societv of Greensboro
• Huiidlev twice has been included in •■The
Best Doctors in America: Soulheasi Re-
gion" Having completed his iindcigiaduatc
and medical cdiicalioii. research rcllowshi|i
( ^
and residency at
Carolina. Hund-
lev has been an
active member of
the meilical
schtiol's .Alumni
.Association. .As-
sociation presi-
dent in 1998-44.
Alumni Council
member since
1990 and Nation-
al Loyalty Fund HiiiulUy
Committee member since 1994. he also
served on the search committee that selected
the department of orthopedics' first chair-
man and worked diligentlv to establish the
chair's distinguished professorship.
Hundley has been staff physician for the
Rotarv' Orthopaedic/Regional Crippled Chil-
dren's Clinic for nearly three decades, the
past nine years as medical director. For more
than 20 yeiu-s, he also sened as athletic team
physician for UNC- Wilmington and was
given the athletic department's William J.
Brooks Distinguished Serv ice .Award. In
1998. he was recognized with the establish-
ment of the James D. Hundley Outstanding
Student Trainer Aw ard. A past president of
the North Carolina Orthopaedic Association,
he serves on the Governor's Osteoporosis
Prevention Task Force and the National
Board for Certification of Orthopaedic
Phv sicians .Assisianls.
• .A petliatrician and pctiialric hemalologisi
for nearly 40 years. London is a 145 1 j'hi
Beta Kappa graduate of UNC. After allciul
ing medic.il school at UNC and completing
naming ai Children's Medical Center in
Boston. London returned to practice in ihe
Durham office established bv his uik Ic.
Throughout his practice. London has served
as ;i role model faculty member for meilical
sUklenis. residents and staff at L'NC Hospi-
tals. Ihe SchiH)l of Medicine. Duke Universitv
I.^
Medical Center, Durham Regional Hospital
and the lumier Watts Hospital.
An active member of the American Board
of Pediatrics since 1979. London served on
the board of directors for six years and was
secretary-treasurer for another year. He has
ser\ed as the long-time president of the N.C.
Pediatric Society,
and held numer-
ous leadership po-
sitions in the state
chapter of the
American Acade-
my of Pediatrics.
London was chap-
ter chaimian from
1969 to 1974. and
under his guid-
ance, the two state
London organizations —
once fragmented in their efforts — worked
collaboratively to champion programs for
children.
For
■ 40 Years follow ine his davs as an
undergraduate,
medical student,
senior resident and
fellow at Carolina.
Roberts has ser\ ed
on the school of
medical faculty as
an internationally
recognized special-
ist in hematology
;ind coagulation. His
curriculum vitae
includes member-
ships on committees and councils at the Na-
tional Institutes of Health, the National
Heart. Lung and Bhxid Institute and the Na-
tional Hemophilia Foundation. At Carolina,
he served as chief of the Division of Hema-
tology, director of the Center for Thrombosis
and Hemostasis. director of the Clinical Co-
agulation Laboratory and director of the
Comprehensive Hemophilia Diagnostic and
Treatment Center, the latter of which now
bears his name.
In recocnition of his work in the field of
coagulation. Roberts was granted the Distin-
guished Career Award for Contributions to
Hemostasis by the International Society on
Thrombosis and Hemostasis. where he
serv ed for 1 2 years as executive director. He
also was aw arded the society's highest honor,
the Robert P. Grant Medal, for his research
mlo the genetic basis of hemophilia. His tal-
ent as a teacher has been recognized by stu-
dents who awarded him the Medical Basic
Sciences Teaching Aw ard.
The Distinguished Service Award was es-
tablished in 1 955 to honor alumni and friends
whose careers and unselfish contributions to
society have added luster and prestige to the
LIniv ersity and its School of Medicine. The
Distinguished Faculty Award, first given in
1978. recognizes a full-time UNC faculty
member for excellence in teaching, contribu-
tions to medicine in the state, leadership in
continuing education of practicing physi-
cians and accomplishments in improving
communications between faculty, alumni
and people of the state.
.4 Snapshot of
Spring Medical Alumni Weekend
May 5-6,2000
Walter Davis, seated, shares a moment with Dean Jeffrey
L Hoiipt. MD.
Classmates, friends and faculty reminisce at the DSA Banquet at the
Carcliihi Cliih.
Sharitii; memories during a look hack.
The Class of '55 presents its lari^est-ever Loyalty Fund ijift of $150,000.
14
Fall Medical Alumni Weekend
October 20-21, 2000
UNC Fall Medical Aliunni Weekend Schedule
FRIDAY
OCTOBER 20, 2000
SATIRDAY.
OCTOBER 21. 2000
•^^Ml a.m. - 2:30 p.m. CME: Pre\enti\e Medicine: Screening and
Earl\ Management of Major Medical Dis-
eases Tlw GiOixi' Watts Hill Alumni Center.
Chapel Hill
Registration and Continental Breakfast
Welcome and Introductions. James R. Harper.
.MD. Associate Dean for Medical Alumni
Affairs
The Re\olution in Diabetes and its Manage-
ment: Implicatii)ns fe)r Screening. John B.
Buse. MD. Director Diabetes Care Center and
.Associate Professor of Medicine. Di\ ision of
Endocrinolouv
Break
11:3(1 a.m. -12:30p.m. Prostatic Malignancy: Decision Marking
Based on PSA Values. James L. Mohler. MD.
.Asscxriate Professor of Surger> and Pathology
& Laboratory Medicine. Member oi UNC
Lineberger Comprehensi\ e Cancer Center &
Director. Urologic Oncology
Lunch
Screening and Treatment of GI Malignancies.
Da\id F. Ransohoff. MD. Professor of Medi-
cine. Di\ ision of Dieesti\e Diseases
9:30- 10 a.m.
10 -10:05 a.m.
10:05- 11:15 a.m.
11:15- 11:30a.m.
12:30- 1:30 p.m.
1:30 -2:30 p.m.
3 -4 p.m.
6:30-7:15 p.m.
7: 15 -9 p.m.
Special Presentation: "Walter Reece
Berrvhill. MD. and the Expanded Medical
School at Chapel Hill." William W. McLen-
don. MD "56 Ge(>n;e Walts Hill Alumni Cen-
ter. Chapel Hill
Six'ial and Banquet. George Watts Hill Alum-
ni Center. Recognition of new Loyalty Fund
Associates, student scholarship recipients and
Endou ment Fund urant recipients.
S^M:id\-AlumniHalll.ll.lll
Dinncr-AlumniHalll.ll.Ili
(The schedule below is based on a "best guess" game kickoff time of
12:30 p.m. Kickoff is subject to change until 10 da\s prior to the
date. Call '^)lM-%2-SS4| the week pnor to the game to confimi kick-
off and morning e\ent schedule. Those u ho pre-registcr b\ the dead-
line will be contacted w ith an\ appropnate intomialion. )
8:30 a.m.- 12 p.m.
9 a.m.
9 a.m.
11 a.m.- 12:15 p.m.
*^ 12:30 p.m.
Reiiistration and Ticket Pick Up.
I siVloor Bern, hill Hall. UNC Campus
Council Meetmg. 103 Benyhill Hall
Reunion Campaiiin Stcerini: Committees
Meeting. 103 BerrNhill Hall
Classes of "46. ".51. "56. "61. '66. "71. "76. "SI.
"86. "^)1
Pig Picking, outside Berryhill Hall in the Stu-
dent Commons Area
UNC \ s. Clemson. Kenan Stadium
*4 TICKETS MAXIMUM. FIRST COME.
FIRST SERVE. Additional tickets may be-
come available closer to the game date. Contact
the Medical .Alumni Office at 9 1 4-462-884 1 .
ACCOMMODATIONS: Alumni are respon-
sible f(^r making hotel arrangements. Blocks of
rooms ha\e been reserved at: 1 ) The Sheraton
Chapel Hill/ (formerlv the Omm) - 414-468-
4900 (4/22/00 cutoff). SI 44-^. ID = UNC
Medical Alumni. 2) LaQuinta Inn & Suites
(1.8 mi north of 140/15-501 e.xit) -
4 1 4-40 1 -4660 ( 4/20/00 cutoff. Group #45 1 65 ).
,$72-1-. $44-)-. ID = l'NC Medical Alumni. A list
of additii>nal hotels in the Research Triangle
can be provided upon request.
(Print and Fax la the .Medical Alumni Oifice)
FAIL MKDICAL ALIMNI WEEKEND
REGISTR.\TION
Deadline: Oelcher .<. 2(10(1
Name
Class Year
Address
Telephone
Namc(s) of Guest(s)
*Social Security (CME only - optional)
Friday. October 20th:
CMliWoiiram
Berryhill Presentation
Social & Banquet
# C"' S65.(K) = %
# (no charge)
# (p S45,(K) = •«,
(prc-regislralion required)
Saturday, October 2Ist:
Council Vlcclini; #
Pig Picking: " Adult #
(i- 1 (i yo #
C"' $l().(X) = .'j.
(S' $ 7.(X) = $
Foolball Tickcls #
(MaMiiuiin (it 4 can be ordered!
Tolal:
@ $26.(X) = $
S
Method of Payment:
Check (payable lo Medical Foundation of NO
Credit Card: VISA Mastcrt^ard
Signature
Card #
Fxpiration:
KLliini I.. Medical Alumni Ott"icc. UNC-CH
C.B. # 7(MH). 126 MacNider Buildini:
Chapel Hill. NC :7.'^94-7(H)<)
Telephone: (414) 4()2 SS41 or l-S(M)-S62-6264 (ask lo
be connected). Facsimile (419) 466-1076
Email: Medical Alumni («' med.unc.edu
News
Briefs
UNC Hospitals ranked
among best medical centers
in the nation
Elc\ en niedic;il specialties ottered at L'NC
Hospitals rank anioiiy the lop 50 programs of
their kind nationwide, according to the Jul)
1 7 issue of U.S. News ami World Report.
"U.S. New.s has recognized what we al-
ready knew — that some of the best medical
experts and programs in the country are lo-
cated right here at UNC Hospitals," said Eric
Munson. president and chief executive offi-
cer. "That UNC Hospitals is consistently
ranked alongside such premier medical insti-
tutions as Johns Hopkins and the Mayo Clin-
ic speaks to the high caliber of our faculty
and staff anil the high quality of our patient
care."
To be ranked, a hitspital had to meet one of
three standards: be a member of the Council
of Teaching Hospitals; be affiliated with a
medical school; or provide at least nine out of
1 7 prescribed technological services. These
criteria winnowed the number of "rankable"
medical centers in the United States from
6.247 to 1.701.
U.S. New.t ranked the top 50 programs in
the following specialties: cancer; cardiology;
digestive disease; ear. nose and throat; eyes;
geriatrics; gynecology; hormonal disorders;
kidney disease; neurology/neurosurgery; or-
thopedics; pediatrics; psychiatry; rehabilita-
tion; respiratory; rheumatology; and urology.
LINC Hospitals" gynecology program
ranked 14th nationwide. Pediatrics ranked
22nd nationally — a first-time appearance on
the list.
■'How exciting it is that the reputation of
our pediatrics department is garnering such
prestigious acclaim just months before the
opening of the new N.C. Children's Hospi-
tal." said Alan Stiles, MD. chair of the De-
partment of Pediatrics. "We have tried to
establish a premier pediatrics program in
North Carolina, and I think this ranking sup-
ports our belief that we are succeeding in our
endeawir."
UNC Hospitals also appeared in the fol-
lov\ing other specialty rankings: cancer. 41;
digestive disease. 32; e;u", nose and throat, 26;
geriatrics, 22; hormonal disorders. 24; kid-
ney disease. 20; orthopedics. 37; respiratory
disorders. I S; and urolocv. 24.
Sanford Specialty Clinic
Expands Services
Just months following the opening of San-
ford Specialty Clinics in Sanford. UNC
Health Care has expanded its medical ser-
\ ices. Sanford Specialty Clinic now offers
endocrinology and osteoporosis care to its
services that initially included pulmonary
medicine and rheumatology.
Pulmonary specialist Jana Johnson. MD.
and rheumatology specialists Mary Anne
Dooley. MD, and .Alfredo Rivadeneira, MD,
provide patients medical care.
Diagnostic and treatment services are
available at the clinic for asthma, lung dis-
ease, osteoporosis, rheumatoid arthritis, in-
nammatory arthritis and tendonitis.
The clinic, located at 212 W. Main St. in
Sanford, is open from 8 a.m. to 5 p.m., Mon-
day through Friday. Groundbreaking for a
new facility is expected to take place this fall.
Spicer-Breckenridge lecture
focuses on medicine and art
M. Tliere.se Soiillii^iile. MD, Senior
Contributing Editor of the Journal iif the
American Medical Association, was the
keynote speaker at the 2000 Spicer-Breck-
enridge Memorial Lecture, held May 5.
Southgate presented "Some Affinities
Between Medicine and the Visual Arts."
Soulligate .selects covers and writes essays
for JAMA, and she also lectures for med-
ical societies, hospitals, museums, and
cominunitx groups.
UNC treats home health
patients with the latest
technology
UNC Home Health has gone high-tech,
thanks to a new program called Tele-Home-
care that allows home-health nurses to
"\ isit"their patients through telephones and
computers.
The technology of telemedicine isn't new.
For years now, doctors ha\e consulted each
other \'ia teleconference. And hospitals na-
tionwide ha\e established telemedicine sites at
satellite locations, allow ing doctors and pa-
tients in rural areas to "meet" with specialists
in more metropolitan areas.
For UNC. though. Tele-Homecare repre-
sents the first time the technology has been
used to care for patients in their ow n homes.
"We are only the second hospital in North
Carolina to use Tele-Homecare." said Zelda
Moore, a registered nurse and the program's
coordinator. "East Carolina v\as the first, and
they've primarily used it w ith patients who
have congestive heart failure, hypertension
and high-risk pregnancies. We'\e broken new
ground by using it to care for wound patients."
Using the new technology with wound pa-
tients was a natural for the home health nurses.
"These patients require a lot of monitoring,
and we can spend a lot of time visiting them,"
Moore said. "With telemedicine we can still
monitor the patients, keep the wounds healing
and use our manpow er more effecti\ ely "
Another plus for telemedicine is its tlexibil-
it\. If a nurse is concerned that a patient is too
sick for telemedicine care, the nurse can
change the plan.
"We can switch to home visits, or if we
think the patient is too sick for home care, we
can talk w ith the doctor about a clinic \ isit or
other medical evaluation," she said. "A peifect
example is the time 1 scheduled a Tele-Home-
care V isit with a patient on a new medication. I
noticed on the monitor that her face was
sw ollen. so 1 Jumped in the car and went to her
home for a more detailed assessment."
Another related application for the technol-
ogy is canng for bum patients.
"Bum patients have to return so many times
to clinic during their healing process." said
Anita Fields, a registered nurse who is burn-
care coordinator for the N.C. Jaycee Burn
Center at UNC Hospitals. "Now we can use
telemedicine to ease some of that burden."
Research
Briefs
UNC, Duke, starting search
for osteoarthritis genes
It's not difficult to find :i laniilN in uhicli
generation after generation has struggled
with the same inherited disease. The chal-
lenge is finding the genetic link to understand
how illnesses, such as osteoarthritis, are
passed dow n from parents to their offspring.
An international research network com-
posed of se\en uni\ersit\ medical institutions
including L'.\C"s Thurston .Arthritis Re-
search Center and Duke L'ni\ersit_\ Medical
Center ha\e just begun the kirgest studs e\er
to look for that link, the genetic susceptibilit\
to osteoarthritis.
The most common form of arthritis, os-
teoarthritis is a chronic condition that affects
more than 21 million .Americans. Bs analw-
ing DN.A and health histories from man\ pa-
tients, researchers belie\e the\ will better
understand the role that one or more genes
play in the condition's development. The
goal is to find nev\ and more effectix e medi-
cines. The academic research institutions are
working together u ith the Center tor Human
Genetics at Duke and Glaxo Wellcome, a
pharmaceutical conipan\.
For the lull Stan. \ce lutp://\\\v\\.uin .cdu
Au'us/newsscir/ivsccin li/i( inhiti 1 IJIOW.htiii.
UNC opens first clinical trial
of vaccine treatment for
advanced breast cancer
Doctt)rs at the Uni\ersity of North Caroli-
na at Chapel Hill ha\e opened their first clini-
cal trial of a \accine treatment for ad\anced
breast cancer.
.After more than four years of test-lube and
animal studies, researchers at the UNC
l.ineberger Comprehensi\e Cancer Center
will find out if intra\enous infusions ot their
genetically engineered protein fragments will
stimulate a person's immune cells to recog-
nize and kill breast cancer cells, causing ad-
\anced breast tumors to shrink.
"This breast-cancer \accine is not a shot -
it's a 'vaccine' because it should work by en-
hancing the patient's ovs n immune response
against their tumor." said l.ineberger member
Jonathan Serod\. .\11). associate prolessor of
medicine antl microbiology and immunolo-
gy-
"This is the tlrst use ot a \accinc directed
against a mollification ot a specific part of the
HER-2/neu protein found on breast-cancer
cells. People ha\e tried using engineered pro-
teins in the treatment of melanoma, but not
for breast cancer "
Study: too much sugar, not
enough milk may damage
U.S. teens' health
Between 19(1."^ and I ysift. a considerable
shift occurred in the diets of U.S. teenagers
that could compromise the future health of
the nation's people, a major new Uni\ersit\
of North Carolina at Chapel Hill stud\ shows.
On the horizon, researchers say. are more
strokes, heart disease, high blood pressure
and cases of the bone-weakening condition
know n as osteoporosis.
Total milk consumption dropped b\ close
to 50 percent among adiilescents o\ er the
three decades studied, they found. That de-
crease was accompanied by a hea\ y increase
in consumption of sugar-laden soft drinks
and fruit-fla\ored beverages. Teens also
began eating more of their \ egetables in the
fiinii of fatt\ fried potatoes than their parents
did.
".An increase in high-fat potato consump-
tion through French fries and hash browns
led to an increase in segetable intake, but the
number of ser\ ings of fruits and vegetables is
still below the recommended fi\e per day."
said Barr\ Popkin. PhD. professiir of nutri-
tion at the schools of public health and medi-
cine and one of the repint's authors. "Iron,
lolate and calcium intakes continue tt) be
below recommendations for girls."
A report on the findings appears in the Jul\
issue of Archives of Disease in Childhood, a
professional journal.
hnp://\\\yu:iiiie.edii/iieu s/neu\ser\/
rese(ir(h/popkinS(l724()0.lilin
Study seems to show >vhy
French sutter less heart
disease, cancer
University of North Carolina at Chapel
Hill scientists have discovered w!i\ a com
pound found in grapes and grape products
such as red wine shows natural cancer-figlu-
ing properties that might be importanl in pre-
venting or treating the illness.
The work appears to explain (he sci-called
"Irench |Xiradox" llic lad lliat Ircnch
people experience lower rates of heart dis-
ease death and certain cancers despite drink-
ins: nu>re wine on averaize than L'.S. residents
do.
Scientists finind that the substance, irans-
Resveratrol. or Res. modulates the activ it> of
NF-kappa B. a protein that attaches to DNA
inside cell nuclei and turns genes on and off
like a svv itch, the scientists found. Res appar-
entlx helps turn otf a natural protective mech-
anism in the body inviilv ing the protein that
prevents cancer cells from being killed, as
thev should be.
.A report on the work appears in the Julv
issue o\' Cancer Research, a scientific jour-
nal. .Authors are Minnie Holmes-McNary.
PhD. a nutritional biologist and postdoctoral
fellow at the UNC's Lineberger Comprehen-
sive Cancer Center, and her mentor Albeil S.
Baldw in Jr.. PhD. a biology professor who
also works at the center.
htlp://\\\\\\\itnc.edu/ne\vs/ne\\sser\/
researcli/hald\vin>l)63iH)l).htm
New national study shows
infection, fat embolism
important contributors to
sickle cell disease deaths
Unusual infections and lumps o\ fat called
emboli that clog arteries in the lungs appear
to be under-appreciated causes of acute chest
sv ndrome in sickle cell disease patients. The
syndrtmie. which is a group of debilitating
symptoms, is the leading cause of death
among sickle cell patients, according to a
major new studv .
Earlier diagnosis and more aggressive
treatment of those svmpioms might save
many victims of the illness, which is the most
common inherited disorder among black
people in the United States, researchers sav.
Improved treatment may include earlier
use of oxygen, more eftective antibiotics, in-
centive spirometiv and chest physical thera-
py in patients who develop the chest
syndrome, they say. When appropriate, earli-
er use of blood transfusion and mechanical
ventilation also should be considercti
.A report on the .'^O-medical cciiici suulv
appeared in the June 22 issue of the A'cir
l:ni;land .loiirnal of Medicine. Listed among
its authors was Fugene P. Orringer. MD.
UNC professor of medicine.
htlp://\v\\w.itnc.edu/ne\\ s/new sserv/
rese,n(h/orruf^\ll>')2liin.hnii
17
Alumni Profile
Paul Viser Assumes
MAA Presidency
By Katherine Kopp
Paul Viser, MD. recently installed as
president of the UNC School of
Medicine's Alumni Association, is a
man v\ ith a sense of mission.
■"r\e got two ver>' simple goals for myself
as president," said Viser in a recent interview.
"One is increasing membership in the alumni
association. The second is increasing the sup-
port, both tlnancial and in other arenas, that
alumni contribute to the medical school."
Viser. a native of Ahoskie and the son of a
UNC class of "50. has found satisfaction fol-
lowing in his father's footsteps. He graduated
from UNC in l^SO with a bachelors of sci-
ence degree in bicilogy. and credits the Biolo-
gy Department with supplying him with
more than just an undergraduate degree. "I
met my w ife. Diane, in my biolog) class." he
sa)'s w ith a laugh. "And for that reason alone,
it was probably the best class I ever took at
Carolina!"
After recei\ ing his MD from the UNC
School of Medicine in 1 984. Viser completed
an internship and residency in internal medi-
cine in Little Rock. Ark. Viser went on to
spend two years in Whitesburg. Ky., fulfilling
a National Health Ser\'ice Corps commit-
ment. "Whitesburg is in the coal mining re-
gion of Kentucky." explains Viser. "and there
is a lot of poverty there. Working there was
difficult in many ways, but it was also a very
v\ orthw hile expeiience."
After a brief sojourn in Winston-Salem.
Viser. his wife Diane and their three children
now enjoy quintessential small-town life in
Clinton. "When it was time to lea\e Ken-
tucky back in 1989. 1 looked at four different
practice opportunities." says Viser. "I nar-
rowed it down to two, one in Winston-Salem
and one in Clinton, and we chose Winston-
Salem. But after about six months, it became
clear to me that I realh' missed small-tow n
life. E\en though I was the fourth person in a
great group of doctors in Winston-Salem. I
just didn't feel it was the right fit for me."
Viser realizes that the life that suits him so
well is not for every physician. But he also
believes that there are many benefits — both
personal and professional — to being a
small-town doc.
18
Ptiiil \'iM'r and son Aaron prepaic dinner
for the rest of the family which includes
Ellen. 1 1, and Mark. 8.
"I know that some people think being a
doctor in a small town is like being stuck out
in the boondocks," he acknow ledges, "and I
do miss the camaraderie I had as part of a
group. Doctors who live in smaller tow ns and
rural areas can sometimes get out of touch, if
they don't keep up with reading journals and
CME opportunities. But I've found that, even
though I'm a solo practitioner. I share call
with five other doctors and handle an acti\e
hospital practice. It's a situation that's good
for all of us."
Viser shares office space w ith another
physician right next to Sampson Regiiinal
Medical Center, a land-grant hospital built
after World War II and, according to Viser,
one of the few independent hospitals left in
the state. Though he li\'es in a town of only
8,000 or so residents. Viser and the five other
physicians he shares call with draw from a
county population of 45.000 and beyond.
"Clinton is in the center of Sampson
County." Viser explains, "and 1-40 goes right
through the county. By land area, we're the
largest county in the state."
Viser feels he has the best of all wodds —
an independent solo practice, complemented
by shai'ed coverage and some shared expens-
es with other physicians, continuing educa-
tion opportunities through UNC and other
institutions that allow him to keep current
with new advances, and life in a small-town
where he is known and knows others. He is
active in the community, doing everything
from coaching softball to teaching Sunday
schot)l to \olunteering on behalf of the
Sampson Crisis Center, w hich pro\ ides food,
clothing and shelter to those in need.
He really enjoys the bonds that he has de-
\eloped w ith his fellow citizens in Clinton. "1
thri\e on the relationships that have devel-
oped," he says. "These relationships, with pa-
tients and with those in the w ider community,
develop slowly, over a period of time. You
just can't rush them."
Viser stays busy, seeing about 1 5 to 20 pa-
tients a day — "within the norms for in-
ternists." he says — rounding at two nursing
homes and making occasional house calls.
"My dad used to carry a big doctor's bag on
his house calls." Viser remembers. "He car-
ried everything you could think of: it was big
enough for a camping trip!"
"If a patient is tenninally ill or just got out
of the hospital." he says, "it's nice for me to
gi) to them and see how they're doing. That's
often hard to do in a practice in a larger
town." says Viser
An avid and lifelong learner, Viser is con-
stantly reading journals, discussing cases
w ith other ph>sicians. and attending confer-
ences to improN e his base of know ledge.
As president of the Alumni Association.
Viser plans to stay on his toes for the rest of
his tenn. "I hope to encourage more people to
attend our medical alumni weekends," he
says. "They're a great opportunity for contin-
uing education, and an even better opportuni-
ty just to see one another and catch up."
He also hopes to increase the le\el of fi-
nancial participation by graduates of the
medical school. And Viser, who is not afraid
to put his money where his mouth is, has
gi\ en regularly to the UNC School of Medi-
cine. "I spent eight very iinportant years of
my life in Chapel Hill," says Viser. "I owe my
li\ ing to that, and I'd like to do what I can to
encourage a feeling of loyalty and gratitude
toward the Medical School among my fellow
alumni." D
Match Day
^^^Kj ^ '* laP
^^Pr <^V
^^H
»^::i
CotiiiralulaluMis to the Class of 2(K)() School ot Medicine gradu-
ates. Nearl\ half ot the graduates entered a priniar\ caie residencs
program earlier this summer Check the list bekm lor the names of
residents coming to your program. Then, call them with a u elcome
loyourcitN ortown.
Visit the School ol Medicine Web site at
uw'M.niCil.uiu .cdu/Mi/iinnch/lii.srory lor more mlormation on
this and piexious matches. Those listed belou and on the Web
consented for their names to appear in public documents.
iforn
Alabama
William Trac\ Durham
California
Carols n Cell
Karen Marie Di\on
Susan Hunter Gibbs
Har\e\ James Hamrick. Jr.
Da\ id Laurence Issacs
Catherine Tung-Ling Lee
KimberK Susan Le\in
Madelena Michele Martin
Louise Dysart Met/
Zackary .S Moore
Nimesh Bhupendra Shah
Elizabeth .\ Steele
Colorado
.•\llison Dorbandt
District of Coliinihia
Katina Cieiger Barnes
Romulo Ernesto Colndres. Jr.
Nerissa .Marge Price
Florida
OluwatoNin Olarele .Ajose
.Mehin .Standford F-arland. Jr.
Sonja Trojak F-'rance
SamerTaj-Eldin
Johann Vincent Torres
(k'orgia
Sung K>u Chang '^I'i^Hl
Illinois
Zane Kesin Basrawala
Lisa Rahangdale
Taslor Hainer Stroiul
Indiana
Donald Lee Mcl.amb. Jr. ' n/!i/in/i
Michael Patrick Murphy "'"<'"^'
Internal Medicine
Pediatrics
Emergency Medicine
Internal Medicine
Medicine
Radiology-Diagnostic ( Ad\. )
Transitional*
Emergenc) Medicine
Pediatrics
Internal Medicine
Pediatrics
Psychiatry
Anesthesiology (Ad\.)
let of
Pediatric
Pediatrics
Pediatrics
Psvchiatrv
Pediatrics
Family Practice
Pediatrics
Internal Medicine
Medicine-Pediatrics
Medicine-Primarv
Urology
Obstetrics/(i\necolog\
Radiolosjv-Diag. ,
Emergency Medicine
Emergency Medicine
Colo
Vn\\. Alabama Hospital. Binningham
Childrens Hiispital. Oakland
.Alameda Counts Medical Center. Oakland
UC San Francisco. San Francisco
UC San Francisco. San Francisco
UC San Diego Med. Clr.. San Diego
Santa Clara Valle\ Medical Ctr.. San Jose
Stanford Uni\ersit\ Programs. Stanford
Loma Linda Univ. Med. Ctr. I.oma Linda
VC San Francisco. San Francisco
Stanford Uni\ersit\ Programs. Stanford
Loma Linda Uni\. Med. Clr. Loma Linda
Stanford Unixersitv Programs. Stanford
Colorado School of .Medicine. Denver
NCC- Walter Reed Arm\ Medical Center
Childrens National Medical Center
Georgetown llni\crsit\ Medical Center
Jackson Memorial Hospital. Miami . ,
Florida Hospital. Oriando > ^1'''
Uni\. Florid;i/Shands Hospital. Gainesville
Uni\. Florid.i/Shands Hospital. Gaines\ille
Jackson .Memorial Hos|iital. Miami
Emopv Uiii\ersii\, .Atlaiila
Loyola Uni\. Medical Ctr.. Mawvood
McCiau Medical Ctr Northuesiern. Chic;
Unnersitv ot Chicago Ho.pnal
Indiana Uni\.. Imlianapolis
Indiana Uni\.. Indianapolis
19
Kentucky
Andrew Craig McGregor nfiif^l
Maine
Kimberly Lyn Hartnett
Maryland
Janinc Elizabeth Billiard
William Aycock Mills, Jr.
Patrick O'Connell Mctr
Michigan
Leslie Renee Ellis
Mark Eric Hutchin
Mark Eric Hutchin
Minnesota
JetTrey Schiller Mueller
James Elliot Rider
Leonide Gerard Toussaint III
Massachusetts
Bi7an Courtney Batch
Sandra Charlotte Farkouh
David Laurence Issacs
Stephen Andrew Oljcski
Aneesh Kiuiiar Singia
Peter Anton /.emaif \laSSach
New York
Michael L;iJaun Cody
Kendreia Wynette i^ickens-Williams
Albert Hamilton Holt. Jr
Jenniler [illen Larson
Stephen William North
Patrice Lanette Reives
Elizabeth Cate Roede
William Douglas Schell
North Carolina
James Ritbert Alexander
James Robert Alexander
Albeil Muir Leonard Anderson
Frederic|ue Claude Marie Bailliard
Anne Wood Bea\'cn
JetTres \i. Brow n
Donna Michelle Capps
■Abigail Suzanne Caudle
Chanhthevy Sourisak Chai
Kimberley Renette demons
Kelli Gail Coop
Patricia .Ashles Coppatie
David Rodolph Dixon^
Brian William Downs
Brian William Downs
Cescili Aurelia Drake
Myriam Ruth Farkouh
William Mortimer Fowlkes IV
Carolyn Lonaine Hess
Shawn Brooke Hocker
Carolina Markey Hoke
Tenence Edward Holt
Jennifer Ann Hooker
Tracy Powell Jackson
Skyler Elizabeth Kalady
Sosena Kebede
Dennis John Kubinski
Ke\ in Michael Lee
Bartholomew Joseph Lopina
Kecha .AnnMarie L\ nShue
Uroloiiv (Adv.
General Surcerv
Pediatrics
Pediatrics
Medicine-Primary
Internal Medicine
Surgery*
Otolaryngology (Adv.
Radiology-Diag. (Adv.)
Internal Medicine
Neuroloiiical Sure. (Adv.)
Internal Medicine
Pediatrics-Primary
Medicine*
Radiology-Diag. (Adv.)
Anesthesiology (Adv.)
Urology
Anesthesiology (Adv.)
Obstetrics/G\'necology
Psychiatrv
Internal Medicine
Family Practice
Psychiatry '
Obsletrics/Gynecology
Orthopedic Surge!7
}or
Medicine*
Phy. Med/Rehab(Adv.)
Medicine-Primai7
Pediatrics
Internal Medicine
Internal Medicine
Family Practice
General Surgery
Family Practice
Anesthesiology
Internal Medicine
Pediatrics
Family Practice
Otolaryngology (Ad\. )
Surgery*
Obstetrics/Gynecology
Pediatrics
Emergency Medicine
Family Practice
Orthopedic Surgery
Obstetrics/Gynecology
Internal Medicine
Orthopedic Surgeiy /Research
General SurgeiT
Pediatrics
Internal Medicine
Lrology (.Adv.)
Internal Medicine
Family Practice
Pediatrics
Uni\ . of Kv. Medical Center. Lexington
Maine Medical Center. Portland
Johns Hopkins Hospital. Baltimore
Johns Hopkins Hospital. Baltimore
Johns Hopkins Bay\ iew Med. Ctr., Baltimore
Univ. Michigan Hospitals. Ann Arbor
Univ. Michigan Hospitals. Ann Arbor
Univ. Michigan Hospitals. Ann Arbor
iigan
Univ. Minn. Medical Scht)ol. Minneapolis
Univ. Minn. Medical School. .Minneapolis
Mayo Graduate School ol Medicine. Rochester
Boston Uni\. Medical Center
Boston Combined Peds Res. Program, Boston
Mt.Aubuni Hospital. Cambridge
New England Med. Ctr. Boston
Mass. General Hospital, Boston
Boston Uni\. School of Medicine
St. Vincents Hospital. New York
MetiX)politan Hospital Center. New York
New York Uni\ersit\ Medical Ctr.
LIniv. Rochester/Strong .Memorial. Rochester
Univ. Rochester/Strong Memorial, Rochester
Long Island Jewish Med. Ctr., New Hyde Park
New York Presbyterian Hospital, New York
St. Lukes-Roosevelt Hospital Center, New York
Carolinas Medical Center, Charlotte
Carolinas Medical Center. Chariotte
Duke Univ. Medical Ctr., Durham
UNC Hospitals, Chapel Hill
UNC Hospitals. Chapel Hill
Moses Cone Memorial Hospital. Greensboro
Mountain AHEC. AsheviUe
UNC Hospitals. Chapel Hill
UNC Hospitals, Chapel Hill
UNC Hospitals, Chapel Hill
Carolinas Medical Center, Charlotte
Carolinas Medical Center. Charlotte
Wake Forest Uni\. Baptist Med. Ctr. Winston-Salem
UNC Hospitals, Chapel Hill
UNC Hospitals. Chapel Hill
Duke Univ. Medical Ctr. Durham
UNC Hospitals, Chapel Hill /. /^.-/i-/^//;
Uni\. Hllh System East Carolina, Greenville
Carolinas Medical Center. Charlotte
Duke LIniv. Medical Ctr. Durham
UNC Hospitals, Chapel Hill
UNC Hospitals. C hapel Hill
UNC Hospitals. Chapel Hill
UNC Hospitals. Chapel Hill
UNC Hospitals. Chapel Hill
New Hainner Regional Med. Ctr. Wilmington
Wake Forest Uni\. Baptist .Med. Ctr, Winston-Salem
UNC Hospitals, Chapel Hill
Wake Forest Uni\. Baptist Med. Ctr., Winston-Salem
Carolinas Medical Center, Chariotte
20
Alycia Moore McFarland
Christopher Brent Mizelle
Christopher Brent Mi/elle
Joseph Albert Molitiemo. Jr
Joseph Albert Mohtiemo. Jr.
Jaquelin Marie Xash
Jaquelin Marie Nash
\\'end\ Gail Owen
Heather N. Roberston White
KiniberK Miehelle Rouse
Vineent Cyril Schooler
Karen B Stitzenberg
Melanie L\ nn Tew
Am\ Jacqueline Tn\ ette
John W. Watts
Jonathan Bradle\ W'otxls
Matthew Donald '"lount;
Psychiatn
Dermatology (Adv.)
Medicine*
Surgery*
Urolog) (.Ad\.)
Demiatolog\ ( .Ad\'. )
Medicine*
Medicine-Priniar)
()bstctrics/G\ necolosj
Family Practice
Internal Medicine
General Surger>
Psychiatr\
Psychiatr)
FamiK Practice
Medicine-Primary
L'rolos:\ i.Adv.J
UXC Hospitals. Chapel Hill
LNC Hospitals. Chapel Hill
Moses Cone .Memorial Hospital. Greensboro
CNC Hospitals. Chapel Hill
L'NC Hospnals. Chapel Hill
UNC Hospitals. Chapel Hill
UNC Hospitals. Chapel Hill
Duke L'ni\. Medical Ctr.. Durham
Carolinas Med:cal Center. Charlotte
New Hamner Reg. .\led. Ctr,. W'ilmnigton
Wake Forest Univ. Baptist Med. Cti . \\instoii-Salem
UNC Hospitals. Chapel Hill
LNC Hospitals. Chapel Hill
LNC Hospitals. Chapel Hill
Mountain AHHC. Ashe\ ille
Wake Forest L'niN. Baptist Med. Ctr.. W iiiston-Salem
Duke L'iii\. .Medical Ctr.. Durham
Pennsylvania
Megan Ha_\es Bair-Merritt
LaTos a A. Brow n
LaToN a .A. Brow n
Timolh\ Ward Dancy
Da\ id P. Fit/gerald
Elizabeth Leonard Fit/gerald
Corey D. Fogleman
Melinda Diane Frit/
Seth Chnstopher Collings Hawkins
Jeffrey Schiller .Meuller^
Deepa Perumallu
Douglas Da\ id Rockacy
.Amish Chandrakant Sura
Pediatrics
.•\nesthesiolog\ (Ad\. )
Transitional*
Famil> Practice
Internal Medicine
Pediatrics
Family Practice
Pediatiics
FmergencN Medicine
Transitional*
Internal Medicine
Emergence Medicine
Internal Medicine
Childrens Hospital of Philadelphia
Hospital ol the L'ni\ ol Pa.. Philadelphia
Frankford Hospital. Philadelphia
UPMC Shads side. Pittsburgh
Hospital ol the Linn. ol'Pa.'^ Philadelphia
Childrens Hospital of Philadelphia
Lancaster General Hospital. L,ancaster
Llni\. Health Center of Pittsburgh
Lini\ . Health Center of Pittsburgh
L!ni\. Health Center of Pittsburgh
Hospital of the Univ. of Pa.. Philadelphia
L'ni\. Health Center of Pittsburgh
L'ni\. Health Center of Pittsburgh
South Carolina
Tro\ .Augustus Bunting
Bamab\ Todd Dedmond
Zane Ian Lapinskes
Internal Medicine
Orthopedic Surgen.
FamiK Practice
Medical Uni\ . of SC. Charleston
Palmetto Richland Mem. Hiispital. Columbia
Self Memorial Hospital. Greenwood
Tennessee
Michael Thomas Capps
Seth Monis Cohen
Peter Howard McHu'jh
Medicine-Pediatrics
Otolaryngology (Adv.)
Medicine-Pediatrics
Vandcrbilt Uni\. Medical Ctr.. Nash\ ille
Vaiidcrbill Univ. Medical Ctr.. Nashxille
L'nn. Tennessee COM. Memphis
Texas
Janet Eli/abelh Hams
Dawn Denise Johnson
Jason Neil Kat/
Susan Lee Marcelli
Tans a Pauline Tiamfook
Obstetrics/G\ nccolog;
Pediatrics
Emergency Medicine
Obstetrics/G_\ nccolog;
FamiK Practice
Univ. Texas Med. School. Houston
Uni\. Texas Southwestern Med. Schiiol. Dal
L'ni\. Texas Southwestern Med. School. Dal
Baylor College of Medicine. Houston
Uni\. Tc\as Med. Branch, (iabcston
Robert Stuart B\rum
Chris D Fennelf
Erie hars Franckc
Traces Louise Huckabec
MokhtarO. .Morgan
Scott Da\ id .Nash
Michael Karim Newman
Stephen Andrew Oljcski
Jonathan R Saluta
Yalaunda .Michelle Ihoma'
James Eric Turner
R\an Carl Wanamaker
\\usliin)it<)n
.Neil C \ iniHL'
Internal Medicine
.Anesthesiology
Orthopedic Surg.-fith M-ar
FamiK Practice
FamiK Practice
Medicine-Pediatrics
Plastic Surgery*
Transitional*
Orthopedic Surgen
Surger\ *
Internal Medicine
Medicine-Primary
Oilhopcdic Surgery
Liniversity of Virginia. Charlottcs\illc
L'ni\ersit\ of Virginia. Charlottesv ille
I 'ni\ersity of Virginia. Charlollcs\ ille
Chippenham Medical Center. Richmond
Rixcrsidc Regional Med. Ctr. Newport News
Medical College of Virginia. Richmond
Medical College of Virginia. Richmond
Carilion Health S\stem. Roanoke
Mctlical College of Virginia. Richmond
Uni\ersiiy of Virginia. Charlottes\ illc
L'ni\ersiiy of Virginia. Charlottes\ille
L'ni\ersii\ of Virginia. Charlottes\ille
Madi'jan Arniv Medical Center. Tacoma
Alumni
Notes
50s
William S. Jovner, MI) "50. recently
mo\ed to the nevvlv opened Croasdaile
Methodist Retirement Community in
Durham, and writes that he and wife
Jane are doing their best to keep the
UNC Hag flying in the shadows of the
Duke campus.
Dan A. Martin, MI) "50, is still engaged
in his work as director of Trover Clinic
Foundation Education Division and as
medical director of the Hopkins County
(Kentucky) Health Department. Martin
can be reached at kymartinsC? \ci.nct.
John L. McCain, MD "50. is the medical
director of three nursing homes, in addi-
tion to his practice in rheumatology and
geriatrics. McCain writes that he is enjoy-
ing his practice a great deal — he went
solo in "92. moved into a new office in
"98. and became a certified medical
director in "98. McCain and wife Betty
li\e in Wilson. NC.
IJoyd C. McCaskill, MD "55. joined his
cousin. Norman McCaskill. along with
their wises and families last April in the
dedication of the UNC-CH McCaskill
Soccer Center by the UNC Athletic
Department and the Educational Founda-
tion. McCaskill's family of UNC gradu-
ates includes Norman McCaskill. "33:
Lloyd C. McCaskill. '51 and "55; L.
Curtis McCaskill. Jr. "78: Donna Jordan
McCaskill. "TS: T. Gray McCaskill, "79;
Kimberly Davis McCaskill. "80: Janell
McCaskill Hannah. "83: Roger D.
Hannah, "79: and future graduate James
Curtis McCaskill. Lloyd"s grandson, a
sophomore.
60s
emerald (Jerry) Fernald, MD "60.
remains acti\e in resident recruitins: for
the department (if pediatrics and the F.W.
Denny Society at UNC.
Frank McCain, MD "60. has two part-
ners now after 35 years of solo allerg\
practice. McCain works 4 days each
week and says that he is enjoying his
work more than ever, because having the
partners affords him more time with his
patients and less stress.
G. Thomas Strickland, MD "60. says
he has no plans to retire anytime soon —
he still enjoys teaching medical and
graduate students, house officers and
health care pro\ iders in practice.
Strickland has research projects ongoing
in Mar\land, Brazil, the Philippines
and Egypt. He and wife Anne li\e in
Baltimore, and can be reached at
tstrickland@som.umar\ land.edu.
Robert L. (Jrubb, Jr., \ID "65. is heavi-
ly involved in bitth clinical neurosurgery
at Washington University in St. Louis and
in research using PET scanning to
patients with severe head injuries.
Grubb's wife, Julia, is vice-president of
the Friends of St. Louis Children's Hos-
pital and serves on the board of directors
of Epworth Children's Home in St. Louis.
His son. Robert III. is a fourth-year urol-
og\ resident at Barnes-Jewish Hospital,
and daughter Mary Connell is a first-sear
law student.
Robert Kindley, MD "65. retired from
the .Air Force m 1996. after 22 years.
Kindley is now in private allergy practice
in the Destin-Ft. Walton Beach area of
Florida. He and w ile Lynn can be reached
at rkindle\'(?' aol.com.
WIMiam F. Savers, MD "65. retired in
January of this year. He and wife Bett\
arc looking forward to spending more
time at Bald Head Island. NC. and
Iraseling. They can be reached at
wsayers(n triadiT.com.
F. Walton .\very, MD "67. retired from
pathology practice in July "99, and
recently returned from a vacation in
Israel — a trip that he says is a must for
e\er\one.
70s
Stephen L. Green, MI) "70. has started a
charils called Sedona LTD. dedicated to
bringing AIDS care to the Caribbean and
Central .America.
John F. Hanna, MD '70. retired from
otfice urologs practice in Louisburg. NC .
in 199S and mo\ed to Sarasota. Fla.
Hanna writes that he is doing real estate
and property management in a hot mar-
ket, and doing better than ever in medi-
cine, w iih a lot less stress.
Bruce Berlow, MD "75. moved to
Mystic. Conn., two years ago after prac-
ticing in Santa Barbara. Ca. for 18 years.
He and w ife Lee can be reached at
bbcrlow (n pol.nel.
Frank Moretz, MD "75. is currently the
secretary treasurer for the N.C. Society of
.Anesthesiologists. Moretz is slated to be
president of the NCSQA in 2002.
F;d Morris, MD "75. received a PhD in
philosophy in 1998. and is currently
leaching philosophy part-time. Morris
enjoys running, and has completed six
marathons, including two Boston
Marathons.
Cynthia D. Conrad, MD "78. has a new
position vsith Connecticut Valles Hospital
(the state's long-term psychiatric hospi-
tal) as Chief of Professional Ser\ices.
She has spent the past 13 \ears associated
with the Institute ot Li\in>; in Hartlord.
80s
Lawrence Wyner. MD '83. is a leiial
transplant surgeon at Chariestt>n Area
Medical Center in West Virginia. He and
his wife. Louida. announce the birth ol
their second child. Tessa Anneliese. u ho
was horn No\. 30. 1999. Their son. Joshua
Ross, celebrated his third birthda\ in Jul\.
Sebastian R. .Alston, MD '85. is cunent
ly an associate protessor ot patholog} at
Mercer Uni\ersity School of Medicine in
Macon. Ga. Alston says he is having a lot
of fun at Mercer, and he currentl\ serves
as secretary of the Group for Research in
Pathology Education (GRIPE), the pathol-
ogy education association.
Leslie .\. Bunce, .MI) '85. reports that
alter nine years in academic hematolog\/
\ascular medicine at the Uni\ersity of
Rochester and two and a half \ ears in
pharmaceutical medicine in Research
Triangle Park. .NC. she recently began
an open-ended hiatus to enjo\ time at
home with her two sons. Michael. 6.
and .lames. 4,
Elizabeth Kngelhardt .Mandell. .MD '85.
her husband. Jim. and children Michael.
6. and Kaitlyn. 3. recently mo\ed to the
Minneapolis/St. Paul area in order to be
closer to Jim's job as a pilot for .Northwest
Airlines. Mandell is currently interview-
ing for jobs and plans to continue her
practice in occupational medicine,
Terrence (Sonny) .M(irt(in, MD '85. is
currenti) practicing coiiimumt_\ hospital
emergcncN medicine, and expects to com-
plete a dual .MBA / MHA degree program
next spring.
active with a group of pediatricians from
her hospital who volunteer their serv ices
to children in El Salvador. Thomas says
she finds the work very rewarding, and
recommends physician volunteerism to
aiivone suffering from "phvsician hurn-
Marilyn Russell, PhD '86. is an adjunct
pritfessor of biologv at Gonzaga Universi-
tv. in Spokane. Wash. Russell says she
enjov s raising her granddaughter. Angela,
renovating her farmhouse and l.^-acre
farm, and raising organic vegetables m
her greenhouse year-round.
Michael Duggan, MD '88. and his w ife.
[-aura, lecentlv celebrated the birth of
their second son. Luis Raphael. Their
son Max Perez is 6 years old. Duggan is
a pathologist w ith Pathology Medical
Services in Lincoln. Neb.
Philip Thwing, MD '88. is proud to
announce his engagement to LcAnne
Keicher The two were to be married in
Julv. His email address is:
PhilThwinu a Greene. \tn. net.
90s
lodd Cowdery, MD 'y(». lues and works
in the San Juan Islands of Washington
State on an island called Orcas. Cowdery
serves the communilv as a familv phvsi-
cian. He reports that Orcas is roughlv the
si/e of Manhattan, but with only 1/1 OOO'*^
the population. A critical difference, he
notes, to he and his two partners who pro-
vide the island's onh 24/7 medical care.
Cowderv relies on the consiaiu compan-
ionship of his dog. Jericho, whom he
calls a dog with a remarkable travel (ale.
Cowderv can be reached at:
tcovi,derv (" rockiskuufcom.
a PhD from Medical College of Virginia
in 1998. He is current! v in a cardiotho-
racic surgerv fellow ship at Hahnemann
Universilv Hospital m Pennsv Ivaiiia.
Gary M. Myles, PhD '90. graduated liom
law school at the Universitv of Washing-
ton in June "99. Myles is now an associate
patent attomev at Seed Intellectual Prop-
erty Law Group PLLC. a chemical/
hiotechnologv practice in Seattle.
Todd (Jriffith. MD '97. has begun a
nephrology fellow ship at Duke L'niversiiv
Medical Center Griffith, his wife. .Andie.
and their two children are excited to be
returning to the Triangle. Thev can be
reached at :todd.i:ri filth Cp alumm.diike.edu.
Deaths
.k'rr> F. Kriigh, MS. PT '84
Claudia Ihomas. Ml) '85.
.urrenllv
.John ( Iriv I Liit«istle. Ml) '9(» uceived
23
Development
Notes
Loyalty Fund Campaign
Rciininn aiul ivfiioiuil committee chairs presented more than $S22.()Ol) in
Loxaltx Fund donations at the Sprint; Medical Alumni Banquet in
Chapel Hill. Final aunpaign totals for the year ending June 30. 2000
are listed helow.
Number of
Percent
Total Cash
Class/Region
Volunteers
Participation
& Pledges
Class of 1945
3
16/24(67%)
S 6.8(X)
Class of 1950
11
32/39(82%)
$ 20,000
Class of 1955*
23
44/48 (92<7r)
$150,500
Class of 1960
24
35/60(59%)
$ 40.000
Class of 1965
12
24/54(44%)
$ 14.000
Class of 1970
12
31/69(45%)
$ 30.000
Class of 1975
TT
34/100(34%)
$ 168.500
Class of 19S()
10
50/153(33%)
$ 19.000
Class of 1985
15
37/143(26%)
S 24.000
Class of 1990
24
45/125(36%)
S 13.500
Class of 2(X)0*
20
1 16/13()(89%)(,n,./,U,n/v
S 25.525
Atlanta***
10
43/108(40%)
S 14.000
BLincoiiihe***
.\shcyille
Durham/Orang
12
29/67(43%)
$ 16,500
e 18
124/343(36%)
S 63.500
Forsyth
21
51/100(51%)
$ 33.(X)0
W'inston-Salenr
Guilfoi'd
Lheenshoro
Mecklenburg
28
103/174(59%)
$ 49.500
25
86/217(40%)
$ 60.000
Charlotte
New Hanoser
14
41/70(59%)
S 35.200
Wilnungton
Wake
25
106/276(38%)
S 39.300
Raleigh
'irpn'Hiil'. /i(i,'/iCA
level i>t iiliinini piu
tieipcititinin elci.'.s.
**Foiirth-yciir CiiiniHiiiiii reuclied all-
time hii:h ii/z/i S9'", purlieipiHidn.
* * *Ccisli only, iwl including pledges
Hatcher Golf Tournament
scheduled
The 2000 Mike Hatcher Memorial Golf
Tournament kicks off w iih registration at 1 1 :30
am. on Monday. Oct. 9. at Prestonwiiod Golf
and Country Club in Cary.
The shotgun start will he at I p.m. Cost is
S 1 50 per golfer, w hich includes a charitable
contribution of S65.
The tournament raises money for cystic fi-
brosis research at UNC. Since the e\ent started
four years ago. it has raised more than
$200,000. Last year, there were appro.ximately
300 entrants.
To enter, contact Greg Hatcher, tournament
director, at (919) 469-3868 or 310-9758
( pager) or email ghatcher(5' ix.netcom.com.
Or. contact Jim Miller at The Medical
Foundation of North Carolina. Inc. at (919)
966-1201 oremailjim_miller(? unc.edu.
Honor Roll of Donors . '
Correction
The Winter 1999/2000 issue of the Bulletin
included the Medical Foundation's annual
"Report to Donors." which features an Honor
Roll of Donors who made contributions to the
Loyalty Fund during the preceding fiscal year.
L'nfonunately. not all names were included in
the Loyalty Fund List. Our apologies to those
donors v\ hose names appear below :
• J.AllenWhitaker.M.D. "31
Rocky Mount. NC
• JackB.Hobson.M.D. "57
Charlotte. NC
• Robert S.Cline.M.D. "57
Sanford. NC
• Robert J. Cowan. M.D. "63
Winston-Salem. NC
24
President's
Letter
As I dro\e to Chapel Hill in Ma\ lo
piirticipate in the graduation cero-
nion\ tor the Sehool of Medi-
cine's Class ot 2()()(). I was
alread) excited about m\ being inxited to
participate.
Just 16 \ears bexond ni\ own gradua-
tion in that same Memorial Hall, the memo-
ries ot" it all remained \ i\ id. The e\ ent
marked one otlhe tlnal academic milestones.
w ith the presence ot Tamily and close friends
adding due weight lo the occasion. It was at
once a celebration and a good-bye to class-
mates before scattering hither and yon. With
an idea of w hat lay ahead for this year's class.
1 shared the electricity of the eager graduates.
.As Dean Smith said in his often-imitated un-
emotional nasal twang amid the immediate
aftermath of the UW2 championship. "I am
happy for our seniors." (The next year, you
recall. Jim VaKano demonstrated how to cel-
ebrate as he spun around the court in Brow n-
ian motion!)
Anyway, as it turned out. graduation day
this time around was notable more for the
time Just before the ceremony. Having re-
ceived by mail my parking placard, my mind
was free as I cruised into tow n vv ith about
30 minutes to spare. From a radius of a mile
or so. I started to see cars double-parked on
the major thoroughfares. Closer to campus,
centripetall-obese fathers, red-faced and
soaked with sweat, were struggling uphill
along the sidewalks as their perky gow ned
daughters set the pace. Closer still, the
swarms of humanity required me to slow
down to walking speed, (inally I approached
the Columbia .Street-Cameron A\enue inter-
section where the hallowed path to the Old
Well was blocked. A barricade was manned
by three people, including an armed police
officer, but a simple wa\e of my parking
placard got for me a smile and a welcome
through.
As I inched toward Memorial Hall, gently
easing my way through groups of people
standing on the pa\ement. it was plainly ap-
parent that I was one of the \ery lew allowed
to pass that way. Moments later.
GniUtiidc
Tlw liii;li pri:f of lite, ilic ndwiiiiii; tcrtiiin
(>l (I mail, is u> he horn with a hias u> sonic
pitisnit which finJ.'i him In employment
iiihl luippincss.
Ralph W'alilo F.mcison
I parked within .SO teet of the aLidiloiium
where, incidentally, there \\ere another
15 empty spaces. Without question, that was
the highlight of my Tar Heel career
Other e\ ents come to mind — getting an
.A in organic chemistry, being oflered a seal
in medical school. e\en getting midcourt
bleacher seats in Carmichael tt)r the Caroli-
na-Duke game — but none of these approach
the ie\el of my special parking pri\ilege as
president iif the UNC Medical Alumni
Association.
For the parking space and for the eight
wonderful years at Carolina, I am deeply
grateful. Having received a top-le\el educa-
tion at nominal cost. UNC deserves my life-
long loyalty and support. Since each of you
shares w iih me this legacy of pri\ ilege. I urge
you to join me in meeting our responsibilit\
to give something back lo our alma mater.
Refer your patients. Connect w ith your fel-
low alumni at the various social functions
and CME"s. Precept a student. Become a
Loyalty Fund associate. Look for wa\s to
build up our School of Medicine as so maiiv
before us havetlone proudly.
CME/Alumni Calendar
September 15-17. 2000 - Kingston Plantation. Myrtle Beach. SC
N.C. Society of Anesthesiologists Fall Session
September 16. 2000 - Chapel Hill
Family Day / While Coat Ceremony
September 22-23, 2000 - Chapel Hill
I'NC Wound Management Conference
September 2S-30. 2000 - Chapel Hill
Ross Society Annual Meeting
October 3. 2000 - Chapel Hill
Dedication of Neuroscience Research Center
October 6-7. 2000 - Durham
UNC Children's Burn Conterence
October 10. 2000 - Chapel Hill
Berryhill Lecture
October 13-14. 2000 - Greensboro
UNC-Duke Women's Cancer Conference
October 20-21. 2000 - Chapel Hill
Fall Medical Alumni Weekend
For more information about CME courses, contact the Office of
Continuing Medical Education at (919) 962-21 IS or toll-free
through the Consultation Center at (800) 852-6264. To contact
the Alumni Affairs Office, call (919) 962-6786 or email
medical alumni Cp nied.unc.edu
m'^^'M
Estate Planning Notice
Many individuals would like to make a major gift
to the UNC medical center, but cannot commit
current assets for such a purpose. Through a will,
however, anyone can make a more significant gift
than they might ever have thought possible by
designating a specific sum, a percentage, or the
residue of their estate for the benefit of the medical
To provide a bequest, simply include a paragraph
in your will naming The Medical Foundation of
North CaroUna, Inc. as a beneficiary. For example:
"I give, devise and bequeath (the sum of$
or ( % of my estate) or (the residue of
my estate) to The Medical Foundation of North
Carolina, Inc., a 501(C)(3) created to maintain
funds for the UNC medical center with principal
offices located at 880 Airport Road, Chapel Hill,
North Carolina."
This language creates an unrestricted bequest for
use by the medical center when and where the need
is greatest, or you may specify that your gift be
used for a particular purpose.
For further information on bequests, contact
Jane McNeer at (919) 966-1201, (800) 962-2543,
orjmcneer@email.unc.edu.
Medical Alumni
BUiXETIN
School of Medidne, Unhnersi^ of North Carolina at Chapel Hill
rancis Collins, MD 77
Guides Effort That Is
Changing Medicine
Dean's
Page
state of the School 2000
Rcceiitl). in iiiv annual ""stale ol the
School of Medicine" presentation to lacuitN
and staff. I described the many w a\ s UNC is
setliny a new standard of excellence in
teaching, lesearch and patient care.
We are wiirking to undergird our educa-
tional mission with three major thrusts: Fo-
cusing know ledgeable faculty leadership,
developing leading-edge facilities and de-
ploying outstanding program de\elopment.
We"\e made tremendous strides in each ol
these areas, and I wanted [o share that infor-
mation w ith Nciu. our alumni and friends.
Leadership: I have often referred to 2000
as ""the year of recruiting chairs ' The
.School of Medicine recruited eight new lac-
ully chairs this year. Since I joined the
schot)! in l*-)97. vve"ve recruited a total of 14
new chairs, four new center directors and
two new center co-directors.
Many of these faculty leaders studied or
trained at Carolina, and consider their return
to he a homecoming of sorts. Others were at-
tractetl by the appeal of living in the Town
on the Hill and by Cart>lina"s international
reputation lor high-e|Liality education and
clinical care. All of them come with
impressive academic credentials and prmen
track records of exceptional program
de\elopment.
Please join me in welcoming our most re-
cent new department chairs. The\ are: V\ tas
Bankaitis. PhD. cell biology and anatomx ;
Luis Diaz. MI), dermatology; Frank Fongo.
MD. PhD. Neurology. Terry Magnuson.
PhD. genetics: Lee McLean, PhD. allied
health: Travis Meredith. MD. ophthalmolo-
gy: Marschall Runge. MD. PhD. medicine:
and .-Xlan Stiles. MD. pediatries.
The Medical Alumni Biillviin has |nih-
lished profiles on some of these facult\
chairs alreatl\. aiul will continue to intro-
duce you to others in upcoming issues.
Facilities: .-\n\one w ho has spent time in
the School of Medicine's educational or re-
search buildings knows the amount and
quality of space lea\es something to be de-
sired. But. several positive improvements
are under vva\ .
First, the Neurcseiences Research Build-
ing is expected to open this spring. The
eight-story. .$30-million facility will hi>usc
the L'NC Neuroscience Center, where re-
searchers will study issues related to the
brain, including how the brain develops and
how it responds to damage. The building
also will prov ide permanent space for the
neurobiology curriculum and adtlitional
space for several new facultv members in
basic neuroscience.
Other occupants include the School of
Medicine's animal-models center and its
"mousers." researchers who study mouse
genomics. Research components of the de-
partments of ophthalmology and neurology
also vv ill move into the new facility.
Construction on the Medical Biotnolecu-
lar Research Building is under way. as well.
This lOO.OOO-square-foot. $64-million fa-
cility will house 60 to SO principal inv estiga-
lors. and prov ide two auditoriums, one
seating about 500 people, the other .^00.
Voter enilorsement of the Nov. 7 bond ref-
erendum means the School of Medicine will
receive nearlv S.'^O million to finish the
Medical Biomolecular Research Building.
The boiuls also will provide another $60
million to make desperately needed renova-
tions and improvements to the Medical Sci-
ence Research Building, the Burnett-
Womack Building. Beiryhill Hall and other
facilities.
Pntjjram development: We have plans
to grow om genomics, vascular biology,
bioinlormatics and infectious disease pro-
grams. Vascular biology will get four new
faculty positions, while infectious disease
has alreadv recruited faculty for two new po-
sitions.
The Department of Genetics, under the
direction of Dr. Magnuson. will receive 10
tenure-track faculty positions from the
School of .Medicine. Last year, the program
received S2.6 million over four \ears from
the How ard Hughes Medical Institute to
help establish genomics core technologies,
including a chromosome imaging facility.
The HHMI money also w ill help recruit four
junior faculty members by offering start-up
packages for equipping their laboratories
and prov iding support for technical person-
nel and supplies. In addition, there w ill bean
another 16 facultv positions funded by the
L'niversity in various other programs across
the campus.
In bioinlormatics. four new faculty posi-
tions have been allocated and I've granted
"licenses to hunt" to build programs in kej
areas. Reflective of our effort to meld clini-
cal expertise with bioinlormatics knowl-
edge, the School of Medicine was ju"Sl
awarded a contract by the Cystic Fibrosis
Foundation Therapeutics. Inc.. an affiliate ol
the Cv Stic Fibrosis Foundation, to create anc
maintain the nation's first comprehensivj
bioinlormatics center for cv stic fibrosis re-
searchers.
Recruiting more researchers continues tc
be one of my piiorities. and the faculty of th(
School of Medicine have supported me bj
allowing me to withhold 1 percent of al
state dollars for the purpose of creating new
positions. By 2001. this withhold will b<
worth SI. 6 million — all of which will b<
used to partiallv support up to 40 new faeul
t_v positions.
The School of Medicine is an organiza
tion full of exciting new initiatives led by
dedicated and motivated faculty and staff
who are committed to excellence and who
have great expectations for tomomnv .
Future Dean's Page columns will focus
on other elements relating to the "'State of
the School of Medicine." Nc.xi: Re-shaping
the curriculum and what we're doing to
address other educational issues.
mn
L
i-tu^t
JctfirxLHiniin.MD
Dean. ScluKil ofMcdiiinc
0;
-—
.-.-- --
' DEC
HE.KLTH SCi
T
Medical Alumni
Association Officers
President
Paul E. Viser. MD '84
Clinton
President-Elect
Thomas J. Koonlz. MD '66
W'inston-Sdicni
\ ice President
Ray M. Ha\ worth. MD "62
Kno.uille. Tn
Secretary
JohiiM. Hcrion. MD"83
\Vilniini;t(>n
Treasurer
WilhamM. Herndon. Jr.. MD'Sl
Charlotte
Editorial Staff
John \\. Stokes
Vice President. Public Affctirs
& Xfcirketiiiii
Debra Pierce
Editor
Michele Ble\ ins, Bernadette Giilis.
Catherine House. Leshe H. Lang.
Katie .Macdonald. L\nn W'ooten
Conlrihuli/ii^ Writers
Dan Crawford (pg. 20)
Steve Exxum (p<z. ?<)
Jay Magnum (pg. 11. 14. \5. IX. 24i
Will Ouens (pg^ 2..^)
Photo\ir(ipher\
llic Miiin iilMiiinni Hiillcliii is published tour times
annuiillv h> ihefNC-C'hapc-l Hill Mcdic;il Aliinirii
Asviciatiiin. C'hiipol Hill. .\C 27.^ 14. P(islai;e IS p.ml
h\ ihc min-protil a^s()l.■lalllln ihrouyh L'.S. Postal
Pcrmil No. 24. .Address correspondence to the editor.
Office olMedical Center Public .Mfairs, School ol
Medicine, CB#7WK). I nixersitv or North Carolina,
Chapel Hill. NC27,S 14
Medical Alumni
BULLETIN
School of Medicine, University of North CaroHna at Chapel Hill
Contents
Features
With Scientific higenuits and a Little Lucis, L'NC Physicians Help Couples
Concei\e Babies 2
Women's and Children's Hospitals Will Be the Newest Additions to the UNC
Health Care Famih 4
,Muiiiiii Profile: .Alphabet Soup
LW'Ciiliini tiiincis Ccllins SeiTes Upthe Huimin Genome 'Recipe' and Sets ilie
,S7(/.t,'c FcrA Mind-Biii:i;linii Medical Revolution 6
Health .Al'tairs Bookstore Has A New Home 9
Dean's Choice Ill
Family Day 2000 14
Faculty Profile: Marschall Range, .MD. Chair. Department otMedicine I S
Scholarship Established In Honor of Harold Roberts. MD 20
UNC Protessor Endow s National Prize In Neumscienee 2 1
2000-2001 Loyalty Fund Scholars 26
Lo\alty Fund Campaign 2S
Report to Donors 29
Departments
Dean's Puge Inside FionlCtner
News Briefs 12
Faculty Notes 16
Research Notes 22
Developtneni Notes 24
.Aluinni Notes 25
Piesidcnl's Letter Inside Back Ciner
CME/Alumni Calendar Back Co\er
(hillh Cinii: .MicT 10 lonj; scaisol pivp.ir.iUon Ir.iiK is( 'olliiis. .\1I) 77 ,iiul the icsc.uch
stall at the NatKinal Human (lenomc Research Itistitiiic alony w ith scientists wnrkiiii:
together at laboratories around the world cracked the hiuuan body's jicnetic code, an
astoundin': feat thai promises lochanj;c medicine loiever Photos fnim the,! line 2{KH1
newsconterence held at the White House ,irc couilcs\ ol ihc N.ilional institutes ol Health.
With Scientific Ingei
UNC Physicians Helj
By Catherine House
Late one night, Stan
Beyler, MD arrived at
the airpoil alter a busi-
ness trip and boarded
a shuttle to his ear. It wasn't
erowded. so Beyler notieed that
a niuseular man dressed in
leather and seated at the baek of
the bus was staring at him. It
made Beyler uneasy.
Suddenly the man in leather
blurted out. "Hey! You're ihi
man who got my w i K
pregnant."
Antieipating trouble, ilu
other passengers braeed them-
sehes against their seats, but
Beyler ealmly replied, "Oh ^''^'<''' ""''
sure. I remember you. How are
you doing?"
As it happens. Beyler was only doing his
job. As a seientist at UNC Hospitals
.Assisted Reproduetive Teehnologies (ART)
pntgram, Beyler works with t'eilility speeialists
to help eouples eoneei\ e.
Despite the \ast number ol unintended
pregnaneies eaeh year in the United States —
about three million, aeeording to the Alan
Guttmaeher Institute — getting pregnant ean
sometimes be extraordinarily diffieult. As
many as 10 million Ameriean couples are
infertile, and some spend years trying to
conceive, often without success.
In vitro fertilization (IVF) — commonly
know n as "test tube" pregnancy — has
helped many couples achie\e their dream of
lia\ ing a child. Since m7S, there ha\e been
moixMhan 30().()()() successful IVFs world-
u ide. .At UNC Hospitals, about 125 couples
undergo IVF each year. About
40 percent become pregnant and some 30
percent end up with a live biilh.
While that rate may seem low. Be\ ler.
clinical assistant professor of obstetrics and
gynecology and director of the clinical
androloev and embrvoloi;\ laboratory.
Ills cliiUlrcii Piiiil (iiul Bcckx. wife Marxhah aiul cut Mil,
explained that it is similar to "natural"
conception rates. Even with no fertilitv
problems and no contraceptive use. only one
in three reproductive cycles result in successful
pregnancy.
Also. Beyler explained. IVF is onl\
successful w hen both piirties have functioning
gametes — that is. eggs or sperm. If a
woman's egg quality is poor, then an egg
donor is a possible alternative. Older women,
for example, may be able to carry a child, but
their eggs might be "worn out." A woman is
bom with all the eggs she will ever have —
about two million — but by the time she
reaches puberty, there may be only about
400.000 left. By the time she turns 40. there
may be \ cry few good qualitv eggs left.
If a man isn't able to produce spemi. then
the only option is to use donor sperm. But
e\ en if a man has a low count. Beyler said,
pregnancy is possible. Sometimes the spenn
just needs a little help reaching its destination.
E\ en when a man has a normal sperm
count, less than I percent of the spemi present
in the ejaculate actually make it into the
woman's uterus, and fewer still make it to
fertilization site in the fallopian tube. In this
case, Beyler can use a proce-
dure called interuterine in-
semination in which the
man's spenn is taken directly
futm his testicles and inject-
ed into the woman's uterus
w hen she's ovulating. But
that doesn't guarantee
fertilization.
Michael GO' Rand. MD,
professor of cell biology and
anatomy and one of the
founders of UNC's IVF pro-
gram, studies sperm-egg in-
teraction. To understand the
process, consider the design
of a human egg. Eaeh egg has
a shell around it, called a
zona pellucida, that protects
the egg, provides a secure
place for the embryo to grow
and keeps extra sperm from
getting in. First, the sperm has to penetrate
the shell, and then it has to fuse with the egg.
In each of these steps, certain proteins in
the spemi are insohed.
"If a man is infertile, one or more of those
proteins may be missing or nonfunctional."
O'Rand said. "We're trying to understand the
basic biology of each of those steps —
figure out which proteins are needed for
w hich step."
While this work e\entually may help re-
searchei's restore function to defective sperm
by adding new proteins. O'Rand siiid "micro-
manipulation" techniques — recent procedures
designed to facilitate the fertilization process
— often b\ pass the protein problem. But if
doctors somedav could tell w hether sperm is
defective beforehand, they'd know which
techniques would work. sa\ ing time and ex-
pense.
Beyler said that w hen he started pert'omiing
IVF in 1987, it was just a matter of finding
the eggs in fluids sent to his lab and putting
them into culture. Then the right number of
w ashed spemi w ere added, and he would let
nature take its course. But since those "early
iity and a Little Luck,
I!ouples Conceive Babies
Liiiini ct Chi\ Hiillduay with daui^htcis
Lnuixn and Eiiiilx
da\s."" a number of techniques ha\e e\()l\ed
to help int'enile couples.
The first technique used was partial-zonal
drillms:. which in\ol\cs (ipening up little
holes around the egg. The idea is that by
opening up the shell a little bit. weaker spemi
can gel in to Icrtili/e the egg. Sub/onal inser-
tion went a step further: A teu sperm are
phssically placed in the layer between the
egg membrane and the shell, in hopes that
one will penetrate the egg. This procedure
doesn"t always work, though, because the
sperm often just end up swimming around in
the fluid between the shell and the mem-
brane.
Fmallv. there's mlrac> loplasniic sperm
inieclmn ( ICSI). in which the spc-mi is injected
direcll\ into the inside of the egg. Beslersaid
It's important to avoid damaging the egg
nucleus w ith this priK-edure.
"There are a lew tricks imohetl to make it
work well." he said, "l Inst kill the sperm
ph>sicall> h\ breaking iis neck with the
injection pipet. draw u|i its tail and then
quickls enter the egg cstoplasm. After that. I
suck back some egg cstoplasm to make sure
I'm through the membrane and lo allow ihe
sperm lo mi\ with the egg cytoplasm. 1 then
inject the sperm and c\ toplasm mixture back
into the egg."
To help improve IVF success. Beyler and
his colleagues began seeing patients in c> cles
rather than continuous!). That wa\. he sa\ s,
they can work w ith several patients at one
lime, perform IVF for them, step back and
analyze the results.
For instance, they're trying to make the
cultures in test tubes more like fluid in the
fallopian tube at mid-cycle. For IVF. embry-
ologists used to use a nonspecific culture
medium — the same kind used for experi-
ments such as growing cancer cells.
"But there were a lot of extraneous nutri-
ents that weren't vital lo fertilization and
might even be detrimental to earh iirowth."
Beyler said.
During the middle of a woman's cycle, for
example, there isn't much glucose or phos-
phate found in the fallopian tubes, but both of
these nutrients were in the original media.
Beyler found that eliminating some of the
glucose and phosphate appeared to improve
pregnancy rates.
"It's a lot of trial and error." Bevler said.
".Sometimes it's a matter of prescribing dif-
lerent combinations of homione medications
or tr\ ing a new piece of equipment."
A tew years ago. there was an unusuallv
high rate (about .^0 percent) of multiple
pregnancies. Techniques had improved for
stimulating egg growth, for getting more
eggs to lenilize and for better culture condi-
tions. To compensate. Beyler and his
colleagues tried waiting three to five davs
instead of two days to transfer embiyos to the
woman's uterus. This was. doctors can pick
out the strongest ones and transfer fewer.
Bevler said mulliple-pregnancv rates have
come down lo 2(1 peiceni. mosi ot which are
twin pregnancies.
.Another helpful technique is crvopreser-
valion - lieezing eggs, sperm, or embryos -
which allows more chances at fertilization
with frozen sperm, or the transfer of thaw eti
embrvos to ihe ulerus. Irom one sperm
biopsy, for instance. Bevler can separate the
sperm into small quantities and freeze the
portions he doesn't use.
"I onlv need a few thousand sperm to w ork
w ith." Beyler said, "and typically even a
small count has a few hundred thousand
around."
In line case. Bev ler combined IVI- and
cr\ opreserv ation. A cancer patient decided to
hav e some of his sperm frozen before under-
going cancer treatment since chemotherapy
tends to reduce spenn count. Ftir 1 9 \ ears, his
sperm were kept in UNC's sperm bank.
About a year ago. the patient and his wife
decided they w anted to have children. Be\ ler
thawed Ihe patient's sperm and performed
ICSI to lertilize his w ife's eggs. While she
didn't conceive on the first attempt, the lab
still has plenty of sperm.
"The sperm seemed to be line." Bevler
said. "We think the problem might have been
a female factor, so if we can tlgure out how to
get better eggs from the woman, then we can
tr\ again." D
I This arricic appcuis in liic I'nil 2(HH) issue
('/'Endeavors iihi\:(i:inc und is irpiiuiccl with
permission. )
t.rsscr. wife IUiilhii,i i
Women's and Childrei
Newest Additions to the
Construction of the new N.C.
Women's and Children's hospi-
tals has been hampered by
numerous factors, including:
• A deluge of rain in 1998 that caused a
4()-day delay;
• Changes made to the original design as
well as changes required by the builder,
and
• Unexpected glitches, such as the required
removal of more rock from beneath the
construction site than was first predicted.
As soon as construction is complete, work
begins on the renovation and expansion of
the lobby in the main hospitals building. That
reconfiguration will connect an improved
lobby and expanded outpatient pharmacs
area with a two-story, glass concourse run-
ning the breadth of the entire medical center
complex — allowing patients, visitors
and stall to easily mcne from one building to
another.
To learn more about the new hospitals and
to see artist's renderings of patient rooms,
lobby and nurses station as well as construc-
tion photos, \'isit www.unclwalthcare.org
Facts about the
N.C. Children's Hospital
•The all-pri\ate patient rooms are
designed to feel as much like "home" as
possible. They feature private bath
rooms with tubs and showers; laminated
walls so children can display artwork, get-
well cards and photographs; and conveil-
ible sofas to accommodate relatives
spending the night.
• UNC offers the state's only accredited
Hospital School for children in K-12 with
teachers and a full-time principal to help
children keep up with their classroom
studies during their hospital stays.
' Pediatric care at UNC was ranked 22nd
nationally by U.S. News & World Report
magazine in its annual "Best Hospitals"
ranking.
' The N.C. Children's Hospital will offer
"one stop health care" for children and
their families: all pediatric clinics will be
housed under the same roof, and feature
kid-specific and kid-friendly operating
and pnicetlure rooms.
' The hospital will offer interactive enter-
tainment for children. One will be an
atrium with a mbber-foam tloor designed
to look and feel like an outdoor park com-
plete with flowing "brook" and a bridge
to cross it. Teen-age patients will enjoy
their own private lounge stocked \\ ilh
music and video games. (It is so "cool"
that parents must be accompanied by
theii' teens to access it.) The lobby will
feature a dazzling, two-storied continu-
ous motion sculpture.
' Annually, more than 72,000 children
from all 100 North Carolina counties
come to N.C. Children's Hospital for in-
patient and outpatient treatment. UNC
offers a full range of pediatric specialty
and subspecialty care, including compre-
hensive intensixe care, a Level-I Trauma
Center and a state-of-the-art bum center.
UNC is one of just two hospitals in the
Southeast to perform living-related li\er
liansplants.
' Nationally and internationally renowned
experts in the fields of cystic fibrosis, on-
ciilogy, hemophilia, sickle-cell disease,
infectious disease, genetics, neonatology,
child abuse, endocrinology, bron-
choscopy and congenital heart disease
work at UNC Hospitals. Our facult\
consult with community doctors through-
out the state 24 hours a day.
The Newborn Critical Care Center cares
for more than 750 babies a year from all
over the Southeast. About one-third of
the babies are transported here by pedi-
atric-trained specialists with the UNC Air
and Ground Transport Service.
Facts about the
N.C. Women's Hospital
The N.C. Women's Hospital was
designed to offer patients and their fami-
lies as much comfort and privacy possi-
ble. All patient rooms are private and
feature a conversation area, private bath
w ith tub and shower, and a convertible
sofa to accommodate relatives spending
ihcnighl.
The new facility is conveniently located
and offers a comprehensive, integrated
approach to women's health. Women
from throughout North Carolina will re-
cei\e care in the areas of obstetrics and
gynecology, cardiology, geriatrics, can-
cer, nutrition, alternative medicine, and
beha\ ioral and mental health.
Housing all clinics under one roof
enhances the accessibility of care and
offers a wami. inviting atmosphere to pa-
tients and their loved ones
A Women's Resource Center is planned
for the lobby. It will include an interac-
tive library with literature and journals; a
nurse educator to talk w ith women and
help them find useful health information:
and expanded patient education programs
and seminars currently offered through
the Women's Wellness Network.
5 Hospitals Will Be the
JNC Health Care Family
Thr \.C. Chihlrvns H<.s,nu,l a,ul ,hc \.C. \\nnwu\ l/,n,,„al. Dcluainm cvnus ,nr planncj (or Scpl. S. 20111
• The Irianiile's onls hospnal -havcd.
nurse-midwil'cn, program oporaics liom
N.C. Women's Hospital. MalL'niit\ care
lor all patients — inekidini: lahor. deln -
or\. recover, and posiparliim care — \>, ill
he delivered in one room. There also \m1I
he plenty of space torhahs lo sta\ uith
mom. Rooms located in the maternil\
u int; alsci include rocking chairs.
• The N.C. Women's Hospital uill he
capped u ith a scilarium complete u ilh
touniam and sk> light lo olTer a pleasant. women's and children's medical care
warm and nurturing en\ironmeni lo pa- w ill he li>caied on the second lloor
tients and their lamihes.
•.An outpatient phaiinac), chapel,
• Board-ccrtilieil. nationalh renowned and calcleria are locateil iii the new
physicians oiler care in the areas ol ma- lacihtv,
lernal-lelal meilicine. uiogynecolog), in (Sec irhiu,! slnr\ on pane / U
lertiliis. pen- and post menopause, can-
cer, radiology /mammogra|ih\ and anes-
thesioloiiv
Si\
-■rating rooms deilicatcd t(
Alunini Profile
Alphabet Soup
UNC alum Francis Collins serves up the human genome 'recipe
and sets the stage for a mind-boggling medical revolution
By Lynn Wooten
Last June. Francis S. Collins.
MD. PhD. sUhk! hi ihc Blue
Room of the While House,
looked around and found
himself in the company of ambas-
sadors, senators and other go\emmeiil
heavyweights. Soon, even the president
of the United States would he joining
him. After 10 long years of preparation
and work, this was. at last, the big da\
— the announcement to the world that
Collins, his research staff at the Nation-
al Hiuiian Genome Research Institute,
and scientists working together at labo-
ratories around the world had cracked
the hiuiian body's genetic code, an as-
tounding feat that promises to change
medicine forexer
Yet in a few moments, Collins, w ith
President Clinton at his side, would
enter the East Room, step up to a podi-
um, and in front of a roomful of re-
porters mask an internal conflict of
devastating irony. Just four days earlier,
his sister-in law had died of one of the
most dreaded and common diseases to
strike women. Ha\ ing spent the previ-
ous day at her funeral and comforting
his grie\ ing brother, Collins was stRick
by the unique hand fate had dealt him.
"The juxtaposition here of an exhilarating
moment in science, with such promise for
the future of medicine, and the reality of how
this had come much too late to help this
wonderful woman, had me a bit confused."
Collins said. "It v\asabil Jannng."
It's no wonder.
The decoding of the human genome —
the molecular makeup of a himian being —
is hailed as the prerequisite leap toward un-
locking the secrets of disease, illness, bnlh
defects and other health issues that have long
st\ mied researchers and physicians. In other
words, knowledge that might save millions
of women like his sister-in-law in the future.
As Bill Clinton entered the Blue Room
and approached him. Collins temporarih
shook off these family concerns.
6
Francis Collins. MD '77
"I thought, "This is really going to happen.
This is a pretty big deal.' Pretty soon, we are
w alking into the East Room while the band is
pla\ ing 'Hail to the Chief.' Tliat's lui experience.
"When I was a medical student and house
officer in Chapel Hill, the notion that my path
would somehow lead to that kind of an e\ent
would have been completely unthinkable."
COLLINS' YEARS AT UNC almost
didn't happen.
"I was on the launching pad to go to that
other university called Duke w hen the More-
head Foundation expressed an interest in
interviewing me for one of three Morehead
fellowships." he remembered. "So I came to
Chapel Hill w ith m\ heart in m\ mouth in
early Februar\ of 197.^ to be interviewed
w ith five others. Christopher Fordham
w as the chairman of the Morehead
medical fellowship inter\ iew commit-
tee. I really fell in lo\e w ith the tow n
and the uni\'ersity that weekend."
Within days, he was accepted.
The decision to enter UNC's School
of Medicine was not his first career
change. Always interested in science,
the Virginia native had first gone to
Yale University to obtain a doctorate in
physical chemistry.
"I thought that's what I wanted to do.
but I disco\ ered there were some pretty
exciting things gomg on in biology and
genetics." although not advanced
enough yet for human application. "So
I went to medical school in quite a bit of
confusion abt)ut w here my ow n path
would lead."
Would he focus on science and re-
search or. as he phrased it. on "simply
being a good doctor?"
Collins found his answer. A brief
course in December 1973 by Henry
Neil Kirkman Jr.. MD, looked at the ba-
sics of human genetics. Kirkman pre-
sented a patient w ith sickle cell anemia
and illustrated in a pow erful w ay how a
simple misspelling in the DNA code
could have profound consequences for
the health of that indi\ idual.
"\M I was captisated," Collins said. "This
brought together my interests in science and
a principle-based approach to understanding
problems with a direct application to human
health. 1 knew at the end of those two w eeks
that w as w hat I w anted to do — I w anted to
he a physician who used the tools of genetics
to trv to understand disease better."
GRADUATING FROM the School of
Medicine in 1977. Collins undertook his
residency and a chief residency at UNC.
"I have very warin feelings for him. He
was always a hard-working but joyous
person to be around." said classmate David
C. Henke, MD, assistant professor of medicine
at UNC. "He walked around with a cup of
Collins iiHikes reimirks at June 2000 news conference held in the White House.
ct)tYee all the time because I don"t think he
e\er slept. And he was a stickler for getting
things right. e\en from the teachers. If
an instructor ga\e out what Francis knew was
incorrect information, he would ne\er let it
slide."
Collins. 50. said he had sp)ecial mentors at
L'NC. "The one that stands out most for me
was the late John Parker, a consummate
ph\ sician ... the kind e\er\ one would hope to
belike."
Recalling the first week he was in charge
of patients during his residencs. Collins said
Parker, a Kenan professor of medicine, w ent
behind him to make sure he had not ""missed
an\ thing." Parker's manner, though, was not
threatening; rather, it was inspiring. Collins
said. ""I wanted to ha\e that same kind of
breadth and thoroughness.""
Collins returned to 'Sale for a fellowship in
human genetics, w here he worked on methods
of crossing large stretches of DN.A to idcntif\
disease genes. Joining the facult> of the
L'ni\ersiiy of .Michigan in 1984. he continued
to develop these ideas, w hich he called "posi-
tional cloning.""The concept developed into a
powerful component of modern molecular
genetics, as it alknvs the identification ot
disease genes for almost any condition w ith-
out knowing beforehand what the functional
abnomialitv might be.
Using this strategv. Collins and Canadian
researchers identified the gene for cystic
llbrosis in 1989. followed by the discoveries
of the genes fiir neurofibromatosis and
Huntington's disease.
In 199.^. Collins became director of what
is now known as the National Human
Genome Research Institute, the public
organization that is part of the National
Institutes of Health. The NHGRI was
charged with the task of mapping and
sequencing the human genetic code, as well
as identifying and recommending solutions
to ethical, legal and social issues that could
result from the human genetic code. The task
includes sequencing all .VI billion biochemi-
cal '"letters"" of human DNA. the coded in-
structions — the '"recipe" — for a
functioning human. Using this instruction
book, scientists can begin to ferret out in a
molecular w av the secrets of human health
and disease. With the working draft of the
genome sequence completed and a finished
version — which will be as complete as hu-
mans and computers can nuike it — expected
before 2003. experts predict monumental ad-
vancements into diagnosing and treating
everv thing from cancer to .•\l/heimer"s dis-
ease.
"THE ACCOMPLISHMENT." Collins
said, '"is clearly a milestone of the highest
order.""
Don"t think Collins is patting himself on
the back, though. Eschew ing even the notion
that he might w in the cov eted Nobel Prize for
his work, he seems quite uncomfortable w ith
the praise lauded on him. He quickK credits
"a long list of heriiic figures in science"" for
their contributions. ""This milestone was their
work."
Others recognize Collins' imprint on the
project.
"He is clearlv at the lop of his profession.""
Henke said. '"He is right there in what I'm
sure will be the seminal work in medicine for
this century. I'm very impressed w iih his ca-
reer and work."
But striv ing tor the same goal w as J. Craig
Venter. PhD. president and chiel scienlific
officer of Celera Genomics, a private organi-
zation running an independent genome-
sequencing project. Some observers consid-
ered Celera to be the Collins group's chief
rival, but w hile the media trumpeted a "feud"
between the men and their organizations.
Collins saw things differently. The percep-
tion of a nasty, rancorous race to the genomic
finish line, he said, has been overstated
considerablv. But he conceded that such talk
probably inspired his scienlisis and "siiired
thepol."
"1 think competition is almost always a
good thing." Collins added.
.And contrary to media reports that Clinton
forced Collins and Venter to work together in
jointly announcing the status of their
research. '"I had no pressures coming dow n
from the White House to take a particular
action." Collins said. "The media got that
wrong."
('onliiiKfil (in I'liiie S
7
Alphabet Soup
Ciiiiiiiuicil Jioiii /'((,1,'c 7
With the first draft of the
genome map in place, the world
now can expect a new
competition, one w ith staggering
fmancial stakes. Amied u ith the
human genetic code, phamiaceu-
lical companies alread) are rac-
ing to develop drugs and other
therapies geared to an indi\ id-
Lial's own genetic makeup. Such
personalized treatments should
dramatically improve a patient's
care and response.
'"E\er\ phannaceutical compa-
ny is counting on this." Collins
said. "You w ill see a transfomia-
tion in how medicine is prac-
ticed."
While new medical and scien-
tific advancements will occur
steadily, people shouldn't expect
a cure for cancer or diabetes next
year, he added Although the
genome's letters have been prop-
erly sequenced, scientists don't
yet know what their "Book of
Life" means - they can't read it
yet. And many experts believe
that understanding the genome's language
will be a much more difficult task.
■"The thing that people w ill notice in tenns
of their ovv n medical care ov er the next fiv e to
seven years will be the increasing availability
of DNA tests that will allow people to deter-
mine their indiv idual risk of future illness."
Collins pointed out. "In particular, know ing
you are at high risk and allow ing you to do
something about that risk. For instance,
something like colon cancer- those at high
risk taking advantage of colonoscopy in
order to pick out those tumors w hile they are
small and easilv removed."
.^Xnd therein lies an ethical debate over
genome research; Should patients be told
they likely will be stricken with an illness or
disease later in life, particularly if there is
little medical help available at the time?
"Indiv iduals ought lo have the chance to
make up their minds of w helher thev w ant
Collin
gniihlctai
ith daughters Margaret, left. Elizabeth, right.
tghter Ahby.
that information or not." Collins said.
"Nobody should force that information on
people w ithout them deciding they want to
know that. I think many people w ill not want
to know about risks for which there is no
intervention available. I would say. "No.
thank vou." "
CONTROVERSIES AROUND the
potential contlicts between religious and
scientific v lews of humanity intrigue
Collins, a self-described "serious" Christian.
"I have not found those conflicts at all,"
he said, suggesting that such controversies
lack factual understanding about the
genome and the research process. Finger
pointing between the w odds of science and
religion "points out to me how big an infor-
mation gap reallv exists." he said.
But that debate mav be left to others once
Collins" work is finished in a
couple of years. What's next for
his career?
""That's a very good question,
and I have absolutely no idea."
he admitted. ""I don"t
intend to retire from the federal
government. I feel I have another
career or two in me. but I don't
know what they iu"e yet. I'm tov-
ing with a bunch of options, but
am in some confusion over
which one makes sense. It will
be very hard to llnd something to
do after this that has the same re-
markable intensity and impact."
Meanwhile. Collins and his
wife. Diane Baker, a faculty
member at the University of
Michigan, continue a commut-
ing marriage, w hich he called ""a
bit of a challenge, but we've fig-
ured out how to handle this pret-
ty effectively."
Collins also spends time rid-
ing motorcycles and playing the
guitar, including gigs with his
own band. He enjoys v isiting his
two daughters: Elizabeth, a medical social
worker in Ann Arbor. Mich., and Margaret,
who recently gave Collins his first grand-
child, a girl named Abbv.
Margaret Collins Hill. MD. is a 1996
graduate of the UNC School of Medicine,
where she also undertook her residency in
internal medicine and is now a fellow in
nephrology. Collins is thnlled that .Margaret
is in Chapel Hill and at his alma mater.
""I can't think of a better place w here
I'd like a child of mine to spend her time."
he said. □
Health Affairs Bookstore
Has A New Home
By Michele Blevins
It you haven't visited the L'NC
Health AtTairs B(H)kstore re-
cent!}.. _\ou ina\ mn recogni/e
the place. The hooivstore has
relocated and expanded just a bit
— it now occupies tour floors of a
brand-new fi\e-siory building.
h"s quite a change from its pre-
\ ious location — on the first floor
of the Brinkhous-Bullitt Building
— \v here the sales floor w as only
600 square feet. In its new home,
the bookstore has a sales area of
7.000 square teet. more than 10
times its original size.
.All that additional space has en-
abled the biHikstore to enhance the
variety of features and services it
offers the UNC health affairs community.
The depth of inventory on books, for
example, has signiflcantly increased. Selec-
tions now include popular book titles, com-
puter manuals, cookbooks and children's
books, all in addition to the ever-present
classroom texts, studv guides and medical
reference titles for health affairs students.
But customers will And much more than
just hooks when thev visit the store
Computer software and supplies and a vari-
etv of medical equipment and accessories
are just some ot the new items the bookstore
carries.
A full line of medical apparel is available
for students and health professionals alike,
including lab coats, nursing unitomis. scrubs
and clogs.
In addition, clothing and gitt items aie
available that represent all ot the L'NC health
affairs schools, including the .Allied Health
Sciences programs. Fhe store's selection ot
UNC collegiate clothing and gifts has
increased as well.
And for anyone who wants to uiiw iiul
with a cup of coffee or u snack, there's Cate
Caducous — the store's coffee shop — locat-
ed on the third floor ot the buildin::. which is
The ncu Hcalili Affairs Bookstore.
acluallv the store's main entrance level. In
addition to a seating area w iih laptop connec-
tions inside the cafe, there also are outdoor
seating areas on the second and third floors
of the building.
The second floor includes a conlerence
room that can hold up to .^0 people and is
available tor use bv health alTairs tacul-
ty. staff and siudents. .Also located on
the second floor is a L'NC Printing
Copy Center, w hich relocated trom its
former home in the MacNider Build-
ing.
The store is well-equipped to handle
the rush of students buying textbooks in
the first weeks of classes each semester.
There are six cash registers located
throughout the store to reduce students'
waiting time during peak book-buving
season.
Like other L'NC Student Stores, the
Health Aflairs Bookstore is a non-profit
operation that doesn't receive state
lunding. The store's profits go toward
non-athletic scholarships for L'NC stu-
dents.
The Health Affairs Bookstore is
located on Medical Drive, behind
Carrington Hall (School of Nursing)
and adjacent to Fordham Hall. Hours of
operation ;u"e Mondays through Fridays
from 7;.^() a.m. - 6 p.m. and Saturdays
from 1 0 a.m. - 2 p.m. D
A peck in\ulc llic first floor
Dean's Choice
By Leslie H. Lang
How does life work? How does a
lour-letter alphabet spell out
instructions for all species on
earth'.' How does the union of a
single egg and sperm become a baby of five
trillion cells? What can the study of molecular
mechanisms tell us about disease'
In a sprawling and bustling Fordhain Hall
laboratory. WUliam F. Marzluff. PhD.
professor of biochemistry and biophysics,
the School of Medicine's executive associate
dean for research, and director of the pro-
gram in molecular biology and biotechnology
seeks answers in this arena of big questions
by focusing small, very small.
He and his graduate students and postdoc-
toral researchers study the regulation of gene
activity; namely, the system of biochemical
switches that turn genes on and off during the
mammalian cell cycle and during early
development in frogs and sea urchins.
Sometimes the work takes Marzluff to the
edge of life's very beginnings, each
e.\]:>eriment moving a .step closer to unraveling
the biochemical mystery of embryogenesis.
the process by which an egg transforms into
an embryo.
At the heart of this research is a unique
cellular protein that Marzluff "s UNC labora-
tory discovered and cloned in 1996. This
"stem-loop binding protein." v\ hich latches
onto the looped tail of histone messenger
RNA. signals the synthesis of histone
proteins crucial to cell functioning during
embryogenesis and throughout the organism's
life. In fact, about half of the nucleoprotein
complex known as DNA are histone proteins.
But SLBP does more than simply hitch a
ride on a loop of nucleotides. It also doggedly
peifonns a string of important duties after it
takes the mRNA into a specific region of the
nucleus. It interacts with other proteins to
make sure the mRNA is properly processed
into its tlnal form. And then after helping get
it out to the cytoplasm, the cell's factory
tloor. SLBP remains bound to the mRNA.
making sure that its instnictions are properly
translated.
From w hat is known about it so far. that's
pretty impressive for a compact protein.
10
Indeed, according to the latest findings, it
may be the fundamental regulator of all the
histone genes which are essential for
chromosome replication.
In some characteristic ways. Marzluff 's
protein serves as metaphor for the man.
Here's what David Lee, PhD. chair of
biochemistry and biophysics, says about his
colleague.
"I view Bill Marzluff as one of our best
assets, and I know that view is shared by a
number of major scientific leaders who are
here largely because of Bill's recruitment
efforts. No one brings more positive and
creative energy, as well as sheer stubbornness,
to promoting basic science at Carolina. Bill
has an almost unique ability to work w ith
biomedical scientists of e\ery persuasion,
from biologists to biophysicists. and is
implicitly trusted by the entire community. 1
am particularly proud to ha\e served on the
search committee that recruited Bill to
UNC."
Science faculty both in and out of the
School of Medicine sing similar praise for
Marzluff. The university is widely regarded
for its interdisciplinan' biomedical research,
which he tirelessly nurtures and promotes.
"One great attraction to this university is
the really top quality undergraduate school in
close proximity to some of the best science in
the world. There are not too many places that
have this combination physically close to
each other w here they actually do interact,"
Marzluff obsenes.
And it is to this active research nucleus
that Marzluff strives to shepherd new faculty.
"Part of the job that appeals to me is the
opportunity to recrtiit young faculty and help
them develop. Chapel Hill is a wonderful
place to recmit to because of the living condi-
tions and the collegiality. That's one reason
that we're recruiting extremely competitively."
One might be drawn to conjure an image
of this UNC scientist-administrator complete
with rep tie. Tar Heel megaphone and lab
coat of Carolina blue. Instead, how ever, think
khakis, tennis shirt and sneakers. That is.
think grad student, v intage early 1970s. Still,
for those special events and conferences, a
navy blazer, proper shirt and tie hang behind
office door.
Actually, the student image fits appropri-
ately, sartorially and professionally. His is a
fast-paced research field vv ith rapidly changing
technology. And, as Da\ id Lee points out.
the growing emphasis on interdisciplinary
approaches to human disease dictate that
biomedical scientists "be fast on their feet —
proficient at self-education and able to
integrate infonnation across a wide spectrum
of fields."
Bill Marzluff readily admits that he has
gone back to school, as it were, .several times
during his career.
At Hanard in the mid-1960s (BS, Chem-
istry. '67). his interest in biochemistry devel-
oped at a time when an undergraduate major
in that field did not exist. ( Marzluff 's father
was a research chemist for American
Cyanamid.) Biology had not become very
molecular. Cell biology was microscopy, in-
cluding much electron microscopy. The ge-
netic code, the secret words of DNA.
remained largely unplumbed.
Marzluff earned a PhD in biochemisti"y at
Duke, followed by postdoctoral research at
Johns Hopkins where he worked on gene
regulation in mammalian cells.
"In temis of making some particular RNA
molecules, we were trying to basically repro-
duce in a test tube some of the reactions that
went on in the cells. You see. you couldn't
clone a gene, a piece of DNA. or grow a piece
of DNA before 1975 or 1976. With the
advent of cloning, you had to stop everything
and re-train yourself
"All the experiments we did before were
on whole cells. Now we could take an indi-
vidual isolated gene and just study that. So
basically you had to stop and re-train. This
meant learning all the new technologies,
buying the stuff and figuring out how to
make it work. So in our area the real excite-
ment didn't come until shortly after we
finished our postdocs.
"Now with completion of the Human
Genome Project, we have to change the way
we approach scientific problems again."
.Marzluff joined the chemistry faculty at
Florida State University in 1974. During 17
years in Tallahassee, he nurtured and sus-
tained a strong undergraduate biochemistry
program. He came to UNC in 1991, and
MarzhitJ ui luuue in the research lab.
e\er\ year at least one student from Florida
State joins UNC's graduate biochemistry
program.
"One of the reasons I went into this busi-
ness was the opportunity to teach.'" Mar/lutY
says. "At Florida State, the a\erage annual
teaching load in the chemistry department
wa.s9()to I (K) lectures. Here I teach one-third
of a first-\ear graduate course and a molecu-
lar biolog) section to medical students. So I
still do a fair amount of teaching. '
Add to that the mentoring of graduate
students and postdoctoral research staff;
meeting grant proposal deadlines for his
lab's research funds: preparing and submit-
ting articles for journal publication: confer-
ence planning: fund-raising on and off
campus on behalf of basic sciences, including
buildmg construction, grants procurement
and facult\ recruitment: organizing and
attending planning conferences: and meeting
myriad other administrati\e responsibilities.
"He's the most effective and unusual
research dean l'\e e\er known." says Jeflre\
I.. Houpl. M. dean of the School of
.Medicine.
"B> mutual agreement, he has no office in
our administrative area, he can work on it as
much or little as he wants — I keep no track
of his time. But he gets agreement on diffi-
cult issues like space, cost sharing, and puts
people together more effectively than an\ one
I'nc seen. His success is that he's not \ iewed
as an administrator. I always wanted a
research dean in this mold and finall\ got it
uithBill."
In his ow n deanship, NUuyluff seems allergic
to limelight. He prefers that it shine on his
UNC basic science colleagues and their
accomplishments in recent years.
"Some great things ha\e been achie\cd
here, he says. " Creation of the cystic fibri>sis
model mouse by Richard Boucher. Be\erly
Koller. and Oliver Smithies. This accom-
plishment helped increase our understanding
ol the disease and gain neu insights into its
treatment.
".Michael Knowles. Richard Boucher and
others have followed this by studying neu
drugs, the P2Y2 receptor agonists, to treat
lung disease in patients w ith c\ stic fibrosis.
"We had the discoxerv by A/i/ Sancar's
lab that cr\ ptochrome. the no\el pigment
found \\ ithin the e\ e. skin and part of the
brain, controls circadian rhythm, the body's
internal clock. This discovery could lead to
more effecti\ e therapies for depression and
greater safety during shift u ork at night.
".■\nother accomplishment was the
cloning of the molecule I-kappa-B and its
role in regulating cancer cell growth and
death." Marzluff continues. "This research
by W Baldw in is w idel> recognized for pro-
\ iding an understanding of how cancer de-
\ clops and ma\ lead to new methods of
iieatment and prevention.
"■■Xnd just last year Jack Griffith discov-
ered the structure of telomeres, the ends of
chromosomes. This discovery that chromo-
somes end in loops should prov ide a whole
new way of thinking about basic molecular
mechanisms related to cancer and to the
control of aging in cells.
"I've watched Jude Samulski and his
colleagues dev elop the best v ectt)r system for
gene therapv — adeno-associated v inis.
"Then there's last December's discoverv
bv Clvde Hutchison and his colleague at
TIGR (The Institute for Genomics Research)
of the smallest number of genes needed for
an organism's surv ival. This research marks
a significant step toward creating minimal,
tailor-made life forms that can be further
altered for such purposes as making biologi-
cally active agents for treating illness."
The research dean also points to the
appointment last year of biochemisirv and
biophysics professor Terrv Van Dv ke. PhD.
to direct the Mutant Mouse Regional
Resource at UNC. With a S3..'i million grant
over five vears. this is one of only two NIH-
sponsored sites nationally that will facilitate
more widespread use of mouse models in
basic and translational research throughout
the U.S. Such models have revolutionized
the abilitv to probe mammalian biology and
disease and have become a valuable
resource.
Marzluff is proiul that ihc school's
research reputation and collegial interdisci-
plinai") atmosphere make it very competitive
in tacultv recruitment. Some highlv sought-
after indiv iduals were recentlv tapped to
direct new research centers. Recently
appointed are William Snider. MD. head of
the Neuroscience Research Center and Terrv
Magnuson. PhD. Sarah Graham Kenan Pro-
fessor and Chair of the new deparimeni of
genetics. Magnuson also will direct UNC's
Genomics Center, cunently under fomiation.
"This is an exciting time to be involved in
biomeilical research."" savs Marzluff. "And
il"s pailicularlv exciting lo be doing it in the
cnm|\inv (il some ol ilic worUI's besi."' D
II
News
Briefs
UNC Specialty Women's
Center uses high-tech
uhrasound equipment
Doctors and sonogruphers at UNC
Specialty Women's Center in Raleigh now
can perform more detailed examinations of
Linbom babies by using the latest in high-tech
ultrasound equipment.
The new equipment, know n as the HDI-
3()()(). is a high-definition imaging ultra-
sound. The technique offers doctors and
expectant parents such a precise image of the
fetus that it can detect abnormalities like
spina bifida, a defect of the central ner\ous
system that occurs when the neural tube,
which forms the spinal cord and brain, does
not de\elop properly.
Denise Johnson, an ultrasonographer at
the center, has used the HD1-5(MK) ultrasound
since Ma_\ and considers it an indispensable
tool for detecting certain birth defects.
"It's brand new with all the bells and
whistles."" said Johnson. "It helps us study
high-risk obstetrical cases.""
The HD1-5(XH) ultrasound used at the center
offers a closer look at congenital heart prob-
lems, kidney defects and gastrointestinal
abnonnalities.
Obstetricians and gynecologists through-
out the Triangle refer their patients to the
center for prenatal diagnoses, and some
patients ha\c tra\eled from as far away as
Wilmington for the ultrasound.
"We hope to attract more patients from
areas that do not cunently offer this type of
ultrasound, but who could benefit from our
expertise in maternal and fetal medicine.'"
Johnson said.
Wellpath Select, Inc. and UNC
Health Care Sign Provider
Network Agreements
WellPath Select. Inc.. an HMO formedy
owned by Duke Health Systems, and UNC
Health Care ha\ e signed agreements that will
allow WellPath to provide its members
access to the health care provided by UNC
Hospitals and UNC Physicians & Associ-
ates, The contracts include continuing: Well-
12
UNC Health Care unveils new lifesaving helicopter
Loiik. up in the sk_\ 1 It's a bird. it"s a
plane ... no ... it"s the new Tar Heel One.
UNC Health Care"s new. state-of-the-art.
Iitesa\ ing helicopter. Part of the UNC Air
and Ground Transportation fleet, the
chitpper w ill offer patients in medical cri-
sis a faster and safer trip to the hospital.
"The biggest difference is the technol-
ogy."' said pilot Shep Kaylor. The aircraft,
an ECI.^5-T1 manufactured by Euro-
copter, replaces a helicopter made in
the I98()s but which featured I97()s
equipment.
The new Tar Heel One can transport a
pilot, three medical personnel and one
patient and can tly well over 400 nautical
miles. Kaylor said — far surpassing the
250-mile range of the previous chopper.
More fuel efficient, lighter and better
constructed, the new Tar Heel One is also
"more en\ ironmentalK friendly." Kaylor
added. "It bums fuel more cleanly."
The main benefit for patients is the
helicopter's speed -e\ en shaving 10 min-
utes off a night can pro\e crucial for a pa-
tient in critical condition, said nurse
Wend\ Rash, a member of the llight team.
"We will still di> the same type of care
and procedures, but it will help us out be-
cause it is faster." she said. "It also has im-
pro\ed lighting inside for better night
\ision."
Striking in appearance, the helicopter
sports bold Carolina blue and white
stripes, a large painted Tar Heel on its
belh and the new UNC Health Care logo.
Path's long-standing and successful relation-
ship w ith Rex Hospital and its priman ph\ si-
cians. Rex Healthcare in Raleigh is part of
the UNC Health Care System.
With the contracts effecti\e September I .
2( K K ). Wei I Path enhances its already substimtial
pro\ ider network b_\ more than 64 1 specialists
and 105 primary care ph\sicians who are
part of UNC's facultv and community prac-
tices. The contracts include the full scope of
ser\ ices pro\ ided b\ UNC Health Care,
including all its hospitals, physicians and
other health care services, such as home
health and hospice. Both LWC and WellPath
are committed to continuing to build upon
their strong relationship for the greater benefit
of WellPath members and communities
served by WellPath and UNC.
"We belie\e our track record as a leading
health care system enables us to bring great
\alue to WellPath members." said Eric Mun-
son. President and Chief Executi\ e Officer of
UNC Hospitals. "Our experience in the mar-
ketplace, our excellent health care ser\ices
and our positive association w ith many of the
area's employers have enhanced the health
and well-being of the people in this region.
And we belie\e w ith this new relationship
WellPath members will have more choice
through our extensive network of physicians
and hospitals."
UNC wins contract to create
the first Cystic Fibrosis
National Bioinfomiatics Center
The L'ni\er^it\ of North Carolina at
Chapel Hill School of Medicine has been
awarded a contract b\ the C\ stic Fibrosis
Foundation Therapeutics Inc.. an affiliate of
the C\ Stic Fibrosis Foundation, to create and
maintain the nation's first comprehensi\e
bioinforniatics center for c>stic fibrosis
researchers.
The new contract establishes the C>stic
Fibrosis National Bioinforniatics Center in
cooperation \\ ith Infomia.x Inc. The contract
is worth S45().()(KJ over t\\ o years.
As the amount of infonnation about c\ stic
fibrosis continues to grow, scientists are
challenged to carr\ out research that turns
this information into neu therapeutics as
rapidl\ and efficienth as possible. While
there are man) labiiraliiries around the coun-
try stud_\ ing csstic fibrosis, scientists still
lack a commtin "language" \\ ith w hicli lo
exchange know ledge and infonnation.
■"CF researchers at most universities
usually rely on the tools at their university,
meaning that scientists lu'e most often work-
ing independently of each other." said Da\id
Fenstermacher. director of scientific comput-
ing. "One reason for this is that
researchers use different fonnats for storing
data, making it difficult to go to another
cystic fibrosis data site and learn from
infonnation stored there. "
The Cystic Fibrosis National Bioinloi-
matics Center will allow the foundation to
use UNC as a central repository for data
derived from gene expression studies. When
one group uncovers important data, another
participating group can use that information
for its subsequent expenments.
For more than two decades. INC has
been nationallv and internationallv recog-
nized for its premier CF Foundation research
center and accredited care center
The Cystic Fibrosis Foundation will
provide researchers access to Gcnomax. a
database and data-mining tool produced by
Infomiax Inc. to be housed at UN'C where it
can be accessed via the Internet. Technical
and application assistance will he available
i^ound the clock.
"This initiativ e betw een academia. industn.
and a non-profit, voluntarv health organiza-
tion is another innovative tool that will assure
the progress of science and of cv stic fibrosis
research in particular." said Robert J. Beall.
president and chief executiv e officer of the
CF Foundation. "CF scientists hav e a great
track record for collaborating to move CF
research forward. This continues to fonn the
cornerstone of our success."
The Genomax database will be prov ided
to a limited number of participating cv stic
fibrosis researchers for free, and these inves-
tigators will have private v irtual wnrk areas
w here thev can analv /e their data. Eiv entuallv .
however, each participating scientist will be
required to submit his or her data lo the
central repository, iherehv making it accessible
to other researchers.
"Bv providing access to this powerful
gene analv sis tool and centrali/ed database,
the CF Foundation hopes that scientists will
use the tools of functional genomics and
protein structures to identify nov el targets for
future drug development." Beall said.
.According to Fenstermacher. the Cv stic
Fibrosis National Bioinforniatics Center
should become available to CF researchers
this fall.
Eck, Viall appointed directors
of women's and children's
programs
UNC Health Care recently appointed two
new program directors for its N.C. Women's
and Children's hospitals, currciitlv iiiuici
construction.
.Sharon Fck has been named director of
the N.C. Women's Hospital. Carolyn Viall
has been named clinical mirsing ilireclor lor
Chiklien's Services.
Before coming to L'.NC last summei. I:ck
served as project manager of Senior Nursing
Administration and Patient Care Serv ices at
Yale-New Haven Hospital in New Haven.
Conn. She said the challenge of tailoring
programs offered in a brand-new. state-of-
the-art facilitv attracted her to Chapel Hill.
Lck
"We're going to
respond to what
w omen w ant." she
said. "We're going
to give them chitic-
es. shared
Llecision-m.iking.
convenience and a
caring, human con-
nection."
Eck received her
hacheUtr's of sci-
ence degree in
nursing in U)8.^ and
her master's degree in nursing in l9Sft from
the Universitv ot Iowa. She
earned her doctorate in nursing from '^'ale
University.
•An assistant professor in the UNC School
of Nursing. Eck sits on the National
Research Committee of the .American
Association of .Ambulator) Care Nurses. She
is a member of the .American Nurse's .Asso-
ciation.
Viall comes to
LINC from the
Medical Univer-
sity of South
Carolina, where
she served as
nurse manager of
the Pediatric
Medical-Surgi-
cal. Pediatric
Oncolog).
Pediatric l:n-
docrinc and
Renal, and Pedi-
atric Cardiac units.
"We aim to deliver world-class caie. ami
we want lo be the top choice among parents
aiul lelerring ph) sicians for pediatric care."
she said.
Viall earned her bachelor's degree in nurs-
ing from Cleveland State Univeisit) in I'JSI
and her master's degree in nursing from Case
Westeiii Reserve Univeisit) in IMSd.
.A member of the .American Association of
Critical Care Nurses. Viall serves on the
■Amencan Sociel) for Parenteral and linteral
Nutritions Public Policv Committee. In
l'^>S. she was awauleil the South Carolina
League lor Nursing Award ol l\ccllcncc.
1.^
Violl
Family Day 2000
Under perfect Carolina
blue skies, a large crowd
enjoN'ed Family Day ac-
tivities held Sept. 16 at
UNC's Carroll Hall.
School of Medicine Dean Jeffrey
I.. HoLipt welcomed almost 500 stu-
dents, family and friends, one of the
biggest groups e\er to attend the
e\ent. Other faculty members par-
ticipating in the program included
GeiT) S. Oxford. PHD. professor of
cell and molecular physiology;
Georgette Dent. MD. associate
dean for student affairs. Stephen J.
Ki/er. MD. professor and associate
chair for medical education;
and Beat Steiner. MD. MPH. clini-
cal assistant professor of
family medicine.
James B. Brame. Jr.. of Durham,
who's daughter Amy graduated m
199S and now daughter Anna is a
first year student spoke to parents.
Brame told parents that the life of a
medical student revolves around
four "S" words: study, stress, sacri-
fice and sleeplessness.
"These words are easy to under-
stand and we all know that our fu-
ture doctors experience all four in
prescription doses. We can help
them w ith another "S" word. That is
support. ... I ask each of you as par-
ents to seek out and find opportuni-
ties to volunteer your time and
talents to the medical school."
Follow ing lunch cm the lawn,
first year students and families ad-
journed to Memorial Hall for the
traditional White Coat Ceremony.
This year's speaker was Stewart
Rogers. MD. professor of medicine
w ho leads the Internal Medicine
Training program at Greensboro's
Moses Cone Hospital for AHEC.
The White Coat ceremony origi-
nated at Columbia Uni\ersit\ 's
College of Physicians and Surgeons
seven years ago.
The ceremony is designed to fos-
ter the ideals of humanistic, com-
passionate patient care, ethical
conduct, and personal responsibili-
t\ in the learning of medicine. UNC
held its first White Coat Ceremony
in 1996. About 160 first-year med-
ical students received their coats
during the ceremony before a
standing-room only crowd. The
ceremony concluded with the stu-
dents reciting The Oath (see next
page) dedicating themselves to
the responsibilities of a physician
intrainins:.
Gcoviicnc Dent. Ml), ilsmk uilc Jciin Jcr sludcnl iilhiirs. hikes
a lii^hr-hcarteil moment ihiriiig her presentation as part of the
Family Day program.
Sliulents i^et chance to catch up with taiiiilx at lunch.
.\ stiuleiit panel shares perspective of medical school life with parents who
attended Familx Da\ events.
Snulfiu^. fciiuilx and tru-nds hud 'lunch on die hiwn " mnsidc Currod Hidi
The Oath
I acknowledge and accept the privileges and responsibilities
i;iven to me today as a physician in training and dedicate myself to
provide care to those in need.
I will approach all aspects of my education with honesty and in-
tegrit\: embracing opportunities to learn from patients, teachers
and colleagues. The diversity of their experiences, cultures and
beliefs will enrich my education and my alvlity to car for patients.
When I feel unprepared for new responsibilities. I will
acknowledge my limitations and seek guidance.
I will respect the humanity, rights and decisions of all patients
and will attend to them with conipassiim and without bias. I will
maintain patient confidentiality and be tactful in my words and
lU tions. I will not forget that there is an art to medicine as well as a
science and that warmth, wiiipalhx and understanding are inte-
gral to patient care.
I recognire the privileges afforded me as a physician in training
and promise not to abuse them. I will .urive to earn the tni\i m\
patients place in me and the respect that society places upon ni\
profession. As a student. I will .'ieek to acc/iiire the kiunvledge and
skills needed for individual patient care, the capacitx to prevent
illness and to understand the wars that I can contribute to the stan-
dard of health in my community.
.As I accept these new responsibditics. I will not loiget the im-
portance of my own health and well-being. I will continue to value
mx relations with those who have supponed mc in the pa\l and
those who will share in nn jiiuirc.
Students recite The Oath ihiriif^ the White Coat Ceremon\ held at Memorial Hall.
Fivhiin^cr
Faculty
Notes
Robert A. Bashford, MD. clinical associ-
ate professor of psychiatr\. has been elect-
ed to the membership of the American
College of Psychiatrists.
Janet K. Freburger, PhD. PT. has been
selected as the 2000
recipient of the
Dorothy Briggs
Memorial Scientific
Inquiry Auard from
the American Physi-
cal Therap\' Associa-
tion. Freburger has
also been selected to
recei\e a National
Research Service
Award from the Agency for Health Care
Policy and Research of the U.S. Public
Health Ser\ ice. beginning in Jul\ 20()().
Noelle A. Granger, PhD. professor of cell
biologs and anatomy, has recei\'ed a grant
from the Educational Technology Group
for the purpose of de\elopment of gross
anatomy dissection guides using comput-
er-based resources with the aid of Jesse
Cannon. Granger also received a grant
from ETG to develop 3D embryology ani-
mations.
Gail E. Henderson, PhD. and Nancy
M.P. King, JD. both professors of social
medicine, are leading
a group of colleagues
who ha\e been aw ard-
ed a three-year.
$975,000 National
Human Genome
Research Institute
grant to in\estigate
ethical issues sur-
rounding gene trans-
fer studies. Hender-
son. King and colleagues will interview
investigators, research subjects, study
coordinators and members of institutional
review boards in up to 50 of the most
recent gene transfer studies across the
L'nited States. The group will also analyze
the specific language of consent forms in
such studies in an effort to understand how
people develop ideas and beliefs about
possible benefits from gene
Henderson
KIni;
transfer/research
studies. .Also
involved in the pro-
t arc Larry R.
Churchill, PhD. pro
lessor of social medi-
cine; Daniel K. Nel-
son, MS. associate
professor of social
medicine and pedi-
atrics; Arlene Davis, JD. research assis-
tant professor of social medicine; and
Michael O. Calloway, a fellow at the
UNC-CH Cecil G. Sheps Center for
Health Services Research.
Celia R. Hooper, PhD. clinical professor
of speech and hearing sciences, has been
honored bv L!NC-Greensboro's School of
Health and Human Performance with its
Distinguished .-Xlumni Award.
Jean M. Lauder, PhD. professor of cell
biology and anatomv. has recently received
two awards. NIDCR has granted Lauder a
five-year award titled "Serotonergic Regu-
lation of Insulin-Like Growth Factors."
NIEHS has funded ""Organochlorine Pesti-
cides and Serotonergic Development." a
two-vear aw ard.
John J. Lemasters. MD. PhD. professor
of cell biology and anatomy, has been
granted a two-year Collaborative Funding
.Assistance Program award from the N.C.
Biotechnology Center for his research pro-
ject titled "Development of Carolina Rinse
Solution."
Jeffrey .\. Lieberman, MD. professor and
vice chair for research and scientific affairs
of psvchiatry. and Christine Marx, MD
received the 2000 Kempf Award from the
American Psychiatric
Association. The award
recognizes research
excellence in schizo-
phrenia, and is given to
an outstanding mentor
and his/her mentee.
Lieberman recently
served as part of the
planning board for the
Lichcmuin Surgeon GeneraLs
Report on .Mental Health.
Gary B. Mesibov, PhD. professor of psy-
chiatrv and director of TEACCH. has
received an honorary doctorate from the
academic board of the Univ ersity of Mons-
Hainaut in Mons. Belgium. The Belgian
university recognized Mesibov for univer-
sity training and public school implemen-
tation of TEACCH methods in Belgium.
TEACCH was the first program in the
United States to offer comprehensive and
community-based professional assistance
for families to help them understand and
treat autism and avoid unnecessary institu-
tionalization.
Anthony A. Meyer. MD, PhD. professor
and div ision chief of
general surgery, has
been named the
Roscoe Bennett Gray
Cowper Distin-
guished Professor of
Surgery. He succeeds
George Johnson. MD
who was the first
Cowper Professor,
and who now is the
Roscoe Bennett Gray Cowper Professor-
Emeritus. Mever has also been appointed
reviewer for the Journal of Leukocyte
Blolo\;y. chairman of the Honors
Committee. Nominating Committee and
Committee on Publications for the Ameri-
can Association for the Surgery of
Trauma, and was appointed to the Strate-
gic Planning Task Force for Ambulatory
Care Pharmacy last year.
Michael R. Mill, MD. professor of
surgerv. has been named chief of the divi-
sion of cardiothoracic surgery. He has been
the acting chief
since Benson R.
Wilcox. MD.
retired in 1998. Mil
performed both the 'Tt3^
first heart-lung
transplant and first
pediatric heart-lung
transplant in North
Carolina.
Mill
Merer
J^^
Paul L. Molina. MD. associate professor
ol radiologv uas
selected by the diag-
nostic radioiogN res-
idents as Teacher iil
the '^ear. The award
honors a UNC facul-
ty member who
makes a significant
contribution to radi-
ologN resident edu-
Moliiui cation during the
academic year. Molina joined the facult\
in 1993 and has ser\ed as the residency
program director for the department of
radiiilog\ since 1996. He"s the director of
computed body tomograph\' and chairman
of the radiology resident selection com-
mittee.
Shoji Osawa, PhD. research associate
professor of cell biology and anatomy, has
recei\ed a three-\ear award from NTH
titled "Desensiti/ation of Cone Visual
Signaling Pathwa\s."
Michael D. Peck, .MD, ScD. professor of
surger\ and director ol the L'NC Ja\cee
Burn Center, has been appointed to the
editorial board of the Jounuil of Hum
Care and RehabUitation.
The Journal is the official publication
of the American Bum Association and is
the only U.S. journal de\oted e\clusi\el\
to the treatment and rehabilitation of
patients with burns. Its original, peer-
re\iev\ed articles present the latest infor-
mation on surgical procedures, acute care,
rehabilitation, reconstruction and burn
pre\ention.
Robert L. Peiffer, Jr.. PhD. DVM. pro
fessor of ophthalmology and patholog\.
was recentK in\ited to be a \isiting pro-
fessor at the Western Colleges of .Medi-
cine and Veterinar\ Medicine. L'ni\ersit\
of Saskatchewan. Saskstoon. Canada. In
addition to participating m patient rounds
and collaborati\e research with Dr. Bruce
Grahn. Peiffer ga\e three lectures while
there. "Ocular .Melanomas in Three
Species." "The Histopathology of Glauco-
ma." and "Pigmented Ocular Lesions."
M. Patricia Ri\cra. MD. assistant pro-
fessor ol pulmonar\ and critical care med-
icine, has been appointed go\ernor of
North Carolina for the .American College
of Chest Physicians for 2()()()-2()()2.
Wesley M. Wallace. MD. clinical assis-
tant professor of emergency medicine, has
been appointed bs House Speaker James
Black to the North Carolina Legislature's
Smart Grovsih Commissiim.
Robert D. Lansdell. MD. professor
emeritus of patholog\ and laboratory medi-
cine at the UNC School of Medicine for
more than 30 years, passed awa\ April I 1.
2()(M). Despite his death at age 7ft. his life-
time of contnbutions to the fields of hema-
tolog\ and pathologs will continue to li\e
on.
"Dr. Langdell was one of the three
world-famous coagulationists that UNC
has produced." said Harold R. Roberts.
MD. distinguished professor of medicine
and pathologN and laboratory medicine.
"Dr. Langdell. along with Dr. Kenneth
Brinkhous and Dr. Robert Wagner, is
known the world o\er for the Partial
Thromboplastin Time test that the three first
developed and described in 19.S.\"
The Partial TTiromboplastin Time test, or
PTT as many physicians call it. is a simple
bl(K)d test used for the diagnosis ol bleeding
disorders and for monitoring treatment ot
heart attacks and strokes w ith the anticoag-
ulant heparin. The test is currentls used mil-
lions of times a day by hospitals worldw ide.
according to Roberts, and has tormed the
basis of all other one-stage clotting
assass used.
IN REMEMBRANCE
R,,hcn I) luiir^chll. Ml)
"Dr. Langdell's contributions lo his licld
included not only the de\elopmeni of PIT
and his expertise in the diagnosis of bleed-
ing disorders." said Roberts, "but also his
enumeration of the requirements on blood
banks to treat those disorders w ith blood
component therapy."
.•\ graduate of the George Washington
L'niversit) School of Medicine in I94S.
Lansidell first came to L'NC as a fellow in
patholog) in 1944. Hcquickl\ became a
ke\ member of Brinkhous' research group,
and began teaching in the department of
pathology in 1951. His research interests
included the nature of coagulation in lower
animals, and the stability of coagulation
factors in blood-banked blood and plasma.
Throughout the course of his distin-
guished career. Langdell was invohed in
numerous professional affiliations, includ-
ing the .American Medical .Association, the
American Society of Clinical Pathologists
and the International Sociels of Lhrombo-
sisand Haemostasis
Langdell retired from the School of
Medicine in June of 19S9. In 1990. the
Langdell Transfusion Medicine Service,
the blood bank for L'NC Hospitals, was
dedicated and named in honor ol Langdell,
Langdell's achiev e men is w eie once
again lecogni/ed in l'>4ft when ihc Ameri-
can .Association of Blood Banks awarded
him their highest honor, the Karl I.andstein-
er .Award. The award is given annuallv in
recognition of those who have made out-
staniling contributions iii the science ol
blooil-banking at both the clinical and basic
research levels.
Faculty Profile
Runge Stays Focused on
By Katie Macdonald
During the hottest days of summer,
w hen many North Carolinians ure
complaining of the heat and hu-
midity, Marschaii Runge. MD.
PhD. and new chair of the UNC
Department of Medicine, is thoroughly
enjoying the blue skies and casual, university
town lifestyle unique to Chapel Hill. "It's
like a breath of fresh air." said the native
Texan, who has found relief from the Texas
heat along with some new challenges that
come with chairing one of the largest depart-
ments w ithin the School of Medicine.
"ril do my absolute best to help the de-
partment grow and prosper and to foster
growth in our faculty, fellows, residents and
staff." he said, ""rm excited to be here and
will do e\erything I came to help continue
the outstanding tradition that this department
has had o\ er the past se\ eral decades. "
In July. Runge moved his w ife. Susan, and
their five children. Thomas. 17: Elizabeth.
1."^; William, 13; John, 10: and Mason. 8.
from from Gaheston, Texas, where they had
lived since 1994. in Texas, Runge worked in
the cardiology di\ ision at the John Seal\
Hospital — University of Texas Medical
Branch at Galveston. Along with his role as
professor of internal medicine and John
Sealy Distinguished Centennial Chair.
Runge ser\ed as the director for the Sealy
Center for Molecular Biology, all while
fulfilling his duties as an attending physician.
His medical career is replete with distin-
guished academic and hospital appointments.
He graduated from the Johns Hopkins
School of Medicine and was an intern and
resident in Internal Medicine there. He then
completed his cardiology fellow ship at
Harvard's Massachusetts General Hospital
and was a faculty member there prior to
mo\ing to Emory Uni\ersity as an associate
professor of Medicine in 1989. 0\erthe
\ ears, he has recei\ ed numerous aw ards and
honors that are reflective of his outstanding
career as a researcher, teacher and physician.
His research awards include the Henry
18
Marschaii Rnui;c. MD. chair of the Department of Medicine
Christian Research .^ward from the Ameri-
can Federation of Clinical Research and the
American Heart Association Council on
Thrombosis" Young Investigator Prize in
Thrombosis.
Runge also has received praise from some
of the top medical schools in the country. In
1993, Emory University honored him with
the Golden .Apple .•\ward for excellence in
teaching in internal medicine and. in 1994.
the University of Texas Medical Branch
designated him the Best Teacher in Internal
Medicine. The Best Doctors in .America also
counted Runge among the select doctors for
its fourth edition issued in 1998. For a doctor
whose modesty and unassuming
demeanor might strike some as unexpected.
although w elcome characteristics. Runge
has consistently demonstrated an ability to
manage a lot of responsibilities with the
highest degree of skill and professionalism.
Runge"s talents and work ethic, however,
come as no suiprise to his family and friends,
vv ho know of his childhood grow ing up in the
Texas hill country.
"My parents are both children of the
Depression and are really big on education,"
said Runge. "They were very insistent
on getting a good education and putting it to
good use. The\ never pushed me in
an\ direction in particular, but did, on occa-
sion, tell me that if I procrastinated too much,
they would."
Althousih Runae was not alwavs sure he
wading, Teaching, Caring
u anted to he a doctor, there \\ as strong pull in
his famils toward medicine — with se\eral
phvsician I'aniih members, including his
older sister and younger brother — both of
\\ hom also ended up in academic medicine.
Now as a diKtor specializing in cardiolog>.
Runge finds it amusing to reflect on his original
vision of becoming a doctor. ""When I first
thought about going into medicine, my plan
was to go into famiK practice in a small town
in central Texas w here my grandparents had
a ranch." he recalled. ""But in college, some-
what to my surprise. I became interested in
basic molecular biology research, and it w as
that interest that really led me to academic
medicine. That life wasn't \'ery compatible
with tamil\ practice in the central Texas hill
countPv. though."'
The directum his life has taken is quite
unlike the life of a family practice doctor in
central Texas. Although he wanted to attend
the University of Texas at Austin, Runge was
encouraged to look beyond the comforts of
familiarity and home for an education. His
parents' insistence that he li\e at home if he
attended LT. proved enough niotix ation to
send Runge to Vanderhilt University in
Nashv ille. Tenn.. where he studied biology.
Vanderhilt is where Runge met his wife
.Susan, an anesthesiologist. .She's put her
practice aside for now. concentrating instead
on being a full-lime mother. ""Susan and I met
in chemistry class." said Runge w ith a grin.
.After graduating from Vanderhilt in 1976.
Runge decided to continue his education
there and in 1979. completed his PhD in
Vanderhill's molecular biology program.
From there. Runge attended Johns Hopkins
University School of .Medicine, where he
received his .\H) in I9S4.
Since that time. Runge has thnveil in his
position as a physician and researcher,
devoting much of his career to the study of
vascular biology and clotting thrombosis.
"I'm interested in knowing how the blood
vessels work." he said.
UNC's long-standing reputation as one of
the world's leaders in thrombosis research.
the growing interest here in v.iscuiar hioloyv.
and the breadth of cutting edge research both
in the department and medical school are all
reasons that Runge decided tit come io
Chapel Hill. "UNC has a wonderful and well
desened tradition and reputation in thrombosis
research, and has great science throughout
the institution." he said. ""Although I hadn't
initially sought a position as chairman, the
strength of this department and of UNC and
the area were practically irresistible. Plus,
everyone I knew, including several former
UNC faculty members who were chairs in
Galveston. realK spoke ver\ highh of the
institution and area."
As the new chair of medicine. Runge is. in
part, responsible for setting the tone for
students hoping to enter the medical profes-
sion. He will teach on inpatient services in
areas of clinical medicine, including his area
of expertise, cardiology. ""I very much enjoy
teaching at different levels." he said. ""One of
our most important teaching roles as faculty
focuses on the approach to the patient. We.
and our students, must learn to evaluate
patients in a scientific w ay in order to consider
all possible disease processes and treatments
while never losing sight of the impoilance of
compassion and the phv sician-patient rela-
tionship. Helping medical students and hous-
estaff learn these lessons in today's more
hurried medical environment is a challenge
that we must address."
Runge plans to combine his scieiiiilic
instruction with an emphasis on profession
alism and respect for patients, their families
and coworkers in health care. ""The best
approach, in my opinion is lo leach interac-
tively and by example." he sav s.
Runge wants also to leach medical
students in the pre-clinical vears. focusing on
the application of basic science to the
practice of medicine. ""In the past. I have
taught in physiology and pathophysiology
courses on the heart and blood vessels, and I
hope to be do the same here." he said.
Along w ith his duties as a tacullv member
111 the School of Medicine. Runge will spend
a significant amount of lime with the mctlical
houseslall \\\n In lliice davs a '.'.cck. kuiii.'e
will attend a conlcieiice called Morning
Report and then answer questions at
bi-weeklv "Stump the Chair" sessions.
"The job of chairman is a truly daunting
task, particularly w ith the ever-changing
health care environment." he said. ""Today, it
is not only important to be involved in all the
traditional areas of academic medicine, but to
alw ays have an eye towards adapting to the
changing landscape. Thinking back about
some of the incredible chairs that I have
know n. as well as those w ho have preceded
me here, these indiv iduals somehow com-
bined teaching, clinical care and research in
their own lives and integrated these into their
departments. They not only led by example,
but also faced the administrative challenges
of managing a large and important part of a
medical school through challenging times in
academic medicine. Without question, this is
a much larger job than anv one person, and
we have a wonderful faculty at UNC and
div ision directors, all of whom have alreadv.
and continue to rise to the occasion."
Runge's relocation and new job mav seem
lo him like a breath of fresh air. but it is
Runge who will breathe new life into the
department of medicine. "I think we have to
lake a fresh look at medicine." he said. "Willi
the collective brain pow er of the departmenl
of medicine. I have no douhl thai if we are
w illiiig lo be miiovalive. lo lake risks aiul lo
persisi. we can make changes that will allow
all of us to spend more time on what we
entered academic medicine for in the fiisi
place — to do research, lake care of palicnls
and leach." D
Scholarship Established in
Honor of Harold Roberts, MD
BvBernadetteGillis
Sa\ ing ihank you lo one man never
meant so much to so many. In appreeia-
iii>n of years of support. Ron Neal.
MD, "75. an OB Gyn in Greensboro. N.C..
created a scholarship to help medical school
students in honor ol' Harold R. Roberts. MD.
".'^.'^. The scholarship endowment fund is held
at The Medical Foundation of North Caroli-
na. Inc.
"Harold Roberts was not onl\ a mentor to
me but also a father figure. Neal said. "E\er
since I was in medical school. I ha\e wanted
lo thank him. The most significant thing I
could to do was to set up a scholarship." The
Roberts Loyally Fund Scholarship was an-
nounced by Neal with Roberts standing at his
side at the Spring Medical Alumni Weekend
Banquet.
The need-based scholarship, named after
Roberts, will benefit medical students u ilh
llnancial need.
Ha\ ing come from disadvantaged back-
grounds, helping economically disadvan-
taged medical students would mean a lot \o
both Neal and Roberts. Neal said. "We both
know what it was like to staiggle. That's the
reason for setting up a need-based scholar-
ship." He added. "ll"s a way of helping those
like him and mvself."
It was Robeils' understanding of financial
struggles that led Neal to find a role model in
Roberts. "Hav ing lost my father a at \erv
voung age. it was easv for me to admire
him."
Neal worked w ith Roberts for three vears
before attending the school of medicine, first
as a technician and later as a graduate stu-
dent. "Dr. Roberts was personally interested
in my work and helped me realize my dream
of becoming a physician."
Roberts taught Neal many lessons in life,
including the importance of the being the
best at w hat you do despite your occupation
or background, said Neal. "I am certain that
Dr. Roberts and 1 share the belief that men
and women of character, intelligence and
commitment should be able to pursue c;u"eers
in medicine, regardless of economic circum-
stances."
]()
Hiimlil Rdhcrts. MD. left, learns of Ron iWcal's \c/iol(ir.\hip i;ifr.
The Harold R. Roberts Loyalty Fund
Scholarship will benefit one student each
year beginning in the fall 2001 . The scholar-
ship is one of .'i 1 Lovalty Fund Scholarships
awarded annually by the Loyalty Fund, the
unrestricted annual fund of medical school
alumni. A campaign is underway to endow-
all .^1 scholarships at a minimum of
$100,000. Rising costs, including a signifi-
cant tuition increase, make the case for en-
dowment. A story will appear in the next
Bulletin in regard to the Medical .Alumni En-
dow ment Campaign.
Neal said he is happv the scholarship will
benefit medical students w ith backgrounds
similar to his. "It's a wonderful feeling lo
know vou are helping others, and this is a
w onderful oppoiiunitv to help."
In addition to show ing his appreciation for
Roberts' infiuence. Neal said the scholarship
was established also to recognize Roberts'
contributions to the school of medicine. "Dr
Roberts is one of the medical school's great-
est advocates, and he's made a tremendous
difference."
Ri)berts has serv ed on the school of medi-
cine faculty as an internationally recognized
specialist in hematology and coagulation. He
was also granted the Distinguished Career
.Award for Contributions to Hemostasis by
the International Societv on Thrombosis and
Hemostasis. He w as honored w ith the Med-
ical .Alumni .Association's Distinguished
Serv ice .Aw aid earlier this year.
UNC Professor Endows
National Prize in Neuroscience
One of UNC's most distin-
guished researchers recenii\
endowed ii SlO.Ooi)
national prize to he awarded
annuall) tor an outstanding scientific
contribution to neuroscience.
Edward R. Perl. MD. Surah Graham
Kenan professor of cell and inolecuiar
ph\ siologs said he endow ed the prize
to draw attention to UNC"s strengths
in neuroscience and pa\ tribute to the
uni\ersity
"The prize allow s me to acknow I-
edge the uni\ersit\ for the opportuni-
ties it has gi\ en nie." he said. "The prize
would bring to the campus on a yearl\
basis major contributors in the field to
receixe this aw ard. gi\e a lecture and
interact w ith people here.
"The prize would be a legacv of nn
ha\ ing been here and would help call
attention to the institution and our
strength in neuroscience."
Perl said he hoped the prize would
be awarded for an outstanding disco\ -
cry or seminal insight, rather than to
commemorate a lifetime bod\ of work.
"The selection committee would
choose from the broad field of neuroscience
ranging from de\ elopment to molecular
mechanisms to integrative function." he said.
"It is m\ specific w ish that the prize should
not focus on the same area in successive
\ears. The concept is to recognize people
aid R. Perl. MD
ind
w ith fresh and current contribution
make them aw are of UNC."
Perl, who received his medical degree in
1 949 fn>m the Uni\ ersily of Illinois at Chicago.
tv\ice served as acting head of the L'ni\ersit\
of Utah's physiology department. Recruited
to Carolina to build up the uni\ersit\ s
strength in the neurosciences. Pei 1
served as chairman of |ilivsiologv from
1971 to 1989.
A founder and acting president w hen
the Society for Neuroscience w as start-
ed in 1969. he was awarded that group's
1998 Gerard prize for outstanding con-
tributions to the field.
Perl's wiirk in pain mechanisms has
been highlv influential. He was the first
to document the existence of nocicep-
tors, sensorv fibers speciallv activated
bv tissue damage and their relation to
the sensation of pain. He
continues to explore the biological
bases of pain sensation.
Nearing completion on campus
is a S3()-million Neuroscience
Research Center, headed bv William
Snider. MD. a pioneer in the action of
nerve grovMh factors, proteins thai help
neurons grow. Perl helpei,! rcciuil
Snider to UNC.
"His nociceptor work has had an
enormous impact on modern pain re-
search." Snider said of Perl.
"There are nov\ literallv dozens of
laboratories, as well as biotechnology and
pharmaceutical companies, studying the
molecular characteristics of these neurons
w ith an eye toward developing novel pain
therapies." D
Californian wins first Perl-UNC Neuroscience Prize
.\ California researcher became the first
w inner ot a national prize endowed bv a
distinguished scientist at the University of
North Carolina at Chapel Hill. The prize, to
be awarded annuallv. recognizes outstand-
ing scieniiflc contribution to the Held of
neuroscience.
The SIO.OOO Perl-UNC Neuroscience
Prize goes to Oav id Julius. PhD. professor
111 cellular and molecular pharmacologv at
ihe I ni\i.-isil\ cil { '.ilitiirnia-San IraiKisco
School of Medicine.
Julius discovered the nerve cell mole-
cule that mediates responses to capsaicin,
the active ingredient in hot peppers. The
capsaicin receptor. VRl. also is responsi-
ble for the transmission of noxious heal
sensations.
I hat discover) four vears ago. and
Julius" subsequent studies, build on the pi-
oneering research of neurophvsiologist |-d-
ward k Perl. Ml). S.ir.ih Giahaiii Kenan
professor of cell anil molecular phv siologv
at UNC's .School of Medicine,
Julius said he was lionoieil lo have le
ceived theavsard.
"I lake great pride and pleasure in being
named the recipient of the first Perl-UNC
Neuroscience Prize." Julius said. "Ol
course, this prize is made possible through
the generosity of Fid Perl, but it also rellecls
his pioneering studies in the area of noci-
ception and sensorv iieunin liinclinniiiL' "
Research
Briefs
Research shows radiologists
will need different programs
for digital mammography to
work best
For doctors to take best ad\ antage of new
digital mainiiiography and possibly saxe
more women from breast cancer, companies
that manufacture the technology need to cre-
ate new. more sophisticated computer pro-
grams. University of North Carolina at
Chapel Hill scientists say.
That's because a team of researchers led
b\ Htta Pisano. MD. professor of radiology,
has found that radiologists prefer different
kinds of images for c\ aluating different types
of breast tissue ahnonnalilies.
""Before v\e did our study, we thought that
a ceilain type of lesion and a certain kind of
breast density, for example, would require
only one type of processing." said Pisano.
also chief of breast imaging and a member of
the UNC Lineberger Comprehensix e Cancer
Center. ""Now. we think displaying images
w ill be more complicated. To get full use out
of digital mammographs' machines, compa-
nies are going to have to put some resources
into optimizing images for different tasks."
■An image processing program that reveals
calcitlcatiiws in the breast will be different
from one that helps doctors evaluate those
calcifications once they've been found, she
said. The same holds true for cancerous
breast tumors.
A report on the latest research appears in
the September issue of Radiologx,. Besides
Pisano. authors are Elodia B. Cole, reseaich
associate in radiolog\ : Stacey Major, fomier
research assistant in biostalistics: Shuquan
Zong. graduate research assistant; Bradle\
M. Hemminger. senior research associate in
radiologx ; Keith E. Muller. PhD associate
professor of biostalistics; and 27 co-authors
iVoni the International Digital Mammogra-
phs De\ elopment Group. The latter is a con-
sortium of radiologists from UNC. Harsard.
Johns Hopkins. Duke and other uni\ersities.
■A companion report in the September issue
o{ Radiographics contains images from the
studs.
The lescarch insohed showinc imaees
Worn 2S patients w ith various known breast
abnormalities to 12 radiologists who com-
pared digital images from three different
commercially asailable machines to tradi-
tional film mammograms from the same pa-
tients. The physicians were asked to decide
and record which images they preferred in
making diagnoses. Manufacturers were Gen-
eral Electric. Fisher and Trex.
The challenge for General Electric and the
other companies will be to create new. more
sophisticated computer sitftware that takes
into account what radiologists beliese pro-
vides the most helpful pictures, the ph\ sician
said.
The National Cancer Institute, the U.S.
Amiy Medical Research and Material Com-
mand and the Canadian Breast Cancer Re-
seiuch Initiatis e supported the research.
For more information, see lutp://w\vw.
iinc.edii/ne\\s/newssen'/resecircli/piscmoH3l
on. htm
Camera to detect early signs
of lung cancer; tests at
UNC seek people at risk
for disease
Physicians at the Ihiisersity of North Car-
olina at Chapel Hill School of Medicine are
seeking people at high risk for deseloping
lung cancer to participate in a studs' aimed at
detecting early signs of the disease.
■"We are looking for people svho has e a
prior history of early-stage lung cancer, head
or neck cancer, smokers os er age 35 and
smokers svho base had relatises svith lung
cancer."" said Patricia Risera. MD. assistant
professor of medicine and a member of the
UNC Lineberger Comprehensise Cancer
Center. ""Our hope is that sve ss ill be able to
detect cancers at a much earlier stage svhen
sve knoss ihc chance of treatment success is
better."
The study, w hich is in collaboration ss ith
scientists from the National histitute of Ens i-
ronmental Health Sciences, involves a cam-
era de\ ice called LIFE, for lung imaging
fluorescence endoscope.
UNC phs sicians base been using the LIFE
unit, ss hich is approsed bs the U.S. Food and
Drug Administration, for more than a year to
detect pre-malignant or malignant changes
inside the lungs. UNC is the only facility in
North Carolina svith the device.
Created in Vancouver. Canada, by Xillix.
the LIFE bronchoscope is an improvement
over conventional bronchoscopy. X-rays or
sputum tests. It uses red or green light svaves,
causing normal cells to appear bright green.
Abnomialities. such as pre-cancerous lesions
and tumors, shoss up as sarying shades of red
orbrossnish red.
"'It is more sensitise than the traditional
white-light bronchoscopy for precancerous
lesions." Rivera explained. ""'With the svhite-
light method, even an experienced hroncho-
scopist can miss a lesion."
This improsed sensitivity means physi-
cians can encourage patients svith early signs
of cancer in their lungs to adopt ness and
healthier life habits.
■"By catching tumors that are precancer-
ous, we can make intersentions and also en-
courage patients to stop smoking."' Risera
said. "'We beliesc that some pre-malignant le-
sions may regress if patients stop smoking."
For more information, see http://www.
iinclicalthcare.org/medsys/news/new.sreleases/
ne\[\release.cfi}i/rele(ise=life_l'>romhoscope.
Iitnil
Hearing loss a threat to
children who survive 'stiff
lung' condition at birth,
UNC physician finds
Children ss ho surs ise a condition at birth
in which their lungs are too stiff to saturate
their blood w ith enough oxygen mas be at in-
creased risk for progressise hearing loss and
need perii)dic hearing tests, according to a
University of North Carolina at Chapel Hill
physician.
Newborns ssiih the potentialls life-threat-
ening condition called persistent pulmonary
hvpertension. or PPHN. usually are put on
mechanical s entilation s ia a breathing tube.
Surs is ors of PPHN need folloss -up moni-
toring ss ith periodic hearing tests, even if
standard auditory testing in the first ss eeks of
life prose normal, according to Wendell G.
■^arbrough. MD. assistant professor of oto-
lan, ngology and head and neek siirger).
in the United States, about ID.IMM) babies a
year are bom \\ ith this disorder.
Writing in the .August issue of Airhivi's of
Otoliii-Mifiology. ^'arbrough makes his point
describing the ease of a child with dekiyed-
onset hearing loss
'".As a neuborn. this child had sur\ i\ed
persistent pulmonar\ hypertension. He was
treated in neonatal intensive care and after
discharge from the hospital had done fine on
regular pediatric examinations." ^'arbrough
explained. "He also did well on standard de-
Nekipmental tests at se\en and 1.^ months.
These showed nomial response to sound, but
did not include fomial audiologic testing.
"But w hen he was about 3 years old. his
parents brought him to our clinic because
they were concerned that the child might
ha\e poor hearing. They had noticed the dif-
ference in speech dexelopment between their
older child."
The parent's concerns were justitled. The
child communicated w ith poor articulation,
and hearing tests resealed moderate to se\ere
bilateral sensorineural hearing loss. Auditor)
simctures w ithin his ears essentially w ere not
detecting sound signals for ner\e transmis-
sion to the brain.
"We titled him w ith hearing aids and sent
him to speech pathology for a fonnal speech
and language evaluation. He had a vocabu-
lary of about 50 words, compared with 900
words ty pical of 3 y ear olds." Varbrough
said. "Auditory comprehension, expressive
communication and total language score
w ere consistent w ith a one-year delay in
s[X'ech and language skills."
The boy was enrolled in speech therapy
and followed by an audiologist for hearing
e\ aluation and refitting of hearing aids.
\N hen he was seen again in the clinic six
months later, his viKabulary had increased to
2f^i) words. But tests demonstrated a progres-
sion in hearing loss.
In his journal report, 'i'arhidugh acknowl-
edged a growing body ot data supporting a
link between PPHN. its medical treatment
and hearing loss.
"The issue is clouded to some degree be-
cause a lot of these children were on different
types of ventilation support or on drugs such
as gentamycin |an antibiotic], which have
been associated with hearing loss." he said.
"But I think it's becoming clearer that the un-
derly ing insult is not necessarily what we do
to the child but the disorder itself. PPHN."
For more information sec
htip://\vww.imchealthcare.orf>/mfdsys/ue\\s/
newsrelcases/ne\\srelease.cfm/release=sliff
_luni;.liinil
New protein key to cell
shape and movement;
has implications for
cancer, pregnancy, brain
development, wound healing
.A protein discovered by scientists at the
University of North Carolina at Chapel Hill
appears to play a key role in delennining the
shape of cells and allow ing them to move.
The newly identified protein, called pal-
ladin. is being explored for its inlluence on a
number of biological processes, including
the invasive spread of cancer, wound healing,
brain development and the implantation ot
the embry o in the uterus.
"I think it may be critically involved in
even more biological functions." said Carol
A. Oley. MD. assistant professor of cell and
molecular physiology. A report of the dis-
covery, co-authored by Mana M. Parast. MD.
of the University of Virginia, was published
in the Aug. 7 issue of the Journal of
Cell Biology.
Otey said the new protein was named after
Palladio. the intluential I6th-ccnluiy archi-
tect. Palladin appears to be quite involved in
the architecture iif cells, specifically via
the actin cy toskeleton. a polymer protein
complex that ihovkIcs much of the basis for
cell shape.
"Cells have a shape that is ivlalctl to iheir
luiictioii." Otev explained. "A good example
of specialized cell shape is the neuron. They
must be very long and skinny to allow the
nervous system to lunclion. .Another exam-
ple is epithelial cells, including skin cells,
which bind tightly to one another lo form a
continuous sheet."
.According to Otey 's findings, palladin be
longs to a small group of cy toskelelal atllic-
sion proteins that seem to prov ide molecular
'glue" for maintaining cellular shape and for
the attachment of cells to one aiuuher v ia
their plasma membranes. For example, fi-
broblasts are spindle-shaped cells involved in
connective tissue and collagen tbmialion and
also are crucial to wound healing. In these
cells, palladin is concentrated near attach-
ment points to the plasma niembranc.
On the other hand, palladin is abseni. not
expressed, in some undifferentiated cells;
that is. in cells which haven"t achieved their
genetically predetermined shape. Thus, the
protein is absent in precursor stem cells.
"So this indicates that palladin play s a role
in fomiing the new cy toskeleton of cells that
are beginning to differentiate and take on
their specialized shape." she said.
.According to Otey. an exciting thing about
palladin is its presence in different torms.
different molecular w eights.
"In many different types of cells, one
lorm of palladin may be necessary for tight
adhesion and another for migration, or move-
ment."' she said.
She noted that a heav ier fonii of palladin is
more highly present, or expressed, in
metastatic cancer cells — tumor cells that
spread beyond their point of origin.
This research is supported by grants from
the National Institutes of Health.
I-oi more intormation see hup:
//\\w\\.:uneiiealtiuare.org/meds\s/news/news
releases/new sii'lease.cjin/n'lease=ixilladin.html
23
Development
Notes
Tile-painting endeavor
to raise money for
N.C. Children's Hospital
A unique parlnership between the
N.C. Children's Hospital and a Chapel
Hill business will raise money for the
liospiiaTs pediatries program.
"Hands and Heels for Hope" is
a pri)gram eo-sponsored by Paint the
Earth, a paint-it-yourself eeramie studio
in Chapel Hill, and The Medieal Founda-
tion ol' North Carolina. Ine. Paint the
Earth is ottering a special tile-painting
opportunity that will give artists long-
term recognition and pro\ide financial
support to the N.C. Children's Hospital.
Through "Hands and Heels lor
Hope." artists can paint 6-inch square
tiles that will be permanently moLuited in
the lobby of the new N.C. Children's
Hospital. The cost is $25 for one tile or
,S40 for two tiles. Proceeds benefit the
N.C. Children's Hospital.
Paint the Earth will donate
all tiles and supplies, and will gla/e and
fire the llnished works.
Indi\iduals are encinuaged to \isii
Paini ihc Harlh at ."^16 \V. Franklin .St.
— |usi be suic to icll a studii) staff mem-
ber the purpose of your \ isit. Handprints
and footprints of children are suggested
figures to paint, but any tasteful message
or art is welcome.
The ne.xt tile-painting fundraiser will
be held Fri, Dec 8, at the Medical Au.xil-
lary Holiday Bazaar in the lobb\ of the
N.C. Neurosciences Hospital.
150 Attend Fall
Co-Founders' Meeting
Nearly 150 people attended the Fall
Co-Founders' Meeting held Nov. 1 I and
hosted by The Medical Foundation of
North Carolina. Inc. The Foundation held
the e\enl al the William and Ida Friday
Conlinuing Education Center for those
who have contributed more than SI. ()()()
this year.
Co-Fininders' Club President Daxid
Rendleman. MD '70. presided over the
meeting v\hich focused on women's and
children's programs at UNC. A sneak pre-
\ iew ()f the new N.C. Children's Hospital
was presented by .Alan Stiles. MD. chair
of the department of pediatrics. (For more
inlormalion about the new N.C. Women's
Mike Bticy. left, a UNC
senior and head of last year's
UNC Dance Marathon,
presents a check for $70,000
to Eric Mimson. UNC Hospitals
president and chief executive
officer { second from left).
Scarlet Cardwell. director of
the department of social work,
and Alan Stiles. MD. chair of
the department of pediatrics.
The Dance Marathon is on
aimiial fundraising eveni
organized In UNC students to
benefit the N.C. Children's
Hospital. Dance Marathon
2001 will he held in Fchniarx.
and Children's hospitals see page 4.
Program highlights included the fol-
lowing presentations by UNC .School of
Medicine faculty members:
"The Center for Maternal and Inlanl
Health." by Ken Moise, MD. professor
and division chief of maternal-fetal medi-
cine
'Cutling-Edge Techniques of Intrauter-
ine Therapy." by Nancy Chescheir. MD.
professor, department of obstetrics and
gynecology
"Prenatal Cardiac Diagnosis." by John
Cotton. MD. assistant professor, depart-
ment of pediatrics
"Approaches to Congential Heart Dis-
ease." by Mark Bleiwiess. MD. assistant
professor, department of pediatrics
Co-Founders' meetings provide donors
information on issues facing the School of
Medicine as well as new research and
technology.
24
Alumni
Notes
20s
Uni\ersity of Soiiih Carolina in
Charlesiiin. SC.
Herman F. Easom, MD "27. li\es in
Wilson. N.C. and works pari lime ai
chest clinics for tuberculosis. In 19M7. he
lost his uife: the two had no children.
40s
George Md^eniore. Ml) "46, would
like lo know how is lellow classmates
are doinj:. McLeinore continues to prac-
tice medicine at his cardiolog\ practice
in New ^'ork Cit\.
60s
.|(ie (iriffin. MD "68, retired in August
Irom the .Medical College of Georgia as
professor of medicine (gasiroenterolog\ i
after 2.*^ \ears on the facult\. He plants to
enter prisaie practice in .Augusta. Cia.
70s
I)a\id H. Hopper. .Ml) "76. president of
Total Life Famil\ Practice Center. Inc.
and Bill Harden. MD 77. from
Bluefield. Va.. wrote "we (recentl\)
worked lor eight da\s in the isolated aiul
rehcl-controlled lerriiones ol the Nuba
.Mountains and Blue .Nile districi ol
.Southern .Sudan, .\lrica." The two treal-
eti .^.000 patients lor malaria, worms.
d>senler). iropic.il skin ulcers anil
numerous other prohlcms. ID see
photos ol the trip check ihe web siie at;
h 1 1 |i : //c o m m u n I 1 I e s . m sn.com/
missionlosLidan
Tomm> Pope. .Ml) "78. was recentl\
promoted as professor and chair ol ihe
deparlmeni ol radiologv at the .Meilicai
80s
.Vngela Kendrick. Ml) "82, is a pediairi
anesthesiologist at the Doernbechei
Children's Hospital in Portland. Or. Sh
and hei" husband. Biad. unite ainonc
who \isits Portland to stop b> for a \isii
.And. bring some barbecuel
Scott L. Raniey. .Ml) '81. is duel of
inter\entional radiology with Ba\
Radiology Associates. PA in Panama
City. Florida. His email address is
SLR.'Sac? aol.com
Teri Rummans. MD '81. Ii\es in
Rochester. Mn. where he works in the
department ol' ps\chiatry at the Ma\o
Clinic. He was recentK elected presideni
of the staff for 2001.
90s
Ibrez Handukwala. .Ml) '^7. is a mem-
her of the Hmor\ L'ni\ersit\ Hospital
ileparlment of medicine facult\. He plans
lo maiT\ Claire Parker. MD '47. who is
currently a fourth-\ear resident in oh/gyn
at Emory Uni\ersii\ Hospital.
Michelle Kilbv. MD '90. is an assisianl
jirolessor in pediatrics at the rni\ersii\
of .Alabama. She also is the medical
director ol the child abuse team and
reccnth recei\eil her masieis in public
health. She and her husbaiul. Michael,
have two sons.
|{r>aii Ne>Mirtb. MI) ••)!, pissed ihc
.A\er Board of Cosmetic Surgery in .April.
Nevwirth lives in Hickory. NC. with his
wife and four children where he works in
a private oral, ma.xillofacial and cosmetic
surgeiA practice.
(;ardiner Roddey. MI) '•>(!, and Patty
Roddey. .MD "•)(). live in Charlotte. NC
w ith their sons Rich. 7. Idi. 2 and daugh-
ter Lvle. ."^ monlhs. Pallv practices 2 1/2
davs per week. Ciardiner. although he
works king hours, still finds nme lo plav
some soccer and basketball.
Melinda T. Wyatt. MI) '93, and her
husband Rick, recent l\ welcomed
Nicholas Tav Kir Wvatlt to iheir family
this year. Melinda is currenilv in inivaie
practice in Raleigh. NC.
Deaths
Re\ Speers, MD, House Staff. 57-'6I
25
2000-2001 Loyalty Fund Scholars
The Loyulu Fund iiiilialed iIk' Merit
Award program in 1966 with a modest
stipend to six students. In the late 1980"s the
Medical Alumni Association developed a
strategic vision to promote broader and high-
er levels of alumni support. Increasing pri-
vate gilts enabled the number of scholarships
to grow from 20 in 1 993 to 5 1 currently, each
ccnering full in-state tuition. The awards for
2()()0-2()()l are S3. 300 e.\cept for Allied
Health Sciences, which are $ 1 .500.
Merit Awards - ,Aii estimated ten awards
are made for highest honors during MS I. II
and III. (MS Ills to be detemiined. )
Four-Year Scholarships - Twenty-four
students are supported. Si.\ awards to MS Is
for four years based on academics, leader-
ship and financial need. Two are designated
for MD/PhD students.
Fourth-Year Generalist Scholarships -
Fi\e aw aids to MS IVs who ha\e committed
to a generalist residency program.
First-, Second- and Third-Year
Scholarships - Three one-> ear aw aids for
each class based on academics, leadership
and financial need.
Allied Health Sciences - Three aw ards
for students to be selected b\ the Department
Chair.
Jessica Bailey
Lindse\ Baker
April Blue
MS III
Allied Si wiKfs
MS l\
Foiii-Ycai
Theodore Brissoii
MS II
One-Year
Jeiiniler Bushman
Martin Butler
MS 1
MS II
MD/PhD
Merit
^^ja
Jennifer Chancellor Jerome Chen
.1/5/' MSI
One-Yetir OiieA'eiir
Lisa Cohen
Heather Crouse
MS 1
MS III
Four-Year
One-Year
Donna Culton
C urios hherl
MS III
MSI\-
MD/PhD
FiHir-Year
Stephanie Talk
MS II
F<uir-)'ear
Kelly Fogleman
MS 'll
One-Year
Matthew Foster
MS III
Four-Year
Lee Gray
Jamie Green
AlludSciciuc
w
Duncan Hill
\oah Hoffman
MS III
MS III
OiuYciU
MlVI'hD
v%
O
^
; ' >
r^fei
V .
Rodney Look (
Chad McCall
A/S /\ '
l/.V /
(hH-)iOr
MD/I'hli
Miihail Ro\intlial Jonathan Roiilli
\t\ III MS III
Ml) I'lil) h'Ki-Ycai
>-^^
Llizahelh (iiukian Slacy Haponik
Mlud Scumc^ .MS I
hour-Yiar
Jennifer Hunter
MS III
Mem
Dallon McLean
MS II
Miiv
Shaida Ryan
MS III
i, mi -Year
Jt^\
Rebecca Sands
MS III
OiH-Yan
Gavin Henderson
MS II
MD/Phn
Michelle Hernande:
MS III
I'/'/av Krishnamiirthy Milele Kudumn
MSI MS II
(>iu)cui Oiu )c,ii
Shannon Sawin
MS l\
I. nil -Yen
I 1
Jason Merker
An up Parik
iMtonia Roach
MS III
MS 1
MS l\
MD/PhD
ilnc-Ycai
h>lll )cui
( harle
\ Smith
Rishi S\al
Charles Toulson
Ixivanya Miidya
\(iin \o
Rehccca Walk,
\/S l\
MS II '
MS l\
MS III
MS n
MS 1
DihYc
III
I-niii-Ycar
OiicYiiir
Merit
loin Year
h.iii Year
Sara Woods
MS I
hour- )c<ir
11
Loyalty Fund Campaign
Loyalty Fund Budget FY 2000-0:
$705,000
Student Scholarships and Programs
S22(i.ll(l()
Communications
SI 26.00(1
Medical Alumni
Distinguished
aching Professorship
S50.000
lealth Science
Library and
Icchnology Support
S50.b00
Area Campaigns
Atlanta
George W. Cox. .\1.D. '66 Cluiii
Buncunibr County
E^ienilcy D. Jeftries, M.D. 'S."; Cliuii
Durhani/Orange Counties
W. Woocliou Burns. Jr.. M.D. ■6'-) Co
Cluui
\\ Benson .McCulcheon. Jr.. M.D.
IIS Co Clhiii
Forsjth County
Richard C. Wor'f. M.D. 'VS Cluiir
Cuiiford County
Drew A. Jones. M.D '^l CoCliuir
Leigh H. Jones. KLD. '90 Co-Chuir
Mecklenburg County
Rob\n StacN-Humprhnes. M.D. 'S?
Co'chiui
Bradlev K. Weisiier. NLD. S.S Co-
Chan '
New Hanover County
John ,\L Herion. M.D.''S.^ Clhur
Wake County
H Chllon Pailers.ni til. M.D, '74
Reunion Campaigns
Class of 1445
John R, Pender 111. M.D. Chair
G. Robert Clults. M.D.
A. Robert Cordell. M.D.
Class of 1950
John .A. Kirklarid. .M.D. Cluiir
Frederick O. Bowman. Jr.. M.D.
W. Grimes B\erlv. Jr.. M.D.
EluoodB. Cole\. M.D.
John T. Dees. m'.D
Laurence B. Leinbach. .M.D.
John L. McCain. M.D.
Lewis S. Thorp. Jr. M.D.
Charles R. Vernon. M.D.
John L. Walters. M.D.
Class of 1955
John W. Pousi. M.D. Cluiir
.Medical Alumni .•\lumni Outreach
Endowment Fund 5115.000
$25,000
•Funds raised in cvijcss <>t hiidj:i.-i dccrcasL- ihc piTtctilai-c
Har\cy Adams. NLD.
Julian S. Albergoili. Jr.. M.D.
Robert G. Brame, M.D.
Ralph E. Brooks. Jr.. M.D.
Walter E. Deyton. NLD.
PreslcN Z. Dunn, Jr.. M.D.
- J. Eugene Glenn. M.D.
Ira D. Godwin, M.D.
James W. Haves 111. M.D.
Charles L. Herring. M.D.
William D. Huftlnes. NLD.
SamuelG. Jenkins. Jr., M.D.
Samuel B. Jovner. NLD.
A. Smith Lineberger. Jr.. M.D.
William L. London IV, M,D.
Llovd C. McCaskiU. M.D.
Andrew C. Nliller III. M.D.
J. Th.iddeus NIonroe. Jr.. NLD.
G. Ir\in Richardson. NLD.
C. William Rogers. NLD.
Roben L. Summerlin. Jr.. NLD
G. Reginald. Jr.. M.D
Class of l%n
Elliott Solomon. NLD. Clmir
Jefferson D. Bulla 111. M.D.
John R. Dvkers. Jr., M.D.
Gerald W Fernald. M.D.
Robert H. Hackler 111. NLD
James R. Harper. NLD
Falls L. Harris, NLD.
E. Carwile LeRov. M.D.
J. Gray McAllister 111, M.D.
K. Franklin NIcCain. M.D.
William N. Nhchal. Jr.. NLD.
Cecil H. .\e\ille, Jr.Nl.D.
Duncan S. Owen, Jr.. NLD.
Robert B. Payne, NLD.
Jerrv Nl. Petty, M.D.
Jean R. Poirier, M.D.
Elizabeth V. Raft. M.D.
Hilliard F. Seigler, M,D.
Robert F. Sloop. Jr., M.D.
John C. Tavloe, NLD.
P Bun Nca/e\. NLD.
NLD. Chan
NLD.
NLD,
Class of 1965
VVilliani F. Sasers
James O. Burke. Jr
Takev Crist, M.D.
Robert V. Fulk. Jr,
Charles R Graham. Jr.. NLD.
Alexander C. Hattawav ML M.D.
Howard Holderness. Jr.. M.D.
Joe R Hurt. M.D.. Ph.D.
Richard E. Lassiier. NLD.
Gordon B. LeGrand. NLD.
JohnB. Shinn. NLD.
Williamson B Strum. M.D.
Class of 1970
David A. Rendleman 111. NLD. Chair
H. Clifford Baggeii. Jr.. M.D.
Jerrx C. Bernstein. NLD.
Daniel L. Crocker. Jr.. NLD.
Charles E. Crumley. NLD.
H. Shelton Earp lli. NLD.
James O. Goodwin. M.D.
C. Brvan Koon. Jr., M.D.
Edward A. Norfleet, M.D.
T. Reed Underbill. M.D.
Class of 1975
Hoke D. Pollock. NLD. Chair
Julian C. Brantley 111, NLD.
Samuel L. Bridgers II, M.D.
Dallas C. Craven, Jr., M.D.
Richard F. Fox. M.D.
Donald G. Gregg, NLD.
Thomas Higgins. NLD.
David S. Lennon, NLD.
Howard A. McNLihan. NLD.
Michael W. Meriwether. NLD.
Frank H. Morets. M.D.
Dan A. Myers, M.D.
W. Ronald Neal. M.D.
Marshall H. Odom. NLD.
Charles J. Parker, NLD.
H. Wonh Parker. NLD.
James E. Peacock. Jr.. NLD,
Wanda L, Radtord. NLD.
Carol B. Teutseh. NLD.
E. Brooks Wilkins. M.D.
Kenneth H, Winter, M.D.
Class of 1980
Sandra K. Haiglei. NLD Chair
Class of 1985
James W. Ledeier, Jr., M.D. Chair
Bernard T. Eaton, M.D.
Margaret K. Fikrig, M.D.
Catherine G. Fuller. M.D.
Susan C. Hadler, M.D.
David V. Janeway, M.D.
Margaret G. Johnson, M.D.
Peter M. Jordan. M.D.
Theodore C Kemer, Jr.. M.D.
John A. Kirkland.Jr.M.D.
James E. Manning, M.D.
Terry A. Morrow. M.D.
Joel E. Schneider, M.D,
S. Patrick Stuart, Jr., M.D,
Sherrie E. Zvveig, M.D.
Class of 1990
JohnE. Baiklev. M.D. Chair
John T Atkins 111. M.D.
Benila F. Banks. M.D.
L. Lorraine Basnight, M.D.
Eh/abcth D. Bell.\l.D.
VV Lee Bell, NLD.
Catherine L. Cooper, M.D.
Wilham De Araujo, M.D.
Mark T Hooten, M.D.
HaiTison A. Latimer, M.D.
Lori B. Lilley, M.D.
Garv B. Loden. M.D.
Wanda K. Nicholson, M.D.
Crvstal J. Pettiford-YeldelL M.D,
Eus;enia B. Smith. M.D.
Murphy F. Townsend III. NLD.
.Anne M. Tra\nor, M.D.
Craia Wierum, M.D.
John^H. Wood. M.D.
Mark W. Zinimemian. M.D.
Class of 2000
Stuart NL Hardv. NLD. Co-Chair
Shawn B. Hocker. .M.D. Co-Chair
Christopher G. Brow n
Troy A. Bunting, M.D.
KeliiG. Coop. M.D.
Timothy W. Dancv, M.D.
Cescili A. Drake. M.D.
Leslie R. Ellis, M.D.
SonjaT France. M.D.
S Brett Hea\ ner
Tracy R Jackson. NLD.
Ke\mNlLee, NLD.
Kimberh S. Levin, M,D,
Susan L. Mareelli, M,D,
Justin .A. Mutch, M.D.
Stephen W. North, M.D,
Nerissa NL Pnce. M.D.
Douglas D. Rockacv. NLD.
Karen B. Stit/enberg. NLD.
T.i\lorH. Stroud, NLD.
Report to Donors
Dear Mt'dical School Alumnus:
It is uith sincere thanks and apprecia-
tion that I report to \ou that t'lseai year
1499-2()()() (July-June I was another
record-setting year for alumni i2i\ing to
the UNC School of Medicine and UNC
Hospitals.
Almost 50 percent of medical alumni
naiionall\ contributed a total of S2.2 mil-
lion to benefit UNC School of Medicine
and UNC Hospitals. Of this amount.
SI. 5 10. 000 was restricted to support
much-needed professorships, fellow-
ships, lectureships and other important
programs.
The remaining S69().0()0 was con-
tributed b\ ?<9 percent of all alumni to the
l.o\alt_\ Fund, the unrestricted fund that
pro\ ides support where no other funding
sources are available. It would take an
endowment of SI4 million to generate an
annual income of S690.000. This illus-
trates the significance of alumni support
in the life of the UNC School of Medi-
cine.
The listing that lollows includes the
names ot all alumni who made contribu-
tions to an\ Medical Foundation account
between July I. 1999 and June .^0. 2()()().
Names in bold t\pe recognize alumni
who conlribulcd at the SI. 000 level or
above. Names in italics recogni/e alumni
w ho gave SI 0.000 or more.
Continued alumni participation in the
l.ovally Fund Campaign plays a pivotal
role in helping to determine the qualitv of
programs that the UNC School of Medi-
cine is able to offer its students and fac-
ullv each year. Thank you again tor your
generous support of all programs at your
alma mater.
Sincerely.
June M. McNcci: Asslsttint Dean
and Vice Picsidcni.
The Medical imuulaluiu af
Siirlli Can lima. Inc.
PS. Please notify The Medical Founda-
tion at (8(K)) 962-2.54.^ of any corrections
to this list. We have matle evcrv cllorl
tor accuracy.
Hoiuir RoW Of Alumni Di)iK)r;
1999-2(HH)
Sl.OOO-Sy.yw doitius ill, pnnttil in hohi
$IO.O(HI or more iiiv piinhcl in hold Uii/iix
CL.ASSOF i^z.";
Number in Class: 2
Percent Donors: 50.0 *>
Herman F. Easom. M.D.. WiNon. NC
CL.A.S.SOF 1924
Number in Class: 2
Percent Donors: 50.0 'r
\ancc T .Alcvander. M.D.. Da\idMin. NC
CI..\,SS()F 14.M
Number in Class: 8
Percent Donors: 25.0 ^t
Ralpli B. Garrison. M.D.. Hamlet. NC
J. .\. Whitaker. M.D.. Rocky Mount. NC
CLASS OF 19.^2
Number in Cla.ss: 5
Percent Donors: lO.O'^c
Georjie P Rosemond. M.D.. Laneansler. PA
CL.ASSOF 19.U
Number in Class: 4
Percent Donors: 50.0'r
William B. Patterson. ,\I.D.. Wailuku. HI
Jean R. Sutler. M.D.. Chapel Hill. NC
CL.ASSOF ly.^.s
Number in Class: 4
Percent Donors: 25.0 'i
Jiilien H, Meyer. .\I.D.. Roanoke. V.A
CL.ASSOF 14.^6
Number in Class: 12
Percent Donors: ISM'^c
l.andis P Milchell. M.D.. Spindale. NC
Laura R. Venning. Ml:).. Ctiapel Hill. NC
.\nnie Louise Wilkerson. \LD.. Raleigh, NC
CL,\SS()F 19.^7
Number in Class: 5
Percent Donors: 20.0'j
W. .Skellie Hunt. .|r.. NLD.. W ilniinnton. N{
CL.ASSOF I9.V;
Number in Cla-ss: II
Percent Donors: }()A'"c
Jesse B, Calduell. Jr., Ml),, (lastonia. NC
Henry T. Clark, .In, .NLD., Chapel Hill, NC
l.duin .A. R.isberrv. Jr.. Ml),. Wilson. NC
Pearl It Sehol/. MI). Balliniore. Ml)
CI ,\SS Ol 1940
Number in Class: 2.^
Percent Donors: .V).l'r
Inez W Fliod. M I ) . CliarloHe. NC
J..hn B Ciraham. M I) . Chapel llill, NC
Henry C C.uynes. Jr. MI),. Rockwall. T\
Joseph \V, K.ihn. MI). Fr.inkhn. NC
Robert K. Kirkman, M.I)., Key Biscayne, KL
French H. McCain. .Ml),. Bloonilleld Hills. Ml
George B. Patrick. Jr. Ml). Silver Spnni;. .Ml)
John L Ranson. Jr. Ml). Charkuie. NC
John H Woh/. Ml). Ch.irlone. NC
CL,\SS()F 1941
Number in Class: 15
Percent Donors: ii.i'e
Robert M. Hall. M.D.. Raleigh. NC
Jack Hughes. M.D.. Durham. NC
Claude Lowi") Pressls. M,D.. Charlolle, NC
Carllon C., Walkins. M.D . Charlolle. NC
Ernest H. Velton, M.D., Rutherfordton, NC
CL.ASSOF 194:
Number in Class: 23
Percent Donors: 26.1 'r
Jerrv H, .Allen. M D,. Springfield. MO
Frederick A. Blount. M.I).. Winsion-Saleni. NC
John B. McDevitt. M.D.. New >ork. NY
George W. Plonk. M.D.. Kmgs Mountain. NC
William Tenenblatl. Ml).. Lake Worth. FL
R, B Williams. Jr. Ml),. Wilmmglon. NC
CLASS OF 194.>
Number in Class: 45
Percent Donors: 24.4'^(
James R. Collett. M.D.. Morganlon. NC
John C. Foushce. M.D,. Santord. NC
William .V. Hiihharcl. .Ir. \l.l).. Hickory
Corners, MI
William F Hulson. Mi),. Noithhrook. II.
Alexander C. Mitchell. .M.D,. Onehioia. NY
Sarah T. Momnv. .M.D . PhD,. Raleigh. NC
S. Malone Parhani. M.D.. Henderson. NC
Frank R. Reynolds, M.D., Wilminj-ton. N(
James H. Shell. Jr.. M.D.. Baltimore. Ml)
Kenneth W. Wilkins, M.D., (ioldsboro, N(
Kenan B Williams. Ml),. Sanloid. NC
CLASS OF 1944
Number in Class: 27
Percent Donors: 40.7 '>
J \ incent Arey. M.D.. Concord. NC
Joseph W. Baggett. M.D.. Fayellevjilc. NC
Hilda II, Bailey. MO,. Salishury. NC
.1. Stuart (Jaul. Jr., M.D., ( harlotte, NC
J, Baylor Henninger. M.I),. Sl.ilesulle. NC
I laiKis P King, Sr. M.D.. Neu Beiii. NC
Is.i.ie \ Manlv. MD,. Raleigh. \C
( harles \. Speas Phillips. M.D.. Southern
Pines, Nt
J, Milchell .Soii.iu. Ji,. MD.t hapel Hill. \C
Charles W. Tillell. Ml).. Charlolle. N(
J Taylor Vernon, M.I).. Morganlon. .\(
CLASS OF 1 945
Number in Class: 24
Percent Donors: 41.7',
29
G. Walker Blair, Jr . M.D.. Burlington. NC
G. Robert Clutts, M.D., Greensboro. NC
A. Robert Cordell, M.D., Winston-Salem, NC
J. Hicks Corey. Jr.. M.D.. Chattanooga. TN
Courtney D. Egerton. Jr.. M.D.. Asheville. NC
Grafton C. Fanney. Jr.. M.D-. Bonita Springs. FL
Harold L. Godwin. .M.D.. Fayetteville, NC
Ben M. Gold. M.D.. Rocky Mount. NC
Kuhy T. Hart. Jr.. M.D,. Petersburg. VA
Edward R. Hipp. Jr., M.D.. Charlotte, NC
Weldon H. Jordan. M.D.. Fayetteville, NC
David Josephs. M.D.. Baltimore. MD
John H. Monroe, M.D., Winston-Salem, NC
John R. Pender 111. M.D.. Charlotte. NC
Roger A. Smith 111. M.D.. San Bemadino. C.A
Clitton F West. Jr.. M.D.. Chestenown. MD
CLASS OF 1446
Number in Class: 27
Percent Donors: 55.6 '/f
Ira \. .\brahamson, .In, M.D., Cincinnati. OH
Jules Anier. M.D.. Den\er. CO
Walter C. Barnes. Jr.. M.D., Texarkana. TX
Crowell T. Daniel. Jr.. M.D.. Fayetteville. NC
William W. Forrest, M.D., Greensboro, NC
Mary .Mice V. Fox, M.D., Mount Desert, ME
(;. Denman Hammond. M.D.. Pasadena, C\
Robert S. Lacke>, MD,. Charlolte. NC
William H. Sheely. M.D.. Alexandria. VA
H. Frank Starr, Jr., M.D.. Greensboro. NC
Da\id G. Stroup. M.D.. Savannah. GA
Arthur R. Summerlin. Jr., M.D.. Raleigh. NC
James T. Welbiini. M.D.. Lexington. NC
John E. Weyher. Jr.. M.D.. Wilmington. NC
Thomas E. Whitaker IL M.D.. Greenville. SC
CLASS OF 1^47
Number in Class: 15
Percent Donors: 13.3%
HaiTV G, Walker. M.D.. Statesville. NC
Sarah L. Waixen. M.D.. Chapel Hill. NC
CLASS OF 144.S
Number in Class: 26
Percent Donors: 34.6%
Robert R. Aycock. M.D.. Saint Helena. CA
Vema Y. Barefoot. M.D.. New Bern. NC
William S. Cheek. Sr.. M.D.. Spartanburg. SC
T\ndall P Hams. MD . Chapel Hill. NC
Edwin P. Hiatt. M.D.. Wilmington. OH
Louis T. Kermon. M.D.. Raleigh. NC
Julius A. MacKie. Jr. M.D.. Bryn Mawr. PA
Shirley L. Rivers. M.D., Tucson, AZ
Daniel T Young, M.D.. Chapel Hill. NC
CLASS OF 144'»
Number in Class: 37
Percent Donors: 32.4%
J. Dewey Dorsett. Jr.. M.D.. Charlotte. NC
Christopher C. Pordham III, M.D..
Chapel Hill. NC
John M Ganibill. MD,. Flkin. NC
K. Sidney (Jardncr. Jr.. M.D.. Fayetteville, NC
Odell C. Kinibrell. Jr.. M.D.. Raleigh. NC
Spinks H. Marsh. M.D.. Minneapolis. MN
Edward B. McKenzie. M.D.. Statesville. NC
Charles F Melchor. Jr.. M.D.. Myrtle Beach. SC
Edwin W. Monroe. M.D.. Green\ ille. NC
Robert B. Pennington. M.D,. Middletown. CT
Rose Pully. M.D.. Kinston. NC
30
Jonathan S. Swift. NLD.. Big Canoe. G.A
CLASS OF m.so
Number in Class: 41
Percent Donors: 70.7%
Gertrude A. Bales, M.D.. Rochester, NY
Frederick <), Bowman, Jr., M.D.. Chapel Hill, NC
W, Grimes B>crl>. Jr. .\1.D,. Hickory. NC
Jack O, Carson. MD.. Grifton. NC
Elwood B. Coley, M.D.. Lumberton. NC
John T. Dees. M.D., Bald Head Island, NC
Buel K. Grow. Jr.. M.D,. Belle Meade. NJ
William B. Hams. M.D,. Carlsbad. CA
Joel B. Huneycutt. M,D.. Lake Wylie. SC
Harold H, Jeter. Jr.. \LD,. Wilmington. NC
George Johnson, Jr., M.D., Chapel Hill, NC
Har\e\ VV, Johnston. M.D.. Charlotte. NC
William S, Joyner. NLD.. Durham. NC
John A. Kirkland, M.D.. W ilson. NC
Laurence B. Leinbach. M.D.. Winston-Salem. NC
Dan A. Martin. M.D.. Madisonville. KY
John L. McCain, M.D.. Wilson. NC
Glenn D. Moak. M.D.. Indianapolis, IN
James F, Morris. NLD,, Goldshoro. NC
James H, Pccdin. Jr.. M.D.. Burgaw. NC
J. Olin Perritt, Jr.. M.D., Wilmington. NC
John W, Sawyer. M.D.. Wilmington. NC
Eugene B. Sharpe. M.D,. Asheville. NC
Lewis S. Thorp. Jr.. M.D.. Rocky Mount. NC
John F. Trotter. NLD.. Atlanta. GA
Belk C. Troutman. M.D.. Grifton. NC
Charles R. Vernon. M.D., Wrightsville. NC
John L. Waiters. M.D.. Raleigh. NC
John R, Wilkinson. Jr.. MD.. Hickory. NC
CLASS OF I4.S1
Number in Cla.ss: 40
Percent Donors: 22.5%
Luther L. Anthony. Jr.. M.D., Gastonia. NC
John S. Barlow. M.D.. Concord. MA
W illiam B. BIythe II. M.D.. Chapel Hill. NC
Baxter 11, ByerK. NLD,. Tallahassee, FL
A. James Coppridge. NLD,. Durham. NC
Kari L. Lawing. M.D.. Lincolnton. NC
Murdoch R. McKeithen. M.D.. Laurinburg. NC
Luther W. Oehlbeck, Jr.. M.D.. Muse. FL
John K. Pearson. M.D., Apex. NC
CLASS OF 19.S2
Number in Class: 6
Percent Donors: 33.3%
Da\ id L. Collins. Jr.. NLD.. Concord. NC
Charies H. Powell. NLD.. Omiond Beach. FL
CLASS OF 1454
Number in Class: 34
Percent Donors: 47.1%
Leland S. .■Nverett. Jr.. M.D., High Point. NC
Paul H. Brigman. M.D.. Trinity. NC
A. Joseph Diab, M.D., Raleigh, NC
Malcolm Fleishman, M.D.. Fayetteville. NC
Charles B. Fulghum. Jr.. NID.. Atlanta. GA
J. Franklin Graves. NLD,. Mt, Pleasant. SC
Robert S. Jones. M.D.. Shelby. NC
James C. Parke. Jr. M.D.. Charlotte. NC
Cornelius T. Partrick. M.D.. Washington, NC
Ely J. Perry. Jr.. M.D., Kinston, NC
Allen Spencer, M.D.. Salisbury. NC
Nat H. Swann. Jr.. NLD,. Signal Nlountain. TN
H. Durwood Tvndall. MD,. Goldshoro. NC
William H. Weinel, Jr., M.D., W ilmington, NC
Virgil A. Wilson, M.D,. Winston-Saleni, NC
A. Donald Wolff. M.D., Clemmons, NC
CLASS OF 1955
Number in Class: 51
Percent Donors: 88.2%
Henry W. Abernethy. M.D.. Hickory, NC
Harvey Adams. .\LD.. .■Xshehoro. NC
Julian S. Albergotti. Jr., M.D.. Charlotte, NC
George W. Barnard. Sr., M.D., Gainesville. FL
Robert G. Brame, M.D.. Chariotte. NC
Ralph E. Brooks, Jr.. M.D.. High Point, NC
E. Ted Chandler. NLD,. Thomasville. NC
Walter E. Deyton. NLD . Dan\ ille. VA
Griggs C. Dick.son, M.D., Charlotte, NC
Presley Z. Dunn. Jr.. MD.. Greensboro. NC
Charles F. Eddinger. NLD.. Spencer. NC
John W. Foust, M.D., Charlotte, NC
John W, Gaines. Jr. NLD.. Newport. NC
J. Eugene (Jlenn. M.I).. Jacksonville. FL
Ira D. Godwin, M.D.. Fairfax. VA
Robert L. Golby. M.D. and Mary B. Golby. M.D..
Durham. NC
James W. Hayes III. M.D.. Burlington. NC
Charles L. Herring. M.D.. Kinston. NC
William D. Huffines. NLD.. Chapel Hill. NC
Vernon 1,. James. Jr.. M.D.. Fair Oaks Ranch. TX
Samuel G. Jenkins. Jr.. M.D.. Elizabeth City. SC
Robert C. Jordan. Jr.. M.D.. Sanford. NC
Samuel B. Joyner. NLD.. Greensboro. NC
James L, Lamm. NLD.. San Francisco. C.A
.\. Smith Lineberger. Jr.. M.D.. Wilmington. NC
William L. London \\. M.D., Durham, NC
Lloyd C, McCaskill. NLD,. Nlaxlon. NC
Clarence R. .McLain. Jr.. M.D.. Cincinnati, OH
Andrew C. Miller III, M.D., Gastonia, NC
J. Thaddeus Nionroe. Jr. NLD,. Chapel Hill, NC
Thomas P. Moore. M.D.. Jacksonville. NC
Frank C. Morrison. Jr., M.D., Canton, NC
(;. Irvin Richardson, M.D.. Reidsville. NC
Harold R, Roberts. MD,. Chapel Hill. NC
OIner K Roddey. Jr. NLD,. Chariotte. NC
C. W illiam Rogers. M.D.. Lebanon. TN
William C. RufTm. Jr.. M.D.. Boca (;rande.. FL
Palmer F Shelbume. M.D.. Greensboro. NC
Henry L. Stephenson. Jr.. M.D.. Washington, NC
Robert L. Summerlin. Jr.. M.D.. Dublin, NC
(;. Reginald Tucker, Jr.. M.D.. Emerald Isle, NC
W illiam J. Waddell. M.D.. Prospect. KV
W. Wallace W bite, M.D.. Cincinnati. OH
William H. While. Jr. NLD.. Gainesville, GA
CLASS OF 1456
Number in Class: 50
Percent Donors: 44.0%
Wade NL Brannan, NLD.. Port Arthur. TX
John W, Deyton. Jr.. M.D.. Jacksonville. NC
William E. Easterling, Jr., M.D., Chapel Hill, NC
John T. Evans, M.D., Chattanooga. TN
Charles W. Fowler III, M.D., Oriando. FL
Alexander F Goley. NLD,. Buriington. NC
Francis W. Green. NLD,. Albemarie. NC
John L, Ha/lehursi 111. M.D,. Asheville. NC
Otis NL Lowry. NLD,. Spnng Hope. NC
William W. McLendon. M.D.. Chapel Hill. NC
J, Doyle NIedders. NLD,. Raleigh. NC
Robert L. Murray, M.D.. Roanoke, VA
John W, Ormand. Jr. NLD,. Wilmington. NC
Chflon G, Pavne. NLD,. Reidsville. NC
Francis D. Pepper. Jr.. M.D.. \yinsroii-Salem. \C
William R. Purcell. M.D.. Laurinburg. NC
James F Richards. Jr.. M D . Orlando. FL
Thomas C. Suther. Jr.. .\I D.. Jackson Springs. NC
John W Vasse\. M D . Raleigh. NC
William B. Wood. M.D.. Chapel Hill. NC
Leonard S. Woodall. M.D,. PA.. Smithfield. NC
De\ve\ H. Yarley. M.D.. Durham. NC
CL.ASSOF \9^'
Number in Class: 50
Percent Donors: 44.0 '>
H. John Bradley. Jr.. .M.D.. Greensboro. NC
Jame^ R Clapp. M.D . Durham. NC
Robert S. Cline. M.D.. Sanford. NC
Luther H. Clontz. M.D.. Morganton. NC
William P. Cornell. .\1.D.. Phoeni\. .A.Z
George S. Edwards. Sr . M D . Raleigh. NC
John K. Farringion. M.D.. High Point. NC
J Grayson Hall. .\I.D.. Mount .Airy. NC
Bennett .A. Hayes. Jr.. M.D.. Fayetteville. NC
Jack B. Hobson. M.D.. Charlotte. NC
J. Paul Hurst. Jr. M.D . Rydal. P.A,
George L. Irvin III. M.D.. Coral Gables. FL
Richard \. Liles. Jr.. M.D.. Albemarle. NC
H. Mixwell .Momson. Jr. .M.D.. Southern Pines. NC
Har\ey A. Page. M.D.. Pikeville. K\
Raeford T. Pugh. M.D.. Washington. NC
James N. Slade. M.D.. Edenton. .NC
Nathaniel L. Sparrow. .M.D.. Raleigh. NC
James H. M. Thorp. M.D.. Rocky Mount. NC
Earl P. Welch. Jr.. M.D.. W inston-Salem. NC
Roben J. Whitlock. M D . Easton. MD
Dr. Benson R. and Mrs. Luclnda Holderness
W ilcox. Chapel Hill. NC
CLASS OF 1958
Number in Class: 50
Percent Donors: 38.0^f
James T Alley. .M.D.. .Macon. GA
Clarence \. Bailey. Jr. M.D.. Durham, NC
John I. Brooks. Jr.. M.D.. Tarboro. NC
.Maurice L. Canaday. M.D.. Lincolnton. NC
M. Paul Capp. M.D.. Tucson. AZ
David B. Crosland. M.D.. Mt. Pleasant. NC
James R Edwards. M D . Raleigh. NC
George E. Ennis. NLD.. Hickory. NC
Nancy P. Favvcett, M.D., Pembroke Pines. FL
Thomas VL Haizlip. .M.D.. Raleigh. NC
John S. Howie. M.D.. Raleigh. NC
Waller N. Long. Jr.. M.D.. Taylorsville. NC
Charles T. .Macy. .M.D . Lansdale. PA
John A. McGee. Jr . .M D . Charlotte. NC
Luther S. Nelson. M.D.. Amarillo. TX
T Lane Orniand. M.D.. Monroe. NC
J. Richard Patterson. .M.D.. Danville. \ A
Charles W. Stout. M.D.. Asheboro. NC
Paul .M. Weeks. M.D.. Chapel Hill. NC
CLASS OF 14.59
Number in Class: 48
Percent Donors: 41.7'^r
Doris B. Braxton. M.I).. Burlington. N(
Robert C. Brown. M.D.. ( hapel Hill. NC
Daniel Whilaker D.ivix. Ml). Wadesboro. NC
A. Eugene Douglas. Jr. Ml). Hald Hcid Island. NC
Otis N. Fisher. Jr. M.D.. (;reenshoro. NC
Cieorge W. (;entry. Jr. M.I).. Roxboro. NC
Joel S. Ciimduin. M.I).. Salisbury. NC
Robert 1.. (Jreen. Sr.. M.I).. Winslon-Sakin. N(
O. James Hart. Jr.. M.D.. Mocksville. NC
.■\. Tyson Jennette. .MD.. Wilson. NC
Morris A. Jones. Jr.. M.D.. Chapel Hill. NC
David L. Kelly. Jr.. M.D.. Winston-Salem. NC
Roben P Linker. M.D . Charleston. SC
Wilfred D. Little. Jr.. M.D., Ana Mana. FL
Edward L. Mitchell. M.D.. Prospect. KV
A. Sherman Morris. Jr.. M.D.. Ashevlllc. NC
Julian W. Sclig. Jr.. M.D.. Eli/ahcth City. NC
Shahane R. Taylor. Jr.. M.D.. Cireensboro. NC
Charles E. Trado. Jr.. M.D.. Hickory. NC
C. Carl Warren. Jr.. M.D.. Charlotte, NC
CLASS OF l%0
Number in Class: 63
Percent Donors: 60.3'!
\\ illiam B. Abernethy. Jr.. M.D., Gastonia, NC
Leo R Anderson. M.D.. Corona Del NLir. CA
Ralph L. Bentley. M.D.. Statesville. NC
James A. Campbell. M.D.. Charlotte. NC
John R. Curtis. M.D.. Athens. GA
John R. Dykers. Jr.. .M.D.. Siler City. NC
Charles R Eldndge. Jr.. M.D.. Houston. T.\
Gerald W, Femald. M.D,. Chapel Hill. NC
Charles E. Fitzgerald. Jr.. .M.D.. Maitland. FL
J. Thomas Fox, Jr.. M.D.. \allc Crucis, NC
David B. Garmise. M.D.. Blumon, SC
Roben H. Hackler 111. M.D.. Richmond. VA
James R. Harper. M.D.. Durham. NC
Ch.irles W, H.irns. M.D . Ch.irloite. NC
Falls L. Harris. M.D.. Cireenville. SC
G. Wyckliffe Hoffler. M.D.. Titusville. FL
L. Gordon Kirschner. M.D . Washington. DC
E. Carwile LeRoy. M.D.. Charleston. SC
James Ci. Mann. M.D.. C;olden. CO
James M. Marlowe. NLD.. High Point. NC
J. Gr.iy McAllister III. Ml). Chapel Hill. NC
K. Franklin McCain. M.D.. W inston-Salcm, NC
William N, Michal. Jr.. .MD,. High Point. NC
Cecil H. Neville. Jr. M.D.. Pinehurst. NC
Duncan S. Owen. Jr.. M.D.. Richmond. \ A
Robert B. Payne. M.D.. Mooresville. NC
Jerry M. Petty. M.D.. Charlotte. NC
Jean R Poinei, Ml) . Frederick. MD
Elizabeth \. Raft. NLD.. Durham. NC
Charles W, Robinson III. M.D.. San Antonio. T\
Hilliard F Seigler, M.D., Durham. NC
Robert F Sloop. Jr.. .M.D.. Wilson. NC
Elliott .Solomon. M.D.. Rye Brook. N^
G Thomas Strickland. Jr.. M.D.. Baltimore. MD
John C. Tayloe. M.D.. New Bern. NC
P Bun Vea/ey. .M.D.. Sarasota. FL
Kenneth Weaver. M.D.. Jonesborough. TN
John J. White. Jr.. M.D.. Winston-Salem. NC
CLASS OF 1461
Number in Class: 50
Percent Donors: 52.0'f
F. Stanley .\\ci>. Jr. .Ml),. Noilolk. \,\
H. David Bruton. M.D.. Carthage. NC
Cosmo A. Dita/io. M.D.. Ph.D.. C1iarlottes\ ille. \A
John W. Garden. NLD.. Lexington. KV
W illiam S. Gibson, Jr., M.D.. Riverside, PA
John C Graham, Jr, .M D,. Kitty Hawk. .NC
L Morgan Hale. M.D . Ch.ipel Hill. NC
Richard W Hudson. NLD , BaNb<iro, NC
William H. Koun. M.D.. Isle of Palms. SC
/ell A .McGec, M.D., Salt Lake City. IT
U. Stacy Miller. M.D.. Raleigh. NC
William W Mor.jan. Jr. M I) . Keno. W
.•\ Ray Newsome. M D . Winston-Salem. NC
C. Rex O'Briant. M.D.. Gilbert. AZ
William L Owens. M.D . Clinton, NC
Cecil H. Rand. Jr.. M.D,, Greenville. NC
Leon;ird E. Reaves 111. M.D., South Brunswick. NC
James H. Robinson. M.D.. Wilmington. NC
W. Ray Samuels. M.D.. Kiawah Island. SC
Edward .\. Sharpless. M.D. and Martha K.
Sharpless. M.D.. CJreensboro. NC
W Fenell Shutoid. Ji.. Ml).. Wilminglon. NC
Joshua Tayloe. M.D.. Washington. NC
Zebulon Wea\er 111. .M.D . Ashe\ille. NC
Donn A. Wells. M.D.. .Sea Ranch Lakes, FL
William H White. Jr. M.D.. Sanford. NC
CLASS OF 146:
Number in Class: 52
Percent Donors: 42.3'^f
Karl L Barkley. M D.. Greensboro. NC
William S. Bost. Jr., M.D.. Greenville. NC
Joseph H. Callicott, Jr, M.D., Lynchburg. V.A
Lawrence M. Cutchin. M.D.. Tarboro. NC
Jen-y J. Filer. MD,. Li\ingston. AL
Marion W, Grift'in. M D,. Asheboro. NC
Frederick D, Haninck 111. MD . Lynchburg. \A
H. CJerald Hartzog IH. .M.D.. Raleigh, NC
Ray M. Hayworlh. M.D.. Knoxville, TS
Charles M. Hicks. MD.. Wilmington, NC
J, Neuton .MacCoriiKick. Ml) . Raleigh. NC
John L. Monroe. M.D.. West End. NC
Kenny J. Morris, .M.D.. W ilmington, NC
William A. Nebel. NLD.. Chapel Hill. NC
W Gordon Peacock. NLD . San Francisco. C.\
Carl S. Phipps. M.D.. \Mnston-Salem, NC
Alton A. Reeder. M.D.. High Point. NC
Lambros C. Rigas. MD,. Rome, GA
D, Emerson Scarborough. Jr., NLD.. Raleigh. NC
Fuller A. Shuford, NLD., Asheville, NC
Miriam F Smith, M.D., Decatur. GA
Roy V. Vamer, M.D.. Houston, TX
CLASS OF 146.^
Number in Class: 52
Percent Donors: 40.4'(
W illiam P Algary. M.D.. C;reen\ille, SC
Neil C. Bender. M.D.. New Bern. NC
W P.iul Riggers. M D . Clupel Hill. NC
I. Kelman Cohen. NLD.. Richmond, \.\
John W, Dallon. Jr.. NLD.. Santa Nlonica. CA
Da\e NL Da\is. M D . Atlanta. GA
William B, Deal. NLD,. Bmmngham. AL
J. Nlichael Gallagher. NLD.. Seattle. \\A
Ira M. Hardy II. M.D.. Greenville. NC'
William () Jolly 111. NLD.. Albemarle. NC
Charles I. Loftin HI, M.D., Roanoke. VA
J. M. McLean, M.D., Peoria, 11.
Eugene W. Pate. Jr.. M.D., Kinsion. NC
Charles J. Sawyer 111. Ml),. Ahoskie. NC
Samuel E, Scott. NLD.. Burlington. NC
Richard W. Shermer. M.D.. Chapel Hill. NC
DaMd W. Sillmon. NLD.. Greensboro, NC^
Jen-y A. Smith, NLD., NIemphis. TN
W. Landis Voigl, M.D , Edenton, NC
Ro\ A Weaker. Nil). Fa>etle\ ille, NC
DaMd R Williams. Si . M I),. lhomas\ille. NC
CLASS OF 1464
Number in Class: 54
Percent Donors: 25,'»'<
J. Nichols Beard. M,l)„ ( harlolle. N(
Harry L. Broome, M.D., Alpharetta, GA
John R. Ctlla. M.D.. Raleigh. NC
Roy L, Curr). Jr.. M.D., .San Francisco. CA
James F. Earnhardt. M.D.. Winston-Salem. NC
G. Patrick Henderson. Jr.. M.D.. Southern Pines. NC
E. Citniiack Holmes. Jr.. M.D.. Pacific Palisades. CA
D. Charles Hunsinger, M.D., Kin.ston, NC
E, Woodnnv Hum. Jr.. WD.. La Jolla. CA
W. Kirhy Kilpatrick. .|r, M.I).. Pinehurst, NC
Noel B. McDevitt. M.I).. .Southern Pines, NC
Artus M. Moser, .Jr., M.I)., .Swannannoa, NC
Marshall K. Redding, .M.I)., Long Beach, CA
James W. Rose. Jr.. .M.D.. Madison. Wl
CLASS OF 1 465
Nuniher in Class: 57
Percent Donors: 42.1%
G. William Bates. M.D.. Brentwood. TN
Hal F Collier. M.D.. Flowery Branch. GA
Takey Crist, M.D., Jacksonville, NC
Robert \. Fulk. Jr.. Ml).. Wilnimgton. NC
Kdgar (;. (Jallagher, Jr.. M.I).. Jacksonville, NC
Mar\iii R. Cloldsiem. M.I).. Scollsdalc. .\Z
Rohert I,. (Jrubh, Jr., .M.D., (Jlendale, MO
Joe W, Hardison. M.D., Fayetteville. NC
Alexander C. Hattaway 111. M.D., Raleigh. NC
Das id C. Hcleltlnger. M.D.. Tuscaloosa. AL
Howard Holderness. Jr., M.D.. Greensboro. NC
.loe P Hurt. M.D., Ph.D., .Sylva, NC
Bcrn.ird R J.ick. .Ml).. A/le. T,\
Rohert I. Kindley, M.D., Mary Esther, FL
RiclKird H. Lassiier. M.D.. Chapel Hill. NC
(Jordon B. LeCJrand, M.D., Raleigh, NC
Sue E. Massey. M.D.. Scotts Valley. CA
William D. McLesler. M.D.. Ph.D.. Fayette\ ille. NC
Donald D. McNeill. Jr.. M.D.. Lenoir. NC
l.leuellyn Phillips II, M.D., Renton. WA
Thomas L. Presson. M.D.. Greensboro. NC
William F. Sayers, M.D., Winston-Salem, NC
Evin H, Sides 111. M.D.. Raleigh. NC
Wilhs H, Williams. Ml).. Atlanta. GA
CLASS Ol- h)(i(i
Number in Class: 63
Percent Donors: 49.2%
J. Curtis Abell. M.D., .Statesville. NC
Robert P Bamnger. M.D.. Gastonia. NC
Rohert H. Bilhro. M.D.. Raleigh, NC
Tmiotin i:. C'loningcr. Ml),. Charlotte. NC
(Jeorge W. t (>\, M.D.. Atlanta, GA
William M. t rutchfleld. M.D.. Elizabeth City, NC
Philip C. Deaton. M.D.. Greensboro. NC
Kdgar C. (Jarrabrant II. M.D.. Raleigh, NC
Robert C. (;ibson III, M.D.. Portland, OR
Carol H. Hacketl. Ml),. Mercer Island. WA
Law rence I). Henry, M.I).. Jefferson City. MO
Howard T Hinshau. MI).. Ch.irlotte. NC
N, Neil Howell. Ml),. Charlotte. NC
William C. Hubbard, M.D.. Raleigh, NC
Hugh A. McAllister. Jr.. M.I).. Houston. T\
Kdgar M. McCiec. M.D.. Lexington, KV
Duncan Morton. Jr.. M.D,. Charlotte. NC
Hugh (;. Murray, Jr., M.D., Atlanta, GA
R. Kenneth Pons. M.D., Medtord, OR
James A. Pressly. M.D.. Charlotte. NC
Surry R Roberts. M.D.. Raleigh, NC
Charles K Scott, M,D,, Haw River, NC
Robert K. Sevier, M.D., tireensboro, NC
J. Lewis Sigmon, Jr., M.D., Davidson, NC
H Lee Smyre, M.D., Greer. SC
^2
E. Walker Stevens. Jr.. M,D.. Greensboro. NC
W. Beverly Tucker III. M.D.. Henderson. NC
W. Hunter Vaughan, M.D., Steubenville, OH
James H. Whicker. M.D.. Raleigh. NC
John A. Young, M.D., Charlotte, NC
James A. \ount. M.D.. Charlotte. NC
CLASS OF 1967
Number in Class: 67
Percent Donors: 46.3%
F Walton A\ery. M.D.. Chapel Hill. NC
Rudy W. Barker. M.D., Durham. NC
Gerald W, Bl.ikc. .M.D,. Raleigh. NC
Thomas \\. Bundy. M.D.. Chambersburg. P\
Joseph M. Cr.uer. M.D.. Atlanta. GA
Vartan .A. Davidian, Jr., M.D., Raleigh, NC
Da\id .-X. Evans. M.D.. Monroe, NC
R. Donald Garrison, M.D., Jacksonville, FL
Harvey J. Hamrick, M.D.. Chapel Hill. NC
K. Franklin Hart. Jr., M.D., Morganton. NC
L. Fuller lIone>cutl. Jr.. .\1,D . Raleigh. NC
James I). Hundley, M.D., Wilmington, NC
Scott (;. Kleiman. M.D.. Marietta. GA
Frank W. Leak. Sr.. M.D.. Clinton. NC
Hugh T. LetJer. Jr.. M.D. and Constance Farthing
Letler. Ph.D. Fori Worth. TX
Robert W. Madry. Jr., M.D., Corpus Christi,
TX
W. Jason McDaniel. Jr.. .M.D., Raleigh, NC
Joseph T. Mcl.anih. Ml),. Goldsboro. NC
Donald H. McQueen III. M.D.. Rock Hill. SC
Rudolph I. Mint/. Jr.. .M.D.. Kinston, NC
Harold B. Owens. M.D.. Danville. VA
II Richard Parker, Jr.. .M.D.. Greensboro. NC
(ierald Pelletier. Jr.. M.D.. New Bern, NC
Albert L. Roper II. M.D.. Norfolk, VA
Douglas M. Russell. M.D.. Goldsboro, NC
Walter R. Sahiston. M.D.. Kinston. NC
James H. Spruill, M.D,. Jackson. TN
Henry I'. Thomason. Jr.. M.D.. (Jastonia, NC
Benjamin K. Ward. Jr.. M.D.. Florence, SC
Barry M. Welborne. M.D.. Charlotte. NC
CLASS OF l%X
Number in Class: 62
Percent Donors: 43.5%
Joseph P. Archie, ,Ir.. M.D.. Raleigh, NC
George W. Bensch. M.I),. Stockton. CA
Lucius Blanchard. Jr.. M.D.. Las \egas, N\
Edward W, DaMdi.m, .M.D . Ch.ipel Hill. NC
Alan Davidson HI, M.D., (Jreensboro, NC
Ten-\ D. Golden. M.D.. Atlanta. GA
Theodora L. Gongaware. M.D.. Savannah. GA
Joseph \V. Griffin, Jr.. M.D.. Augusta. GA
W, F Hancock. Jr.. M.D.. Burlington. NC
Hoke F Henderson. Jr.. M.D.. Columbia, SC
John L. Kirkland 111. M.D.. Houston, TX
Edward W. Kouri, M.D.. Charlotte. NC
Jerold E. Lancourt. M.D.. Dallas. TX
Paliick T. Malone. M.D.. Rosuell. GA
Robert G. Martin, M.D., Southern Pines. NC
Rulhertoid B. Polhill. Jr.. M.D.. Birmingham. AL
David M. Rubin. M.D.. Greensboro. NC
Carole \\. Samuelson. M.D.. Birmingham. ,\L
E. Franklin Shavender. M.D.. Durham. NC
Robert B. Sheann. M.D.. Rockville, MD
Valerie L, Slallings, M.D.. Norfolk. VA
George S. Stretcher. M.D.. Spartanburg. SC
William S. Teachey. M.D.. Virginia Beach. VA
Robert C. Vanderben^. Jr.. M.D.. Raleiah, NC
Jerry C. Woodard, M.D., Wilson, NC
Richard H. Wra\ III, M.D., Morehead City. NC
Stephen W. ^oung. M.D., Austin, TX
CLASS OF 1969
Number in Class: 64
Percent Donors: 37.5%
P. Kugene Brown, M.D., Hickory, NC
J. Hugh Bryan, M.D., Fayetteville, NC
W. Woodrim Burns. Jr.. M.D.. Chapel Hill. NC
Don C. Chaplin, M.D., Burlington, NC
R. Samuel Crom.irtie 111. M.D.. Omiand Beach, FL
Hugh J. Grant. Jr.. M.D., Raleigh. NC
G Patrick Guiteras. .M.D.. Chapel Hill, NC
Edward W. Haseldcn. Jr., M.D., Columbia, SC
J Thomas John, Jr.. M.D.. Nashxille. TN
Dr. and Mrs. W illiam R. Jordan, Fayetteville. NC
Richaid A. Keever. M.D.. High Point. NC
Edward H. Lesesne. Jr., M.D., Canton, NC
C. Clement Lucas. Jr.. M.D.. Larchmont. N^l'
Henry J. MacDonald. Jr.. M.D.. New Bern. NC
R. James MacNaughton, Jr., M.D., (ireenville, SC
David W, Peaisall. Jr.. M.D.. Greenville. NC
James S. Powers. M.D.. Bethesda. MD
Joseph D. Russell, M.D.. Wilson, NC
David S. Sheps. M.D.. Gainesville. FL
James W. Snyder. M.I).. W ilmington. NC
Karen C. .Sorrels. M.D,. Midlothian. \ A
Franklin T Teu, Ml),. Chapel Hill. NC
John t . Triplett. M.D.. M.P.H.. Bethesda. MD
Nelson B. Watts. M.D.. Atlanta, GA
CLASS OF 1970
Number in Cla.ss: 70
Percent Donors: 61.4%
H. Chlford Baggett, Jr., M.D., Rocky Mount, NC
Jerry C. Bernstein, M.D., Raleigh, NC
Robert G. Blair. Jr. M.D. and Pauline M. Blair.
MI). New Bern. NC
William J. Busby. M.D.. Thomasville. NC
William K. Byrd. M.D.. Roanoke Rapids, NC
Harold H. Cameron. M.D.. New Bern. NC
Daniel L. Crocker. Jr., M.D.. Rocky Mount, NC
Ch.irles E. Crumley. M.D.. Lincolnton. NC
H. Shelton Karp HI, M.D. and Joanne Karp.
Ph.D., Chapel Hill, NC
Mary H. Edwards. M.D. and David J. Edwards.
PhD,. Pittsburgh. PA
Richard M. Freeman. M.D.. Opelika. AL
James O. (ioodwin. M.D,. Henderson. NC
John F. Hanna. M.D.. Sarasota. FL
Joseph M. Harmon. M.D.. Mount Pleasant, SC
John K Ilartness, Jr.. M.D.. Monroe. NC
W. Borden Hooks. Jr., M.D., Mount Airy, NC
Donald 1). Howe. M.D,. Gastoni.i. NC
Dr. and Mrs. Mark G. Janis. Seal Beach, CA
James J Jenkins. M.D.. Saint Louis. MO
V. Bryan Koon. Jr.. M.D.. Durham. NC
Frederick (i. Kroncke. Jr., M.D., Rocky
Mount, NC
John R. Leonard 111. .M.D.. Greenville. NC
James D. Melton. M.D.. Morganton. NC
Michael A. Moore. M.D., Danville, VA
Edward A. Nortleet. M.D.. Chapel Hill, NC
L. Christine Oliver, M.D., Brookline, MA
Hoke Pollock. M.D.. Wilmington. NC
R Kirhy Primm, .M.D . Wenatchee. WA
David A. Rendleman HI, M.D., Raleigh. NC
Thomas A. Roberts, Jr„ M.D., Charlotte, NC
Subir Rov, M,D., Pasadena, CA
A. Stevens Rubin. Jr.. M D . Chatsworth. C.A
James B. Sloan, M.D., Wilmington, NC
Kenneth W. Sniithson. .\!.D.. Inins;. T\
Jame>. D. Smithwick. M-D.. LaurMiburg. NC
Charle-s E. Thompson, .M.D., New Rochelle, W
T. Reed I nderhill. M.I).. NeH Bern. NC
Ross L. \aughan. M.I).. Raleigh. NC
E. Lance Walker. M.I).. Littklon. fO
William ,|. Weatherlj. M.I)., (ireenshoro. NC
H. Grev Wintield 111. .\1.D.. llickon. NC
CLASS OF 1471
Number in Class: 73
Percent Donors: 24.7 'r
Robert A. Bashford, M.D.. Chapel Hill. NC
J,imes S. Co\e 111. .\1.D . Ralcii:h. NC
James S. Fulghum III. M.I), and Mar) Susan
Fulghum. .M.I)., Raleigh. NC
Joe E Gadd>. Jr . M.D.. W inston-Saleni. NC
Daniel P. Greenfield. M.D.. Short HilK. NJ
Michael R. Knowles, M.D.. Chapel Hill. NC
Kathnn R. Ku\kendal. Cineinnati. OH
Richard A. Nelson. M.D.. Cordo\a. TN
Frederick S. Neuer, .M.D., Emporia, KS
William B. Piltman, M.D.. Rock> Mount. NC
R. R.indolph P.mell. .\1.D.. Ho\ Point. \VI
Charles H. Richman. M.D.. Saratoga Springs. N"^
Virgil O Roberson 111. M.D.. High Point. NC
J. Allison Shivers. M.D., Asheville, NC
Sara H Sin.il. Ml). W insion-Saleni. NC
John P. Surratt. M.l).. Clinton, NC
George C. \enters, M.D., Raleigh, NC
David K Wagoner. M D.. Charlotte. NC
CLASS OF 14";
Number in Class: 70
Percent Donors: 37.1 "^^
Henrv H Atkins 11. .\1.D.. Hampden. ME
Robert L. Barnes 111. M.D.. Knoxville. TN
Myron H Brand. M.D.. .Madison. CT
Peter R. Bream, M.D., Jacksonville, FL
L. Franklin Cashuell. Jr.. M.D.. Greensboro. NC
Randolph B. Cooke. M,D.. Owego. N't
Cecil M. Famngton. Jr.. M.D.. Salisburv. NC
Karen W. Green. M.D . Holden. .\IA
Alger \'. Hamrick 111. M D . Raleigh. NC
L. Clayton Harrell III. M.D.. Charlotte, NC
Hubert B. Hasuood 111 .Ml) . Raleigh. NC
F. Christian Heaton. M.l).. Raleigh, NC
Larrv A High. Jr . .\1 L).. Rockv Mount. NC
Wilham B Horn. .M.D . Boone. NC
John S. Hughes, M.D.. .New Haven. CT
Thomas G. Irons. .M.D.. Greenville. NC
Joseph A. Jackson. M.D.. Pilot .Mountain. NC
Howard S. Kroop. M.I).. Woodbury. NJ
William \. Long. Ml). Ne«lnn. N(
John R. Lurain III, M.D.. Oak Park, IL
John T .Manning. Jr.. M.D,. Houston. TX
John R. Partridge. M.D.. .Midlothian. VA
lames S. Reed, M.D., (;ig Harbor. WA
I I ledenck Wolfe. M D.. Knovsillc. IN
J Kieh.ird Young. .Ml).. Sherborn. MA
CLASS OL 147 <
Number in Class: 81
Percent Donors: 35.8 'i
Frederic F. Bahnson 111. M.D.. Brevard. NC
Ci RutTin Benton 111. .VI. D.. Brevard. NC
Stephen A Bernard. .M.D.. Chapel Hill. NC
Stephen B. Billick. .M.D.. New York. NY
Jesse A. Blackman. M.D.. PA.. Fremont, NC
Thomas B. Cannon. M.D.. Winston-Salem. NC
Nad\ M Gates 111. .\I D . Chapel Hill. NC
Franklin S. Clark III. M.D.. Kayetteville. NC
LKnd K. Conistoek. M.D.. Snow Camp. NC
Frank E. Davis HI. M.D.. Roanoke Rapids. NC
John E. Estes. Jr.. M.D.. Rocky Mount, NC
L, Rultni Franklin. Jr.. M.D.. Raleigh. NC
J. Blake Goslen 111. M.D., Charlotte. NC
David A. (Jrimes. .M.D.. Chapel Hill, NC
J Michael Harper. M.D.. Charlotte. NC
F Daniel Jackson. M.D.. Cumberland. MD
E. Earl Jenkins. Jr.. M.D.. Rock Hill. SC
J. t harles Jennette. M.l).. I hapel Hill. NC
Dennis R Johnson. .\1 D . ^ork. PA
Colin D Jones. .M D . Ahoskie. NC
James L. Maynard, M.D., Rock Hill, SC
Dale A. Newton. M.D.. Green\ille. NC
David R. Patterson, M.D., Greensboro, NC
W. McLean Reavis. Jr.. M.D.. Lakeland. FL
Da\ id E. Sharp. M.D.. Ph.D.. Bear Creek. PA
S. Wa>ne Smith. M.D.. Raleigh. NC
George H, Lnderwood. Jr.. M.D., Honolulu. HI
Robert R. Walthtr, M.D.. New York, NY
William H, Whisnant. M D.. Bristol. TN
CLASS OF 1474
Number in Class: 97
Percent Donors: 33.0'>
Robert M. Alsup. M.D., Winston-Salem, NC
Thomas W. Bouldin. M.D.. Chapel Hill. NC
W. Gnft'lth Bowen. M.D., St. Louis. MO
Douglas C. Brewer. M.D.. Elm City. NC
Donald C. Brown. M.D.. Can. NC
David R. Clemmons, M,D., Chapel Hill. NC
Thomas H. Dukes 111. M D.. Charleston. SC
Donna E. Fnck. .M.D.. Chapel Hill. NC
Stephen S. Hawkins. M.D.. Hixson. TN
C. Norman Hurwii/. M.D.. Fairfield. Oil
Joseph M. Jenkins, M.D., Fayetteville, NC
Stephanie L. Kodack, .M.D., .Austin, TX
John A. Lang 111. M.D.. Raleigh. NC
Clarence E, Lloyd. Jr.. MD.. Greensboro. NC
Sheppard A. McKenzie III, M.D., Raleigh. NC
Cl\de Nolan. Jr.. M D.. Greensboro. NC
II. Clill(m Patterson III. M.l).. Raleigh. NC
Harold C . Pollard III. M.l).. Winston-Salem. NC
C. Eredric Reid, M.D.. W inston-Salem. Nl'
Su/anne V. Sauter. .VI. D.. Chapel Hill. NC
Charles W. Smith. Jr.. M.D.. Little Rock. \R
Roger L. Snow. VI. D.. Boston. VIA
Da\id E Tart. VI D. Hickorv. NC
David T. Tayloe, Jr., M.D., Goldsboro, NC
John W. Thornton 111. VLD.. Augusta. GA
Larry E. WaiTcn. M.D.. Chapel Hill. NC
Charles H. Weiss. M.D.. Newton. MA
Kenneth H. Wilson. VLD.. Chapel Hill. NC
William G. Wilson. VLD . t harloiiesvillc. VA
Heishel L. Wi\. Jr.. .VLD.. VI. nice. IL
Charles I), ^bder. VLD.. FairMcw. NC
I). Bryan Young. M.D.. Shelby. NC
CLASS OF I47.S
Number in Class: Mlfi
IVrccnl Donors: Ai).<,' ,
I., .lackson Allison. .|r.. VI. I)., last Syracuse. N^
Bruce A. Bellow. VI 1). Vlsslic. ( I
William J. Blacklev. VI. D.. KIkin, N(
Julian CBunllev 111. VI I) . Rock\ Vloum. N(
Julian T Branllev. Ji . VI I) . Vienna. \ A
Patrick G. Bray. M.D.. Shaker Heights. OH
Samuel L. Bridgers II. M.D., Woodhridge, CT
E. Drew Bridges. VLD.. Wake Forest. NC
Cvril S. Dodge. M.D.. Vancouver. WA
Benjamin Douglas. VLD.. Dillsboro. NC
William H. Edw.iids. VI D and Susan T
Edwards, M.D-. Norwich. \T
Clarence E, Foglem.ui 111. M I).
Colorado Springs. CO
Richard F. Fox. VI. I).. Cireensboro. NC
Donald C;. Ciregg, M.D.. CJreenville, SC
Eric H. Hels.ibeck. VLD . Asheboro. NC
Ernest E Krug III. VI. I).. Rochester. MI
C harles P. I.anglev III. VI. 1).. Shelby, NC
David S. I.ennon. VI. I).. C harlotte, NC
Howard A. VIcVlahan. VI. I).. Vlarietia, (iA
Frank 11. VIoiet/. VLD.. .\shc\illc. NC
Wade H VIoser. Jr.. VLD.. Raleigh. NC
Dan A. Myers, M.D.. Kinston, NC
]\. Ronald .\eal, M.D., Greensboro, SC
Henry N Nelson 111. VLD.. Indialantic. FL
Lanning R, Newell. VLD.. Raleigh. NC
Vlaishall ILOdoin. M.I). Boone. NC
Stephen L. Okiye, M.D., Saint Thomas, \ I
Henrv E. Parfiti. Jr.. VI. D.. Fayetteville. NC
H. Worth Parker. M.D., Norwich, VT
Jerry E. Patterson. M.D., Chapel Hill. NC
James E. Peacock. Jr.. VLD.. Winston-Saleni. NC
Claudia A. Peters. VLD.. Kingston. ON
Joseph B Philips 111. VI I),. Birmingham. AL
Hoke D. Pollock, Vl.D., W ilmington, NC
James L. Price 111. M.D., Wilmington. NC
Joseph R. Pringle. Jr.. M.D., Burlington. NC
W. Paul Sawyer. M.D.. Tallahassee. FL
Michael A. Stang. M.D.. Pikesv ille, MD
Kenneth K. Steinweg. VLD . Greenville. NC
Carol B. Teutsch. VLD.. Gwvnedd \allev. PA
James W, Winslow. VLD.. Tarboro. NC
Kenneth II. W inter. VI. I)., (ireenshoro. NC
CLASS OF 147(1
Number in Class: 12(1
Percent Donors: 3(1.0 '-f
Bienda L Adams Hudson. VLD.. VIooie. SC
Warwick Aiken III. VLD. and Janet Cyhiynski
Aiken. VLD.. Gastoma. NC
Paul D. Barry. M.D.. CJreensboro, NC
Vlartin F Beals. Jr.. VI D . Bluefield. \ A
Jean C. Bolan. M.D.. Washington. DC
AlevisC BoutenetL VI. 1).. Litchfield. CI
Rich.ird A Bowerman. VLD . Ann Arbor. VII
Barbara J. Campbell. Vl.D.. Somerset. PA
Vlariorie B. Can. Vl.D.. Raleigh. NC
F^dward I.. Cattau, Jr.. Vl.D.. (Jernianlown. IN
William II. (iamble. Vl.D.. (ireensboro, NC
( harles II. Hicks, Vl.D.. W ilmington. NC
J. Lee llollci. Vl.l). leiiiplc. I .\
Robert H. Hulchins. M.D.. Wilmington. NC
Walker A. Long. .VLD.. Ch.ipel Hill. NC
Ross I) Lvnch. VI I) . ColiiinhLi, S( '
VlcKav VkKmnon. VI I) . Kciiiluoiih. II.
Michael \: Vlillei. VLD. Iiaiiklm. IN
B Douglas VIorton III. VI 1) . Vlacon. GA
Robert S. VIoskalik. VI 1) . Coldwatei. Vll
E. Paul Nance. Jr., M.D.. Nashville. TN
I. Andrew Nassel. Jr. VI I) . Danville. PA
David B. Neeland. Vl.D.. VIontgomery. AL
ll.irokl A Nichols. VLD . Giecnsboro. NC
Kathleen (iallagberOxner. M.l).. (ireenv ille. SC
Sheldon VI, Rclchin. VI I). Richmoiul, \ \
Tamara L. Sanderson, M.D., Lexington, KV
Robert S. Shapiro. M.D.. Athens. GA
David F. Silver. M.D.. Charlottesville. VA
Robert J. Tallaksen. .M.D., Morgantown, WV
R. Henry Temple. Jr.. M.D,. Wilmington. NC
F. Ray Thigpen, M.D., Whiteville, NC
Mark E. Williams. M.D.. Charlottesville. VA
Riehard L. Wing. M.D.. Charlotte. NC
Sabra A. VVoodard, M.D.. Raleigh, NC
CLASS OF 1977
Number in Class: 119
Percent Donors: 24.4 9}
.Michael L, Ban-inger. M.D.. Shelby. NC
.lohii R. Black. M.D.. Zionsville. IN
Clinton A. Bnlev. Jr. M.D.. Wnghtsvillc Beach. NC
Francis S. Collins, M.D., Ph.D.. Rockville, MD
Joseph E. Craft. M.D.. Guilford. CT
Allen J. Daugird. M.D.. Chapel Hill. NC
Meyer E. Dworsky, M.D., Huntsville, .\L
Wayne D. Fogle. M.D.. Knowille. TN
Peter C. Gruenberg. M.D.. .^Itamonte Springs. FL
Charles H. Hoover. III. M.D.. Monroe, NC
William L. Isley. M.D.. Kansas City. MO
L. Lyndon Key. Jr.. M.D. and Janice D. Key.
M,D.. Hollywood. SC
Judith M, Kramer. M.D.. Chapel Hill. NC
Frederick 11 Mahry. Jr. MD.. Lanrinhurg. NC
•Stephen Ray .Mitchell, M.D., Alexandria, VA
Warren H. Moore, M.D., Sugar Land, TX
H. Grady Morgan. Jr.. M.D.. Wilmington. NC
Pamela A. Nel.son. M.D.. Raleigh. NC
Scott H. Norwood. M.D.. Tyler. TX
Louis M. Perlniutt, M.D., Chapel Hill, NC
Michael L. Pool. M.D.. Knowille. TN
Duncan S. Postma. M.D.. Tallahassee. FL
Catherine M. Radovich. M.D.. Gallup. NM
Samuel T Selden. M.D.. Chesapeake. VA
Howard J. Stang. M.D.. Stillwater. MN
.lohn H. Stanley, Jr., M.D., Wilmington, NC
Michael M. Ward. M.D.. Wilmington. NC
Richard H, Wcislci. MD,. Raleigh. NC
CLASS OF l')7S
Number in Cla.ss: 129
Percent Donors: 25.6'7f
T Rupert Ainsley. Jr.. M.D,. Sanford, NC
Michael C. Alston. M.D,. Murtreesboro. NC
James J, Bedrick. M.D.. Charlotte. NC
John D. Benson, M.D., Cary, NC
Jean W. Carter. M.D.. Raleigh. NC
Brian J. Cohen. M.D.. Sudbury. MA
Cvnlhia D Conrad. M D,. PhD,. Branford. CT
Paul W. Coughlin, M.D., High Point, NC
Betty J, Crosby. M.D,. Charlotte. NC
Allison J. Dudley. M.D.. Charlotte. NC
Martha L. Elks. M.D.. Atlanta. GA
Seth V. Hetherington. M.D.. Chapel Hill. NC
Michael D. Holland. M.D.. Rocky Mount. NC
Cynthia R. Howard. M.D.. Baltimore. MD
Dorothy M. Linster. M.D.. Raleigh. NC
Wade L. Lowry. M.D,. Colleyv ille. TX
Jeftiey A. Margolis. MD.. Tappahannock. VA
John T. McElvecn, Jr., .M.D.. Raleigh. NC
W. Ronald MofFitt. M.D.. Hendersonville. NC
Mark D. Monson. M.D.. Spartanburg. SC
Donna L. Prather. M.D.. Carrboro, NC
John V Pruitt 111. M.D.. Boston. MA
Peter A. Schlesinger. M.D,. St. Paul. MN
Stuart C, Segerman. M.D.. .Atlanta. GA
Susan T. Snider, M.D., Burnsville, NC
William D. Snider, .M.D., Chapel Hill, NC
Donna S. Sperber. M.D.. St. Petersburg. FL
Alan D. Stiles. M.D.. Chapel Hill. NC
Gregory H. Tuttle. M.D.. Mebane. NC
Wilham A. Walker. .M.D.. Charlotte. NC
J. Byron Walthall. Jr.. M.D. and Nancy L.
Teafl. .M.D.. Charlotte. NC
Richard C. Worf. M.D.. Winston-Salem. NC
CLASS OF 1979
Number in Class: 128
Percent Donors: 28.1%
Andrew H, Balder. .M.D.. Longmeadow. MA
Gail .M. Capel. .M.D.. Schenectady. NY
D. Franklin Craig. M.D.. Burnsville. NC
Waller E. Daniel. Jr.. M.D.. Raleigh. NC
Douglas M. Delong. M.D.. Ladysmith. WT
Allen R. Edwards. M.D. and Palncia K. Hill.
M.D.. Statesville. NC
Ellen B. Fitzgerald. M.D.. Lexington. KY
Sharon M, Foster. M.D.. Raleigh. NC
Thomas R. Hinson. Jr.. M.D.. Clemmons. NC
Kent M. Kalina. M.D.. Charlotte. NC
Anne T. Keifer. M.D. and John C. Keifer. M.D..
Chapel Hill, NC
John M. Lafferty. M.D.. Valdese. NC
Charles E. Lownes. M.D.. Greensboro. NC
Julia E, McMuiTay. M.D,. Madison. Wl
Darlyne Menscer, .M.D., Charlotte. NC
Harold P Overcash. MD.. Raleigh. NC
Christian E. Paletta. M.D., St. Louis. MO
Lawrence H. Pearson. M.D., Shelby. NC
James G. Peden, Jr.. M.D.. Greenville. NC
Alan M. Ranch. M.D.. Santa Barbara. CA
Charles N. Reed. M.D.. Hickory. NC
J, Mark Rowles. M.D.. .Atlanta. GA
James L. Sanderford. Jr., M.D., Lewisville, NC
David M. Siegei. M.D.. Rochester. NY
William L. Stewart. M.D.. Southern Pines. NC
Frances R. Thomas. M.D.. Chicago. IL
Paul A. Vadnais. MD.. Charlotte. NC
Lynn E. Wesson. M.D,. Raleigh. NC
Mack W. White III. M.D., Charlotte, NC
C, Phillip Whitworth. M.D.. Forest City. NC
Lan-y T Williams. M.D,. Hickory. NC
Leonard S. Wojnowich. M.D.. Savannah. GA
O. Ban-y Wynn. M.D. and Michelle H Wvnn.
M.D.. Charlotte. NC
CLASS OF 1980
Number in Class: 145
Percent Donors: 36'7<-
Edward H. Bertram 111. M.D,. Charlottesville. VA
Roger D, Billica. M.D.. Houston. TX
Marcus E. Carr. Jr.. M.D.. Midlothian. VA
Wilbur B. Carter. Jr.. M.D.. Chapel Hill, NC
Lauren E. Cosgrove. M.D., Potomac. MD
Phillip K. Dorton. M.D.. Thomasville. NC
Patricia T. Edkins. M.D.. Chapel Hill. NC
W. Wells Edmundson. M.D.. Raleigh. NC
Walter E. Egerton 111. M.D.. Aberdeen Proving
Grounds. MD
C. O'Neil Ellis, M.D.. Matthews, NC
Barry J. Freeman. M.D.. Los Angeles, CA
Fredenck U. Goss. M.D.. Salisbury. NC
John C. Gudger. M.D.. Swansboro. NC
Sandra K. Haigler. M.D.. Lexington. KY
Catherine J, Hants. M.D.. Wilmington. DE
Call L, Havnes. Jr. M.D,. Kinston. NC
Mark A. Helvie. M.D,. Ann Arbor. MI
J. Patrick Holland. .M.D., Winston-Salem, NC
Kenneth E. Hollingsworth. M.D.. OIney. MD
Philip R. Johnson, Jr.. M.D.. New Albany. OH
Edward C. Jones. M.D.. Clemmons, NC
Konrad C. Kaltenbom. M.D.. Anchorage. AK
Daniel M. Lewis. M.D.. Charlotte. NC
Thomas H. Lineberger. M.D.. Pinehurst. NC
Jimmy Locklear. M.D.. Raleigh. NC
William L, Lowe. Jr.. .M.D.. Winnetka. IL
Christine C, Mahvi. .M.D.. Middleton. Wl
E. John Markasheuski. Jr.. M.D.. Huntsville. AL
Steven K. .McCombs. M.D.. Chapel Hill. NC
T. Michael O'Shea. Jr. ,M.D.. Wniston-Salem. NC
Cort A. Pedersen. M.D.. Chapel Hill. NC
Dwight D, Perry. M.D, and Veronica J. Ray.
M.D.. Durham. NC
R. Brookes Peters IV. M.D.. Tarboro. NC
Bayard L. Powell. M.D.. Winston-Salem. NC
Timothy A. Presnell. M.D.. Richlands. VA
Pctnc M, Rainey. MD.. Lake Forest Park. WA
Judith L. Rissman. .M.D.. Lexington. MA
Steve E. Ritchie. M.D.. Knoxville.TN
Suzanne Rogacz. M.D.. Potomac. MD
J. McNeill Smith 111. M.D.. Asheville. NC
Paul C. Sorum. M.D.. Schenectady. NY
James P. Srebro. M.D.. Napa. CA
Walter J. Steele. M.D.. Charlotte. NC
Karin R. Sternberg. M.D.. Pittsford. N\'
Leslie L. Taylor 111. M.D.. Smithfield. NC
James V Taylor III. M.D.. Wilson, NC
Donna W. Tilson. M.D.. Louisville. KY
Jonathan P. Tolins. M.D.. Minneapolis. MN
Margo F, Tolins-Mejia. M.D.. Minneapolis. MN
Liliana Ci. Visscher. M.D.. Cape Girardeau. MO
Kenneth W. W ilkins, Jr., M,D., New Bern. NC
CLASS OF 19S1
Number in Class: 159
Percent Donors: 32.7%
(;. Williams .4dams. M.D. and Deborah L.
Fussing. .M.D.. Scverna Park. MD
Lee P Adlci. M.D.. Winsion-Salem. NC
Paul S. Andrews. M.D.. Chapel Hill. NC
David Shields Barnes. M.D. and Elizabeth Scott
Babcox. M.D.. Shaker Heights. OH
Craig R. Bennett. M.D.. North Wilkesboro. NC
Philhp M, Bridgman. MD.. Hannawa Falls. NY
Stephen E. Buie. .M.D,. Asheville. NC
(iraham W. Bullard. M.D.. Cornelius. NC
Lena W, Butterworth. .MD,. Charlotte. NC
David .4. Crews. M.D. and Elizabeth A. Eagle,
.M.D.. (Jreensboro. NC
Deborah H. Davis. M.D,. Morganton. NC
David M. Deitz. M.D.. Olympia. WA
Amelia F Drake. MD.. Chapel Hill. NC
Frederick M. Dula. Jr.. M.D.. Salisbury, NC
David A. Goff. M.D.. Raleigh. NC
David K. Harper, M.D.. Concord. NC
William M. Herndon. Jr.. M.D.. Charlotte. NC
G. Wallace Kernodle. Jr.. M.D.. Burlington. NC
Douglas P Kiel. M.D,. Medfield. MA
Garland C, King. MD,. Franklin. NC
Alan S. Kopin, M.D., Wellesley Hills. MA
R. Wayne Kreeger. M.D.. Atlantic Beach. FL
Leigh S. Lehan. M.D.. Raleigh. NC
Robert E. Littleton. M.D.. Raleigh. NC
Nanetta B, Loue-Roache. M.D.. Winston-Salem. NC
Jane E. Lysko, M.D., Asheville. NC
Saundra A. Maass-Robinson. M.D.. East Point. GA
John R. Mangum. M.D.. Sanford. NC
W illiani H. Menvm. Jr.. M.D. and Man -Frances
Meruin. Knowille. TN
Catherine H. Messick, M.D.. \\ iaston-Salem, NC
Charles B. Nemerot=l'. M.D.. Ph.D.. .AUanta. G.-\
J Thomas Newton. M.D.. Clinton. NC
Larry C. Nickens. M.D.. Goldsboro. NC
William B. Olds. M.D.. Rovboro. NC
Paul M. Parker. M.D. and Ruth M. Parker.
.\I.D.. .Atlanta. G.\
Peter L. Pleasants. M.D.. Providence. RI
Larn, B. Poe. M.D.. Binghamlon. NY
Teresa A. Rummans. M.D.. Rochester. MN
Timothy G. Saunders. M.D.. Charlotte. NC
Thomas J. SeeK. .\I.D . Summerfield. NC
Ehvood E. Stone. Jr.. M.D., Cedar Rapids. \.\
William W. Stuck. .M.D.. Columbia. SC
James D. V\hinna. M.D . Monroe. NC
.Susan M. Whitehead. Mancos. CO
Carol J. Wilkerson. M.D.. .Alexandria. V.-\
Phillip M. Williford. M.D.. Winston-Salem. NC
Warden L. Wbodard III. M.D.. Charlotte. NC
Michelle H. Wynn. M.D. and Ossian B. Wynn.
M.D.. Charlotte. NC
CL.XSSOF 19S:
Number in Class: 153
Percent Donors: ILf^t
John C .Adams. M.D.. Indian Trail. NC
Joseph L. Albright. Jr.. M.D.. Chariotte. NC
.Mary John Ba\le\. M.D . Greensboro. NC
Barbara L. Bethea. .M.D.. Lillinglon. NC
Peter H. Bradshaw. M.D.. Hickory. NC
J. Lawrence Brady. Jr.. M.D.. Charlotte. NC
David W. Cash. M.D.. Statesville. NC
N.incy C. Chescheir. NLD.. Chapel Hill. NC
Bruce V. Darden II. M.D.. Charlotte. NC
Robert C. Dellinger. Jr.. M.D.. High Point. NC
Cindy S. Dieringer. M.D.. Camden. SC
Lawrence M. Fleishman. M.D,. Charlotte. NC
Charles J. Fulp, Jr.. M.D.. Atlanta. GA
John S. Gaul III. M.D.. Charlotte. NC
Thomas W. Graham. M.D.. Carrboro. NC
Stephen .M. Hux. M.D.. Winston-Salem. NC
Timothy O. Jenkins. .\I.D.. Concord. NC
Beverly N. Jones III, M.D.. Winston-Salem. NC
Kathi J. Kemper, .M.D.. Boston. MA
Angela Kendnck. .M.D.. Aloha. OR
Virginia E. Killough. M.D.. Marquette. Ml
Marian S. Kirkman. M.D.. Carmel. IN
Vincenl J, Kopp. M.D . Chapel Hill. NC
.Mary I. Korytkouski. .\I.D., Pittsburgh. P.A
Jackie A. Lucas. M.D.. Charlotte, NC
James T. Massagee, M.D.. Greensboro, ,NC
Linville M. Meadows. M.D.. Jacksonville. FL
Horace W. .Miller IV, M.D.. Fayelteville, NC
Myrlin L. Murphy, M.D.. Chapel Hill. NC
Mark D. Peacock. M.D.. Mooresville. NC
Donald W Peters. M.D . VSinstonSalem. NC
Rildia J. Pritchelt. M.D.. Gary. NC
Eric D. \an Tassel, M.D.. Asheville. NC
Kathryn I,. VVeise. M.D.. Cleveland Heights. OH
Stanley A. Wilkins, Jr. M D . Raleigh. N(
(I \SSOF IW.^
Number in Class: 157
Percent Donors: 2l.T7r
David J Ballard. Ml).. Ph.D.. Dallas. TX
Thomas W. Benton. M.D.. Charlotte. .NC
Marsha F Benholl, .M.D . Jacksonville. FI.
James A. Bryan 111. M.D.. Chapel Hill. NC
\incenl K. Cheek. M.D.. Greensboro, NC
Douglas W, Clark. M.D . Chapel Hill. NC
R. Caner Clements. M.D.. Oakland. CA
Ronald W. Cottle. .M.D.. Florence. SC
.Mark H. Davis, M.D.. Crescent City, CA
Mary Anne Dooley, M.D.. Chapel Hill. NC
Nancy L. Earl. M.D., Chapel Hill, NC
James L. E\erette. Jr.. M.D.. Dover. DE
.\Iich.iel B, Fischer. M.D,. Glastonbury. CT
kimberly S, Haltiw anger. MD,. Scl.iuket. NY
John .M. Herion. M.D.. Wilmington. NC
Thomas T. Hunter. M.D.. Jacksonville. NC
Barbara E. Johnston. M.D.. New York. NY
Elizabeth Kopin. M.D..Wellesle> Hills. MA
James D L.idd. MD.. Ashe\illc. NC
Peter J, Larson. M.D,. Oakland. CA
Franklin Webster Maddux. MD, and Dugan
Wiess .Maddux. .M.D.. Danville. VA
Ovela B. Mcintosh- Vick. M.D.. Durham. NC
Margaret N. Morris. M.D.. Asheville. NC
James C, Osborne. M.D.. Greensboro. NC
Catherine C. Pamsh. MD.. Ellicott City. MD
Gail L, Shau, M.D., Odessa. FL
Hermon W. Smith 111. M.D.. West Friendship. MD
Eugene R. Soares. M.D,. Dover. NH
C. Stephen Stinson. M.D., Winston-Salem. NC
Gregory .A. Underwood. M.D.. Charlotte. NC
Mary C. Wasko. M.D.. Pittsburgh. PA
John H, Williams. M.D.. Raleigh, NC
Lawrence M. Wyner. M.D.. Charleston. WV
Princess W. Yousem, M,D,. Pittsburgh. PA
CLASS OF 14S4
Number in Class: 144
Percent Donors: 29.9 '7<^
James P Alexander. Jr.. MD,. Decatur. GA
D. Antonio Bell. M.D. and Amelia K Bell. .M.D..
Cornelius. NC
Steven J. Citron. M.D.. Dunwoody. GA
Patncia F Culhane. M.D., Campbell. CA
.Alain T. Drooz, M.D.. Vienna. V.A
Eli D. Finkelstein. M.D.. Edison. NJ
Kathleen J. Foster-Wendel. MD,. Ames. lA
Siephen h, Gitelman. M D,. San Francisco. CA
Ronald \>. Hargrave. M.D.. Mt. Pleasant. SC
James R. Harper. Jr.. .M.D.. W ilmington. NC
James C, Hill. M.D.. Cary. NC
Janice R. Hossler. M.D.. Columbia, SC
Linda E, Jafte. M.D.. Wilton. CT
Paul A, James. .M.D,. Williamsville. N'l'
.Michael J. Knight. M.D.. North Hampton. NH
Marcia A. Koomen. M.D., Chapel Hill, NC
Elizabeth W. Koonce, M.D.. Charlotte. NC
Robert P. Lineberger. M.D and Catherine K
Lineherger. M.D.. Chapel Hill. NC
Jo .M, Mailiirano. MD,. lexinglon, SC
Jane H. Murray. M.D.. Durham. Nl
Howard W. Newell. Jr.. .M.D.. Goldsboro. NC
R. Claiborne Noble. M.D.. Raleigh. NC
Douglas W. Peed. M.D.. Chapel Hill, NC
Ronald E. Pruitt. M,D„ Nashville. TN
Allred L. Rhyne 111. ,M.D . Charlotte. NC
Richard (;. Saleehy. Jr.. M.D. and Jackie A.
Niwlin-Saleeln. M.D.. Raleigh. N(
Kolvn ,\ S.iiiiiii(.ns. Ji . MD, (ii.iikl Junciion.CO
David I.. .Sappenfield. M.D.. Durham. N(
Paul W Sassei. MI). Lden. NC
.Mary A Saunders, NLD., Springfield. IL
John .\1 Schollstall. M.D.. Glen Mills. PA
Thomas E. Shook. M.D.. Savannah. (J.A
Thomas C. Spangler. M.D.. Winst<m-Salem. NC
Sharon R. Stephenson. M.D.. Cary. NC
Nathan R. Strahl. \1 I) . Ch.ipel Hill, NC
Paul E. Viser. M.D.. t linton. NC
Robert A. Wainer. M.D.. (ireensboro. NC
Rolf B. WaUin. M.D.. Fayelteville. NC
Robert E. Wiggins. Jr.. M.D,. Ashe\ille, NC
Daniel W. Wilhams 111. M D.. Lewisville. NC
CLASS OF iyS5
Number in Class: 159
Percent Donors: ^.^..^'^i-
A, Elizabeth Allen. M.D . Winsum-Salem. NC
Sebastian R, Alsion. M D,. Jackson. GA
S. Leonard Auman. Jr.. M.D.. Dallas, TX
Leslie A. Bunce. MD,. Ch.ipel Hill. NC
Charles L, Carter. M.D.. Memphis. TN
Kathleen M. Clarke-Pearson. M.D.. Chapel Hill. NC
Jonathan S. Cohen. M.D.. Signal Mountain. TN
Susan L. Cookson, M.D.. Stone Mountain. GA
Laura L. Crow. MD.. Greensboro. NC
Cynthia H, Dent. M.D.. Cro/et. VA
Douglas S. Diekema. M.D,. Kenmore. W.A
Cymhia B Dunham. M.D.. Chapel Hill. NC
Douglas Shure Feltman, NLD. and Gwenii
Elizabeth McLaughlin. M.D., Miami, FL
Kenneth E. Ferrell. Jr.. M.D.. Charlotte, NC
Margaret K, Fikrig. M.D.. Guilloid. CT
Catherine G. Fuller. M.D.. Los Angeles. CA
John H. Gilmore, Jr.. MD.. Chapel Hill. NC
Pamela P. Golden. M.D.. Tucson. .AZ
Charles S. Hayek. M.D.. Shelby. NC
Brentley D. Jeffries. M.D.. Ashev ille. Nt
Margaret G. Johnson, M.D.. C hapel Hill. N(
Stuart HaiTington Jordan. MD, and Sher\l Ann
Gillikin. M.D.. Fayetteville. NC
Dr. Peter M. and Mrs. Rebecca A, Jordan.
Greensboro. NC
David C. Joslin. MD,. Greensboro. NC
Theodore C. Kerner, Jr.. M.D., Lewisville. NC
John A, Kirkkind. Jr. M.D.. Charlotte. NC
Mark H. Knelson. M.D.. Durham. NC
Joyce K. Lammert. MD . .Senile. \\A
James W, Ledeiei. Jr. MD . Ad^.ince. NC
Elizabeth S. McCuin, M.D.. Roanoke. \A
Nancy H .Miller. .M.D.. Longmeadow. MA
Stephen B. Mitchell. M.D.. Moiehead. KY
Terrence D. Morton. Jr. M.D.. Moorcsville. NC
Albert R Munn 111. M D .ind Iis.i F Deiaincllc.
M I) . Raleigh. NC
Robert F. .Murray III, .M.D.. Pleasant Ridge. Ml
Albert J. Osbahr III, M.D., WaynesMlle. NC
Leslie K. Paulus. M.D.. Phoenix. A/
Fredertck B, Payne. Jr. MI). Fayelle\ illc. NC
Joel K. .Schneider. M.D.. Raleigh, N(
Martin E, Slieline. .MD . Allanla. <,A
McCriieS. Smith. Ml) and Haibai.i II Sniilh.
M.D.. Greensboro. NC
G King Snyder. Jr.. M.D.. Rye. CO
S. Patrick Stuart. Jr.. M.D.. Winston-Salem. NC
Dorothy E. Thomas, M.D.. LouismMc. K'i
Claudia L. Thomas. M.D.. Sands Point. N^l'
Bradley K Wcisiier. .MD,. Ch.irloite. NC
Randall W Williams. MI),. Raleigh. NC
Robert S /.uckei. Ml). lampa. FL
Sheine i;, /weig. MD,. Chapel Hill. NC
(1 \SS (1| I'ISf)
NinnlH-r in (lass: 155
35
I'erctnt Donors: 16.8'7f
Sic\en J. Baumrucker. MD.. Church Hill. TN
J Lancaster Bridgeman. Jr.. M.D.. Greenville, SC
M. Todd Brown. M.D.. Charlotte. NC
Charles B. Cairns. M.D.. Denver. CO
Michael D. Carter, M.D. and Mary Beth A.
Carter. M.I)., Wilmington, NC
James W Cheek. M.D., Jacksom lUe. FL
William M. Clark. Jr. M.D. and Elizabeth T.
Clark. M.D.. Oak Park. IL
Herbert (J. (iarrison HI, M.I) and Lynne C.
(iarrison, M.I)., (Jreenville, \C
hh/abeth V. Getter. .M.D.. New 'lork. N"!
Pamela G. Hanna, .MD., Cornelius. NC
Connie D. Hamll. M.D.. Indianapolis. IN
,). Curtis Jacobs, .M.D., High Point. NC
Jonathan K. Le\ine. M.D., Charlotte, NC
Leslie C. McKinney. M.D.. Raleigh. NC
Michael E. Nonns. M.D.. M.PH.. Greensboro. NC
.Steven R. Olson. M.D.. Greensboro, NC
C. W. .Sotley. Jr., M.D.. Anderson, .SC
Cathy Jo W. Swanson, M.D., Roanoke, V.A
Beverly J. Waddell, M.D., Lorton, VA
L. Tyler Wadsworth III, .M.D. and Deborah T.
Wadsworth, .M.D., Des Peres, MO
CaKin G. Warren, Jr, M.D.. New Bern. NC
James C. Womble. M.D.. Car>. NC
CLASS OF 14,S7
Number in Class: 156
Percent Donors: 30.1%
Steven H. Baker. M.D.. Asheville, NC
Thomas H. Belhom. M.D.. Ph.D. and Linda R.
Belhorn. M.D., Chapel Hill. NC
William S. Blau. M.D.. Ph.D.. Chapel Hill. NC
David W. Boone. M.D.. Raleigh. NC
Mehssa W. Bureh. M.D.. Orono. ME
Lisa A. Chnstman. M.D.. Raleigh. NC
(;regor (J. Cleveland, .M.I).. Ph.D..
TInimonsville, SC
James B. Collawn. M.D.. Raleigh, NC
Carey G. Cottle. Jr.. M.D.. Greensboro. NC
James Earl Crowe. Jr. M.D. and Elizabeth H.
C"rowe. M.D.. Brentwood. TN
Lochrane G. Davids, .M.D., (Jreenville, SC
I. Gordon Early. Jr. M.D.. Spartanburg. SC
Lee A. Furlong. M.D.. Seal Rock. OR
Jani.i B. Greene. M.D.. Rock\ Mount. NC
W Slu.irt Hartlc>. M.D.. Charlotte. NC
Richard H. Havunjian, M.D., Los .Angeles, C.\
James P. Hoolen. Jr.. M.D.. Elon College. NC
Dennis N. Jacokes. M.D. and Allison L. Jacokes.
M.D.. Raleigh. NC
William W, King. M.D.. Wilmington. NC
Thomas E. Lawrence. M.D.. Greensboro. NC
Susan R. Leiw. M.D.. Roanoke. \'.\
Ciusta\ C. .Magrinat. NLD.. Greensboro. NC
Teresa B. .Vlelvin. M.D.. Moores\ille. NC
Sherry L. Morris, M.D., Harrisonburg, \A
Peter R. Muller. NLD.. Charlotte. NC
Lisle M. Nabell. M.D.. Bimiingham. AL
Thomas E. Paulson. M.D.. Sacramento. CA
Nancy \\. Phifer. M.D., Burlington, NC
Mark K. Robbins, M.D., Charlottesville. VA
David B. Robinson. M.D.. M.RH.. Auke Ba\, AK
C. Alan Ross, M.D., Summerfield. NC
Daniel M. Sappenfield. M.D.. Charlotte. NC
Constance J. Sewell. M.D.. Asheville. NC
Ronald B Shapiro. M.D.. Austin. T.\
Da\id L. Sheppard. M.D.. Gull Breeze. FL
36
Robyn L. Stacy-Humphries, M.D., Charlotte, NC
Brian S. Strauss. .M.D.. High Point. NC
William R. Sutton. M.D.. Wilmington. NC
Victoria B. Teague. M.D.. Alpharetta. G.\
Obinnaya C. Umesi. M.D.. Durham. NC
Roben M. Walasin. M.D.. Chapel Hill. NC
Da\id C. Ward. M.D.. Chapel Hill. NC
Jonathan J. Weiner. M.D.. Durham. .NC
Paul A. 'loung. M.D.. APO. AE
CLASS OF 19SS
Number in Class: 154
Percent Donors: 27.9%
C. Trent Blackman. M.D.. Concord. NC
Jon P. Brisley. .M.D.. Roanoke. \ A
Brenton T. Burkholder. M.D.. Atlanta. GA
J. Craig Charles. M.D.. Winslon-Salem. NC
Jack .M. Cole, M.D., Moore, SC
Debra L. Coles. M.D.. Charlotte. NC
Jonathan B. Covey. M.D.. Pueblo, CO
Peter G. DalldorL M.D.. Greensboro, NC
Keith A. Davis, M.D., San Diego, CA
Paul R. Eason, M.D. and Margie B. Eason, M.D.,
Martinsville, V.A
C, Gaelyn Garrett, M.D., Nashville. TN
Kirslen G. Girkins. M.D.. Charlotte. NC
Frenesa K. Hall. .VLD.. Lilbum. GA
Elizabeth H. Hamilton. M.D.. Chapel Hill. NC
Da\id W. Herion. M.D.. Bethesda. MD
Hunter A. Hoover. M.D.. Charlotte. NC
C. David Johnson. M.D.. BIythewood. SC
Kathryn P. King, M.I)., Carrboro, NC
Hannah R. Krigman, M.D., St. Louis, MO
Ritsu Kuno. M.D.. .Midlothian. VA
Jane M. Laco. .M.D.. Plymouth. MN
Stuart J. Levin. M.D.. Raleigh. NC
Thaddeus L. McDonald III. M.D.. Raleigh. NC
Marsden H. McGuire. M.D.. Baltimore. MD
Philip J. Nahser. Jr. .M.D.. Greensboro. NC
Charles E. Parke, M.D., Greenville. SC
Richard M. Peek. Jr. M.D. and Julie T Peek.
M.D.. Nashville. TN
Gary L. Pellom. M.D.. Durham. NC
John E. Perry III. M.D.. Raleigh. NC
H. Kyle Rhodes. M.D.. Wilmington. NC
Jeffrey E. Roller. M.D.. Morganton. NC
George H. S. Sanders. M.D.. Jamestown. NC
Charles D. Schcil. M.D.. Hickory. NC
J. Robert Siher. M.D.. Charlotte. NC
Mary E Smith. M.D. and Bryan W. Smith. M.D..
Chapel Hill. NC
Daniel J. Stackhouse, M.D., Charlotte, NC
John D. S\ nianski. M.D.. Charlotte. NC
Roger P Tart. M.D.. Mobile. AL
Edward W. Whitesides, M.D., Wilmington, NC
Elliott E Williams. M.D.. High Point. NC
CLASS OF 1 y.s^
Number in Class: 146
Percent Donors: 24.0%
Paul E. Austin. M.D.. Durham. NC
Scott M. Baker, M.D. and Kristin D. Baker,
M.D.. Concord, NC
Robert S. Bein, M.D., Green\ille. TN
L. Katheiine Bliss, M.D., Etland, NC
Lisa K. Burke, M.D.. Marietta. GA
.Margaret F. Campbell. M.D., Greensboro, NC
Peter N. Copsis. M.D., Matthews, NC
Brcnda K. Cowell. M.D.. Charlotte. NC
Daniel T Goulson. M.D.. Levinsiton. K^'
Douglas B. Hansen. M.D.. Rock Hill. SC
Mary E Hebert. M.D.. Denison. T\
Rosemary Jackson. M.D.. Bahama. NC
Daniel M. Kaplan, M.D., Raleigh, NC
Michael W. Keeley. .M.D.. Shelby. NC
William H. Kelly. M.D.. Fayetteville. NC
Charles G. Lampley IV. NLD.. Shelby. NC
William L. Lawing. M.D.. Winston-Salem. NC
Johnnie A. Lee. M.D.. Fuquay Varina. NC
Kenneth S. Maxwell. M.D.. Winston-Salem. NC
James M. McLean. M.D.. Winston-Salem. NC
Melissa M. McLeod. M.D.. Norfolk. VA
Jay B. .Michael. M.D.. Fayetteville. NC
H .Merle Miller. M.D.. Boulder. CO
Linda K. .Mitchell-Fry e. M.D.. Laurel. NC
Robert F Noel. Jr.. .VLD.. Henderson. NC
Lisa C. Richardson. M.D.. Clarkston. GA
Mary D. Shearin. M.D.. Jamestown. NC
Arthur J. Shepard III. M.D. and
Nicole P Shepard. M.D.. Albany. GA
Ci. Bradley Sherrill. M.D.. Greensboro. NC
Patricia G. Singer. M.D. and J. Daniel Singer.
M.D.. Greensboro. NC
John H. Stephenson. M.D.. Roswell. GA
Jon R Woods. M.D.. Madison. Wl
CLASS OF \W{)
Number in Class: 153
Percent Donors: 30.7%
Lori W. Balahan, M.D.. Charlottesville. VA
John E. Barkley. M.D., Charlotte. NC
Ronnie J. Bamer. M.D.. Salisbury. NC
Elizabeth D. Bell. M.D.. Chapel Hill. NC
Robert M. Bernstein. M.D.. Seattle. WA
Anna P Bettendorf. M.D.. Durham. NC
Cednc M. Bnghl. M.D.. Durham. NC
Betsy E. Brown. M.D.. Seattle. WA
Martyn J. Cavallo. M.D.. Nash\ ille. TN
Sandra C. Clark. M.D.. Chapel Hill. NC
Scott M. Cochrane. M.D.. Amherst. MA
Catherine L. Cooper. M.D.. Richmond. V.A
Todd S. Cowdery. M.D.. Eastsound. WA
C. James Cummings. M.D.. .Asheville. NC
Terri W. Cummings. M.D.. Stone Mountain. GA
William De Araujo. .M.D.. Goldsboro. NC
Ban-y T Degregono. M.D.. Portland. OR
Jon P Donnelly. M.D.. Cape Elizabeth. ME
Thomas E Edwards. Jr. M.D.. Atlanta. GA
Robert R. Ehinger. .M.D.. Greensboro. NC
John W. Entwislle III. M.D.. Lafayette Hill. PA
Mary I. Fatehi. M.D.. Englewood. NJ
.Mark T. Hooten. M.D.. Rock Hill. SC
R. Lynne Homsby. M.D.. Greenville. SC
Stacey N. Ibrahim. M.D.. Asheville. NC
Dominic .A. Jaeger. M.D.. Burlington. VT
Leigh H. Jones. M.D.. Greensboro. NC
John H. Kiege. M.D.. Greensboro. NC
Philip C. Lackey. M.D. and Victona D. Lackey.
M.D.. Charlotte. NC
Edward I. Lee. M.D.. Winchester. VA
Lon B. Lilley. M.D.. Raleigh. NC
Linda J. Matthews. M.D.. Huntersv ille. NC
Nicolette B. Naso. M.D. and William B. Naso.
.M.D.. Florence. SC
Todd G. Owsley. DDS. M.D.. Greensboro. NC
Whitman L. Reardon. M.D.. Chapel Hill. NC
J. Gardiner Roddey. Jr. M.D. and Patricia K.
Rodde\. M.D.. Charlotte. NC
Ami J. Shah. M.D.. South Pa.sadena. CA
Eugenia B. Smith. M.D.. Chapel Hill. NC
Murphy F Townvend III. M.D.. Atlanta. G.A
Craig W ierum, M.D.. Nashville, TN
J. Todd Williams. M.D.. .Asheboro. NC
.Adam S. Wilson. M.D.. \ancou\er. \\.-\
John H. Wood. M.D.. Chapel Hill. NC
Mark W. Zimmerman. M.D and
Sherri .A. Zimmemian, M.D.. Car>. NC
CL.-XSSOF 1441
Number in Class: 157
Percent Donors: 24.8'>
Katrina H. .Avery, M.D.. Durham, NC
Mack N Barnes III. M.D.. Bimiingham, .\L
Roben P Bnaht. M.D., Durham. NC
Roben C Brooks. M D . Pittsburgh. P.A
N. Elaine Broskie. M.D.. Salem. OR
M. Elizabeth Brown. .\I D.. Summert'ield. NC
Linda H Butler. M D . Raleigh. NC
Thomas R. Coleman. M.D.. Lut/. PL
Roben L. Cook. M.D.. Pittsburg. P.A
William W. Crone. M.D.. .Atlanta. G.A
Amy C. Degnim. M.D.. Leeds. M.A
Cathenne M. Gordon. M.D.. Wellesley. M.A
Bnan H. Hamilton. M.D.. Charlotte. NC
Leon W, Hemdon. Jr. M.D. and
^olanda \'. Scarlett. M.D.. Hillsborough. NC
W Barlou Inabnet III. M.D.. Neu fork. NY
l)re« A. Jones. M.D.. Greensboro. NC
Seth E. Kat/. M.D.. San Diego. C.A
W P Killam. M.D.. Fort Defiance. .AZ
.Michael J. Lucas. M D.. High Point. NC
Constantine G. Marousis. .M D . West Palm
Beach. FL
James J. McCarthy. M.D.. Menon Station. PA
Todd D. McDiannid. M.D.. Greensboro. NC
Scott R. McDuffie. M.D.. Sumter. SC
Jobe C. Metts 111. M.D.. Mount Pleasam. SC
Linda M, Nicholas. .M.D.. Chapel Hill. NC
Vincent C. Phillips. M.D.. Engleuood. OH
Richard J, Pollard. M.D. and
Helene R Keyzer-Pollard. M.D . Gastonia. NC
Danny Silver. M.D.. Raleigh. NC
Bnan D. Smith. .M.D.. Shelby. NC
Todd F Tanner. .M.D.. Goldsboro. NC
Paul C. Tobin. M.D. and Rebecca B Tobin, Ml).
Chapel Hill. NC
Gilbert R. Upchurch. Jr. M D . Ann .Arbor. .Ml
Andrew B. Wallach. .M.D.. New York. NY
Frederick M. Weeks. M.D. and Margaret W.
Weeks. M.D.. Vero Beach. FL
Patrick .A. Wilson. M.D.. Wihnington. DE
Edward H. Wrcnn. M D.. Pittsburgh. PA
CLASS oi- iw:
Number in Class: 157
I'lrcint Donors: 2(1. -I'r
Jorge A Allende. Jr. M.D . Fort Collins. CO
Mary M, Bledsoe Felkner. M.D.. Charlotte. NC
Lisa A. Brone. .M.D.. .Abescon. .NJ
Nancy C. Clayton. M.D.. Chapel Hill, NC
Gerald E. Cooley. M.D. and Amy R. Cooley.
MD. Charlotte. NC
Christopher C. Cosgrose. M D. and
Billie F Cosgrove. M D . Wilmington. NC
Cynthia K. Crews. M.D . Den\er, CO
Mary J. Forbes. M.D.. Raleigh. NC
Scolt K. Garrison. M.D.. Raleigh. NC
James G. Hall. .M.D.. Durham. NC
Mark W. Jenison. M.D.. Virginia Beach. VA
Pamela C. Jenkins. .M.D.. Lvmc. NH
Andy C. Kiser. M.D., Whispering Pines. NC
Ban-etl T. Kitch. M.D.. Cambridge. MA
David A. Konanc. M.D.. Raleigh. NC
Susan R. Marcinkus. .M.D.. Luther\ille. MD
Walter S. Moms III. M.D.. Southern Pines. NC
Martin T. Noveinber. M,D.. Cambridge, M.A
Edward J. Pnmka 111. M.D, and Lynda R. Pnmka.
M D. .A\onLake. OH
Anand \'. Ramanathan. M.D.. Darien. IL
Hans P Roethlmg. M.D.. C.oldsbor,.. NC
J Cullen Riitl. M.D.. Arlington. \A
Scott \'. Smith. .M.D.. Ape\. NC
Anjali M. Sues. M.D.. Raleigh. NC
Thor O. Svendsen. M.D.. Chariottc, NC
Rita E. Treanor-Plemmons. M D.. Envin. TN
Charles D. Wells. M.D.. Atlanta. GA
Bradford Tracy WinsKm. M.D, and Lisa Corbin
Winslou. MD.. Denver. CO
CLASS OF IW,^
Number in Class: 145
Percent Donors: 21.4'<-
Aleta A, Borrud. M.D,. Rochester. MN
Rochelle M, Brandon. M.D.. Charlotte. NC
Tamara W, Bnngewatt. MD,. Davidson, NC
Harry L. Broome. Jr.. M.D.. Phoeniv. AZ
John S. Chase. M.D., Iowa City. lA
John D. Corey. M.D.. Carrboro. NC
William L. Craig III. M.D.. Raleigh. NC
Carolyn J. Dalldorf. M.D.. Chariottesville. VA
Karia L. Debeck. .M.D.. Durham. NC
Cathy .A. Donovan. .M.D.. Onainia. MN
S, Lynn Gardner. M.D.. Stone Mountain. G.A
J. Judd Green. Jr. M.D.. Jamestown. NC
Thomas M. Haizlip. Jr. M.D.. Banner Elk. NC
Joseph 1, Harwell. .M.D.. Sharon. MA
C. Anthony Kim. M.D.. Puyallup. WA
Eugene H, Maynard. Jr. M.D.. Smithfield, NC
Jennifer L. Miles, M.D.. Oakland. CA
John D. Phipps. M.D.. Winston-Saleni. NC
Lawrence M. Raines III. MI),. Chapel llill. NC
Eileen M. Raynor. MD,. J.icksonville. II.
Norman E. Sharpless. M.D,. Newton. M.A
Tammy R. Spear, M.D.. Summert'ield. NC
Eric S, Stem. M.D.. Fort Wayne. IN
Theodore T. Thompson, M.D,. .Abingdon, V.A
Loretta K, Tibbels, M.D,. Omaha. NE
Paige C, Walend. MD,. Phoenix. AZ
Lisa 1. Wang. M D,. Houston. T\
Bruin R Webster. MD,. Wilmington. NC
William K. Westerkam. M.D., Coliimhia. SC
Kirk I., Wooslev. MD,. Ch.irlotte. NC
MehndaT, Wvatl. MI). Raleigh. NC
CT.ASSOF IW4
Number in Class: 153
Percent Donors: 21,6'^^
Jonathan G Austin. Ml). Moiini I'lc.isanl. SC
Laura H, Bachniann, M.I), and Kurt C B.kh
mann. MD,. Birmingham. AL
.Mary T. Bond. .M.D.. Fayelteville. GA
Jane H. Brice, M.D., Chapel Hill. NC
Marlene S. Calderon. MD.. Ypsilanii. Ml
Peter T Chu. M.D . Fletcher. NC
Lisa A. Ciillespie. M D . l.ithonia. GA
Robin P B Hicks. .M.D., Newton Highlands. MA
Chandra S Hollier, M.D.. Carol Springs. 11.
William H Jones. M.D.. Charlotte. NC
Carrie S. Kent. M.D.. Lenoir, NC
Kenneth C. Lcnnon. M.D.. Greenville. S(
Roy S Lewis. M D,. Houston. T\
Melissa M, Luiz. MD,. Chapel Hill. NC
John L. Matthews. M.D.. Durham. NC
Karen F, Mattocks. MD.. Columbia. SC
Lucy S. Miller. M.D, and Robert Sean Miller. Jr.
M.D. Cincinnati. OH
Jacqueline H, Minis. Ml) and J, W hitman Minis.
Ml). Winston Salem. NC
l),iniel H. Moore. Ml). Ches.ipe.ike, VA
Juha E, Norem-Cokei. Ml),. Favetteville. NC
John B Patterson. MD . PhD . Winston-Salem. NC
William L. Plyler, M.D.. Hendersonville, NC
Claudia C. Prose, M.D.. Chapel Hill, NC
Lisa A. Rietz. M.D., St. Louis. MO
John W. Rusher, MD., Raleigh, NC
Richard Scherczinger, M.D.. Cornelius, NC
Nicholas B. Sliz. Jr. M.D.. Lawrenceville, TN
Carolyn T. Spencer, M.D., Gainesville, FL
Bristol R Winslow. MD . Durham. NC
Juhe L, Wynne. MD,. Milhnocket. MH
CLASS OF IW5
Number in Cla.ss: 174
Percent Donors: 24.1 T'c
.Mich.iel D, Applegate. M.D.. Asheboro. NC
Joshua E, Bernstein. M.D., Cambridge, MA
Paul H. Bowman, M.D., Augusta, GA
Peter A. Caprise, Jr.. M.D.. Chapel Hill, NC
Christina L. Catlett. M.D.. Ellicott City, MD
David A. Chesnutt. M.D.. Chapel Hill, NC
Elizabeth C. Deterding. MD,. Summertleld. NC
Andrea B Dickerson. .M D . Favetteville. NC
Elisabeth K, Dipietro. MD,. Weston. .MA
David B. Dorofi. M.D.. Norfolk. VA
Dietrich A. Gerhardt. M.D., Waterloo. LA
Richard Ryan Gessner. M.D and Sarah Young
Gessner. M.D.. Charleston, SC
Kathcnnc Meadows Harper. M.I), ,iiid Stephen A.
Harper. MD,. Clemmons. NC
Marcus T, Higi, M.D.. Tallahassee. Kl.
John B, Holtzapple 111. M.D.. Eugene. OR
Richard H. Jones, M.D., Patuxent River, MD
Angela M. Keen. M.D., Salt Lake City, I'T
Suzanne Lazorick. M.D.. Clayton, NC
A. Kellett Letson 111. Ml).. Asheville. NC
William D. Lyday II. .M.D,. Omaha. NF
Brant K. Oelschlager. MD,. .Seattle. WA
John W. Ogle 111, M.D., Palo Alto. CA
Hitcn K. Patel. M.D.. Charlotte. NC
Linda D. Pegram. M.D,. Philadelphia. PA
Monica L. Piecyk. M.D. and John B Piecyk,
M.D., Canton. MA
Laura M, Robert. M.D,. Lynchburg. \A
Paul D. Rosen. M D . New Voik. NY
Wesley G. Schooler. .\l I) , Duiham. NC
Susan K. Seo. .Ml). New York, N^
David R, Shaffer. Ml),. New York. NY'
C.inil G. Shores. M.D.. Chapel Hill. NC
D.ina L, Simpson, M.D , Charleston, SC
\ni.iiida 1. Slater. MI).. Pittsboro, NC
l< S Spies. Ml). Matthews, NC
Jawal Suleman. M I) . Colunibia, SC
John W Surles. M D . M,k Jesficld. NC
Ketan K. Iriveih. Ml). Alex.indna. \A
Kellv M. Waicus. Ml), Durham. NC
Deidra I. Woods. Ml). Washington. DC
CLASS OI I'f'lf,
Number in Class; 15'>
Percent Donors: 211. 1 ' i
37
Maa' Oregon Amaya. M.D. and Sharon Croom
Amaya. M.D.. Mableton, GA
Kathenne E. Barrett. M.D.. Raleigh. NC
David K. Becker, M.D.. Chapel Hill. NC
Andrea C. Best. M.D.. Culver City, CA
Sara B. Beyer. M.D.. Matthews. NC
Ann-Bndget D. Bird. M.D.. Durham. NC
Cynthia J. Brown. M.D.. Waterhury. CT
Christopher H. Chay. M.D.. Ann Arbor. Ml
William J. Conner. M.D.. Dunn. NC
Lorraine D. Comwell. M.D.. Carrboro. NC
Robert M. Dums. M.D.. Christiansburg. VA
Cory A. Dunnick. M.D.. Nashville. TN
Joan E. East. M.D.. Asheville. NC
Douglas K. Graham. M.D.. Highlands Ranch. CO
Brian Earl Grogg. M.D. and Karen Lynne Grogg.
M.D. Rochester. MN
.lames A. Haaksma. M.D.. .'\sheville. NC
Juhc A. Haizlip. M.D.. Chapel Hill. NC
Kimberly J. Hamilton. M.D.. Durham. NC
Chamette M. Huggins. M.D.. Washington. NC
E. Allen Liles. Jr.. .M.D.. Durham. NC
Michael H. Lowry. M.D.. Morehead City. NC
Daniel E Maher. M.D.. San Diego. CA
John E. Milko. M.D.. Myrtle Beach. SC
David P. Miller. Jr. M.D.. demons.. NC
Tracey E. O'Connell. M.D.. Durham, NC
David N. Quinn. M.D.. Columbus, OH
Lisa M. Roberts, M.D., Pittsburgh, PA
JettVy P. Simko, M.D., Ph.D.. San Francisco. CA
William T. Smith IV. M.D.. Durham. NC
Carlos A. Vargas. M.D.. Eranklm. NC
CLASS OF IW7
Number in Class: 161
Percent Donors: 41.(11-
Eyal C. Altar. M.D.. Biookline. MA
Henry C. Baggett III. M.D.. Anchorage, AK
Ihre/ R. Bandukwala. M.D.. Atlanta. GA
Michael L. Batten. M.D.. Philadelphia. PA
,'\ndrew William Ba/emore. M.D. and
.Anna Marlet Bazemore. M.D.. Cincinnati. OH
Kimherly L. Beavers. M.D.. Chapel Hill. NC
Kclurah C. Bell. M.D.. Kingsport. TN
George M. Brinson. M.D.. Chapel Hill. NC
Debbie A. Brown. M.D.. Southfield. MI
Michael B. Brumback. M.D.. Atlanta. GA
\Lirk D. Charlson. M.D.. Chapel Hill. NC
Stephen V. Chiavetta III. M.D.. Rochester. MN
Kathy N. Chism. M.D.. Knowille. TN
Elizabeth C. Clark. M.D.. Portland. OR
Raymond D. Cook. M.D.. Durham. NC
Nicole M. D' Andrea. M.D.. Chapel Hill. NC
Lance L. Davis. M.D.. Charleston. SC
Charles S. Dietrich 111. M.D.. Honolulu. HI
Carrie A. Dow-Smith. M.D. and Vincent C.
Smith. M.D.. Pearland. T.\
Charles W. Eitrig. M.D.. Miami Beach. FL
Janel R. Encamacion. M.D.. Springfield. MO
Thomas W. Gansinan. M.D.. Indianapolis. IN
Cathryn A. Geary. M.D.. Cincinnati. OH
Bradley C. Gehrs. M.D.. Birmingham. ."XL
Chandra S. Ghosh. M.D.. Atlanta. GA
Michael Gill. M.D.. Ann Arbor. MI
Leigh B. Goodwin. M.D.. Charlotte, NC
Todd E Griffith. M.D.. Durham. NC
Richard W. Hudspeth. M.D., Salt Lake City. L'T
Srikant B. Iyer. M.D.. Cincinnati. OH
Paul Harian Kartheiser. M.D. and .-Xmy Mane
Lrsano. M.D.. Durham. NC
38
Andrew L. Katz. M.D.. Durham. NC
Dawn E. Kleinman. .M.D.. Carrboro. NC
Jennifer S. Klenzak. M.D. and Scott M. Klenzak.
M.D.. Durham. NC
Ramesh L. Krishnaraj. M.D.. Greensboro. .NC
Kathryn A. Lee. M.D.. Etna. NH
Cindi J. Leech. M.D.. Salt Lake City. UT
Erica A Lyndrup. M.D.. New York. NY
Donna B. McGee. M.D.. Horse Shoe, NC
Leah R .Mc.Mann. .M.D.. Dupont. WA
Jerry W. Mitchell. Jr.. M.D.. Pittsburgh. PA
Dean S. Morrell. M.D.. Chapel Hill. NC
Amy L. Mosher. M.D.. Chapel Hill. NC
Jeffrey S. Moyer. M.D.. .Ann .Arbor. Ml
Julia K. Nelson. M.D.. Durham. NC
Brian S. OKelley. M.D.. Gainesville, FL
John Charles Parker. M.D. and
Heather M. Henderson. M.D.. Lexington. K'l'
Joseph F Penta. M.D.. FPO. AP
John K. Petty. M.D.. Portland. OR
Sarah B. Philp. M D.. .Seattle. WA
Jennifer E. Rhodes-Kropf .\LD.. New York, NY
Austin S. Rose. M.D.. Chapel Hill. NC
John R. Stephens. M.D. and Anne H. Stephens.
M.D.. Durham. NC
Julie C. Verchick. M.D.. Pinehurst. NC
Lauren E. Wagner. M.D.. Chicago. IL
Melanie P Walker, M.D.. Cincinnati. OH
Lydia Ward. M.D.. Charleston. SC
lllya L. Wilkerson. M.D.. Greensboro. NC
Christopher R. Williams. M.D.. Bimiingham. AL
Laura Clark Windham. M D.. Durham. NC
CLASS OF IWS
Number in Class: 152
Percent Donors: 34.2%
John G. Alley. Jr. M.D.. Carrboro. NC
Christopher W. Baird. M.D.. Pittsburgh. PA
Elizabeth R. Bates. M.D.. Berkeley. CA
Michelle W. Beckham. M.D.. Concord. NC
Dalliah M. Black. M.D.. Hillsborough. NC
Jacqueline C. Chang. M.D.. Na.shville. TN
Alan Cook. M.D.. Durham. NC
Christopher C. Copenhaver. M.D. and
Carol Anne Borack. M.D.. Rochester. NY
Mary S. Crowder. M.D.. Greenville. NC
James M. O. Culver. M.D.. Durham. NC
Farr A. Curlin. M.D.. Chicago. IL
Jason E. DeVente. M.D.. Greenville. NC
William F. Durland. Jr.. M.D.. Maple Bluff Wl
Jonathan E. Fischer. M.D.. Carrboro. NC
Maxwell E. Fisher. M.D.. Nashville. TN
Angela B. Gantt-Holliday. M.D.. Dublin. OH
Kathy L. Gariand. M.D.. Chapel Hill, NC
Barbara K. Gavin, M.D., Boston. MA
Nichole D. Gner, M.D., Chapel Hill. NC
Chad Gunnlaugsson. M.D.. Ypsilanti. MI
Joshua L. Hardison. M.D.. Cumberland. Rl
Paul M. Henderson. M.D.. Hendersonville. NC
Michael S. Hoben. M.D.. Charlotte. NC
Rebeccah A. Hoffman. M.D.. Monroeville. PA
Travis C. Honeycutt. M.D.. Norfolk. VA
Joseph T. Jenkins. M.D.. Chapel Hill. NC
Traci A. Lamothe. M.D.. Charlotte. NC
Miriam W. Lindrooth. M.D.. Northfield. IL
Colby E. Mangum. M.D.. Winston Salem. NC
Siobhan O'Connor. M.D.. Louisville. KY
Robert S. Park, M.D., San Francisco. CA
Stephen J. Phillips. M.D.. Baltimore. MD
William G. Pittman III. M.D.. San Francisco. CA
Caroline C. Prochnau. M.D.. Knoxville. TN
James M. Schmidt. M.D.. Charlotte. NC
Brian Shelley. .M.D.. .Albuquerque. NM
Mona A. Sinno. M.D.. Waco. T\
Shelia D. Smith. M.D.. Richmond. CA
Amy B. Stanfield, M.D.. Charlotte, NC
Thomas E. Stephens. .M.D.. Asheville. NC
William H. Sturgill III. M.D.. Jacksonville. NC
Andrew J. Taylor. M.D.. Wnghtsville Beach. NC
Stephan G. Thiede. .M.D.. Chapel Hill. NC
Michael M. Walger. M.D.. Loma Linda. CA
John W. Warner. M.D., Falls Church. VA
Elizabeth S. Weinberg, M.D., Cincinnati, OH
T Bnan Willard. M.D.. Columbia. MO
Paul L. Winslow III. M.D.. Durham. NC
Robyn K. Zanard. M.D.. Greensboro. NC
.Adam J. Zolotor. M.D. and Karolyn Forbes,
M.D.. Ann Arbor. MI
CLASS OF I9W
Number in Class: 133
Percent Donors: 27.1 '^f
Victor C. Archie. M.D.. Thousand Oaks. CA
Eric D Bernstein. M.D.. Portland, OR
Roben C. Bowen 111. M.D.. Charlotte. NC
Stephen P Brackbill. M.D.. Chicago. IL
Craig M. Bumworth. M.D.. Columbia, SC
Peggy A. Byun. M.D.. Winston-Salem. NC
H. Scott Cameron II. M.D.. Baltimore. MD
Nicole Chaisson. M.D.. Saint Paul. MN
John B. Chiavetta. M.D.. Rochester. MN
Ellen C. Collett. M.D.. Morganton. NC
Stanley R Dover, M.D., Winston-Salem, NC
Robert A. DuBose. M.D.. Seattle. WA
Carrie L. Dul. M.D.. Portland. OR
S Sheppard Dunlevie. Jr. M.D.. Charlotte. NC
Michelle E. Elisburg. M.D.. Kew Gardens. NY
Lisa A. Flora. M.D.. New Castle. DE
Robert G. Goodrich, M.D.. Chapel Hill, NC
Lisa J. Harrington. M.D.. Providence. RI
Angela L. Heider. M.D.. Chapel Hill. NC
Winny W. L. Hung. M.D.. Providence. Rl
Yewande J. Johnson. M.D.. Birmingham. AL
Kevin J. Logel. M.D.. Salt Lake City. UT
Marchi V. Lopez-Linus. M.D.. Chapel Hill. NC
Ben M. Meares. Jr.. M.D.. Taylors, SC
Brian H. Mullis. M.D.. Durham. NC
Stephen F. Parsons. M.D. and .Alden M. Parsons,
M.D. Chapel Hill. NC
LeVonne G. Powell-Tillman. M.D.. Durham. NC
Beth A. Renzulh. M.D.. Chapel Hill. NC
L. .Allison Shivers. .M.D.. Nashville. TN
Graham E. Snyder. M.D.. Manhasset. N\'
Julia W. Tsang. M.D.. Chapel Hill. NC
Harrison G. Tuttle. M.D.. South Burlington. VT
A. Elizabeth Undenvood. M.D.. Salt Lake City. UT
LaClaire Williams. M.D.. Tucson. ,AZ
Enc S. Winer. M.D.. Maiden. .MA
CLASS OF 2000
Number in Cla.ss: 142
Percent Donors: 4.2%
Albert M. Anderson M.D.. Chapel Hill. NC
Joshua W Knowles. Chapel Hill. NC
Cathenne T. Lee M.D.. Chapel Hill. NC
Zackary S. Moore M.D.. Chapel Hill. NC
Jeffrey S. Mueller M.D.. Chapel Hill. NC
Patrick A. O'Connell M.D.. Baltimore. MD
MEDICAL ALLIED HEALTH SCIENCES
GRADUATES
Duane S. Anderson. Jr.. Siaunlon. \A
Stephanie S. Baker. Car\. NC
Lon E. Benn. Chicago. IL
C\nthia P. Bodenheinier. Winston-Saleni. NC
Ehzabeth .A. Bridges. .Atlanta. G.\
Doreen E. Clark. Raleigh. NC
Cheri Courtright. Greensboro. NC
Sidney S. Curn,. M.D.. Norcross. G.A
Shan, n H. Davies. Little Rock. AR
Susan H. Davis. Gibsonville. NC
Jason M. Demon, Carrboro. .NC
.Alice S. Duddy. Fi^mingham. M.A
Laura H. Dudle\. Rocks Mount. NC
Chnst\ S. Engle. .\Iaitheus. NC
Bett\ B. Gast. Hickor\. NC
Patrice E. Hardee. .Moms\ille. .NC
Leslie C. Hawley. Corpus Christi. T.\
Michele M. Haywood. Columbia. SC
Christin L. Hemmens. New Orleans, L.A
Kathleen O. Hemdon. Raleigh. NC
Carol Higgins-Gilmer. Chapel Hill. NC
Catherine N. Humphrey. Bimungham. ,AL
June S. Kenned\. Durham. NC
Kimberls B. K.lug. .Menomonee Falls. WI
Sheila R. McMahon. Raleigh. NC
Cheryl E. Miller. Alpharetta. GA
Joelle M. Roberson. WiUiamsville. N^■
Darlene K. Sekerak. Ph.D.. Raleigh. NC
Patncia S. Sikes. Chapel Hill. NC
Christopher S. Throckmorton. .Atlanta. G.A
Kathenne P. Uomoto. Issaquah. W.A
BASIC SCIENCES GRADL ATES
Nils B. Ades. Ph.D.. Salt Lake City. LT
Carolme H. .Aland. Ste\ensville. .\1D
Patricia \\. Bair. .Marianna. FL
Enc T Baldwin. Ph.D.. Kalania/oo. .Ml
Christine A. Biron. Ph.D.. Pro\ idence. Rl
Dehra D. Bloom. Ph.D.. Sun Prarie. WI
Timoth\ J. Boiling. Wilmington. DE
Joan P. Boone. Efland, NC
Carl D, Bonner. Ph D. Durham. NC
Su/anne C, Bullock. Blowing Rock. NC
Janet P Burnham. Ph D . Raleigh. NC
Robert (ilenn Butler. Escondido. C.A
Karen E. Butler. Fredenck. MD
Mary G. Cafiero. Richardson. TX
Ian J Caley, PhD and Rebecca Pogue-Caley.
Ph D . Chapel Hill. NC
Ellen S. Cana\an. Cary. NC
Shery 1 K. Camiak. Bismarck, ND
Matthew E. Carrigan, Atlanta. GA
Chia S. Chang. New Hyde Park, NV
Kathry n K. Cheek. Columbus. GA
Qiming Chen. Ph.D.. Horsham. PA
Caroline M Christopher. Chapel Hill. NC
Nancy W. Clark. Reston. VA
Alison G. Comweil. Carrboro, NC
Iimothy W. Corrigan. Charlotte, NC
Debra K. Cowan. Chapel Hill, NC
Victoria Z. Coward, Jacksonville, FL
Merle M. Crawford. Hummelsiown. PA
Dorothv L Daley. Wilmington. DL
Robena M. Del.uca. Raleigh. NC
Martha W. Easlcy, Amelia Island. FL
Harriet H. Ellis, Wilson. NC
.Amanda S. Englenh. Washington. DC
Debra R. Ernst. West Bloomlield. Ml
Leah S. Fletcher. Ph.D.. Geneseo, NY
Carole J. Forloines. Kenneti Square, PA
.Madeline H. Freeman. Greenville. SC
Kathenne L. Fries. PhD . Atlanta. GA
Jo Ellen F Gilbert. Jackson\ ille. FL
JudithL. Glas, Oakdale. PA
Charies A. Glick. Frederick. MD
Robert P Gruninger. Chapel Hill. NC
Heidi A. Harkins. Ph.D.. Ch.ipel Hill. NC
Janet L. Harrill. Forest Cit\. NC
Margaret P. Herbers. Silver Spring, MD
Marcia W. Herbert. Virginia Beach. V.A
Edna D. Hodges, Washington, NC
Anne C. Huft. Ph.D. and Bruce E Miller. Ph D .
Collegev ille. PA
Diana B. Johannsen. Fredericksburg. \.A
Brigid W. Johnston. Cary. NC
Jane E. Jordan. The Woodlands, T.X
Deborah W. King. Bremerton. WA
Steven W King. Ph.D.. Florence. SC
Susan .A. Klemm. Charlotte, NC
Stephen B. Knisle>. Ph.D.. Birmingham, .AL
Lauree M, Kruyer. Southern Pines. NC
Roben A. Lerch, Ph.D.. Spring Valley. N1'
Scott C. Li\ ingston, Erie. PA
.Amy H. Lumsden, Arlington Heights, IL
Earl E. Macy. West Plains, MO
Melissa Maret, Ph.D.. Vardley. PA
Celia C. McCartv. Alpharetta. GA
William T McGivnev. Ph.D.. Rockledge. PA
Tina W. McKeon. Atlanta. GA
Jona P. Medlin. Raleigh. NC
Beth E. Mileson. Ph.D.. Falls Church. VA
Elzbieta M. Milewska. Saint Charles. IL
Robert E. Moon. Fort Lauderdale. FL
Susan H. Moore. Raleigh. NC
Virginia W, Morton. Houston. T.X
Karl F .Muster. D.D.S. and Carol Richtcr Muster.
Ph.D., Champaign, IL
Lauren B. Noble. Wake Forest, NC
Elizabeth H. Pearsall. Rocky Mount. NC
Dacia N. Pitzer, Cleveland. OH
Dons T. Poole. Ph.D.. Chapel Hill. NC
Gary E. Prillaman. D.D.S. . Mocksville. NC
Tamaia R, Ritchie. Durham. NC
Kristin R. Rogers. Princeton Junction. NJ
Constance Rothermel. Ph.D.. Essex Ealls. \J
James P. Ryan. Memphis. T.N
Rachel J. Sanders. M.S.. Juneau. .AK
Patricia Scronce. Woodbridge. \'.A
J. .Michael Shenill. Danville. CA
Rebecca A. Shirk. Ph.D.. Mahern. PA
Susan S. Skeen, Elon College, NC
Phillip G. Smith, Durham, NC
Jennifer V. Smith. Ph.D.. West Chester, PA
John N. Snouwaert, Ph.D., Chapel Hill, NC
.Anne Steward Solari, Florissant. MO
Sara J. Stit/er. Richmond. \ A
Jean 1.. Stout. Saint Paul. MN
Deborah II Strickland. Apc\. NC
Pamela Perrs Sluhbs. I allbrook. CA
Monroe J. Stutts III. Chapel Hill. NC
Laura I. Tanner. Ph.D.. San I-rancisco. CA
Stuart A, Thompson. Ph.D.. I-:\ans. GA
Louisa B. Thompson. Roswell. G.A
Kllen B. Troutman. Salisbury. NC
Tsong-Tseh I sa\. Ph D . Orange. CA
Cirace S. Tuckei. Dciiison. T.X
Elizabeth F. Via. W insi,,n S.ilciii. NC
Jeanne S. Wagner. Bcisc, 11)
David E. Wain, Wilmington, NC
Chervl H. Whelan. Louisville. KV
Rebekah J. Wilkes. Lillington. NC
Elizabeth C. Wilkinson, 'loungsv ille, NC
Beverly A. Williams. Chapel Hill. NC
Barnaby E. Wra\. Know ille. TN
Albert G. Zimmermann. Ph.D.. Carrboro. NC
F.ACL LT^l
L.irr\ W. .Arnold. M.D.. Snow Camp. NC
Stephen R. .Aylward, Ph.D.. Carrboro. NC
Christopher C. Baker. M.D., Chapel Hill, NC
Nancy P. Barnes. Severn. NC
Stuan O. Bondurant. Jr.. M.D.. Chapel Hill. NC
G.ir> n Bos. MD. Chapel Hill. NC
Watson A, Bowes. .In. M,I),. Chapel Hill. NC
H. Robert Brashear. ,|r.. M.I).. C hapel Hill. NC
Dr. R. Alan and Mrs. Irene Brl(;j;anian.
C hapel Hill. NC
James A. Br\.in II. MD.. Chapel Hill. NC
Joseph A. Butkwalttr. M.D.. Chapel Hill. NC
John B, Buse. M.I),. Ph.D.. Chapel Hill. NC
John 1) Bulls. Jr. MO. Duili.un. \(
Robert C. Cefalo. .M.U.. Chapel Hill, NC
Thomas V. Clancy. M.D.. Wilmington, NC
Richard L. Clark, M.D.. Chapel Hill. NC
William Lord Coleman. M.D.. Chapel Hill. NC
Anna Marie Connolly, M.D.. Chapel Hill. NC
Ernest Craige. M.D.. Chapel Hill. NC
William J. Croimrtic. MD . Ch.ipel Hill. NC
Floyd W. Denny, Jr.. M.D.. Chapel Hill. NC
Robert F Devellis. Ph.D.. Chapel Hill. NC
James F. Donohue. M.D.. C'hapel Hill. NC
William Droegemueller. M.D.. Chapel Hill. NC
Thomas M. Egan. M.D.. Chapel Hill. NC
David E. Eifrig. Sr.. M.D,. Chapel Hill. NC
Paul B. Farel. Ph.D.. Chapel Hill. NC
Newton D, Fischer. M.D.. Chapel Hill. NC
Charles G. Foskey. Chapel Hill, NC
Jeffrey A. Frelinger. Ph.D., Ch.ipel Hill. NC
Eric C. Frey. Ph.D.. Durham. NC
VVilliam E. Garrett. M.D.. Ph.D.. Bahama. NC
l.eon.ird S, Gettcs. M D . Chapel Hill. NC
Robert N. (Jolden. M.I), and
.Shannon C. Kenne>. M,l).. (hapel Hill. NC
Joe W. (irisham. M.U.. Chapel IIIII. NC
John J. Haggerly. Jr.. M.D.. Chapel llill. NC
Joseph W Hall 111. Ml). Duih.mi. NC
William I). Heizer. M.I)., (hapel Hill. N(
Jeffrey 1.. Houpt. M.I)., (hapel Hill. NC
Gregorv 1-, Hulka. Ml). Hillsborough. NC
David G, K.uilm.in. MD . PhD . Chapel Hill. NC
\MIIIam K. Kaufmann, Ph.D.. Durham. NC
.Scott S. Kellev. Ml),. Chapel Hill. NC
Thomas C. Keyseriing. .M.D.. Chapel Hill. NC
Ernest N. Krayhill. M.D.. Chapel Hill. NC
Jan A. Kylstra, M.D.. Chapel Hill. NC
William E. Lassiter. Ml). Chapel Hill. NC
H. R. Lesesne. M.D. Chapel llill. \C
Kcnnelli J 1 evin. M I ). (hapel llill. NC
Jelliev A l.icbeiiiiaii, \I I) . ( li.ipel Hill, NC
( arol N. I.ucas. Ph.D.. (hapel llill. N(
All.in A M.ihhie. M 1). Ch.ipel Hill, \(
Elizabeth S. Mann. M.D.. (hapel llill. N(
Stanlev J. .Martmkoskv. Ph 1) . Chapel Hill. NC
Campbell W .Mc.Mill.in. Ml). Chapel Hill. NC
D.ivul I \leiien. M D. Piiishoio. NC
Anilinnv ,\ Mevei. Ml), Ch.ipel Hill. NC
.Melanie Mintzei. Ml) .Ch.ipel Hill. NC
Don K- Nakavama. Ml). R.ilcpjh. NC
39
Christian E. Newcomer Ph D.. Chapel Hill. NC
Terry L. Noah. M.D., Carrboro. NC
David A. Ontjes. M.D.. Chapel Hill. NC
Anihony N. Passannante. M.D.. Chapel Hill. NC
Edward R. Perl. M.D.. Chapel Hill, AC
David R. Perry. Chapel Hill. NC
Thomas D. Petes. Chapel Hill. NC
Arthur J. Praiige. Jr. M.D.. Chapel Hill, NC
Milton D. Quigless. Jr. M.D.. Raleigh. NC
Kenneth G. Reeb, M.D., Chapel Hill, NC
Desmond K. Runyan.M.D., Chapel Hill. NC
Robert S. Sandler. M.D.. Chapel Hill. NC
James H. Scatliff. M.D.. Chapel Hill. NC
Nicholas J. Shaheen. M.D. and Amy W. Shaheen.
M.D.. Chapel Hill. NC
George F. Sheldon. M.D.. Chapel Hill. NC
Sidney C. Smith. Jr. M.D.. Chapel Hill. NC
Brian C. Stabler, Ph.D., Chapel Hill, NC
Chuck Stone. Chapel Hill. NC
Catherine A. Taylor. M.D.. Chapel Hill. NC
Colin G. Thomas, Jr., M.D., Chapel Hill. NC
Michael D. Topal. Ph.D.. Chapel Hill. NC
Charles M. Van Der Horst. M.D.. Chapel Hill. NC
Judson J. Van Wyk. M.D.. Chapel Hill. NC
.Mahesh A. Varia. M.D.. Chapel Hill. NC
Mark C, Weissler. .\1.D.. Chapel Hill. NC
James R. While. Ph.D., Chapel Hill. VC
Clarence E. Whilefield. Chapel Hill. NC
J, Kenneth Whitt. Ph.D.. Chapel Hill. NC
Frank C. Wilson. M.D., Chapel Hill, NC
Richard V. Wolfenden. Phi).. Chapel Hill, NC
James R. Yankaskas. M.D. and Bonnie C.
Yankaskas Ph.D.. MPH. Chapel Hill. NC
IIOL'SE.STAFF
Kiehard C. .Andrinjja, M.D.. (ireensboro. NC
Ray M. Antley. M.D.. Morganton. NC
William B. Applegate. M.D.. Winston-Salem. NC
James W. Asaph. M.D.. Portland. OR
Thomas .\1. Bashore. M D.. Durham. NC
Stephen N. Becker. M.D,. Libhy. MT
Jeffrey P. Bonize. M.D.. Bryn Mav\r. PA
Thomas A. Brackbill. M.D., Greensboro, NC
Bruce R. Brodie. M.D.. Greensboro, NC
Robert A. Brown, M.D.. Fort Myers. FL
Wallace D. Brown. M.D.. Raleigh. NC
George F. Brumback. M.D.. Greensboro. NC
Edwin L. Bryan. M.D.. Greensboro. NC
Robert V. Buccini. M.D.. Greensboro. NC
Kenneth A. Buddendorff III. M.D.. Mobile. AL
William R. Bullock. M.D.. Charlotte. NC
Allen E. Cato. Jr. M.D.. Durham. NC
G. Raybum Cheely. M.D.. Raleigh. NC
Robert Che\alier. M.D.. Charlottesville. VA
.Arsenio O. Cordoves. M.D.. Miami. FL
Thomas P Cornwall. M.D.. Durham. NC
•Stanley C. Cox HI, M.D., Southern Pines, NC
Barbara A. Crockett. M.D.. Durham. NC
John T Cumes. M.D. and Cheryl A. Viglione.
VI.D. Greensboro. NC
Frederic G. Dalldorf. M.I), and
Joanna S. Dalldorf. M.D., Chapel Hill, NC
Marsha L. Davenport. M.D.. Chapel Hill. NC
A. Joseph D'Ercole. M.D.. Chapel Hill. NC
Wayne R. Detorres. M.D.. Mahwah. NJ
Donald G. Detweiler. M.D.. Raleigh. NC
Douglas R. Dirschl. M.D.. Chapel Hill. NC
Diane M. Duffy. M.D.. Graham. NC
Michael F Durfee. M.D.. Raleigh. NC
Richard Essner. M.D.. Los Angeles. CA
40
Lisa P. Ferran. .M.D.. Durham. .NC
Catherine A. Fomeris. M.D.. Chapel Hill. NC
Charles E. Frederick. M.D.. Greensboro. NC
James C. Garbutt. M.D.. Pittsboro. NC
Larry D. Grubh. MD.. Florence. SC
Todd H. Hansen. .M.D.. Asheville, NC
Frank J. Haraf, M.D., Louisville, TN
Carl R. Hartrampf. Jr. M.D.. Atlanta. GA
Glenn B. Hays. M.D.. North Fort Myers. FL
Xaver F. Hertle. M.D.. Greensboro, NC
Michael A. Hill. M.D.. Durham. NC
Peter J Holland. M.D. and Donna S. Holland.
.\I D. Boca Raton. FL
Robert R. Huntley. M.D. and Joan t . Huntley.
Ph.D., t hapel Hill, Nt
Burton R. Hutto. M.D.. Chapel Hill. NC
Harold N. Jacklin. M.D.. Greensboro. NC
.\li Jarrahi, M.D., VVinston-.Salem, NC
Robert B. Johnson. M.D.. Gary. NC
Thomas L. Johnson. M.D.. Inglewood. CA
J. Jeff Johnson. M.D.. Paducah. KY
F. Douglas Jones. M.D.. Greenville. NC
Raleigh O. Jones. Jr., M.D. and Janine C Jones.
M.D.. Nicholasville. KY
Hisashi Kajikuri. M.D., Monterey, CA
Jeffrey D Kal/. .\1.D . (iicensboio. NC
Moyra E, Kilell. Ml).. Chapel Hill. NC
Jonathan S. Krauss. M.D.. .Augusta. GA
Walter L. Lamar, M.D.. Tulsa, OK
Halcut C. Lawrence HI, \LD., Asheville, NC
Randolph L. Lee. M.D.. Apex. NC
Steven Lipper. M.D.. Chapel Hill. NC
Frank A. Loda. M.D.. Chapel Hill. NC
Dr Jane L. Madison. Chapel Hill. NC
H. Rayinond Madry. Jr. M.D., Raleigh, NC
Bruce T. Malenbauiri, M.D., Durham,, NC
G. Philip Manire, Ph.D., Chapel Hill, NC
Peter J. Massicott. M.D.. Boston. MA
Al.m H. .\l.itsumoto. M.D . Charlottesville. VA
Charles R. McAdams. Jr. M.D., Charlotte. NC
James (.',. MeClure, >LD., Memphis. TN
W. Benson McCutcheon, Jr., \LD., Durham. NC
William T. McKinney. Jr. M.D.. Madison. Wi
Morton Meltzer. M.D.. Cameron. NC
Steven L. Mendelsohn. M.D.. Asheville. NC
James J. Murphy. M.D.. Arden. NC
Mark E. Murphy, M.D.. .Savannah. G.A
Keith A. Nance. M.D.. Raleigh. NC
Charies L. Nance. Jr. M.D.. Wilmington. NC
John L. Nehil, M.D., Louisville. KY
Richard A. Niles. M.D.. Lynchburg. VA
Margaret R. Nusbaum. D.O.. M.PH.. Chapel Hill. NC
John W. Oglesby. M.D.. Nashville. TN
Frederick H. Opper. M.D.. Wilmington. NC
Louis V. Paciho. M.D.. Leeds. MA
Linn H. Parsons. M.D.. Winston-Salem. NC
Joseph F Patterson. Jr. M.D.. Chapel Hill. NC
George H. Pierson. Jr. M.D.. Greensboro. NC
Cedric W. Porter. Jr. M.D.. Asheville. NC
William 1. Proctor. M.D.. Raleigh. NC
Rupa C. Redding-Lallinger. M.D.. Chapel Hill. NC
Hal J. Rollins. Jr. M.D.. Greensboro. NC
Roland E. Schmidt. M.D.. Chapel Hill. NC
Michael S. Schur. M.D.. Satellite Beach. FL
Stephen B. Schuster. M.D., Greensboro. NC
Ronald P Schw.iiv, M D . Raleigh. NC
Stephanie .A. Skolik. M.D.. Huntington. WV
Bryan W. Smith. M.D. and Mary F Smith. M.D..
Chapel Hill. NC
John J. Solic. M.D.. State College. PA
Liang Y. Soo. .M.D. and Dixie L. Soo. NLD..
Chapel Hill. NC
Ernest B. Spangler. Jr.. M.D.. Greensboro, NC
Mary C, Steuterman. M.D.. Greensboro. NC
Thomas NL S«antkovvski, \LD..
Southern Pines, NC
Robert V. Sypher. Jr. M.D.. Greensboro, NC
Dianne W. Trumbull. M.D.. Morgantown. WV
George L. Wallace. Jr. .M.D.. Maninsville. VA
Turin P. Walters, M.D., Huntington, W V
Brent W. Weston. M D.. Durham. NC
Camngton W. White. .M.D.. Durham. NC
Kenneth S. White. M.D.. Wilmington. NC
Robert W. Whitener. M.D.. Greensboro. NC
Frances K. Widmann. M.D.. Chapel Hill. NC
Jeffrey L. Wilson, M.D.. (ilasgow, KY
George T. Wolff. M.D.. Greensboro. NC
Lucas Wong. M.D.. Temple. T\
H. Linton Wray. M.D.. Che\y Chase. ,MD
Peter R. Young, Sr., M.D., (Jreensboro, NC
Nakhleh P. Zarzar, M.D., Raleigh. NC
.Mary E. Zelcnik. .\LD.. Clifton Forge. VA
Thomas .A. Zirker. ML).. Greensboro, NC
Ph.D. GRADL.ATES
Phyllis G. Andrews. Ph.D.. Durham. NC
Linda M. Boland. Ph.D.. Woodbury. MN
Philip Brooks, Ph,D., Bethesda, MD
Ronald K. Charlton. Ph.D.. Jacksoinille. FL
Haroutune Dekirmenjian. Ph.D.. Knowille. TN
Lori Ann Dostal. Ph.D.. Brighton. Ml
David Joel Edwards. Ph.D. and .Mary Hemng
Edwards. M.D.. Pittsburgh. PA
Janet L. Evans. Ph.D.. Stockton. NJ
Charles C. Finley. Ph.D. Chapel Hill. NC
James C. W. Finley. Ph.D.. Cleveland. OH
Beatnce Hughes- Werner. Ph.D.. Chapel Hill, NC
Warren M. Kati, Ph.D., Gurnee, IL
Tec-Ping Lee. Ph.D.. Williamsville. NY
.Michael J. Leiivelt. Ph.D.. Sun Praire. Wi
David P Lewis. Ph.D.. Pearl River. NY
David M. Mottola. Ph,D.. Tampa. FL
Mary Ella M. Pierpont. Ph.D.. Samt Paul. MN
Derek T. Puff. Ph.D.. Somersville. MA
Bonnie B. Punske. Ph.D.. Sandy. UT
.Mariorie S. Read. Ph.D.. Durham. NC
Robert A. Schwartzman. Ph.D.. Gaithershurg. MD
Peter R. Shank. Ph.D.. Rumford. Rl
Charles J. Viviano. Ph.D.. Beacon Falls. CT
Michael D. Waters. Ph.D.. Chapel Hill, NC
President's
Letter
The UNC Legacy
Se\L'ral weeks ago. iii\ wcirkdas was oil tn
a tiHigh start. E\er\()nc was show ing up fur
his appointineni. This led. iiicxorably. tn ni\
falling tiirther and further hehind schedule.
Fifteen minutes should be enough lime lor an
internist tti see a follow-up patient, but that
span is sinipl\ not realistic for some. On this
particular da>. nian\ of m\ challenging
patients were arranged in rapid - a lelalise
term - succession. Most phvsicians. except
perhaps for those in the most rarefied sjiecial-
lies. can relate to m_\ plight.
M\ first three patients that da\ arrived
bearing carefull\ recorded lists of iheir
concerns. Despite the w rillen plea posted in
m\ waiting room — "'No Lists" — m\ pa-
tients gleefulK disregarded m\' sign. Follow-
ing instead the ad\ice in /'rcvciiiicn
maga/ine on how to get the most out ot their
\ isit w ith the doctor. the_\ honed a detailed
outline of the past month's problems. The\
should ha\e read Medical Economics which
brands such patients as "difficult." the type to
be axoided whenexer possible. From either
perspecine. the dreaded Lists guaranteed
that the \ isiis were not going to be neatl) lieil
tip in \5 minutes I
.Also conspiring to keep me off schedule
were several patients with a chief complaint
of "weakness."" Known all too well b\ iii\
colleagues in primary care, weakness ii\als
constipation as the most per\asi\e nialad\
ever lo afflict humankintl. yet the medical
literature is nearlv silent on the subject. I here
are several variants .Among the most com-
mon are: "'Doc. I |usi ain't got no energy."
.And. ".\I\ gel up and go done got up and
went." Occasionally, after ruling out a lew of
ihe common potential underlv ing diagnoses.
1 tlaie lo ascribe some sv mptoms to the aging
process, iiul this can be a less-than-gracelul
lorax into a Ihornx dialogue. "L\e never had
ihis problem before." the patient insists.
"But vou've never been 86 before either. '
I respoiul |ilainly if not bluntly. ,At this
point. I have been in the room lor
2> minutes and mv neallv -cratled otiice
schedule
IS a distant memorv. .Such was mv biisv
Nh>ndav morning back in .Atigust.
What has anv of this to do w ith the L^NC"
Medical .Alunini Assiiciation '.' Perha|is this:
Ihe frustrations of the morning got me thinking
about mv role w ithin the larger medical com-
munitv. .Someone has to he first to wade
through the vast bodv ol patient complainis.
The primary care physician has the responsi
bility to discern, for example, the pedestrian
age-related "weakness" from the "weakness"
of iri>n deficienev. hv polhv ronlism. or
diabetes. Others, such as L'niversilv lacuhv.
may serve bv spending their entire careers on
viral hepatitis or glaucoma, becoming
authorities w ithin a narrow subject area.
Even administrators play a ke\ pari in
providing timelv services in a manner besi
suited to the patient's needs.
So It is too with UNC School of Medicine.
We all occupy an important cog in the
machinery of lop-tlight patient care. Acade-
mics teach, conduct research, and treat rare
diseases. Dean Houpt deals w ith the critical
niacro issues of funding, the Legislature,
phx sical plant needs, and departmental leail-
ership. Sludenls bring energv and enlhusiasm
into the mix.
We alumni contrihule as well. ('omprisei.i
mostly of physicians in private practice, we
prov ide ihe btilk of medical care. Irom our
practices can come a stream of patieiil lefer-
rals. .Also, regular financial support has a
meaningful inipact. and this has been ]iarlic-
ularlv true in recent years. F^ach of us has an
opportunity and an obligation to parlicipale
in the affairs of our alma mater. After all. it
was as students, many vears ago. that we first
became piotid members ol the I'NC" lamilv.
Let us all cherish this sioried legacv. and
responil in kind
CME/Alumni Calendar
Sovemher 1 7, 2000 — The Friday Center. Chapel Hill
Psychuilry Across the Ages; 5lli Annual Update
Sovemher IS, 2000 — The Friday Center. Chapel Hill
17th Annual George C Hani Symposiuni
Estate Planning Notice
Many individuals would like to make a major gift
to the UNC medical center, but cannot commit
current assets for such a purpose. Through a will,
however, anyone can make a more significant gift
than they might ever have thought possible by
designating a specific sum, a percentage, or the
residue of their estate for the benefit of the medical
December I. 2000 — The Friday Center. Chapel Hill
Domestic Violence Conference
Deeeinher 2. 2000 — The Friday Center. Chapel Hill
A Multidisciplinary Approach to Ksophageal Disease
January IS-19. 2001— The Friday Center. Chapel Hill
Challenges in Geriatric Practice: I2lh Annual ("onlerencc
January 31. 2001 - Chapel Hill
Student Research Day 2001
April 27-2S, 2001 - Chapel Hill
Spring Medical Alumni Weekend
For more information about CME courses, contact the OtTicc
ot Continuing Medical Education at (41'*) 9(i2-21 IS or loll
tree through the Consultation Center at (800) 852-6264. To
contact the Alumni Affairs Office, call (919) 962-6786 or
email medical_ahimni(n nied.unc.edu
To provide a bequest, sinq)ly include a paragraph
in your will naming The Medical Foundation of
North Carolina, Inc. as a beneficiary. For example:
"I give, devise and bequeath (the sum of$
or ( % of my estate) or (the residue of
my estate) to The Medical Foundation of North
Carolina, Inc., a 501(C)(3) created to maintain
funds for the UNC medical center with principal
offices located at 880 Airport Road, ChapelHill,
North Carolina."
This language creates an unrestricted bequest for
use by the medical center when and where the need
is greatest, or you may specify that your gift be
used for a particular purpose.
For further information on bequests, contact
Jane McNeer at (919) 966-1201, (800) 962-2543,
orjmcneer@email.unc.edu.
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IVrniil No. 24
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