Medical alumni bulletin [serial]

OF NORTH CAROLINA

Winter 2U01

VMedical Alumni

BULLETIN

School of Medicine, University of North Carolina at Chapel Hill

«

Fetal Surgery at UNC:
Medical Milestone

Dean's
Page

/n November 2000. the UNC Board of
Trustees approved proposals for
tuition increases from the Schools of
Medicine, Business, Law, Pharmacy, and
Dentistry which would he returned to these
professional schools to fund improvements
in their respective educational programs.
These proposals have been endorsed by
UNC-Chapel Hill Chancellor James
Moeser and University System President
Molly Broad. It is expected that if approved
by the University System Board of
Governors in February 2001 , they will be
reviewed by the legislature and would
become effective Fall 2001.

I heard positive responses about the im-
plications of a tuition increase in my discus-
sions with alumni, students and their
families, and with my faculty advisory com-
mittee. I have asked Cheryl McCartney.
MD. Executive Associate Dean for Medical
Fducation and the author of our School's
proposal to summarize it for you here.

&n

L

irjjU^t

.Jeffrey L Hoiipl. MD
Dean. School of Medicine

At $3,220, our medical school's in-state
tuition is second lowest in the country. Pub-
lic peer institutions such as the Universities
of California, Michigan, Washington, Col-
orado and Alabama charge in-state tuitions
ranging from $9,000 to"$ 1 8,000, Our re-
quest to the Board of Governors was to in-
crease in-state tuition to $7,720. phased in
by $ 1 .500 per year over three years. We pro-
ject that even with this increase, our tuition
will still be among the ten lowest tuitions
nationwide. Out-of-state tuition would rise
from the cunent level of $24, 1 1 2 to $27, 1 1 2
similarly phased in over three years by
$1 ,000 per year. In order to protect access to
medical education for all qualified North

Carolina resident applicants. 50 percent of
the revenue from the increase would be ded-
icated to scholarships for in-state students
with demonstrated financial need. We are
committed to ensuring access to under-
represented and disadvantaged students.
Currently enrolled students would not be af-
fected by the tuition hikes.

TTie Accreditation Standards of the Liai-
son Committee on Medical Education
(LCME) recognize that "the substantial cost
of conducting an accredited educational
program leading to the MD degree should
be supported from diverse sources, includ-
ing income from tuition, endowments, earn-
ings by the faculty, parent university, annual
gifts, grants from organizations and individ-
uals, and appropriations from government."

The cost of educating an individual med-
ical student is estimated to be between
$70,000 and $100,000 per year, and is un-
likely to decline. However, we face funding
issues similar to medical schools across the
country that are experiencing reductions in
key sources of support such as reimburse-
ment for faculty's clinical work. Although
there is national concern about rising tu-
itions and the resulting rise in indebtedness
of graduating medical students, studies
show that physicians" eventual earning
power has been sufficient to repay their edu-
cational debts early in their professional ca-
reers. Our final decision to propose a tuifion
increase resulted from our motivation to
sustain excellence in our educational pro-
gram. New developments in science, soci-
etal needs, and physician practice patterns
demand our investment in curriculum de-
velopment and teaching innovations.

By many measures, the UNC School of
Medicine is a national leader. Our 1999 re-
search funding from the National Institutes
of Health ranked 15th overall and 5th
among public medical schools. In April
2000. a U.S. News and World Report survey
ranked UNC 23rd among schools of medi-
cine. 8th in primary care. Our family medi-

cine program was 2nd in the nation and our
rural medicine program ranked 4th.

The 1997 LCME site surveyors recog^
nized the "efforts of a dedicated and talent-
ed administrative staff and the commitment
of a faculty dedicated to teaching." Howev-
er, they criticized our "traditional curricu-
lum" which remains "departmentally based,
lecture intensive, and limited in time for ac-
tive learning in the first two years." Among
the remedies they suggested were increased
emphasis on small group problem-solving
learning techniques and expansion of the
use of electronic educational technology.
These improvements would require more
faculty time and faculty development than
the current curriculum as well as invest-
ments in redesign of teaching spaces, and
new and upgraded scientific equipment and
technology.

With the recent approval of the $3.1 bil-
lion bond issue to fund improvements in the
16-campus University of North Carolina
system, the School of Medicine can now af-
ford to plan major renovations of our teach-
ing spaces, including Berryhill Hall which
has not been substantially changed in 30
years. The School of Medicine portion of
the Carolina First Campaign has earmarked
$50 million in private gifts for technology
infrastructure, faculty development, student
support, professorships, and scholarships.

Until recently, tuition paid by students in
the UNC system was sent to the state's gen-
eral fund, but the new tuition revenues will
be returned directly to our students in im-
provements to their educational experience.

Medical Alumni
Association Officers

President

Paul E. Viser. MD "84
Clinton

President-Elect

Thomas J. Koontz. MD '66
Winslon-Salem

Vice President

Ray M. Hayworth. MD "62
KiKKwille. Tn

Secretary

John M. Herion. MD "83
Wilniini^ton

Treasurer

Wilham M. Hemdon. Jr.. MD '81
Charlotte

Editorial Staff

John W, Stokes

Vice President, Public Affairs

& Marketing

Debra Pierce
Editor

Eileen Barton. Laura Ertel.
Bemadettc Gillis. Leslie H. Lang.
Katie Macdonald. Karen Stinneford.
GinL'er Tra\is
Contributing Writers

Dan Crawford (pgs. 8. 2.*))
Ja\ Magnuin (pgs. 2. 6. 7. 14)
Photoi;raphers

The Mnlii III Alumni Hiilliiiii is published four limes
annualK hy the fNC-Chapcl Hill Medical Alumni
AsMKiJIion. Chapel Hill. NC 27514 Postage is paid
by the nonprofn association through L' S Postal
Permit No. 24 Address correspondence to the editor.
Office of Medical Center Public Affairs. Schix)l of
Medicine. CB#7«K).Lnivcrsitv of Nonh Carolina
Chapel Hill. NC27.S 14

Medical Alumni

BULLETIN

School of Medicine, University of North Carolina at Chapel Hill

Contents

Features

Hubbard Program Fosters Collaboration Among Students 2

Mending Small Hearts 4

On f/Ston.UNC Takes On Delicate. Risky Challenges of Fetal Surgery 6

School Launches Medical Alumni Endowment Campaign 8

Highlights ofFall 2000 Medical Alumni Weekend 1(1

Faculty Profile: Travis Meredith, MD's Vision For Ophthalmology is 20/20 14

Premature Deli\ery Led Doctor to Write Book on Preemies" tor Parents 20

Merrimon and Whitehead Lectures 2 1

/\/((/whPw/;7<'.- Clarence Miller. MD "44 22

Honor Roll Corrections 24

A Student Proves It's Never Too Late 2(i

Departments

Deans Page Inside Front Co\cr

Faculty Notes 12

News Briefs Id

Research Briets \S

Development Notes 2.'i

.Mumni Notes 27

President's Letter Inside BackC'o\ci

CMF7AlLimni Calendar Back Cover

On the Cover: Surjieons at L'NC Hospitals pcrtomi North Carolina's llrsl in ulcro surycPi on .i
k-liis. Nancy Cheschcir. MD. left center, leads ihestirtiical leani PluiUili\.la\ Mansion

Hubbard Program Fosters

By Katie Macdonald

In an ideal health care system, all care-
givers would work together for the good
of the patient. No one job would be con-
sidered more important or more re-
spected than the next, and each individual,
whether they are a doctor, nurse, social work-
er or pharmacist, would understand the value
of the other's contribution to the enormous
task of providing health care to sick people.

Such were the intentions of Elizabeth T.
and William N. Hubbard. Jr.. MD. who in the
mid-80"s stiirted a fund administered by The
Medical Foundation of North Carolina. Inc..
in support of programs at UNC geared to-
ward research, study and the demonstration
of collaborative clinical practice by health-
related professions.

In a letter he wrote in September 1986 to
then Dean of the School of Medicine. Stuart
Bondurant. MD. Hubbard stated his inten-
tions and the conditions for the fund.

■"Because a common concern for the well-
being of the person served is the most impor-
tant unifying commitment of the several
health-related professions, collaboration in
clinical practice should have patient benefit
as its principal organizing consideration," he
wrote. "The unique integrity of the individual
person being served and the dynamic quality
of the varieties of opportunities open to each
health professional for contributing to im-
proved human well-being suggest the essen-
tiality of collaboration among each of the
involved health professionals in both episod-
ic and extended care."

Hubbard, fornier dean of the University of
Michigan School of Medicine, knows all too
well the reality of traditional health care,
where hierarchy, myths, stereotypes and mis-
communication sometime hinder the deliv-
ery of optimum patient care. The agendas of
physicians and nurses clash at times: physi-
cal and occupational therapists are often not
given the respect for their jobs they deserve:
pharmacists are not expected to interact with

CUissimitc's and inslruclors gather before a patient visit. Standing from left are: Malaz
Boiistani. MD, geriatric fellow: Greg Simpson. Florence Solty-s. MSW. Sitting from left
are: Melinda Snider. Cherie Rosemond. MS. PT. Nancy Green-Knepper Contina Bell.

patients and social workers can be left out of
the loop entirely. If only each profession un-
derstood the indispensable role all health-
related fields play in patient care. Would it be
too much to ask for everyone involved to
know the roles of each health care profes-
sion, how they interact and how to utilize
them to help the patient?

Cherie Rosemond. MS. PT and Florence
Soltys. MSW of the Program on Aging, have
created a project, funded by Hubbard, that
embodies Hubbard's original intentions for
collaborative practice among health-related
professions. Through a special, faculty-
initiated selection process, five students, a
resident from the department of family
medicine, a pharmacist, a social worker, an
occupational therapist and a nurse pratiction-
er join as members of a team devoted to

caring for frail older adults.

"We concentrate on geriatrics because the
problems for the elderly are often complex
and require the expertise of many disciplines
to be adequately addressed." said Rosemond,
who has served on the faculty of UNC's
physical therapy program for the last eight
years.

Focusing on the elderly also fulfills anoth-
er of Hubbard's intentions for the fund,
which was to allocate money to educational
projects that sought to help the poor, the very
young or the elderly. "The people in these
groups are the most likely to have measur-
able benefits from collaborative practice,"
Hubbard wrote in his letter to Bondurant.

The Program on Aging, under the leader-
ship of Jan Busby-Whitehead. MD, has re-
ceived funding from the Hubbard family

Collaboration Among Students

since 1997 for their project, known as the
Huhbard Program. So far the project has
managed to secure funds by conscientiously
follow ing Hubbard's specific guidelines,
which include creating w ell-designed assess-
ment and outcome measures that can defini-
tively show the project's effectiveness. "We
have designed a home call service that ad-
dresses the concerns of the patient, their fam-
ily and the referring provider." said
Rosemond.

The team also fulfills another of Hub-
bard's intentions, which was to share the re-
sponsibility of being a team leader among the
group of students. When they meet one after-
noon-a-w eek at Carol Woods, a retirement
community in Chapel Hill, one of the team
members, through a weekly rotation process.
presents the patient the group plans to \ isit
that day. The team leader for the w eek also is
responsible for follow-up communication
with the patient. To Hubbard's insistence, the
project does not function as a simple hierar-
chy, but is. as he stated, "capable of shifting
ihe identity of the lead clinician so that coor-
dination of efforts by the health professionals
is preser\ed through shared information and
agreed protocols of individual practitioner
responsibility."

Often the team's discussions about pa-
tients they have seen, or the patient they pre-
sent that day. break off into frustrations about
the health care system and social security's
impact on the elderly.

"The way the system is now is cra/.y."
-Soltys commented at one of the recent meet-
ings. "It maximizes isolation for Ihe elderly."

Because many of their patients are isolated
trom the community and have an immediate
need of medical care, the team of seven
travels as far as Siler City and F^ittsboro to
treat patients.

"Wc get to spend more lime on one palicnl
and really focus on their medical and social
problems." said team member Greg Simp-
son, who is studying to be a family nurse
practioner. "I love how the team comes to-
gether to be the patient's adviKate."

Pharmacy student Nancy Green- Knepper
agreed. "We take more into account when we
consider the patient's circumstances. We
look at their social situation and life history
and because we are a team of different med-
ical professions, we get different perspec-
tives that are helpful to share."

At one meeting, the team review s the med-
ical and social history of Gerry Gorley. an 89-
year-old woman liv ing alone at Carol Woods.
Gorley has never been manied. but owns a
small dog. Tammy, whom she adores but
who also is becoming harder to take care of
as Gorley's physical limitations increase.

She has had back trouble most of her life
and had surgery when she was in her early
twenties that fused six vertebrae. Her legs
ache and she is slowly losing the strength and
energy that once epitomized her active life.
As a young woman, Gorley loved to go
camping and horseback riding. She also
moved around a lot. living in places such as
Sante Fe. Kansas. Denver, and Chicago.

Gorley moved to Carol Woods in March
1992 and has no living relatives. She gave up
a home with a yard for her one-bedroom
apartment in the retirement community, but
has a nice view of the trees and woods that
color the landscape during the changing sea-
sons.

"God's gift of life can be seen outside my
window and it reminds me that it is a blessing
just to be here on earth." Gorley remarked to
the team, gathered on couches, chairs and the
floor to talk to her and listen to her story. On a
typical day. Gorley wakes up at 8 a.m.. medi-
tates and counts her blessings that she is still
alive. Herdavs are usuallv tilled with writing
letters, calling friends and taking lime lo
view the outdoors.

The team spends most of their lime with
Gorley listening to her daily routines and the
stories of her young adulthood. Later, during
their meeting, the team will assess Gorley's
health and afterward devise a written follow-
up plan, including recommendations from
each (cam member on everything from med-
ication to social activ ities. Both Gorlev antl

her doctor will review the team's adv ice.
which is designed to improve the patient's
health both physically and emotionally.

"The interaction of the group really
strengthens your ow n discipline." said Conti-
na Bell, a social work student. "When I'm
out practicing for real. I won't have the team
with me. Therefore, this project is a good op-
portunity to learn about other medical fields
and how we can work together for the good
of the patient."

Knepper added. "Now when 1 see a pa-
tient, I think, what would a physical therapist
do? A social worker? I've been spoiled by
this group and w hen 1 go home from our
meetings, I think, w hat is practice going to be
like w ithoul Cherie or Florence and the team
members'"

For the last three years, Rosemond and
Soltys have given students the opportunitv' to
know and understand the responsibilities of
other healthcare professions. They have also
instilled in their students the v ital importance
of geriatric medicine lo our cver-grow ing
aging society.

"When your taking care of a patient by
yourself, you take for granted w hat needs to
be done and w hat you need lo know." said
Simpson. "Bui this experience has been greal
in debunking the siereoly pes I may have had
about others in health care, and it's helped me
respect other health care professions." D

Mending

By Eileen Barton

Most people think of it as an
"adult illness," yet heart disease
strikes one out of 100 Ameri-
can children born every year.
Other than asthma, it affects more children
than any other childhood disease and holds a
dubious fust place in birth defects.

At the North Carolina Children's Heart
Center in Chapel Hill, multiple health care
specialists collaborate to care for children
with heart disease. Pediatric cardiology, pe-
diatric cardiothoracic surgery, pediatric car-
diac anesthesia, pediatric critical care
medicine and social services interact dynam-
ically to provide a seamless spectmm of care
for children with heart disease and their
families.

Heart disease touched the Stephen
Buchanon family of Greensboro when doc-
tors diagnosed a condition known as Tetrolo-
gy of Fallot in their three-day-old son,
Logan. Babies with this condition have pul-
monary artery, heart valve and chamber de-
fects that reduce oxygenation of the blood.
Most babies with this defect have open-heart
surgery before they enter school. Logan was
four-and-a-half months old when he came to
UNC for surgery.

Logan's mother, Allison, recalls her fami-
ly's experiences leading up to, and since, that
unforgettable day. As she described the jour-
ney from diagnosis through rehabilitation,
Logan's gleeful sounds were clearly audible
in the background. "He's almost too healthy!
He's a wild man!" she exclaimed.

Besides the events surrounding Logan's
condition, Mrs. Buchanon was stmck by the
tremendous teamwork of everyone involved.
"I am so impressed with the way in which
various doctors from different areas came to-
gether for him," she said. "They worked side-
by-side to make him well; they played a huge
role in his treatment."

One UNC physician who helps ensure a
focus on patient care is G. William "Bill"
Henry, MD. professor of pediatrics and chief
of pediatric cardiology. As director of the
N.C. Children's Heart Center, Henry brings

G. William ■■Bill" Heniy. MD. professor of
pediatrics and chief of pediatric cardiology

together the diverse medical, surgical and
nursing speciahies necessary to offer inte-
grated— yet individualized — patient care.
"When we say "children's heart disease.'
we are talking about specialized care that en-
compasses many different activities occur-
ring in diverse locations," Henry said.
"Things are happening concurrently inside
and outside the actual hospital setting. An
anesthesiologist and surgeon are busy in the
operating room, cardiologists are busy in the
cardiac catheterization laboratory, critical
care physicians are in the intensive care unit
and cardiologists are staffing a variety of out-
patient clinics. We are talking about different
disciplines contributing in an integrated way
to the welfare of the child. I have the pleasure
to work with superb physicians who are sim-
ply the best at what they do."

And it's not all happening in Chapel Hill.
Henry also presides over a network of five
satellite pediatric cardiology clinics in Wilm-
ington, Raleigh, Greensboro. Fayetteville
and Ruthert'ordton. "The heart center reaches
out to the community." he said. "We go out
where there is a need, providing specialty
care locally."

The specialty clinics are conveniently situ-
ated throughout the state so that they are ac-
cessible to families of children with heart

disease. If the family's doctor examines the
child and recommends a cardiac specialist,
he can refer the child to a clinic within a rea-
sonable proximity. At UNC. diagnostic func-
tions are performed including assessment by
history and physical examination, electrocar-
diography, and cross section/color flow
echocardiography, a diagnostic test in which
a probe is placed on the chest while ultra*
sound waves detect the condition of the pa-
tient's heart.

A remote telemedicine network connect-
ing newborn intensive care units throughout
the state allows this sophisticated procedure
to be interpreted by pediatric cardiologists in
Chapel Hill using a videoconferencing link
without having to move the child.

If a child requires more sophisticated care,
he comes to UNC, where both outpatient and
inpatient care is provided. Exercise testing,
transesophageal echocardiography, cardiac
magnetic resonance imaging, cardiac cine-
tomography, cardiac catheterization and a
variety of therapeutic interventions are
among the specialized services provided.

The N.C. Children's Heart Center encom-
passes a myriad of disparate but equally
important specialties. Annually, more than
5,000 patients are treated, about 200 opera-
tions, 200 cardiac catheterizations and more
than 5,000 echocardiograms are pert'ormed.

"This center is one excellent example of
the extraordinary services we are able to pro-
vide to children," says Dan Lehman, admin-
istrative director for cardiovascular and
wellness services.

Lehman leads a management team re-
sponsible for developing cardiovascular ser-
vice lines for the heart center. Currently, he is
involved in plans to house pediatric diagnos-
tic functions including treadmill tests,
echocardiograms and EKGs in the new N.C.
Children's Hospital which opens later
this year.

Since patients and their families continual-
ly require these diagnostic and support ser-
vices as part of their treatment, "having the
equipment and a team of counselors and clin-
icians together will lend tremendous support
to families," he said. "They will have one

Small Hearts

place, with which they can identity and re-
late. The N.C. Children's Hospital will allow
our heart team to expand our highK -special-
ized care to ensure the children of this state
recei\e the highest standard of care available
anywhere."

Surgery is another vital part of the pedi-
atric heart care package. What distinguishes
the N.C. Children's Heart Center from the
rest, explains Michael Mill, MD, director of
the cardiac transplant program, is that "xirtu-
alls ans thing being done today in pediatric
heart care can he perfonned here. Because of
the considerable advances that ha\e been
made in the field, families nou face very
promising prognoses. We help people accept
that their child has heart disease, and that
there is a way out of this. Yes, the prospect of
surgery can be frightening, but it is often a
critical step along the pathway to health."

Another valued contributor to UNC's
commitment to healthy young hearts is a per-
son described b) most parents as a "gift."
Her name is Maggie Morris, and the extraor-
dinar\ sen ice she prt)\ ides as coordinator of
the Carolina Parent Network is long remem-
bered by the families she meets.

"We are a pre-and post-operative parent
support, information and education net-
work." she explained. "When a child is diag-
nosed w ith a heart problem. 1 call that family,
discuss w ith them their particular situation
and tell them how we might be able to help. I
offer to put them in touch w ith another fami-
l\ that has been through the same experience
or one very similar " Because the network
shares infonnation about heart issues, fami-
lies feel empowered to make inloniicd choic-
es. Moms has a database of more than I .()(X)
lamilies. When she learns about a new pa-
tient, she can zero in on specific geographic
areas to tlnd another family in a similar situa-
tion. The network offers practical education,
comtort and an opportunity for families to
meet other like themselves.

Susan Stringer of Jamestown, NC. has
been so touched that she now volunteers at
the Children's Heart Cenler. The mother ot
four children ages from 4 to 22. Stringer ex-
perienced first hand the trauma of heart ill-

Logan Buclumou. a licaltliy pariciu of
North Carolina Children ',v Heart Center

hive -year-old. Moiin a Sirini;er also
receives treatment at the North Carolina
Children '.v Heart Cenier

ness when her youngest daughter, Monica.
was diagnosed with coarctation, or narrow-
ing, ot the aorta.

"1 knew something was wrong when she
had the snitfles al six weeks of age." Stringer
said. "1 was nursing her and she was so pro-
tected, too young to ha\e these symptoms.

Her weight dropped, and she was dehydrat-
ed. We took her to the hospital and they dis-
co\ eicd she had RSV. a \ inis. I subsequently
learned thai if an infant is hospitalized with
this, there is usually an underlying heart or
lung problem. Her lungs were so wet the
doctors could not pick up sounds from her
heart."

Finally. Stringer took her daughter to
Henry at UNC, where the baby unden\ ent an
echocardiogram that detected serious heart
problems. She w as scheduled for surgery at
fixe months of age. weighing Just 1 2 pounds.

"Handing my baby o\ er to the pediatric
anesthesiologist was the toughest thing I've
e\er done." Stringer said. "She was in pedi-
atric intensi\e care for 10 days. We had to
make lots of phone calls and ask for help
from family and friends, since our other chil-
dren were at home. Following the surgery,
we had to keep her isolated. But evervone on
UNC Hospitals' staff was outstanding, and
ever since the operation we'\e had excellent
reports."

Monica Stringer is now fixe years old.
Perhaps the finest testimon) to the N.C. Chil-
dren's Heart Cenler excellence is captured by
her words every lime she travels to the clinic
for her twice yearlv checkup: "They fixed
my heart." D

UNC Takes On the Delicate,

P

By Karen Stinneford

hysicians at UNC Hospitals surgi-
cally treated an unborn baby for a
debilitating birth defect called
spina bifida in December
In doing so. the hospital affiliated with the
University of North Carolina at Chapel Hill
School of Medicine becomes only the fourth
in the countiy to offer the highly specialized
surgery to expectant parents whose unborn
babies have been diagnosed as having spina
bifida. Others are The Children's Hospital of
Philadelphia, the University of California at
San Francisco Medical Center and Vander-
bilt University Medical Center in Nashville,
Tenn.

The mother, who is not being identified,
and her unborn baby are doing well. UNC
physicians hope to deliver her baby by Cae-
sarean section in March.

Spina bifida is the most common neuro-
logical defect in the United States, occurring
once in every 1.500 births. North Carolina
has the unfortunate distinction of leading the
nation in the incidence of spina bifida - one
of every 500 North Carolina babies is born
with it.

Babies with spina bifida have an opening
in their spine. Although it is not a fatal disor-
der, spina bifida can be severely debilitating.
Children can have lower limb weakness or
paralysis, sensory loss, learning disabilities
and bladder or bowel incontinence.

Most of the babies also experience some-
thing called a Chiari II malfonnation. which
occurs when the hindbrain "slips" backward
in the skull onto the spinal column. This
makes them prone to hydrocephalus - a
pooling of spinal tluid on the brain - for
which doctors must surgically implant a
"shunt" to drain the excess fluid. Shunts are
notorious for failing or becoming infected.

Currently, physicians operate on babies
with spina bifida shortly after birth to close
the opening in their spine. By then, the dam-

Ditriiiii the
uterus.

i'n: pinsicians open the mother's abdomen and partially remove her

^sky Challenges of Fetal Surgery

age from the Chiari II malformation has been
done, said Nancy Chescheir. MD. professor
of obstetrics and gynecology, director of the
Fetal Therapy and Surgery Program and
head of the surgical team.

"There's a good deal of evidence that
shows that if we operate on spina bifida ba-
bies midw ay through the pregnancy — rather
than w aiting for them to be bom — we can
halt or e\ en reverse the damage caused by the
Chiari II malformation."" Chescheir said.

"About half the babies operated on in
utero won't need a shunt, as compared to
some 80 to 90 percent of all babies bom with
spina bifida. That's good news for
the babies, and good news for their
parents."" she said during a news
conference.

During the surgery, physicians open the
mother's abdomen and partially remove her
uterus. They remove the amniotic fluid that
cushions the unborn baby in the utems. They
turn the fetus to expose the opening on its
spinal cord and sew the opening shut. Physi-

UNC Hospitals

is one of

four in the

U.S. offering

this highly

specialized

surgery.

cians stiich the utems shut, replace the amni-
otic lluid. return the uterus to the abdomen
and stitch it shut. The entire operation takes
about two hours.

.Spina bifida is among a group of birth lic-

Tiiu Weinei: MD. pcilianic siii\;e<in. wdtchc.
.siirgety in an adjacent opcratini^ room.

fects called neural tube defects that affect the
backbone and brain. Every fetus's spine is
open when it first forms, but that opening
normally closes around the 29lh day after
conception. In spina bifida, however, the
opening never closes completely.

Scientists aren't sure exactly what causes
spina bifida, although they believe a combi-
nation of genetic and environmental factors
are to blame.

Researchers do know, however, that folic
acid taken before conception dramatically
decreases the risk of neural tube defects like
spina bifida. Because many pregnancies are
unplanned, the federal government recom-
mends that all women of child-bearing age
— regardless of w hether they w ant to be-
come pregnant — consume 0.4 milligrams of
folate acid daily through food or \ ilamin siiji-
plcmenis.

The mother is being carcil lor through the
UNC Center for Maternal and Infant Health,
a collaboralive inilialive of the School of

(/ monitor us colleagues peiform the

Medicine's departments of obstetrics and gy-
necology and pediatrics, and the North Car-
olina Women's and Children's hospitals.
(The new hospitals open later this year.) The
center is dedicated to improv ing the health of
all women and infants in the state through
clinical services, outreach programs, educa-
tion and research.

In caring for its patients, the center assem-
bles a wide range of medical expertise in one
location and then carefully directs the deliv-
ery of treatment to ensure the best care possi-
ble. By offering coordinated services for
pregnant women and their infants with seri-
ous medical condifions. the center provides
diagnosis, consultation and expert care to
avoid or lessen the severitv of hiilli complica-
tions.

The first center of its kind in the country,
the UNC Center for Maternal and Infant
Health is creating a model svslcm of perina-
tal care. D

School Launches Medical

$7 Million Goal Earmarked fo)

By Laura Ertel

With the cost of a medical edu-
cation rising, the UNC School
of Medicine is looking to its
alumni to help sustain its repu-
tation as one of the top medical schools in the
nation.

In Febniary 2000. the School launched the
Medical Alumni Endowment Campaign to
raise at least $7 million to provide perpetual
support for scholarships, professorships, and
research. Already, alumni have committed
nearly $2 million toward the two-year cam-
paign.

Based on the growing tide of alumni giv-
ing over the past decade. Jane McNeer, Vice
President of The Medical Foundation of
North Carolina, Inc., is confident that the
School is looking to the right people for sup-
port. "Today, only 17 percent of the School's
nearly half-billion dollar budget comes from
the State - down from 21 percent in 1990,"
McNeer explains.

"As State appropriations have lagged, our
alumni have really stepped up. Since 1989,
alumni giving has jumped from just 9 percent
participation in 1989 to 49 percent today,
with almost $2.5 million last fiscal year in
gifts to the Loyalty Fund, endowment and
other programs. That level of participation ri-
vals any public or private medical school in
the countiy."

Campaign co-chair George Cox, MD
"66, believes his fellow alumni are up to this
newest challenge. "Everyone I've talked to
understands the importance of maintaining
our level of annual giving while building the
School of Medicine's endowment," he says.
As alumni, the value of our medical degrees
is in direct proportion to the School's reputa-
tion today. This is a wondeiful opportunity to
give back to an institution that has given us so
much while also increasing the value of our
degrees." This is also an opportunity to name
an endowment in perpetuity.

Schoors Endowment Small
Compared to Peers

Today's UNC School of Medicine ranks

Geori>e Co.\. MD '66. center, am! the Campaign Steering Committee discuss the work ahead.

among the top five public medical schools in
the nation and among the top 25 overall. The
School has earned its reputation for excel-
lence in spite of an endowment which, at
$128 million, pales in comparison to the en-
dowments of its peer institutions. Among the
five public medical schools in the top 25 na-
tionally. UCLA has an endowment of $603
million; Michigan, $302 million; Washing-
ton, $256 million and UC-San Francisco,
$203 million. The private Duke School of
Medicine benefits from an endowment of
$581 million.

Because endowment gifts are invested and
only a portion of the earnings spent each
year, the principal continues to grow over
time and provides vital, guaranteed support
for the School in perpetuity. It is this certain-
ty that makes a strong endowment so impor-
tant for any academic institution. Donors can
name the fund for themselves or for someone
they wish to honor.

"Endowment is a stabilizer during eco-
nomic down times, a cushion against increas-
ing program costs, and a measure of certainty

that allows us to plan for the future," says
School of Medicine Dean Jeffery L. Houpt,
MD. "Like all medical schools, we realize
that our alumni are the ones who best
understand and appreciate the value of
our institution, so we rely on their support
to help us stay at the forefront of medical
education."

Medical Education, Ttiition Costs
Rising

The money raised through the Medical
Alumni Endowment Campaign will go to-
ward several priorities that are currently
funded through annual contributions to the
Loyalty Fund. But with rising education ex-
penses — the actual cost of a medical educa-
tion now stands at about $100,000 per
student each year — neither source of fund-
ing can suffice on its own.

The N.C. General Assembly has approved
a tuition increase that will take the medical
school's tuition from $3,300 (the lowest tu-

Alumni Endowment Campaign

kholarships, Teaching, and Research

ition of all 125 medical schools in the coun-
try ) to S8.000 per year over the next three
years. Even with this increase. UNC will still
be the seventh or eighth least expensive med-
ical school in the nation, a bargain when
compared to pri\ate schools where annual
tuition tops $30,000.

The tuition increase makes building the
School's endow ment even more pressing.
since scholarships w ill need to cover signifi-
cantly more tuition for each student. Co-
chair Ted Kemer. MD "85. notes that, "with
tuition more than doubling, annual unre-
stricted gifts to the Loyalty Fund which
funds 51 full-tuition scholarships simply
cannot keep pace. Endowment, supplement-
ed by Loyalty Fund gifts, will pro\ ide much
of the steady, ongoing support we need to
bring outstanding students to UNC. These
scholarships are particularly gratifying be-
cause they mean so much to students, and the
generosity of today's alumni starts a cycle of
gi\ ing that can benefit our medical students
for generations to come."

Campaign Goals

The Medical Alumni Endow ment Cam-
paign, which runs through Spring 2002, is
part of the Uni\ersity's SI. 5 billion Carolina
First Campaign. The S7 million campaign
seeks to raise:

Scholarships/Merit Awards

\ minimum of S5.6 million to endow 31
lull in-stale tuition scholarships to include
both need-based and merit av^ards. one-year
and four-) ear scholarships and aw ards for al-
lied health sciences students and for medical
students interested in primary care. For many
students, these awards make the difference in
their decision to enroll at UNC - or in their
ability to attend medical school at all.
Already. 12 alumni have committed
to establish scholarships through this
campaign.

Campaign Goals at a Glance

Minimum Total Goal

S5 .600.000

Minimum Naming Gift
Cash Planned Gift

$100,000 SI 50.000

5 1 Endow ed Scholarships/

Merit Aw ards

Four Teaching Professorships $1,000,000 $250,(K)() $300,000

Four Research Seed Grants $ 400.000

Total Campaign Goal $7,000,000

Raised to Date $1,950,000

$100,0(X) $150.(K)0

Meet the Medical Alumni Endowment
Campaign Steering Committee

Co-Chairs

George Cox "66
Ted Kemer "85

Atlanta. GA
Lewisville. NC

--

Wallace Baird '69
Dick Boyd "56
Dan Crocker -70
FredDalldoriUS

Greensboro. NC
Statesville.NC
Rocky Mount, NC
Chapel Hill, NC

Phil Deaton "66
John Foust "55
Ra> Hay worth "62
Bob Sevier '66

Greensboro. NC
Charlotte. NC
Knoxville. TN
Greensboro. NC

ing medical faculty in an increasingly com-
petiti\e market. Endowed awards alle\ iate
some of the financial pressure on faculty to
see patients, allow ing these excellent teach-
ers to focus more of their attention on the
classroom.

Research Seed Grants

At least S4( )().()()() total to endow four re-
search seed grants of $2.(KX) to $5.0(K) annu-
ally in support of promising research by
students, house staff, and facultv members.

Teaching Profes.s(»rships The Medical Alumni Endow ment Cam-

A minimum of $1 million total for four paign accepts current gifts of cash, securities.

three-year teaching professorships that will and real estate as well as planned gifts in the

help the School recruit and retain oiitsland- torni ot bequcsis. charitable remainder

trusts, and several olhcr options. Gifts ol tax-
deferred retirement plans and life insurance
are also encouraged. .'Ml gifts and pledges re-
ceived by June 2006 will count both toward
this campaign and the Carolina First Cam-
paign and will receive special recognition.
During this campaign, the School will con-
tinue to rely on annual gifts to the Loyalty
Fund vital support for student programs,
scholarships and professorships, publica-
tions, and alumni events.

I'or more information about the Medical
,\lumni FJHlowinent Campaign or to make a
gill or pledge, call Jane .McNcer or Mary
Ollila at The Medical F-\)undation of North
Carolina, Inc. at (800) 4f)2-2.543. D

Highlights of Fall 2000

FY 2000-01 Medical Alumni Liivaln Fiiinl Scholars and Endowment Grant recipients are recognized at Fall Medical
Alidniii weekend

Left to right. Dean Jeffrey L. Hoiipt. MD. Clarence M.
Miller Jr.. MD '44 and J. Charles Jennette. MD '73.
Chair and Brinkhoiis Professor of Pathology

Thomas Koontz. MD '66 (President-Elect M.AA. Win.'^ion-.'ialem) and wife Lyime: Paul
Viser. MD '84 {President MAA. Clinton}

From right rear: Jane M. McNeeriV.P Medical Foundation). Dean Jeffrcx L Houpt. MD. Corinne Hoiipl. George
Co.x. MD 66 (Atlanta). Vincent Bynum. Milele Kudumu (MS2). H. Wallace Baird. MD '69 (Greensboro). Betty Ann
Miller Clarence M. Miller. Jr.. MD '44 (Sewickley PA). Maiy Susan Fnlghum. MD '71 (Raleigh).

10

Medical Alumni Weekend

John W. Foiist. MD '55 iNalidinil Chair oj ihf Liyahx Fund. Chailoin) cuhlirsscs the lari^csr c\rr Fall Medical Aliimiu wcckciul hainiiul.

Some oj the Lii\allt Fund A\s<i( uiles ullcndiiii; the Inuiquct include: Ixft lo rif;lil hack ran : Faul I:. \ /sc/;
MD ■H4 iCIinton). Frederic G. Dalldorf. Ml) IIS (Chapel llilll. Carl S. Fhti>in. MD '62 (Win.slon-Saleml.
Robert S. Jones. MD '54 iShelhxI. John M. Herion. .Ml) 'SJ (Wilminnlonl

U'fl to ri^hlfronl nm: R. Glenn Butler. BSMTC 76 (Escimdido. CA). Ray M. Hayworth. Ml) '62 I Know die
TiW). Mary Susan Fulahum. MD '71 (Raleigh). William E. Easterling. Jr.. MD '5(i (Chapel Hill)

Mark Your Calendar!

Spring Medical
Alumni Weekend
April 27-29. 2001

A hrochiirc ciitd

specific reunion

information will he

mailed in Fehriiary:

lor updated

infirmation visit

www.med.iiiK .cdu/iitiimni

Faculty
Notes

Stuart Bondurant, MD. professor of medi-
cine and dean emeritus
of the School of Medi-
cine, was recognized by
the Institute of Medicine
with the David Hall
Medal. The organization
cited Bondurant for
'•particularly distin- Bondurant
guished leadership" as chair of a study com-
mittee and showing "exemplary commitment
substantially above and beyond the usual ex-
pectations."

Donald T. Forman, MD, professor of
pathology and laboratory medicine, received a
special recognition award from the American
Chemical Society. The award recognizes peo-
ple who have worked throughout their profes-
sional careers to advance the society's
professional objectives. Forman has served as
a member of the society's Committee on Clin-
ical Chemistry since 1990 and its chair since
1998. At the society's annual meeting, he or-
ganized and moderated a symposium on "Ani-
mal Models of Gene Diagnosis and Therapy."
Forman's committee promotes the practice
and profession of clinical chemistry, improve
educational programs, boost research and
serve both cheinists and the public.

Adam Goldstein, MD, assistant professor in
family medicine was
selected by Prevention
Partners of North Car-
olina as co-recipient of
its first inaugural 2000
Physician Excellence
Prevention Award.
This award recognizes Goldstein

Goldstein's research, education and advoca-
cy efforts on behalf of tobacco use prevention
and control both in North Carolina and
throughout the nation.

Jack D. Griffith, MD, professor of microbi-
ology and immunology, has been named an
Ellison Medical Foundation Senior Scholar.
The honor carries an award totaling
$900,000 over four years. Griffith is one of
13 distinguished scientists selected from an
extremely competitive national field of appli-
cants. In granting these annual awards, the
Bethesda, Md. -based foundation said it aims
to "create a community of scholars in aging
that can foster the development of cutting
edge research." Last year, Griffith, and Rock-
efeller University colleague Titia de Lange
reported their discovery that the ends of chro-
mosomes, called telomeres, are tied in firmly
knotted loops. The discovery was heralded
worldwide as important for gaining insights
into cancer and aging.

Irva Hertz-Picciotto, PhD, professor of epi-
demiology, has been elected president of the
International Society for Environmental Epi-
demiology. Hertz-Picciotto is a founding
member of the society and a previous chan-
cellor on its executive board. The society,
founded in 1989, has more than 800 mem-
bers from more than 50 countries. Hertz-Pic-
ciotto also has been appointed chair of the
Committee to Review the Health Effects in
Vietnam Veterans of Exposure to Herbicides.
A National Academy of Sciences committee,
his group will create and issue a report to the
U.S. Congress that may influence the com-
pensation of Vietnam veterans for their
health problems.

W

^

Merry-K. Moos, MPH, has been recog-
nized by the Eastern
Carolina Chapter of
the March of Dimes
for her dedication to
improving the health
of mothers and ba-
bies in North Caroli-
na. On a national Moos
level. Moos serves on the March of Dimes
Nursing Advisory Council and has written
one of the most frequently-used nursing
modules entitled "Preconceptional Health
Promotion." She travels across the country
working with March of Dimes chapters to
educate health care providers about the im-
portance of working with women to make
sure they are healthy before they become
pregnant. Her involvement with the March of
Dimes reaches home to North Carolina
where she is a key member of the state Folic
Acid Council and a long-time chapter pro-
gram volunteer.

Oliver Smithies, PhD, professor of patholo-
gy and laboratory medicine, has received the
15th International Okamoto Award from the
Japan Vascular
Disease Research
Foundation for con-
tributions to medical
research. The award,
one of the most pres-
tigious given in
Japan, consists of 1 Smithies

million yen — about $10,000 — a gold
medallion and a certificate. According to the
citation. Smithies won the honor for "great
achievement in breaking new ground in the
hypertensive and arteriosclerotic research

12

field on the basis of molecular genetics." A
member of the UNC Lineberger Compre-
hensive Cancer Center, Smithies has earned
many international, national and state
awards, .\mong those were two Gairdner
awards, the Alfred P. Sloan Award of the
General Motors Foundation, the Ciba Award
of the American Heart Association, the Bris-
tol Myers Squibb Award for cardiovascular
and metabolic disease research and a North
Carolina Aw ard in Science.

In a 1995 profile, the New York Times called
Smithies "a scientific phenomenon, a man
whose intellectual pace has continued un-
abated for half a century.. .\\ ho continues to
break new scientific ground.""

Alan D. Stiles, MD, chair of the department
of pediatrics, has been appointed the first
Katherine M. Brewer Distinguished Chair of
Pediatrics and the Physician-in-Chief for the
N.C. Children's Hospital. Stiles is a 1974

Stilts

UNC graduate and a
1977 graduate of the
UNC School of Medi-
cine. He was chief resi-
dent in the department
of pediatrics at UNC
from 1981-82.

Kenneth M. Brinkhous. MD, w ho de-
veloped the first effecti\ e treatment for he-
mophilia and was the first scientist to
receive 50 years of continuous research
funding from the National Institutes of
Health, died Monday. Dec. 1 1 . 2000. He
was 92.

"Dr. Brinkhous was a truly remarkable
man, a gentle, soft-spoken scientific and
medical giant who pioneered treatment of a
terrible disease that afflicted, among oth-
ers, many of the royal families of Europe,""
said Jeffrey Houpt. MD. dean of medicine.
"Among his almost unbelievable list of ac-
complishments w as grow ing our pathology
department from almost a one-man
operation into one of the leading depart-
ments of its kind in the world. He will be
greatly missed.""

"A consummate scientist. Dr. Brinkhous
was a source of seminal research on the
mechanisms of blood clotting, an inspiring
teacher and mentor and a national and in-
ternational leader who helped to shape bio-
medical research in his time,"" said Stuart
Bonduranl. MD. former medical dean.
"His research contributions have saved and
improved the lives of tens of thousands of
children and adults in North Carolina and
around the world.""

Emeritus professor of pathology and
laboratory medicine at the LINC School of
Medicine. Brinkhous was an Iowa native
who attended the U.S. Military Academy
and received his bachelors degree from
Iowa State University of Science and Tech-
nology in 1929 and medical degree there in
19.12. The University of Iowa appointed
him to its faculty in 19.12. and he later rose
to the rank of Lt. colonel in the Anny Med-
ical Corps during World War II.

IN REMEMBRANCE

Kenneth M. Brinkhous. MD
The physician joined UNC as pathology
chairman in 1946. He wrote or contributed
to more than 450 research papers and
books, served on the editorial boards of 1 8
journals, including the Proceedings of the
National Academy of Sciences, and edited
four journals.

■'Kenneth Brinkhous was widely liked
and appreciated on campus,"" said his friend
and colleague John B. Graham, MD, distin-
guished professor of pathology and labora-
tory medicine emeritus. "He once said to
me that he may not be the smartest man in
the world, but no one is willing to work
harder. This was demonstrated not only at
his own institution, but also in national and
international arenas."

"All ol ihc ad\ances made in henu)|ihilia
were made on the basis of what was started
here in 1946 when Dr. Brinkhous came
here,"" said Harold R. Roberts, MD, Kenan
professor of medicine. "Fifty years ago,
many hemophiliacs did not survi\e to
adulthood. Today, patients with classic he-
mophilia can now li\e a \ iriually normal

life span because of the advances that Dn
Brinkhous made. His research is Nobel
Prize caliber.""

While at Iowa, Brinkhous discovered
that hemophiliacs could not make a blood-
clotting factor he named antihemophilic
factor and which now is called factor VIII.
Although not the diseases cause, lack of the
protein results in life-threatening symp-
toms such as uncontrolled bleeding. At
Chapel Hill, he and colleagues explained
the genetics underlying disease transmis-
sion and showed that henmphilia also oc-
curs in females.

They also dexeloped a test to detect clot-
ting disorders, the partial thromboplastin
test, that is still used millions of times a day
around the world and showed they could
control hemophilia by first replacing Factor
VIII through blood plasma. Another break-
through w as learning to purify and concen-
trate Factor VIII so that it worked fiu" better
Brinkhous also became a world leader in
explaining von Willebrands disease, the
clotting effects of snake venom and blood
clotting leading to stroke and heart attacks.

Among his many honors were the Amer-
ican Association of Pathologists top Gold
Headed Cane Aw;ird, election to the Amer-
ican Academy of Arts and Sciences, the
National Academy of Sciences and the In-
stitute of Medicine and honorary doctorate
degrees from Carolina and the University
of Chicago. He was named Alumni Distin-
guished Professor and recipient of the O.
Max Gardner Award from the UNC Board
of Governors, both \n 1961. The university
named both its Brinkhous-Bullitt Building
and an endowed professorship in his honor
In 1969. he received the North Carolina
Award in Science.

Faculty Profile

Meredith's Vision for

By Katie Macdonald

For those fortunate enough to have
20/20 vision, imagining a world of
muted tones or fuzzy images, is
difficult. But each day, people are
diagnosed with various eye problems that re-
quire corrective surgery, the use of glasses or
can even cause blindness.

That is why Travis Ashby Meredith, MD.
newly-appointed chair of the department of
ophthalmology, wants to ensure that his
department is a valuable resource for patient
referrals, research and teaching of local
physicians.

In doing so, Meredith feels ophthalmolo-
gists at UNC and beyond will be better
equipped to educate people about the causes
of vision problems and the new treatments
available.

"The issues of eye problems associated
with diabetes or macular degeneration,
which is often associated with old age, need
to be addressed by our medical center," he
said. "We must try to get the patient to see the
doctor and then it is our responsibility to pro-
vide the best possible care."

Bom in Welch, W.Va., Meredith grew up
with a passion for science and math and
thought that passion would lead him into en-
gineering. Instead, Meredith's career path
changed direction when he enrolled in a
human anatomy and physiology course his
senior year of high school. After taking that
class, Meredith realized how much he truly
enjoyed biology and decided at that point to
study medicine.

As an undergraduate at Yale University,
however, Meredith unconventionally ma-
jored in history. "Yale encouraged under-
graduates to do liberal arts," he said. "I had
not enjoyed history until I arrived at Yale, but
developed a great love for it there."

Meredith's love and devotion to history
won him the honor of being named a Nation-

Travis Meredith. MD. chair. Departmciitof Ophthabnology

14

Ophthalmology is 20/20

al Merit Scholar and pro\cd his dedication to
academics and high standards. Those high
standards helped Meredith mo\e on to his
next academic pursuit as a medical student at
Johns Hopkins University, where he re-
cei\'ed his medical degree.

Meredith chose ophthalmology after ex-
amining a patient's eye through a slit lamp, a
type of microscope used by ophthalmolo-
gists. "It's corny." he said. "But it was the
most unbelie\ able sight to me."

After completing an internship al Colum-
bia Presbyterian Medical Center. Meredith
returned to Johns Hopkins for his residency
at the Wilmer Institute of Ophthalmology.
During his residency, the Navy drafted him
to serve in Vietnam. "I was actually encour-
aged that the Na\ y drafted me," he recalled.
"There was this common knowledge that if
you were drafted by the Army or Air Force,
you would have to go to some flat place far
from civilization. But if the Na\y drafted
you. you got to float on a boat."

Meredith did none of the above. Instead,
he spent his tour of duty in Washington. DC.
and after only one year of training, was as-
signed as an ophthalmologist for the Main
Navy Dispensary, where his patients includ-
ed some of the most famous and infamous
politicians of the time.

Prior to his arrival at UNC. Meredith
served as a physician and faculty member at
some of the most respected academic med-
ical centers in the country, including the
Medical College of Wisconsin in Milwaukee
and Emory University in Atlanta. He also
served as the director of Vitreo-retinal
surgery at Johns Hopkins. Most recently, he
was a clinical professor of ophthalmology at
Washington University School of Medicine
in St. Louis. But Meredith made the decision
to move east when he learned of the opportu-
nity to teach at UNC.

"From my first visit, I ha\e been \cr> im-

pressed with UNC's medical center," said
Meredith. "UNC has high-quality faculty
w ith a strong record of success in attracting
research funding. But what makes UNC
unique is its collegiality and camaraderie.
While many academic medical centers are
shrinking because of budgetary constraints.
UNC seems vibrant and growing despite
these challenses," he said.

•• We must tiy to

get the patient to see

the doctor and then

it is our responsibility

to provide the best

possible care.

99

As chairman. Meredith wants to develop
and support a strong faculty who can carry
out the teaching and research fundamentally
important to an academic department.
Meredith plans to conduct patient care along
with other faculty members. His area of ex-
pertise is retinal disease.

Meredith puts a high priority on the treat-
ment of retinal diseases, which account lor
two of the leading causes of blindness, mac-
ular degeneration and diabetic retinopathy.
"Macular degeneration could easily be the
largest public health problem because it af-
fects so many elderly, the fastest growing
population group." he said.

Fye problems caused by diabetes also are
of paramount importance. But Meredith is
equally dedicated to improving the level of
treatment offered by UNC in a number of

other areas, including eye disease in prema-
ture infants, glaucoma, ocular trauma and
neurological disorders of the eye.

"He's very compassionate and down-to-
earth," Ricky Bass, the ophthalmology depart-
ment's business manager, said about
Meredith. "He wants to see the department go
a long way, and when it comes dow n to it, he's
got a good vision."

Bass describes Meredith's goals as rational
and for the good of the dep;irtment. "He w;ints
to know what's happening here at the medical
center and in the community," he said.

Meredith's skills as a physician and pro-
fessor have not gone unnoticed. His most re-
cent honor came in 1999 when he served as
president of the Macular Society, a group de-
voted to research in retinal disease. Meredith
has also belonged to other ophthalmological
societies, including the Retina Society, the
Vitreous Society and the American Ophthal-
mological Society. His experience in these
organizations and his years spent teaching
should provide Meredith vs ith the means to
take UNC's ophthalmology department to
the next level.

■"I feel my major respoiisihilily should be
to develop a long range plan for the depart-
ment working in conjunction with the facul-
ty." he said.

"We want to create a distmct |iath ol de-
velopment as we grow to tuirill our academ-
ic mission." D

News
Briefs

Sid Smith, MD, appointed
AHA's chief science officer

Sidney C. Smith Jr., MD, professor of
medicine and di-
rector of the
Center for Car-
diovascular Sci-
ence and
Medicine at the
University of
North Carolina
at Chapel Hill,
has accepted the
newly created
position of chief
science officer
for the American
Heart Association.

Smith

The role of chief science officer was cre-
ated to maintain the association's leadership
role in cardiovascular and stroke research,
as well as oversee the association's key sci-
ence initiatives and cultivate collaborative
partnerships with other organizations and
corporations.

Smith will maintain his appointments at
UNC. continue to see patients, work with
medical students, conduct research and pur-
sue academic projects.

"I will be speaking from the bedside and
on behalf of the American Heart Associa-
tion." Smith said. "Over the years, I have
been able to see first-hand the importance of
translating research findings to patient-care
initiatives. In this new position. I will be
able to use my experience to build important
partnerships for the association."

Smith has served the American Heart As-
sociation as a volunteer for almost three
decades. He led the organization as presi-
dent from 1995 to 1996 and served as a
member of the association's board of direc-
tors from 1991 to 1997.

Gary Park named chief
executive officer of
Rex Healthcare

Gary L. Park, chief operating officer of
the Moses Cone Health System in Greens-

boro, has been named chief executive offi-
cer of Rex Healthcare. His first day was Jan.
2. Eric B. Munson, president of UNC Hos-
pitals and chief operating officer of UNC
Health Care, served as acting CEO at Rex
since UNC Health Care acquired the Rex
system last April.

"Mr. Park is an accomplished health-care
executive who particularly distinguished
himself during the merger of the Wesley
Long and Moses Cone systems in Greens-
boro," Munson said.

Park, who was CEO of Wesley Long at
the time of the merger, served as chief oper-
ating officer of the combined systems
during a period of consolidation that's ex-
pected to deliver $55 million in merger sav-
ings by 2002.

"We are delighted to welcome Mr. Park
to Rex and to the UNC Health Care family."
said Jeffrey L. Houpt, MD, CEO of UNC
Health Care.

In Greensboro, Park, 49, was responsible
for the day-to-day operations of a 1 ,250-bed
system which includes three acute-care hos-
pitals, two skilled-nursing facilities and a
psychiatric hospital. Prior to serving as
CEO of Wesley Long from 1992 to 1997,
Park held senior executive positions at hos-
pitals in West Virginia and Florida. Park has
held leadership positions in the United Way
of Greater Greensboro and the Greensboro
Development Corp., and serves on the
boards of Hospice of Greensboro and the
Greensboro Arts Council. He received
his bachelor's and master's of public admin-
istration degrees from West Virginia Uni-
versity.

George Sheldon, MD, elected
chairman of country's
largest academic medicine
organization

The head of surgery at the University of
North Carolina at Chapel Hill School of
Medicine is chaimian of the Association of
American Medical Colleges, the largest
and most respected organizafion of its kind
in the country.

George F. Sheldon, MD, Zack D. Owens

distinguished professor of surgery, assumed
his new leadership post at the AAMC's an-
nual meeting Oct.
28 in Chicago.
Sheldon is an
expert in general
surgery, trauma
care and preven-
tion, burns,
oncology and
health- care work-
force issues who
joined the School
of Medicine facul-
ty in 1984.

Recently, on
behalf of its mem- ^'"^^''""

bers, the AAMC has sought legislative relief
from the 1997 Balanced Budget Act. The
act resulted in Medicare cuts more than dou-
ble the $1 10 billion Congress originally in-
tended, and about half of U.S. teaching
hospitals are projected to lose money this
year. Sheldon has testified several times be-
fore Congress about how the act has affect-
ed teaching hospitals.

One of Sheldon's goals as AAMC chair-
man will be to emphasize the importance of
clinical research and how it results in tangi-
ble new drug and medical therapies for soci-
ety. The country is experiencing a personnel
shortage in the fields of clinical research,
so the need to attract more people is critical,
he said.

"The National Institutes of Health has
identified clinical research as its second
biggest national scientific effort after the
Human Genome Project," he said. "Well-
trained people conducting clinical research
is a national need, and the issue becomes
more complicated as science becomes more
complicated."

Sheldon is the first surgeon who is not a
medical school dean since 1 879 to serve as
chairman of the AAMC. He is one of a
handful of surgeons in the past 100 years to
serve as president of all major surgical orga-
nizations, including the American College
of Surgeons, American Surgical Associa-
tion, American Association for the
Surgery of Trauma and American Board
of Surgery.

16

UNC's Consultation Center
Tiirns 15

Staff members and former employees of
the Consultation Center recently celebrated
15 years of providing North Carolina's physi-
cians with medical information, referrals and
a transport service.

"The Consultation Center has grown
tremendousK' o\er the \ ears and has helped
improve relations between UNC and North
Carolina doctors." said Andree Woosley. the
center's first director, during the October cel-
ebration.

Woosley recalled the center's beginnings
in the sub-basement of the intern quarters of
Medical School Wing E. That's where the
center's first three employees, along with
Woosely. worked answering calls and creat-
ing software for the program. Now. the Con-
sultation Center has logged more than
240.000 calls through its 24 hours a day,
seven-days-a-week service that promises to
connect doctors to UNC specialists in 90 sec-
onds or less.

Harold C. Pillsbury 111. MD. chief of oto-
laryngology head and neck surgery, senes as
the center's medical director. "Other places in
the United States have tried to do what our
Center does but have not been as successful."
he said. "For everv'thing UNC has aspired to
do o\er the last \5 years, the Consultation
Center get an A plus. Its success is a tribute to
everyone who helps provide this service."

wood, RN. staff the program. The Woman's
Heart Program opens Februai7 200 1 .

In other news, dramatic strides have been
made in the construction of the playroom
atrium in the new N.C. Children's Hospital.
Located on the seventh floor, the multi-sto-
ried room features an impressive view — all
the way into Chatham County — through a
large palladium w indow. The openness con-
tributes to the overall goal of the space: to
make it feel like a park setting in w hich chil-
dren can play. In recent weeks, workers have
installed gazebos and ramps, a rock fountain
and other equipment. A special type of floor-
ing that will provide a sense of grass as well
as a mock stream will complete the atrium.

UNC Health Care Practice
Closings, Expansions

The Community Health Center in Snow
Camp closed its doors at the end of 2000 due
to low patient \olume. "It was a hard decision
to make." said Jennifer Toney. former prac-
tice manager. "Most of the patients used the
Snow Camp clinic for urgent care and not an-
nual \ isits which help keep a clinic running."
she said.

A women's cardiology program is being
added to the list of ser\ices at Chapel Hill
North Medical Center. Eileen Kelly. MD.
Terry Thomas. RN. MSN. and Chris Green-

17

Research
Briefs

Carolina scientists first to
identify, purify liver stem
cells; a milestone for future
liver regeneration via cellular
therapy

After studies spanning more than a
decade, scientists at the University of North
Carolina at Chapel Hill have become the first
to identify and purify hepatic stem cells,
progenitor cells capable of regenerating liver
and bile duct tissue.

The accomplishment marks a milestone
for future liver regeneration through cellular
therapy, a treatment that could drastically re-
duce the need for whole-organ transplant in
people with a variety of liver diseases. The
current number of patients awaiting liver
transplantation is 15,700 nationally, but only
4,000 liver transplants have been performed.

"Liver transplantation for end-stage liver
disease is se\erely limited as a therapy for the
\ast majority of patients." said Lola
Reid, MD, professor of cell and molecular
physiology.

"Chronic end-stage liver disease accounts
for approximately 50,000 deaths annually in
the Lfnited States." she said. "Since one
donor organ helps only one or two recipients,
there is an increasing gap between donors
and transplant candidates over the past
decade."

In a report recently published in the Pro-
ceedings of the National Academy of Sci-
ences. Reid and research associate Hiroshi
Kubota. PhD. described another first: the col-
onization in lab dishes of a multitude of rat
hepatic stem cells from a single cell. "We are
the first to develop culture conditions that
permit one to put into culture these cells at
densities of a single cell in the dish and then
have it grow into a colony." Reid said.

"People have been putting mature liver
cells in culture for decades, but they always
had to put them in at \ery high densities or
they didn't survive. This meant you could
never ask whether a given cell was capable of
extensive growth or capable of producing
daughter cells of more than one fate. We now
have conditions in which a single cell can
be put in and it will survive and grow

extensively."

Liver cells are renow ned for their regener-
ative capacity in vivo, but in culture they
were found to go through only one or two di-
visions. No one could explain why. This was
exacerbated by the dogma in the field that all
liver cells are co-equal in their ability to grow
and restore liver tissue. Reid and her associ-
ates have shown that only the cells early in
the lineage are capable of repeatedly going
through complete cell division.

Reid"s research is funded by Renaissance
(Incara) and by the National Institutes of
Health.

For more information, see littp://
www.unc.edii/news/newsseiT/researclt/stem-
ceUU2200.htin

Cell studies may further gene
therapy prospects for head
and neck cancer

New laboratory research at the University
of North Carolina at Chapel Hill appears to
kindle prospects of finding ways to treat head
and neck cancer with gene therapy.

A study published in the journal Human
Gene Therapy suggests that gene-therapy
techniques may be developed to preferential-
ly target cancer cells or pre-cancerous cells
that are at high risk for becoming malignant.

"Right now there's no clinical application
of our work in human gene therapy, but find-
ings from our tissue culture model suggest
there may be." said Wendell G. Yarbrough,
MD, assistant professor of otolaryngology/
head and neck surgery.

Yarbrough. a member of the UNC
Lineberger Comprehensive Cancer Center,
said he and his collaborators developed a tis-
sue culture system that mimicked how nor-
mal cells grow in the body.

Using cultured cells, they created models
that mimicked the three-dimensional struc-
ture of head and neck epithelium, the normal
tissue that lines the inside of humans" mouths
and throats. This allowed a more realistic in-
vestigation of a widely studied gene transfer
technique that uses a common cold virus —
adenovirus — to infect cells and deliver ther-
apeutic payloads.

"If you take cells out of the body and put

them in tissue culture, they typically grow as
a monolayer, one cell layer thick," Yarbrough
explained. "But that's not the way they are in
the body. These can be infected by aden-
oviruses very easily. But if you let cells start
piling up on each other and differentiating the
way they do in the body, then it's very hard to
infect them."

Now it appears that the reason for that is
linked to whether or not the cells show gene
expression of a specific protein, a receptor
site known as hCAR, human coxsackie and
adenovirus receptor.

"And that's what we found." Yarbrough
said. "We correlated the ability of cells to be
infected by adenovirus with the expression of
hCAR. a receptor that's responsible for bind-
ing to adenovirus and getting it into the cells.
This is the first report of gene expression of
this receptor in normal human epithelium."

But that was only part of the story.

The researchers found it much more diffi-
cult to infect normal human oropharyngeal
(mouth) epithelial cells than it was to infect
oropharyngeal tumor cells.

The findings also carry possible implica-
tions for treating severe cellular dysplasia, a
precancerous condition characterized by cel-
lular abnormalities. These cells are undiffer-
entiated and like cancer cells express the
hCAR receptor.

For mare information, see http://
www. iinc.edu/news/newsserv/research/
tlwrapylJ2000.htm

Studies say delay in seeking
stroke treatment can lead
to death, permanent
impairment

People who think they or someone else is
suffering a stroke need to call 9 1 1 to summon
emergency medical service (EMS) immedi-
ately and not wait for any rea.son, according
to two new University of North Carolina at
Chapel Hill studies. That's the most effective
way to take advantage of a new clot-busting
drug known as tPA and possibly prevent
death or permanent impainnent.

The related studies, conducted at the UNC
schools of public health and medicine, fo-
cused on why stroke treatment often is de-

laved. Both appear in the November 2000
issue of Stroke, a pubhcation of the .Ameri-
can Heart .Association.

One. titled "Second Delay in Accessing
Stroke Healthcare (D.ASH 1 1 ) Stud)."" looked
at how patients and witnesses reacted to
stroke symptiims and tracked 6 1 7 patients ar-
ri\ing at hospital emergency rooms in Den-
ver. Chapel Hill and Green\ ille. NC.

Patients w ho used EMS had a median pre-
hospital delay of 2.85 hours, compared to
4.03 hours for those w ho didn"t use EMS.
said doctoral student Emily Schroeder and
her mentor. Wayne D. Rosamond. PhD. as-
sistant professor of epidemiology. But e\en
the 2.85-hour median elapsed time for pa-
tients using EMS is far too slow.

"It can take an hour or more to complete
and interpret necessary tests like a CT scan.
v\hich ha\e to he done before thromboly tic
(clot-dissoh ing) therapy can be given.""
Schroeder said. "The time a patient takes de-
ciding to seek care is the biggest portion of
the time between onset of symptoms and
treatment. Once EMS is alerted, things
can happen quickly, but people don"t call
9 1 1 unless they perceive their symptoms to
be urgent."

De.xter L. Morris. MD. \ice chair of emer-
gency medicine, led the second study, w hich
invoked monitoring 1.207 patients diag-
nosed w ith stroke or "mini-strokes"' at 48
hospital emergency rooms nationwide.

"There's a limited window of opportunity
of about three hours after the onset of stroke
symptoms in which the patient"s outcome
can be altered b\ thrombolytic therapy.""
Morris said. "This treatment appears to gi\ e a
patient a 30 percent better chance of ha\ing
minimal or no stroke-related disability.""

In that stud\. the Genentech Stroke Pre-
sentation Sur\ey. the median delay time be-
fore treatment was four hours and in some
cases, treatment w as not begun for more than
eight hours.

Delays were shortened when someone
other than the patient noticed their symp-
toms, which can include headache, dizziness,
confusion, loss of speech, \ision impainnent.
numbness and paralysis. Morris said. The
most significant factor in cutting time before
treatment was calling EMS quickly.

New drugs help more in
first-time schizophrenia than
older medications

People diagnosed w ith first-episode schiz-
ophrenia may fare much better when treated
with newer anti-psychotic drugs than
w ith traditional medications that were first
introduced more than 40 years ago. new re-
search indicates.

A study of 200 young adults in China by a
University of North Carolina at Chapel Hill
psychiatrist working w ith Beijing and Har-
\ ard Uni\ersity scientists is the first to direct-
ly coinpare treatment with clozapine, an
atypical anti-psychotic medication, with
chlorpromazine in people who had a
first episode of schizophrenia. None had ever
been treated for the disorder w ith these
medications.

In this double blind study, patients were
randomized to recei\'e treatment with one
drug or the other. Neither they nor the re-
searchers knew w ho recei\ed which one until
the data were analyzed. The findings clearly
filted in fa\ or of clozapine.

"We found that clozapine acts faster and
produced few er patients who drop out or stop
treatment because of side effects." said Jef-
frey A. Lieberman. MD. professor of psychi-
atry, pharmacology and radiology. "This is
the first time a study"s e\er been done com-
paring the prototype of this new class of
drugs w ith the old group in a large sample of
patients.""

Lieberman presented the findings Dec. 1 1
to the 39th annual meeting of the American
College of Neuropsychopharmacology in
San Juan. Puerto Rico.

Patients in the study whose blood tests
showed signs of exposure to the parasite tox-
oplasmosis responded poorly to treatment,
the study found for the nervous system,
where it can lie dormant for a long time in its
migration to the brain.""

Given this finding, the UNC psychiatrist
said a potential treatment strategy for schizo-
phrenia in a population with a high risk for
toxoplasmosis may be using standard anti-
psychotic medication along w ith one of the
drugs typically used against the parasite.

For more information, see http://\\\\w.
iinc.edii/ne\\s/newssen'/researcli/med 1 2 1 1 0
O.htm

Black men more likely to
suffer some osteoarthritis,
differences in women
weight-related, research
shows

Older black men in the L'nited Stales are
about 33 percent more likely than white men
here to suffer hip osteoarthritis, a new Uni-
\ersity of North Carolina at Chapel Hill
stud) shows. Weight diftercnces account for
comparable disparities in the degenerati\e
condition in women.

"We also found about the same proportion
of African-American men ha\ ing knee os-
teoarthritis as white men. but blacks were 65
percent more likcK to have it in both knees

and faced almost three times the risk of more
se\ere knee osteoarthritis."" said Joanne Jor-
dan. MD, research associate professor of
medicine. "We"re not sure why they get it
worse. It inight have something to do w ith
ph)'sical demands of w hat the) did at work,
but none of the things we looked at seemed to
explain the differences.""

Black women were about twice as likel)
as white women to develop the condition, to
get it in both knees and to experience greater
severity, the study showed. Those differ-
ences, however, appeared to result from
black women being heavier for their height
than white women, said scientists, who con-
trolled for obesit), age and education.

The study, presented at an American Col-
lege of Rheumatology meeting in Philadel-
phia. in\ol\ed 3.145 randoml) selected
people participating in the Johnston County.
NC Osteoarthritis Project, a U.S. go\ern-
ment-sponsored study that for the first time
includes many black subjects. Most investi-
gators consider the research to be the most
definitive study ever done on racial differ-
ences in osteoanhrifis.

A third of study participants, all over age
45. were black, and almost two-thirds were
women. UNC researchers found no differ-
ences in hip osteoarthritis in women of differ-
ent races.

From earlier studies in Africa and the
Canbbean. researchers expected to find little
hip osteoarthritis among U.S. blacks, and so
the new results were a surprise, Jordan said.
Differences may result from diet, bone densi-
ty disparities, genetic mixing or differing
work experiences. Or they may result from
some combination of the various factors.

"This study is important because it
show s, really for the first time, that African-
Americans ha\e more severe knee os-
teoarthritis than Caucasians do in the
L'nited States, and that most of this, in
women, is associated with greater bod) mass
index,"" the physician said.

Premature Delivery Led Doctor to Write Book
on 'Preemies' for Parents

For years as a physician, Mia
Wechsler Doron, MD. assistant
professor of pediatrics and social
medicine at the University of North
Carolina at Chapel Hill School of Medicine,
witnessed most of the problems facing "pre-
emie" parents. But the situation hit closer to
home several years ago when her sister,
Dana Wechsler Linden, gave birth to twins
almost three months early.

Doron, who researches decisions parents
and doctors make
about premature ba-
bies, recalled hours
spent with her sister
at the hospital, an-
swering the ques-
tions that brief talks
with other busy doc-
tors and nurses

couldn't satisfy.
Mici Wechsler Doron. M.D. ..t, , ,■

It made me realize

in a personal and powerful way that the in-
formation we give to parents is completely
inadequate to their needs," she said. "To pro-
vide it face-to-face in an individualized way
about each baby is impossible, because a
physician could never spend eight hours —
or even one hour — a day with every family.
It became obvious that just doctors talking to
families was not doing the trick."

Doron gave her sister and brother-in-law
the most popular book on premature births
— a gesture intended as a kindness. Only
later when the Lindens had brought their sur-
viving daughter home did she learn that the
book, largely out of date, offered little hope
to parents of preemies and heightened the
couple's fears and confusion.

The sisters and Emma Trenti Paroli, a
journalist Linden met when their infants
shared an intensive care unit room, put their
heads together. Paroli agreed with Linden, a
former Forbes magazine editor, that some-
one needed to write a book.

"We discussed the fact that parents of pre-
mature babies need a lot of complex, some-
times scary, information," said Doron. "To
keep their hopes and fears realistic, they

Jit fremature Babies

•s::t;r£5^

Vii

0^"^ Wechsler Unden.E^

si-'^'1:t^:t-'

'"a Trenti Parol/

need to hear only what
applies to their own child. We believe the
same infonnation — and good doctors know
this intuitively — can be given in a helpful
way to someone experiencing this trauma."

Combing their skills, the three wrote
"Preemies: The Essential Guide for Parents
of Premature Babies" (2000, Pocket
Books/Simon & Schuster).

According to reviews and sales figures,
the book is filling a void. Media coverage ex-
ploded with last week's New England Jour-
nal of Medicine article on outcomes in
extremely premature births.

Two years in the writing, "Preemies" con-
tains details about what happens to babies

'"'"W/a Wechsler Doron

M.D.

and when

and how various procedures are done. It is
divided into sections in such a way that par-
ents don't have to read bad news if it doesn't
apply to them.

"Clearly, this is not an experience just for
the baby," Doron said. "Other books have
not adequately addressed the notion that par-
ents — especially parents of extremely pre-
mature babies — undergo what may be the
worst experience they'll ever have — con-
templating the possible death and handicaps
of their child." D

20

Merrimon Lecture

The School of Medicine presented
this sear's Merrimon Lectureship
in Medicine on No\ember 8. Paul
E. Farmer. MD, PhD. co-director
of the FYogram in Infectious Disease and So-
cial Change at Hanard Medical School, de-
lixered the lecture. ""Pathologies of Power:
Medicine. Science, and the Future of
Human Rights.""

Farmer, u ho has w orked as medical co-
director of a clinic in rural Haiti and as med-
ical director of a community program in
urban Peru, spoke about the increasing in-
equalities in medical care among countries
with large cases of infectious diseases, such
as tuberculosis and HIV.

Farmer said increases in poverty and in-
equalities between the '"haves"" and ""hase-
nots"" in countries such as Haiti and Peru
leads to questions surrounding health and
human rights.

"There is a debate oxer treating people
with difficult to cure diseases and the author-
ities who say (the disea.ses) are too costly to
treat." Fanner said.

Farmer said there were no easy solutions
to eliminating the economic gaps, but many
organizations could work to set new agendas
for health and human rights. By working to-
gether to set new agendas, organizations
such as the World Health Organization can
help control and present diseases that ha\e
been described as incurable, he added.

■"We're living in an area of increasingly

Fanner speaks witli colleagues and students after delivering; his lecture on health and
human rights.

effective interventions. I believe we need to
broaden our coalitions and include more
people if it's going to work."

Farmer is an infectious disease physician
and anthropologist who has worked in tuber-
culosis control for over a decade.

The Merrimon Lectureship in Medicine,
which was established by Louise Menimon
Perry. MD. ""in respect and honour or the
Great Traditions of the Science and Practice
of Medicine." was inaugurated in 1966. O

Professor of Medicine and Associate
Chair for Education ./. Stephen Ki:er.
MD. chats with Whitehead Council
Co-Presidents Rodney Look and Janey
McGee. after giving his light-hearted
t(dk, "Warts Progress and Other
Things." at the JSth Whitehead Lecture
(Utd .Wards Cereinonx. .\long with
being this xear's Whitehead Lecturer,
Kizer was awarded the Kaiser-
Perinaiuiite Lxcellenc e in leaching
.\u (//•(/ in the clinical scieiucs.

Alumni Profile

Gifts To School of Medicine

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6('?n' Ann and Clarence Miller, Jr. MD '44 with one of their three racehorses.

By Ginger Travis

a

always wanted to be a farmer or a
doctor. And I always wanted to come
to Carolina."
Clarence M. Miller Jr.. MD "44. of
Wallace. NC. did come to Chapel Hill and
did choose medicine — decisions that helped
chart the path of his adult life through two
stints at UNC. Army service, a long and suc-

cessful career as a pathologist in Sewickley.
Penn.. a business startup and sale, and now
— closing the circle — a splendid gift to
endow a distinguished professorship and a
scholarship in the UNC School of Medicine.

The Clarence M. and Betty Ann Miller
Distinguished Professorship in Diagnostic
Pathology will support excellence in clinical
teaching and service. And the Clarence M.
and Eleanor Y. Miller Loyalty Fund Scholai-

ship will aid a deserving medical student.

"The cost to students going to medical
school is fantastic," says Miller, "and the
debt level of students is fantastic. They
should be helped privately as much as possi-
ble. Tm also giving the professorship as basi-
cally another way to help future students.
Research gets a lot of support: this is to sup-
port good teaching."

Charles Jennette. MD. chair of the depart-

Are All About Timing

ment of pathology and laboratory medicine,
says. "The Miller distinguished professor-
ship will recognize the preeminent impor-
tance of clinical instruction and service to
pathology. His gift will fill a void in our de-
partment, and we are deeply appreciative."

Miller arrived in Chapel Hill in 1939. al-
most 150 years after his famous relati\e.
Hinton James, walked to Chapel Hill to begin
his studies. (James, the first student to enroll
at the nation's first public university, showed
up for classes on Feb. 12.1 795. )

"I had a great time there, both as an under-
graduate and in medical school." Miller re-
calls. He li\ed in Ruffin dorm, played all the
sports he could, and did well enough in
chemistry to start medical school at Carolina.
He completed UNC"s two-year program in
1944 and then finished his medical degree at
Jefferson Medical College in Philadelphia —
where he also met his first w ife. Eleanor. The
.Army had paid his way through Carolina, so
he repaid the Army w ith ser\ ice in Korea and
Japan.

Once Miller realized he liked pathology,
he returned to Chapel Hill in 1951 as a teach-
ing fellow - a good time to be at Carolina
again. The late Kenneth Brinkhous. MD. was
just beginning his distinguished work. North
Carolina Memorial Hospital would open the
following year, and the whole pathology de-
partment was young, including the other fel-
lows. Margaret Swanton and George Penick.

"I just felt part of a team." says Miller "Dr
Brinkhous asked me to stay."

But he returned north tor two more years
of pathology training and finally settled in
Pennsylvania with his young family. He had
wanted a small town with a small hospital
near a university medical center, and .Sew ick-
ley, a suburb of Pittsburgh, fit the bill.

A decade or so later, he made an insesi-
ment that would pro\e \ery fortunate - and
that would enable him to make his generous
gift to the medical school. Because there was

no private lab to analyze tests perfomied by
physicians in the several small communities
nearby. Miller started one. His lab was later
bought out by a private regional lab — and
that lab in turn was eventually bought by the
Coming company. Dr. Miller used Coming
stock to make his gift to The Medical Foun-
dation of North Carolina. Inc.

A further combination of events helped
Miller decide on the timing of his gift to
endow a professorship and a scholarship in
the School of Medicine. Those events includ-
ed the death of his wife Eleanor in 1993. his
retirement, his marriage to Betty Ann. and
revisions he made to his estate plan.

At one point, he says, he had intended to
make his gift by bequest. But then Miller re-
alized that by establishing a charitable re-
mainder trust he could enjoy giving in his
lifetime - with many additional advantages.

The tmst will pro\ ide income to him and
to Betty Ann for both of their lifetimes, there-
by providing for her if he predeceases her.
And. funded with Coming stock, the charita-
ble trust is not liable for capital gains tax at
the time of the transfer. The charitable trust
also will greatly increase income to the
Millers over the amount produced by the
Coming stock dividend. Finally, the gift will
reduce his estate ta.x liability, just as a charita-
ble bequest would. And at the end of
Clarence and Betty Ann Miller's lives, the
Medical Foundation will use the gift, just as
Miller directed, to fund the distinguished
professorship and the scholarship.

The name of the professorship recognizes
his wife Betty Ann. and the name of the
scholarship recognizes his late wife Eleanor
"1 did this for the children." Miller says. (He
has three, including one Carolina graduate.
Richard.) "1 wanted the children to have
their parents remembered that way '

The young Tar Heel who in the I94()s
chose medicine o\er farming has kept in
touch u ith the land in al least a spoiling way:

The Miller's own a trio of racehorses —
Hariki. Festival Chairman and Sand Dollar
Sheik — which they board and race at a
small track in West Virginia. 45 minutes
from Sewickley. The purses are small, says
Miller, but so are the expenses. All good fun
— and another plunge by a North Ciuolinian
who w as never afraid to take a chance on the
future, n

This article first appeared in the
Winter 2000 issue of Carolina Corrections.

IN REMEMBRANCE

William B. Blythe, MD. a long-time
UNC physician wlio uiuglit and treated
thousands as he helped shape the medical
school died Dec. 21, 2000. at age 72.
Former student David A Tate. MD'82.
associate professor of medicine in the
division of cardiology, offers this tribute.

As a native North Carolinian, I learned
as a child that our state tlower was the dog-
wood and our state bird was the cardinal. I
learned how we came to be called Tar
Heels, and I could even hum a few bars of
"The Old North State." I learned from our
license plates that we were the "Variety Va-
cationland" and the "First in Flight. It
wasn't until much later in life, however,
that 1 learned our official state motto —
"Esse Quam Videri." No advertising slo-
gan this; the.se were real words written by
real men — words to live by. This Latin
phrase means "to be, rather than to seem,"
and it graces The Great Seal of the State of
North Carolina. By legal statute, "no other
words or other embellishments shall ap-
pear on the seal." The man who introduced
me to these words was Dr. William B.
Blythe.

This would be but a personal remem-
brance, hardly worthy of publication.

William B. Blythe, MD

except for the
fact that he
taught the
word and
spirit of this
phrase not just
to me, but to
thousands of
students and
colleague
during his
more than 50
years at the
University of
North Carolina School of Medicine. The
sadness accompanying Dr. Blythe's
untimely passing may be tempered .some-
what by a reflection on his prodigious
legacy. He taught generations of physi-
cians and scientists how "Esse Quam
Videri" could be as central to a man's life
as it is to our state seal. Dr Blythe was ab-
solutely successful but absolutely huinble.
He was elegantly simple and simply ele-
gant. He was completely without pretense.
He took everything he did seriously but
never took himself too seriously. He was
genuinely curious and inquisitive about
everything and anything. He never cared

about appearances or short-temi gains, but
instead had the wisdom and perspective to
steer the university toward rock-solid,
durable excellence. He spoke and wrote
from the heart. He taught us by example
what it meant to be the real thing - a real
doctor, a real scientist, a real teacher, a real
leader, a real citizen, a real husband, father,
son or brother, and a real friend. In short,
"Esse Quam Videri" was never more truly
embodied than in William B. Blythe. Bill
loved the State of North Carolina and The
University of North Carolina, but, more
importantly, he loved his family, friends,
students, and colleagues. I know he would
be pleased if we chose to memorialize him
by striving to live in accordance with the
motto of his beloved state.

For all his learned ways. Dr. Blythe en-
joyed nothing more than a long walk in the
woods. He made a notation each year of
when he would hear the first wood-thrush
call in the Spring — always, he would tell
me, within a day or two of April 1 7. I'll
miss you. Bill, when I hear the first flute-
like call this April, but I know you'll be
smiling to know that I made the notation
for you. D

Honor Roll Corrections

The Fall 2000 issue of the Bulletin includ-
ed the Medical Foundation's annual "Report
to Donors," which features an Honor Roll of
Donors who made contributions to the Loy-
alty Fund during the preceding fiscal year.
Unfortunately, not all names were included.
Names in bold type recognize alumni who
contributed $1,000 to $9,999. Names in ital-
ics recognize alumni who contributed
$10,000-1-.

Our apologies to those donors whose
names appear below. Thank you again for
your generous support of all programs at
your alma mater

Mark J. Abrams, MD '92, Rock Hill, SC
James R. Auman, MD "71, Chesapeake, VA
Elizabeth S. Babcox, MD '81, Shaker Heights,
OH

H. Wallace Baird, MD '69, Greensboro, NC
Pauline M. Blair, MD HS, New Bern, NC
Carol A. Borack, MD "98, Rochester, NY
Richard A. Boyd, MD '56, Statesville, NC
Maurice Castillo. MD Faculty, Chapel Hill. NC
Elizabeth T. Clark, MD '86, Oak Park, IL
William M. Clark, MD '86, Oak Park, IL
Robert J. Cowan, MD "63. Winston-Salem. NC

Thomas C Darrell. MD "83, Fuquay-Vanna, NC

LisaF Dejamette, MD "86. Raleigh, NC

Carrie Dow-Smith. MD '97, Pearland, TX

Joanne Earp. PhD. Chapel Hill, NC

Charles H. Edwards II, MD '73. Charlotte, NC

Su.san T. Edwards. MD '76. Norwich. VT

Karolyn Forbes. MD "98. Ann Arbor. MI

Sheryl A. Gillikin. MD '83. Fayetteville. NC

Mary B. Colby. MD "50, Durham, NC

Karen L. Grogg. MD "98, Rochester. MN

Timothy R. Heider MD '99. Chapel Hill. NC

William H. Jamian. MD '67. Gastonia, NC

Dr. and Mrs. William R. Jordan, MD '70,

Fayetteville. NC

Shannon C. Kenney, MD HS, Chapel Hill, NC

Janice D. Key, MD '80, Hollywood. SC

Helene R Key zer- Pollard, MD'91 . Gastonia. NC

Joseph W. Kittinger MD HS. Wilmington. NC

Thomas J. Koontz, MD '66, Winston-Salem,

NC

Constance F Letler PhD. Fort Worth. TX

Victona D. Lackey. MD '92. Charlotte. NC

H. Lee Large Jr., MD '40, Charlotte, NC

Catherine K. Lineberger. MD "87. Chapel Hill.

NC

Dugan W. Maddux. MD '84. Danville, VA

Robert S. Miller. MD "99, CincinnaU, OH

David K. Millward, MD HS, Raleigh, NC
Jackie A. Newlin-Saleeby, MD '83, Raleigh,

NC

John B. Piecyk. MD "93. Canton. MA

Harold C. Pilkbury, MD HS, Chapel Hill, NC

William C Powell. MD HS. Fayetteville. NC

Veronica J. Ray. MD "79. Durham. NC

Amy J. Robbins. MD "9 1 . Charlotte. NC

Patricia K. Roddey. MD "91. Chariotte. NC

Yolanda V. Scarlett. MD '89. Hillsborough. NC

Stephen R. Shaffer MD "63. AsheviUe. NC

Amy W. Shaheen. MD HS. Chapel Hill. NC

Martha K. Sharpless, MD '59, Greensboro,

NC

Nicole R Shepard, MD HS. Albany. GA

James A. Shivers, MD '71, Asheville, NC

Barbara H. Smith. MD "83. Greensboro. NC

G.R. Smith. MD "5 1 . Shawsviile. VA

Linnea W. Smith, MD '76, Chapel Hill, NC

Vincent C. Smith. MD "97. Pearland. TX

Benjamin D. Thomas, MD "80, AUanta, GA

Rebecca B. Tobin, MD "93. Chapel Hill. NC

Deborah L. Tussing, MD '83, Severna Park,

MD

George D. Wilson. MD "72. Johnson City. TN

Solomon G. Zerden, MD '76, Savannah, GA

Sherri A. Zinimemian. MD'91, Cary. NC

24

Development
Notes

Novo Nordisk establishes
professorship to honor
renowned hematology
researcher

Novo Nordisk PhurmaceuticalN Inc. has
donated SI million to establish the Harold
R. Roberts Distinguished Professorship
within the Uni\ersity of North Carolina at
Chapel Hiirs Center for Thrombosis and
Hemostasis.

Roberts. Sarah Graham Kenan professor
of medicine and pathology in the UNC
School of Medicine, is the founding direc-
tor of the Center for Thrombosis and He-
mostasis. which studies blood-clotting
disorders related to cardio\'ascular disease
and bleeding disorders. He is recognized
internationally as an expert in hematology
and was the first U.S. physician to treat he-
mophilia patients w ith factor Vila, a med-
ication that has been extremely successful
in treating hemophilia patients not respond-
ing to older or other products.

Martin Soeters. president of Novo
Nordisk Pharmaceuticals. Inc.. said the
company was proud to recognize Roberts"
achievements within hematology research
by honoring him with this endowment.

■"We appreciate just how critical Dr.
Roberts" research has been in the develop-
ment ol effective means of treating bleed-
ing disorders, particularly hemophilia,""
said Soeters. "He has dexoted his entire ca-
reer to ad\ancing research in this field, so
that people who have these disorders may
hu\e full and active lives. We hope that this
professorship will further encourage the
strong Carolina tradition in this vital area of
medical research. No\() Nordisk is particu-
larly interested
in ad\ancing
this field and
has recently
introduced
Novo Seven,
recombinant
factor VII. in
ihel'.S.""

The univer-
sity has
received ap-
proval for a

Excellence Fund Awards Five Grants

The Medical Foundation of North Carolina. Inc.. recently awarded seed grants from
its Excellence Fund to five centers at UNC. The S5.0()() grants went to the Thurston
Arthritis Research Center, the Bowles Center for Alcohol Studies, the Lineberger Com-
prehensi\e Cancer Center, the Cystic Fibrosis/ Pulmonary Research and Treatment
Center and the Center for Maternal and Infant Health. The Excellence Fund is an ure-
stricted annual fund for non-alumni through the Medical Foundation.

Plans for the seed grants range from using the money to research birth defects caused
by alcohol (Bowles Center), funding innovative approached to cancer research
(Lineberger). and purchasing equipment for junior faculty and sending trainees to na-
tional meetings (Cystic Fibrosis/Pulmonary Research and Treatment Center). Other re-
cipients have not yet made specific plans for the seed money.

Pictured left lo right arc: Jim Copeland. Foundation president ; Robert Devellis. PhD.
Thurston Arthritis Research Center; Kaih\ Sulik. PhD. Bow les Center for Alcohol
Studies; Lucy Siegel. The Center for Maternal and Infant Health; Anne Hager-Blunk.
Foundation senior de\ elopment officer; and Shells Eaip. MD. Lineberger Comprehen-
sive Cancer Center Not pictured is Rick Boucher. MD. Cystic Fibrosis/ Pulmonar\ Re-
search and Treatment Center

HarnUI R. Roberts

$.^.^4.()()() challenge grant from the Distin-
guished Professors Endowment Trust Fund
of the State of North Carolina lo bring the
endow ment to S 1 ..^.U.( )()().

The search for a candidate for this pro-
fessorship is scheikiled to begin in the sum-
mer of 2(K) 1 . and the professorship could be
awarded as early as 2002. liligible candi-
dates arc current UNC Center lor Throm-
bosis and Hemostasis faculty members or
researchers from outside the university who
are internationally renowned for work w ith-
in the field of bleeding disorders.

A native of Four Oaks. NC. Roberts
earned his bachelor"s degree anil medical
decree from UNC". where he was Phi Beta

Kappa and Alpha Omega Alpha. He joined
the UNC faculty in 1962 and has served as
chief of the division of hematology and di-
rector of the L'NC" Comprehensive Hemo-
philia Diagnostic and Treatment Center

Novo Nordisk is a focused healthcare
company anil the world leader in diabetes
care. In addition. Novo Nordisk has a lead-
ing position w ithin areas such as coagula-
tion disorders, growth disorders and
hormone replacement therapy. Novo
Nordisk product Novo.Seven Coagulation
Factor Vila (Recombinant) is indicated for
the treatment of hemophilia .A and B pa-
tients with inhibitors.

25

A Student Proves
It's Never Too Late

Martha Peck and faniih
Martha. Ray and David.

By Katie Macdonald

She doesn't quite look like the other
students. And even though she looks
older, she doesn't look old enough to
be a student's mother. She appears to
lack the "first year jitters", so she couldn't
possibly be a student. But that's exactly what
she is.

First-year medical student Martha G. Peck
is getting a taste of student life for the first
time in. well let's just say. many years. She's
a wife and a mother of two teenage sons and
most recently served as the vice president of
the Burroughs Wellcome Fund, an indepen-
dent private foundation in Research Triangle
Park dedicated to supporting scientific re-
search and education.

So, why medical school after so many
years working in the private sector and hav-
ing a family? Peck's childhood, background
in pharmacy and inherent love of medicine
are factors that raised the \olume of her inner
voice telling her to "go back."

Growing up in Greensboro. Peck spent
many of her summers working in a physi-
cian's office and the rest of the year as a hos-
pital volunteer. Her home life, which
included a nurse mother, a pharmacist neigh-
bor and doctor relatives, rounded out the
medical influences that would later drive
Peck's decision to concentrate her energies in
health-related fields.

"I have always reveled in the sights,

26

all siiuUs after the White Coat Ceremony. From left: Ju.son.

sounds, and smells of medicine," said Peck,
taking time out for an interview between
morning classes and an afternoon gross
anatomy lab. "I think I've always known that
medicine was what I truly wanted to do."
she added.

Before she would finally make it to the
medical school. Peck received a BS degree in
pharmacy from UNC in 1 974. married, start-
ed a fainily and then served as the vice presi-
dent of a well-respected research foundation.
"I don't regret not going to medical school
earlier." she said. "I've had so many
wonderful opportunities that have led me to
this point."

In the essay Peck submitted with her ap-
plication to the medical school, she wrote:

"So why medicine, why now? I believe
my unique combination of pharmacy, phar-
maceutical, and foundation experience pro-
vides substantial opportunity to contribute to
medicine."

Peck also wrote that she wanted to focus
her studies on geriatric medicine. "Geriatrics
has long held my passion and interest." she
said, citing statistics that by 2015 one in five
Americans will be over the age of 65. She
worries, however, that geriatric medicine,
based on current trends, is not expanding as
fast as the patients. More physicians to help
the elderly will be needed.

But concentrating on geriatrics is a few
years down the road for a student who re-
ceived her white coat at Family Day festivi-

ties in September.

That day. Peck was joined by her husband
Ray. a vice president of investments at Legg
Mason. Inc.. and her two sons. Jason. 16. and
David. 13.

And what does her family think of her re-
turn to academia? "I think it's great." Jason
said. Peck looks at him lovingly, but apolo-
getic all the same. She possesses in that one
look her anticipation for the future and the re-
alization that her decision to choose a life of
medicine will sometimes take her away from
her family.

But it's all a part of fulfilling the dream.
She has no doubts that she is fully prepared
and qualified to live up to the demands of
medical school and later a career in geriatric
medicine. "I think I have a broad knowledge,
diverse experience, and a proclivity for lead-
ership." she says. With that attitude, she may
not be the typical medical student, but she
certainly is one of the most promising. D

Class of 2004 profile

48 of the 160 students are female.

Ages range from 1 8 to 47. with the
average age 23.

69 percent are Caucasian. African
Americans comprise 14 percent of the
class, Asians make up 13 percent.

88 percent are North Carolinians at the
time of admission.

All of the students have bachelors
degrees, most in biology and chemistry.
Masters degrees are held by 1 3 mem-
bers of the class. Two have doctoral
degrees.

Alumni
Notes

50s

Garland E. Wampler. MD "56. announces
his retirement. He and his wife Mar> .Ann
have two granddaughters, ages 12 and 16.
The couple recently returned home to
Bumsville. NC. from a four-day trip to Vir-
ginia's Colonial Williamsburg.

M. Paul Capp. MD. '58. received the
Roanoke College Medal, the highest honor
bestowed on its alumni. Today. Capp is the
executi\ e director of the .American Board of
Radiology, a position he earned after ser\ -
ing as trustee and president of the board. He
has recei\'ed three gold medals from the
Association of University Radiologists.
American Roentgen Ray Society, and in
1999. the American College of Radiology.
He's also a Fellow of The Royal Society of
Medicine in London.

60s

Robert H. Hackler, MD "60. is a professor
of urolo2\ at the Medical Collese of

Virginia and chief of urology at McGuire
Veteran's Hospital. He was honored with
the Bunts-Hackler Lectureship in Decem-
ber. 2000.

Dave M. Davis, MD PC "63. is the medical
director of Piedmont Psychiatric Clinic in
Atlanta. Practicing psychiatry is still his
love. He recently visited France w ith Ipa
Hardy ('63) and John Foust ( '59).

David C. Hefelfinger, MD "65. retired in
March 2000 as professor and chairman of
the department of pediatrics at the Uni\ersi-
ty of Alabaina. He's been spending time
playing golf. tra\eling. reading, writing,
wine tasting and in part-time pediatric w ork.
Hefelfinger plans to tra\el to Kampalla.
Africa, to teach at Mulago Hospital in 2001 .
E-mail him at dchefel@aol.com.

A.L. Roper, MD "67. is enjoying his retire-
ment in Norfolk. Va.. by working as a deck
hand. He is imolved with OpSair2000. The
Great Chesapeake Bay Schooner Race, and
anvthins else ha\ ing to do with salt water.

70s

Joe Bill Putnam, Jr., MD "79. is now a
professor. di\ ision of surger*. department of
thoracic and cardiovascular surgery at the
University of Te.xas M.D. Anderson Cancer
Center. For the past four years, he's also
served as deputy chairman of the depart-
ment of thoracic and cardio\ ascular surgery
where he concentrates on thoracic
surgical oncology. Email him at
putnam @ mdanderson.org.

Alan M. Ranch, MD, "79. is now senior
vice president for clinical affairs at Miraxant
Medical Technologies in Houston, Tx.

80s

Kenneth E. Hollingsworth, MD '80. re-
sides in Georgetow n. De.. w ith his new
bride Stacy LaMotta. He retired from the US
Navy this fall and is currently working as an
anesthesiologist in private practice at Nauti-
coke Memorial Hospital in Seaford. De.

UNC Department of Psychiatry bestows
distinguished alumnus award

The UNC Department of Psychiatrs
named Charles B. Nemeroff. .VID '81. its
George C. Ham Society Distinguished
,\lumnusfor2fXK).

Nemeroff. the Reunette W. Harris pro-
lessor and chair of Emor) University's de-
partment of psychiatry and behavioral
sciences. recei\ ed the aw ard No\ . 1 8 dur-
ing the department's annual George C.
Ham Symposium.

.N'emeroft. who earned both his medical

and doctorate degrees at UNC. is well-
known for his research into the biological
causes of major neuropsychiatric disor-
ders, including affecti\e disorders.
Alzheimer's disease, schizophrenia and
anxiety disorders. He received the UNC
School of Medicine's Distinguished Ser-
vice Award in 1999.

•Associate editor ot Biological Psychia-
try. Nemeroff ser\ es as co-editor-in-chief
of both Critical Reviews in Neurohioloiix

and Depression and Anxietx . and is the co-
editor of the Textbook of Psychopharma-
cologN published b\ the American
PsNchialric Association Press, now in its
second edition. He serves on the Menial
Health Advisory Council of the Natii)nal
Institute of Mental Health, and is past
president of the American College of
Neuropsychopharmacology and presi-
dent-elect of the .American College ol'
Psvchiatrists.

27

Terance L. Lamb, MD '85, is practicing in-
ternal medicine at Wyman Park Medical As-
sociates in Baltimore. The practice is part of
Johns Hopkins Medical Services Corpora-
tion.

90s

Crystal Duncan Katz, MD '91, and Seth
Katz, MD, '91. celebrate the arrival of their
son Alexander Duncan Katz on Oct. 24,
2000. He has an older sister, Isabelle, age 2.
Crystal is an anesthesiologist and husband
Seth is director of infertility services at the
University of California at San Diego.

W. Kent Guion, MD '92, is an associate pro-
fessor in the department of health and kinesi-
ology at Geroge Southern University. Guion
also is director of the center for rural health
and research. He and wife Jeannine wel-
comed their first child, Sydney Nicole, in
August 2000. Email him at kguion@
gsaix2.cc.gasou.edu

Peter R. Young, Jr., MD '92, after working
for 2 1/2 years in a private general surgery
practice in Raleigh. NC. is leaving for Yaki-
ma. Wa. to join Cascade Surgical Partners.

Loretta Kaus Tibbels, MD '93, recently
welcomed Nicholas Stephen Tibbels into the
world. Nicholas joins his three big sisters,
Stephanie. 5, Lauren, 4, and Danielle, 2.
Tibbels works as a clinical assistant professor
with Nebraska Health Systems.

Wendy J. Grant, MD '94. was recently
named fellow for solid organ transplant at the
University of Nebraska. She completed her
general surgery residency at the University of
Utah in July 2000.

Michael K. Champion, MD '96. was

awarded the Rappaport Fellowship by the

American Academy of Psychiatry and the
Law. He began a fellowship in forensic psy-
chiatry at Yale University in July 2000.

Deaths

Ralph B. Garrison, MD '31
Charles F. Scarborough, Jr., MD '44
David Jay CoUender, MD '89

28

President's
Letter

In the tiny Appalachian coal-mining
town of Whitesburg in eastern Ken-
tucky. I sened tw o years w ith the Na-
tional Health Ser\ ice Corps. Though its
abject isolation was initially painful for
Diane and me. it turned out to be an in\alu-
able experience, one that I still draw from
now. 1 2 years after our leaving.

I remember one patient, an unassuming
world-class fiddler w ith a brief touring ca-
reer, who tried unsuccessfully to pass some
of his skill to me. Despite his musical gift, he
lived in poverty. The roaches crawling along
the interior walls of his trailer remain a vivid
memory. Mr. Sumner, now deceased, proba-
bly ne\er even noticed the creatures in his
home. He seemed obli\ ious to many of the
everyday concerns that burden the a\ erage
person. His w idow and I continue to ex-
change Christmas cards.

Another patient, a retired gentleman w ho
lived in a hollow fully four miles back into
the woods, shared his love of woodworking.
Specifically, he was reared in the art of
woven hickory bark seats and chair backs.
With tobacco-brow ned points for teeth and a
monthly go\emment income of about SSOO.
he was not the picture of success. Yet his four
or five annual projects were suftlcieni lor his
unhurried brand of contentment. Not betore
or since ha\e I met anyone happier than he.
One of his rocking chairs, made from my
sketch, occupies a comer of my living room.

All of this brings me. circuitously. to my
Methodist minister in Whitesburg. He was a
good soul overall, but battle-worn and cyni-
cal far beyond his .^2 years. Once, he ex-
plained to me that he avoided "money
sermons'" because thes in\ iled the congrega-
tion to ser\e up their favorite Sunday dinner
— Roast Preacher. He was only hall kidding
and my own experiences have since shown
that money is indeed an incendiary topic. I
have learned to tread lightly.

Thai said. I nonetheless forge ahead to

make the case for alumni financial support of
our medical school. Please consider these
facts:

UNC School Of Medicine t jition, in-state, 1 980 . . , $980
UNC School of Medicine tuition, in-state. 2000 $3,220

Duke Medical School tuition, 1980 $6,300

Duke Medical School tuition, 2000 $27,600

Actual cost of medical school, estimated . . $1 00,000
Average US physician income (1999) $163,170

Clearly, there can be only one reasonable
response to these figures — gratitude. To-
ward whom do we express this gratitude'.'
Where does the School of Medicine get the
bulk of its support?

First, research grants and contracts gener-
ate the largest proportion of revenue for your
School of Medicine. As shown in a pic graph
in the 2()(){) Donor Report of the Medical
Foundation, fully 36 percent of the $47.^ mil-
lion total comes through faculty who com-
pete successfully for funding from NIH and
other sources.

Second, clinical care accounts for 24 per-
cent of medical school income. As known all
too well by those of us in practice, managed
care and other factors steadily erode practice
receipts as expenses climb skyward year
after year. Maintaining fee-generated income
is an even greater challenge for UNC which
shoulders a disproportionate share ol uncom-
pensated care.

Ranking third among the School's funding
sources is slate taxpayer support. At I S per-
cent, this comes as a surprise lo many North
Carolinians — including many of our own
medical alumni — who have believed that
I INC School of Medicine's financial health is
secure because of it is a state-assisted mstiiu-
lion. As you can see from the percentages
above, financial strength must be earned
anew each year. Hven in the heady afterglow
of the higher education bond campaign
which will hriiiij a iranslonniiiL! SSS million

to the medical campus for new buildings
and renovations, added funding is still need-
ed for competitive salaries and other operat-
ing expenses.

Yes, we alumni are deeply in debt to others
for our medical educations — faculty,
patients, taxpayers, benefactors. But this tleht
is not an onerous burden. Rather, it is a
tie that binds us proudly together. Our
happy privilege is to respond with ongoing
tinancial support.

/'(/(// V'/.vc/; Prcsidtnl

CME/Alumni Calendar

February 16. 2001 - Chapel Hill

Community Service Day

February 27, 2001 - Hope Valley Country Club, Durham
Deans Reception for Durham-Orange Counties, 7-8:30 p.m.

March 1, 2001 - Mint Museum of Art, Charlotte

Dean's Reception for Mecklenburg County. 7:8:30 p.m.

March 1, 2001 - Chapel Hill

Neuro-Ophlhalmology Review

March 7-9, 2001 - Chapel Hill

2.'ith Annual Internal Medicine Conference

March 22-23, 2001 - Chapel Hill

High Functioning Autism

April 3, 2001 - Country Club ofAsheville

Dean"s Reception for Buncombe County. 7-8:30 p.m.

April 8-12. 2001 - Waikoloa, Hawaii

Breast Imaging: Digital Mammography Update "01

April 10, 2001 - Chapel Hill

Emergency Medicine Research Forum

April 11, 2001 - Cape Fear Country Club, Wilmington

Dean's Reception for New Hanover County. 7-8:30 p.m.

April 27-29, 2001 - Chapel Hill

UNC Medical Alumni Association Spring Weekend

For more information about CME courses, contact the Office
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Eye on the Future:

UNC and the

Genomics Revolution

y

Dean's
Page

In mid-February the world was present-
ed with a map of the human genome.
Today we begin a journey to understand
how genes do their work and how it af-
fects people, animals, and plants. In this
dawning genomics era. discoveries will con-
tinue to astound, each having a potentially
profound effect on our understanding of
human life and how our genes predispose
and protect us from disease. Medicine and
how it is practiced will be enormously affect-
ed as we move from a reactive stand of treat-
ing established disease alone to a proactive
one of preventing the onset of disease as well.
To meet these discovery challenges, UNC
has initiated an unprecedented phase of
growth and expansion in human genetics,
molecular genetics, gene expression, devel-
opmental genetics, genome mapping and or-
ganization, genetic epidemiology and
biostatistics. The result is exciting research
programs and training in all aspects of
genetics, in organisms ranging from plants,
fruit fly and nematode to mouse and human.

This initiative in genetics and genomics
has led to the establishment of a new Depart-
ment of Genetics within the School of Medi-
cine and a university-wide center for genetics
and genomics: the Carolina Center for
Genome Sciences.

Last month, details of the University's
major investment in genome sciences were
announced at a special event in Chapel Hill.
Hosting the event was Chancellor James
Moeser. He said that "this new era for discov-
ery at Carolina has been shaped by our past."
The Chancellor noted the "rich histoiy of pi-
oneering work in the social sciences: leg-
endary quality in the humanities; and
outstanding multidisciplinary research in all
five health sciences schools that long has
tapped the expertise of colleagues across the
campus in other disciplines as well."

Using conser\ative estimates, we are com-
mitting $245 million over the next 10 years to
programming, faculty positions, start-up
costs, and new buildings to support genome

sciences. That is a significant total among
major public and private universities and a
strong indication of how important genome
sciences is in our strategic thinking about
Carolina's future.

Much of the credit for establishing this
$245 million initiative goes to the Deans of
the various schools and the Provost. Togeth-
er, the Deans reallocated 22 positions, taking
them from old programs. The Provost and
Chancellor committed 1 8 new positions from
new endowment monies.

Equally important are our partners in this
investment off campus. They include the
people of North Carolina with their votes in
last year's historic statewide bond referen-
dum: members of the North Carolina Gener-
al Assembly; the federal government and our
state's Congressional delegation: and private
foundations and individuals.

Of these partnerships, I want to highlight
two investments:

• An anonymous $25 million donation to cre-
ate the Michael Hooker Center for
Proteomics in the School of Medicine. This
genetics .specialty area involves cataloguing
proteins expressed in cells — a topic that is
particularly timely given recent reaction
among scientists about the potential role of
proteins in the entire human genome puz-
zle.

• A $2.25 million federal government invest-
ment to provide program and infrastructure
support, including lab equipment. This
appropriation resulted from efforts
by Chapel Hill's own David Price and
congressional colleagues, including Sena-
tor Jesse Helms, to secure it as part of the
federal budget finalized last Deceinber.

The biological revolution being spawned
by the genome sciences has enormous poten-
tial to help humanity and at the same time
create a significant economic impact. But it
raises a broad range of social, psychological,
and ethical issues that we as a society are not
yet prepared to answer.

The complexity of what lies ahead certain-
ly will hinge a great deal on the science, but

we know it must go far beyond experiments
in a laboratory or with treatments in a clinical
setting. That is precisely why the effort here,
will be university-wide, joining medicine,
the other health sciences, the College of Arts
and Sciences, and professional schools such
as Law and Infomiation and Library Science.

In Terry Magnuson. PhD. one of the most
highly sought-after scientists in mammalian
genetics, we have recruited the best person in
the country to lead this initiative and build
upon our many strengths here in Chapel Hill.
In turn, he has led efforts to persuade some of
the world's leading scientists that our collab-
orative culture is worth a move, even across
oceans. This campus is energized, and we
have set our sights high.

I hope you will follow with me our leader-
ship in the tleld and enjoy the excitement it
will bring.

(^^^

ihj^t

Jeffrey L Hoiipr. MD
Dean. School of Medicine

Medical Alumni
Association Officers

President

Paul E. Viser. MD "84
Clinton

President-Elect

Thomas J. Koontz. MD "66
Winston-Salem

Vice President

Ray M. Hay worth. MD "62
Knoxville, Tn

Secretary

John M. Herion, MD "83

Wihniiif^ton

Treasurer

William M. Heradon. Jr.. MD "81
Charlotte

Editorial Staff

John W. Stokes

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Marketing;

Debra Pierce
Manai^iniJ Editor

Leslie H. Lang. Katie Macdonald.
Pam Pearce. Lynn Woolen.
Eleanor Yates
Conirihiilini; Writers

Dan Crawford (pgs. 8.9.18)

Jay Mangum (pg. 7)

Lynn Wooten (pgs. iO, 11. 26)

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annually by the UNC-Chapel Hill Medical Alumni
Association. Chapel Hill. NC 275 1 4. Postage is paid
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MedicalAlumni

BULLETIN

School of Medicine, University of North Carolina at Chapel Hill

Contents

Features

Cover Stoiy. Genome Science Initiative Puts UNC in the Driver's Seat 2

Genomics 101 : Top Faculty Share Research Insights 4

Nurse Midwives Offer Full Spectrum of Care 6

Snapshots of Special Events 8

Frta//nPrq/f/e: Stiles" Style Makes Mark In Pediatrics 10

UNC-Led Research Gets $15 Million Gift 12

School of Medicine Boasts Its Ow n "Dtxigie Howser" 1 3

Alumni Profile: Ray Mitchell. MD "73: He"s Got the Beat 14

Alan Briggaman. MD Is A Winner No Matter How You See It 1 S

UNC Tests New Liver Dialysis Device 19

Diabetes Treatments Undergo Quiet Revolution 22

Student Research Day 23

Scientists Bypass Major Hurdle to Aid Hemophilia 24

2001 Dean's Receptions 26

Departments

Dean's Page Inside Front Cover

Faculty Notes 9

Research Briefs 16

News Briefs 20

Development Notes -^

.Alumni Notes 27

President's Ixttcr Inside Back Cover

CMF/Alumni Calendar Back ("over

<)i\ ihc Ciivci: Willi the hiiimin ficminic now mapped. DNA is more iiupuruini iluiii ever in lln
tiiliirc nfmctlicdl ir\c<inh. I '\'Chiipc\ to Icail ihc u i/\.

Genome Science Initiative I

A public-private investment in a
campuswide genome sciences ini-
tiative representing at least $245
million over the next decade
places the University of North Carolina at
Chapel Hill in the driver's seat of this breath-
taking revolution.

That commitment, which includes a $25
million anonymous gift, places UNC at the
forefront of discovery in this rapidly emerg-
ing scientific field, said Chancellor James
Moeser at the February announcement.

"We aim to do our part in leading this
breathtaking revolution spurred by DNA and
the book of life," he said. "Carolina will be a
driving force in determining how the ge-
nomics revolution will change the way in
which we treat human diseases, design drugs
and grow crops."

University leaders, representing diverse
academic areas, are making strategic support
of the UNC genome sciences a top priority
and are investing the resources necessary to
position UNC for leadership among major
research universities.

Quick Progress in Building a
Genomics Program

A strategic pursuit of state and federal
funding, coupled with strong support from
North Carolina taxpayers and private donors,
has further fortified quick progress in build-
ing a genomics program. A few examples
follow:

New buildings: Four new buildings that
will house genomics research are supported
in part by the historic bond referendum ap-
proved by North Carolina voters last fall. The
Medical Biomolecular Research Building, a
$64-million project, will receive S34 million
in bond money and prior state appropria-
tions: the Science Complex, estimated to be a
$400-million-plus project, will receive $88
million in bond money toward its first two
phases; the Bioinfomiatics Building, a $30-.
million project, will receive $2 million in
bond money: and the Research and Teaching
Building, a $39-million project, will receive
S13 million in bond money. Portions of these
buildings will be used for genomics and re-
lated research.

Campuswide strategic support: The
university has committed more than $50 mil-

Tlie new Bioinfonnatics Building u/// encompass 150.000 square feet over six floors. The projected construction completion date is
December 2002.

its UNC in the Driver's Seat

lion in recurring funds for 40 new faculty po-
sitions associated u ith genomics, through
carefully considered reallocation of existing
funds or generation of new funds for this sci-
entific initiati\e. This support also includes
start-up costs and iaborator> equipment.

The Michael Hooker Center for
Proteomics: An anonsmous S25 million gift
u as made to the School of Medicine that
supports research in a promising area of spe-
cialization in genetics that catalogs the pro-
teins expressed in cells — crucial to the
potential of the Human Genome Project.
Michael Hooker. UNC chancellor from 1995
until his death in June 1999. was a strong ad-
vocate for science and technology initiatives
at UNC. In 1999. an anonymous gift created
a SI million endowed professorship in biolo-
gy with a focus in genomics to honor him.

New federal appropriation: The N.C.
Congressional delegation, including Sen.
Jesse Helms and Rep. Da\ id Price, secured a
new S2.25 million appropriation under the
U.S. Department of Health and Human Ser-
vices budget. The appropriation v\ ill fund
program and infrastructure support including
laboratory' equipment.

A Timely Initiative

School of Medicine Dean Jeffrey L.
Houpt. MD. said the genome sciences initia-
tive is especially timely, as scientists are
making remarkable disco\eries about the
role of proteins in unraveling the mysteries of
DNA and the human genome.

Genomics in\ olves the study of the se-
quence of DNA. u hich is the genetic materi-
al of living organisms. Knowledge of genes
and their role in human disease may ulti-
mately pro\e instrumental in cures for a wide
variety of diseases. Inlemaiionally renowned
scientists, including Francis Collins. MD. di-
rector of the National Human Genome Re-
search Institute and a UNC medical school
graduate, announced Feb. 1 2 the first "map"
of the human genome.

"One of the major disctneries that came
out of this recent announcemenl was just
how instrumental the proteins are in the
processes that keep the bods healthy, as well

as the factors that result in disease."" Houpt
said. ""The fact that we already ha\e received
a $25 million gift devoted solely to the study
of proteins brings an added sense of excite-
ment to our genomics initiative.""

Last summer. UNC recruited Terry R.
Magnuson. MD. from Case Western Resene
University as founding chairman of the de-
partment of genetics. (A profile of Magnuson
appeared in the summer 2000 issue of the
Medical Alumni Bulletin.) Magnuson
brought with him his entire 15-member labo-
ratory group - and 10.000 mice for mouse
genefics research.

In his first six months on the job.
Magnuson hired seven of the top assistant
professors in the field, including three from
prestigious posts in England. He also orga-
nized the campusvv ide center for genome sci-
ences, called the Carolina Center for
Genome Sciences. Both the department of
genetics and the center are in the School of
Medicine but extend to other parts of the uni-
versity.

An Investment in Patient
Care, Disease Treatment

The UNC budget committee, the Provost"s
strategic initiative and other university
sources have allocated S7..^ million this year
alone in start-up funds for genome sciences.

UNC received two prestigious grants in
1999, which added momentum to its efforts
to become a leader in genomics research.
The Howard Hughes Medical Institute gave
the School of Medicine S2.6 million, distrib-
uted over fi)ur years, to develop and stall a
new genetics center And the National Insti-
tutes of Health selected L'NC as one of two
Regional Mutant Mouse Resource Centers in
the nation, a grant of S5 million over five
years.

In addition, the North Carolina Biotech-
nology Center has invested more than
S4(K). (KK) in UNC"s genomics initiatives, in-
cluding funds to help recaiit Magnuson. TTie
university's efforts will benefit the state's
economy as research finds application in
medical and business areas. And it will pre-

sent opportunities to collaborate on research
with other state campuses.

North Carolina voters played an important
role in UNC"s genomics "blueprint."" approv-
ing November's bond referendum allocating
$3.1 billion to UNC campuses and N.C.
communitv colleges fiir repair, renov ation
and construction of classrooms, laboratories
and other buildings. UNC-Chapel HilKs por-
tion of the bond package is about
$499 million.

Houpt said genomics w ill transform the
field of modem medicine, and that the pres-
ence of one of the nation"s top teaching hos-
pitals. UNC Hospitals, will enhance
opportunities for collaboration to take re-
search findings from the laboratory to the
clinical setting — and. ultimately, to patients.

Collaboration and
Training for the Future

Magnuson said a teaching component is
critical to UNC"s promise of becoming a
leader in this emerging science. UNC"s de-
partment of genetics is establishing a human
genetics minor and. in conjunction w ith the
clinical departments, just accepted its first
medical genetics resident.

"We have an obligation to train the next
generations of medical researchers to fulfill
the promise of this field, and our cam-
pusvv ide collaboration will ensure that these
budding researchers have the breadth
of know ledge that encourages discov erv. '"
Maiinuson said.

Genomics 101: Top Facil

Editor's Note: In February, a special brief-
ing by several facii I r\- leading UNC's efforts
in genome science was held at the Lineberger
Comprehensive Cancer Center They ad-
dressed the implications of genomics in areas
ranging from cancer to cystic fibrosis to biol-
ogy. It was attended by news reporters, col-
leagues, and members of the UNC Board of
Trustees. Here are excerpts from the briefing.

Terry Magnuson, PhD, Sarah
Graham Kenan Professor

Magnuson, founding chair of the depart-
ment of genetics, is organizing a campuswide
center for
genome sci-
ences. Mag-
nuson is one
of the
world's most
sought-after
experts in
mammalian
genetics. His
research fo-
cuses on ge-
nomics and
mammalian
developmen-
tal genetics.

Magnuson

The Challenge of the
Post-Genome Era

With the development of new data on gene
sequence, along with emerging novel tech-
nologies, the global biomedical research en-
terprise is undergoing a major paradigm shift
that is revolutionizing biological research.
Hypothesis-driven science has been the his-
torical modus operandi for the last 200 years.
However, because of the current exponential
increase in genomic data, a shift to discov-
ery-driven science is under way. This change
will form the basis for new, more intelligent
hypotheses, which will serve as the founda-
tion for new, targeted treatments for many
diseases. Furthemiore, preventive medicine
will nourish with the identification of indi-
vidual predisposition to specific diseases and
a much deeper understanding of basic bio-
logical phenomena.

The immense quantity of data being gen-
erated is just the beginning of this revolution.
The next great challenge is now upon us: to
provide meaning to this vast catalog of infor-
mation, a challenge orders-of-magnitude
more difficult than we have previously faced.
Knowing which gene networks are not func-
tioning properly, or which genetic variants
influence disease predisposition in an organ-
ism, contributes significantly to the ability to
develop effective clinical interventions for
any particular disease.

A basic research program in genetics and
genomics within the context of a major uni-
versity such as UNC represents an exciting
paradigm for bench-to-bedside research. The
research approaches being applied range
from large-scale genome sequencing to the
micro-scale assaying of the metabolic state of
a single cell. However, all approaches share
the theme of integrating biology with tech-
nology and maximize the use of computa-
tional data analysis and management.

The application of the tools of genetics/ge-
nomics will have a profound impact on scien-
tific discovery, the delivery of health care, the
legal system and on many aspects of our cul-
ture and society. As a result, these technolo-
gies and their scientific uses demand
integration with the ethical, legal, social and
technology transfer programs.

H. Shelton Earp III, MD '70

Earp is director of the UNC Lineberger
Comprehensive Cancer Center. His laborato-
ry conducts basic research on the behavior of
cancer cells, studying signals that regulate
growth.

Earp

investigator on four grants.

Research in Cancer Genetics:
Toward Improved Cancer
Prevention & Treatment

Some gene mutations are carried by the
germ cells, sperm or egg, from parent to
child: these can result in inherited illnesses.
Mutations, both spontaneous or caused by
environmental exposure, also occur in the
body's other cells during the course of our
everyday existence. These single mutations
in our non-germ cells are often harmless and
the cell simply dies. Mutations in growth reg-
ulatory genes, however, can start a cell down
the path to cancer.

Fortunately, the body still has many lines
of defense left, and most clinically apparent
cancers can only be established when the
original cell continues to divide and picks up
four to six additional mutations over the
course of 10 to 20 years. Molecular ap-
proaches have allowed identification of some
key mutations that initiate cancer progres-
sion; however, sequencing of the human
genome is a watershed event that will lead
eventually to a fuller understanding of the re-
lation between genes and cancer.

One large project undertaken by a team of
investigators is defining cancer susceptibility.

We know that certain families exhibit a
high risk of cancer because they carry a mu-
tated gene and pass it from generation to gen-
eration. While these familial cancer
syndromes constitute only between 5 percent
and 10 percent of cancers, identification of
the involved genes has been enormously in-
structive. Most of these familial cancer genes
function in control of DNA replication or
proofreading and repair of damaged DNA.
These are the cell's fail-safe mechanisms that
prevent mutations and allow pertection in the
passage of our DNA to daughter cells. When
the capacity to police DNA imperfections is
compromised, many more mutations occur,
making cancer-causing mutations all the
more likely. One hypothesis of our cancer ge-
netics effort is that the other 90 percent of
cancers do not arise spontaneously in an
equally susceptible population. Rather, we
believe that individuals or families vary in
cancer susceptibility because they inherit a

ty Share Research Insights

complex set of gene alterations — each one
of which, by itself, is insufficient to increase
susceptibility, but the constellation, when in-
herited together, increases cancer risk.

Richard Boucher, MD,
William Rand Kenan
Professor, Department
of Medicine

Boucher has directed the Division of Pul-
monary and Critical Care Medicine, Depart-
ment of Medicine, since 1 990 and the Cystic
Fibrosis/Pul-
monary Re-
search and
Treatment
Center since
1988. He is
co-director of
the UNC Gene
Therapy Cen-
ter In 1 992, he
helped devel-
op a gene
"knockout"
mouse model
for cystic fi-
brosis.

BoHclnr

Proteomics and New
Therapies for Cystic Fibrosis

The genomics revolution has afforded un-
paralleled opportunities to understand in de-
tail the pathogenesis of human diseases and
design and implement honcI. rc\()lutionar\
therapies. Ho\\e\er. the genomics revolution
requires that a sequence of "follow-on" tech-
nologies be developed.

As one example, it is important to under-
stand the nature of the structure and function
of the proteins that ha\e been/will be identi-
fied as a function of the genomics revolution
and, most importantly, to understand how
they I'unction in the context of living organ-
isms. Tlie Held of "proteomics" consequently
has e\i)l\ed to pro\ ide investigators world-
wide the capacity to measure the level of pro-
teins expressed in individual human cells
and. most importantly, understand how they
interact with other proteins to perlbrm nor-

mal cellular functions, and how they may
function abnomially in disease processes.

Such knowledge is critical for developing
no\ el therapies for the major lethal disease of
white children in the United States, cystic fi-
brosis. In cystic fibrosis, the affected cells of
the lung exhibit abnonnalities that reflect the
absence of the CF protein's (known as
CFTR) function itself, and also the absence
of important interactions with other cellular
proteins. The identification of these interac-
tions is key to developing therapies to "take
up the slack" for missing CFTR-"other" cell
protein interactions that are important for
cell, organ-level and patient health.

Jeff Dangl, PhD, John N.
Couch Professor of Biology

Dangl is a member of the curriculum in
genetics at UNC. He received bachelor's
degrees in biology and modern literature
from Stanford in 1980. His doctoral work
was in the genetics department at Stanford.
Research in the Dangl lab is funded by the
National Institutes of Health, the NSF. the
U.S. Department of Energ). the U.S. Depart-
ment of Agriculture and Syngenta. The
Dangl lab collaborates with Syngenta re-
searchers to understand how plants respond
to pathogens, with the aim of engineering
plants that can resist infection with less
chemical input.

Romancing the Wild
Mustard: Arabidopsis
thaliana

During the week of Dec. 10. 1999. an ni-
temational consortium announced that it had
completed the first genome sequence of a
higher plant. This small weed. Arabidopsis
thaliana. according to a report in Science.
could offer a w indow into the genetic make-
up of all plants, including important crops.
One scientist predicted that the genome se-
quence might lead to the development ot
crops better suited to developing countries,
plants designed to soak up more carbon diox-
ide and other applications yet to be imagined.

The genome sequence produced by the
consortium of six international sequencing

teams on three continents pulled off a small
coup. The sequence produced was more ac-
curate than that of any multi-cellular organ-
ism published previously. Plants, it appears,
might be inuch more complex than many bi-
ologists have imagined. Arabidopsis. it
seems, has some 2."^. 000 genes, compared
with 1.^.600 in the fruit An and an estimated
30,000 in humans. Moreover. Arabidopsis
has homologues of many important human
proteins involved in disease and cancer.
Among these 100 disease-causing counter-
parts in huinans are the genes involved in
cystic fibrosis and breast cancer. Still, we
have a long way to go: Nearly half of all Ara-
bidopsis genes hav e unknovv n functions.

The National Science Foundation 2010
Project, a 1 0-year effort by the plant biology
community, envisions that in a decade every
gene in Arabidopsis w ill have been subjected
to one or more experiments in vv hich the gene
is inactivated or over-expressed. The result-
ing phenotypes then will be examined bv all
available criteria. Gene-expressed proteins
will be localized and comprehensive infor-
mation made available as to how they are
modified and, perhaps, interact. □

Nurse Midwives Ofife

By Eleanor Yates

Danielle Bowen wanted the birth of
her child to be as simple and nat-
ural as possible. She had her own
ideas about the delivery, and even
drew up her own birth plan. But Bowen also
liked the idea of having immediate access to
skilled medical care should she need it.

She got the best of both worlds through
the nurse-midwifery services offered
through the School of Medicine's Depart-
ment of Obstetrics and Gynecology, the only
hospital-based midwifery program in the
Triangle area.

Kathy Higgins. a certified nurse midwife.
is director of the midwifery service at UNC.
Besides providing extensive education and
compassionate support to pregnant women.
Higgins offers a variety of gynecologic care
and support to women of all ages.

"I spend a lot of time with our patients, be-
cause I want them to make educated, in-
formed choices."" said Higgins. "I ask women
what they want from the birthing experience.
It"s very family-centered care.""

Higgins. who holds a master"s of science
degree from Georgetown University, served
as a nurse, nurse-midwife and commander in
the U.S. Air Force for many years. Among
her career achievements was receiving the
Bronze Star, awarded for her leadership
under fire during Operation Desert
Shield/Storm in 1 99 1 . She joined the UNC
faculty to launch the midwifery service fol-
lowing her retirement from the military.

Although many people think midwives
practice in people's homes, most of today"s
skilled certified nurse midwives practice
within a variety of health care settings. Certi-
fied nurse midwives are delivering an in-
creasing number of babies in the United
States, currently about 7 percent of the births,
compared to 1 percent just 10 years ago.
There are about 7.000 certified nurse mid-
wives in the country.

Certified nurse midwives are registered
nurses who have undergone additional edu-
cation and training in midwifery. They must

6

pass a board examination given by the Amer-
ican College of Nurse Midwives Certifica-
tion Council Inc. before they can practice
health care.

Midwifery has a long, rich heritage. Hip-
pocrates started the first documented, formal
midwifery training program in the 5th centu-
ry B.C. During colonial times in the United
States, midwives were responsible for the
care of pregnant women and. in the absence
of physicians, often were the only health-
care providers for people in a community.

"The word "midwife" means 'with
woman," and that's exactly how they support
pregnancy.'" said Valerie Parisi, MD. chair of
the department of obstetrics and gynecology.
"Midwifery care is ideal for low-risk women
who want a "low tech-high touch' birthing
experience offered within the safety of a hos-
pital environment.""

The department of obstetrics and gynecol-
ogy began offering nurse midwifery ser\'ices
in 1999. The department of family practice
also employs a nurse-midwife.

Currently, about 60 percent of the mid-
wives' patients are pregnant. Other patients
are seen for well-woman gynecologic care,
including such things as annual physical
exams, contraceptive counseling, preconcep-
tion care, perimenopause and menopause
management, and gynecologic infection
treatment.

Certified nurse midwives see women who
are basically healthy. Women with no med-
ical problems and who have nonnal pregnan-
cies are good candidates for nurse-midwifery
care. Women with high-risk complications

— such as bleedi ng disorders or heart trouble
or who are pregnant with more than one baby

— require care from an obstetrician.

In some cases, nurse-midwives will co-
manage pregnancies with a physician. For
example, a pregnant woman with stable dia-
betes can see a midwife and physician to-
gether, and be delivered by the midwife if no
complications develop.

Early in a woman's pregnancy, Higgins
spends time discussing issues such as breast-

feeding and bonding with the baby, and be-
lieves it is crucial for patients to actively pre-
pare for birth.

"In fact. I tell patients I'm not going to de-
liver the baby — they are." she said, smiling.

When delivery time draws near. Higgins
keeps in constant contact with the mothers-
to-be. If she foresees any problems, she con-
sults with physicians.

Once a woman comes to the hospital for
delivery. Higgins interacts frequently with
her. Babies are bom in the birthing rooms in
the labor and delivery suite at UNC Hospi-
tals. Higgins remains with her patient
throughout labor and delivery, offering help
and moral support, comfort measures and
guidance throughout the entire birthing ex-
perience.

A nurse-midwife will maintain that an im-
portant part of her role is to advocate for pa-
tients. especially during challenging
circumstances. Higgins described one situa-
tion in which a new mother wanted to breast-
feed her premature infant while the baby was
hospitalized in the neonatal intensive care
unit. Higgins arranged for that to happen.

Bowen. who gave birth to her son. Gavin,
last July, wanted to remain up-and-about as
much as possible during her labor. She did
not want an IV. an epidural or an episiotomy.
and she wanted to hold her baby seconds
after he was bom.

As it turned out. Bowen was in labor for
26 hours, including 1 2 hours at the hospital.

"Kathy was very encouraging. She kept
me in control." Bowen said. "She is very
good at letting you push the limit, but know-
ing when to medically step in. You get the
delivery you want, but your health and your
baby's health come first.""

UNC"s nurse-midwi\'es see patients dur-
ing regular clinic hours at Chapel Hill North
Medical Center and the UNC Ambulatory
Care Center. One recent afternoon, Higgins
met with a young woman who had never un-
dergone a gynecologic exam.

"During these first exams, you really need
to establish the tiust factor," Higgins said.

Some patients have menstrual problems.

Full Spectrum of Care

Kcithy Higgins. CNW. far left, chats with Mary Bclh unci Steven Brakcr nhinit pUmning
for a Ixihy.

Others want to discuss birth conlri)!. Some-
times patients are so anxious that Higgins
spends the entire appointment just talking
and listening, asking them to return lor the
exam.

That same afternoon, another patient ar-
rived for a six-week postpartum check-up.
This patient, like many, brought along her
new baby for "shov. and tell." Higgins \<.as
delighted to see the baby, but had plenty of
questions for .Viom.

"How are you adjusting to the baby'.'"'

"How arc the feedings going'.'"

"What do vou want to do about birth con-
trol?"

About 10 percent of new mothers suffer
from postpartum depression, and certified
nurse midwives make sure they understand
symptoms of the problem and \\\\cn lo seek
help.

Clinic time also means re\ levying lab re-
sults, checking pap smears or th\r()id test re-
sults. While seeing patients in the clinic,

midwives may consult \\ ith a psychologist,
nutritionist or other specialist to help with a
particular need. Midwives regularly ad\ ise
v\ omen w ho w ant to become pregnant to start
taking folic acid supplements and offer pre-
conception counseling to identify and coirect
any existing problems before women be-
come pregnant.

During an appointment with a patient
ncaring menopau.se, Higgins talked about the
many changes a woman's body undergoes al
that time.

"Sometimes you will feel like you're
going crazy," Higgins said. "You'll be more
emotional and wonder \\ hat's the matter with
you. but it's all nomial."

Assuring her patient that menopause
doesn't mean suffering. Higgins discussed
hormone replacement therapies, incluiling
natural and drug therapies, and emphasized
the importance of exercise, \itamins and cal-
cium. Because patients ncaring menopause
can become pregnant, Higgins also discussed

birth-control methods.

When another patient visited the clinic
after suffering several miscarriages. Higgins
referred her to a physician to determine pos-
sible causes and a plan for conception.

Aimee Lehmann. w ho returned to the clin-
ic for a six-week postpartum check-up, re-
membered being surprised that a certified
nurse midwife was a\ailable through UNC
Health Care.

"I wanted the least clinical birth as possi-
ble." she said. "I really think with midwives
the experience is more patient- and family-
centered. And I like the fact that you ha\e a
say in the process.'"

Lehmann also appreciated the continuity
of care.

"Froin day one, I knew who w as going lo
deliver my baby,"" she said, adding that she
was grateful to have a certified nurse mid-
\\ ife in her room throughout her labor

During her pregnane), Lehmann learned
she had a blood clotting disorder. Her certi-
fied nurse midw ife worked closely w ith an
obstetrician during her labor, and arranged
for her to see a hematologist shortly after de-
li\ery.

Higgins helped Mary Beth Braker delixer
her daughter, Annie. For eight months. Bnik-
er saw a traditional obstetrician.

"Our ideas for birth and the doctor's ideas
were very different," Brakcr explained. "We
really wanted a natural birth, and it looked
like it would be hard to get that."

Brakcr then saw a pamphlet about UNC's
Nurse Midw ifery Services.

"Going w ilh a ccrtitled nurse midwife v\as
a huge relief." she said. "It's a different ap-
proach. Birth is a natural process and the
body know s w hat to do. Kalhy was there to
facilitate the birth, but not to intervene iin-
necessarilv."

Snapshots of Special Events

Family Gathering. . .

Honohng the contiihiitions of "Walter Reeee BenyhilL MD. upon the anniversaiy of his
100th birth was truly a family affair. Norma Benyhill, wife of the late Berryhill. and family
members were all smiles thtriiii; the festivities which coincided with the annual Norma
Benyhill Distinguished Lectureship. This year 's speaker was George Sheldon. MD, Zack
D. Owens distinguished professor ofsiirgeiy and chair of the department of surgery.

Dance The Night Away!

More than 400 UNC students did just
that Feb. 23 to raise oney for pediatric
programs at the N.C. Children 's
Hospital. The Dance Marathon raised
over $100,200 — a record in the
event's three-year histoiy. The event is
organized solely by students.

2000 Nursing Recognition Awards...

Six outstanding nurses were recognized at the School
of Medicine 's biannual medical staff meeting by Dean
Jeffrey L Houpt, MD. and Stanley R. Mandel, MD,
chief of stajf. The awards, established in 1992, are
designed to recognize outstanding achievement by
mn sing professionals. Honorees — who receive $1,000
to be applied toward professional development — are
cho.sen based on their excellence in inirsing practice,
evidence of special qualities of caring and compassion,
and commimwnt to teaching future health care
professionals.

Winners are back row, from left, Houpt, Lynn
Farber, pediatric surgeiy nurse clinician: Maria
Vaslef neurosurgery intensive care unit: Benjamin
Butler specializing in pediatric pulmonology:
Front row, from left, Kate Little, supeiTisor of
radiological nurses in the departnwnt of radiology;
Clara Neyhart, nurse clinicicm in nephrology and
hypertension: and Loree Farber, nurse education
clinician, N.C. Jaxcee Burn Center and Maiuiel.

Faculty
Notes

Timothy S. Carey, MD. professor of medi-
cine and epideiniolo-

Can'\

gy. has been named
director of the Cecil
G. Sheps Center for
Health Services Re-
search. Carey re-
places Gordon H.
DeFriese. who ser\ed
as the center's director
since 1973.
A Sheps Center se-

nior fellow and Carolina faculty member
since 1986. Carey is interested in e\idence-
based medicine, access to care, and medical
outcomes.

Se\'eral of his current research projects ex-
amine technology assessment, including the
benefits and disadvantages of tube feedings
for frail, elderly individuals. He is studying
racial disparities in health for black adults,
particularly in rural settings, and has con-
ducted a number of studies to examine the
outcomes of care for low back pain.

He is co-director of the joint Research Tri-
angle Institute/UNC Evidence-Based Prac-
tice Center examining the strength of the
literature on a variety of topics. Carey is cur-
rentls the deputy director of the UNC Pro-
gram on Health Outcomes.

The Sheps Center is one of the nation's
oldest and largest health services research
centers, encompassing an interdisciplinary
program of research, consultation, technical
assistance and training, focusing on the ac-
cessibility, adequacy, organization, cost and
effectiveness of health care services.

Richard Clark, MD. professor of radiology,
recently received a NIH-NIDDK contract to
participate in a three-year multi-institutional
study of analgesic nephropathy. He will be
coordinating the CT e\aluation of patients
with this chronic renal disease with the goal
of de\eloping reliable CT screening criteria
for its diagnosis. Assisting him in this project
are Da\id Warshauer. Ml). Wend\ Hayes.
DO and research assistant Kathy Wilber. RT.

Tamera Coyne-Bea.slcv, MI), MPH. assis-
tant professor of pediatrics and internal med-
icine recently received a grant of SftO.OOO
annuall) for tne years from the William T.
Grant F-oundation through the Faculty Schol-
ars Program. She was a Uni\ersity nominee
for this international competition and is the
first l^NC phssician to recei\e this avvard.
The award will support her research on

Welcome Aboard! Sclwol of Medicine Dean Jeffrey L Hoiipl. MD. and
f'aciilrx welcomed new department chairs during a reception held in their h(mor kist
November Standing left to right are Travis Meredith. MD. department of
ophthalmology: Marschall Riingee. MD. department of medicine: Alan Stiles. MD.
department of pediatrics: Uniis Diaz. MD. department of dermatology: Lee
McLean. PhD. department of allied health: Terry Magnnson. PhD. department
of genetics, and Houpt.

Coxne-Beaslex

strategies utilizing
youth to reduce
firearm injuries
among children and
adolescents. She also
received a four-year
grant from the Robert
Wood Johnson Foun-
dation through the
Minority Medical
Faculty Development
Program. This grant will support her re-
search on the effecti\eness of tlreami safety
counseling and safe storage.

Cherri Hobgood, MD. clinical assistant
professor, department of emergency medi-
cine, and director of undergraduate medical
education has won the Robert Doheriy teach-
ing fellowship scholarship, presented by the
Emergency Medicine Residents" Associa-
tion. The scholarship is designetl lor junior
faculty members
who show outstand-
ing promise as
emergency medi-
cine educators and
who display a com-
mitment to einer-
gency medicine
residents and medi-
al students seeking
careers in the field.

Mitchell

H<lhg<HHl

Beverly S. Mitchell, MD. chief of the divi-
sion of hematology/oncology and associate
director of the UNC Lineberger Comprehen-
sive Cancer Center, has been named presi-
dent of the American Society of
Hematology. Mitchell is also the Wellcome
distinguished professor of cancer research.
Her research interests center around the ways
to make leukemic cells more sensiti\e to

treatment. Among her honors are the Jerome
W. Conn Award for Excellence in Reseiuch.
the Leukemia Soci-
ety of America
Stohlman Award
and the H. Marvin
Pollard Award for
Outstanding Resi-
dent Teaching. She
also ser\'ed on sev-
eral editorial
boards, including
the Journal of Clini-
cian Investigation
and on advisory boiu-ds to the National Can-
cer Institute, and the Leukemia and Lym-
phoma Society. The society promotes
scientific and educational endeavors related
to blood and blood-forming tissues, as well
as encourages hematological investigations.

Pascal Osi Udekwu, MD. assistant profes-
sor of surgei^. Wake AHFC. was selected for
membership in the American .Association for
the SurgeiT of Trauma. He recentls received
the Harry F. Dascomb. MD. Award tor \:\-
cellence in Clinical Teaching and Care
which was presented at the Graduate Med-
ical Fducati(Mi Recognition Dinner.

Ktta Pisantt, MD. professor of radiology,
has been elected secretarv -treasurer of the
.Association of University of Radiologists.
She recently was appointed to the editorial
board of the Journal of Women's Imaging
and chaired a scientific panel on Breast
Imaging at the Association of University Ra-
iliolouisls annual meetini;.

Faculty Profile

Stiles' Style Makes

By Lynn Wooten

In a roundabout way, Alan D. Stiles, MD,
credits his career in pediatrics to scuba
diving.

The new chair of the Department of Pedi-
atrics. Stiles grew up in Canton, N.C., an area
rife with lakes — and, unfortunately, plenty
of drownings and swimming accidents to
keep the rescue squad there busy. Because
Stiles" father was a member of the squad,
young Alan often witnessed its members in
action - including the time a diver taught res-
cuers about scuba to aid their efforts in recov-
ering the bodies of drowning victims.

"1 was fairly adventurous," Stiles remem-
bered. "For someone in a small town, I had a
great series of opportunities come up, such as
scuba."

When he was about 10 years old. Stiles
suited up with his dad and other rescuers and
learned scuba diving. The experience un-
leashed an interest in marine biology and ma-
rine archaeology that led to diving jaunts in
the Caribbean, stints as a part-time lifeguard
with the YMC A and a youth camp counselor.
The camp job, in particular, sparked a notion
he had not yet considered: "You know, I
wanted to have people in what I do." Ac-
knowledging a long-recognized bent toward
science. Stiles pondered a career in medicine.
"This sort of brought it all together for me."

Stiles, a UNC undergraduate, applied to
medical school on the "very last possible day
you could." As he awaited word on whether
he would enter the UNC School of Medicine
— he was on the waiting list — he worked as
an assistant in a UNC lab, basically washing
dishes and doing other chores. He also mar-
ried his high school sweetheart, Brenda.

Around 8:30 p.m. the evening before the
next semester began, he heard from a mentor.
William D. Heizer, MD, professor of medi-
cine and nutrition. "I've been trying to track
you down for two days." Heizer told him,
adding that Stiles had made it into med
school.

"After a few hasty phone calls, he was lo-
cated and told the news, which seemed to
please him considerably," Heizer recalled.
"The fact that a person of his talent was al-

10

most not admitted to
this medical school is
just another indication
of how difficult and
humbling the job of
medical school admis-
sions is."

Stiles reported to his
first day of class the
next morning.

"I've never looked
back at that since,"
Stiles said, 24 years
after obtaining his MD
at UNC, sitting in his
office as the chair of
UNC's Department of
Pediatrics. His climb to
this position was a long
journey.

After medical school
graduation. Stiles was a
resident — then chief
resident — in UNC's
pediatrics department
and remained at the
University before going
to Harvard Medical
School to participate in
the joint program in
neonatology, its neona-
tal-perinatal program.
A rotation in neonatol-
ogy as a student at
Wake Hospital in
Raleigh was a good fit,
as well. "I felt like I had Alan D. Stiles. MD
walked into home," he
said.

Stiles returned to UNC in 1986 as an assis-
tant professor in pediatrics.

"I really thought in medical school that 1
would become an internist," Stiles said. "But
I found that I liked the people and the chil-
dren and dealing with families and having a
very serious public health impact by chang-
ing behaviors at such early stages. I also liked
that pediatrics was very academic in nature."

His ascendancy to pediatrics chair last
year was "unexpected," Stiles said. "It was
not something I would have imagined at this

77

point in my life."

Others, though, said it was an easy choice.

"He is always approachable — by phone,
in person or before or after meetings, even
those into the evening," said Marlene Rifkin,
senior vice president and administrator of the
N.C. Women's and Children's hospitals. "He
listens, he counsels and he empathizes. He is
a true leader for Children's, and we're de-
lighted to have him at the helm."

Jacob Lohr, MD, vice chair of pediatrics,
cited a number of Stiles' attributes. "He is
keenly aware of the financial challenges fac-

Mark in Pediatrics

ing an academic department of pediatrics in
the new millennium, and he is an unusually
adept financial manager. These challenges
have not diminished in his mind the impor-
tance of the department's basic academic
missions."

Laboratory-based research has been a
major part of Stiles" career. During his year
as chief resident in pediatrics. Stiles worked
with Joseph D'Ercole. MD. a member of the
Pediatric Endocrine group at UNC. and
began a career long interest in growth factors,
small proteins that are acti\ e in signaling
cells todi\ ide and grow. During his neonatol-
ogy fellowship at Harvard. Stiles was one of
the first investigators to examine growth fac-
tors during fetal lung de\ elopment.

Stiles has remained focused on questions
related to lung grov\th and controls of cell di-
\ ision since because both are areas important
to fetal and newborn health. He is strongly
committed to research in pediatrics as a basic
part of his new position. Although he doesn't

ha\e the same opportunity to personalh'
work in the laboratory as before, he said. ""I
have inherited a faculty w ho are leaders in
child health related research. Sustaining and
fostering the research of the faculty and
working toward establishing new faculty as
successful investigators is one of my highest
priorities."

Stiles has clear thoughts on the department
now and how he sees it de\eloping. "Pedi-
atrics has always seen its mission as being a
department that values its residents and train-
ing excellent generalist pediatricians. Most
everything flows from there. Its second
strength is its strong faculty. That's a legacy
that I inherited here."

Stiles sees unlimited potential in the new
N.C. Children's Hospital, w hich opens later
this year. For the first time. LINC will have its
pediatrics offerings con\ eniently located
under one roof.

"It has been horribly disjointed." Stiles
said. "My idea is "seamless' for the kind of

care that people get here if we do this right. I
think we will use the springboard of the new
facility to deal with \'ery sick children and
care for some subspecialty needs they ha\ e."

Lohr said he has noted Stiles' emphasis on
this. "He understands the necessary balance
between our tertiary level subspecialty clini-
cal services and our hospital-ba.sed and com-
munity-based general pediatrics activities,"
Lohr said. Plus, he appreciates the necessity
for family-based CMe in all these settings."

Within five ye;irs. Stiles predicted, the new
Children's Hospital "will make us the site in
children's health care needs across the state.
And it will raise our profile nationally as a
clinical facility — v\e don't ha\e that nation-
al recosinition vet. But I think we w ill." l_j

Alan Stiles. MI)

Chilli:

Dcpiiniiicut (<t Fcclidirics

Age:

47

Wife:

Brenda

Children:

Justin. 24, now completing

his master's in accountin'j

at Appalachian State

Universitv: and Adam. 1 (\

a junior at Chapel Hill Hiiili

School

KduciUion

B.A.inChemisti-vand

Zooloev. UNC. 1974;

\Ln..l'NC. 1977

5/;7('.s examines an infant in the NICU diiriiii; miiiuls

Bill & Melinda Gates Foundation

UNC-led Research
Gets $15 Million Gift

The Bill & Melinda Gates Founda-
tion has awarded $15. 11 million to
an international consortium of re-
searchers, led by a UNC School of
Medicine professor, to develop new drugs to
fight African sleeping sickness and leishma-
niasis — two diseases that are killing and in-
fecting millions of people in developing
nations.

The five-year grant brings together some
of the world's top experts in drug develop-
ment and delivery to target two common par-
asitic diseases: African trypanosomiasis, or
sleeping sickness, and leishmaniasis.

Richard R. Tidwell, PhD, a professor in
both the schools of medicine and phamiacy,
is principal investigator for the project, which
involves a consortium of more than a dozen
faculty and scientists from Carolina, Georgia
State University, the London School of Hy-
giene and Tropical Medicine, Ohio State
University, the Swiss Tropical Institute, the
Kenya Trypanosomiasis Research Institute
and Immtech International, Inc.

"We are proud of the leadership role that
Dr. Tidwell and his colleagues have been se-
lected to play in the international battle
against two insidious diseases that have
caused so much pain, suffering and despair,"
said Chancellor James Moeser. "This gener-
ous grant will enable an impressive array of
collaborators from academia, government
and the private sector to conduct research
that, through the successful development of
new drug therapies, can dramatically im-
prove people's lives."

The grant will fill a critical void in re-
search funding for the two tropical diseases,
Tidwell said.

"Although the pharmaceutical industry
has made efforts to help fight these diseases
by donating drugs and money, it cannot dedi-
cate the research funds or technical resources
necessary to search for new, more effective
dmgs," he said. "In the competitive market-
place, major pharmaceutical companies must
concentrate on high-profile diseases with
more potential for profits. This grant will cre-

ate a world-class academic and scientific
consortium that can do the job."

A key component of the consortium is
Immtech, a Vernon Hills, 111. -based biophar-
maceutical firm that is already conducting
clinical trials and would manufacture and
distribute the new drugs to the affected na-
tions. Tidwell said.

"Trypanosomiasis and leishmaniasis have
a devastating impact on much of the develop-
ing world," said Gordon Perkin, director of
the Global Health Program at the Bill &
Melinda Gates Foundation. "New drugs are
desperately needed and we're optimistic that
this consortium will not only be able to de-
velop them, but will ensure that they are dis-
tributed to those who are infected as quickly
and efficiently as possible."

African sleeping sickness, which is fatal
unless treated, spreads among people bitten
by the tsetse fly. Symptoms begin with a low-
grade fever, pain in the joints and itchy skin.
Eventually, the parasites carrying the disease
enter the brain. Then hallucinations and un-
predictable, disruptive behavior are com-
mon. A victim experiences excruciating pain
and eventually lapses into a coma before
dying.

Leishmaniasis is caused by a parasite that
can live in people, dogs and rodents. Spread
by the bites of tiny sand flies, the disease
causes lesions, severe disfigurement and,
when the parasites invade internal organs,
death. An estimated 12 million people in 88
countries worldwide have the disea.se. Most
cases are reported in developing nations; the
Sudan has been especially hard-hit with a re-
cent outbreak.

The handful of drugs currently available to
treat sleeping sickness has major drawbacks,
including severe toxic side effects that can be
fatal. Evidence also suggests that the disease
is becoming increasingly resistant to melaso-
prol, the most commonly used drug. The few
drugs available to treat leishmaniasis also
produce adverse side effects and require ex-
tended dosage regimens. Drugs used to treat
both diseases must be given by injection - a

major problem in developing nations with se-
verely limited access to health care.

The new grant will extend a decade of
work by Tidwell and his colleagues. In 1990,
their research supported by the National In-
stitutes of Health showed that drugs synthe-
sized to fight AIDS-related infections were
effective against sleeping sickness and leish-
maniasis. The discovery by Tidwell and
David Boykin, PhD, of Georgia State Uni-
versity led to further experiments with a drug
compound called DB 289. That compound
allows medication to be orally absorbed and
converted to an active state through the
body's normal enzyme systems.

The UNC team developed and patented
the compound, which the university has li-
censed to Immtech. The firm already has re-
ceived approval to begin the tlrst phase of
human clinical trials for DB 289 as an anti-
infective drug to treat Pneumocystis carinnii
pneumonia, an opportunistic fungal infection
that is potentially fatal in immune-sup-
pressed patients.

Besides Tidwell, other key UNC team
members are James E. Hall, PhD, associate
professor. School of Pharmacy; Gary Pol-
lack, PhD, professor. School of Pharmacy,
and John R. Seed. PhD, professor. School of
Public Health.

Other consortium members include
W. David Wilson, professor of chemistry at
Georgia State University; Simon Croft, read-
er at the London School of Hygiene and
Tropical Medicine and director of the Worid
Health Organization's Tropical Disease Re-
search Drug Discovery Project; Karl Wer-
bovetz. assistant professor at Ohio State;
Reto Brun, head of protozoology and
chemotherapy, and Christian Burri, head of
the phaiTiiaceutical medicine unit, both of the
Swiss Tropical Institute; as well as J. Mathu
Ndung'u, director of the Kenya Trypanoso-
miasis Research Institute, and Raymond E.
Mdachi. head of that institute's pharmacolo-
gy division. □

12

School of Medicine boasts
its own ''Doogie Howser"

By Katie Macdonald

He's old enough to \ote. but
not old enough to diink. He
can rent a movie, but he'll
ha\ e to wait a few years be-
fore he can rent a car.

At 20. Anup Parikh is the youngest
medical student currently enrolled at
the Uni\ersity"s School of Medicine. A
2000 UNC graduate u ith a bachelor of
science degree in biostatistics from the
School of Public Health. Parikh has
gone straight on to his ne.xt endea\or.
medicine.

"I always wanted to be a doctor." the
first-year medical student said. "It's
what I feel will be most rewarding and
fulfilling de\ oting a life to."

Parikh. who was bom in Charlotte.
NC. is a first-generation American
whose parents mo\ed to the United
States in the late se\ enties from Gujarat.
India, to attend college. When he was
still in grade school, his famil\ mo\ed
to Fort Worth. Texas, but returned to
Wilmington a few years later. Parikh.
w ho w as always a year younger than
most of his classmates because his
birthday fell at the end of the cut-off
time for school enrollment, was able to
skip the seventh grade when his family
moved from Texas back to North Carolina.
The school curriculum was slightly more ad-
vanced in Texas compared to North Carolina,
and Parikh tested above the North Carolina
students.

"Being Nounger has ne\er made me feel
different." insisted Parikh. "It's never been an
issue with my friends or other people. I'm
used to being younger than my classmates
and they are used to me."

Parikh. who served on UNC's Honor
Court as an undergraduate as well as on the
University's Honors Program Advisor)
Board, comes from a long line of physicians.
His uncles on his mother's side are all doc-
tors in the U.S. His grandfather vvas also a

((/) I'arikh

doctor in India, and man\ summers he uoukl
\ isit him and spend time w iih him at his prac-
tice.

"It was fascinating to see him interact u ilh
the patients." said Parikh. w ho enjoss work-
ing with people opposed to working in a lab-
oratory.

One of Parikh's fa\orite experiences m
medical school has been participating in the
AHHC program, which sends students to
rural parts of North Carolina tor a week to
work in a private practice.

"It is such a rewarding experience. " said
Parikh. "DcKtors will let you do patient inier-
\ lews and sometimes even physical exams,
and it really gets you pumped up and moli-
\ated."

Parikh's interests do not all revolve
around medicine, though. For years
he has played the piano and enjoys
singing classical Indian music. Re-
centh. he started learning how to pla>
the harmonium, a type of organ, but
says it's hard to find the time to prac-
tice.

"But it such a great stress relief
when you can finally pla>'." he said.
"It's a nice escape friMii all the study-
ing."

As an undergraduate at 1 6. he com-
pleted his degree in three years w ith-
out attending summer school. Man_\
of his advanced placement courses
from high school transferred tow ard
credit hours at UNC. as did some
college courses he took at UNC-
Wilmington w hile still in high school.
In college. Parikh chose to make
his concentration in public health
rather than major in one of the sci-
ences because he knew he would
e\entuall\ go to medical school,
w here he could focus more on sci-
ence.

"I wanted a ditfereni perspecli\e
that would better prepare me for a fu-
ture in medicine, and I like the collab-
oration between medicine and public
health." said Pankh.

Parikh plans to get his master's in public
health alter his third \ear in medical school.
when he can return to stutl\ing biostatistics
or epidemiologN. Meanwhile, his goal is to
spend this summer in India doing clinical re-
search in cardiologN or ophthalmology, two
medical fields in which he is strongly inter-
ested.

Alumni Profile

Ray Mitchell: He's

By Katie Macdonald

It's early on a Friday afternoon, and
Stephen Ray Mitchell, MD is trying his
best to get out of the office. He's not in a
rush to see patients or attend to any
pressing academic matters. Rather, he's
under a deadline, set by his wife Ellen, to be
home in time for a party they are hosting for
her office.

"My wife works at Inter America Devel-
opment Bank and there is a saying: It's better
to have friends in the marketplace than
money in the bank. We're working on that
preinise." Mitchell said with a chuckle.

Mitchell, Schoolof Medicine class of '73.
has a healthy sense of humor and an enviable
capability to put perspective on his work and
life. He has to. juggling his duties as an adult
and pediatric rheumatologist. an acadeinic
leader and a husband with seven-year-old
twins.

Last June. Georgetown University School
of Medicine appointed Mitchell senior asso-
ciate dean for academic affairs. His new post
follows his seven-year tenure as George-
town's program director in the internal medi-
cine residency program and as the associate
dean for clinical curriculum. Mitchell first
began at Georgetown in the early 1980s after
moving to Washington, D.C. with the United
States Air Force.

Following a four-year medicine-pediatrics
residency and co-chief residency at UNC
Hospitals, Mitchell was commissioned to the
Air Force and assigned to Andrew's Air
Force base and the Unifomied University of
Health Sciences in Washington. While in
D.C. he completed a rheumatology fellow-
ship at Georgetown, where he also discov-
ered a passion for teaching. The academic
medical setting had always intrigued him.
learning under role models at UNC such as
Newton Fisher. MD. Bill Blythe. MD, and
Floyd Denny. MD.

RciY Mitchell. MD

As a physician and teacher at Georgetown,
Mitchell has made his own, indelible mark.
Georgetown's medical school, like UNC's,
carries a long tradition of outstanding faculty.

and Mitchell can count himself among the
top faculty meinbers. After receiving four
Golden Apples, a student-sponsored award
given to a physician faculty member.

14

Got the Beat

Mitchell was retired to the Golden Orchard;
resting place for four-time recipients.
He"s also received housestaff teaching
awards for his regular instruction of clinical
teaching skills.

The former Tar Heel plans to inaugurate
a S2.5 million Faculty De\ elopmcnt Initia-
ti\e this year that will rew ard excellent
teachers, educate young faculty on new aca-
demic approaches and dedicate more time
developing faculty in all the medical disci-
plines. He also takes great pride in leading
the education of a diverse class of students,
including orienting Duke students accepted
to Georgetown's medical program. "I call it
my rehabilitation project." he smiled. (He
still catches grief for having a personalized
Virginia license tag that says. "TAR
HEEL.")

Naturally, his responsibilities and vision-
ary plans make for a busy routine, and there
comes a time when Mitchell needs to un-
wind and let loose. When he does, it is usu-
ally in his 18th century, colonial kitchen in
Alexandria. Va. The kitchen is a special
place to relax, not only because it's rich
with nostalgia and history, but also because
it's w here Mitchell and his family keep their
1947 Wurlit/er jukebox, filled with Caroli-
na beach music. Mitchell bought the juke-
box from an old college friend, who for
years kept it in the waiting room of his
Charlotte. N.C.. orthodontia practice.

"When I bought it. I told my wife it was
not that big and could be tucked away in
some closet." recalled Mitchell. "But it took
four men to get it into the house, and then
we had to leave it in the kitchen, where wc
have brick floors, so it wouldn't damage the
wooden ones."

The jukebox gets a lot ot play, especially
on the weekends w hen friends come over or
when tw ins. Katie and Mac. v\ant to prac-
tice shagging. The tw ins ha\e eclectic taste
in music and have grown up appreciating

dad's love of beach music.

""Miss Grace' by The Thymes is a fa-
vorite song and anything by The Embers."
said Mitchell, who loves to dance w ith his
wife to The Embers' music.

When students or his children's friends
come to the house and see the type of music
Mitchell has chosen for his jukebox, they
assume that beach music is an age-thing
that personifies the difference between
today's youth and the old fogies. But
Mitchell doesn't agree. To him, beach
music is a regional-thing and can be en-
joyed by all ages. Growing up in Shelby.
N.C.. Mitchell always loved beach music,
and spent his summers in Ocean Dri\ e.

Mitchell continued to make his summer
visits while attending UNC. first as an un-
dergraduate, then as a medical student and
finally as a resident in a combined medi-
cine-pediatrics residency. UNC was one of
the first academic medical centers in the
country to offer a combined residency in
those two fields.

Mitchell attributes his interest in pedi-
atrics to his own pediatrician in .Shelby. Paul
Sarazen. MD. a Duke graduate. "But we'll
forgive him for that." joked Mitchell. Some
other role models that influenced him to
consider a combined residency were Larry
Kutchen. MD; Dale Newton. MD. and
George Hemingway. MD. all UNC physi-
cians who did combined training in medi-
cine and pediatrics.

"The combined training gave breadth to
my learning and captured the intensity
of caring for sick adults and children."
said Mitchell.

Now. living contentedly in Alexandria
on. of all streets. Duke Street. Mitchell
talks foiulh of his twelve vears spent in
Chapel Hill.'

"Chapel Hill is a very forgiving place."
he said. "And my experience in medical
school was great. We were \er\ lucky

to have the resources that were offered to us
at UNC."

One place where Mitchell spent many
hours as a medical student, and which he
still considers today to be an excellent en\ i-
ronment for learning, is Berryhill Hall.
"The set-up in there is great for students be-
cause there are small study areas where
smaller groups of students could w ork to-
gether and have a more intimate learning
experience. I would love to have a set-up
like that here at Georgetown."

And when Mitchell is feeling nostalgic
for other fond Carolina memories, he just
turns on his jukebox. "There is a standing
invitation to all Tar Heels. I would love to
see my Chapel Hill friends come through."
he said. Now that they know where to go
and what kind of entertainment to expect,
they are sure to pay a visit.

Research
Briefs

Genetically engineered
enzyme boosts treatment for
rare children's illness

U.S. medical scientists, working together,
have found that a genetically engineered en-
zyme can significantly help children and
young adults with a rare disorder that in-
volves storage of materials within cells, re-
sulting in the cells swelling to the point of
bursting and killing those cells.

In its most severe forni. the disease, mu-
copolysaccharidosis 1. causes progressive
developmental delays, corneal clouding,
lung obstructions, heart disease, severe joint
stiffness and death, usually by age 10. In
milder forms, known as Hurler-Scheie syn-
droine and Scheie syndrome, patients suffer
many of the same medical problems, but they
develop more slowly, and victims die by their
20s or live a nearly normal life span.

A report on the new study of 10 patients
with intermediate disease, which documents
the effectiveness of recoinbinant enzyine
treatments, appears in the Jan. 1 8 issue of the
New Eitglaiul Joiinuil of Medicine. Authors
include Joseph Muenzer, PhD, UNC associ-
ate professor of pediatrics, and 1 6 others.

"We gave patients back an enzyme called
iduronidase that they were missing and that
was made in the laboratory." Muenzer said.
"We saw significant improvement in their
ability to get around, they had more energy
and their oversized liver and spleen shrank
dramatically. Six patients we treated prior to
puberty also showed an increased growth
rate."

MPS 1 is a recessive disorder with an esti-
mated incidence of one in 100,000. About
one in every 200 to 300 people in the United
States iTiay carry the defective gene for MPS
1 so that when two carriers have children,
about one in four of their offspring are born
with the disorder. The most severe form,
Hurler's syndrome, causes patients to die by
age 4 or 5 on average.

"Until now, the only treatment alternative
was bone marrow transplantation, and
besides complications associated with trans-
plantation, doctors can't find matching
donors for all children who need one,"

Muenzer said.

Doctors gave the purified laboratory-gen-
erated enzyme to patients intravenously each
week for a year and evaluated them exten-
sively at six, 12, 26 and 52 weeks before ana-
lyzing and reporting their findings.

The researchers now are conducting a sec-
ond study known as a Phase III, double-
blind, placebo-controlled trial at six centers
across North America and Europe.

The chief sponsor of the clinical trial was
Biomarin Pharmaceutical, and it also was
supported by the Ryan Foundation for MPS
Children, the Harbor-UCLA General Clini-
cal Research Center and UNC's General
Clinical Research Center.

Researchers discover gene
responsible for cilia, lungs'
natural cleaning system

University of North Carolina at Chapel
Hill scientists have discovered the human
version of a gene and gene product that is an
essential component of the tiny hair-like
whips called cilia that cleanse the lungs.
They did it by applying what is known about
comparable structures in single-celled organ-
isms that enable the tiny creatures to swim
around in pond water.

Such novel work will help other re-
searchers trying to understand and combat
chronic lung diseases, scientists said.

The team used knowledge developed by
cell biologists who have studied the cilia of
sea urchins and single-celled animals for the
past 40 years. To pinpoint the human gene,
they combined that knowledge with informa-
tion generated by international efforts to
sequence the human genome — all genes in
the body.

"It turns out that these structures are highly
conserved, or repeated, in nature such that
the cilia on a one-celled animal in a pond are
very, very similar to the respiratory cilia in
human airways," said William Reed, PhD,
research assistant professor of pediatrics.
"We relied on that high degree of similarity
in structure and protein sequence to pull out a
human relative of the animal gene."

The gene produces a large protein essen-

tial for generating forces that power the
whip-like movement of cilia. Reed said. Be-
sides identifying it, they also showed that the
gene is "turned on" in cells as they begin
growing cilia.

About 80 percent of epithelial cells in
healthy human airways are ciliated, he said.
They sweep mucous and trapped particles
and disease-causing organisms into the throat
where they are usually swallowed and elimi-
nated.

Ciliated cells are injured and lost when flu
viruses infect the lungs, for example. This re-
duces the ability of the lung to cleanse it.self
Normal recovery involves regeneration of the
ciliated cells by a repair process that is poorly
understood.

The bottom line of the research is that —
now that they have located a human gene
"linked" to the appearance of ciliated cells —
they have created a new way of following
when ciliated cells appear in the lung, the sci-
entist said.

"In chronic lung diseases such as asthma,
the repair process can be slowed or halted,"
Reed said. "Expression of this gene can be
used as a tool to understand the repair process
and how it is interrupted in asthmatics."

The gene may also be useful to scientists
studying a less common disorder called pri-
mary ciliary dyskinesia (PCD), he said. PCD
patients" cilia do not move normally. Such
people suffer chronic ear and lung infections
and can require lung transplants.

A report on the finding appears in a recent
issue of the American Joiimal ofRespiraloiy
Cell and Molecular Biology. Besides Reed,
authors include Johnny L. Carson, PhD.
Billie M. Moats-Staats, PhD, Ping-chuan Hu,
PhD, Margaret W. Leigh. MD, and Albert M.
Collier, MD of the departments of pediatrics
and cell and developmental biology, the
UNC Center for Environmental Medicine
and Lung Biology and the Frank Porter
Graham Child Development Center

"This is an good example of the way infor-
mation generated by the Human Genome
Project and fundamental cell biology can be
combined and translated into a human re-
search setting, " Reed said.

Special vaccines could prevent
insulin-dependent diabetes

Results of a new Uni\ersity of North Car-
olina at Chapel Hill medical study suggest
that vaccines can be made using plasinid
DNA that would inhibit de\clopmcnt of in-
sulin-dependent diabetes, a grow ing health
threat in the United States.

Plasmid DNA is circular genetic material
obtained from bacteria. A chronic intlanima-
tory disease, insulin-dependent diabetes, also
called type I or juvenile onset diabetes, re-
sults from cells of the body's own immune
system going awry and eventually killing
other cells needed to produce insulin.

In their experiments. UNC researchers
succeeded in preventing diabetes from start-
ing in special laboratory mice that de\ elop di-
abetes as they age. More importantly, the
scientists say. they also halted progression of
the illness in animals already affected.

■" TTiis work is \ery encouraging because it
has the potential to be useful in clinical set-
tings."" said Roland Tisch. PhD. assistant pro-
fessor of microbiology and immunology. "In
the past, our group and others could manipu-
late the damaging auto-immune response in
\ arious animal models for type I diabetes but
not in ways that would be readily feasible
clinically,"'

A report on the research appears in the
F-eb. 1 \ssuc of Ihe Jdunuil (iflnuniinoloi;}.

"Recently, a Canadian group in Edmonton
showed for the first time that islet beta cells
— the cells in the pancreas that produce in-
sulin — could be transplanted successfully in
people w ith diabetes." Tisch said. "For more
than a year, their patients ha\ e been free of in-
sulin injections. A key issue, however, is that
those indi\ iduals have had to take a cocktail
of drugs that suppresses their immune sys-
tems, and they might have to continue taking
it for the rest of their lives."

Such drugs are needed to prevent patients'
immune systems from destroying the trans-
planted beta cells, the scientist said. But the
compounds also could make recipients more
susceptible to infectious diseases and cancers
and produce other unknown hut serious con-
sequences when given over many years.

Tisch's group used genetic vaccines they
created to re-establish the natural balance be-
tween two kinds of immune cells — ThI
cells and Th2 cells. When misbehaving, the
former attacks the critical insulin-producing
islet beta cells, w hile the latter nonnally keep
the former from doing that. When Th2 cells
fail to do their job. Thl cells eventually lead
to type I diabetes.

Working on the team with Tisch are Jenny
Ting. PhD. professor of microbiology and
immunology, and Jeffrey A. Frelinger. PhD.
chair, of inicrobiology and iinmunology.

Study sheds new light on
Lyme disease; Hndings shape
vaccine development

New research on the tick-borne bacteria
responsible for Lyme disease likely will
make scientists think differently about how to
develop a more effective vaccine, according
to studies conducted at the University of
North Carolina at Chapel Hill School of
Medicine.

Just-published research findings put for-
ward that as a tick feeds on its host, molecular
changes occur on the outer surface of the
Lyme bacteria Borrelia bingdorferi that are
more complex than prev iously thought. Dur-
ing the tick's blood meal, its saliva transmits
the bacteria to the host.

"Previous research showed there were cer-
tain surface proteins that were expressed in
the tick gut and others that were expressed in
the host, and that a switch occurred en route
from the tick to the host. This paper shows us
that things are a lot more complicated." said
.'\rav inda M. de Silva. PhD. assistant profes-
sor of microbiology and immunology.

The findings were reported in the Jan. \(t
issue of the Proiccdiiifis nf the Nalioiuil
Acudcmyoj Sciences .

Researchers said the findings are impor-
tant because any effective vaccine must
prime the immune system to mount an anti-
body attack against foreign antigens — the
invader's outer surface proteins.

In their study, the researchers focused on
two ot the more than 1 ^i) membrane proteins
known lo be associated with B. burgdorferi:

OspA and OspC.

"We wanted to see how these two proteins
changed as the bacteria moved from the tick
gut to the host." de Silva said. "And to our
suiprise. w hat we observ ed was not simply a
matter of one protein being expressed in the
gut and another being expressed in the host,
as had been prev iously thought. During trans-
mission, what the tick actually spits into the
host is a bacteria population that is highly
variable, compared to the fairly homoge-
neous population found in the tick before the
blood meal."

In other words, four possible combinations
exist for the two surface proteins. Some bac-
teria could express only OspA, some only
OspC. some both and some neither

"In fact, during the tick feeding process we
found all four of these different combina-
tions."" de Silva said. Moreover, when the
study team looked at another Borrelia surface
gene called v IsE. it found a large number of
variations generated during tick feeding,
compared to only one or two w hen the tick
was not feeding.

"We are excited by the findings because
this once again supports the concept that
ailhropod vectors lue not just living or crawl-
ing syringes that go around inoculating bac-
teria."" he said. "There"s a developing biology
going on inside this vector The bacteria pop-
ulation essentially adapts during the trans-
mission process to maximi/e the chance of
infecting the host.""

The research was supported by grants
from the National Institutes ot Health ami the
Arthritis Foundation.

tuller Award winner

Alan Briggaman Is A Winner,
No Matter How You See It

By Pam Pearce

If you look at Robert Alan Brigga-
man. MD. through the eyes of a sci-
entist you see an

internationally-respected researcher
who is an acknowledged authority on cer-
tain diseases. But if you look through the
eyes of his colleagues, you see a physi-
cian known for strong leadership, with a
special brand of camaraderie and sensitiv-
ity to patients" feelings.

No matter how you look at it, it"s easy
to see that Briggaman. this year's recipi-
ent of the H. Fleming Fuller Award, has
made an important contribution to the
world of dermatology. In fact, if you look
through his eyes, you can see how he
chose a career in demiatology.

"When I studied medicine, I enjoyed
the visual aspects because my brain
works that way." Briggaman said, who re-
ceived his medical degree from New York
University. "I see concepts and ideas as
pictures, and dermatology seemed a nat-
ural for that. At the time I chose dermatol-
ogy, it was based largely on a
morphologic description of what you could
see in front of you."

Briggaman's accomplishments not only in
dermatology but at the School of Medicine
and the surrounding community garnered
him the H. Fleming Fuller Award, given an-
nually to a medical faculty member who ex-
emplifies compassionate patient care and
excellence in teaching. The Fuller Award is
given in memory of the Kinston physician
and longtime member of UNC Hospitals
board of directors for whom it is named.

Since joining the faculty of the depart-
ments of medicine and demiatology in 1967.
Briggaman has earned a reputation not only
in the area of research but as a caring clini-
cian, effective administrator and skilled
teacher. "He is the quintes.sential. quadruple
letter man says." said Luis Diaz. MD. derma-
tology chair, and Briggaman's successor. "He
has set high standards but required nothing
of anyone that he did not or could not do him-
self."

One gets a better picture of how high the
standards were when looking back at Brigga-

18

Robert Alan Briggaman. MD

man's accomplishments. He advanced from
his first day of residency in 1964 to full pro-
fessor in 1974 — a swift promotion. Papers
he authored in the 1 960s are widely cited as
classics in the literature and some are still
cited today, according to Clayton E. Wheeler.
Jr.. MD. dermatology chair emeritus. "This
was great science in dermatology in the
1960s and 70s. It opened many doors." said
Wheeler.

This was just the beginning of Brigga-
man's globally-respected research endeav-
ors. An acknowledged world authority on the
vesiculobullous diseases, he was an uninter-
rupted principal investigator of an National
Institutes of Health grant from 1972 until
2000. Among his numerous awards, the
MERIT Award (Method to Extend Research
in Time) from the NIH in 1990 is one of his
treasured. "1 was pleased to get the MERIT
Award from the NIH." Briggaman said. "Not
only does it give you 10 years of funding, it
gives you validation as a researcher." Brigga-
man is slated to receive the Rothinan Award
from the Society for Investigative Dermatol-

ogy, the highest award that is bestowed
for research activities, later this year.

Briggaman's high standards also can
be seen in the quality of his delivery of
care to his patients. "He has been consis-
tent in putting patients, their problems
and management first, realizing and
practicing that physicians at the School
of Medicine are here to serve patients
and not the reverse." Diaz said. As a re-
sult, many of his patients have requested
his services and have been loyal to him.
over the years. Although Briggaman re-
tired last year, he still sees patients once
a week.

One might think that with his numer-
ous awards, including the 1998 Distin-
guished Faculty Award, a man of his
stature might intimidate a young resi-
dent just entering the field. Quite the
contrary according to Darlyne Menscer.
MD, past president of UNC's Medical
Alumni Association. "He's the kind of
teacher who residents describe as sensi-
tive, caring and always available."

And. like the kind, compassionate,
soft-spoken humble teacher his students
describe. Briggaman credits his students. "I
have been blessed with outstanding students
and have been fortunate to teach students for
the last 25 years who exceed the standards for
the "top of the line.'"

His strong leadership served as a source of
guidance for residents and faculty as he
served as chairman of the department from
1987 until his retirement. At Briggaman's
chairmanship retirement dinner, Wheeler
credited his time, energy and productivity for
playing a large role in developing dermatol-
ogy at UNC as a department that eventually
became a "world-class operation." The
strides taken under Briggaman's leadership
and his commitment to research enabled him
to recruit top faculty.

He's called North Carolina home since
1964. "I've spent my whole academic career
here and I have loved it." Briggaman said. "I
loved serving under Dr. Clayton Wheeler, the
research I have done, the patients I have cared
for and the students I have taught."

The way Briggaman sees it. he's had the
"best job in the world." lj

UNC Tests New Liver
Dialysis Device

By Leslie H. Lang

The Uni\ersity of North Carolina
at Chapel Hill is one of four
medical centers nationally to
study the effectix eness of a li\ er
dialysis device for people whose damaged
or failing livers have affected the brain.

The one-year randomized control study
w ill look at the clinical and economic out-
comes of li\'er disease patients who receive
dialysis using the HemoTherapies Unit, as
compared w ith patients who receive stan-
dard medical care.

The de\ ice is the only liver-assist tech-
nology appro\ed by the U.S. Food and
Drug Administration for hospital-based
li\er dialysis for people w ith ad\ anced liver
disease, including those awaiting trans-
plant. The manufacturer. HemoTherapies
Inc. of San Diego, sees the de\ ice as a
""bridge treatment" to help stabilize people
awaiting li\ er transplant. The company also
said the unit may postpone and possibly re-
duce the rate of fatalities associated with se-
rious li\er diseases such as hepatitis,
cirrhosis, drug overdose and drug toxicity.

Hov\e\er. until now. the device's effec-
tiveness had not been compared to standard
care in a large number of cirrhotic patients
who develop acute hepatic encephalopathy.
This neurological disorder stems from tox-
ins — mainly ammonia — arising from the
gastrointestinal tract that bypass the dam-
aged liver and go directl) to the brain. There
they can disrupt neurotransmitter function,
causing mental deterioration, including
coma.

Standard medical care for acute hepatic
encephalopathy involves treating the patient
with lactulose, a non-absorbablc liquid that
eliminates ammonia along with stool.

""Six out of 10 times, it relieves the en-
cephalopathy. But if it doesn't work, we give
antibiotics to eliminate ammonia-causing
bacteria in the GI tract." said Roshan
Shrcstha. MD. associate professor of medi-
cine and medical director of the liver trans-
plantation program. Standard therapv takes
about live days to work.

Shrestha is a principal investigator m this

"post-
market"
study. He
and col-
leagues at
UNC. the
Mayo Clinic,
the University
of Colorado
Health Sciences
and the Medical
College
Virginia Hos-
pitals will en-
roll 200
patients. They
will be ran-
domized to re-
ceive either three
dialysis treatments
or standard medical therapy. Researchers ex-
pect that many patients will be drawn from
the liver transplant waiting list. All patients
will have been diagnosed vv ith at least stage
2 acute hepatic encephalopathy based on
a scale of 0 to 4 w herein 0 equals normal and
4 equals coma.

The study will compare the follow ing end-
points: survival, bridge to transplantation,
length of hospitalization and lime in inten-
sive care.

■"First we'll look for and correct factors
that can precipitate encephalopathy in
thesechronic cirrhotic patients." Shrestha
said. ""These may include gastrointestinal

Selective
Removal/Addition
of Molecules Across
the Liver DIcdvsis
Membrane

bleeding

or bleeding

internally, infection, dehydration, not taking

medication properly or a high protein diet.

Once we conect those, we'll treat with either

lactulose or liver dialysis."

The device is a closed system, a compact
cabinet on wheels that uses a patented semi-
permeable membrane to absorb nitrogen-
based toxins. Patients are attached to the unit
via a catheter inserted into the femoral vein in
the groin or into a neck vein. Blood Hows
into the dialyzer for cleansing and is then re-
turned to the patient v ia that vein. Fach treat-
ment lasts four to six hours.

"So far, the anecdotal ev idence for this in-
dication looks prettv impressive. But we
have to see for ourselves w hether the dev ice
really works." Shrestha said. ""The trial will
continue for at least one year or until we en-
roll enough patients."

Shrestha's co-investigators at UNC are
Michael W. Fried. MD. Jeffrey H. Fair. MD,
and Steven L. Zacks, MD.

Each year, more than 25 million people in
the United States are aftliclcd w ilh liver and
gallbladder disease and more than 2fi.(X)0die
ot chronic liver diseases and cinhosis. There
are 1 6.(M)() patients on the nation's liver trans-
plant wailing lists, but only .5.000 livers are
donated each vear. J

News
Briefs

Seed Grants go toward
innovative research,
prevention projects

UNC's Lineberger Comprehensive Can-
cer Center has awarded nine Seed Grants
worth $205,000 for new studies in cancer re-
search.

The grants support new and growing UNC
research projects in innovative areas. The
grant program helps launch smaller projects
that could lead to more in-depth studies in the
future.

The grants were made possible by the
Schechter Foundation, the Brody Brothers"
Foundation and the Felix Harvey Founda-
tion, all of Kinston: the Foundation for the
Carolinas of Charlotte: the A.E. Finley Foun-
dation Inc. of Raleigh; and the Cemala Foun-
dation Inc. and the Hillsdale Fund Inc.. both
of Greensboro.

Newly-funded projects include:

• Valerie Murrah. DDS. MS, professor of di-
agnastic sciences, will study the effects of the
use of smokeless tobacco and certain viruses
as causes of oral cancer. While smoking is
considered the primary cause for this type of
cancer, smokeless tobacco and the virus
known as human papillomavirus may also
contribute to the development of oral cancer.

• David W. Ollila, MD. assistant professor of
surgery, is studying the indicators for the
spread of melanoma to the lymph nodes.

Doctors measure the thickness of most
melanomas to predict whether they will
spread.The thicker the melanoma, the more
likely it is that it will spread to the lymph
nodes. Thickness is not an absolute measure,
however, so Ollila hopes to find better ways
to predict if the melanoma will spread be-
yond the skin to lymph nodes or internal or-
gans.

• Gary W. Reuther. PhD. postdoctoral fellow
in pharmacology, proposes to study the caus-
es of various types of leukemia by identify-
ing oncogenes in the human body.
Oncogenes are altered versions of normal
genes, which can lead to the development of
cancer. A new technique for identifying these
altered genes has been developed, but it has
yet to be extensively used with human cancer
samples. Reuther hopes to use this new tech-

nique to identify oncogenes that are ex-
pressed in various leukemias. which may fur-
ther the understanding of how leukemias
develop and progress.

• Patricia Rivera. MD. assistant professor of
medicine, will focus her research on the early
detection of lung cancer. In Rivera's study.
100 patients at high risk of lung cancer will
be evaluated using the Lung Imaging Fluo-
rescent Endoscope, which detects pre-malig-
nant bronchial lesions. Patients with
abnormal lesions will continue the study
with repeated LIFE bronchoscopies, allow-
ing doctors to study the progression of these
lesions, and they will also be interviewed to
determine the relation of the lesion. Rivera
hopes this study will lead to better lung can-
cer screening strategies and more rational as-
sessments of the risk of development.

• Carol G. Shores. MD. assistant professor of
surgery, is studying sentinel node biopsies in
head and neck cancer. This technique for de-
tecting the spread of cancer to regional
lymph nodes and may reduce the need for
more extensive neck surgeries. In addition,
lymph nodes from patients who have head
and neck cancer will be examined by a sensi-
tive new test, which may detect small areas of
cancer that would have been missed by stan-
dard examination.

• Jozef Spychala. PhD. research assistant
professor of pharmacology, will concentrate
on breast cancer studies, particularly on a
function of a natural compound in the body
known as adenosine. Spychala will explore
whether adenosine may be released at high
levels from more aggressive breast tumors,
possibly helping the cancer to escape im-
mune reaction and grow faster. If adenosine
is released at high levels, doctors may be able
to find a way to alter adenosine metabolism,
neutralize its tumor-promoting functions and
inhibit the growth of cancer cells.

• William K. Funkhouser. MD. PhD, assis-
tant professor of pathology and laboratory
medicine, will study cancers of the colon and
rectum. When these types of cancers are
hereditary, it has been shown that patients
will often have defective mechanisms for the
repair of DNA. Suiprisingly. these patients
often survive longer than those who have no

family history of colon cancer.Some patients
who have no family history of colon cancer
also have the repair defect, and they, too, tend
to live longer. Funkhouser plans to study
colon cancer patients who do not have a fam-
ily history of cancer to see how the presence
or absence of the repair defect relates to fac-
tors such as patient survival, patient race and
tumor growth.

• James R. Sorenson. PhD, professor of
health behavior and health education, plans
to study a new tool for aiding breast cancer
patients in deciding whether to pursue
genetic testing. Padents are often unclear on
how their personal values and beliefs should "
enter into a testing decision. This research
will develop a decision aid that will help
women and their genetic counselors consider
the role of the patient's personal values and
beliefs in making a decision. If effective, the
decision aid. which is a four-page question-
naire, should assist women in arriving at a
decision that they can live with.

Number of primary care
doctors statewide takes a dip

For the first time in four years, slightly
fewer primary care physicians are practicing
in North Carolina, a University of North
Carolina at Chapel Hill report indicates.
The total dropped by 16 doctors, from 6,380
in 1998 to 6,364 in 1999, a decline of 0.3
percent.

The decrease follows an 8.4 percent jump
in such physicians between 1997 and 1998
and a 4.8 percent increase from 1 996 to 1 997,
according to the Cecil G. Sheps Center for
Health Services Research's 1999 N.C.
Health Professions Data Book.

For 22 years. Sheps center staffers have
compiled the data book as an annual report
on health care practitioners in North Caroli-
na. Primary care specialties are considered to
be family practice, general practice, internal
medicine, obstetrics gynecology and pedi-
atrics. Of those, only family practice and pe-
diatrics saw slight increases.

"Slowing of the growth of primary-care
physicians in our state might just reflect a
bump in the data given that the N.C. Medical
Board has recently revised the way it issues
licenses," said Thomas C. Ricketts, PhD,

20

MPH. deputy director of the Sheps center
and associate professor of health pohcy and
administration at the School of Public
Health. "How ever, if it is real and reflects an
emerging trend, we should worry about
w hcther the state's primary care doctor sup-
pl\ is going to be able to keep up w ith its
rapid population growth."

In contrast to the primary care physician
supply, strong grow th occurred in the state's
nurse practitioner corps for the fifth year in a
row. Ricketts said. The number of physician
assistants also increased, reflecting a growth
rate of 15 percent, from 1998 to 1999 and 46
percent since 1994. Additionally, the state's
certified nurse midw ife supply increased by
more than 10 percent annualh for the past
four years, now standing at 1 53.

Since nurse practitioners, physician assis-
tants and certified nurse midwives offer pri-
mary care, a relationship might e.xist
between their rise and the small decline in
primary care doctors, the researcher said.

The data system is funded by the North
Carolina Area Health Education Centers and
UNC's Office of the Provost. To order the
1999 edition of the data book, send an e-mail
request to hp_data_coord@mail.schsr.
unc.edu. County and region level data are
a\ailable online at www.shepscenter.unc.
edu/hp. A free pocket guide. "1999
Health Professions Supply by County." also
isa\ailable.

Preventive Medicine
Residency Program is
Honored

The Pre\enti\e Medicine Residency
Program in the UNC School of Medicine's
department of social medicine has been
awarded the 2(KX) Physician Training Award
in Preventive Medicine from the American
Cancer Society.

The four-year, S.^fH),(KK) award will spon-
sor three residents to complete their training
in preventive medicine. The grant aims to
encourage and assist the development ol
promising indiv iduals who will pursue
careers in preventive medicine. One goal of
the program is to create a cadre of acadcmi-
calK oriented physicians trained in prevcn-
tive medicine who have the potential
to become leaders in research, education
and intervention.

Through the program, the cancer society
seeks to support phv sicians in accredited res-
idency programs that will lead to eligibility

for certification in preventive inedicine.

During the two-year residency, the resi-
dents will pursue a master's degree in public
health and participate in field training that
w ill develop clinical and research skills in
cancer prevention and control and complete
a related research project.

UNC Health Care gets
$300,000 to help prevent
traffic-related injuries in
Orange County

The Trauma Outreach and Injury Preven-
tion Program has received a $300,000. three-
year grant from the N.C. Governor's
Highway Safety Program to target traffic-
safety issues in the Orange County.

Michele Ziglar. RN. MSN. director of
UNC's Trauma Outreach and Injui^ Preven-
tion Program, w ants to attack the "disease"
of trauma by preventing pedestrian and bicy-
cle injuries and car crashes.

According to research Ziglar compiled
from UNC Hospitals' trauma registry and
the Highway Safety Research Center at the
University of North Carolina at Chapel Hill.
car crashes in Orange County account for the
highest percentage of patients — about 33
percent — admitted to UNC Hospitals be-
cause of injury. Pedestrian and bicyclist in-
juries and the occupant death rate from
lightweight pickup truck crashes also are
higher in Orange County than in the rest of
North Carolina.

"There are several factors that contribute
to injuries and deaths." Ziglar said. "Only
about 53 percent of the children ages 12 or
younger involved in car crashes are ade-
quately restrained by child passenger safety
dcv ices. Other factors include speeding, al-
cohol use and aggressive driving."

The S3()().()()()'grant will be used to estab-
lish and support a Sale Communities Coali-
tion for Orange County. The goal of the Safe
Communities Coalition is to decrease traffic-
related injuries and their associated costs by
using the expertise and energies of the in-
volved community.

"Injuries are not accidents that just hap-
pen." Ziglar said. "They are. rather, pre-
dictable and preventable events that can be
controlled w ith proven strategies. The Safe
Communities concept works because it puts
injury prevention into the hands of the people
in the community - the people affected by
the problem. When a community responds to

an identified problem by joining its re-
sources, a tremendous amount of w ork and
change can occur."

AIDS physicians open clinic
in Lumberton

Infectious disease experts at the Universi-
ty of North Carolina at Chapel Hill School of
Medicine have started a new AIDS clinic at
the Robeson County Health Department in
Lumberton.

The clinic, open Mondays, will allow
HIV-positive and AIDS patients to be treated
near their homes instead of driving five or
more hours to Chapel Hill and back.

"If you're a single mother, for example,
who is infected with HlV. the virus that caus-
es AIDS, you shouldn't have to drive so far
for a 15-minute doctor's appointment, espe-
cially if you don't own a car," said Charles
van der Horst. MD. professor of medicine
and director of UNC's HIV/AIDS clinic.
"Recently we discovered that 120 people,
which represents 10 percent of the patients
coming to our clinic in Chapel Hill, were
from Robeson County, and so it's a big prob-
lem dow n there."

Robeson, one of North Carolina's poorest
counties, is not among its most populous, he
said. Still, it suffers one of the nation's high-
est sexually transmitted disease rates.

"Fifty percent of the syphilis cases in the
United States are diagnosed in fewer than 30
counties," van der Horst said. A $10().00()
grant from the N.C. Department of Health
and Human Services, made possible by fed-
eral legislation know n as the Rv an White
Bill, w ill support clinic operations for a year,
he said.

Each week, Dickens Theodore, MD, or
Becky Stephenson, MD. of the department
of medicine will accompany family nurse
practitioner Laurie Frarcy to Lumberton to
sec patients.

"This clinic, while a small and modest be-
ginning, is really a landmark opportunity not
only to provide compassionate humane care
for those who arc often marginalized on the
fringes of society but also to help stop the
spread of HIV." van der Horst said. "We hope
that it will serve as a catalyst for local com-
munities and medical centers lo step forward
and help out as well."

21

Diabetes Treatments
Undergo Quiet Revolution

Between the 1 950s and 1 994, treat-
ments for diabetes patients
changed httle, a leading physician
says, but in the past five years, a
quiet and highly beneficial revolution has
taken place. Now patients can control their
blood sugar levels far more precisely than in
the past and dodge complications of the ill-
ness until late life.

"Pretty much every year since 1995
there's been a major to moderate advance in
our drug treatment possibilities in diabetes,"
said John B. Buse, MD, associate professor
of medicine at the University of North Car-
olina at Chapel Hill School of Medicine.

"There also have been great improve-
ments in the old treatments as well — better
drug delivery systems for the old sulfony-
lureas, better insulin delivery systems, better
glucose monitoring and a greater under-
standing of the most appropriate doses to
give," Buse said. "So diabetes treatment in
2001 is about as different as it could be from
1994, and that creates certain opportunities
and challenges."

The greatest opportunity is that now just
about everyone's diabetes can be controlled,
but the therapies are expensive. Another
challenge is that because most U.S. doctors
finished their training before the advances
occurred, many still are not yet up to date
on them.

"Still another major challenge is that more
than half the children who develop diabetes
now have type 2, which classically devel-
oped in adults," he said. "Now, our children
are often as overweight and sedentary as 50-
and 60-year-old people of a generation ago.
They are actually developing the middle-
aged fomi of the disease."

Buse spoke in January at an American
Medical Association briefing in New York at
the New York Acadeiny of Sciences. His
talk, "New and Future Treatments of Hyper-
glycemia in Type 2 Diabetes." aimed to bring
the new developments in diabetes care to the
attention of other doctors and the general
public.

"Recent clinical trials have shown that

John B. Buse. MD

mamtainmg
nornial blood
sugar can pay
off in fewer
complica-
tions," said
Buse, who
also directs
UNC's Dia-
betes Care
Center.
"Among
these compli-
cations are
heart disease,
peripheral
vascular dis-
ease, stroke, nerve damage, eye problems
and kidney disease in both type 2 and type I
diabetes."

Drug improvements include:
•new sulfonylureas that stimulate the
pancreas to produce more insulin.

• metfoimin, which improves the liver's
natural response to insulin, which is to
prevent excessive sugar release into the
blood.

• alpha-glucosidase inhibitors, which
function by slowing starch breakdown and
thus delivery of sugars from the intestines
to the bloodstream.

• megitinides, fast-acting, sulfonylurea-like
compounds that also stimulate natural
insulin production.

• thiazolidinediones, which are insulin
sensitizers that allow insulin to be used
more efficiently and promise to reduce
heart risks associated with diabetes.

Insulin, generated by the pancreas in
healthy people, supplements or replaces in-
sulin in the blood to enable the body to me-
tabolize sugars. Buse said. Its puipose is to
signal the liver to stop making glucose.
When insulin levels are low, the liver starts
pumping glucose out and muscles and fat
stop storing it so that the brain will get
enough. When glucose levels fall, such as
after exercise or not eating for prolonged pe-
riods, less insulin is needed.

"The body is really blind to what the level
of glucose is, and so it needs the insulin sig-
nal to stop making glucose and to start stor-
ing it," he said. "The old techniques for
artificial insulin delivery didn't allow us to
match up things very well."

In type 1 diabetes, cells that make insulin
are destroyed by a selective iinmune process.
Treatment involves the best possible replace-
ment of insulin production. New faster-act-
ing insulin analogs created by recombinant
DNA techniques behave more like the
natural insulin that flows directly into the
pancreas' portal vein and then throughout
the body.

In type 2 diabetes two problems occur.
One is that the body doesn't produce quite
enough insulin, and the other is that the in-
sulin that is generated doesn't work as well
as it should in tissues that respond to it. Met-
formin improves the liver sensitivity to coun-
teract that second problem, while other drugs
boost production.

"The future of diabetes treatment is
promising," Buse said. "This year we should
get a new long-lasting insulin, a new short-
acting insulin and several other drugs. The
recent gains are just the beginning." U

Student Research Day

It was a day for dressing up. A day for
wearing suits instead of scrubs for some
students, or sweatpants and jeans for
others. A day to look cool under the
pressure of presenting months of research
and hard work in front of a panel of promi-
nent ph> sicians and one Nobel Laureate.

On January 31.52 School of Medicine
students displayed their faculty-mentored re-
search through slide and poster presentations
at the John B. Graham Student Research So-
ciety's 33rd annual Student Research Day.

"It's a source of pride for them and the
school," said Chen, 1 F. McCartney. MD, ex-
ecutive associate dean for medical educa-
tion. "These students are making significant
contributions to medical research."

Students, divided among a group of slide
presenters and four groups of poster presen-
ters, exhibited their research in front of a
panel of physicians and faculty members,
who judged them and then awarded students
from each of the groups. Research topics in-
cluded hybrid total hip arthroplasty, inborn
errors of metabolism and mutant Epstein-
Barr\irus.

Eight students were presented w ith the
.Michiko Kuno .Award at a banquet follow ing
the presentations. The Scott Neil Schw irk
Fellow ship also was awarded to Adam Zana-
tion, class 2(J()2, who created a slide presen-
tation of a three-dimensional raft modeling
of human head and neck squamous cell car-
cinoma.

One of the biggest highlights of the day
was the opening lecture by Nobel Laureate
Joseph Munay, MD, who gave the Ralph R.
Landes Lecture on "The Joy of Caring."

Murra\. is emeritus professor of surgery.
Harxard Medical School, and chief ol plastic
surgery at Brigham and Women's Hospital
and at Children's Hospital .Medical Center in
Boston. One of Murray's greatest achie\ e-
ments was to perform the first successful
human kidney transplant in \95-X. Murray re-
cei\ed the Nobel Prize in Medicine in 1990
for his discoveries concerning organ and cell
transplantation in the treatment of human
disease, j

Sccoml-yeur student Michael W'u presented his poster display of a three-diineiisinnal
activation map correlalini; witli predicted tlher orientation in a pita's left ventricle in
front of a panel of judges.

Michiko Kuno Award winners:

Patrick C. Hines, class 2000, slide presentation: -Intracellular cyclic AMP promotes sickle

RBC aggregation and adhesion to laminin"
Read Pukkila-Worley, class 2003, poster presentation: 'The cryptococcus nci>tormans

adcn\ late cNclase (CC AC 1 ) gene regulates pathogenicity and mating"
Hoke \\. Pollock, class 2002, poster presentation: "Turning to changes in ineraural time

ditferences in the auditory cortex of the unanestheti/ed rabbit"
Rhonda Vestal, class 2002, poster presentation: "The effect of rapacuroiuum on the subse-
quent neuromuscular effect of cisatracurium or rocuronium in elderly surgical patients "
Brad Anglemeyer, class 2003, poster presentation: "Accuracy of weight estimation by

emergency medical personnel"
Peter C. Nichols, class 2(M)3. poster presenlalion: "Portal image registration using normalized

mutual infoniiation"
Dalton McLean, cla.ss 2(M)3. slide prcscnialion: "Analysis of second-site mutations restoring

the function of the gonococcal hemoglobin receptor"

Scientists Bypass Major
Hurdle to Aid Hemophilia

By Leslie H. Lang

For the first time, scientists at the Uni
versity of North Carolina at Chapel
Hill have used a gene-therapy tech-
nique in animals to continually pro-
duce very high amounts of a clotting protein
similar to that lacking in people with hemo-
philia.

A lack of this protein, known as factor IX,
occurs in hemophilia type B. If human gene
therapy studies could yield sustained factor
IX production in high amounts, then hemo-
philia patients would not need daily injec-
tions of the protein.

The new findings, reported in a recent
issue of Molecular Therapy, also indicate that
the gene-therapy method used in the study
may be applied to hemophilia A, the more
common form of the disease. The report
concludes that the approach "may be useful
for the treatment of a wide variety of inherit-
ed diseases."

In animal experiments at Carolina and
elsewhere in recent years, the method used a
genetically engineered virus called AAV to
infect cells and thereby deliver a cloned gene
into an animal's body. Previous studies used
only type 2 of six known AAV serotypes,
each of which differ in their protein wrapper
This time, however, the Carolina researchers
tried five of the six, comparing factor IX pro-
duction of AAV types 1,3,4 and 5 with that
of type 2.

The results were startling.

"Surprisingly and unexpectedly, we found
the mice were producing amounts of this fac-
tor 100 to a thousand times more than we've
observed before," said senior study author
Dr. Christopher E. Walsh, assistant professor
of medicine at the UNC-CH School of Medi-
cine and clinical director of the university's
Gene Therapy Center.

"The purpose of this experiment was
to see if we could generate very high
protein production long-term," he added.
"These mice are now six months out and
iiiei .1 IX levels have remained very high

24

with no problems."

The mice studied were genetically bred to
have deficient immune system cells. They
were selected because the clotting protein
coded by the transferred gene was canine fac-
tor IX. In normal mice, the immune system
would mount a destructive attack against the
protein.

In previous experiments, UNC gene thera-
py researchers studied dogs with hemophilia
B, which resembles the disease in humans.
They gave recombinant AAV carrying ca-
nine factor IX to the dogs via direct intramus-
cular injections — similar to immunization
shots, such as tetanus. In two dogs, a simple
clotting test determined the gene was work-
ing, making protein in the muscle that circu-
lated in the blood. The animals also were at
reduced risk of bleeding. However, the
amount of protein produced represented 2
percent to 4 percent of the nomial amount of
factor IX in the blood both for dogs and hu-
mans.

"Our new research bypasses a major hur-
dle in gene therapy for hemophilia, but it also
represents the beginning of a long series of
experiments," Wal.sh said. "We know that the
one particular virus we've used for years now
works in mice, rabbits, dogs and primates. So
since these are just slightly different variants,
the assumption is they should work the same
way.

"And if in fact you can generate signifi-
cantly more protein, into the more therapeu-
tic ranges, and without the immune system
seeing it as foreign, then you could conceiv-
ably correct the disease."

While the UNC research demonstrates
that the approach works in muscle tissue,
might it also work in other organs, the brain,
liver, or kidney, for instance?

"My suspicion is the answer is "yes."'
Walsh said. "By changing a few proteins on
the surface, we can now direct these viruses
to places where we didn't think they could go
before and produce a lot of protein. You may
be able to replace factor IX with fill-in-the-
blank. whatever the body needs."

The gene therapy team is studying animals
with active immune systems, using the AAV
variants to deliver the gene for canine factor
IX into dogs.

"It's the results of these studies that the
U.S. Food and Drug Administration will use
as a benchmark for determining whether or
not clinical trials are warranted," said co-au- .
thor Richard J. Samulski, PhD, professor of
pharmacology and director of the Gene Ther-
apy Center. "I think we'll generate more
functional protein than is needed clinically."

Besides Walsh and Samulski, study co-au-
thors include Gene Therapy Center postdoc-
toral research associates Hengjun Chao,
PhD, principal author; Yaunbo Liu, PhD,
Joseph Rabinowitz. PhD, and Chengwen Li,
PhD. The research is funded by grants from
the National Institutes of Health.

Hemophilia B. a hereditary bleeding dis-
ease, affects more than 4,000 U.S. residents.
The disease affects males and results in
bleeding principally in muscles and joints.
However, internal bleeding, especially in the
brain, can lead to death. Treatment for the
disease involves intravenous injections of
blood products or, more recently, purified
factor IX. Traditional transfusion treatment
improves symptoms but fails to cure. D

Development

Notes

April 20 is due date for Class Campaign Gifts

Bob Timberlake prints
benefit pediatrics programs

Pediatrics programs at the North Carolina
Children's Hospital are about to benefit from
the sale of Bob Timberlake reproductions
that depict the late CBS newsman Charles
Kuralt.

The reproduction, entitled "Kuralt at
White's Creek." features Kuralt fly fishing in
a mountain stream.

"We get rights to sell as many reproduc-
tions as we can between March 1 2 and June
16." said Jake Lohr. MD, associate chair of
pediatncs. The Medical Foundation of North
Carolina. Inc. and The Educational Founda-
tion are selling the reproduction. A substan-
tial portion of the proceeds will go to
pediatrics.

Lohr and Timberlake have a long history.
Both men grew up in Lexington, NC, and
ha\e been friends since childhood. "Bob is
an incredibly generous man with a track
record of a special bene\olence toward chil-
dren." Lohr said. "The medical programs of
the Children's Hospital will greatly benefit
from his generosity, and we are most appre-
ciative."

Kuralt, who attended UNC's School of
Journalism, died of complications from
lupus in 1997.

"Kuralt at White's Creek" is to be un-
veiled during a gala Timberlake art exhibit
April 28 at UNC's new Eddie Smith Field
House. Sales of the reproductions, which
will retail for S2.'S(). began March 1 2.

For more information on how to
purchase the reproduction, contact
ki\erwood Hall Publishing at
(888) 307-7868 or visit the company's Web
site at www.riverwiKxJ hall.com.

Ten Class Campaigns ivrc w ell undcn\a)
with 150-1- medical alumni \olunteers rais-
ing funds from their classmates in honor of
their Reunions. The Progress Report below
is through February 1.2001. Remember
that Reunion Campaign results will be an-
nounced at the Spring Medical Alumni
Banquet Friday, April 27. Members of all
reuniting classes are
encouraged to be in
Chapel Hill to cele-
brate the results with
their classmates.

All medical alum-
ni who have not yet
made a gift are
encouraged to do so
by April 20 to count
in the results to be
announced at

Spring Medical
Alumni Weekend.

Contact Stephanie S t a d I e r
(Stephanie_Stadler(«' med.unc.edu) or
Brent Thomas (Brent_Thomas@unc.edu)
or call (800) 962-2543 if you would
like to make a credit card gift. You
may also visit www.unc.edu and click
on "For Alumni and Friends" to make
a cift.

LOYALTY FUND

COMMITMENTS &

ASSOCIATES

TOTAL CASH

CLASS

% PARTICIPATION

($l,000-^)

& PLEDGES

1946

16/27

(59%)

3

$6,700

1951

I4«7

(38%)

1

$8,900

1956

19/50

(38%)

9

$17,700

1961

.W51

(59%)

3

$8,000

1966

2S/64

(44%)

7

$116,150

1971

21/70

(30%)

6

$12,500

1976

36/116

(31%)

14

$37,500

1981

37/159

(23%)

8

$16,500

1986

27/146

(19%)

8

$10,500

1991

24/145

(17%)

3

$7,500

Miller quintuplets paint tiles for N.C. Children's Hospital

The Millerquintuplets, the state's first set of quints, have painted ceramic tiles that will
be pemianently installed in a huge wall oi' tiles in the new N.C. Children's Hospital, set to
open later this yciU'.

The Miller babies — Emery Elise. Grace Caroline. I lelen Marie ("Ellie"), Marguerite
Jackson ("Maggie") and Martin Thomas — were bom July 9, 1998, at UNC Hospitals.
ThcN are the children of Kent and Nancy Miller of Wake Forest. Their oldest child is Anna
Elizabeth. 4.

The tile-painting endeavor. Hands and Heels for Hope, is co-sponsored by Paint the
Earth, a painl-it-yourself ceramic studio, and The Medical Foundation of North Carolina
Inc.. the fund-raising arm of the N.C. Children's Hospital. Through 1 lands and Heels for
Hope, artists can paint 6-inch square tiles that will be pennanently mounted in the new
N.C. Children's Hospital building. The cost is S25 for one (ile or S4() for Iwo (iles. Pro-
ceeds benefit the N.C. Children's Hospital. Paint Ihc I-^ailh donates all lilcs. supplies and
gla/e and fires the finished works. A galadedicalion of the new .N.C. Children's Hospital
and the N.C. Women's Hospital takes place Sept. X.

2001 Dean's Receptions

More than 500 alumni, parents and
friends of the School of Medicine attend-
ed the Dean's Receptions held throughout
North Carolina and hosted by Dean Jef-
frey L. Houpt, MD.

Reception attendees were updated on
recent happenings at the School of Medi-
cine and had an opportunity to talk with
one another and faculty members. The re-
ceptions also served as a kick-off for the
annual Loyalty Fund Campaigns held in
these counties.

Receptions were held this year in Bun-
combe, Durham/Orange. Guilford. Meck-
lenburg, New Hanover and Wake
counties. Plans are underway now for
2001-02 receptions in Forsyth and Guil-
ford counties and Atlanta.

Gaiy Park, left, the new president of Rex Healthcare, talks with Robert Bashford.
MD. Medical Alumni Distinguished Teaching Professor at a donor reception in
Raleigh in February.

From left: H. Clifton Patterson. MD '74, Co-Chair Wake
County Loyalty Fund Campaign: Gordon B. LeGrand. MD '65,
ftinner president. Medical Alumni Association: Judy LeGrand
and Laura Patterson

From left: Diane and Vartan A. Davidian, MD '67: Sarah Ellen
and Joseph P. Archie, Jr, MD '68

26

Alumni
Notes

40s

G. Walker Blair, Jr.. MD '45, lost his
belo\ed u ite of 48 \ears. Sara Jo in 1996.
He married Francis in 1998 and writes "she
is putting up with me remarkably w ell." The
couple resides in Burlington. NC.

George Robert "Bob" Clutts, MD "45.

and w ife Sue ha\ e three children and three
grandchildren. He enjoys tennis, fishing and
farming.

Weldon Huske Jordan. MD '45. and his

wife Mar) Lynn li\e in Fayette\ ille. NC. He
serves as a trustee of Cape Fear Valley
Health Foundation. All four of their sons
became doctors; three of them graduated
from UNC.

Dean Winn. MD "45. enjoys golf, photog-
raphy, traveling. RVing and visiting his
grandchildren. His Parkinson's Disease has
progressed slowly over the last 10 years.

50s

(Jertrude A. Bales. MD '50. resides in
Rochester. NY. She enjoys volunteering for
Habitat for Humanity, golfing, grandmoth-
ering and restoring and designing stained
glass.

Elwood B. Coley, MD '50. is now working
two mornings each week at Lumberton
(NC) Children's Clinic. He enjoys garden-
ing, traveling and spending time with his
children and grandchildren.

Andrew M. Diggs. MD '50. volunteers at a
clinic seeing patients one to two days a
week. He is also working on a book regard-
ing "Fducational Concepts." Along with
his w ife Klizabeth. the couple has three chil-
dren and four grandchildren. They reside in
Palm Citv, FL.

Buel K. Grow. Jr., MD '50, lives in Belle
Mead. NJ with his wife Anne. He enjoys
watching his seven grandchildren grow up.
keeping up w ith the w orld. sports, reading,
music, walking, and occasionally sailing.
He plans on taking up kayaking this spring.

Henry (Hank) L. Stephenson, Jr., MD

"55. retired two years ago. Since then, he
has been trying to keep up with his three
sons, their wives and si.x grandchildren.
Along with his wife Frances, he has visited
Israel. Eastern Europe. Scotland, and Ire-
land.

60s

C.P. Eldridge Jr.. MD "60. recently retired
from the Radiologist and Diagnostic Clinic
of Houston. He had worked at the clinic
since 1966.

Ralph L. Bentley. MD "60. is the chaimian
of the board at Piedmonl Healthcare, a 75-
member multi-specialty group. He also
serves as the director of Piedmont Bank and
is on the board of directors at Gardner Webb
University. Mitchell Community College
and Da\ is Community Hospital. He resides
in Statesville. NC. with his wife Caroline.

J. Thomas Fox. Jr.. MD "60. moved to
Valle Crucis, NC. from Charlotte with his
w ife Landor after his retirement. They
enjoy outdoor activ ities. traveling, reading
and spending time with grandchildren. He
writes that both he and his w ife remain in
good health and feel very fortunate to he
able to enjoy a comfortable and ha|ip\
lifestyle.

Duncan S. Owen. Jr.. MD "60. recently re-
tired and is now focusing his attention on
reading, fishing, hunting and traveling. He
and his w ife Irene have three children and
vselcomed their first grandchild. Duncan S
Owen IV in September 1999.

Evin H. Sides HI, .MD "65. retired from a

private practice two years ago. He is now
working part-time on medical services at
Dorothea Di.x Hospital in Raleigh. N.C. as
an attending for UNC psychiatry residents
who are serving four months on medical
services. During his time off. he enjoys fly-
ing, boating, golfing and traveling.

70s

Bruce C. Becker II. MD "79. recently
achieved status as a certified physician ex-
ecutive and fellow in the American College
of Physician Executives. He is the v ice pres-
ident of medical affairs, education and re-
search and he resides in Bartlett, IL.

80s

Lauren Cosgrove. MD '80. is the chief of
her family medical center in Rockville.
MD. The center recently won Kaiser Per-
manente's National Diversity Award for its
creation of a Spanish-centered wing that
provides better health care to Hispanic pa-
tients.

Kenneth Hoilingsworth, MD '80. recently
retired from the US Navy. He is now in pri-
vate practice as a staff anesthesiologist ai
Nanticoke Memorial Hospital in Seaford.
DE. Married to Stacev La Motta. the couple
w elcomed the arriv al of a daughter. Brook
Noelle Hoilingsworth. on Dec. 27. 2(KX).

Wells Edniundson, MI) '80. is the medical
director of Springmoor Retirement Com-
munity. In his spare time. Wells enjoys fol-
low ing his daughter Erin's soccer career and
son Brian's UST.A tennis. You can reach
him at pc_bulldog(<' yahoo.com.

Mary Korvtkowskl. MI) '82. has two

teenage children and holds the position of
associate professor at the University ol
Pittsburgh School of Medicine. She has
been at the school tor approximately
1 2 V cars.

27

Paula Kreitler, MD '82, is a pediatric en-
docrinologist at Schneider Children's Hospi-
tal in Long, Island, NY. Along with her
husband Harry and daughter Rebecca, she
recently welcomed the arrival of new daugh-
ter Elizabeth. Email her at kreitzer@lij.edu.

Joanne Dykas Cameron, MD '85. has

practiced emergency medicine for the past
10 years. Joanne met "the man of her
dreams," David Cameron, and got married in
1996. The couple lives in Mattapoisett, MA.
You can reach her atjdcamdoc@aol.com.

90s

Dan Meulenberg, MD, '90. lives in Sand-
point, ID with his wife Lori and their two
daughters, Sophia, 7 and Jennie. 5. He loves
to hike, camp, bike, ski and garden. Email
himatdmeulen@micron.net.

Jill Obremskey, MD '90, is excited to be
back in North Carolina. She lives in
Ciiry with her husband William Obremskey.
MD, and their children Alexander. 6,
Nicholas, 4 and Analise, 2. Email her at
bjobremsk@aol.com.

Jerry L. Price, MD '90, is building a brand
new home in the mountains of Mayville, TN
with wife Phyllis and daughter Ken. He also
likes to go kayaking, mountain biking and
hiking. You can reach him at j-p-
price @ mindspring.com.

Angela R. Scott, MD, '90, is currently liv-
ing in Salt Lake City, UT while her husband
Walter Scott, MD completes his fellowship
in CT surgery. She works part-time at the
University of Utah in general ophthalmolo-
gy. She hopes to return to the East Coast this
summer. You can reach her at
angela.scott@mindspring.com.

Ami J. Shah, MD '90, is the clinical director
of Outpatient Services, Division of Im-
munology/Bone Marrow Transplant at the
Children's Hospital of Los Angeles. You can
reach her at ashah@chla.usc.edu.

J. Todd Williams, MD '90, has his own der-
matology practice in Asheboro, NC, where
he is involved in church and youth coaching
activities. He and his wife Denise have four
children: Jamey. 7, Josiah, 5, Caleb, 2. and
Wesley, two months. Email him at
todd@atomic.net.

Michael Kilby, MD '90, lives in Alabama
with his wife, Mia Kilby, MD "90, and their
two sons. He is an assistant professor at the
University of Alabama and is an advisor for
medical students. His research emphasis is
HIV pathogenesis and immunology. This
year, he will teach an honors seminar on
"Medicine and Society in American Film,"
which is directly related to his continued
addiction to movies. You can reach him at
mkilby@uab.edu.

Evan H. Black, MD '94, is an assistant pro-
fessor of ophthalmology at Wayne State Uni-
versity. He is the director of Ophthalmic
Plastic Surgery and Orbital Disease Section
at Kresge Eye Institute and resides in Royal
Oak, MI.

Raymond Carroll, MD '96, is the chief res-
ident of orthopedic surgery at Georgetown
University. Raymond and his wife Jennifer
welcomed their daughters, Lucy and Lila on
Dec. 10, 2000. Next year, he will complete a
fellowship in shoulder and elbow surgery at
Columbia-Presbyterian Hospital in New
York City.

Ibrez Bandukwala, MD '97, is a faculty
member of the Emory University Hospital
department of medicine. In October 2000,

Bandukwala married Claire Parker, MD '97
who is currently a fourth year resident in
OB/GYN at Emory University Hospital.

Deaths

Edwin A Rasberry, MD '39
H. Lee Large, MD '40
Stanley W. Chernish, MD '45
George Gentry, Jr., MD '59
William J. Murray, MD '62

28

President's
Letter

A Joy and a Privilege

It was a Tuesda\ night in early Fehruan'
and the office had been rough that day.
On call for six physicians, my beeper
had been unusually quiet as 1 prepared
tor bed and dared to hope that I could slip
through the next nine hours untouched. But
it was also my monthly twenty-four hours of
ER service call, so I forced myself to be real-
istic about my prospects. At 2 a.m.. the all-
too-predictable occurred. Sleeping far below
the surface, my rest vsas uninterrupted until
the beeper had chirped through its full se-
quence of pulses and my wife. Diane, finally
roused me \Mth a \ igorous shake.

L'pon arrival in the ER. the scene was busy
and loud, and the blinding fluorescent lights
woke up the other half of me that was still
clinging to its resting mode. The patient, an
84-year-old gentleman from Baltimore, was
visiting his grandson in Clinton and had no
local doctor. He was quite ill with an oral
temperature of 103.5. a respiratory rate of .^6.
and delirium. The only useful history came
from his grandson w ho reported that the pa-
tient had been hospitalized at Johns Hopkins
one week prior where "they weren't able to
figure out the source of his fever." Worse still,
the ER doctor said the patient had become
much sicker during his five hours in the de-
partment. With my new patient critically ill
and his daughter en route from New York —
she was an RN who'd already expresseil her

preference for helicopter transter to Duke —
it was plainly evident that I would need to re-
ciTjit my full complement of neurons to man-
age the patient and his family smoothly.

"It's been a joy and a privilege." I muttered
around 5 a.m. as I wrapped up my admit
orders and stumbled out of the ER to claim
for myself what remained of the night. The
sarcasm wasn't lost on the several nurses
standing within earshot.

A day later, after some rest and full sun-
light. I had settled back into the view that I
know to be true: It really is a joy and it really
is a privilege to live the life of a physician.
Our patients count on us to step into difficult
situations and bring order from chaos, to
make the diagnosis, to render proper care,
and to comfort the family.

A joy and a privilege. So it has been during
this year as Medical Alumni Association
president. I have thoroughly enjoyed repre-
senting the MAA at a variety of student and
alumni events. With my feelings of K)yalty
running even more deeply after these experi-
ences. I look ahead to further involvement in
the future. Let us all find ways to return a por-
tion of our resources to UNC. making our
school stronger for those who are to follow
behind us.

^\ \/xst»
With warm'regards.
I'aulE. VisciMD'f<4

CME/Alumni Calendar

April 8-12. 2001 - Waikoloa, Hawaii

Breast Imaging: Digital Mammography Update "01

April 10, 2001 - Chapel Hill
Emergency Medicine Researcli Forum

April 27-28, 2001 - Chap^l^ill , i

UNC Medical Alumni Association Spring Weekend

May 5-6, 2001 - Blowing Rock,, NC

16th Annual Meeting of the Glomerular Disease Collaborative

May 20. 2001 - Chapel Hill

Graduation

May 9-13, 2001 - Chapel Hill

Application of Molecular and Diagnostic Medicine

May 24-25. 2001 - Chapel Hill

22nd Annual TEACCH Conference: Educating Students with

Autism

June 9. 2001 - Chapel Hill

Medicolegal Seminar 2001

June 14-17. 2001 - Boca Raton Resort & Club. FL

Carolina Refresher Lectures: Care of the Surgical Patient

June 25-28. 2001 - Kaiwah Island. SC

Breast Imaging: Digital Mammography UfKlate "01

For more information about CME courses, contact the Office
of Continuing Medical Education. (919) 962-2118, or toll-free
through the Consultation Center, (800) 862-6264. To contact
the Alumni Affairs office, call (919) 962-6786 or e-mail
medical alumni@med.unc.edu.

Estate Planning Notice

Many individuals would like to make a major gift
to the UNC medical center, but cannot commit
current assets for such a purpose. Through a will,
however, anyone can make a more significant gift;
than they might ever have thought possible by
designating a specific sum, a percentage, or the
residue of their estate for the benefit of the medical

To provide a bequest, simply include a paragraph
in your will naming The Medical Foundation of
North Carolina, Inc. as a beneficiary. For example:

"I give, devise and bequeath (the sum of$

or ( % of my estate) or (the residue of

my estate) to The Medical Foundation of North
Carolina, Inc., a 501(C)(3) created to maintain
funds for the UNC medical center with principal
offices located at 880 Airport Road, Chapel Hill,
North Carolina."

This language creates an unrestricted bequest for
use by the medical center when and where the need
is greatest, or you may specify that your gift be
used for a particular purpose.

For further information on bequests, contact
Jane McNeer at (919) 966-1201 , (800) 962-2543,
orjmcneer@email.imc.edu.

Nonprofit Organization

U.S. Postage

PAID

Chapel Hill, NC

Permit No. 24

PERITJTCALS OEPARTWENT
HEALTH SCIENCES LIBRARY
C3 7535
CAROLINA CAMPUS 15^5

Medical Alumni

School of Medicine, University of North Carolina at Chapel Hill

UNC's new approach

to carlSig for
mothers and babies

^
^

Dean's
Page

The University of North Carolina at
Chapel Hill is consistently ranked
as one of the top five public univer-
sities in the United States. Perhaps
the major factor in establishing such rankings
is the amount of research support that the fac-
ulty is able to obtain from the National Insti-
tutes of Health (NIH). In that regard, the year
2000 has been a truly outstanding one for the
University. Indeed, in the year just complet-
ed, the University received over $207 million
in NIH grant support, making it the first year
UNC-Chapel Hill ever exceeded $200 mil-
lion in NIH awards.

You will be particularly pleased to learn
that the School of Medicine played a vital
role in this increase in NIH grant support to
the University. Specifically. $145 million —
or 70 percent of the $207 million received by
the entire University — came directly to the
School of Medicine. While sometimes the
exceptional accomplishments of our faculty
are taken for granted, the School of Medicine
has not always held such a lofty ranking in
terms of NIH awards. For example, in the
decade of the 1970s, the School of Medicine
received an average of $ 1 2 million a year
from the NIH and held a mean ranking of
27th out of the 125 medical schools. In the
1980s, the average yearly grant support rose
to $39 million, and we moved up to 20th
place among all medical schools. In the
1990s, the average annual amount of NIH
support was $93 million, and our ranking
among all schools of medicine had increased
to 15th.

While the research activity of the School
of Medicine has made remarkable progress
over the past three decades, our goal is to
move to a still higher level of academic ex-
cellence. We are convinced that the best way
to achieve this goal is by recruiting, develop-
ing and then retaining on our faculty a popu-
lation of outstanding young investigators,
people whom we believe will be working at
the cutting edge of science in the initial
decades of the 2 1 st century. Toward this end.
we have taken advantage of a number of NIH
programs and funding mechanisms that are
specifically designed to provide career devel-
opment opportunities for junior faculty
members. Each of these awards carries with
it a total of five years of protected research
time. They each link the junior faculty mem-

ber with a senior mentor who is expected to
assist the young person achieve research in-
dependence by the end of the award. At
UNC, we have been particularly successful
in working with our junior faculty to obtain a
variety of NIH-funded career-development
awards. These include:

— Clinical Associate Physician (CAP)
Awards and Mentored Patient-Oriented Sci-
entist (K30) Awards: These are designed for
young academic researchers whose goals in-
volve clinical and/or translational research
(i.e., research that involves direct interaction
with patients). At present. 16 of our junior
faculty members hold these awards, and six
additional applications are at the NIH pend-
ing review.

— Mentored Clinical Scientist (K08)
Awards: These are made to young faculty
members with a commitment to a laboratory-
oriented research career The School of Med-
icine currently has 14 K08 awardees, and
many others are either pending review or in
preparation.

In addition to these NIH-funded programs,
many other junior faculty members have re-
ceived career development awards from a va-
riety of prestigious foundations and other
funding sources. Examples include: Bur-
roughs Wellcoine Fund Career Awards (3),
Pew Scholars (3), Searle Scholar ( 1 ), Damon
Runyan Award ( 1 ), National Science Foun-
dation Presidential Scholars (2). Ellison
Medical Foundation New Scholar ( 1 ), Amer-
ican Heart Association Career Development
Awards (4), American Academy of Pharma-
ceutical Physicians Award ( 1 ) and Cystic Fi-
brosis Foundation Award ( 1 ).

In addition to these individual awards, the
School of Medicine has also received two
important institutional awards that will en-
able us to provide career development re-
search opportunities to our junior faculty:

• Tlie Clinical Research Curriculum (K30)
Program: This program was recently award-
ed to UNC as one of an initial cohort of 35 in-
stitutions. The purpose of the K30 Program
is to enable the School to develop a curricu-
lum specifically designed to train junior fac-
ulty members who wish to pursue careers in
clinical and patient-oriented research. A total
of 9 junior faculty members participated in
the K30 Program during this, its initial year.

• Building Interdisciplinary Careers in
Women 's Health (BIRCWH) Program: UNC
received a BIRCWH award in October as
one of an initial cohort of 1 1 institutions.
With funds from the BIRCWH award, we are
able to provide support for 75 percent of the
time and effort of as many as six young peo-
ple at any one time. The selection of these ju-
nior faculty members (referred to as
BIRCWH scholars) was based upon their
commitment to research careers in areas of
vital importance to women's health. Support
from BIRCWH grant assures a scholar of
mentoring, protected research time and assis-
tance in writing his or her individual career
development grant application.

Thus, I am convinced that UNC remains
well-positioned to further this tradition of ex-
cellence. Additionally, this new cohort of
outstanding young faculty members will
continue to provide the momentum that is
needed to carry us to a still higher level of
academic prominence.

m^

L

i^bhtft

Jeffrey L. Houpt. MD
Dean. School of Medicine

Medical Alumni
Association Officers

President

Thomas J. Koontz, MD "66
Winston-Salem

President-Elect

Ray M. Hay worth, MD "62
Kno.wille. Tenn.

Vice President

John Foust, MD '55
Charlotte

Secretary

JohnM. Herion, MD'83
Wilmington

Treasurer

William M. Hemdon, Jr., MD "81
Charlotte

Editorial Staff

Karen McCali

Vice President. Public Affairs &

Marketing

Lynn Wooten
Managing Editor

Laura Ertel, Leslie H. Lang,
Bemadette Gillis
Contributing Writers

Dan Crawford (pgs. 9, 13. 14, 15, IS,

19,20)

Jay Mangum (pgs. cover, 2, 3, 23)

Lynn Wooten (pgs. 5, 10, 11)

Chris Seward (pgs. 6, 7, 17)

Photographers

The Medical Alumni Bulletin is published four times
annually by the UNC-Chapel Hill Medical Alumni
Association, Chapel Hill, NC 27.S 14, Postage is paid
by the non-profit asscxiation through U.S. Postal
Permit No. 24. Address correspondence to the editor.
Office of Medical Center Public Affairs, School of
Medicine. CB#7«X). University of North Carolina,
Chapel Hill. NC 27514.

Medical Alumni

BULLETIN

School of Medicine, University of North Carolina at Chapel Hill

Contents

Features

A look at the new UNC Center for Maternal and Infant Health 2

Mini-Medical School: Medical sciences for the masses 6

The new leaderofCell and Developmental Biology 10

Thomas Koontz takes the helm of the Medical Alumni Association 14

Alumni Weekend honors many IH

Graduates get their big news on Match Day 20

Departments

Dean's Page Inside Front Cover

Faculty Notes 8

News Briefs 12

Development Notes 16

Research Briefs 22

Alumni Notes 24

President's letter Inside Back Cover

CME/Alumni Calendar Back Cover

On thr Cover: Murk HUiwcis. Ml), is an ii\sri In the UNC Center far Miitenuit ami Intant Health.

f

]"!llim,Uar^'^' '"''"' "'' ""'"' "'" '''^'""' " ^'"^'"'"' '" '''"""' P''"f''''"""'' ""'' "'^ P"''l'^ "bout the special issue related to

Striving for a 'profound impact' :
New center targets improved
health for mothers and babies

B> Laura Ertel

North Carolina has one of the na-
tion's highest rates for infant
mortality, low birth weight,
and premature birth. One out
of 30 of the state's infants is bom w ith a con-
dition serious enough to require specialized
medical care.

In light of these sobering facts, several
years ago leaders at the UNC departments of
pediatrics and obstetrics and gynecology, the
School of Medicine, the N.C. Women's Hos-
pital and the N.C. Children's Hospital got to-
gether to determine how best to address this
health crisis. In 1999. they decided to create
the UNC Center for Maternal and Infant
Health, an interdisciplinary center dedicated
to impro\ing the health of North Caroliii.i
mothers and babies.

The center pro\ ides integrated, coordinat-
ed care for high-risk pregnant women with
conditions like diabetes, hypertension and
sickle cell anemia and infants with complex
medical problems such as spina bifida, cleft
palate, and heart defects. Last November,
after a yearlong strategic planning and devel-
opment process, the center began its first
clinical service, providing diagnosis, consul-
tation and expert care to avoid or lessen the
severity of birth complications. It is the first
center of its kind and is creating a model for
other institutions to follow.

"By focusing on both mother and cliikl.
the UNC Center for Maternal and Infant
Health provides a unique structure lo deliver

Giniiy Diulek. RN. MEd. consults with a couple the center is helpini;.

comprehensive interdisciplinary care cen- cians and sophisticated technology now

tered on the family." said John Cotton. MD. prevalent at many medical centers, two major

an assistant professor in the Department of issues can he a lack ot comnumicalion and an

Pediatrics and pediatric director of the center en\ ironment perceived by patients as over-

"We hope the center will foster both basic whelming and uncaring, said Ken Moise,

and clinical research opportunities and be- MD. obstetrics and g\ iiecology director of

come a platform to educate professionals and the center and UpJohn Distinguished Profes-

ihe public about ihc special issiiex related lo sor anddiv ision chiet Dl iiiaieriial-l'elal medi-

perinatal care." cine in the Departinent of ( ihsteliics and

With the ma/e of subspeciali/ed physi- Continued <m pane 4

Continued from page 3

Gynecology. "The center strives to improve
communication between leaders in the fields
of obstetrics, pediatrics and surgery while
easing the tension for the patient from the
community who requires access to this high-
ly specialized care for her unborn child."

For both referring physicians and patients,
one of the most innovative and valuable fea-
tures of the new center is its focus on coordi-
nation of care, said Lucy Siegel, the center's
executive director. "Each patient enrolled in
our perinatal service is assigned to a perinatal
nurse care coordinator. This coordinator is
the interface between the referring physician
in the community and the medical team at
UNC, providing one efficient and timely
point of contact to keep the referring physi-
cian fully informed about the patient and the
treatment plan and facilitating communica-
tion with the UNC subspecialists. The care
coordinator also provides a seamless experi-
ence for each pafient, consolidating appoint-
ments to minimize trips to the hospital,
making sure each woman understands her
plan of care and providing counseling, health
education and emotional support during the
prenatal period."

Continuity of care is a focus for the new
center In the traditional health care model, a
pregnant woman enters a health care system
under the care of her obstetrician. When the
baby is bom, the infant's care is transferred to
the pediatrician. In the case of high-risk preg-
nancies and infants, this lack of continuity
can lead to fragmentation of care and mis-
communication of important information.

Because UNC specializes in high-risk pre-
natal care and the care of high-risk infants,
the need for an integrated system is acute.
This summer, therefore, a pediatric nurse
care coordinator will join the center to focus
on the ongoing care of infants with medical
complications. This nurse coordinator will
facilitate ongoing treatment and follow-up
appointments with the UNC medical team
4

Head of center impressed by its commitment

Lucille P. Siegel, MPH, was
recruited to UNC in August
1999 to help establish the UNC
Center for Maternal and Infant
Health. In addition to servmg as
executive director of the center,
she holds joint appointments as
a research assistant professor in
the departments of obstetrics
and gynecology and pediatrics.

Siegel, who has a master's of public
health degree from the School of Public
Health at the University of North Carolina
at Chapel Hill, worked for a decade at the
Delaware State Health Department in sev-
eral managerial positions. Just prior to
coming to UNC, she helped create and di-
rected a preventive medicine institute at the
Christiana Care Health System, a private.

Siegel

not-for-profit health care sys-
tem in Wilmington, Del.

She is thrilled at the opportu-
nity to focus on her primary in-
terest in maternal and child
health.

"When I heard what UNC
was planning to do, I felt that
the vision the physicians had
for this center made so much sense and the
impact it could have was so profound. This
center can help so many people," Siegel
said. "Now that I am here, much of my mo-
tivation is driven by the commitment of the
physicians, the care that they provide for
their patients and their willingness to go be-
yond what is expected and make sure that
their patients receive the best possible care.
That is so impressive to me."

and provide advice and support for the family
as they transition back home. The coordina-
tor will work with infants who delivered at
UNC as well as those who are seen by UNC's
pediatric sub-specialists in outlying clinics.
Medical problems, such as congenital heart
disease, may not always be identified early
on. Through this program the pediatric care
coordinator will assist families with access-
ing needed services and be an interface be-
tween UNC physicians and the infant's
pediatrician.

To better serve the state's growing Hispan-
ic population and indigent population, the
center has requested funds from a private
foundation to hire a third care coordinator. If
funded, this individual will focus on pregnant
women with medically complicated condi-
tions such as diabetes, hypertension
and sickle cell anemia who are poor or Span-
ish- speaking.

Another innovative ser\ice offered by the

center is the maternal transport program, in
which a nurse meets every high-risk pregnant
woman transported to UNC Hospitals by he-
licopter or ambulance and facilitates infor-
mation-sharing between the Hospitals and
the referring physician throughout the pa-
tient's stay at UNC. The nurse visits these pa-
tients daily on rounds with UNC physicians
and provides emotional support and educa-
tional information to each woman regarding
her specific medical problem. If the woman
delivers at UNC. the transport nurse coordi-
nator provides the infant's discharge summa-
ry to the referring obstetrician to keep the
doctor abreast of the mother's and infant's
conditions.

Many of these services are made possible
by grants and private donations received by
the denter, including support from The Med-
ical Foundation of North Carolina Inc.

The UNC Center for Maternal and Infant
Health also focuses on research to improve

HLAllHtARE

II MllK/

Michael and Amy Page of Wilson County, left, listen with Nancy Chescheir, MD, as Ann Ritter, MD, details for news reporters the delicate surgery that
was performed months earlier on Mrs. Page's unborn daughter, Hannah. The fetus was the first at UNC to undergo in utero surgery to correct for
complications caused by spina bifida.

the health of mother and child. TTie cen-
ter recently received a significant honor
when it was invited by the National In-
stitutes of Health to become a member
of its Maternal-Fetal Medicine Units
Network, a group of 1 4 academic med-
ical centers that participate in random-
ized clinical trials addressing medical
conditions associated w ith pregnancy.

In November, the center sent a ser-
vice directory and letter of introduction
to approximately 6(X) N.C. obstetricians
and other health care providers who
refer high-risk prenatal patients to UNC. If
you did not receive one of these packages
and would like information on the UNC Cen-
ter for Maternal and Infant Health and its ser-

•• Byfocusiitg on bolh mother aiul child,
the UNC Center for Malenial ami Infant

Healtli provides a iinic/ne .structure to
deliver comprehensive interdisciplinary
care centered on the family. "

John Cotton. MD

vices, visit the center's website at
www.mombaby.org or call the lead perinatal
care coordinator. Ginny Dudck. KN. .MIaI at
l919l9ft6-X()S6.

The Center's leaders arc excited
about the early feedback they have re-
ceixed from both referring physicians
and patients on the impact of these new
ser\ ices.

"It is rewarding to sec the impact on
the individual women and babies w ith
whom we work." Siegel said. "By help-
ing one famil\ at a lime, wc hope we
can ultimately make a prolound impact
on the health of mothers and children
throughout North Carolina." Zj

Mini-Medical School brings
medical science to life

Angela Kashuha, PliannD, works closely with
Myron Cohen, MD. m his infectious disease
research.

By Leslie H. Lang

II all began in 1990, in mile-high Denver.
Colo., at the University of Colorado
Health Sciences Center. Launched ini-
tially as a community outreach effort, an
alternative to the typical single-topic health
care lecture offered by community hospitals
across the country, few on the scene thought
more than 40 people would attend.

But before announcements could be

mailed out, a reporter got wind of the pro-
gram and wrote a small article on it for the
Rocky Mountain News. By day's end, more
than 500 people had signed up. filling the
course.

Today, more than 80 medical institutions
across the country offer a Mini Medical
.School program. And in October 2001 .
McGill University will launch the first pro-
gram in Canada.

Since its inception in 1995. the UNC Mini
Medical School remains one of the most
popular community-based lecture series in
the Triangle and, it seems, beyond. This year,
one retired devotee from Troy, N.C., drove
8.^ miles each way to attend.

Whatever the travel distance, enthusiasm
runs high among former attendees. They
make up more than half the audience of any
given session. Many are retired, some in their
late 80s and early 90s. But plenty
are younger than 40, including teen-agers
who attend with their high school science
teachers.

Price or perks?

What drives more than 400 people each
year to sign up for a series of lectures on top-
ics ranging from new radiation therapies to
the digestive system, from genome science to
fetal surgery?

Could it be the modest price and some
great perks? A fee of $25 pays for a series of
five two-hour evening lectures: a detailed
notebook complete with lecture summaries
and glossaries; an official T-shirt, embla-
zoned with the program's logo: and a chance
to hobnob with some of Carolina's finest bio-
medical researchers and clinicians.

It seems that a variety of reasons draw
people to the program. Some may be con-
templating careers in medicine or biomedical
research, or had done so at some time. Some
are spouses or partners of physicians and re-
searchers who want a better understanding of
biomedicine. Others want to learn how im-
portant medical discoveries are made. Still

others are looking for information that will
make them better medical consumers or that
might help them grasp the brass ring of ex-
tended healthy longevity.

Miffed about missing last year's sessions
"because we had to go away," one retired
couple said the best thing about Mini Med-
ical School is the hours of conversation it
provides both for themselves and their
friends.

The program's beginnings at Carolina
sprang, in part, from a pragmatic vision. In
early planning sessions, William Easterling,
MD, professor of obstetrics and gynecology,
and John Stokes, vice president. Public Af-
fairs & Marketing, viewed the principal goal
as infonning the infiuential public about the
importance of biomedical research. This,
they reasoned, would lead to support from
funding agencies.

Promotional activities for the program
made a point of targeting community lead-
ers, sending mailings to members of govern-
ment advisory boards and to members of
civic groups.

"But we also saw Mini Medical School as
an important service to the intellectual com-
munity and increasing the public's aware-
ness of health issues. Early on the series
focused on basic science and then it moved
on to clinical science." Easterling said.

From the beginning. Mini Medical School
faculty members were selected for their
teaching skills as well as their clinical and re-
search expertise.

"The UNC Mini Medical School became
an opportunity to showcase the enthusiasm
of our top researchers for their work and to
make science understandable and exciting to
lay people." Stokes said.

Soon it became a distinct honor among
faculty to be asked to participate in the pro-
gram.

"An exclamation point to the program's
success occurs when I see members of our
own medical faculty seated in the audience,"
Easterling said.

In more ways than one. the UNC Mini

Medical School helps put a face on the insti-
tution. Surveys re\eal that the program en-
hances the image of the medical school
among man\ Mini-Med graduates.

And it also puts a more human face on
physicians and biomedical scientists. Manx
in the audience were moved w hen a lecture
on bone marrow transplant was followed b\
a discussion w ith a patient about her experi-
ences with the procedure.

At Mini-Med there is always room for
humor. For this year"s session on digestive
diseases, the first speaker opened with a
meticulously labeled illustration of the
human digestix e system. On top sat the head
ofthe next lecturer

More than one fomier Mini-Med speaker
has slated how enjoyable the experience had
been, even enlightening. The basic re-
searchers are unanimous in the lesson
they've learned: scientists ought to spend a
percentage of their time talking to the public,
getting their points across in English rather
than the language ofthe laborator>.

The 'Deanlet'

Every medical school must ha\e a dean.
UNC Mini-Med is no exception. Call him
Director. Overseer Of All Things Medical,
or. as he likes to put it. "Deanlet." for the past
three >ears Myron S. Cohen. MD. professor
of medicine, microbiology and immunology
and chief of the di\ ision of infectious dis-
eases, has run the show.

Dubbed the "EmCee"" by some students.
Cohen's official duties as director ofthe pro-
gram ha\ e gone beyond his onstage eftbrts as
session host and discussion moderator to in-

A/i!/ir cnthuiiastii Mini-Mat "sludcnts" arc rcpecit ptuticipants.

elude advising on content planning and fac-
ulty selection. And he also has lectured on
topics tied to infectious diseases.

Indeed, his benign and often lighthearicd
presence at each session has made him an au-
dience favorite. On the evaluation sheet stu-
dents tuni at eveninu's end one often finds a

request that Cohen be returned to the podium
the follow ing year

Still, it is Cohen w ho insists that the pro-
gram's success never would have been
achieved without the key ingredient behind
the success of any medical school, "maxi" or
mini: quality faculty.

"Through this program we hope that stu-
dents develop an appreciation for the science
behind medical practice, the passitm with
which investigators at UNC pursue their
clinical and basic research, and the reason
why UNC-Chapel Hill has become one of
the lop-rated medical schools in the L'niled
Stales," Cohen said.

Miin-Miil atlr,iil>a
/iirv;i- aiul ilivcrn- iiiulieihc
troiti uiulcij^niiltitilc
>liiilciUf 10 fciuiirf.

Faculty
Notes

David Janowsky, MD, professor of adult
psychiatry, and Art Prange Jr. MD. are the

subjects of individual autobiographical
chapters, honoring their landmark contribu-
tions to psychopharmacology, in the new
book The Triumph of Psychophan?iacologv
andtheStoiyofCINP.

George Breese, PhD, professor of psychia-
try and pharmacology, has been selected to
receive the 2001 American Society for Phai-
macology and Experimental Therapeutics
Award for Experimental Therapeutics. This
prestigious award is given in recognition of
basic studies which contribute to therapeu-
tics. Breese received it in honor of his work
in the development of pharmacological treat-
ments for self-injurious behaviors.

Robert Hamer, PhD. has joined the Depart-
ment of Psychiati7 as professor of psychiatry
and biostatistics and director of biostatistics.

Susan Girdler, PhD. assistant professor of
general hospital psychiatry and behavioral
medicine, has been selected as the 2001 re-
cipient of the American Psychosomatic So-
ciety's Early Career Award for Contributions
to Psychosomatic Medicine.

Frank S. French, MD. professor of pedi-
atrics and director of the Laboratory for Re-
productive Biology, has received the 2001
Distinguished Andrologist Award from the
American Society of Andrology.

Peter Curtis, MD, professor of family med-
icine and director of the Faculty Develop-
ment Program, is the principal investigator
for "Integrating CAM into Health Profes-
sions Education in North Carolina." The
five-year grant was awarded to the Program
on Integrative Medicine by the National
Center for Complementary and Alternative
Medicine. The CAM Education Project
seeks to accelerate the integration of comple-
mentary and alternative education into the
health professions schools throughout the
state.

Steven H. Zeisel, MD, PhD, chair of the de
partment of nutrition, received the Dannon
Institute Award for Excellence in
Medical/Dental Nutrition Education from
the American Society for Clinical Nutrition.
The award was presented in recognition of

an outstanding career in medical/dental nu-
trition education. Zeisel's efforts were wide-
ly recognized to have had international
impact and reflect acknowledged excellence
in nutrition teaching or nutrition education
research that extends beyond the local insti-
tution and that includes innovations in med-
ical/dental education. A cash award and
inscribed plaque are provided by The Dan-
non Institute.

Zeisel was also elected to be president of the
American Society for Nutritional Sciences.
The society is the premier research society
dedicated to improving the quality of life
through the science of nutrition.

Anna Maria Siega-Riz, PhD, assistant pro-
fessor in maternal and child health and nutri-
tion, recently won the Mary C. Egan Award
from the American Public Health Associa-
tion Food and Nutrition Section for innova-
tion in public health, nutrition in maternal
and child health, and leadership in communi-
ty nutrition.

Boyd R. Switzer, PhD, associate professor
of nutrition, is serving on the Technical Ad-
visory Committee for the Office of Health
and Human Services at General Baptist State
Convention of North Carolina. This is the
largest African- American church organiza-
tion in North Carolina.

Aravinda de Silva, PhD, assistant professor
of microbiology and immunology, was re-
cently acknowledged in the New York Times
for his new findings on Lyme disease, which
may contribute to finding a more effective
vaccine, de Silva's ongoing research is in-
volved with Lyme bacteria or Borrelia
burgdorferi.

Jack Griffith, PhD. professor of microbiol-
ogy and immunology, recently received an
Ellison Foundation
Senior Scholar
Award in the
amount of
$150,000. Griffith
also received a
certificate and
rosette from the
Association for the
Advancement of Sci-
ence.

Griffith

Amelia F. Drake, MD, associate professor
of otolaryngology/head and neck surgery, as-
sumed directorship
of the UNC Cranio-
facial Center. Drake
has served for a
dozen years as the ■'

otolaryngologist for
the Cleft Palate/
Craniofacial Teain.
The team member-
ship also includes Drake
representation from

psycholog y , pediatric dentistry, plas-
tic surgery, orthodontics, genetics, oral
surgery, speech pathology, and social work. '
The strength of the team is its coordinated
care for patients with cleft lip and palate and
craniofacial issues, its leadership in the na-
tional organization (the American Cleft
Palate Association), as well as its research in
a variety of areas.

Blair Keagy, MD. professor and division
chief of vascular surgery, was named the first
George Johnson. Jr., MD. Distinguished Pro-
fessor of Vascular Surgery. Johnson has
served as a teacher, mentor, and role model
for young surgeons for more than three
decades. A pioneer in vascular surgery, he
helped develop UNO's Vascular Surgery
Service and Peripheral Vascular Laboratory,
and chaired the committees that designed
and implemented the day-surgery facility in
1992.

Mark Weissler, MD, professor of otolaryn-
gology/head and
neck surgery, was
honored with the ap-
pointment to the rank
of Joseph P. Riddle
Distinguished Pro-
fessor of Otolaryn-
gology. Riddle was
an outstanding busi-
nessman from the
Fayetteville area

who contributed substantially to the UNC
Division of Otolaryngology/Head and Neck
Surgery. His funding led to advances in the
study of otolaryngologic allergy and the es-
tablishment of an otolaryngology and micro-
surgery laboratory that bears his name.
Riddle's continued interest and support of

medical programs at UNC resulted in a sub-
stantial gift to UNC Lineberger Comprehen-
si\'e Cancer Research Center.

The tlrst Joseph P. Riddle Distinguished Pro-
fessor of Otolaryngology was W. Paul Big-
gers. MD. who passed away last year.
Weissler is the second to receive this honor,
in recognition of his 15 years of senice to the
UNC and his local, regional and national
work in head and neck oncology.

William Droegemueller. MD, has become
one of few to recei\ e an honorary degree of
Doctor of Science at the University of Col-
orado. The Board of Regents of the Uni\ ersi-
ty of Colorado recently presented him with
the degree in recognition of his contributions
as a teacher, researcher and author.

Droegemueller. clinical professor in the De-
partment of Obstetrics and Gynecology at
UNC. has made many contributions to
women's health. He has conducted research
in the area of intrauterine cryosurgery, and
because of his early pioneering work in diag-
nosing and managing intrauterine diseases,
thousands of women no longer face hysterec-
tomies.

In addition to his teaching and writing. Dr.
Droegemueller has played a significant role
in shaping and setting standards for women's
health care. As director of e\ aluation for the
American Board of Obstetrics and Gynecol-
ogy, he has demonstrated leadership that has
resulted in upgrading the standards for certi-
fication and helped ensure a higher level of
competency of today's obstetrics and gyne-
cology specialists.

Dr. Droegemueller is a 1960 graduate of the
University of Colorado .Medical School. He
is a fonner professor and \ ice chainnan at the
Colorado Uni\ersity Department of Obstet-
rics and Gynecology. Droegemueller ser\ed
as chairman of the Department of Obstetrics
and Gynecology at UNC from 1982 to 19%.
He has also written over 100 articles and
chapters in se\eral publications.

Shawn McC'andless, MD. assistant profes-
sor of pediatrics in the di\ ision of biochemi-
cal genetics and metabolism, has led a study,
which found that a \ast majority ol children
admitted to hospitals have a genetically de-
termined underlvint: disorder. The siudv

Georgette Dent. MD. peifonns a Pearls Day skit as a "Survivor

found such disorders accounting for more
than two-thirds of all children admitted to a
large full-service pediatric hospital o\er a
one-year period. The findings were present-
ed to the 2001 pediatric Academic Societies
and American Academy of Pediatrics joint
meeting in Baltimore, Md.

George F. Sheldon, MD, Zack D. Owens
distinguished professor of surgery and chair-
man of the department of surgery, recently
delivered the 175th Hunterian Oration at the
Royal College of Surgeons in London.

This lectureship is one of medicine's oldest
and most distinguished. Sheldon was admit-
ted as an honorary fellow of the Hunterian
Society, founded in 1819 and one of the old-
est medical societies of its kind.

Sheldon, who has served as surgery chair-
man at UNC for 17 years, is the chainnan of
the Association of American Medical Col-
leges.

James D. Fold.s. PhD. prutessor of Patholo-
gy and Microbiology and Immunology, re-
cei\ed the 2001 Professional Recognition
Award from the American Board ol Medical
Microbiology and American Board of Labo-
ratory Immunology. The award honors Folds
for 25 years of promoting the clinical im-
munolog\ and microbiology professions

through outstanding scholarship, training,
and education efforts and professional ser-
\ice. Folds, director of the William McClen-
don Clinical Laboratories, is the first
immunologist to receixe the annual award.

Caria Sueta, MD, was recently published in
the N.C. Medical Journal. She ciinsulted
with the Medical Review of North Carolina
to write the article, "Hospital Interventions
Improve Care of North Carolina Medicare
Patients with Acute Myocardial Infarction."
The results of the study showed that simple
hospital-based interventions, such as using
aspirin during hospital stay and receiving
correct medication once discharged, im-
proved the quality of care of Medicare pa-
tients w ho suffered heart attacks.

Suresh Mukherji, MD. associate professor
or neuroradiologN. was appointed to the edi-
torial board of American Journal of Neurora-
diology, the editorial board o{ Journal of
Computer Assisted Tonioi^raphy. the editori-
al board of the Intemational Advisory Board
ol'/iv/((/( Oceanian Jtn(rnal of Radiology.
guest editor of .S<7»//;(/n /// Ultrasound. CT.
and MRI. Advanced MR Imaging Tech-
niqnes. Volume 21 .

Faculty Profile

New directions for
CeU Biology

By Leslie H. Lang

During his graduate training in the
School of Medicine's Microbiolo-
gy Department in the early 1980s.
Vytas A. Bankaitis, PhD. never
once entertained a notion that someday he
would return to Carolina to head a depart-
ment he would promptly rename. In those
days, he would often grapple with uncertainty
about a career in science and the uncertainty
about making ends meet financially for his
family, which now included a new baby boy.

Today, the new head of Cell and Develop-
mental Biology is fully aware that such issues
were not unique to that young student. Such
doubts were endemic among many of his
peers, especially those with families. It has al-
ways been that way. whatever the graduate
field of study.

But Bankaitis found he could draw
strength from adversity. For one thing his
own family back home in the Cleveland.
Ohio, area had done the same. For another,
growing up the oldest of nine siblings made
adversity part of the territory.

"My parents were immigrants from
Lithuania. There were highly educated peo-
ple in my family, especially my grandfathers,
who were forced to abandon their professions
when they were displaced by the Second
World War. Circumstances dictated that they
support their families by toiling in menial
jobs. Education was a very important thing in
my family, and expectations were high from
the beginning."

And it also helped immeasurably to have
good local schooling. "I was vei7 fortunate to
have attended an outstanding public school
system in Fairview Park, a western suburb of
Cleveland. They offered advanced courses,
especially in high school, and I was thinking
medical school at the time. In fact, some of
the advanced courses were almost at the level
of first year medical school courses,"
Bankaitis recalled.

"But I found I was more curious about science
per se than I was about memorizing the neu-
roanatomy of tlie sbeep brain, for example. So I de-
cided in high scha>l to study science in college."

10

Vytas A. Bankaitis, PhD

A swimming athletic scholarship helped
propel him to a small school in Pennsylvania.
Edinboro State College, now Edinboro State
University. While enrolled there, he met a
new junior faculty member who worked in
bacterial genetics.

"I did extracunicular work in his lab and
became fascinated by the fact that, with rela-
tively simple manipulations. I could make an
organism do something that it ordinarily
couldn't do. In this case. I could make an or-
ganism grow under conditions under which
it ordinarily couldn't grow."

In 1978. Bankaitis graduated with his
BS in biology. Two years later, and with a
master's degree, he and his wife arrived in
Chapel Hill."

Those days were in the pre-genomic past,
in another century literally and figuratively: a
time when genome sequencing, gene mi-
croarrays and proteomics had yet to arrive in
scientific discourse.

Even so. in moments of prescience, the in-
tellectually adventurous might put an ear to
the rail and hear faint rumblings of a mighty
express on the way. one destined to change
the nature of biomedical research. More than

a few scientists had already tos.sed their bags
on board and jumped on for the ride.

At Carolina were a number of these indi-
viduals, top scientists and mentors all.
Among them was the late Phillip Bassford, a
microbiologist and bacterial geneticist.

"I owe my entire scientific career to Phil
because I was not sure I was going to contin-
ue in science when I came to his lab,"
Bankaitis recalled. "It was his way of train-
ing people, the way he did science, that made
all the difference.

"When I do a linear regression of my sci-
entific career, it all started here. So one of the
real motives for coming back to Carolina was
because I have always considered this my
scientific home."

Bankaitis pointed to an important lesson
he learned in Chapel Hill.

"I learned that science, when it's per-
formed in a collegial but high energy atmos-
phere, when there are opportunities for good
interactions with high quality people, be-
comes a lot of fun." he said. "I'm referring to
people on my doctoral thesis committee like
Clyde A. Hutchison, now a member of the
National Academy of Science: Janne Can-
non: Ken Bott: Fred Sparling, then chair of
the Department of Microbiology and Im-
munology: my mentor Phil Bassford: and
my student and postdoctoral colleagues,
such as Pat Ryan. Mike Janusz. Rick
Schwalbe. George Stewart, John Glass and
others — these were the people who really
made a huge difference for me by making
science fun."

At UNC. Bankaitis studied protein secre-
tion in the bacterium E. coli. He decided to
continue his research in protein secretion as a
postdoctoral but to study it in eukaryotic
cells. "So I went to CALTECH in 1984 as a
Helen Hay Whitney Foundation postdoctoral
fellow and for two years worked on protein
secrefion in yeast."

His independent career began as assistant
professor of microbiology at the University
of Illinois at Champaign-Urbana where he
was honored as an Arnold Beckman Scholar
in 1986. There he worked on protein secre-
tion in both yeast and E. coli "but very quick-

1\ m\ interest turned to the \east project we
were engaged in and have since expanded
into mammahan systems." he said.

The researcher joined the University of
.Alabama at Birmingham .Medical Center
Cell Biology I'aculty in 1992. During his
eight-and-a-half \ ears there, he served on the
Cell Biology .Ad\isorv Panel for the National
Science Foundation and the Cell Biology.
Microbial Ph\ siologv. and Microbial Genet-
ics stud> section for the National Institutes of
Health. He now serves on several editorial
boards and on the Cell Development and
Function 2 studv section for the National In-
stitutes of Health.

Less than six months into the new millen-
niuin Carolina beckoned with a departmental
chairmanship. The prospects of a return for
the cell biologist tantalized on a number of
levels. This becomes abundantly clear as Dr.
Bankaitis reflects on his decision with an ex-
planation both sincere and straightforward.

"Taking a chaimianship is not something I
e\er thought I'd do. I think what happens as
one gains experience and grow s as a scientist
is that one de\ elops a sense of how things
should be done. Also, at some point, we start
looking back on our careers and asking our-
sehes where we ha\e made a difference. I
think the most enduring impacts are made
w hen we help build units. v\ hen we foster in-
teractions betv\een scientists, when we
spread that inlluence around instead of sim-
plv ruling our \ arious niches.

"That last point can't be overemphasized."
he added. "A chair has to be altruistic and
must successfully negotiate the balance be-
tween altruism to the department and com-
mitment to (me\ own programmatic or
scientific interests.

"Finally, this decision v\ as made easier be-
cause I really feel I owe the University of
.North Carolina my career. So the opportunity
to return and give something back to the in-
stitution was a major factor. I'm not sure I
would ha\e taken such an administrative po-
sition at another institution because I would
not ha\ e felt that same loyalty and need."

In terms of a vision for his department. Dr.
Bankaitis sa\ s the title change from Cell Bi-
ology and .Anatomy to Cell and Develop-
mental Biologv rellects the future direction
of the department.

"First of all. biology in general is an enor-
mously exciting field now. With a number of
genomes, including the human genome, se-
quenced, we have access to information we
could onlv have dreamed of just a few years
ago. Tremendous amounts of information
can now be gathered very rapidly. Certainlv
with the enomious genomic science initiative
on campus, and the outstanding qualitv ol the
facultv that have been recmited to Carolina to
direct this effort, there's no question that ge-
nomic science will become a real strength at
this university.

Btinkiiitis examines yeasi inutants engineered Jor dejeets in o novel lipid-nieditaled sigmiling pathway
diH-overed hv his lab.

Dr. Bankaitis pointed out that cell biology
interfaces with every other field, including
genetics, developmental biology, genomics
and proteomics. biochemistry, structural bi-
ology and chemistry. "And I think most will
agree that the best and most exciting science
is done at the interface of different fields."

Dr. Bankaitis believes that scientists who
fit his recruiting profile, particularly those
who work in simpler and genetically
tractable model systems - yeast, w orms and
Drosophila. tor example - will be very suc-
cessful in nav igating the post-genomic era.

"These model systems will continue to
offer a real advantage in this arena because
complex pan-genomic questions can be ad-
dressed more readily in these systems, and
we can more readily discern the patterns." he
says.

"Moreover, the post-genomic era will
bring the experimentalist back to front and
center When we've collected the data, when
we've categorized the genes, when we've
generated the expression profiling databases,
then we'll still have to answer the basic ques-
tion. Well, how does this all work'.'' Model
systems will continue to make pioneering
contributions there. Obviously, translation of
what we learn from model systems into the
mammalian context will be key."

In making the job offer to Dr. Bankaitis.
William Marzlufl. PhD. executive associate
dean tor research, knew he was going alter a
ver\ sjiecial individual.

"He's extremely successful and energetic.
Vytas is a verv broad scientist, from genetics
to structural biologv. We anticipated that he'd
interact sisinificantlv with our (iciKimics Sci-

ence Center and Neuroscience Center. And
he'll be very effective at recruiting people
here."

Dr. Bankaitis has already signed aboani
three outstanding scientists: Andrew Monis
from the State L'niversity of New York at
Stony-Brook: Patrick Brennwald from the
Weil Medical College at Cornell University:
and Douglas Cyr from the University of .Al-
abama at Bimiingham.

■'.All three scientists are coming in at the
associate professor level and all three have al-
ready established strong inleniational reputa-
tions. I think the department is off to a Hying
start in faculty recruiting." Dr. Bankaitis said.

Now back in Tar Heel country, the father
of two sons and a daughter, his wife a family
practice physician, pays tribute to a depart-
ment that has recently passed through some
hard times.

"The Department of Cell Biology has had
to overcome much adversity in the last sever-
al years. The necessarv renovations of it's
home. Taylor Hall, were enormously dismp-
tive to the research and teaching efforts of the
faculty and posed a serious challenge to de-
partmental morale. Yet, the faculty and staff
showed great resilience, as did the graduate
students and postdoctoral trainees. Faced
with adversity, they all stepped up, dis-
charged their responsibilities, and main-
tained an env iable espirit de corps. The
efforts of these manv people is going to pay
big diviilends for the entire department, in-
cluding lor the new chair. I'm looking for-
ward loe\citin<j limes."

News
Briefs

Radiology residency
ranks high

The American Board of Radiology recent-
ly ranked UNC's radiology residency pro-
gram fourth in the United States out of 196
programs based on the percentage passing
rate on specialty oral exams by first-time
UNC takers in the last five years.

American Chemical
Society names 2001 NC
Distinguished Lecturer

Aziz Sancar, MD,
PhD. Sarah Graham
Kenan Professor of
Biochemistry and
Biophysics at UNC,
has been named the
2001 Distinguished
Lecturer by the North
Carolina Section of
Sancar the American Chemi-

cal Society. Sancar. a graduate of Istanbul
School of Medicine in Turkey, joined the
UNC faculty in 1982, five years after obtain-
ing his PhD from the University of Texas at
Dallas. His research interests lie at the inter-
face of chemistry and molecular biology. He
has published over 200 articles in the field of
DNA repair. His research group discovered
the pigment in the human eye called cryp-
tochrome. which regulates the biological
clock. The annual NC-ACS award recog-
nizes an individual who has made a distin-
guishable contribution to the chemical
sciences.

UNC Pair Named
Burroughs Wellcome Fund
Award Winners

Two Carolina faculty are winners of the
Burroughs Wellcoine Fund New Investigator
Awards in the Phannacological and Toxico-
logical Sciences. David P. Siderovski. PhD,
assistant professor of pharmacology and
Mohanish P. Deshmukh, assistant professor
of cell and developmental biology, each will

Siderovski

Deshmukh

receive $210,000 over three years, beginning
July 1, 2001. Both are members of UNC's
Neuroscience Center. Carolina is the only
university in this round of awards to have
won in both categories. The awards, which
began in 1998, recognize the importance of
the fields of pharmacology and toxicology to
huinan health and are aimed at fostering the
development of scientists early in their ca-
reers. This is the final year for these awards.

20 percent hike in NIH
research funding places UNC
13th among private, public
universities nationwide

National Institutes of Health funding for
research at the University of North Carolina
at Chapel Hill jumped more than 20 percent
in fiscal 2000. according to new figures just
released by the federal agency.

UNC faculty received $207 million in
NIH funding — up from $171.3 million in
1999 — ranking 13th overall among private
and public universities nationwide, and up
from 14th last year. Johns Hopkins Universi-
ty topped the list at $419.3 million. Carolina
is the top public university in the South and
one of only five Southern universities, public
or private, cited in the NlH's top 20.

The NIH, part of the Department of Health
and Human Services, is the principal bio-
medical research arm of the federal govern-
ment. NIH research institutes are fighting
diseases including AIDS, alcoholism, aithri-
tis, cancer, diabetes and stroke, as well as
tackling health topics related to aging,
women and children, drug abuse, the envi-
ronment and rapidly emerging multidiscipli-
naiy fields such as genomics and proteomics.

The School of Medicine received $144.2

million, ranking 15th nationwide. Dr Jeffrey
Houpt. dean of the medical school, said the
almost $13 million increase in medical
school funding from fiscal 1999 to 2000
would have strong implications for UNC's
new genome .sciences initiative.

UNC Chancellor James Moeser recently
announced a public-private investment in a
campuswide genome sciences initiative rep-
resenting at least $245 million over the next
decade. Grants to the School of Medicine
from sources including the NIH accounted
for more than $ 1 0 million of that total.

Houpt said he had seen what a difference
the NIH's 1999 selection of UNC as one of
two Regional Mutant Mouse Resource Cen-
ters in the nation made in genetics and ge-
nomics research. The new center, supported
by a $5 million NIH grant, helps character-
ize, maintain and distribute an ever-growing
array of mutant mouse models to the research
coinmunity.

"This strong NIH funding gives the uni-
versity crucial resources to further elevate re-
search efforts and provides further validation
that we are poised to become a national
leader in genomics-related research," he said.
"The discoveries in genomics made in
Chapel Hill will ultimately benefit the people
of North Carolina and the world, who will
hve better lives because of our faculty's dedi-
cation."

UNC's $207 million NIH funding total in-
cluded 484 research grants worth $ 1 76.4 mil-
lion, 43 training grants totaling $10.5
million. 30 fellowships worth close to $ 1 mil-
lion, 14 research and development contracts
valued at $17.2 million and six other awards
worth $2 million.

All five of UNC's health affairs schools —
dentistry, medicine, nursing, pharmacy and
public health — ranked within the top 25 of
public and private institutions, according to
the NIH. Three UNC schools were listed at
fifth or higher Following are the NIH totals
for all five schools;
•The School of Dentistry received $8.4

million, third nationwide.
•The School of Nursing received $5.3

million, third nationwide.
• The School of Public Health received $28.8
million — more than doubling the 1999
total of $ 1 3.2 million — fifth nationwide.

Luncheon honors
volunteers

Tlwaninial Volunteer Senice Award
luncheon was held recently and
honored Anne Wright, a volunteer
in UNC Hospitals emergency
departmeiit. Wright was given
the Elaine M. Hill Award for
Distinguished Volunteer Senice.
which included an engraved clock
presented by UNC Hospitals
President Eric Munson. Tlie event
also recognized volunteers who
sened more them 500 hours in
the past year

Eric Munson and Anne Wnvht

• The School of Medicine received $ 1 44.2
million, ranking 15th nationwide.

• The School of Pharmacy received $ 1 .5
million, ranking 24th nationwide.

Dr. Linda Dykstra. interim vice provost for
graduate studies and research, said the close
to S36 million increase in o\erall NIH re-
search funding had strong implications for
the future of faculty research at Carolina.

Fiscal 2000 overall research funding at
UNC topped the S.375 million mark for con-
tracts and grants awarded for research, teach-
ing and public service — an increase of 9
percent over the previous fiscal year. The
components making up that total are the fol-
lowing: S.316 million for research. $\5 mil-
lion for training. $4 I million for public
service and S4 million for operations.

In academic affairs, several units regis-
tered significant gains in overall research
funding. Examples include Kenan-Flagler
Business School, whose funding increased
from S2. 1 million to S4.6 million, and the
School of Social Work, whose funding in-
crea.scd from S7.6 million tt) SI 1 .6 million.

"Our faculty members are to be com-
mended for their hard work and innovation,
beautifully articulated through their research
efforts." she said. "Our wonderful research
funding numbers point to the professional
and academic strengths of our faculty and en-
sure that we will further strengthen our na-
tional leadership within the world's
promising research areas."

Dykstra added that UNC faculty further
establish their leadership through their affili-
ation with prestigious national academies, in-
cluding: eight members of the National
Academy of Science, five members of the
National Academy of Engineering. 20 mem-
bers of the Institute of Medicine and 16
members of the American Academy of Arts
and Sciences.

Last fall's passage of the $.3.1 billion bond
referendum for higher education will signiti-
cantly improve space in w hich faculty con-
duct their research, through repair and
renovation projects, as well as construction
of new buildings. Dvkstra said.

Health Sciences Library
to present Netter exhibit

The UNC Health Sciences Library will ex-
hibit draw ings of the human body by Frank
H. Netter. MD, Oct. 6-Dec. 3 1.

Netter, who has been heralded internation-
ally as one of the foremost medical illustra-
tors of the 20th century, dedicated his
lifetime to producing thousands of drawings
of the human body. v\hich portray complex
medical anatomy, human pathology, and the
intricacies of physiological processes. Each
finished plate highlights the essential details
of the subject being covered and crystallizes
the concept for the \iewer, making his illus-
trations equally \aluable to the fledgling stu-
dent and seasoned practitioner alike. Netter's
training as an artist and a physician, as well
as the intense research process he conducted
for every drawing, resulted in an accuracy
and attention to detail unsurpassed in med-
ical illustration.

The library's "Legacy of a Lifetime" ex-
hibit will follow Netter's path as an icon of
medical illustration, from his early training
as a commercial lulist to his most prominent
project, the CIBA Collection of Medical Il-
lustrations. Resource materials from the
Health Sciences Library's Frank H. Netter,
MD, Collection will illustrate the research
process Netter conducted to produce his
drawings, including the preliminary pencil
sketches he used as the basis for the final
plates in the CIBA volumes and the clinical
symposia series.

The collection, donated to the library by
Netter's daughter. Francine Netter Carlson,
includes handwritten lecture notes and per-
sonal reminiscences of his projects
and liav els.

13

Alumni Profile

Incoming president feels urge
to give back to alma mater

ByBernadetteGillis

Who knew spending time in a prison
could lead to such a rewarding career?

When Thomas J. Koontz. MD. entered the
School of Medicine, he thought he was inter-
ested in cardiology, but after performing
surgery at Central Prison in Raleigh as a
third-year resident, he knew exactly how he
wanted to spend the rest of his life.

"I was just attracted to surgery. The tech-
nical aspects of it enamored me." He added,
"From then on. I never looked back."

Koontz, class of 1 966, always felt sure he
would go into medicine, even though he
wasn't always certain of the specialty.

Koontz grew up in Welcome, N.C., where
his next door neighbor, a physician, influ-
enced his love of medicine early on. "I think
observing him as he worked with people in
our small community and sensing the respect
people had for him motivated me to become
a physician myself."

After becoming a surgeon, Koontz found
himself caiing for the man who inspired him.
Koontz said that when his former neighbor
became ill, it meant a great deal to him to be
able to provide care. "When 1 cared for him,
it all came full circle."

Once he left the School of Medicine.
Koontz completed his general surgery resi-
dency at Yale University and then joined the
Air Force in 1971.

Following his stint in the Air Force.
Koontz found himself close to home when
he joined the staff at Forsyth Medical Center
in Winston-Salem, where he was able to give
back to his own community. He has served
on the boards of trustees of Forsyth Medical
Center and Medical Park Hospital continu-
ously for the past 2 1 years.

In 199.^, when he was president of the
Forsyth-Stokes-Davie County Medical Soci-
ety, he helped implement a program for the

Thomas J. Koontz. MD, '66. addressed alumni at the animal Distinguished Service
Awards and Distinguished Facidty Award banquet.

working poor. ""I had been in practice for so
long, and I kept seeing working people come
in with no medical insurance. They would be
financially devastated by their illness."

Koontz urged his colleagues at Forsyth
Medical Center and N.C. Baptist Hospital

to start Doctor's Care, a program to provide
care to people who make too much money
to receive government assistance but are not
able to afford heath insurance. The program
provides patients with free physician
visits, as well as free hospitalization and

Thomas J. Koontz, MD

Age: 60
Wife: Lynne

Children: Jeff recently graduated
from Tulane Law School in New
Orleans: Jennifer lives in Atlanta.

Personal interests: Skiing, golf,
tennis, traveling and gardening.

surgeries if indicated.

"It was a program that needed id be started
for those who fall through the cracks."
Koontz said.

The program, which has offered $5 mil-
lion worth of free care to Forsyth County res-
idents since its inception, gives patients
peace of mind in addition to the care they
need. Recently. Koontz pcrfonned a colecto-
my on a patient v\ ho. without Doctor's Care,
would have faced a large bill that would ha\e
been difficult for her to pay. "She and her
family were so appreciative of being able to
ha\ e the surgery." Koontz said.

And recei\ ing appreciation from the pa-
tients is what makes undertaking the program
worthwhile. Koontz added. "Thai's bellei
than getting a check in the mail."

More and more medical societies are get-
ting in\olved with community programs,
such as Doctor's Care, he said. "It gi\cs us a
chance to give back to the community. Doc-
tor's Care has worked out nicely."

Koonl/'s dedication to his eommunity and
to Forsyih Medical Center has been evident
for years. In 1980 he and some of his col-
leagues saw that Medical Park Hospital,
which was privately owned, was about to be
sold to a for-profit hospital chain. Koontz
con\ inced his surgieal colleagues to get to-
gether to buy the hospital. "Ii\ery body stood
up and fought for the hospital because we

Koontz. (iiul his wife. Lyniii'. iitU'iulccI llic recent Alumni Weekend activitii

didn't want it to get out of local hands."

Even though Koontz has close ties with
Welcome and Winston-Salem, the former
Tar Heel hasn't forgotten UNC. As the new
president of UNC's Medical Alumni Associ-
ation. Koontz hopes to help raise as much
money as possible, but said increased alumni
participation will be the key. "If everyone
gets involved, it's amazing how much good
we can do."

Koontz and his fonner classmates showed
how coming together as alumni could make a
difference. Koontz said he recently attended
his 3.'^th class reunion, and his classmates
contributed S.^8.^.(KH) to the Loyalty Fund.

Koontz has been in\()l\ed with the Med-
ical Alumni Association for many years. He
also has been involved with other areas of the
University, including ser\ice on the Board of
Visitors and as chairman of the Forsyih
County Morehead Scholarship Committee.
Koontz said he has always lound ways lo
gi\e back, both financialls ami ihnnigh his
time.

"It's very important for me to have ties
w ith the School of Medicine." he said. "1
feel I have a debt I need to pay to the
medical school for the privilege of becoming
a physician."

Development
Notes

Woodard

Sabra A. Woodard, MD '76
Supports Endowment
Campaign

Dr. Sabra A.
Woodard is grateful
for the scholarship
support she received
as a UNC medical
student in the 1970s.
Then a divorced
mother of two small
children, the North
Carolina native relied
on scholarship aid and
loans to help with everything from childcare,
to tuition, to the utility bills in married student
housing.

Today, Woodard is a radiologist with a spe-
cialty in nuclear medicine at Rex Hospital in
Raleigh. A 1972 UNC undergraduate and a
member of The UNC School of Medicine
Class of 1 976. Woodard recently began mak-
ing gifts to the Loyalty Fund. This year, while
celebrating her class's 25th reunion, she start-
ed thinking. "I realized that I enjoy a wonder-
ful job and a very secure future because I was
able to get educated in medicine with the help
of scholarships," she said. "I never want to
forget what the medical school did for me.
and that's why I wanted to give something
long-lasting back to the university."

So Woodard decided to make a major com-
mitment to the School of Medicine through
the Medical Alumni Endowment Campaign.
She has established The Sabra Alderman
Woodard, MD, Loyalty Fund Scholarship
with a 1 0-year pledge of $ 1 00,000, and has
even added the endowment fund to her will.

"T know that there are other people who
would make really good physicians, but they
may not have the money," said Woodard, now
a mother of three and a grandmother. "And I
know that the cost of medical school in
Chapel Hill is going up over the next few
years. I just want to make sure that there are
funds for people like me who couldn't have
gone to medical school otherwise. I hope this
helps other people start thinking about doing
something similar, because it gives the uni-
versity a lot of flexibility and stability."

Grisham Professorship to
Serve as Legacy for Pathology

Grisham

For over a quarter century, Joe Grisham,

MD, served as the
distinguished and
popular leader of the
Department of

Pathology and Labo-
ratory Medicine, dra-
matically expanding
its service responsi-
bilities, research en-
terprise, and teaching
activities. As depart-
ment chair from 1 973-99, his vision and
leadership brought about the union of pathol-
ogy and hospital laboratory medicine at
UNC. He broadened the research accom-
plishments of the department, dramatically
increasing NIH funding during his tenure. A
dedicated teacher, he expanded graduate ed-
ucation opportunities and strengthened the
residency training program to make it one of
the best in the nation.

And he did it all while serving as an out-
standing role model, said his successor,
Charles Jennette, MD. "Even when he was
burdened with administrative responsibili-
ties, Joe always maintained an active role in
teaching and paiticipated in the service activ-
ities of the department. He led by good exam-
ple."

Dr. Grisham, a Tennessee native who is in-
ternationally recognized for his research on
the pathogenesis of liver cancer and the role
of liver stem cells in health and disease, has
remained an active and valuable member of
the department even after stepping down as
chair. He is still a full-time faculty member
and Kenan Professor of Pathology and Labo-
ratory Medicine. During the 1 999-2000 aca-
demic year, he was awarded a prestigious
Fogerty Scholarship to pursue research at the
National Cancer Institute.

To honor his many contributions and to en-
sure that UNC will continue to benefit in his
name, his department and admirers have
launched a fundraising campaign to create
The Joe Wheeler Grisham Distinguished
Professorship in Pathology and Laboratory
Medicine. The goal of the campaign, which
was launched in November, is to raise over
$500,000 to pennanently endow this profes-
sorship.

The endowed professorship will be a last-
ing legacy to Dr. Grisham that will help en-
sure that the department continues to
maintain the excellence from which all cur-
rent and former faculty and trainees have

benefited. The department seeks to raise
$400,000 in private contributions, which will
secure additional matching funds from the
legislature that will allow this professorship
to have an even greater impact. All donors
will be recognized in the Medical Founda-
tion's Donor Report, released in the fall
of 2001.

The honor of the title and the added finan-
cial resources that will be available to the
holder of the Grisham Professorship will
help the department recruit or retain an out-
standing faculty member with the potential to
contribute to UNC in ways similar to those in
which Dr. Grisham has contributed. Dr. Jen-
nette explained. And because the professor-
ship is not constrained to any one area of
research or service, the department will have
the flexibility to choose an outstanding can-
didate in any area of pathology.

Earl Jenkins, MD. ("77), a pathologist in
Rock Hill, S.C, who trained under Dr. Gr-
isham in the 1970s, was pleased to be named
one of the tri-chairs for the campaign. "I am
participating for three reasons. First, because
of my appreciation of and my pride in the
University of North Carolina School of Med-
icine and the entire UNC-Chapel Hill facility
as a cornerstone of my professional career
and success. Second, out of my respect for
Dr. Grisham as chair of the Department of
Pathology during my resident years and his
support and confidence in me as both a resi-
dent and chief resident. And third, my sup-
port of Charles Jennette as current chairman
and my desire for continued excellence in
pathology training and research at UNC."

If you would like to contribute to the The
Joe Wheeler Grisham Distinguished Profes-
sorship in Pathology and Laboratory Medi-
cine, contact Mary Ollila of The Medical
Foundation of North Carolina Inc. at (800)
962-2542.

Grisham Professorship Steering
Committee

Tn-cluiirs

John Benson. MD '83
Jim Maynard, MD '76
Earl Jenkins. MD '77

Committee members

Walt Avery, MD '68

Wallace Baird,MD '73

Ron Edwards, MD "65

Jane Lysko-Isbey, MD "86

Charles Jennette . MD '75 Ad-hoc member.

department chair

16

Loyalty Fund Campaign kicks off

Class of 2001 Loxdlty Fund Campaiiiii co-chairs Robert Marshall and Priya Rajan
{front row center} are shown with Robert Bashford. MD. '71 (seated far left), recipient
of the first Medical Alumni Distinguished Teaching Professorship, and members of the
Steering Committee at their organizational meeting in March.

Elizabeth Amend is now the associate di-
rector of de\ elopment at the Bowles Center
for Alcohol Studies. Amend will focus on
providing information about Center research
programs to those in the community and
around the country. She will identify and in-
terest people concerned about the destructi\ e
effects of alcoholism in their families,
friends, workplace and society. Her work
will combine educational activities and out-
reach.

Ainend will work to involve both old and
new friends of the center in campaigns to
sustain and e.xpand research and treatment
programs. Her efforts will unite those who
want to invest their time and resources in the
acti\ ities of the center.

A native of North Carolina. Amend, has
man\ links to UNC. In 1991. she worked on
special projects for UNC Playmakers theatre.
She joined the UNC School of Medicine
Arthritis Center in 1995 to build a research
development program and successfully
raised several million dollars for arthritis re-
search.

Phifer Cnite resigned her position as se-
nior development officer for the N.C. Chil-
dren's Hospital to assume the role of Director
of Donor Relations at the Medical Founda-
tion. In her new position. Crute focuses on
prov iding stewardship activities for major
donors to the School of Medicine and UNC
Hospitals.

Crute. a N.C. native, has worked in devel-
(ipment for more than 10 years, including for
the N.C. Museum of Art and Carolina Ballet.
She has worked with the foundation for five
years, and is a 1 9X9 graduate of UNC.

Crystal Hinson joined the Department of
Psychiatry in August 1 999 as director of de-
velopment and public relations. In her cur-
rent role, she is responsible for the
Department of Psychiatry's fundraising,
volunteer activities, alumni events and public
relations. She also coordinates activities be-
tween the department of psychiatry and The
Medical Foundation of North Carolina, Inc.

Hinson received her bachelor's degree
from the University of North Carolina and
went on to complete her master's degree at
Appalachian State University. Prior to her
work at UNC, Hinson lived in Boone, NC,
where she served as Director of Develop-
ment for the College of Fine and Applied
Arts at Appalachian State. Hinson resides in
Durham. NC. and enjoys traveling and vdI-
unteering in her community.

(ireg HoIlida> joined the staff of the
Medical Foundation in January as senior de-
velopinent officer for UNC Children's Pro-
grams. Greg will serve as the primary fund
development officer for the N.C. Children's
Hospital.

Holliday comes to Chapel Hill from Ashe-
boro, where he was director of special events
for the North Carolina Zoological Park. A
native of Indiana, he received a bachelor of
arts degree from Butler L'niversity in Inili-
anapolis. where he studied fashion merchan-
dising and marketing. Holliday spent Ivmi
years in the fashion industry working be-
tween offices in Indianapolis, and New York.
He then obtained a position as marketing di-
rector with a major shopping center develop-
er, where he managed marketing and
advertising programs at various shopping
centers in the southeast.

In his new position. Holliday will work di-
rectly with the Department of Pediatrics and
the N.C. Children's Hospital to satisfy a
growing interest in fund raising special
events. He has already dedicated time and
energy to the UNC Dance Marathon and just
w rapped up w ork on the 1 3th .Annual Ciu-oli-
na Kids Classic and the Sev enth Annual Eric
Montross Camp, both held in June.

Mary Ollila is now a senior development
oftlcer at the Medical Foundation and w ill
work with Special Projects. As senior devel-
opment officer, she is focusing on the Med-
ical Alumni Endowment Campaign, a $7
million initiative. Ollila is working with Jane
McNeer. the Medical Foundation vice presi-
dent, to obtain major gifts from alumni to
endow scholarships, professorships and
grants. So far just over $3 million has been
raised. Ollila is also working with Dr.
Charles Jennette on the Grisham Professor-
ship for Pathology.

Ollila graduated from Miami Univ ersity in
Oxford. Ohio, in 1986 with a bachelor's de-
gree in systems analysis with a special inter-
est in production and operations
management. After graduation, she moved to
Columbus to work for Ernst & Young as an
infomiation systems consultant. In 1989 she
shifted careers into development, working in
the leadership and major gift fund-raising
area for the United Way of Franklin County
in Columbus. In 1995 she moved to Los An-
geles, where she continued her career with
United Way as vice president. In 1998 Ollila
moved to Chapel Hill working as a consul-
tant.

Stephanie C. Stadler has moved from
Medical Alumni Affairs to the Medical
Foundation. She is now senior development
officer and will focus on raising unrestricted
funds from medical alumni for the Loyalty
Fund.

Stadler will co-manage with Brent
Thomas 1 1 class reunion campaigns and
nine county area campaigns. She will work
with the volunteers associated with cam-
paign committees, which work to receive
support for student scholarships/prograins,
distinguished teaching protessorships. the
Health Sciences Library and other areas of
identified need within the School of Medi-
cine.

Stadler. a graduate ol UNC, has worked in
the Medical School for several years, includ-
ing eight years as assistant to the associate
dean for clinical affairs. For the last 1 1 years,
while serving as executive assistant, she
managed programs support by the Medical
Alumni Loyalty Fund in the office of Med-
ical Alumni Affairs.

17

Annual banquet offers
kudos for service

Lori and Ken Blcin. MD. '81

Darlxne Menscei: MD.'79. and Marvin McCalL MD,'56. a DSA recipient.

Bohbx Rimer. MD. a DSA honoree.

Charles Sawyer 111. MD.'63. right, a DSA recipient, chats with Ernest Craigc. MD.

Dean Jeffrey Hoiipl. MD. left, and Paul Viser. MD. 'S4. rif^ht. pose witli volunteer leadership of the Loyalty Fund county and class
campaigns for 2000-01.

Ira Ahrahaiiison. MD. '46. accepts his DSA
recognition.

(leor^e I: Sheldon. Ml), left, this \ear'\
Distinguished liu ult\ Award rec Ipicnt. t(dLs
with former Dean Stuart iioiulurant. MD.

G. Philip Miintrc. PhD. sits with DSA wiimcr Lucia Hudson.

19

Match Day 2000

On March 22 - "Match Day" - 155 grad-
uating medical students at the Universi-
ty of North Carolina at Chapel Hill learned
where they will spend the next several years
completing their residencies.

This year. 83 percent of UNC-CH med-
ical students were matched with one of their
three top choices during the computerized
process compared with 85 percent national-
ly. Sixty-three percent received their first
choice, compared to the U.S. average of 60.5
percent. From UNC, 9 percent are entering
first-year placements in family medicine, 20
percent in internal medicine, 1 .3 percent in
medicine-pediatrics, 1 1 percent in OB/GYN
and 12.3 percent in pediatrics.

Match Day is eagerly anticipated by the

graduating students, who bring their parents,
spouses, children and friends with them to
celebrate their good fortune or, in fewer
cases, commiserate their disappointment.

"As a group, our students are incredibly
accomplished and talented people, and
Match Day is just one more manifestation of
their achievements," said Georgette A. Dent,
MD, associate dean for student affairs.

Match Day is organized by the National
Resident Matching Program, a private, not-
for-profit organization sponsored by the
American Board of Medical Specialties, the
American Medical Association, the Associ-
ation of American Medical Colleges, the
American Hospital Association and the
Council of Medical Specialty Societies.

Anesthesiology

Christie. Angus Andrew
UNC Hospitals. Chapel Hill

Costabile. Sean Vincent
Vanderbilt Univ Medical Ctr.
Nashville, Tenn.

Hauser. Justin Bradley
UNC Hospitals, Chapel Hill

Javelona. Thomas L P
UNC Hospitals. Chapel Hill

Marshall III. Robert Nelson
UNC Hospitals. Chapel Hill
McDevitt, Michelle Leiah
UNC Hospitals. ChaperHill

Sair. Farrukh Iqbal

Hosp of the U of Pennsylvania,

Philadelphia

Schlichter. Rolf Alexander

U Penn Health Systems/Presby,

Philadelphia

Tsai, Tony Potung

St Lukes - Roosevelt Hospital Center.

New York

Williams-Toone. Deitra L
Wake Forest U Baptist Med Ctr.
Winston-Salem

Dermatology

Hangman. William Leo

Duke University Medical Center.

Durham

McLeod. Tonya S

Emory University School of

Medicine. Atlanta

Emergency Medicine

Bates. Craig Guy
MetroHealth Medical Center.
Cleveland. OH

Lavenhouse Jr. Clifton
UNC Hospitals, Chapel Hill

Look. Rodney Bryce
Brigham & Women's Hospital.
Boston

Overcash. Jeffrey Scott
UNC Hospitals. Chapel Hill

Peck, Clifford Robert
Maine Medical Center,
Portland, Maine

Family Practice

Barrett, Elizabeth Grier

Thomas Jefferson University.

Philadelphia

Bullard, Tracy Elizabeth

Southern Regional AHEC Earn Res

Fayetteville, N.C.

Dear, Janet Kidd

Duke University Medical Center.

Durham

Graham, Jenny Leigh

Montana Family Practice Res,

Billings, Mont.

Lee, Tae Joon

Swedish Medical Center, Seattle

Morris. Sequita Magnolia

Anderson Area Medical Center,

Anderson. S.C.

Peele. Lori Diane

Eastern VA Medical School GME.

Norfolk, Va.

Roberson, Jennifer

New Hanover Regional Med Ctr,

Wilmington. N.C.

Ruehsen Jr. Hans J

Maine Dartmouth Fam Prac Res.

Augusta. Maine

Sawin, Shannon Mullis

UNC Hospitals. Chapel Hill

Selph. Shelley Suzanne

U Nonh Dakota SOM & Health

Sciences, Grand Forks. N.D.

Stengel. Deborah Ann

New Hanover Regional Med Ctr.

Wilmington. NC

Sun. Vyvyan Ye-Lin

Trident Medical Center.

Charleston. S.C.

Trost, Melanie Eileen Kirk
Duke University Medical Center.
Durham

Internal Medicine

Abernathv. Elizabeth Ila

UNC Hospitals, Chapel Hill
Baer. Jefferson Tomas
Hosp of the U of Pennsylvania.
Philadelphia

Bishop. Thomas Harman
Wake Forest U Baptist Med Ctr.
Winston-Salem

Bridges Jr. Henry E

York Hospital, York. Penn.

Brown, Christopher G

Ohio State Univ Med Ctr. The.

Columbus. Ohio

Brubaker. Beth Ann

Hosp of the U of Pennsylvania.

Philadelphia

Carrizosa. Daniel R

UNC Hospitals. Chapel Hill

Childress. Donna Reefe

Carolinas Medical Center. Charlotte

Colford. Cristin Mulderig

UNC Hospitals, Chape! Hill

Eifrig Jr, David E

New Hanover Regional Med Ctr.

Wilmington, N.C.

Fangman, William Leo

UNC Hospitals. Chapel Hill

Foster. Michelle Lynette

Carolinas Medical Center, Charlotte

Fried. Daniel Benjamin

New Hano\er Regional Med Ctr,

Wilmington. N.C.

Gage. Jeffrey Andrew

Moses H Cone Memorial Hospital.

Greensboro

Gill, Kristen Teresa

University of Maryland Medical Ctr,

Baltimore, Md.

Gray III. Lee Virdis

Carolinas Medical Center, Charlotte

Ho, Vicki Cathy

UNC Hospitals, Chapel Hill

Hoffman, Mari Allison

New England Medical Center.

Boston

Hsu. Shiao-Wen David

U Texas Southwestern Med

Jensen, Brian Colwell

Brigham & Women's Hospital,

Boston

Kontos, Jimmy Larry

George Washington University

Hospital, Washington

Lee, Bruce Minshik

U Rochester/Strong Memorial.

Rochester, N.Y.

McLeod. Tonya S

Carolinas Medical Center. Charlotte

Miller III, Russell Raymond

University of Virginia,

Charlottesville, Va.

Miller, Alison Nemeth
Vanderbilt Univ Medical Ctr,
Nashville. Tenn.
Morton. Emma Brown
BrighaiTi & Women's Hospital.
Boston

Neuharth, Kristen Lynn
University of Connecticut,
Famiington, Conn.
Scott. Georgia Lea
UNC Hospftals, Chapel Hill

Shimpi. Rahul Arun

Duke University Medical Center,

Durham

Smith, Charles Shiangfei
Brigham & Women's Hospital,
Boston

Sturgill, Stephanie Bialas

UC San Diego Medical Center, San

Diego, Calif.

Taylor. Benjamin Blaine

U Alabama Hospital - Birmingham,

Birmingham. Ala.

Teague. Carmen Icard

Carolinas Medical Center. Charlotte

Timberlake, Rufus Johnston
U Rochester/Strong Memorial,
Rochester, N.Y.

TuUo, Teresa Louise

Moses H Cone Memorial Hospital.

Greensboro

20

Umar. Ramsey Kamel

U Michigan Hospitals, Ann Arbor,

Mich.

Vo, Nam Dai

L'NC Hospitals. Chapel Hill

Medicine - Pediatrics

Juliano. Jonathan J

U Minnesota Medical School.

Minneapolis, Minn.

Mah. May Ling

UNC Hospitals, Chapel Hill

Neurological Surgery

Kilpatnck, Michaux R
L'NC Hospitals, Chapel Hill

Obstetrics/Gynecoiogy

.Alston, Pamela Kaye

Wake Forest U Baptist Med Ctr,

Winston-Salem

.Archie, Anne Bond

Carolinas Medical Center, Charlorte

Bass, Lawrence Adrian

New Hanover Regional Med Ctr,

Wilmington, N.C.

Beatty, Zoe .A

Milton S Hershey Med Ctr Prog.

Hershey. Pa.

Boy. Jennifer Dawn

Hosp of the U of Pennsylvania.

Philadelphia

Di,\on. Melanie Heather

Mayo Graduate School of Med.

Rochester. Minn

Floyd, Serina Eisha

Duke University Medical Center,

Durham

Geller, Elizabeth Joanne

UC Irv ine Medical Center, Orange.

Calif.

Highsmith. .Aquilla Lynette

Keesler .Air Force Base. Biloxi. Miss.

Johnson, Krista L

L'NC Hospitals, Chapel Hill

Kim. John Chae

Palmetto Richland Memorial

Hospital. Columbia. S.C.

Malizia. Beth Anne

L .Alabama Hospital - Birmmgham,

Birmingham, Ala.

Proctor. Asha Kilola

Carolina.s .Medical Center. Charlotte

Rahman, Sameena

L'niv of Massachusetts Programs,

Worcester, Mass.

Rajan. Pnya Varadha

L'C Irvine Medical Center. Orange.

Calif.

Richardson. Chnstin Neal

UC San Diego Medical Center.

San Diego, Calif.

Spruill. Steven Carl

L'niv HIth System - Eastern Carolina,

Greenville. N C

Orthopedic Surgery

B\crl>. faera Ledtord

New England Medical Center.

Boston

Gallagher. Michael Dennis

McGaw Med Ctr Northwestern U.

Chicago

Norcross. Jason Patrick

U Texas Med Branch Galveston.

Galveston. Texas

O'Malley. Aran Marino

LI Tennessee COM - Memphis,

Memphis, Tenn.

Phadke. Parag Madhav

Carolinas Medical Center. Charlotte

Schimizzi. Aimee Lynn

UC San Diego Medical Center.

San Diego. Calif

Toulson, Charles Ernest

Johns Hopkins Hospital. Baltimore.

Md

Otolaryngology

Hardy. Stuart McDowell

UNC Hospitals. Chapel Hill

Heavner. Steven Brett

U Michigan Hospitals. Ann Arbor.

Mich.

Pathology

Carter. Alicia Lynette

UNC Hospitals, Chapel Hill

Falls, Evelyn Louise

Duke University Medical Center,

Durham

Michael, Davonia N Wagner

Wake Forest U Baptist Med Ctr.

Winston-Salem

Pediatrics

Booker, Millicent Candene

Duke University Medical Center.

Durham

Campbell. Cynthia Heather

Carolinas Medical Center. Charlotte

Cinniger. Julia Carmen

U Rochester/Strong Memorial.

Rochester. N.Y.

Cisco. Michael Joshua

UNC Hospitals. Chapel Hill

Cooper. Alan W

UNC Hospitals. Chapel Hill

Forcier. Tara Anne

U Minnesota Medical School.

Minneapolis. Minn.

George. M Susan

Montetiore Medical Center. Bronx.

N.Y.

Greenlee. Cynthia Renee

Univ of Louisville School of

Medicine. Louisville. Ky.

Hoover. Michael Shane
Medical Univ of South Carolina.
Charleston. S,C.
Houston. Shelley Adkins
UNC Hospitals. Chapel Hill

Jackson. Juliana Shawn
UNC Hospitals. Chapel Hill

Lindell. Ken Ann

University of Connecticut.

Farmington. Conn.

McGee. Janey Ruxanna

Univ of Washington Affil Hosps.

Seattle

Partin. Sydney

Duke L'ni\ersity Medical

Center. Durham

Peterson-Carmichael, Stacev

UNC Hospitals, Chapel Hill

Rowe. Elizabeth Sue

Univ of Utah Affil Hosps,

Salt Lake City, Utah

Simon, Tamara Danielle

U Colorado School of Medicine,

Denver

Taylor, Shelly Renee
Medical College of Wisconsin.
Milwaukee. Wis.

Vafai. Radiance Elizabeth
Palmetto Richland Memorial
Hospital. Columbia. S.C.

Physical Medicine & Rehabilitation

Bridges Jr. Henry E
Medical College of Virginia.
Richmond. Va.

Plastic Surgery

Antony. Anuja Kandanatt
Stanford University Programs.
Stanford. Calif.

Harmaty. Marco Andrew
Mount Sinai Hospital.
Nevs York

Psychiatry

Adams. Felicity Ann
UNC Hospitals, Chapel Hill

Baer, Wendy Miles

Hosp of the U of Pennsylvania,

Philadelphia

Benyas, Steven Isaac

Cambndge Hospital/CHA,

Cambridge, Mass.

Cressman, Victoria Lee

New York Presbyterian Hospital,

New York

Gibson. Debra L

UNC Hospitals. Chapel Hill

Gurkin. Brett Alexander

Medical Univ of South Carolina.

Charleston, S.C.

Look, Adair Kendrick
Massachusetts General Hospital.
Boston

Look. Adair Kendrick
Massachusetts General Hospital,
Boston

Navarre II, J Richard
Emory University School of
Medicine, Atlanta

Rich, Susan Diane

Georgetown University Medical Ctr,

Washington

Robertson. Vida Barnwell

LSU Sch of Med - New Orieans,

New Orleans

Schobel. Scott Allan

New York Presbvterian Hospital.

New York

Urakuho. An

I'C S.in Irancisco. San Francisco

Radiology - Diagnostic

Bishop. Thomas Harman
UNC Hospitals. Chapel Hill

Gage, Jeffrey Andrew

Universitv Of South Flonda, Tampa,

FTa,

Wessell, Daniel Edward
Barnes-Jewish Hospital, St Louis,
Mo.

Radiology - Oncologic

Fried, Daniel Benjamin

UNC Hospitals, Chapel Hill

Mitsuyama. Hiroki

Univ of Washington Affil Hosps.

Seattle

Surgery

Bowen, Josie Barnes

Univ Hlth System - Eastern Carolina,

Greenville, N.C.

Bums, Justin M

Carolinas Medical Center. Charlotte

Heavner. Steven Brett

U Michigan Hospitals. Ann Arbor.

Mich.

Houston. Michael Anthony
UNC Hospitals. Chapel Hill

Kelso, Rebecca Lynn
Univ of Southern California, Los
Angeles

Mlinar. Kathryn Jean
UNC Hospitals. Chapel Hill
Mondi. Matthew Michael
Wake Forest U Baptist Med Ctr. Win-
ston-Salem
Smith, David Warner
Univ of Utah Affil Hosps. Salt Lake
City, Utah

Smith, Maurice Antonio
Medical College of Georgia, Augus-
ta. Ga.

Tsai. Tony Potung
Carilion Health System, Roanoke,
Va.

Vincent. Ariel Shoshona
UC San Francisco - Fresno. Fresno.
Calif,

Transitional

.Mukal, Joseph Paul

Boston University Medical Ctr,

Boston

Sedberry, Sherry V

George Washington University

Hospital, Washington

Benyas, Steven Isaac

Cambndge Hospital/CHA,

Cambridge, Mass.

Berghoff, Adar Taun

Ponsmouth Naval Hospital.

Portsmouth. Va.

Mitsuyama, Hiroki

Mercy Hospital of Pittsburgh,

Pittsburgh

Roach, Lalonia Evette

Triplet Army Medical Center

Program, Tnpler AMC, Hawaii

Sair. Famikh Iqbal

Frankford Hospital. Philadelphia

Walker Jr. Vester Wade

Cambridge Hospital/CHA.

Cambridge. Ma.ss.

Wessell. Daniel Edward

Western Pennsylvania Hospital.

Pittsburgh

21

Research
Briefs

New method lets researchers
study heart cell messages

Scientists at the University of North Car-
ohna at Chapel Hill are using a new way to
study how heart muscle cells communicate
electrical and chemical messages.

Researchers may use the new application
to study what happens during or after a heart
attack, when communication between cells
breaks down.

Research Associate Barbara J. Muller-
Borer, Ph.D., and her colleagues in the Divi-
sion of Cardiology at UNC's Department of
Medicine used a technique called fluores-
cence recovery after photobleaching, or
FRAR to study cell-to-cell communication
through tiny tunnels between cells called gap
junctions.

She will present the work at the North
American Society of Pacing and Electro-
physiology conference in Boston on May 4.

"You take a fluorescent probe, load it into
your cells, and shine a laser pulse on some of
them." Muller-Borer said. The laser makes
the probe stop glowing, and the laser-zapped
cells stop glowing.

As the fluorescent probe from surround-
ing cells diffuses in through gap junctions,
fluorescence recovers and the zapped cells
begin to glow again.

"The time it takes for the cell to recover
fluorescence would be an indicator of how
well the cells are coupled," or connected to
each other, Muller-Borer said.

Coupling is important in heart muscle
cells because the electrical signal that causes
the heart to beat travels through them. If they
become uncoupled, you're not going to get
electrical conduction through that tissue, and
the heart will stop beating, Muller-Borer ex-
plained.

Heart muscle cells can become uncoupled
when their oxygen supply is cut off, as hap-

pens during a heart attack.

Other researchers have used voltage-sen-
sitive dyes to study the flow of electrical sig-
nals through heart tissue.

"The problem with some of those dyes is
they're pretty toxic," Muller-Borer said. "So
once you flash the cells with the laser, the
dyes become toxic and the cells die. So you
get one good study and then they're dead."
FRAP allows researchers to study cells over
longer periods oftime. Muller-Borer said.

FRAP is an alternative method to study
cell-to-cell communication.

"The classic way to do these experiments
is with electrical measurements," said Wayne
Cascio, M.D., Associate Professor of Medi-
cine at UNC's Division of Cardiology and
one of the study's authors. "You inject a cur-
rent into the muscle and you measure the
voltage between two electrodes along the
path of that current flow. Gap junctions affect
that \'oltage."

But electrodes are not useful for studying
how gap junctions work at the cellular level.
Cascio said. "So this would provide a way to
look at cell-to-cell communication at the
level of single cells in cultures of heart cells.

"We're also interested in using FRAP to
study how common diseases such as hyper-
tension, ischemic heart disease and heart fail-
ure affect the formation and function of gap
junctions." Cascio added. "The number and
distribution of gap junctions are affected by
these conditions and may contribute to some
of the adverse consequences of these dis-
eases. For this reason, we expect that the
FRAP technique will further our understand-
ing of how cell-to-cell communication con-
tributes to heart problems."

This research was supported by a grant
from the National Institutes of Health and the
American Heart Association.

Steve Baragona

UNC symposium
looks at alcoholism

A symposium on genes and genes delivery
for diseases of alcoholism is attracting an in-
ternational gathering of scientists to the
University of North Carolina at Chapel Hill.

The symposium. May 7-10, is co-spon-
sored by the UNC Bowles Center for Alco-
hol Studies. The National Institute on
Alcohol Abuse and Alcoholism, The
UNC-CH School of Medicine, The North
Carolina Biotechnology Center, and Glaxo-
SmithKline. "Diseases of alcoholism have a
significant genetic component and are very
common because alcohol abuse is so com-
mon." said Fulton T. Crews, professor of
pharmacology and psychiatry and Bowles
Center director. "In many diseases of alco-
holism there is, for example, cell death in-
volving genes and gene pathways. Now we
have some key technologies that give us the
ability to understand these processes and to
eventually intervene in them."

Among recently emergent technologies
are gene chips or microarrays by which
changes in the cascade of hundreds of genes
can be obsened simultaneously during a dis-
ease process. Gene delivery is another com-
plementary set of technologies by which
scientists can change only one gene selec-
tively to determine how other genes are al-
tered 'downstream' of a single gene change
using microarrays.

"With this technology we can investigate
the mechanisms of the pathology or deter-
mine if delivery of a specific gene to cells can
prevent the pathology." Crews explained.

"This symposium brings together the
world's experts on gene delivery and gene
analysis using microarrays with the idea that
these methodologies together will give us the
power to cure diseases of alcoholism."

Among the many speakers are William A.

2001 Graduation

Dean Jeffrey L. Hoiipt. MD. handed on! 164 diplomas at this year's medical school i>raduatioii on May 20 in Memorial Hall.
Other festivities that weekend included the Senior Gala, where senior awards were presented.

Carlezon. Jr. of Hanard Medical School who
has used \ iral-mediated gene deli\ery to
change addictive behavior in animals. R. Al-
dron Harris of the University of Texas has
shown through microarray expression that
many genes in the brains of alcoholics differ
markedly from that of nonalcoholics.

"Our own Ronald G. Thurman. professor
of pharmacology and nutrition, is on the

verge of blocking the oxidati\e stress that al-
cohol causes to the liver, thus curing the de-
velopment of liver fibrosis and cirrhosis."
Crews, said.

"In presentations on fetal alcohol syn-
drome, we have H. Scott Baldwin of Chil-
dren's Hospital of Philadelphia who has
developed strategies of gene delivery to the
fetus. And Kathleen Sulik. professor of cell

and developmental biology and anatomy
here at UNC whose current studies in\olve
agents that block the effects of alcohol on the
fetus, including alcohol-associated birth de-
fects." he added. "There is much in the way
of exciting molecular genomic science under
discussion here."

Les Lang

23

Alumni

Notes

50s

80s

R.J. "Jack" Blackley, MD, CM '53, re-
tired and is now working part-time as a con-
sultant with the N.C. Division of Mental
Health, Development Disabilities and Sub-
stance Abuse Services. He enjoys working
part-time, spending time with family and
friends and is looking forward to the 50th
UNC medical reunion and spring weekend
in April.

60s

Hisashi Kajikuri, MD '60, is a thoracic
and vascular surgeon in Monterey, Calif. He
recently was elected to the board of trustees
of Community Hospital of the Monterey
Peninsula, the Community Hospital Foun-
dation for a three-year term ending in 2004.

70s

Lewis Patrick Warren, MD '76, went to
Duke University for radiology residency in
1986. He has been in Wilmington since
1991. During his spare time, he became a
pilot and has taught scuba diving. He and
his wife Jamie ask you to look them up if
you are near Wilmington. You can contact
him at pwarren@wilmington.net.

Sam Selden, MD '77, has been a dermatol-
ogist in Chesapeake, Va., for 20 years. He is
on the faculty at Eastern Virginia Medical
School, and this year was elected president
of the Virginia Dermatological Society.

Robert W. Patterson, MD '78, was ap-
pointed instructor at the UNC Department
of Family Medicine. He will maintain a full-
time family practice in Sanford, N.C.

R. Lee Jobe, MD '87, is now a partner of
Wake Heart Associates in Raleigh. Along
with his wife Donna, the couple has two
children, Tyler, 10, and Lydia, 5.

90s

Anthony Propst, MD '92, is the director of
reproductive surgery at Wilford Hall Med-
ical Center. In June 2000 he completed his
fellowship in Reproductive Endocrinology
at Brigham and Women's Hospital in
Boston, Mass. He and his wife, Heidi, have
twin daughters, Elena and Isabela, who are
1 8 months old.

Randal P. Bast, MD '93, is a surgeon with
Caldwell Surgical Associates. He would
like to announce the Jan. 12 birth of his son
Isaac Evans Bast. He joins a sister, Kathryn
Grace, 3, and brother Aidan Hunter, 2.

Eileen M. Raynor, MD '93, is the assistant
professor of otolaryngology. She welcomed
her son, Logan Foster on Nov. 1 6.

Tony Herndon, MD '95, lives in Wethers-
field. Conn, with his wife Elena and twins,
Samuel Anthony and Katherine Ellen. He is
pursuing a fellowship in pediatric urology
this year in Indianapolis, Ind., at Riley Chil-
dren's Hospital.

Elena Herndon, MD '95, passed board in
adult psychiatry and is pursuing a fellow-
ship in child and adolescent psychiatry. She
and her husband, Tony, welcomed twins,
Samuel Anthony and Katherine Ellen, on
Oct. 31.

Patrick O'Brien, MD '95, is a fellow in

Musculoskeletal Radiology at Brigham and
Women's Hospital in Boston through June
2001. He is taking a position at Northwest
Imaging in Kalispell, Mont., beginning
in July. He completed his residency in
radiology at the University of New Mexico
in June 2000. Contact him at
jonnypolite@hotmail.com.

Robert C. Miller, MD, '98, recently com-
pleted a term as resident coordinator for
District III of the American Academy of Pe-
diatrics. He served on the board of directors
for the resident section of the AAP and co-
ordinated resident activities for the five
states (Delaware, Maryland, Pennsylvania,
New Jersey, West Virginia) and the District
of Columbia contained in District III.

24

President's
Letter

I would like to congratulate Paul Viser
for his leadership and enthusiasm this
past year as president of our Medical
Alumni Association. 1 have especially
enjoyed his presidential messages in the
Medical Alumni Bulletin. I doubt you will
find me as articulate as Paul.

Those of you w ho were at our annual ban-
quet on April 27 enjoyed a wonderful night of
camaraderie and food. There were o\ er 300
medical alumni present for this gala at the
Morehead Planetarium. I believe everyone
there had a wonderful evening. I could not
help but think about the contrast and the en-
thusiasm of our Medical Alumni Association
versus the apathy of the physicians here in
Winston-Salem.

Another hat I wear in my duties is that of
president of the medical staff at Forsyth Med-
ical Center. We ha\e over 500 physicians on
our staff. Oser the past year my major prob-
lem has been to deal with the apathy of our
staff toward the hospital. Recently we held
our annual retreat in Greensboro at the Grand
Over Resort on a Friday evening and again on
Saturday morning with free golf thrown in
that Saturday afternoon. Nine physicians
turned out for the Saturday morning session.
The reason for that poor attendance is a mat-
ter I w ill probably discuss with you later this
year. Those of you at the Spicer-Brecken-
ridge lecture heard from Dr. Kenneth Lud-
merer concerning the angst relating to
medicine and physicians today.

I relate the above to you to happily contrast
my situation in Winston-Salem with our
Medical Alumni Association. Over the past
years we have enjoyed steady growth in our
loyalty fund, attendance has been good at our
meetings and overall interest is improving
w ith our association. What is the difference?
We have in place a superb internal staff that
does a wonderful job organizing our efforts
both for continuing education and fundrais-
ing. But more iinportantly. I believe, is our
love for this great uni\ ersity and our gratitude
for those professors who have left a lifelong
indelible mark on our lives. We also have the
(Opportunity to continue to renew those
friendships with our fellow classmates and
now physician friends. Next, and most im-
portant, is our opportunity to return the privi-
lege this university gave us by allowing us to
enter and then graduate from our great med-
ical school.

This year. I intend to remind all alumni of
that debt of gratitude we owe this medical
school for the distinct pri\ilege of being a
doctor of medicine. I learned many things
during iny years in Chapel Hill which have
stood ine in good stead in my ciireer as a sur-
geon. Hard work, attention to details and hav-
ing fun are my priorities. I prt)mise to work
hard for you this year but most importantly. I
hope we will all have lots of fun. I look for-
ward to seeing and meeting as many of you as
I can over the next year.

Kfs^-k.

Thomas J. Knoiilz. MD.' 66

CME/Alumni Calendar

July 14 - Chapel Hill

CMOS II Training Conference 2001

July 20-22 - Amelia Plantation, Amelia Island, Fla.

Heart Failure Management 2001

July 28 - East Carolina University - Greenville
CMOS II Training Conference 2001

July 29 - The Carolina Inn, Chapel Hill

Promoting Student Success: Clinical Assessment and Management of
Learning Differences

August 24-25 - White Sulphur Springs. W. Va.

MRNC Board Retreat: Developing Clinical and Socioeconomic

Influences on Quality of Care

Sept. 6-8 - The Friday Center, Chapel Hill

NICHQ/CERTs Autumn Institute

Sept. 8 - Chapel Hill

CMOS II Training Conference 2001

Sept. 21-22 - The Friday Center, Chapel Hill

3rd Annual Herbal Medicine Conference

Sept. 21-23 - Williamsburg, Va.

Ross OB-GYN Society Annual Meeting

Sept. 28-29 - The Friday Center, Chapel Hill

Wound Care Management

Sept. 28-30 - The Friday Center, Chapel Hill

UNC RSRC Clinical Instructor Seminar Series 2001 - Part I

Oct. 5 - The Carolina Club, Chapel Hill

Fall Medical Alumni Weekend CME Course

Oct. 14-16- Renaissance Orlando Resort, Fla.

2001 Orlando Breast Imaging and Digital Mammography Conference

For more information, go to www.med.unc.edu/alumni and
www.med.unc.edu/cme.

Estate Planning Notice

Many individuals would like to make a major gift
to the UNC medical center, but cannot commit
current assets for such a purpose. Through a will,
however, anyone can make a more significant gift
than they might ever have thought possible by
designating a specific sum, a percentage, or the
residue of their estate for the benefit of the medical

To provide a bequest, simply include a paragraph
in your will naming The Medical Foundation of
North Carolina, Inc. as a beneficiaiy. For example:

"I give, devise and bequeath (the sum of$

or ( % of my estate) or (the residue of

my estate) to The Medical Foundation of North
Cawlina, Inc., a 501(C)(3) created to maintain
funds for the UNC medical center with principal
offices located at 880 Airport Road, Cluipel Hill,
North Carolina."

This language creates an unrestricted bequest for
use by the medical center when and where the need
is greatest, or you may specify that your gift be
used for a particular purpose.

For further information on bequests, contact
Jane McNeer at (9 1 9) 966- 1 20 1 , (800) 962-2543,
orjmcneer@email.unc.edu.

Nonprofit Organization

U.S. Postage

PAID

Chapel Hill. NC
Permit No. 24

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School of Medicine, University of North Carolina at Chapel Hill

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Special Report: The gala debut of the new
N.C. Children's and Women's Hospitals

The new N.C. Children's and Women's Hospitals were dedicated Sept. 8 in a grand cel-
ebration. It is truly a magnificent facility. The opening of these buildings will be a tremendous
step forward for the children and women of North Carolina. Because of the significance of
this achievement, I have asked the chairs of our departments of Pediatrics and Obstetrics
and Gynecology to share a few words with us.

We'll hear first from Alan A. Stiles, MD, chair of the Department of Pediatrics:

The new N.C. Children's Hospital Is a magnificent facility built with children and their
families in mind. More important than the building is the opportunity that the physicians,
nurses and other staff have to develop the first true children's hospital in North Carolina. It
is fitting that the new hospital is located at UNC because this is the hospital for the people
of North Carolina, and now the children of North Carolina will also have a place dedicated
to their care.

Many people don't know that the majority of care provided for children at UNC is for
very complicated diseases requiring highly specialized care. The hospital's staff includes all
the pediatric and pediatric surgical sub-specialists, specialized nurses and other caretak-
ers. They make up multidisciplinary teams to care for our complicated patients. The new
facilities allow us to expand state-of-the-art, high-technology care while providing patients
and families with child-focused, family-centered care and "one stop shopping." Also, with
the excellent research going on at UNC, we can move quickly to take the new laboratory
findings and bring them to our patients. Children and adolescents in our state will finally
have a place where our excellent staff can deliver care in an environment that will be less
intimidating and oriented to their needs.

Next we hear from Valerie M. Parisi, MD, MPH, chair of the Department of Obstetrics and
Gynecology.

The Department of Obstetrics and Gynecology has a long and proud tradition of pro-
viding cutting-edge care, serving all the women of our great state and beyond. We have a
magnificent health care team to serve women in a creative management scheme involving
the integration of physicians, nurses and hospital and medical school leaders to provide
optimum patient-focused care.

Now with the new Women's Hospital, we can provide facilities to match our team's
expertise. We can also focus on family-centered maternity care, women's wellness and dis-
ease prevention education. Our new hospital was designed to promote patient convenience,
choices and shared decision-making, and is sensitive and respectful of women's life stage,
lifestyle and family issues. The design provides the highest level of comfort and privacy for
women and their families at these stressful times. We mirror the Medical School's "bimodal"
characteristics: strengths in the care of the complex patient and the ability to provide "low-
tech, high-touch" primary care.

It Is no surprise that U.S. News & World Report ranked us 10th in the nation in gyne-
cology. Our new hospital has a dual mission of providing cutting-edge, high-tech disease
management and promoting holistic, humanistic, patient-focused health care relationships,
which will give all the women of North Carolina a level of health care unequaled by any other
center.

I am proud and humbled by this magnificent achievement that reflects so many peo-
ple's visions and holds the promise of caring for women for life.

Jeffrey L. Houpt, MD
Dean, School of Medicine
Vice Cfiancellor for Medical Affairs
CEO, UNC Health Care System

contents

SPECIAL REPORT

N.C. Children's & Women's Hospitals opening 2

FEATURES

Dr. Drake: Craniofacial director brings lifelong UNC ties to
new position 10

Dr. Crocker: The Music Man — Rocky Mount physician
focuses on patients and culture 12

Incorporating faith into practice and precepting 16

New imaging system revolutionizes work, patient service 18

2001 -02 Loyalty Fund Scholars 24

Loyalty Fund Campaign 26

Report to Donors 27

A LONG HERITAGE p.10

THE MUSIC MAN p.1 2

DEPARTMENTS

From the Dean Inside Front Cover

Special Events 15

Alumni 20

Research 21

Faculty 22

From the President 40

CME/Alumni Calendar Inside Back Cover

on the cover

NEW IMAGING SYSTEM p.1 8

N.C. Children's and Women's

More than 1,500 people turned out
SepL 8 for the gala dedication of tfie
new N.C. Children's and Women's
Hospitals. A special report begins on
page 2. (cover photo by Brian Strickland)

The Medical Alumni Bulletin is puWished tour tines annually t)y the UNC-Chapel Hill Medical Alumni Association, Chapel Hill.
NC 27514. ftBbge is paid by the non-ptofit association through US. Ftetal Peimit No. 24. Address correspondence to the ed-
itor, Olfi(» rt Medical Center Put* Affairs, School of Medicine. C8#7600, IJnKiwsity ol North &^^^

Medical Alumni Association
Officers

President

Thomas J. Koontz, l\/ID '66
Winston-Salem

President-Elect

Ray t^^. Hayworth, MD '62
Knoxville, in

Vice President

John W. Foust, fylD '55
Charlotte

John M. Herion, MD '83
Wilmington

Treasurer

William M. Hemdon. Jr., MD '81
Charlotte

Editorial Staff

Karen McCall

Vice Pres. Public Affairs & Marketing

Lynn Wooten

l^anaging Editor

Dick Broom, Leslie H. L,ang,
Bemadette Glllis, Relieluih Butler,
Katharine Savage

Contributing Writers

Jay Mangum, Brian Striclcland

Photographers

The public gets its first iooi( at tlie new
N.C. Cliiidren's and Women's Hospitals

Senator John Edwards

)y Dick Broom

Finally, the great arrival has
occurred. After five years of painstaking
construction, a crowd estimated at more
than 1 ,500 people turned out in Chapel
Hill to see the new N.C. Children's
Hospital and N.C. Women's Hospital.

'This is a historic day for UNC Hospitals and for the women and children of North
Carolina," Eric B. Munson, president and chief executive officer of UNC Hospitals, said at the
Sept. 8 dedication celebration.

U.S. Sen. John Edwards of North Carolina, whose son Jack was delivered at UNC
Hospitals over a year ago, was the dedication's keynote speaker.

"One of the t>est hospital systems just got even better," Edwards told the crowd.
'These new women's and children's hospitals will enable us to make enormous strides
toward better quality health care - for all 100 North Carolina counties, and for the more than
2,500 new Tar Heels, like my son Jack, who start their lives at UNC Hospitals each year."

North Carolina has never seen anything like the new Children's and Women's
Hospitals. Neither have most other states. The new hospitals are the only ones in North
Carolina to offer complete inpatient and outpatient care for women and children in one
convenient location. Together, the facilities encompass more than 441.350 square feet, k

still, the physical facilities alone
— the patient rooms, operating suites
and recreation areas — do not make the
hospitals what they are.

"It's the staffs — the nurses and
therapists and everyone else who works
in these buildings — who are going
to make the real difference in the

care of patients and their families,"

I
Munson said. I

Nearly 1 ,700 employees —

including more than 400 nurses —

will work in the two hospitals. About

100 volunteers will help provide

comfort and support.

At the dedication celebration, UNC
employees, dignitaries and the public got their
first real look at the new hospitals. Following the
speeches, tours were offered to guests, along
with a variety of entertainment ranging from
storytelling and puppet shows to musical and
dance performances.

Among the dignitaries on hand were
Molly Broad, university system president; Robert

UNC President Molly Broad

N. Shelton, PhD, executive vice chancellor and
provost; U.S. Reps. David Price and Bob
Etheridge of North Carolina; members of the UNC
Health Care board of directors; and members of
the university tx)ard of governors. In addition, a
contingent of artists from California, who had
learned of the new hospitals from a friend of
George Sheldon, MD, former chair of the
Department of Surgery, traveled to Chapel Hill for
the event. The artists had created and donated a
significant number of paintings and sculptures for
the new buildings.

The evening of the dedication, aboiA 300
supporters turned out for a fundraising reception
hosted by The Medical Foundation of North
Carolina Inc. in the new Women's Hospital lobby.
Valerie Parisi, MD, MPH, Robert A. Ross Professor
and chair of the Department of Obstetrics and
Gynecology and Alan Stiles, MD, Brewer
Distinguished Professor and chair of the
Department of Pediatrics offered a heartfelt
champagne toast to the future of the facilities.

''^ « J 4

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I

m-: ,1

Children's » Hospital

Each year more than 32,000 children from all
100 N.C. counties come to UNC for over 92,000 visits
for diagnosis and treatment. The new hospital includes
a comprehensive Children's Outpatient Center and 136
inpatient beds. Key features and services of the new
Children's Hospital include:

• Large, all-private rooms with private baths and built-in
sleeping accommodations for parents

• Centralized children's clinics

• A Newborn Critical Care Center

• A Pediatric Intensive Care Unit

• A children's Intermediate Cardiac Care Unit

• The state's only accredited K-12 hospital school
to help children keep up with their classroom
studies during their hospital stay

• An indoor two-story, park-like recreation center
that includes a play area for toddlers and a lounge
and music room for teens

• A cafe next to the balcony that overlooks the
lobby

'This building allows us to provide the
children of North Carolina something they have not
had — a facility that brings together complete
inpatient and outpatient care for children in one
location, a true children's hospital," said Dr. Alan Stiles.

"^JJ

Women's ^^ Ho

The new Women's Hospital offers comprehensive
wellness and specialty services for women of all ages,
including primary care for women in the Triangle area
and specialized medical and surgical treatment for
women from across the state. The hospital's medical
staff provides expert care in the areas of maternal-fetal
medicine, gynecologic surgery, advanced laparoscopy,
urogynecology, reproductive endocrinology and cancer
The facility has 65 beds, including 14 labor and delivery
beds, plus the newborn nursery.

The Women's Hospital features:
• Large, all-private rooms with private bathrooms,
conversation areas and convertible sofas for a family

member to stay with the patient

• Women's primary care and specialty clinics
conveniently located

• Expert maternity care in a warm, restful environment

• A newborn nursery

• Full-time lactation consultants

• The Women's Resource Center, an interactive library
staffed by a health professional

• A solarium with a fountain and a skylight, offering a
pleasant environment for patients and their families

• Six shared operating rooms for women's and
children's surgery

• A chapel and a full-time hospital chaplain dedicated
to meeting the spiritual needs of women

The two hospitals will house expanded radiology
services for both children and adults, as well as a
pathology laboratory, pharmacy and outpatient
physical/occupational therapy services. The new
hospitals stand between the N.C. Neurosciences
Hospital and N.C. Memorial Hospital, which previously
housed all UNC inpatient care services.

"Now, the vision ... has been realized in order to
provide 21st century, state-of-the-art facilities in which
to care for women and their infants," said Dr Valerie
Parisi. "Note the emphasis we have now been able to
place on family-centered maternity care and women's
wellness and disease prevention education, as well as
a focus on patient convenience, choice and shared-
decision making and responsiveness to life stage,
lifestyle and family issues."

*' •

A'

f^f

Oft

^

.//

-v

I II

600 tons of
structural steel

Among the largest and most complex
state building projects ever undertaken,
North Carolina's new side-by-side
hospitals for women and children have
441 ,350 square feet of floor space on
nine levels. The buildings contain:

• 600 tons of structural steel

• 2,200 tons of reinforcing steel

• 23,500 cubic yards of concrete

• 2.4 miles of corridors

• 1 6 elevators

• 189 miles of telephone and data cable

• 2,500 phone and fax outlets

• 1 73 electrical panels

• 29 isolated power panels for intensive
care units

• 720 smoke detectors

• 5,675 sprinkler heads

Craniofacial director brings
iifeiong UNC ties to new position

By Rebekah Butler

The experiences Amelia Drake, MD '81 , has had at
UNC extend far beyond those she has had as a physician.
In fact, they extend beyond those she had while a medical
student in the late 1970s and early 1980s. Dr Drake's
experiences at UNC go back to her birth at N.C. Memohal
Hospital. Now Dr. Drake is being introduced to all-new
experiences at UNC, having recently been appointed direc-
tor of the UNC Craniofacial Center.

Dr Drake credits her lifelong association with UNC
to her parents, both of whom were on UNC's School of
Medicine faculty. Having met at Johns Hopkins, they arrived
in 1954 when the medical school expanded to a four-year
program. Her father, Newton D. Fischer, MD, was in the
Department of Surgery and served as the first chief of oto-
laryngology from 1952 to 1981. Her mother, Janet J.
Fischer, MD, was in the Department of Medicine's division
of infectious diseases.

An early memory Dr Drake recalls of UNC is play-
ing in her father's office as a child. "I remember examining
a human skull in my father's office while waiting for him to
finish rounds on a Saturday," she said.

After growing up in Chapel Hill with four siblings,
all of whom became involved in health care, Dr Drake
decided to attend Cornell University in Ithaca, N.Y. "I chose
Cornell to see another area in the country and to have a dif-
ferent cultural experience," she said.

Upon graduating from Cornell in 1977, Dr. Drake
returned to Chapel Hill to attend UNC's School
of Medicine. "My medical school experience
was very strong. It was also wonderful to have
my parents involved as faculty," Dr. Drake said.

It was during medical school that Dr
Drake decided to pursue the specialty of oto-
laryngology, a choice Influenced by her father
Dr. Drake graduated from the School of
Medicine in 1981 and then went to the
University of Michigan Medical Center in Ann
Arbor to complete her residency in otolaryngol-
ogy. After finishing her residency, she did a
pediatric otolaryngology fellowship at the
Children's Hospital Medical Center of Cincinnati
in Ohio.

Dr Drake was directed to the fellow-
ship program at the Children's Hospital by
Harold Pillsbury, MD, the second chair of oto-
laryngology following her father "He told me that

if I wanted to return to North Carolina, pediatric ENT was an
area of need within the state," she said. 'This was enor-
mously helpful in directing my course of study."

Dr Drake completed the fellowship in 1988 and
returned to UNC the same year as an assistant professor of
surgery. Since 1 989, she has held joint appointments as an
assistant professor, then as an associate professor and full
professor, in surgery and pediatrics. She was one of the
first physicians in the state with fellowship training in pedi-
atric otolaryngology.

Working with children brings Dr Drake tremen-
dous joy. 'The medical care of children offers much reward.
Many days I am impressed by the spirit of the patients and
their families while dealing with serious medical condi-
tions," she said.

Dr Pillsbury, who has been Dr Drake's mentor as
well as colleague, described her gift for working with chil-
dren: "Dr Drake is one of the kindest, gentlest physicians
you could ever meet. She is a combination of a mother and
a doctor, adding a personal touch to our care of children.
She makes children feel comfortable coming to the hospi-
tal and allows their parents to feel very positive about what
procedures are being done."

Gerald M. Sloan, MD, professor and chief of the
division of plastic surgery, also spoke of Dr Drake's knack
for working with children. "She's great with children. She
has such wonderful rapport with them. With pediatrics you
work with children from infancy to late adolescence and

"The medical care of children offers much reward. Many days I am

impressed by the spirit of the patients and their families while

dealing with serious medical conditions, " Dr Drake says.

Amelia F. Drake

Husband

Craig

Children:

Connor. 12. and Cliff. 10

Personal Interests: Rowing

she is very good at adapting her style to chil-
dren of different ages. She obviously loves
working wWh children, and it shows."

Though she works with children who
have a wide range of ear, nose and throat prob-
lems, her passion is working with children with
ainway problems. Many of the procedures she
does are to help in the removal of children's
tracheostomy tubes.

The children's lives are improved
dramatically by removing their tracheostomy
tut)es. This was an area where I felt I could
make a difference because these children have
their whole lives ahead of them," Dr Drake
explained.

In helping children with airway prob-
lems, she works closely with UNC's pediathc
pulmonary doctors and nurses, carefully
reviewing videotapes of challenging cases
before embarking on a plan. "It is the coopera-
tive approach to patient care that I see as one
of the strengths at UNC," she said

Chapman McQueen, MD, assistant
professor of otolaryngology/head and neck
surgery, said, "Amelia has added new dynam-
ics to pediatric ainway surgery since her arrival
here at UNC. We are now on the cutting edge of
pediatric ainway surgery in the world, thanks
mostly to her guidance and wisdom."

Beyond her work as a physician. Dr.
Drake is also the recently appointed director of
the Craniofacial Center, located in the School of

Dentistry. She took
over the position in
February after the
retirement of the for-
mer director Donald
Warren, DDS, PhD.

The Craniofacial
Center works with
patients who have
cleft lip, cleft palate
and other craniofa-
cial anomalies. It is
made up of an inter-
disciplinary team of
professionals, using
a team approach to care for patients and their
families. Before becoming director, Dr. Drake
was a member of the team for 1 2 years.

"I was excited to assume more of a
leadership role within the university. It fits in
nicely with my work in pediatric ENT, because
a lot of the patients who come to the center
have airway or ear problems. I am also fortu-
nate to be working with a team of compassion-
ate and excellently qualified caregivers," Dr
Drake said.

Dr Sloan said Dr. Drake "brings her
own expertise as a pediatric otolaryngologist
as well as her leadership and organizational
skills. She also brings ideas and potential inno-
vations."

Besides her recent appointment as
director of the Craniofacial Center, Dr Drake
was named the Newton D. Fischer distin-
guished professor in otolaryngology/head and
neck surgery in 1998. Dr. Drake was the first to
be honored with the professorship, which
b)ears her father's name.

She was also elected to the local
chapter of the Alpha Omega Alpha society, the
School of Medicine's honor society, as a facul-
ty memt)er. Since 1 997 she has served as the
group's faculty counselor

'The position brings me closer to the
medical school, which made everything possi-
ble for me," she said. M

^

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The Music Man

Rocky Mount physician
k)cuses on patients
and culture

By Bemadette Gillis

For Dan Crocker, MD 70,
finding a way to say thank you is as
simple as lending a hand to others.
Whether he's contributing to his
community in Rocky Mount, N.C., or
to his alma mater. Dr. Crocker is a
firm believer in giving back.

Dr. Crocker showed that he
ruly lives by this belief when he
recently made a contribution in the
amount $150,000 to the UNC School
of Medicine through the Medical
Alumni Endowment Campaign. Dr.
Crocker included the commitment in
his will to establish a Loyalty Fund
merit scholarship, which will benefit
students interested in studying medi-
cine. "It was a very simple matter of
adding a codicil to my will. I hope,
however, to fund this commitment
duhng my lifetime, but until then, the
codicil covers my desire to give back
to the medical school."

Donating such a gift to UNC
was important to Dr Crocker, who
himself was a merit scholar while in
medical school. It was the least he
could do, he said, considering that
the school played such a major role
in influencing his medical career
^During my evolution as a student, I
was a recipient of several funds and
awards. I'm grateful to those who
helped me in the past, to the School
of Medicine and to the university."

Dr. Crocker has also given
back to the university by participating
in the Medical Alumni Association for

Daniel Lind Crocker, MD 70

Education: Davidson College. Davidson, N.C. - BS 1966
UNC School of Medicine -MD 1970

Practice: Eastern North Carolina Medical Group, P.LLC. in Rocky Mount, N.C.

Wife: Brenda Sue Lynch Crocker

Cliildren: Natalie Ih/es in Raleigh. N.C. and Sue Ellen lives in Wilmington. N.C.

Personal Interests: Playing the trumpet, fishing, hunting, water sports and
back packing in the West

many years. He served as president of the association
from 1984 until 1985 and is currently a member of the
Endowment Committee.

Dr. Crocker's involvement v\/ith UNC first began
In 1966 when he received his undergraduate degree
from Davidson College and then entered the School of
Medicine shortly thereafter He said UNC was the first
school to which he was accepted, and making the
choice to attend wasn't difficult. "I was on the waiting list
for Bowman Gray, but I didn't want to wait, and I didn't
enjoy my interview at Duke," he joked.

What Dr Crocker did enjoy once he got to
UNC was his experience in the hematology/oncology
division. During the summers between school, he
worked in the hematology research labs, under the
direction of Dr. Richard I. Walker Dr. Crocker said his
love for hematology was inspired by Dr Walker and oth-
ers, including Drs. Harold Roberts, Jeff Palmer, John
Parker and John Herion. "I was always happy with
whatever I was studying at the time, but the people in
the department guided me, so ultimately, I chose hema-
tology."

He also had contact with doctors in other
departments as well. Dr Campbell McMillan In the pedi-
atric hematology/oncology division, Dr William BIythe in
nephrology and Dr James Bryan in internal medicine
encouraged him while he was studying to become a
doctor "All of those people were heroes to me," Dr
Crocker said

Once he graduated from the School of
Medicine in 1970, Dr Crocker interned and completed
his first year of medical residency at Parkland Memorial
Hospital in Dallas, Texas. He then returned to UNC for
his senior residency and later research and clinical

fellowship in hematology from 1973 until 1975.

Dr Crocker, who grew up on a farm in Selma,
N.C, wanted to return to eastern North Carolina once
his fellowship ended. It was important to him and his
wife, who also grew up in Selma, to remain close to both
of their families, so when he was offered a chance to
join to join Boice-Willis Clinic in Rocky Mount, he could-
n't say no.

Specializing in internal medicine, hematology
and oncology, he first joined the clinic in July 1975 and
remained there until he started his own clinic in May
2000. Dr Crocker said Dr John Chambliss, who was a
senior member of Boice-Willis Clinic at that time, had a
wonderful reputation among N.C. Memorial Hospital
house officers, fellows and faculty because of his out-
standing patient care, and that helped draw him to
Rocky Mount.

Also, the Boice-Willis Clinic philosophy was
consistent with what he had enjoyed at UNC. 'They
accepted patients all across the board regardless of
their financial background," Dr Crocker said.

Dr Crocker has been able to continue that
philosophy of treating all patients throughout his years
of practicing at the Boice-Willis Clinic and at his current
practice, Eastern North Carolina Medical Group.
While at the Boice-Willis Clinic, he served as the clinic's
president for eight years and was able to attract
many physicians to Rocky Mount, allowing the clinic to
better care for a wide range of patients, he said.

Continuing his belief that patients of all finan-
cial backgrounds should receive care, he was also able
to set up a satellite clinic serving a highly indigent pop-
ulation in nearby Enfield. "I'm proud to have been the
one who shouldered the starting of the clinic. At least

my evolution as a
stud^iLI was a recipient of
seve

I'm Uateful fo^lNbfi^ who
helped me in the pa^ to
the School of Medicine aiidnk
to ffiftiiiirrrTffi'"

this positively impacted one of many
small eastern North Carolina communi-
ties where there is a significant indigent
population."

Dr. Crocker's work in Rocky
Mount goes beyond his efforts at the two
clinics. He currently works with five nurs-
ing homes, including Nash Grove
Nursing Home, where he serves as med-
ical director. He said that as his patients
began to get older, it seemed natural for
him to continue caring for them when
they moved into nursing homes. "A lot of
our patients end up in nursing homes,
and I've tried to make my practice a con-
tinuum of service."

He adds that his obligations are
to all of his patients; it doesn't matter if
they live in nursing homes. "It's not finan-
cially rewarding, but the rewards come in
other ways. Treating these patients rep-
resents the continuum of care that all
patients need and deserve."

Through his work at the clinics
and nursing homes, Dr Crocker has
been able to have an impact on the
health care of the people of Rocky Mount
and surrounding communities. Dr.
Crocker said he is proud of his accom-
plishments as a physician and sees no
reason to practice anywhere else.
"Rocky Mount is a place where good
medicine has been practiced, and I have
had no reason to uproot myself from my
patients. It's also been easy for me to be
an active member of the community
here."

One contribution Dr Crocker
has made to his community has nothing
to do with medicine. A lifelong music
lover, he was instrumental in developing
the Tar River Orchestra and Chorus.

Dr Crocker said his mother,
who played the piano, encouraged her
children to pursue music. His brother is a
singer, and his sister is an accomplished
pianist. Dr Crocker first picked up the
trumpet in the fifth grade and has played
ever since. He played throughout college
but stopped during medical school.
However, after moving to Rocky Mount he
found opportunities to play with a wind
ensemble at N.C. Wesleyan College.

Then in 1986, he helped found
the Tar River Orchestra and Chorus and
has been the president of the board of
directors for the past 16 years. He has
been involved heavily with raising funds
and also as a participant in several musi-
cal ensembles. "I love music, I love play-
ing and I enjoy the people who partici-
pate along with me," Dr Crocker said.
"It's a nice diversion from health care."

Putting his personal satisfaction
aside. Dr. Crocker pointed out that the
Tar River Orchestra and Chorus has
allowed him to give something to the
entire community. "Before it began.
Rocky Mount only had one choral con-
cert a year, but now residents can enjoy
seven or eight."

Dr Crocker said his motivation
for establishing the Tar River Orchestra
and Chorus was to help expose the peo-
ple of eastern North Carolina to as many
cultural events as possible, which some-
times can be hard to find in that part of
the state. "Because eastern North
Carolina is less populated than other
parts of the state, centers of culture are
not as prevalent. This has been a major
cultural effort, which has been well
received." iTTl

I

J

cSEVENTS

Larry Ketth, assistant dean, director of recruitment, above left, Cheryl F. McCartney, MD, above right,
executive associate dean for medical education, and Georgette Dent, MD, associate dean for student
affairs, spoke to incoming medical school students during annual orientation, below right.

Kenneth M. Ludmerer, MD, professor of
both medicine and history at Washington
University in St Louis, left, speaks with
Stuart Bondurant, MD, UNC professor of
medicine and former dean of the School
of Medicine, prior to giving the 19th
Spicer-Breckenridge Memorial Lecture.
Dr. Ludmerer spoke on 'The Coming of the
Second Revolution in Medical Education."

Incorporating faith into
practice and precepting

By l^therine Savage

As physicians pay increasing attention to the role
of faith and spirituality in medical care, medical education
is beginning to reflect this dimension of practice. Research
findings indicating improved health outcomes, compared to
control groups, for patients with strong religious affiliations
or patients for whom prayers are offered have reinforced
this trend.

Participants in the School of Medicine's Faculty
Development Program in General Internal Medicine chose
to focus on physician and patient attitudes and preferences
regarding spirituality in the medical encounter for the col-
laborative research study they conducted at their seven
institutions. Termed the RESPECT study, it found that "a sig-
nificant percentage of patients perceive prayer (whether it
is done by their doctor, with their doctor, or for their doctor)
is linked to improvements in health" (J Gen Int Med
16[suppl 1]: 176). Although many of the 444 physicians in
the study believe that patients' spiritual practices affect
health outcomes, and "a smaller but significant number
believe that physician prayer will improve patient out-
comes," there is nevertheless a large gap in the prevalence
of these beliefs among physicians compared to patients
(JGIM: 190).

While approximately half of the physicians in the
survey favored further training in spirituality and medicine,
the RESPECT study found that "fonnal spirituality training
related to medical care" has been "sparse in medical
school and almost non-existent thereafter" (JGIM: 101).
However, change is underway as a number of U.S. medical
schools are adding courses to their curricula. Between
1 994 and 1 998, the number of schools teaching courses
on religion and spirituality issues grew from three to
approximately 50. Further evidence of the new emphasis on
this aspect of health and medicine ranges from Harvard
Medical School's series of conferences on Spirituality and
Healing in Medicine to the formation of the National Institute
for Healthcare Research, a nonprofit organization focusing
on the relationship between spirituality and health that has
awarded grants to 19 medical schools for curriculum devel-

opment in this area.

In North Carolina, part of the traditional Bible Belt,
it is not uncommon for physicians to discuss spiritual
issues with patients, particularly those who are facing
severe illness and who request physicians' prayers.
Medical students who are assigned to community-based
rotations in practices with a religious focus are exposed to
a perspective that may be different from what they
encounter elsewhere in their education.

Dr. Bruce Jackson, an obstetrician-gynecologist in
Boone, is in a solo practice that is explicitly religious. He
believes that through his vocation, he is doing God's will. Dr
Jackson found that arrogance created by medical school
made him think he could fix everything; he learned that he
could not. Now he wears a white coat with a lapel pin of a
crescent wrench, symbolizing his belief that he is one of
God's tools. He points out that the wrench is adjustable,
reflecting his response to each person's individuals needs.
"If people have to ask" what the wrench means, Dr. Jackson
says, "we're not doing it right."

He believes that his practice conveys a message
through its sen/ice-oriented approach, books that are avail-
able for his patients to read, and the fact that he will pray
with and for patients. Although he emphasizes that the doc-
tor should not ask the patient whether she desires prayers,
the nurses tell patients during pregnancy or pre-operative
workups, "If you want to pray, Dr. Jackson is comfortable
praying with you." Dr, Jackson feels that if patients know
that he is doing the best he can to do God's will, it relieves
him of a burden.

Over time, Dr Jackson's commitment to prayer
has evolved into a ritual in which the staff forms a prayer
circle and prays together at the beginning of each day Dr.
Jackson estimates that 60 to 70 percent of the medical stu-
dents he has precepted have been receptive to his religious
focus. Those who are uncomfortable do not participate in
the prayer circle. He acknowledges that a student's dis-
comfort with his approach could keep him and the student
from clicking as well. However, he feels that students who
are neutral toward his explicitly religious focus still find a lot

to respond to: his ener-
gy level, sense of humor,
and commitment to stay-
ing up-to-date in his
field.

Dr Jackson's
perception of students'
gain from their time with
him is borne out by stu-
dent evaluations, which
consistently rate him as
excellent. Rhonda

Vestal, who recently
completed her second
year of Introduction to Clinical Medicine rotations in Dr
Jackson's practice, felt as though "Dr Jackson has a very
strong bond with his patients due to their common strong
faith in God." She noted that Boone is a relatively small
town where people know each other well and where reli-
gion is a large part of people's lives. Therefore, "Dr
Jackson's incorporation of religious beliefs into his prac-
tice only strengthened the doctor-patient relationship."
Vestal's own feeling during her time in the practice was
one of admiration for the relationship that was fostered by
"Dr Jackson's willingness to pray with his patients and
reassure them that God was caring for all of them, includ-
ing Dr Jackson as he provided medical care for his
patients."

Dr Richard Berry, who practices internal medi-
cine in Whiteville, says, "I personally believe that there is a
greater power, whom I call God, [who] is the ultimate heal-
er guiding the physician and the patient in the healing
process." Although he does not consider his practice to
be an explicitly religious one, Dr Berry says that his
patients are aware of his beliefs. "I tell all my patients when
they compliment me for healing them that I did no healing,
that in essence their body did its own healing and that it is
through me that God works."

While he shares his own beliefs with the students
he precepts, Dr Berry says, "I do appreciate and honor the

rights of students as well as patients to believe what they
want to, and in no way will I force any religion or belief on
any person." The subject of religion in the practice of med-
icine is incorporated into his teaching from several angles.
As Dr Berry discusses with students how they would react
to or interact with patients with different beliefs, he some-
times shares his own experiences with his patients who
are Jehovah's Witnesses. Although he disagrees with
"their beliefs and interpretations of the Bible in regard to
blood and blood products, I will in no way force them to
take blood products. I have on one or two occasions been
the physician who had to pronounce Jehovah's Witness
patients dead because of their refusal to take blood prod-
ucts." Reviewing the ethical implications of such experi-
ences is an important exercise in teaching and learning.

Dr Berry also tries to make the medical and
nurse practitioner students he precepts aware of the
increase of examples in the literature pointing to signifi-
cant benefits to the healing process when a patient's spir-
itual aspect is addressed. "Just treating with medicine, and
not addressing the mental and spiritual aspects of a per-
son's disease, can sometimes not fully reach the etiology
of the problem," according to Dr Berry. He t)elieves that it
is always beneficial to treat the whole person - body,
mind, and spirit - and that addressing spiritual issues with
patients "is essential to complete holistic healing." till

New digital imaging system
revoiutionizes woric, patient
service tiirougiiout system

18

By Stephanie Crayton-Robinson "If the image doesn't look quite like you need it to

From the time the radiologic technologist hits the look, you can make it darker or lighter, bigger or smaller, or
send button, it may take hours before the patient hears, 'You rotate it or flip it, so that you can see everything you need to
can go home now, Mr. Jones." That's because the process of see about that image," Barba said. "It's not something that film
acquiring, storing, transmitting, printing, transporting and can do. Once it's printed it's pretty much a static picture."
interpreting images on film is a lengthy one. PACS runs through an intricate wire connection that

But thanks to UNC Health Care's new Picture allows information to travel quickly from place to place.
Archiving Communication System (PACS), the waiting time for Anyone with access to UNC Health Care's Intranet can view
physicians and patients has been cut. PACS. Location is not a barrier. "My physician sitting at

PACS is a high-tech, digital way for any department Highgate Family Medical Center can talk to a radiologist and
to view a patient's X-ray information. "Film is restrictive both of them can view the same image and they can discuss
because it can only be at one place at one time," said Jim my health," said Tom Boyd, Information Services Division pro-
Barba, educational PACS coordinator for the Department of grammer and analyst.

Radiology. "With PACS, because it's electronic, that same 'This is truly a uniquely integrated system," Barba

imaging information is located in a central place that every- said. "PACS blends into the user's current work location, he
one can go to and look at simultaneously." or she can conference on the PC, or he or she is able to

This new and improved way of communicating access images from home."
images uses special software designed to
display and maintain an archive database.

"We're now in the forefront of tech-
nology," said Alicia Corbett, PACS trainer
and applications programmer for the
Information Systems Division (ISD).

"It'll be a good tool for teaching." At
UNC, the system will operate through the
Web. Once logged on to a workstation, the
user can search for the images they need
by physician, patient name, medical record

number or date. Within minutes, PACS then ^H^^^S^ ^^^^^^^^^^^^^^^V A
indicates where the images are stored. From
there with the click of the mouse, the user

can pull up the desired image and adjust the ^^^^^B^V IV ^J^^B l^^K s

system to suit his or her needs. The PACS
system will allows for the images to be
manipulated.

Jim Barba, right, educationai PACS coordinator, stiows ttie wide-ranging
capabilities of PACS.

The digital Imaging system uses special software to communicate a patient's X-ray Information.

A faster, more diverse retrieval system
means it w/ill take less time to get much-needed
diagnostic or treatment infomnation - and less time a
patient has to wait.

The PACS project is a collaboration of ISD
and the radiology department, w/hich is the first area
to use PACS. Equipment was installed last
December, and radiology began training its staff to
use the new system the first quarter of 2001 . Training
for other departments is in full swing and should
conclude this year The Neurosurgery l_aboratory
and Ear, Nose and Throat (ENT) were pilot areas for
Web access to radiology images. This is truly an

enterprise-wide system," Boyd said.

"We're trying to organize everything so that
when cardiology comes on board, there are all the
right holes for them to jump right on board,"
Boyd said. "All the tools are the same. This is just
going to provide them with the means to store their
data."

"As we are training various groups, I think
they're beginning to realize that this new PACS sys-
tem is a real time-saver," Corbett said. 'The X-ray
system will not go away, but in the time that it takes
to prepare film, PACS has long since had that image
up and ready." HIl

John L. Watters, MD '50, and his wife, Beth, live close to
their five children, eight grandchildren and great-grandson,
John Piper Bissonnette. The couple enjoys retirement, with Jack
sometimes playing golf.

James Burrus, MD '57, serves on the American Medical
Association's Senior Physician Sen/Ices Board as medical
director for the Cleveland County Alliance for Health. He also
serves on the local hospital's foundation board. He says, "Life
Is good but busy since 'retirement.'"

Joel D. Conner, MD '57, retired from practicing gynecology
in April after 38 years of private practice in Gastonia, N.C.

Zell A. McGee, MD '61, is a professor of medicine at the
University of Utah in the division of Infectious diseases. In the
spring he was awarded the Leonard W. Jarcho, [VID,
Distinguished Teaching Award for the high values he exempli-
fies to both students and colleagues.

Dave M. Davis, MD '63, Is the director of Piedmont
Psychiatric Clinic in Atlanta. He was recently visited by neuro-
surgeon Ira Hardy, MD '63, at his summer house In
Cashiers, N.C.

William H. Katz, MD '74, and his wife, Joan, left Maine after
living there 23 years, and William has stopped practicing
obstetrics. The couple now lives In Easton, Md., where William
is practicing gynecology.

Margie Sved, MD '79, left Dorothea DIx Hospital In Raleigh,
N.C, after over 1 5 years of service. She is now working half time
In private psychiatry practice and half time with Wake Human
Sen/Ices. She has two children Sara, 15, and Eliana, 8, and also
serves as a foster mother

work focuses on helping state health departments develop their
Injury surveillance capacity.

Andrew Wallach, MD '91, a clinical assistant professor of
medicine at the New York University School of Medicine, has
recently been named associate director of the Internal
Medicine/Primary Care Clinics at Bellevue Hospital in New York,
N.Y. E-mail him at andrew.wallach@med.nyu.edu.

Edward Primka, MD '92, and Lynda Primka, MD '92,

recently moved to Knoxville, Tenn., where Edward has joined
Dennatology Associates of Knoxville. The couple has three
sons, Teddy, 8, Alex, 6, and Dan, 2.

Paige Walend, MD '93, and her husband, Larry Tamburro,
Md., celebrated the birth of their daughter, Olivia Anne, In June.
Olivia joins the couple's two-year-old daughter, Sarah. E-mail
Paige at palgelarry@mindsprlng.com.

Jacqueline Campbell-Sylvester, MD '94, lives In
Laurinburg, N.C. In Febaiary 2000 she opened a private prac-
tice, Babies Etc. OB/GYN, PA.

Paul H. Bowman, MD '95, is the chief resident of dermatol-
ogy at the Medical College of Georgia in Augusta. In 2000 he
received the Medical College of Georgia Excellence In Teaching
Award. In June he attended the annual meeting of the Scottish
Demriatological Society, which he received a scholarship to
attend from the American Academy of Dennatology.

Elena Herndon, MD '95, and Tony Hemdon, MD '95,

welcomed the birth of twins, Sammy and Katie, in October 2000.
Elena has completed psychiatry board certification. Tony is cur-
rently the chief resident of urology at the University of
Connecticut In Fanmlngton. Next year he will complete a pedi-
atric urology fellowship at Riley Children's Hospital at Indiana
University In Indianapolis.

Carolyn Church Davis, MD '96, and North J. Davis, MD
'96, celebrated the birth of Falrchlld Madeline in March.
Fairchild joins the couple's two-year-old son, Legend. In July,
North joined a private practice pathology group in Gainesville,
Ga.

W.L. Wells Edmundson, MD '80, began working with
Raleigh Medical Group in Febmary. His daughter, Erin, 19, plays
soccer at the University of Mississippi, and his son, Brian, 1 6, is
a sophomore at Broughton High School In Raleigh, N.C, where
he plays tennis.

Gerald T. Gowitt, MD '82, was recently named chief med-
ical examiner for DeKalb County, Ga., a suburb of Atlanta. He
lives with his wife, Vivian, and their two children, Thomas and
Gail. E-mail him at ggowltt@aol.com.

Liz Engelhardt, MD '85, works as an occupational medicine
physician at 3M in St. Paul, Minn. She and her husband, Jim,
have two children Michael, 7, and Kaitlyn, 4.

Kirsten Gross Girkins, MD '88, and her husband, Tom,
celebrated the birth of their first child, Benjamin Thomas, last
December. Kirsten works in emergency medicine in Charlotte,
N.C.

Robert Berkenblit, MD '90, Is associate medical director at
Montefiore Imaging Center in Bronx, NY. He and his wife, Kiera,
celebrated the birth of their third child, Jamie Alexa, in May.
Jamie joins the couple's two other children, Carly, 6, and Brett,
3. E-mail Robert at R.Berkenblit@worldnet.att.net.

Carrie Alspaugh, MD '91, and her husband, Andy, wel-
comed the birth of their daughter, Claire Linden in July. Claire
joins two sisters, Cate and Laney.

Megan Davies, MD '91 , is a medical epidemiologist with the
Centers for Disease Control and Prevention. She works with the
National Center for Injury Prevention and Control, which pro-
vides national leadership in preventing non-occupational
Injuries and controlling their severity and impact. Her current

Kathy L. Garland, MD '98, and Saitjib R Mohanty, MD
'99, were married in November 2000 in Chapel Hill, N.C. Kathy
is a pediatrician at Guilford Child Health in Greenslxiro, N.C,
and Sanjib is a resident In internal medicine at Wake Forest
University Baptist Medical Center.

Erica Wolff, MD '99, was married in June 2001 In Davidson,
N.C. She and her husband, Ron Verleleeren, live In Action,
Mass., where Erica will complete her family practice residency
this year.

Benjamin B. Taylor, MD '01, has started his Internship and
residency at the University of Alabama In Birmingham.

Paul K. Perkins, CMED '29, died in July- He lived In
Mocksville, N.C. His specialty was general surgery.

Jesse Caldwell, CMED '39, died In July. He lived In
Gastonia, N.C. His specialty was obstetrics and gynecology.

Max Novich, CMED '39, died In November 2000. He lived In
Farmingdale, N.J. His specialty was orthopaedic surgery.

George Gentry, MD '59, died In January. He lived in
Roxboro, N.C. His specialty was family medicine.

Edward L. Stewart, MD '59, died In April. He lived in
Cleanwater, Fla. His specialty was neurology.

Shahane Taylor, MD '59, died In May. He lived in
Greensboro, N.C. His specialty was ophthalmology.

Louis M. Perlmutt, MD '77, died In April. He lived In Chapel
Hill, N.C. His specialty was radiology.

nih: two unc researchers
among top 10 in funding areas

Two UNC researchers were among the top 1 0 principal
investigators in their respective federal funding areas In
2000, according to the National Institutes of Health.

Dr. Richard Boucher, Kenan
professor of medicine and
division head of pulmonary
and critical care medicine at
UNC, was seventh in the list
of top-funded basic research
principal Investigators. Notael
laureate Dr. Stanley Prusiner
at the University of California
at San Francisco headed the
list. Boucher received $5.1
million in NIH grant funding
for cystic fibrosis research in
2000.

Dr. J. Richard Udry, Kenan professor of sociology and
professor of maternal and
child health at the UNC
School of Public Health, was
second in the list of top-fund-
ed clinical, social science
principal investigators (inves-
tigator-initiated grants and
centers only). Dr Donald
Morton of the John Wayne
Cancer Institute headed the
list. Dr. Udry received $8.4
million in NIH grant funding
for an adolescent health sur-
vey in 2000.

In June, the journal Science published a complete list of
scientists in he upper echelons of federal funding.

Dr. Boucher, who also directs the university's Cystic
Fibrosis/Pulmonary Research and Treatment Center, has
published more than 300 articles on cystic fibrosis and
gene therapy. He helped develop a gene "knock-out"
mouse model for studying cystic fibrosis experimentally,
conducted both animal and human trials of gene therapy
for cystic fibrosis lung disease, and developed novel
drugs that are t)elng tested for the treatment of cystic
fibrosis lung disease. Cystic fibrosis, or CF, Is the most
common lethal genetic disease in the white population,
affecting one in 3,300 births.

Dr Udry's grant is part of the UNC-based National
Longitudinal Study of Adolescent Health (Add Health),
which made national news with the 1997 research find-
ings that strong and supportive ties between parents and
children help protect adolescents against a variety of
risky kjehaviors, including substance abuse, early sexual
activity, pregnancy, emotional distress, suicide and vio-
lence.

NIH funding for research at UNC jumped more than 20
percent in fiscal 2000, according to new figures released

in March by the federal agency. UNC faculty received
$207 million in NIH funding - up from $171.3 million in
1999 - ranking 13th overall among private and public
universities nationwide, and up from 14th last year

Fiscal 2000 overall research funding at UNC topped the
$375 million mark for contracts and grants awarded for
research, teaching and public service - an increase of 9
percent over the previous fiscal year.

UNC STUDY PINPOINTS GENE

CRUCIAL FOR FEMALE EMBRYO SURVIVAL

A gene discovered by UNC scientists appears to be cru-
cial for female embryo survival.

A study by UNC researchers and published In the August
issue of Nature Genetics journal furthers the under-
standing of a fundamental biological process in mam-
mals and conthbutes important new knowledge to gene
regulation in the developing embryo. It also has Implica-
tions for problems such as fetal loss, tumor development,
birth defects and mental retardation.

The report notes that the gene, called eed, when func-
tioning nonnally in female mouse embryos, keeps the
paternal X chromosome inactive and many of its genes
shut down In early placental cells. In the new research,
female embryos without a functioning eed do not survive
because of problems in fonning placentas.

Other studies have shown that the gene called Xist is
responsible for putting the molecular brakes on the X
chromosome only. Since female mammals have two X
chromosomes PCX) and males have txDth an X and a Y
(XY), an imbalance occurs t>ecause female embryos
have twice as many X-llnked genes.

That's where Xist comes into play. It gets switched on
early in the development of the female embryo. This gene
is activated from the X chromosome that's going to be
shut down, which in early placental material Is only the X
from the father, according to Dr Terry Magnuson, senior
author of the new study and Kenan professor of genetics
at the UNC School of Medicine.

"Once the paternal X chromosome is shut down, then the
cells must continue to divide and keep it shut down. Until
now, It's not been understood what maintains this X in an
Inactivated state. Now we know that eed plays a role in
this process," said Magnuson.

"Without eed functioning nonnally, the father's X chro-
mosome Is shut down and then it comes back on. When
that happens, too many X chromosome genes are active,
there are problems forming placental tissue, and female
embryos die."

The new findings also suggest that eed may be critical in
a fundamental process known as imprinting, a phenom-
enon in which a specific gene is expressed, or switched
on, depending on whether It Is Inherited from the mother
or the father

- Leslie H. Lang

WILLIAM ARENDSHORST, PHD, professor of cell and
molecular physiology, has been elected interim chair
of the department. He also recently served on the
Executive Advisory Board to organize an international
meeting on the Physiology and Pathophysiology of the
Renin-Angiotension System and Angiotensin II
Receptors. The meeting, sponsored by Astra-Zenica
Pharmaceuticals, was held in Prague,

CHRISTOPH BORCHERS, PHD, was appointed assis-
tant professor of biochemistry and biophysics and
faculty director of the UNC Proteomlcs Core. His
recruitment, including large investments in the pro-
teomlcs core facility, was made possible by the recent
UNC genomics initiative and a major, anonymous gift.

RICHARD BOUCHER, MD, professor of medicine and
chief of pulmonary medicine, has received The William
R. Kenan, Jr Professorship Fund for 2001-02 to sup-
port research and scholarly expenses.

The Kenan family and The William R. Kenan Jr.,
Charitable Trust created the William R. Kenan Jr.
Professorships and administers other Kenan-related
professorships to cement the bond between outstand-
ing faculty members and their students and to help
institutions retain, recruit and reward some of the
nation's top faculty.

JOHN BUSE, MD, PHD, associate professor of medi-
cine, chief of the division of general internal medicine
and director of the diabetes care center, was recently
elected to the national board of the American Diabetes
Association. He will serve a three-year term. Dr. Buse
is a former president of the Southeast Regional Board,
and has been active with the ADA for 20 years. He also
serves as chair of the association's Diabetes
Cardiovascular Disease Advisory Panel.

SHARON CAMPBELL, PHD, associate professor of
biochemistry and biophysics, was a recipient of a
2001-02 Hettleman Prize for Scholarly and Artistic
Achievement. Dr Campbell is using nuclear magnetic
resonance spectroscopy and other approaches to
gain mechanistic insights into regulation of signal
transduction by memb)ers of the Ras, Rac and Rho G
protein families.

CULLEY C. CARSON, III, MD, chief and professor of
urology, was awarded the 47th Annual Jesse H. Neal
National Business Journalism Award. He was recog-
nized for Best Editorial for The Changing Climate of
Urology. The Jesse H. Neal National Business

Journalism Awards were created by American
Business Media in 1955 to recognize and reward edi-
torial excellence in independent business publica-
tions.

KATE COPELAND, MD, clinical instructor and fellow
of urogynecology and reconstructive pelvic surgery,
and Georgine Lamvu-Schooler, MD, clinical instructor
and fellow of obstetrics and gynecology advanced
laparoscopic surgery, have been awarded 'Training in
Epidemiology and Clinical Trials" grants from the
National Institute of Child, Health and Human
Development.

PETER CURTIS, MD, director of the faculty develop-
ment program and professor of family medicine,
recently had an award named in his honor The award
recognizes people who have been key players in the
mission of the Department of Family Medicine — those
who recruit, retain and develop outstanding junior fac-
ulty so they can be of sen/ice to North Carolina and to
help link the statewide department together The award
is named for Dr Curtis in recognition of his lifelong
contributions to the Department of Family Medicine
across the state.

JEFFREY H. FAIR, MD, associate professor and chief
of abdominal transplant surgery, received a Carolina
Center for Public Service Grant to support Family
House of Chapel Hill. The project seeks to provide
affordable family accommodations close to UNC
Hospitals for transplant and oncology patients who
have traveled a considerable distance for evaluation
or treatment of serious or life-threatening illnesses.

WESLEY FOWLER, MD, vice Chair of the Department
of Obstetrics and Gynecology, has been appointed
chair of the Residency Review Committee for
Obstetrics and Gynecology effective Jan. 1 .

MICHAEL w. FRIED, MD, associate professor of
digestive diseases in the Department of Medicine,
received one of eight clinical center grants from the
NIDDK, National Institutes of Health. The study will
evaluate predictive factors and mechanisms of antivi-
ral resistance in African Americans with chronic hep-
atitis C who are treated with the latest combination of
pegylated interferon and ribavirin. Dr. Fried has been
appointed to the Executive Committee supervising this
study and is chairman of the protocol committee
responsible for developing the final cooperative
research protocol.

WILLIAM E. GARRETT JR., MD, chair of the Department
of Orthopaedics, has been selected president-elect of the
American Orthopaedic Society for Sports Medicine. He
will serve as president-elect until July, when he will
become vice president. He will tjecome president of the
organization in 2003.

ADAM GOLDSTEIN, MD, assistant professor of family
medicine, received an Office of the Provost Award at the
2001 UNC Public Service Awards Banquet. The Provost
Awards are given to recognize UNC faculty and staff who
have perfonmed extraordinary public service and/or
enabled such service by others. Dr. Goldstein was pre-
sented with a framed certificate and a check for $1 ,000.

JOYCE HARl^ MD, assistant professor of nutrition, has
been named the 2001-02 win-
ner of the Jefferson Pilot
Fellowship in Academic
Medicine. She will receive
$20,000 over a four-year peri-
od, in equal installments of
$5,000. She may use that
money at her discretion to sup-
port her scholarly endeavors.

CAROL LUCUS, PHD, chair and professor of biomedical
engineering, has received the department's Teaching
Excellence Award for 2001.

ANTHONY MEYER, MD, Roscoe B. G. Cowper

Distinguished Professor of

Surgery, has been named chair

of the Department of Surgery.

Meyer, who had been a vice

chair of the department since

1997, was named chair on Aug.

1. The previous chair, George

Sheldon, MD, stepped down

from the post he had served in

since 1984 to devote more time to teaching, patient care

and research at UNC.

Dr Meyer eanned his medical degree and his doctorate in
immunology and pathology from the University of
Chicago. He completed his surgical residency at the
University of California at San Francisco and served as
assistant professor of surgery and anesthesia at UCSF
before coming to UNC in 1984. Since then, Dr Meyer has
served as chief of general surgery, director of the surgery
residency program, co-director of the surgical critical
care residency program, medical director of critical care

for UNC Hospitals, assistant director of the N.C. Jaycee
Bunn Center, and director of bum research. He is a grad-
uate of the UNC Management Leadership Institute.

EDWARD PERL, MD, Sarah Graham Kenan professor of
cell and molecular physiology, received the Ralph W.
Gerard Prize for Outstanding Contributions to
Neuroscience by the Society for Neuroscience.

ETTA PISANO, MD, Chief and professor of breast imag-
ing, was awarded a $26.5 million
grant as principal investigator for
Digital Mammographic Imaging
Screening Trial (D-MIST). She
also has received a contract from
Sectra of Stockholm, Sweden,
for a project to design an FDA
trial for digital mammography
equipment and a contract from
Medical Optical Imaging in Charlotte for a project to eval-
uate diagnostic accuracy of infrared imaging for patients
going to breast biopsy.

HAROLD R. ROBERTS, MD, Sarah Graham Kenan pro-
fessor of medicine and pathology and founding director
of the Center for Thrombosis and Hemostasis, has been
selected by the American Society of Hematology to
receive the 2001 Henry M. Stratton Medal. The award,
which consists of an honorarium and a plaque to be pre-
sented Dec. 1 1 at the society's annual meeting in Orlando,
Fla., honors Roberts for his internationally recognized
contributions to hematology. Dr Roberts was the first U.S.
physician to treat hemophilia patients with factor Vila, a
medication that has been extremely successful in treating
hemophilia patients not responding to older or other
products.

OLIVER SMTTHIES, DPHIL, Excellence Professor of
pathology and laboratory medicine, was awarded the
Okamoto International Gold Medal Award.

BEAT STEINER, MD, clinical assistant professor of fami-
ly medicine, was selected to receive the 2001 David S.
Citron Award by the Executive Council of the Department
of Family Medicine. This award, which was established in
1982, recognizes a junior faculty memtjer who exempli-
fies the dedicated service and commitment to family med-
icine education, scholarship and health care delivery that
has typified Dr Citron's medical career This award
includes the opportunity to deliver the Citron Lecture at
the Annual Statewide Department of Family Medicine
Retreat.

2001-02 Loyalty Fund Scholars

The Loyalty Fund initiated the Merit
Award program In 1966 with a mod-
est stipend to six students. In the late
1980's the Medical Alumni
Association developed a strategic
vision to promote broader and higher
levels of alumni support, increasing
private gifts enabled the number of
scholarships to grow from 20 in 1 993
to 51 currently, each covering full in-
state tuition. The awards for 2001-02
are $5,000 for first-year students,
and $3,800 for second-, third- and

fourth-year students. Allied Health
Sciences are $1 ,500 each.

Merit Awards — An estimated 10
awards are made for highest honors
during MS I, II and III. (MS Ills to be
determined.)

Four-Year Scholarships —

Twenty-four students are supported.
Six awards to MS Is for four years
based on academics, leadership and
financial need. Two are designated
for MD/PhD students.

Fourth-Year — Generalist
Scholarships - Five awards to MS IVs
who have committed to a generalist
residency program.

First-, Second- and Third-Year
Scholarships — Three one-year
awards for each class based on
academics, leadership and financial
need.

Allied Health Sciences — Three
awards for students to be selected
by the Department Chair.

Carol Albright

Michael Alllngham

Jessica Bailey

Erin Bialas

Kirsten Brown

William Christopher

MSIII

MSI

MSIV

MSII

MSI

Buck

MD/PhD

One-Year

Four-Year

Merit

Four-Year

MSII
One-Year

Jennifer Bushman

Martin Butler

Tara Byer

Lisa Cohen

Heather Crouse

Donna Culton

MSII

MSIII

MSIII

MSII

MSIV

MSIII

MD/PhD

Merit

One-Year

Four-Year

One-Year

MD/PhD

Michelle Curtis

CariosEbert

Stephanie Falk

Matthew Foster

MSI

MSIV

MSIII

MSIV

One-Year

Four- Year

Four-Year

Four-Year

Summeriin Scholar

Richard Galinski Leila Ghassemian

Allied Sciences Allied Sciences

Norman Gray Stacy Haponik Gavin Henderson

MSI MSII MSIII

Four-Year Four-Year MD/PhD
Roberts Scholar

Michele Hernandez Noah Hoffman Naomi Huber

MSIV MSIII Allied Scier^ces

Four-Year MD/PhD

Holly Humphrey Ramon Jacobs

Juliet Klasing

Peter Kranz

ChadMcCall

Dalton McLean

MSI MSIV

MSI

MSIII

MSII

MSIII

Four- Year One-Year

MD/PhD

Four-Year

Merit

Merit

Rosengarten Scholar

David McSwain

MSIV
One-Year

Gordon Reeves

MSII
One-Year

Michael Rosenthal

Jonathan Routh

Rebecca Saids Stone

Carlie Sigel

Rishi Syal

Rebecca Walker

MSIII

MSIV

MSIV

MSIII

MSIII

MSII

MD/PhD

Four-Year

One-Year

Four- Year

Four- Year

Four-Year

Sheneika Walker

Allyson Whyte

Sara Wood

William Wood

MSIII

MSI

MSII

MSIII

One- Year

Four- Year
Cox Scholar

Four- Year

One- Year

Loyalty Fund Campaign 2000-01

Thank you to all of the volunteers
who served on campaign steering
committees in 2000-01 (Julyl-
June30):

Area Campaigns
Atlanta

Charles J. Fulp, Jr., M.D. '82

Co-Chair

Howard A. McMahan, M.D. 75

Co-Chair

Buncombe County

Stacey N. Ibrahim, M.D. '90

Co-Chair

Brentley D. Jeffries, M.D. '85

Co-Chair

Durham/Orange Counties

W. Woodrow Bums, Jr., M.D. '69

Co-Chair

Charles 0. Harris, M.D. '79

Co-Chair

Forsyth County

Richard C. Worf, M.D. '78 Chair

GuiHord County

H. Wallace Baird, M.D. '69

Co-Chair

Otis N. Fisher, Jr., M.D. '59

Co-Chair

MecMenburg County

Joseph L Albright, Jr., M.D. '82

Co-Chair

Bradley K. Weisner, M.D. '85

Co-Chair

New Hanover County

James R. Harper, Jr., M.D. '84

Co-Chair

John M. Herion, M.D. '83 Co-Chair

Edward W. Whitesides, M.D. '88

Co-Chair

Waice County

Sharori M. Foster, M.D. '79 Co-Chair
H. Clifton Patterson, M.D. '74
Co-Chair

Reunion Campaigns
Class of 1946

Crowell T. Daniel, Jr., M.D. Co-Chair

Robert S. Lackey, M.D. Co-Chair

Ira A. Abrahamson, Jr, M.D.

G. Denman Hammond, M.D.

Samuel H. Hay, M.D.

George A. McLemore, Jr, M.D.

Paul V. Nolan, M.D.

William E. Sheely. M.D.

H. Frank Starr, Jr, M.D.

Allen D. Tate, Jr, M.D.

John E. Weyher, Jr, M.D.

Thomas E. Whitaker II, M.D.

Class of 1951

William B. BIythe II, M.D. Co-Chair
John C. Herion, M.D. Co-Chair
Luther L. Anthony, Jr, M.D.
8. Bmce Berkeley, Jr, M.D.
R. Jackson Blackley, M.D.
Richard W. Borden, M.D.
Baxter H. Byerly, M.D.
A. James Coppridge, M.D.
Luther W Oehlbeck, Jr., M.D.
Corbett L, Quinn, M.D.
Edward Y. 0. Thorne, M.D.
JackW.Wilkerson, M.D.

26

Class of 1956

Richard A. Boyd, M.D.

Co-Chair

William E. Easterling, Jr., M.D.

Co-Chair

Lee A. Clark, Jr., M.D.

John W. Deyton, Jr, M.D.

Alexander F. Goley, M.D.

H. Neill Lee, Jr, M.D.

William W. McLendon, M.D.

John W. Ormand, Jr, M.D.

James F Richards, Jr, M.D.

W. R. Stafford, Jr, M.D.

Garland E. Wampler, M.D.

William B. Wood, M.D.

Class of 1961

Louie L Patseavouras, M.D.

Co-Chair

Joshua Tayloe, M.D. Co-Chair

Charles O. Boyette, Sr, M.D.

R. Carl Britt, M.D.

Daniel E. Clark, M.D.

John C. Council, Jr, M.D.

John W. Garden, M.D.

John C. Graham, Jr, M.D.

L. Morgan Hale, M.D.

Lloyd D. Lohr, M.D.

W. Stacy Miller, M.D.

A. Ray Newsome, M.D.

W. Ray Samuels, M.D.

W. Ferrell Shuford, Jr, M.D.

Zebulon Weaver III, M.D.

William H. White, Jr, M.D.

Class of 1966

Philip C. Deaton, M.D. Co-Chair
J. Lewis Sigmon, Jr, M.D. Co-Chair
J. Curtis Abell, M.D.
Robert R Barringer, M.D.
Timothy E. Cloninger, M.D.
George W. Cox, M.D.
William M. Caitchfield, M.D.
Edgar C. Garrabrant II, M.D.
Robert C. Gibson III, M.D.
N. Neil Howell, M.D.
Robert E. Sevier, M.D.
Robert G. Simmons, M.D.
W. Beverly Tucker III, M.D.

Class of 1971

Robert A. Bashford, M.D. Co-Chair

James S. Fulghum III, M.D. Co-Chair

Mary Susan Fulghum, M.D.

Co-Chair

James S. Coxe III, M.D.

Bertram C. Finch III, M.D.

Joe E. Gaddy Jr, M.D.

William D. Kassens, Jr, M.D.

Jonathan O McLean, M.D.

J. Allison Shivers, M.D.

John P. Surratt, M.D.

Class of 1976

Douglas C. Privette, M.D. Co-
Chair

R. Henry Temple, Jr, M.D. Co-
Chair

F Ray Thigpen, M.D Co-Chair
Sabra A. Woodard, M.D. Co-
Chair

W. Bryson Bateman, Jr, M.D.
Marjorie B. Carr, M.D.
Catherine J. Everett, M.D.
Joseph R. Haskett, Jr, M.D.
Charles V. Pope, M.D.
Thomas L. Speros, M.D.

Class of 1981

G. Williams Adams, M.D. Co-
Chair

Kenneth ft Blau, M.D. Co-Chair

Graham W. Bullard, M.D. Co-Chair

Frederick M. Dula, Jr., M.D.

Co-Chair

William M. Hemdon, Jr., M.D.

Co-Chair

G. Tillman Bailey III, M.D.

Michael C. Bumette, M.D.

David M. Cowherd, M.D.

David A. Crews, M.D.

Steven H. Dennis, M.D.

Amelia F Drake, M.D.

Willie S. Edwards, Jr, M.D.

David A. Goff, M.D.

M. Bradford Huggins, M.D.

Thomas S. Kaluzynski, M.D.

Stephen I. Moore III, M.D.

Paul M. Parker M.D.

Nancy M. Reierson, M.D.

Anne Marie A. Riether, M.D.

John W. Sanders III, M.D.

James D. Whinna, M.D.

Phillip M. Williford, M.D

William Winkenwerder, Jr, M.D.

Richard B. Yow, M.D.

Class of 1986

Mary Beth A. Carter, M.D. Co-Chair

Michael D. Carter, M.D. Co-Chair

Lisa F Dejarnette, M.D. Co-Chair

Lynne C. Garrison, M.D. Co-Chair

M. Todd Brown, M.D.

Charles B. Cairns, M.D.

Elizabeth T Clark, M.D.

Connie D. Harrill, M.D.

J. Curtis Jacobs, M.D.

Rebecca S. Kennedy, M.D.

Leslie C. McKinney, M.D.

Eric W. Miller, M.D.

Michael E. Norins, M.D., M.RH.

Francine A. Olds, M.D.

Steven R. Olson, M.D.

Class of 1991

Katrina H Avery, M.D. Co-Chair

Michael J. Lucas, M.D. Co-Chair

Gilbert ft. Upchurch, Jr., M.D.

Co-Chair

Frederick M. Weeks, M.D. Co-Chair

James T Al-Hussaini, M.D.

Carrie D. Alspaugh, M.D.

Mack N. Bames III, M.D.

L. Van T Crisco, M.D.

C. Neill Epperson, M.D.

Lisa M. Figueroa, M.D.

Tiffany S. Flanagan, M.D.

Catherine M. Gordon, M.D.
Parlyn T Hatch, M.D.
Leon W. Hemdon, Jr, M.D.
Drew A. Jones, M.D.
Sharon T. Kapeluk, M.D.
Helene R Keyzer-Pollard, M.D.
Chapman T. McQueen, M.D.
Richard J. Pollard, M.D.
Danny Silver, M.D.
Brian D. Smith, M.D.
Benjamin D. Sutker, M.D.
Sherri A. Zimmerman, M.D.

Class of 2001

Robert N. Marshall III, M.D. Co-Chair

Priya V. Rajan, M.D. Co-Chair

Elizabeth I. Abemathy, M.D.

Felicity A. Adams, M.D.

Anuja K. Antony, M.D.

Wendy M. Baer, M.D.

Craig G. Bates, M.D.

Adar T Berghoff, M.D.

Millicent C. Booker, M.D.

Josie B. Bowen, M.D.

Jennifer D. Boy, M.D.

Justin M. Burns, M.D.

Daniel R. Carrizosa, M.D.

Michael J. Casey, M.D.

Rotjert B. Christian

Sean V. Costabile, M.D.

Lynn B. Eckert

William L Fangman, M.D.

Elizabeth J. Geller, M.D.

Keisha L Gibson, M.D.

Cynthia R. Greenlee, M.D.

Justin B. Hauser, M.D.

Vicki C. Ho, M.D.

Shelley A. Houston, M.D.

Thomas L. P Javelona, M.D.

Benny L. Joyner Jr

Rohini Kanniganti, M.D.

Adair K. Look, M.D.

Hiroki Mitsuyama, M.D.

Priya V. Rajan, M.D.

Christin N. Richardson, M.D.

Aimee L Schimizzi, M.D.

Sherry V. Sedberry, M.D.

Samir V. Sejpal

Lorraine M. Stone

Carmen I. Teague, M.D.

Tony P Tsai, M.D.

Ramsey K. Umar, M.D.

Nam D. Vo, M.D.

Jennifer E. Yates

Adam Zanatlon

Loyalty Fund Budget FY 2001-02
$715,000

Student Scholarships and Programs
$258,100

Communications
$138,600

Operations*
$124,300

Health Sciences

Libraxy and

Technology Support

$40,000

Alumni Outreach
$126300

Medical Alumni

Endowment Fund

$27^00

xn of Budget dcacaae the percmtBgc

Report to Donors

Dear Medical School Alumni:

It is with great appreciation that I
announce to you the annual Report to
Donors for fiscal year 2CXXD-01 (July^une).
I am pleased to tell you that it was another
record-setting year for alumni support at
UNC School of Medicine.

Over 43 percent of medical
alumni contributed a total of $ 3.3 million
to benefit programs and services at the
School of Medicine. Of this amount, $ 2.6
million was restricted to support, for exam-
ple, much-needed professorships, fellow-
ships and lectureships.

The remaining $706,000 was
contributed by 38 percent of alumni to the
Loyalty Fund, the unrestricted fund that
provides support for important student,
faculty and alumni programs. These num-
bers are important as corporations and
foundations often look at the level of alum-
ni participation when deciding whether to
support the School. It would take an
endowment of $14 million to generate an
annual income of $700,000.

The Report that follows includes
the names of all alumni who made contri-
butions to any Medical Foundation
account between July 1, 2000 and June
30, 2001. Names in bold type recognize
alumni who contributed at the $1,000 level
or above. Names in italics recognize alum-
ni who gave $10,000 or more. Please call
me at The Medical Foundation at (800)
962-2543 if you have a correction to this
list. Every effort for accuracy has been
made.

Continued alumni participation
plays a critical role in helping to detenmine
the quality of programs available at your
alma mater Thank you again for your gen-
erous support.

Sincerely,

Jane M. McNeer,

Assistant Dean and Vice President

The Medical Foundation of North

Carolina, Inc.

PS. As you may know, UNC is in
an ambitious, University-wide $1.5 billion-
plus comprehensive capital campaign —
The Carolina First Campaign — which
began July 1999 and ends June 2006. All
gifts and pledges to the Medical School,
including the Loyalty Fund and Medical
Alumni Endowment Campaign, count
toward this important tundraising effort.

Honor Roll of Alumni Donors

2000-01
$1,000-$9,999 donors are printed in bold.
$10,000 or more are printed in bold italics.

CU\SSOF1929
Number in Class: 2
Percent Donors: 50%

Vance T Alexander, M.D,, Davidson, NC

CLASS OF 1931
Number in Ciass: 5
Percent Donors: 20%
J. Aiien Whitaicer, IM.D., Rocicy Mount, NC

CLASS OF 1933
Number in Ciass: 1
Percent Donors: 100%

Arttiur F Toole, M.D., Talladega, AL

CLASS OF 1934
Number in Ciass: 3
Percent Donors: 33%

William B. Patterson, M.D., Wailuku, HI

CLASS OF 1935
Number in Ciess: 4
Percent Donors: 25%

Jullen H. Meyer M.D., Roanoke, VA

CLASS OF 1936
Number in Ciass: 7
Percent Donors: 14%
Annie L WUkerson, M.O^ Raleigh, NC

CLASS OF 1937
Number in Ciass: 5
Percent Donors: 20%
W. SIceiile Hunt, Jr., M.D., Wiimington, NC

CLASS OF 1938
Number in Class: 7
Percent Donors: 14%

Horace H. Hodges, M.D., Matthews, NC

CU\SSOF1939
Numl>er In Class: 7
Percent Donors: 29%
Jesse B. Caldwell, Jr.. M.D., Gastonia, NC
Henry T. Clark, Jr., M.D., Cliapei Hill, NC

CLASS OF 1940
Number In Class: 20
Percent Donors: 35%

Inez W. EIrod, M,D,, Chartotte, NC
John B. Graham, M.D., Chapel Hill. NC
H. L«e Large, Jr, M.D., Charlotte, NC

French H McCain. M.D., Bkxxnfleld Hills, Ml
Hugh H McFadyen, M.D., Tucson, AZ
John L Ranson, Jr. M.D., Charlotte, NC
John H, Woltz. M.D., Charlotte, NC

CLASS OF 1941
Number In Class: 11
Percent Donors: 36%

Marcus I, Aderholt M.D., Thomasville, NC
Robert M. Hall, M.D., Raleigh, NC
Jack Hughes, M.D., Durtiam, NC
Claude Lowry Pressly, M.D., Charbtte, NC

CLASS OF 1942
Number in Class: 21
Percent Donors: 43%

Jeny H, Allen, M.D., Springfield, MO
Frederick A. Btount, M.D., Winston-Salem, NC
John F Lynch, Jr., M.D., Wrightsville Beach, NC
William E. Hoy, M.D., Ashland. KY
John H. Miller, M.D., Bartow, FL
James D. Piver, M.D., Emerald Isle, NC
George W. Plonk, M.D., Kings Mountain. NC
William Tenenblatt, M.D., Lake Worth, FL
R. B. Williams, Jr, M.D., Wilmington, NC

CLASS OF 1943
Number in Class: 42
Percent Donors: 21%

James R. Collett, M.D., Morganton, NC
John C. Foushee, M.D., Sanford, NC
William N. Hubbard, Jr, M,D., Kalamazoo, Ml
William F Hutson, M.D., Northbrook IL
Alexander C. Mitchell, M.D., Onchiota, NY
Sarah T Monow. M.D., Ph.D., Raleigh, NC
S. Matone Partiam, M.D.. Henderson, NC
Franic R. Reynolds, M.D., Wilmington, NC
Kenneth W. WilMns, M.D., Goldsboro, NC

CLASS OF 1944
Number in Class: 21
Percent Donors: 67%

RolDert J. Andrews, M.D., Wilmington, NC

J. Vincent Arey M.D., Concord, NC

Joseph W. Baggett, M.D., Fayetteville, NC

Hilda H. Bailey M.D., Salisbury, NC

Eart E. Correll, M.D., Kannapolis, NC

Brice T Dickson, Jr, M,D., Gastonia, NC

Ethel G. Lawner, M.D„ Jersey City. NJ

Isaac V. Manly, M.D., Raleigh, NC

Clarence M. Miller, Jr., MJ)., Sewiddey, PA

George D. Penick M,D,. Wilmington, NC

Charles A. Speas Phillips, M.D., Southern

Pines, NC

Robert R, Rascoe, Jr, M.D.. Wynnewood. PA

J. Mitchell Sorrow, Jr., M.D., Chapel Hill, NC

Charies W. Tillett, M.D.. Charlotte, NC

CLASS OF 1945
Number In Class: 24
Percent Donors: 54%

G. Walker Blair, Jr., M.D,, Buriington, NC

G. Robert Clutls, M.D., Greensboro, NC

A. Robert Cordell, M.D., Winston-Salem, NC

J. Hicks Corey, Jr, M.D., Chattanooga, TN
Courtney D, Egerton, Jr, M.D,, Asheville, NC
Grafton C. Fanney Jr, M.D , Bonita Springs, FL
Harold L Godwin, M.D., Fayettaville, NC

Kirtjy T Hart, Jr, M.D,, Petersburg, VA
Weldon H, Jordan, M,D,. Fayetteville, NC
David Josephs, M,D., Baltimore, MD
John H, Monroe, MD., Winston-Salem, NC
Roger A, Smith III, M,D,, San Bernardino, CA
Clifton F West, Jr, M.D., Chestertown, MD

CLASS OF 1946
Number in Class: 27
Percent Donors: 78%
Ira A. Abrahamson, Jr., M.D., Cincinnati,
OH

Julius Amer, M.D., Denver, CO
Walter C. Barnes. Jr, M.D., Texartena, TX
David Y. Cooper ill, M.D., Bryn Mawr, PA
Crowell T. Daniel, Jr., M.D., Fayetteville, NC
William W. Forrest M.D., Greensboro, NC
Mary Alice V. Fox, M.D., Mount Desert ME
William H. Grey, M.D., Staunton, VA
G. Denman Hammond, M.D., Arcadia, CA
Samuel H. Hay M.D.. Toccoa, GA
Robert S. Lackey, M.D., Charlotte, NC
Roland D. Matthews, M.D., Burlington, NC
James E. McKinney, M.D., Chattanooga,TN
Paul V. Nolan, M.D., Signal Mountain, TN
William E. Sheely, M.D, Alexandria, VA
H. Frank Starr, Jr., M.D., Greensboro, NC
David G. Stroup, M.D., Savannah, GA
Arthur R. Summerlin, Jr, M.D^ Raleigh,
NC

Allen D. Tate, Jr, M.D., Burlington, NC
John E. Weyher, Jr, M.D., Wilmington, NC
Thomas E. Whitaker 11, M.D., Greenville, SC

CLASS OF 1947
Number in Class: 14
Percent Donors: 21%

Thomas R. Newitt M.D., Escondldo, CA
Harry G. Walker, M.D., Statesville, NC
Sarah L Warren, M.D., Chapel Hill, NC

CLASS OF 1948
Number in Class: 22
Percent Donors: 27%

James A. Ew/art M.D., Walnut Creek, CA
Tyndall R Hams, M.D., Chapel Hill, NC
Louis T Kermon, M.D., Raleigh, NC
Julius A. MacKie, Jr, M.D, Bryn Mawr, PA
Shirley L Rivers, M.D., Tucson, AZ
Daniel T Young, M.D., Chapel Hill, NC

CLASS OF 1949
Number in Class: 35
Percent Donors: 31%

J. Dewey Dorsett, Jr, M.D.. Charlotte, NC
Christopher C. Fondham III. M.D.. Chapel Hill, NC
F Sidney Garciner, Jr, M.D., Fayetteville, NC
Frank H. Hamilton, Jr, M.D., Charlotte, NC
Odell C. Kimbrell, Jr., M.D., Raleigh, NC
Edward B. McKenzie, M.D.. Statesville, NC
Edwin W. Monroe, M.D., Greenville, NC
Rose Pully, M.D., Kinston. NC
Jack D. Summerlin, M.D., Indianapolis, IN
G. Earl Trevathan, Jr, M.D., Greenville. NC
Maxine D. Wallace, M.D., Oakland, CA

CLASS OF 1950
Number in Class: 35
Percent Donors: 69%
Gertrude A. Bales, M.D., Rochester, NY
Frederick O. Bowman, Jr., M.D., Chapel
Hill, NC

W. Grimes Byeriy, Jr, M.D., Hickory, NC
Jack 0. Carson, M.D., Grifton, NC

Elwood B. Coley, M.D., Lumberton, NC

John T. Dees, M.D., BaM Head Island, NC

Amzi J. Ellington, Jr, M.D., Buriington, NC

Mary B. Golby M.D.. Durham. NC

Buel K. Grow, Jr, M.D., Belle Meade, NJ

Joel B. Huneycutt M.D., Lake Wylie, SC

George Johnson, Jr., M.D., Chapel Hill, NC

William S. Joyner, M.D., Durtiam, NC

John A. KirWand, M.D.. Wilson, NC

Dan A. Martin, M.D., Madisonville, KY

John L McCain, M.D., Wilson, NC

Glenn D. Moak, M.D., Indianapolis, IN

James H. Peedin. Jr. M.D.. Burgaw, NC

J. Olin Perritt, Jr., M.D., Wilmington, NC

John W. Sawyer, M.D., Wilmington, NC

Eugene B. Sharpe, M.D., Asheville, NC

Lewis S. Thorp. Jr, M.D., Rocky Mount NC

Charles R. Vernon, M.D., Wrightsville, NC

John L Watters, M.D., Raleigh, NC

John R. Wilkinson. Jr. M.D., Hickory, NC

CLASS OF 1951
Numtier in Class: 35
Percent Donors: 63%

Luther L. Anthony Jr, M.D., Gastonia, NC
John S. Bark>w, M.D., Concord, MA

OIha A. Bamhill, M.D., Elizabethtown, NC
Daniel F Beals, M.D., Knoxville. TN
S. Bruce Berl^eley. Jr. M.D.. Goldsboro. NC
R. Jackson Blackley, M.D.. Raleigh. NC
William B. BIythe, M.D., Chapel Hill, NC
Richard W. Borden, M.D., Beaufort NC
D. Ernest Bulluck, Jr, M.D., Moorestown, NJ
Baxter H. Byeriy. M.D.. Tallahassee, FL
A. James Coppridge, M.D., Durtiam, NC
William A. Futch, M.D., Conyers. GA
R. Wharton Gaul. M.D.. Mun-ells Inlet SC
Matt C. Harper Jr. M.D., Kinston, NC
Hal B. Hawkins. M.D., Wilkesboro. NC
John C. Herion, M.D.. Chapel Hill, NC
Harold C. Lane, M.D., Rutherfonjton. NC
Kari L. Lawing. M.D.. Lincolnton, NC
Luther W. Oehlbeck, Jr, M.D., Ubelle, FL
Charies C. Stamey M.D., Winston-Salem, NC
Edward Y C. Thome, M.D., Wilson, NC
Jack W. Wilkerson, M.D., Greenville, NC

CLASS OF 1952
Number in Class: 6
Percent Donors: 1 7%

Charles H. Powell, M.D.. OrrtKind Beach, FL

CLASS OF 1954
Number in Class: 31
Percent Donors: 52%

Leiand S. Averett, Jr, M.D., High Point NC

Paul H. Brigman, M.D., Trinity, NC

A. Joseph Diab. M.D. Raleigh, NC

Malcolm Reishman, M.D.. Fayetteville. NC

Charles B. Fulghum, Jr, M.D., Atlanta, GA

J. Franklin Graves, M.D.. Edisto Island. SC

Sara L Hoyt, M.D., Rome, GA

James C. Parke, Jr., M.D., Charkme, NC

Cornelius T. Partrick, M.D., Washington, NC

Ely J. Peny, Jr, M.D., Kinston, NC

Allen Spencer, M.D.. Salisbury. NC

Nat H. Swann. Jr. M.D.. Signal Mountain. TN

William H. Weinel, Jr., M.D., Wilmington, NC

Edward S. Williams. Jr. M.D., Durham, NC
Stephen G. Wilson, Jr., M.D., Knoxville, IN

Virgil A. Wilson, M.D., Winston-Salem, NC

CLASS OF 1955
Number in Class: 49
Percent Donors: 59%
Julian S. Albergotti, Jr., M.D., Chariotte, NC
Ralph E. Brooks, Jr., M.D., High Point, NC
Griggs C. Dkskson, M.D., Charh>tte, NC
Charles F Eddinger, M.D., Spencer, NC
John W. Foust, M.D^ Chariotte, NC
J. Eugene Glenn, M.D., Jacksonville, FL
Robert L. Golby M.D., Durtiam, NC
James W. Hayes III, M.D., Burlington, NC
Charles L. Herring, M.D., Kinston, NC
William D. Huffines, M.D., Chapel Hill, NC
Samuel G. Jenkins, Jr, M.D^ Elizalxth
City,NC

Robert C. Jordan, Jr, M.D., Sanford, NC
Samuel B. Joyner M.D., Greenstxjro, NC
A. Smith Lineberger, Jr., M.D., Wilmington,
NC

William L. London IV, M.D., Durham, NC ■
Uoyd C. McCaskill, M.D., Maxton, NC
Clarence R. McLain, Jr., M.D., Cincinnati,
OH

Andrew C. Miller III, M.D., Gastonia, NC
J. Thaddeus Monroe, Jr, M.D., Chapel Hill, NC
Thomas P Moore, M.D., Jacksonville. NC
G. Irvin Richardson, M.D., Reidsville, NC
Oliver F Roddey Jr. M.D., Charlotte, NC
Robert T Savage, M.D., Winston-Salem, NC
Palmer F Shelbume, M.D., Greensboro, NC
Henry L Stephenson. Jr, M.D., Washington, NC
Robert L Summerlin, Jr., M.D., Dublin, NC
G. ReginakJ lUcker, Jr., M.D., EmeraM Isle,
NC

William J. Waddell, M.D., Prospect, KY
W. Wallace White, M.D., Cincinnati, OH

CLASS OF 1956
Number in Class: 49
Percent Donors: 84%

John R. Baggett III. M.D.. New Bern. NC
Richard A. Boyd, M.D^ Statesville, NC
Wade M. Brannan, M.D., Port Arthur, IX

Thomas E. Castelloe. M.D.. Raleigh. NC

Lee A. Clari<, Jr. M.D., Wilson, NC

John W. Deyton, Jr, M.D., Jacksonville, NC

Margareta J. Duncan, M.D., Dunn, NC

Stacy Allen Duncan, Jr., M.D., Dunn, NC

L-aurence E. Earley, M.D., Gig Hartx)r, WA

William E. Easterling, Jr., M.D., Chapel Hill,

NC

John T Evans, M.D., Chattanooga, TN

Charles W. Fowler III, M.D.. Oriando, FL

Alexander F Goley, M.D., Buriington, NC

Francis W. Green, M.D., Albemarle, NC

William R. Harris, M.D., Hickory, NC

John L Hazlehurst III, M.D., Asheville, NC

Robert P Holmes III, M.D., New Bem, NC

Dean C. Jones, Jr, M.D., Jefferson, NC

H. Neill Lee, Jr., M.D., Lumberton, NC

Clyde F Uoyd, M.D., Roanoke, VA

Otis M. Lowry, M.D,, Spring Hope. NC

Milton B. Mann, M.D., Jacksonville, FL
Marvin M. McCall III, MD., Monroe, NC
V/ilUam W. McLendon, MJi^ Chapel Hill,
NC

Robert L Murray, M.D^ Roanoke, VA
John W. Ormand. Jr., M.D.. Wilmington, NC
Clifton G, Payne, MD., Reidsville, NC
Thomas W. Payne, MD., Newport Nevre, VA
Francis D. Pepper, Jr., M.D., Winston-
Salem, NC

Carey J. Peny, MD., Louisbupg, NC
William R. Purcell, M.D., Laurinburg, NC
James F. Richards, Jr., M.D., Orlando, FL
Joseph I. Riddle, M.D., Morganton, NC
W. R. Stafford, Jr., M.D., Greensboro, NC
Tliomas C. SuUier, Jr, M.D., McCain, NC
John W. Vassey, MD., Raleigh, NC
M. Mickey Vitols, MD., Seattte, WA
Garland E. Wampler, M.D., Buntsville, NC
William B. Wood, M.D., Chapel Hill, NC
Leonard S. Woodall, MD., PA Smittifield, NC
Dewey H. Yartey, MD., Durham. NC

CU\SS OF 1957
Number in Class: 50
Percent Donors: 46%
H. John Bradley, Jr., M.D., Greensboro, NC

James. R. Clapp, M.D., Durtiam, NC
Robert S. Cline, M.D., Sanford, NC
Luther H. Clontz, M.D., Morganton, NC

William P Cornell, M.D., Phoenix, AZ

John K. Farrington, M.D., High Point NC

Eric L Feanington, M.D., Greenville, NC

J. Grayson Hall, M.D., Dobson, NC

Bennett A. Hayes, Jr., M.D., Fayetteville, NC

Jack B. Hobson, M.D., Charlotte, NC

J. Paul Hurst, Jr., MD., Rydal, PA

George L. Irvin III, M.D., Coral Gables, FL

Richard V. Ules, Jr., M.D., Albemarle, NC

H Maxwell Monison, Jr, M.D., Southern Rnes, NC

Harvey A. Page, MD., Rkeville, KY

Thaddeus H. Pope, Jr, M.D., Indianapolis, IN

Raeford T Pugh, MD., Washington, NC

Nathaniel L. Sparrow, M.D., Raleigh, NC

James H. M. Thorp, M.D., Rocky Mount, NC

Gerald M Wagger, M.D., Palo Alto, CA

Eart R Welch, Jr., M.D., Winston-Salem, NC

Robert T. Whitlock, MD., Easton, MD

Dr. Benson R. and Mrs. Uicinda Holdemess Wilcox,

Chapel Hill, NC

CLASS OF 1958
Number in Class: 47
Percent Donors: 38%
Clarence A. Bailey, Jr., M.D., Durham, NC

John I. Brooks, Jr, M.D., Tartxiro, NC

DavkJ B. Crosland, M.D., ML Pleasant, NC

James R. Edwards, MJ)., Raleigh, NC

George E Ennis, MD , Hickory, NC
Nancy P Fawcetl MD , Pembroke Pines, FL
Thomas M Haizlip, MD., Raleigh, NC
John S Howie, MD . Raleigh, NC
Dan E. Johnson, M.D., Concord, NC
Walter N Long, Jr, MD , Taylorsville, NC
John A. McGee, Jr, MD., Chariotle, NC
Luther S. Nelson, M.D., Amarilk), TX
T Lane Ormarxj, MD , Monroe, NC

J. Rk:hard Patterson, M.D., Danville, VA

Charies W. Phillips, Jr., M.D., Gibsonville, NC
Charies W Stout M.D., Asheboro. NC

B. Everett Thompson, Jr, M.D.. Gary, NC
Paul M. Weeks, M.D., Chapel Hill, NC

CLASS OF 1959
Number in Class: 41
Percent Donors: 46%
Doris B. Braxton, M.D., Burlington, NC
Robert C. Brown, M.D., Chapel Hill, NC
Daniel Whitaker Davis, M.D., Wadestxsro, NC
A. Eugene Douglas, Jr, M.D., Bald Head Island, NC
Otis N. Fisher, Jr., M.D., Greensboro, NC
Joel S. Goodwin, M.D., Salisbury, NC
Robert L Green, Sr., M.D., Winston-Salem,
NC

O. James Hart, Jr., M.D., Mocksville, NC
Morris A. Jones, Jr., M.D., Chapel Hill, NC
DavKl L Kelly, Jr., M.D., Winston-Salem, NC
Edward L Mitchell, M.D., Prospect, KY
A. Sherman Morris, Jr., M.D., Asheville, NC
W. Russell Rowland, M.D., Greer, SC
Julian W. Selig, Jr., M.D., Elizabeth City, NC
Martha K. Sharpless, M.D., Greensboro, NC
Shahane R. Taylor, Jr., M.D., Greensboro,
NC
Charies E Trado, Jr., M.D., Hickory, NC

C. Cari Warren, Jr., M.D., Charlotte, NC
R. Lee West, M.D., Greenville, NC

CU\SSOF1960
Number in Class: 60
Percent Donors: 43%
William B. Abemethy, Jr., M.D., Gastonia,
NC

Charies P Ekjridge, Jr., M.D., Houston, TX
Gerald W. Femald, M.D., Chapel Hill, NC
Charies E. Frtzgerakj, Jr., M.D.. Maitland, FL
J. Thomas Fox, Jr., M.D., Valle Cnicis, NC
David B. Garmise, M.D., Bluffton, SC
James R. Harper, Sr., M.D., Durfiam, NC
Falls I- Harris, M.D., Greenville, SC
G. WycMiffe Hoffler, M.D., Trtusville, FL
L Gordon Kirschner, M.D., Washington, DC
E. Carwile LeRoy, M.D., Charleston, SC
James M Mariowe, M.D., High Point NC
J. Gray McAllister III, M.D., Chapel Hill, NC
K. Franklin McCain, M.D., Winston-Salem,
NC

Cecil H. Neville, Jr., M.D., Pinehurst, NC
Duncan S. Owen, Jr., M.D., Richmond, VA
Rotert B. Payne, MD., Mooresville, NC
Jerry M. Petty, M.D., Charlotte, NC
Jean R Poirier, MD , Frederick, MD
Elizabeth V. Raft, M.D., Durttam, NC
G Thomas Strckland, Jr, M.D., Baltmore, MD
Joseph E. Swanton, M.D., Roanoke Rapids,
NC

John C Tayloe, MD., New Bem, NC
H Mac Vandiviere, MD, LarKaster, KY
P Burt Veasey, M.D., Sarasota. FL
John A Young, MD.. Chariotte, NC

CLASS OF 1961
Number in Class: 49
Percent Donors: 76%

E Stanley Avery, Jr, M.D., NortolK VA

Robert M. Boemer, M.D., Asheville, f^JC

Charies 0. Boyette, Sr., M.D., Belhaven. NC

R. Cari Britt MD.. Chapel Hill, NC

William L Brown, M.D., Roanoke Rapids, NC

H. Davkl Bruton, M.D., Cartilage, NC

John C Council, Jr., M.D.. Chariotte, NC

Robert K. Creighton, Jr.. M.D., M.RH., Wilmington.

NC

Cosmo A. Difazio, M.D., Ph.D., Chariottesville, VA

John W. Garden. M.D., Lexington. KY

William S. Gibson. Jr.. M.D., Riverside, PA

John C. Graham, Jr., M.D., Kitty Hawk, NC

Claud M. Grigg, M.D., Chariotte, NC

L Morgan Hale, MD.. Chapel Hill. NC

Richard W. Hudson. M.D.. Bayboro, NC

Richard D. Jordan. M.D.. Salisbury, NC

William H. Kouri, M.D., Isle of Palms. SC

Lloyd D. Lohr. M.D., Lexington. NC

Zell A. McGee, MD., Salt Lake City, LTT

W. Stacy Miller. M.D., Raleigh. NC

William W. Morgan, Jr., M.D., Reno. NV

A. Ray Newsome. M.D., Winston-Salem. NC

C. Rex O'Briant M.D.. Gilbert, AZ

William L Owens, M.D., Clinton, NC

Louie L. Patseavouras, M.D., Greensboro,

NC

Cecil H. Rand. Jr.. M.D., Greenville. NC

Leonard E Reaves III. M.D., Menv Hill, NC

Bobby A. Richardson, M.D., Ocala, FL

James H. Robinson, M.D., Wilmington. NC

W. Ray Samuels, M.D., Kiawah Island, NC

Edward A. Sharpless, M.D., Greensboro,

NC

W. Fenell Shuford, Jr, M.D., Wilmington, NC

Joshua Taytoe, M.D., Washington, NC

Stephen J. Trachtentjerg, M.D., Huntington Station,

NY

Zebulon Weaver III. M.D., Asheville, NC

Donn A. Wells, M.D., Sea Ranch Lakes, FL

William H. White, Jr., M.D., Sanford, NC

CLASS OF 1962
Number in Class: 51
Percent Donors: 47%

Kart L Bartdey M.D.. Greensboro, NC

Oscar H. Bofch, Jr., M.D., San Diego, CA

Joseph H. Callicott Jr. M.D.. Lynchburg. VA

Lawrence M. Cutchin, M.D., TarlMro, NC

Jeny J. Eller. M.D., Livingston, AL

A. Ray Evans, M.D.. Greenville. NC

Thomas W Gable. M.D.. Atlanta. GA

Marion W Gnffin, M D.. Asheboro, NC

H. Gerard Hartzog III, M.D., Raleigh, NC

Dr. and Mrs. Ray M. Hayworth, KitoxviUe,

TN

Charies M. Hicks, MD., Wihiington, NC

Arthur S Lynn, Jr , M.D., Conover, NC

J Newton MacCormack. MD , Raleigh, NC

John L. Monroe, M.D., West End, NC

Kenny J. Morris, M.D., Wilmington, NC

William A Nebel, MD , Chapel Hill, NC

Carl S. Phipps, M.D., Winston-Salem, NC

Alton A. Reeder, M.D., High Point, NC

J. Flint Rhodes, M.D., Raleigh, NC

Lambros C Rigas, MD , Rome, GA

Fuller A Shuford, MD , Asheville, NC

29

Roy V. Vamer, M.D., Houston, TX
David T. Watson, M.D., Atlanta, GA

Abner C. Withers, M.D., Salisbury, NIC

CLASS OF 1963
Number in Class: 50
Percent Donors: 40%
William R Algary, M.D., Greenville, SC
Dr. and Mrs. Neil C. Bender, New Bern, NC
I. Kelman Cohen, M.D., Richmond, VA
Robert J. Cowan, M.D., Winston-Salem, NC
William B. Deal, M.D., Bimiingham, AL
J. Michael Gallagher, M.D., Seattle, WA
J. Phillip Goodson, M.D., Raleigh, NC
Ira M. Hardy II, M.D., Greenville, NC
William O. Jolly III, M.D., Albemarle, NC
Charles I. Loftin III, M.D., Roanoke, VA
J. Marshall McLean, M.D., Peoria, IL
James L Partner, M.D., Hickory, NC
Richard 1- Pressley, M.D., Advance, NC
Charles J. Sawyer III, M.D., Ahoskie, NC
Richard W. Shermer, M.D., Chapel Hill, NC
David W. Sillmon, M.D., Greenstwro, NC
Jeny A. Smith, M.D., Memphis, TN
William E. Thomton, M.D., Fair Oaks Ranch, TX
Roy A. Weaver, M.D., Fayetteville, NC
David R. Williams, Sr., M.D., Thomasville,
NC

CLASS OF 1964
Number in Class: 53
Percent Donors: 28%

J. Nichols Beard, M.D., Charlotte, NC

Hany L Broome, M.D., Alpharetta, GA

John R. Cella, M.D., Raleigh, NC

James F Earnhardt, M.D., Winston-Salem, NC

Clyde M. Gaffney III, M.D.. Greer, SC

G. Patrick Henderson, Jr., M.D., Southem Rnes, NC

D. Charles Hunsinger, M.D., Salter Path, NC

E. Woodrow Hunt Jr., M.D., La Jolla, CA

W. Kirby Kilpatrick, Jr, M.D., Pinehurst, NC

Noel B. McDevitt, M.D., Southem Pines, NC

Artus M. Moser, Jr., M.D., Swannannoa, NC

Robert J. Pierce, Jr.. M.D., Hickory, NC

Marshall E. Redding, M.D., Long Beach, CA

James W. Rose, Jr., M.D., Madison, Wl

Robin N. Woolen, Jr., M.D., Lakeland, FL

CLASS OF 1965
Number in Class: 56
Percent Donors: 29%

L Bernard Branch, M.D., Lexington, KY
Daniel E. Brown, M.D., Raleigh, NC
Hal F Collier, M.D., Rowery Branch, GA
Takey Crist, M.D., Jacksonvilte, NC
Robert L Grubb, Jr., M.D., Glendale, MO
Howard HoWemess, Jr., M.D., Greenstxiro, NC
Joe P Hurt M.D., Ph.D., Sylva, NC
Robert T. Kindley, M.D., Mary Esther, FL
Richard E. Lassiter, M.D., Chapel Hill, NC
Gordon B. LeGrand, MD., Raleigh, NC
Sue E. Massey, M.D., Scotis Valley, CA
Donald D. McNeill, Jr., M.D., Lenoir, NC
Thomas L Presson, M.D., Greensboro, NC
William F. Sayers, M.D., Winston-Salem, NC
Evin H. Sides III, M.D., Raleigh, NC
Williamson B. Strum, M.D., La Jolla, CA

CLASS OF 1966
Number in Class: 58
Percent Donors: 76%
J. Curtis Abell, M.D., Statesville, NC

Robert P Bamnger, M.D., Gastonia, NC

Robert H. Bilbro, M.D., Raleigh, NC

William H. Bowers, M.D., Richmond, VA

Paul L Bunoughs, Jr., M.D., Raleigh, NC

Timothy E. Cbninger, M.D., Chariotte, NC

George W. Cox, M.D., Atlanta, GA

John R. Crawford III, M.D., Salisbury, NC

J. Bernard Credle, M.D., Beaufort SC

William M. CratchfieM, M.D., Elizabeth City,

NC

Philip C. Deaton, M.D., Greensboro, NC

Wesley C. Fowler, Jr., M.D., Chapel Hill, NC

Edgar C. Garrabrant II, M.D., Raleigh, NC

Robert C. Gibson III, M.D., Portland, OR

Cyais L Gray III, M.D., Hiawassee, GA

Carol H. Hackett, M.D., BelMew, WA

Lawrence D. Henry, M.D., Jefferson City,

MO

Howard T Hinshaw, M.D., Chariotte, NC

N. Neil Howell, M.D., Chariotte, NC

Elizabeth S. Hoyt M.D., Gary, NC

William C. Hubbanl, M.D., Raleigh, NC

Stanleigh E. Jenkins, Jr., M.D., Ahoskie, NC

Sidney C. Kress, M.D., Staten Island, NY

Thomas J. Koonb, M.D., Winston-Salem,

NC

Hugh A. McAllister, Jr., M.D., Houston, TX

Edgar M. McGee, M.D., Lexington KY

Peter L Morris, M.D., Santa Barbara, CA

Duncan Morton, Jr., M.D., Chariotte, NC

Hugh G. Mun:ay Jr., M.D., Atlanta, GA

R. Kenneth Pons, M.D., Medford, OR

Don W. Printz, M.D., Stone Mountain, GA

Surry P Roberts, M.D., Raleigh, NC

Charies K. Scott M.D., Haw River, NC

Robert E. Sevier, M.D., Greenstmro, NC

J. Lewis Sigmon, Jr., M.D., Davidson, NC

Robert G. Simmons, M.D., Pittsboro, NC

H. Lee Smyre, M.D., Greer, SC

E. Walker Stevens, Jr, M.D., Greensboro, NC
Donald A. Thomas, M.D., Seneca, SC
Henry F Thomas, Jr, M.D., Gastonia, NC

W. Beverly TUcker III, M.D., Henderson, NC
W. Hunter Vaughan, M.D., Steubenville, OH
James H. Whicker, M.D., Raleigh, NC
James A. Yount, M.D., Charlotte, NC

CLASS OF 1967
Number in Class: 64
Percent Donors: 45%

Phillip G. Arnold, M.D., Rochester, MN

F. Walton Avery, M.D., Chapel Hill, NC
Gerald W. Blake, M.D., Raleigh, NC

Thomas W. Bundy, M.D., Chambersburg, PA
Vartan A. Davklian, Jr., M.D., Raleigh, NC
C. Allan Eure, M.D., Raleigh, NC
R. Donald Garrison, M.D., Jacksonville, FL
Harvey J. Hamrick, M.D., Chapel Hill, NC
E. Franklin Hart, Jr., M.D., Morganton, NC
James D. Hundley, M.D., Wilmington, NC
Linda H. Jackson, M.D., Arden, NC
William H. Jarman, Jr, M.D., Gastonia, NC
Scott G. Kleiman, M.D., Marietta, GA

Hugh T Letter, Jr, M.D., Fort Worth, TX
Philip R. Littleton, M.D., Buri<e, VA
Robert W. Madry, Jr., M.D., Corpus Christi,
TX

W. Jason McDaniel, Jr., M.D., Raleigh, NC
Joseph T McLamb, M.D., Goldstmro, NC
HaroM B. Owens, M.D., Danville, VA
GeraM Pelletier, Jr., M.D., New Bern, NC
Bmce A. Phillips, Jr, M.D., Elizabethtown, NC
Albert L Roper II, M.D., Norfolk, VA
Douglas M. Russell, M.D., Goklsboro, NC
Walter R. Sabiston, M.D., Kinston, NC
James H. Spruill, M.D., Jackson, TN
Henry C. Thomason, Jr., M.D., Gastonia, NC
M. Dennis Wachs, M.D., Bedford, NH
Bei^min K. Ward, Jr., M.D., Florence, SC
Bany M. WellDome, M.D., Chariotte, NC

CLASS OF 1968
Number in Class: 59
Percent Donors: 37%
Joseph R Archie, Jr., M.D., Raleigh, NC
George W. Bensch, M.D., Stockton, CA
I. Alan Craig, M.D., Skyland, NC
Alan Davidson III, M.D., Greensboro, NC '
Teny D. Golden, M.D., Atlanta, GA
Theodora L Gongaware, M.D., Savannah, GA
Joseph W. Griffin, Jr., M.D., Augusta, GA
William O. Kearse, Jr, M.D., Lubbock, TX
John L Kirl^land III, M.D., Houston, TX
Edward W. Kouri, M.D., Chariotte, NC
Jerold E. Lancourt, M.D., Dallas, TX
Patrick T Malone, M.D., Atlanta, GA
Rutherford B. Polhill, Jr, M.D., Bimningham, AL
David J. Reese II, M.D., Atexandria, VA )

David M. Rubin, M.D., Greensboro, NC
Carole W. Samuelson, M.D., Bimiingham, AL
E. Franklin Shavender, M.D., Durtiam, NC
George S. Stretcher, M.D., Spartanburg, SC
Jack G. Wall, M.D., Graham, NC
J. Allen Whitaker III, M.D., Wilson, NC
Roberta G. Williams, M.D., La Canada, CA
Jerry C. Woodard, M.D., Wilson, NC

CLASS OF 1969
Number in Class: 62
Percent Donors: 44%
H. Wallace Baird, M.D^ Greensboro, NC
J. Hugh Bryan, M.D., Fayetteville, NC
W. Woodrow Bums, Jr., M.D., Chapel Hill,
NC

Don C. Chaplin, M.D., Buriington, NC
Bertram W. Coffer, M.D., Raleigh, NC
R. Samuel Cromartie III, M.D., Ormond Beach, FL
Eugene B. Ferris, M.D., Vcksburg, MS
Hugh J. Grant Jr., M.D., Raleigh, NC
Thomas R. Griggs, M.D., Hillsborough, NC
G. Patrick Guiteras, M.D., Chapel Hill, NC
Edward W. HaseMen, Jr., M.D., Columbia,
SC

J. Thomas John, Jr, M.D., Nashville, TN
John G. Johnston, M.D., Chariotte, NC
Dr. and Mrs. William A Jordan,
Fayetteville, NC

Richard A. Keever M.D., High Point NC
Henry J. MacDonald, Jr., MJ}., New Bern,
NC

30

R. James MacNaughton, Jr., M.D.,
Greenville, SC

Donald M. MacQueen III, M.D.. Wilmington, NIC
Cynttiia S^ McMillan, M.D., Farragut TN
David W. Pearsall, Jr, M.D., Greenville, NC
David S. Sheps, M.D., Gainesville, FL
James W. Snyder, M.D., Wilmington, NC
Kar«n C. Sorrels, M.D., Midlothian, VA
Franklin T. Tew, M.D., Chapel Hill, NC
John C, Tnplett, M.D., MPH., Bettiesda, MD
Nelson B. Watts, M.D., Atlanta, GA
C. Thomas Whiteside, M.D., Mt Reasant, SC

CLASS OF 1970
Number in Class: 70
Percent Donors: 41%
William C. Allsbrook, Jr.. M.D,, Martinez, GA
Jerry C. Bernstein, M.D., Raleigh, NC
Rot3ert G. Blair, Jr., M.D., New Bern, IMC
Harold H. Cameron, M.D., Nev* Bern, IMC
Bnjce S. Chang, M.D., Lx)uisville, KY
Daniel L. Crocker, Jr., M.D., Rocky Mount,
NC

Charles E. Crumley, M.D., Uncalnton, IMC
H. Shelton Earp III, M.D., Chapel Hill, NC
Richard M. Freeman, M.D., Opelika, AL
James O. Goodwin, M.D., Henderson, NC
Joseph M. Harmon, M.D., Charleston, SC
John F. Hartness, Jr, M.D., Monroe, NC
W. Borden Hooks, Jr., M.D., Mount Airy, NC
Dr. and Mrs. Mark G. Janis, Seal Beach, CA
C Bryan Koon, Jr., M.D., Durham, NC
Frederick G. Kroncke, Jr., M.D., Rocky
Mount, NC

Thomas W. Nicholson, M.D., Bath, NC
Edward A. Norfleet, M.D., Chapel Hill, NC
Martha E. Parker, M.D., Asheville, NC
David A. Rendleman III, M.D., Raleigh, NC
James B. Sk>an, M.D., Wibnington, NC
James D. Smilhwick, M.D., Laurinburg, IMC
Charles E. Thompson, M.D., New Rochelle,
NY

J. Reed Underhill, M.D., New Bern, NC
Ross L. Vaughan, M.D., Raleigh, NC
E. Lance Walker, M.D., Littleton, CO
William J. Weatherly, M.D., Greensl>oro, NC
H. Grey Winfiekj III, M.D., Hickory, NC
John W. Zirkle, M.D., Jefferson City, TN

CLASS OF 1971
Number in Class: 68
Percent Donors: 46%

Carol K. Aschenbrener, M.D., Washington, DC
J. Rcfiard Auman, M.D.. Chesapeake, VA
Robert A. Bashford, M.D., Chapel Hill, NC
James S Coxe III, M.D., Raleigh, NC
Edwin G. Faneil, MD , Greenstwro, fMC
Michael J. Fekjman, M.D., Edina, MN
Bertram C, Finch III, MD . Charleston. SC
James S. Fulghum III, M.D., Raleigh, NC
Mary Susan Fulghum, M.D., Raleigh, NC
Joe E Gaddy, Jr, MD , Winston-Salem, NC
Daniel P Greenfield, M.D., Short Hills, NJ
Michael R. Knowles, M.D., Chapel Hill, NC
Robert L. Kuykendal, M.D., Cincinnati. OH
William A Lambeth III, MD , Raleigh, NC
Donald V. Lewis, MD., Cooperstown, NY

Jonathan 0. McLean. M.D., Charlotte, NC
Frederick S. Neuer, M.D., Emporia, KS
William B. Pittman, M.D., Rocky Mount, NC

R. Randolph Powell, M.D., Fox Point, Wl
John 0. Reynolds, Jr, M.D., Salisbury, NC
Charles H. Richman, M.D., Saratoga
Springs, NY

Roy H. Schindelheim, MD.. King City, CA
James A Scovil, Jr, M.D., Raleigh, NC
J. Allison Shivers, M.D., Asheville, NC
Sara H. Sinai, M.D., Winston-Salem, NC
John R Surratt, M.D., Clinton, NC
J. R Van Dorsten, M.D., Charleston, SC
George C. Venters, M.D., Raleigh, NC
[Xvight W. Wait III, M.D., Charlotte, NC
William W. Webb, Jr, M.D., Salisbury, NC
Blane W. Yelton, Jr, M.D., Thomasville, NC

CLASS OF 1972
Number in Class: 65
Percent Donors: 32%

Robert L Bames III, M.D., Knoxville, TN

Myron H. Brand, M.D., Madison, CT

Peter R. Bream, M.D., Jacksonville, FL

L Franklin Cashwell, Jr, M.D., Greensboro, NC

Peter G. Chikes, M.D., Concord, NC

Randolph B. Cooke, M.D., Owego, NY

Alger V Hamrick III, M.D., Raleigh, NC

L. Clayton Harreil III, M.D., Chariotte, NC

Sampson E. Han-ell, M.D., Durham, NC

F. Christian Heaton, M.D., Raleigh, NC
John T. Henley, Jr., M.D., Fayetteville, NC
William B. Horn, M.D., Boone, NC

John S. Hughes, M.D., New Haven, CT
Joseph A. Jackson, M.D., Pibt Mountain, NC
Howard S. Kroop, M.D., Woodbury, NJ
William E. Long, M.D., Newton, NC
John R. Lurain III, M.D., Oak Pari(, IL
John T. Manning, Jr., M.D., Houston, TIC
James S. Reed, M.D., Gig Harbor, WA
Ronald J. Stanley, M.D., Boone, NC

G. Dean Wilson, Jr, M.D., Johnson City, TN

CLASS OF 1973
Number in Class: 79
Percent Donors: 29%

G. Ruffin Benton III, M.D., Brevard, NC

Stephen B, Billick, M.D., New York, NY

Frank E. Davis III, M.D., Roanoke Rapids, NC

Charies H. Edwards II, M.D., Chariotte, NC

John E. Estes, Jr, M.D., Rocky Mount, NC

E. Ruffin Franklin, Jr, M.D., Raleigh, NC

Teny L Fry, MD., Georgetown, SC

DonakJ B. Goodman, Jr, M.D., Charlotte, NC

Davki A. Grimes, M.D., Chapel Hill, NC

J. Michael Harper, MD., Charlotte, NC

Larry A. High, Jr, M.D., Rocky Mount. NC

Dennis R Johnson, MD , York. PA

E. EaH Jenkins, Jr^ M.D^ Rock Hill, SC

J. Chartes Jennette, M.D., Chapel Hill, NC

Elisatieth Anderson Keller, M.D., Brookline. MA

James L. Maynard, M.D., Rock Hill, SC

Dale A. Newrton, M.D., Greenville, NC

Davkl R. Patterson, M.D., Greensboro, NC

W, Henry Purvis, M.D., Sanford, NC

W. McLean Reavis, Jr., M.D., Lakeland, FL

David E. Sharp, M.D., Ph.D., Bear Creek, PA

George H. Underwood, Jr. M.D., Honolulu, HI
Robert R. Walther, M.D., New Yoric, NY

CLASS OF 1974
Number in Class: 93
Percent Donors: 35%
Robert M. Alsup, M.D., Winston-Salem, NC

Charles B. Beasley, M.D., Kinston, NC

Thomas W. Boukjin, M.D., Chapel Hill, NC

William E. Bovmian, M.D., Greenstwro, NC

Donald C. Brown, M.D., Gary, NC

David R. Clemmons, M.D., Chapel Hill, NC

George W. Colclough, M.D., Lexington, KY

Paul M. Deaton, Jr., M.D., Charleston, SC

Marshall M. Feaster III, M.D., Wyomissing, PA

Margaret A. Harper, M.D., Winston-Salem, NC

Lynn D. Ikenberry, M.D., Chapel Hill, NC

Joseph M. Jenkins, M.D., Fayetteville, NC

Kenneth R. Kulp, M.D., Raleigh, NC

John A. Lang III, M.D., Raleigh, NC

William D. Lee, Jr., M.D., Raleigh, NC

Clarence E. Uoyd, Jr, M.D., Greensboro, NC

Sheppard A. McKenzie III, M.D., Raleigh,

NC

William H. Moretz, M.D., Auguste, GA

Paul L Ogbum, Jr, M.D., Rochester, MN

H. Clifton Patterson III, M.D., Raleigh, NC

HaroM C. Pollard III, M.D., Winson-Salem,

NC

Thomas W. Powell, M.D., Concord, NC

C. Fredric Rekl, M.D., Winston-Salem, NC

David A. Rockwell, M.D., Goldsboro, NC

Suzanne V Sauter M.D., Chapel Hill, NC

Charles W. Smith, Jr, M.D., Little Rock. AR

Roger L. Snow, M.D., Boston. MA

David E. Tart, M.D., Hickory, NC

David T. Tayloe, Jr., M.D., GoMsboro, NC

John W. Thornton III, M.D., Augusta, GA

Kenneth H. Wilson, M.D., Chapel Hill, NC

William G. Wilson, M.D., Charlottesville, VA

Charies D. Yoder, M.D., Fairview, NC

CLASS OF 1975
Number in Class: 101
Percent Donors: 35%

Vaughn R Arey M.D.. Galax, VA
Bruce A. Berlow. M.D., Mystic, CT
William J. BlacMey, M.D., Elkin, NC
Sherif C. Botros, M.D., Wilmington, NC

Patrick G. Bray, M.D., Shaker Heights, OH
Samuel L. Bridgers II, M.D., Woodbridge,
CT

Benjamin Douglas, M.D., DillstxDro. NC
William H. Edwards, M.D., Norwich, VT
Richard F. Fox, M.D., Greenstwro, NC
M. Dan^ Fuller, Jr, M.D., Las Cruces. NM
DonaM G. Gregg, M.D., Greenville, SC
Eric H Helsabeck, M.D., Asheboro, NC
Emest F Knjg III, M D., Rochester, Ml
Charles P Langley III. MD , Shelby, NC
David S Lennon, MD.. Chariotte, NC
Howard A. McMahan, M.D., Marietta, GA
Michael W, Menwether, M.D., Sarasota, fl-
Frank H, Moretz, M.D., Asheville, NC
Wade H Moser, Jr. MD,, Raleigh, NC
Dan A. Myers, M.D., Kinston, NC
W. RonaM Neal, M.D., Greensboro, NC

Henry N. Nelson III, M.D., Indialantic, FL
Lanning R. Newell, M.D., Raleigh, NC
Henry E. Parfitt, Jr, M.D., Fayetteville, NC
James E. Peacock, Jr., M.D., Winston-Salem, NC
Joseph B. Philips III, M.D., Birmingham, AL
Hoke D. Pollock, M.D., Wilmington, NC
James L Price III, M.D., Wilmington, NC
Pamela S. Rand, M.D, Santa Monica, CA
W. Paul Sawyer, M.D., Tallahassee, FL
Kenneth K. Steinweg, M.D., Greenville, NC
Suzanne Tropez-Sims, M.D., Brentwood, TN
Hendricks H. Wliitinan ill, M.D., New
Vernon, NJ

James W. Winslow, M.D., Tartioro, NC
Kenneth H. Winter, M.D., Greenslx>ro, NC

CLASS OF 1976
Numlier in Class: 117
Percent Donors: 43%

Brenda L Adams-Hudson, M.D., Moore, SC

Janet Cybrynski Aiken, M.D., Gastonia, NC

Warwick Aiken III, M.D., Gastonia, NC

Paul D. Barry, M.D., Greensboro, NC

Rotjert R. Bass, M.D., Annapolis, MD

W. Bryson Bateman, Jr., M.D., Goldsboro, NC

Martin F Beals, Jr, M.D., Bluefield, VA

.lean C. Bolan, M.D., Washington, DC

Alexis C. Boutenetf, M.D., Litchfield, CT

Richard A. Bowerman, M.D., Ann Artxir, Ml

Barbara J. Campt)ell, M.D., Somerset, PA

Marjorie B. Can-, M.D., Raleigh, NC

Cornelius F. Cathcart, M.D., Henderson, NC

Edward L Cattau, Jr., M.D., Germantown

IN

Susan T. Edwards, M.D., Norwich, VX

Catherine J. Everett, M.D., New Bern, NC

William H. Gamble, M.D., Greensboro, NC

Rita L Gunter, M.D., Fayetteville, NC

Charles H. Hicks, M.D., Wrightsville Beach, NC

J. Lee Hotter, M.D., Temple, TX

Robert H. Hutchins, M.D., Wilmington, NC

Adrian E. Long, M.D., Ruxton, MD

Ross D. Lynch, M.D., Columbia, SC

McKay McKinnon, M.D., Kenilworth, IL

B. Douglas Morton III, M.D., Macon, GA

Robert S. Moskalik M.D., Coldwater, Ml

E. Paul Nance, Jr., M.D., Nashville, TN

I- Andrew Nassef, Jr., M.D., Danville, PA

David B. Neeland, M.D., Montgomery, AL

Harold A. Nichols, M.D., Greenstxiro, NC

Kathleen Gallagher Oxner, M.D.,

Greenville, SC

Unn H. Parsons, M.D., Winston-Salem, NC

James S. Parsons, M.D., Raleigh, NC

V. Edgar Raul, M.D., Greensboro, NC

Chartes V. Pope, M.D., Apex, NC

Douglas C. Privette, M.D., Greenville, NC

Sheldon M. Retchin, M.D., Richmond, VA

Robert S. Shapiro, M.D., Athens, GA

David F Silver, M.D., Chariottesville, VA

Unnea W. Smith, MD., Chapel Hill, NC

Grady M. Stone, M.D., High Point NC

Robert J. Tallaksen, M.D., Morgantown, WV

R. Henry Temple, Jr, M.D., Wilmington, NC

F. Ray Thigpen, M.D., Whiteville, NC
John W. Uribe, M.D., Coconut Grove, FL
Nancy E. Wight, M.D., San Diego, CA

Moses E. Wilson, Jr, M.D., Rocky Mount NC
Richard L Wing, M.D., Chariotte, NC
Sabra A. Woodard, MJ>^ Raleigh, NC
SokNTHMi G. Zerden, M.D., Savannah, GA

CL^SSOF1977
Numlier in Class: 113
Percent Donors: 27%

Michael L Barringer, M.D., Shelby, NC

Clinton A. Briley, Jr, M.D., Wrightsville Beach, NC

David L Call, M.D., Eden, NC

Francis S. Collins, M.D., Ph.D., Rockville,

MD

Joseph E. Craft M.D., Hamden, CT

Allen J. Daugird, M.D., Chapel Hill, NC

Wayne D. Fogle, M.D., Knoxville, TN

William L Isley, M.D., Overland Pari<, KS

George M. Johnson, M.D., Charleston, SC

Judith M. Kramer, M.D., Chapel Hill, NC

Frederick H. Mabry, Jr, M.D., Laurinburg, NC

S. Ray Mitchell, M.D., Alexandria, VA

Warren H. Moore, M.D., Sugar Land, TX

H. Grady Morgan, Jr., M.D., Wilmington, NC

Pamela A. Nelson, M.D., Raleigh, NC

Melinda C Paul, M.D., Greensboro, NC

Ruth C. Penn, M.D., Eldersburg, MD

R Lee Peridns, M.D., Shelby, NC

Michael L Pool, M.D., Knoxville, TN

Duncan S. Poslma, M.D., Tallahassee, FL

Robert B. Price, M.D., Marietta, GA

Catherine M. Radovich, M.D., Gallup, NM

Gbria M. Rapoport M.D., Forest Hills, NY

William H. Ryan III, M.D., Dallas, TX

Samuel T. Selden, M.D., Chesapeake, VA

Howard J. Stang, M.D., Stillwater, MN

John H. Stanley, Jr., M.D., Wilmington, NC

Mathai S. Thomas, M.D., Buriington, NC

Charies F Timmons, Jr, M.D., Dallas, TX

RKhard H. Weisler, M.D. Raleigh, NC

MKhael S. Wheeler, M.D., Rutherfordton,

NC

CLASS OF 1978
Number in Class: 125
Percent Donors: 27%

Michael C. Alston, M.D., Murfreesboro, NC
John D. Benson, M.D., Cary, NC

Jean W. Carter, M.D., Raleigh, NC

William G. Clark, M.D., Wake Forest, NC

Brian J. Cohen, M.D., Sudbury, MA

Paul W. Coughlin, M.D., High Point, NC

Betty J. Crosby, M.D., Chariotte, NC

Allison J. Dudley, M.D., Chariotte, NC

George S. Edwards, Jr, M.D., Raleigh, NC

Marttia L Elks, M.D., Atlanta, GA

Diane S. Harris, M.D., Chapel Hill, NC

Seth V Hetherington, M.D., Chapel Hill, NC

Katharine A. High, M.D., Merion Station, PA

Robert L Hines, M.D., Fayetteville, NC

Dorothy M. Linster, M.D., Raleigh, NC

Luisa A. Lorenzo, M.D., Hendersonville, NC

Wade L Lowiy, M.D., Colleyville, TX

Jeffrey A. Margolis, M.D., TappahannocK VA

Carol A. Martin, M.D., Raleigh, NC

Mark D. Monson, M.D., Spartanburg, SC

Cassandra F Newkiri^ M.D., Belle Mead, NJ

Michael Y. Partner, M.D., Raleigh, NC

Robert W. Patterson, M.D., Sanford, NC
Peter A. Schlesinger, M.D., St Paul, MN
Stuart C. Segerman, M.D., Atlanta, GA
Tfiomas C. Shea, M.D., Chapel Hill, NC
Susan T. Snider, M.D., Spruce Pine, NC
William D. Snider, M.D., Chapel Hill, NC
Kathryn J. Stephens, M.D., Chariotte, NC
Alan D. Stiles, M.D., Chapel Hill, NC
Barry H. Teasley, M.D., Goldsboro, NC
Gregory H. Tuttle, M.D., Chapel Hill, NC
William A. Walker, M.D., Chariotte, NC
RKhard C. Worf, M.D., Winston-Salem, NC

CLASS OF 1979
Number in Class: 123
Percent Donors: 28%

Andrew H. Balder, M.D., Longmeadow MA

H. Robert Brashear III, M.D., Pennington, NJ

R. William Bynum IV, M.D., Wilson, NC

W. Hugh Craft, Jr., M.D., Roanoke, VA

Walter E. Daniel, Jr, M.D., Raleigh, NC

S. Diane Davis, M.D., Cotorado Springs, CO

Douglas M. Delong, M.D., Cherry Valley, NY

F Andrew Don-, M.D., Solana Beach, CA

Elizabeth A. Eagle, M.D., Greensboro, NC '

Ellen B. Fitzgerald, M.D., Lexington, KY

Sharon M. Foster, M.D., Raleigh, NC

R. TTiad Goodvnn, M.D., Fort Myers, FL

Charies O. Hanis, M.D., Chapel Hill, NC

Micfiele A. Hines, M.D., Fayetteville, NC

M. Catherine Schumacher, M.D.,

Anchorage, AK

Anne T Kelfer, M.D., Chapel Hill, NC

John C. Keifer, M.D., Chapel Hill, NC

John M. Lafferty, M.D., Vaklese, NC

Julia E. McMurray, M.D., Madison, Wl

Darlyne Menscer, M.D., Chariotte, NC

Susan Pate, M.D., Raleigh, NC

Lawrence H. Pearson, M.D., Shelby, NC

Alan M. Rauch, M.D., Santa Bart)ara, CA

J. Mark Rowles, M.D., Atlanta, GA

James L. Sanderfbrd, Jr., M.D., Lewisville,

NC

David M. Siegel, M.D., Rochester, NY

William L Stewart, M.D., Southern Rnes, NC

R. Mark Stiegel, M.D., Chariotte, NC

Frances R. Thomas, M.D., ChKago, IL

Paul A. Vadnais, M.D., Chartotte, NC

Lynn E. Wesson, M.D., Raleigh, NC

Mack W. White III, M.D., Chariotte, NC

R. Stanford Williams, M.D., Gainesville, FL

Ossian B. Wynn, M.D., Chariotte, NC

CU\SSOF1980
Number in Class: 151
Percent Donors: 26%

Mary R Baucom, M.D., Concord, NC

R. Alan Bell, M.D., Chapel Hill, NC

Edward H. Bertram III, M.D., Chariottesville, VA

Paul J. Betanis, M.D., Melbome, FL

Wilbur B. Carter, Jr, M.D., Chapel Hill, NC

Patricia T Edkins, M.D., Chapel Hill, NC

W. Wells Edmundson, M.D., Raleigh, NC

Walter E. Egerton III, M.D., Atjerdeen Proving

Grounds, MD

C. O'Neil Ellis, M.D., Matthews, NC

Barry J. Freeman, M.D., Los Angeles, CA

Jackson V. Gibson, M.D., Southern Pines,
NC

John C. Gudger. MD., Swansboro, NC

David D. Gutterman, M.D., Mitwaukee, Wl

Catherine J. Hanis. M.D., Wilminciton, DE

M. Unda Hawes, MD , Rocky Mount NC

Carl L Haynes, Jr., M.D, Kinston, NC

J. Patrick Holland, M.D., Winston-Salem,

NC

Konrad C. Kaltenbom, M.D., Anchorage,

AK

Christopher M. Lakin, M.D., Charlotte, NC

Daniel M. Lewis, M.D., Charlotte, NC

Jimmy Lxxjklear, M.D., Raleigh, NC

William L Lowe, Jr., M.D., Winnetka, IL

Christine C. Mahvi, M.D., Middleton, Wl

Steven K. McCombs, M.D., Chapel Hill, NC

J. Eugene McMurry, Jr, M.D., Wilmington, NC

T. Michael O'Shea, Jr., M.D., Winston-Salem, NC

Bayanj L Powell, M.D., Winston-Salem, NC

rmothy A. Presnell, M.D., RKhlands, VA

Petrie M. Rainey, M.D., Lake Forest ParK WA

Judith L Rissman, M.D., Lexington, MA

Andrew M. Singer, M.D., Lincoln, MA

James R Sretiro, M.D., Napa, CA

Walter J. Steele, M.D., Charfcrtte, NC

James V. Taylor III, M.D., Wilson, NC

Benjamin D. Thomas, Jr, M.D., Atlanta, GA

Donna W. Tilson, M.D., Louisville, KY

Jonathan P Tolins, M.D., Minneapolis, MN

rmothy A. Viser, M.D., Cleveland, TN

Kenneth W. Wilkins, Jr., M.O., New Bern,

NC

CLASS OF 1981
Number in Class: 1 54
Percent Donors: 39%
G. Williams Adams, M.D., Sevema Park, MD

Lee P Adier, MD., Winston-Salem, NC

Paul S. Andrews, M.D., Chapel Hill, NC

Richanj L Auten, Jr., M.D., Chapel Hill, NC

Elizatieth S. Babcox. M.D., Stiaker Heights, OH

David S. Barnes, M.D., Shaker Heights, OH

Alix L Baxter, M.D., Gainesville. FL

Kenneth R. Blau, M.D., Sarasota, FL

Phillip M. Bridgman. M.D., Hannawa Falls, NY

Graham W. Bullard, M.D., Cornelius, NC

Michael C. Bumette, M.D., Tampa, FL

Lena W. Butterworth, M.D., Chariotte, NC

DavM M. Cowrherd, M.D., Pinehurst, NC

DavM A. Crews, M.D., GreenstMro, NC

William Vance Cuthrell, M.D., Boise, ID

Amelia F. Drake, M.D., Chapel Hill, NC

Willie S. Edwards, Jr., M.D., Ftorence, SC

Kathryn T George, M.D., Towson. MD

David A. Goff, M.D., Raleigh, rc

Teny R, Gordon, M.D., Detroit Ml

David K. Harper, M.D.. Concord, NC

William M. Hemdon, Jr., M.D., Chariotte, NC

M Bradford, Huggins, MD , Corxsver, NC

Weldon H Jordan, Jr, MD , Davis, CA

Thomas S. Kaluzynski, M.D , Bumsville, NC

G Wallace Kemodle, Jr., M D , Buriington, NC

Douglas P Kiel, M.D., Medfield. MA

Leigh S. Lehan, M.D.. Raleigh. NC

Robert E. Littleton. M.D.. Raleigh, NC

Jane E. Lysko, M.D., Asheville, NC

John R. Mangum, M.D., Sanford, NC
Saundra A. Maass-Robinson, M.D., East Point GA
Marcia J. McDutfie, M.D., Chariottesville, VA
Wan^n Winstow W. McMuny, M.D., Wilmington, NC
William H. Merwin, Jr., M.D., Knoxville, TN
Catherine H. MessKk, M.D., Winston-
Salem, NC

Charles B. Nemeroff, M.D., Ph.D., Atlanta,
GA

John Thomas Newton, M.D., Clinton, NC
Lany C. Nickens, M.D., Goldstxjro, NC
William 8. Olds, M.D., Roxboro, NC
Paul M. Partner, M.D. Atlanta, GA
Ruth M. Pari<er, M.D., Atlanta, GA
Peter L Pleasants, M.D., Providence, Rl
Lany B. Poe, M.D., Binghamton, NY
Nancy M. Reierson, M.D., Coconut Grove,
FL

Anne Marie A. Riether, M.D., Peachtree City, GA
Teresa A. Rummans, M.D., Rochester, MN
John W. Sanders III, M.D., Wilmington, NC
Timothy G. Saunders, M.D., Chariotte, NC
Thomas J. Seety, M.D., Summerfield, NC
Jane H. Sprague, M.D., Blacksburg, VA
George H. Steele, Jr., M.D., Merion Station, PA
Jeannette F Stein, M.D., Durham, NC
Ehwood E. Stone, Jr., M.D., Cedar Rapkis,
lA

William W. Stuck, M.D., Columbia, SC
Ronald M. Walters, M.D., Whiteville, NC
James D. Whinna, M.D., Monroe, NC
William Winkenwerder, Jr, M.D., Wellesley, MA
Warden L Woodard III, M.D., Chariotte, NC
Michelle H Wynn, M.D., Chariotte, NC

CL^SSOF1982
Number in Class: 146
Percent Donors: 23%

John C. Adams, M.D., Indian Trail, NC

Joseph I- Albright, Jr., M.D., Chartotte, NC

Mary John Baxley, M.D., Greensboro, NC
J. Lawrence Brady, Jr., M.D., Chariotte, NC
David W. Cash, M.D., Statesville, NC
Louisa E. Chapman, M.D., Atlanta, GA
Nancy C. Chescheir, M.D., Chapel Hill, NC
Reese H. Claris, M.D., Weston, FL
Rick J. Cornelia, M.D., Boone, NC
Cindy S. Dieringer, M.D., Camden, SC
Lawrence M. Fleishman, M.D., Chariotte, NC
Teny L Fon-est M.D., Goldsboro, NC
Charles J. Fulp, Jr., M.D., Atlanta, GA
Thomas W. Graham, M.D., CantxDro, NC
Jeffrey G. Hoggard, M.D., Greenville, NC
Sarah W Hudson, M.D., Elizabeth City, NC
Stephen M. Hux, M.D., Winston-Salem, NC
Tinnothy 0. Jenkins, M.D., Concord, NC
Thomas L Johnson, Jr, M.D., Culver City, CA
Angela Kendrick, M.D,, Aloha, OR
Bartiara A, King, M.D., Bakersville, NC
Marian S. KIrkman, M.D., Carmel, IN
Vincent J. Kopp, M.D., Chapel Hill, NC
Mary T Korytkowski, M.D., Pittsburgh, PA
James T Massagee, M.D., Greenslxiro, NC
Bonnie B. McCafferty, M.D., Englewood, CO
Howard D. McClamrock, M.D., Baltimore, MD
David W McMunry, M.D., Concord, NC
Linville M. Meadows, M.D., Jacksonville, FL

Anne G Tyson, M.D., Lakeland, FL

Eric D. Van Tassel, M.D., Asheville, NC

James G. Wall, M.D., Concord, NC

Kathryn L. Weise, M.D., Cleveland Heights,

OH

Stanley A. Wilkins, Jr., M.D., Raleigh, NC

CLASS OF 1983
Number in Class: 147
Percent Donors: 28%
DavM J. Ballard, M.D., Ph.D., Dallas, TX

Marsha F Berttxjlf, M.D., Jacksonville, FL

James A. Bryan III, M.D., Chapel Hill, NC

Aubrey D. Caltioun, M.D., Mooresville, NC

Donald W. Camnger, M.D., Robbinsville, NC

Vincent K. Cheek, M.D., Greenslwro, NC

Ralph S. Christy, Jr, M.D., Concord, NC

Douglas W. Claris M.D., Chapel Hill, NC

Ronald W. Cottle, M.D., Rorence, SC

Cristin B. Cullander, M.D., Eugene, OR

Thomas C. Darrell, M.D., Fuquay-Varina,

NC

Mary Anne Dooley M.D., Chapel Hill, NC

James L Everette, Jr, M.D., Dover, DE

Robert N. Headley, Jr., M.D., Lynchburg, VA

John M. Herion, M.D., Wilmington, NC

Cecilia G. Hipp, M.D., Chariotte, NC

Stephen W. Hipp, M.D., Charkitte, NC

Rebecca F Hopkins, M.D., Anderson, SC

Thomas T Hunter, M.D., Jacksonville, NC

Barbara E. Johnston, M.D., New Yoik, NY

James D. Ladd, M.D., Asheville, NC

Peter J. Larson, M.D., Oakland, CA

Bartara B. McPherson, M.D., Greensboro, NC

Margaret N. Moms, M.D., Asheville, NC

Jackie A. Newlin-Saleeby, M.D., Raleigh,

NC

C. Michael Nicks, M.D., Hickory, NC

Sally A. Nicks, M.D., Hickory, NC

James C. Ostxime, M.D., Greenstxiro, NC

Joan T Peny, M.D., Kinston, NC

Wanda M. Peterson, M.D., Winston-Salem, NC

Gary T Podgorski, M.D., Columbia, TN

Hermon W. Smith III, M.D., West Friendship, MD

Bartjara H. Smith, M.D., Greensboro, NC

Paula Y Smith, M.D., Gary, NC

Eugene R. Scares, M.D., Dover, NH

Paul B. Suh, M.D., Durham, NC

Deborah L. TUssing, M.D., Sevema Park,

MD

Mary C. Wasko, M.D., Pittsburgh, PA

John H. Williams, M.D., Raleigh, NC

Glenn A. Withrow, M.D., Chapel Hill, NC

Lawrence M. Wyner, M.D., Charieston, WV

CLASS OF 1984
Number in Class: 133
Percent Donors: 28%

James P Alexander Jr, M.D., Decatur, GA

Jay A. Anderson, M.D., Sumter. SC

Patricia F Culhane, M.D., Campbell, CA

W. Kent Davis, M.D., Raleigh, NC

Charies L. Ewell, Jr., M.D., New Albany, OH

Stephen E. Gitelman, M.D., San Francisco. CA

Margaret L Gulley M.D., San Antonio, TX

Ronakl R Hargrave, M.D., ML Pleasant, SC

James Can/er Hill, M.D., Gary, NC

Susan J. Joyner, M.D., Raleigh, NC

Robert F. Murray III, M.D., Pleasant Rklge,

Oscar Jet Webb, M.D., Menitt Island, FL

Michael J. Knight M.D., North Hampton, NH

Ml

Matthew L Whitted, M.D., Virginia Beach, VA

Rotjert R Linetjerger, M.D., Chapel Hill, NC

Albert J. Osbahr III, M.D., Waynesville, NC

Johnathan D. Williams, M.D., Gastonia, NC

Jo M. Marturano, M.D., Lexington, SC

Janice L. Rea, M.D., Lawrenceville, GA

Nicholas S. Zarzar, M.D., Hillsborough, NC

Brenda C. McClain, M.D., North Haven, CT

Joel E. Schnekler, M.D., Raleigh, NC

Robert W. MoMurray, Jr., M.D., Brandon, MS

Martin E. Sheline, M.D., Atlanta, GA

CLASS OF 1987

Jane H. Murray, M.D., Duriiam, NC

McCrae S. Smith, M.D., Greensboro, NC

Number in Class: 148

Howard W. Newell, Jr, M.D., Goldsboro, NC

Beverly G. Stigall, M.D., Greenville, SC

Percent Donors: 34%

Christopher C. Ng, M.D., Nashville, TIM

S. Patrick Stuart, Jr., M.D., Winston-Salem,

Linda R. Belhom, M.D., Chapel Hill, NC

R. Claiborne Noble, M.D., Raleigh, NC

NC

Thomas H. Belhom, M.D., Ph.D., Chapel Hill, NC

Douglas W. Peed, M,D., Chapel Hill, NC

Caria A. Sueta, M.D., Chapel Hill, NC

William S. Blau, M.D., Ph.D., Chapel Hill, NC

TTiomas M. Price, M.D., Greenville, SC

Claudia L. Thomas, M.D., Sands Point, NY

David W. Boone, M.D., Raleigh, NC

Ronald E. Pruitt, M.D., Nashville, TN

Dorothy E. TTiomas, M.D., Louisville, KY

Melissa W. Burch, M.D., Orono, ME

Alfred L. Rhyne III, M.D., Charlotte, NC

James A. Wainer, M.D., Raleigh, NC

Scott E. Campbell, M.D., Austin, TX

Richard G. Saleeby, Jr., M.D., Raleigh, NC

Bradley K. Weisner, M.D., Charkrtte, NC

Lisa A. Christman, M.D., Raleigh, NC

Robert A. Sammons, Jr., M.D., Grand Junction, CO

Randall W. Williams, M.D., Raleigh, NC

Gregor G. Cleveland, M.D., Ph.D.,

David L Sappenfield, M.D., Durtiam, NC

Shenie E. Zweig, M.D., Chapel Hill, NC

Timmonsville, SC

Paul W. Sasser, M.D., Eden, NC

David A. Coggins, M.D., Pennsylvania Fumace, PA

John M. Schoffstall, M.D., Glen Mills, PA

CLASS OF 1986

James B. Collawn, M.D., Raleigh, NC

Rebecca S. Socolar, M.D., Chapel Hill, NC

Number in Class: 144

Lochrane G. DavkJs, M.D., Greenville, SC

Thomas C. Spangler, M.D., Winston-Salem,

Percent Donors: 32%

1. Gordon Early, Jr., M.D., Spartanburg, SC

NC

Steven J. Baumaicker, M.D., Church Hill, TTM

Beverly H. Falls, M.D., High Point, NC

Sharon R. Stephenson, M.D., Cary, NC

M. Todd Brown, M.D., Charlotte, NC

Lee A. Furlong, M.D., Seal Rock, OR

Jean G. Taylor, M.D., Greensboro, NC

Mary B. Burgoyne, M.D., Easton, MD

Andrea N. Hass, M.D., North Palm Beach, FL

Paul E. Viser, M.D., Clinton, NC

Richard A.Burgoyne, M.D., Easton, MD

J. Franklin Hatchett, Jr., M.D.,

Robert A. Wainer, M.D., Greensboro, NC

Mary A. Callahan, M.D., New York, NY

Summerfiekl, NC

Robert E. Wiggins, Jr, M.D., Asheville, NC

Mary Beth A. Carter, M.D., Wilmington, NC

Rkshard H. Havunjian, M.D., Los Angeles,

Daniel W. Williams III, M.D., Lewisville, NC

Mkshael D. Carter, M.D., Wilmington, NC

CA

John W. Williams, Jr., M.D., San Antonio, TX

James W. Cheek, M.D., Jacksonville, FL

Albert R. Hinn, Jr, M.D., Chapel Hill, NC

Elizabeth T. Claric, M.D., Oak Park, IL

James P Hooten, Jr, M.D., Eton College, NC

CLASS OF 1985

William M. Clark, Jr., M.D., Oak Park, IL

Dennis N. Jacokes, M.D., Raleigh, NC

Number in Class: 152

Jennifer R Coursen, M.D., Seattle, WA

R. Lee Jobe, M.D., Raleigh, NC

Percent Donors: 30%

William F neet III, M.D., Brentwood, TTM

William W. King, M.D., Wilmington, NC

A. Elizabeth Allen, M.D., Winston-Salem, NC

Herbert Gaston Garrison III, M.D.,

David A. Klein, M.D., Chapel Hill, NC

S. Leonard Auman, Jr., M.D., Dallas, TX

Greenville, NC

Bret A. Kort, M.D., Colorado Springs, CO

Leslie A. Bunce, M.D., Chapel Hill, NC

Lynne Covington Garrison, M.D.,

Thomas E. Lawrence, M.D., Greensboro, NC

Joanne M. Cameron, M.D., Mattapoisett, MA

Greenville, NC

Catherine K. Lineberger, M.D., Chapel Hill, NC

Kathleen M. Clarke-Pearson, M.D.,

Elizabeth V. Getter, M.D., New York, NY

Julia 0. Lunsford, M.D., Raleigh, NC

Chapel Hill, NC

David C. Gotf, Jr, M.D., Winston-Salem, NC

Cary C. McDonald, M.D., Chapel Hill, NC

Laura L Crow, M.D., Greensboro, NC

Pamela G. Hanna, M.D., Comelius, NC

Teresa B. Mehrin, M.D., Mooresville, NC

Douglas S. Diekema, M.D., Kenmore, WA

Connie D. Han-ill, M.D., Indianapolis, IN

Douglas E. Mesler, M.D., Andover, MA

Douglas Shure Feltman, M.D., Coral Gables, FL

Kelvin C. Han-is, M.D., Gastonia, NC

Sherry L. Morris, M.D., Harrisonburg, VA

Kenneth E. Fen-ell, Jr, M.D., Charlotte, NC

Baice E. Herman, M.D., Salt Lake City, LfT

Lisle M. Natiell, M.D., Binningham, AL

Sheryl A. Gillikin, M.D., Fayetteville, NC

William D. Hoover, Jr, M.D., Concord, NC

Frances A. Owl-Smith, M.D., Farmington,

John H. Gilmore, Jr., M.D., Chapel Hill, NC

J. Curtis Jacobs, M.D., High Point, NC

NM

Charles A. Harper, Jr., M.D., Greensboro,

Rebecca S. Kennedy, M.D., Graham, NC

John M. Petitto, M.D., Gainesville, FL

NC

Patricia C. LaRocco, M.D., Fair Lawn, NJ

Virginia M. Pettito, M.D., Gainesville, FL

Charles S. Hayek, M.D., Shelby NC

Jonathan K. Levine, M.D., Charlotte, NC

Nancy W. Phifer, M.D., Buriington, NC

Brentley D. Jeffries, M.D., Asheville, NC

Sidney Mallentaum, M.D., Virginia Beach, VA

David B. Robinson, M.D., M.PH., Auke Bay AK

Margaret G. Johnson, M.D., Chapel Hill, NC

Leslie C. McKinney M.D., Raleigh, NC

Daniel M. Sappenfield, M.D., Charlotte, NC
Marc S. SchwartztDerg, M.D., Leesburg, FL

Peter M. Jordan, M.D., Greensboro, NC

Charles G. Miller, M.D., Boone, NC

Stuart H. Jordan, M.D., Fayetteville, NC

Michael R. Miller, M.D., Statesville, NC

Constance J. Sewell, M.D., Asheville, NC

David C. Joslin, M.D., Greensboro, NC

Lisa F Dejamette, M.D., Raleigh, NC

Ronald B. Shapiro, M.D., Austin, TX

Eric R. Kenny M.D., Lynchburg, VA

Anne D. Oakley M.D., Spokane, WA

David L. Sheppard, M.D., Gulf Breeze, FL

Theodore C. Kemer, Jr., M.D., Lewisville,

Steven R. Olson, M.D., Greensboro, NC

David J. Sheridan, M.D., Columbia, SC

NC

Rita Panoscha, M.D., Ardmore, PA

Robyn L. Stacy-Humphries, M.D.,

John A. Kirtdand, Jr., M.D., Charlotte, NC

David C. Pearce, M.D., Richmond, VA

Charkitte, NC

Mark H. Knelson, M.D., Durham, NC

John D. Reed, M.D., Greenville, NC

Brian S. Strauss, M.D., High Point, NC

Frank A. Luzzi, M.D., Torrington, CT

Mark C. Remington, M.D., Mercer Island,

William R. Sutton, M.D., Wilmington, NC

James E. Manning, M.D., Hillstxirough, NC

WA

Victoria B. Teague, M.D., Alpharetta, GA

Elizabeth S. McCuin, M.D., Roanoke, VA

Tobias Schifter, M.D., Tempe, AZ

Quang T Tran, M.D., Lynn Haven, FL

Gwenn Elizat)eth McLaughlin, M.D., Coral Gables,

C. W. Sofley Jr, M.D., Anderson, SC

Robert M. Walasin, M.D., Chapel Hill, NC

PL

Cathy Jo W. Swanson, M.D., Roanoke, VA

Jonathan J. Weiner, M.D., Durtiam, NC

Helen L Miller, M.D., New Haven, CT

Deborah D. Viglrone, M.D., Gulf Breeze, FL

Nancy H. Miller, M.D., Longmeadow, MA

Deborah T. Wadsworth, M.D., Des Peres,

CU\SSOF1988

Ten-ence D. Morton, Jr, M.D., Mooresville, NC

MO

Number in Class: 147

34

Albert R. Munn III, M.D., Raleigh, NC

L. Tyier Wadsworth III, M.D., Des Peres, MO

Percent Donors: 30%

C. Trent Blackman, M.D., Concord, NC
Jon R Brisley, M.D., Salem, VA

Maura L Campbell, MD., Murtreesboro, TN

J. Craig Charles, M.D., Winston-Salem, NC

Peter G. DalkJorf, M.D.. Greensboro, NC

Keitti A. Davis, M.D., San Diego, CA

Margie B. Eason, M.D., Martinsville, VA

Paul R. Eason, MD., Martinsville, VA

C. Gaelyn Garrett, M.D., Nashville, TN

Bartara K. Gavin, M.D., Boston, MA

Kirsten G. Girkins, M.D., Charlotte, NC

Hunter A. Hoover, M.D., Charlotte, NC

Sally S. Ingram, M.D., Chapel Hill, NC

Allison L Jacokes, M.D, Raleigh, NC

C. David Johnson, M.D., Blythew/ood, SC

Michael D. Johnson, M.D., GokJsboro, NC

Kathryn P. King, M.D., Carrtioro, NC

Hannah R. Kriginan, M.D., St Louis MO

Ritsu Kuno, M.D., Midlothian, VA

Jane M. Laco. M.D., Ptymouth MN

Michael E Lee, M.D., Virginia Beach, VA

Stuart J. Levin, M.D., Raleigh, NC

Thaddeus L McDonald III, M.D., Raleigh, NC

Catherine L Munson, MD., Fort Mill, SC

Philip J. tvlahser, Jr, M.D., Greensboro, t\IC

Charles E. Parke, M.D., Greenville, SC

Mahrad Paymani, M.D., Leesburg, FL

Marjorie D. Paymani, M.D., Leesburg, FL

Gary L Pellom, M.D., Durham, NC

John E. Peny III. M.D., Raleigh, NC

Gail Quackenbush, M.D., Leonia, NJ

Cecelia B. Ramsey M.D., Chartotte, NC

Jacquelyn L Redd, M.D., Silver Spring, MD

H. Kyle Rhodes, M.D., Wilmington, NC

Jeffrey E. Roller, M.D., Monganton, NC

Charies D. Scheil, M.D., Hickory, NC

James. M. Schmidt M.D., Chartotte, NC

Mary F Smith, M.D., Chapel Hill, NC

Daniel J. Stackhouse, M.D., Chartotte, NC

John D, Symanski, M.D., Chartotte, NC

Roger P Tart M.D., Mobile, AL

Spyro P Vulgaropulos, M.D., Gary, NC

Edward W. Whiteskles, M.D., Wilmington,

NC

Elliott F Williams, M.D., High Point NC

CLASS OF 1989
Number in Class: 142
Percent Donors: 20%

Paul E. Austin, M.D., Durtiam, NC
Kristin D. Baker, M.D., Concord, NC
Scott M. Baker, M.D., Concord, NC
Christopher Bultock, M.D., Alpena, Ml

Lisa K. Bori<e. M.D., Manetta, GA
Margaret F Campbell, M.D., Greenst»ro, NC
Shannon S Carson, M.D., Chapel Hill, NC
Brenda K. Cowell, M.D., Chartotte, NC
Daniel T Goulson, M.D., Lexington, KY
Michael Gnjenthal, M.D., Louisville, KY
Douglas B. Hansen, M.D.. Rock Hill. SC
Rosemary Jackson, MD. Bahama, NC
Patricia I- Jolie, M.D., Castleton, NY
Daniel M. Kaplan, M.D., Raleigh, NC
William H. Kelly, MD.. Fayetteville, NC
Charies G Lampley IV. MD,, Shelby, NC
Kenneth S. Maxwell, M.D., Winston-Salem,
NC

James M. McLean, M.D., Winston-Salem, NC
Jay B. Michael, M.D., High Point NC
William F McGuirt, Jr, M.D., Winston-Salem, NC
Christopher D. McKinney, M.D., Kingsport, TN
Gregory F Murphy M.D., Greenville, NC
Rotiert F Noel, Jr, M.D., Henderson, NC
Yolanda V Scariett M.D., Hillsborough, NC
Mary D. Shearin, M.D., Jamestown, NC
G. Bradley Shemll, M.D., Greensboro, NC
John H. Stephenson, M.D., Rosw/ell, GA
Jon P Woods, M.D., Madison, Wl
Wendell G. Yarbrough, M.D., Chapel Hill,
NC

CLASS OF 1990
Number in Class: 1 43
Percent Donors: 22%

Teresa T Anderson, M.D., Albuquerque, NM
Lori W. Balaban, M.D., Chariottesville, VA
John E. BarMey, M.D., Chartotte, NC

Elizabeth D. Bell, M.D., Chapel Hill, NC
Robert M. Bernstein, M.D., Seattle, WA
Cedric M. Bright M.D., Durham. NC
Victor M Caceres, M.D., Atlanta, GA
Martyn J. Cavallo, M.D., Nashville, TN
Sandra C. Clartt M.D., Chapel Hill, NC
Scott M. Cochrane, M.D., Amherst MA
Catherine L Cooper, M.D., Richmond, VA
C. James Cummings, M.D., Asheville, NC
Bany T Degregorio, M.D., Portland, OR
Jon R Donnelly, M.D., Cape Elizabeth, ME
Thomas E. Edwards, Jr, M.D., Atlanta, GA
Rotiert R. Ehinger, M.D., Greensboro, NC
Amy S. Ende, M.D., Marion, NC
John W. Entwistle III, M.D., Lafayette Hill, PA
Russell D. Hall, M.D., Greenwood, SC
Susan J. Hardesty, M.D., Mount Pleasant SC
Louise F. Homey, M.D., Atlanta, GA
Stacey N. Ibrahim, M.D., Ashevilto, NC
Dominic A. Jaeger, M.D., Burtington, VT
Leigh H. Jones, M.D., Greensboro, NC
John H, Krege, M.D., Greenstxiro, NC
Philip C. Lackey, M.D., Chartotte, NC
Han-ison A. Latimer, M.D., Kinston, NC
Lori B. Lilley, M.D., Raleigh, NC
Lianne D, McKhann, M.D., Bronxville, NY
Angela R, Scott M.D., Salt Lake City, LH"
Eugenia B. Smith, M.D., Chapel Hill, NC
John H. Wood, M.D, Chapel Hill, NC

aASSOF1991
Number in Class: 146
Percent Donors: 27%

Came D, Alspaugh, M.D., Momsville. NC
Katrina H. Avery, M.D., Durtiam, NC

Mack N. Barnes III, MD., Birmingham, AL
N. Elaine BrosMe, M.D., Satom, OR

Elizabeth D, Brown, M.D., SummertiekJ, NC

Unda H. Butler, M.D., Raleigh, NC

Thomas R, Coleman, M.D., Lutz, FL

Megan M. Davies, M.D., Decatur, GA

Amy C, Degnim, M.D., Leeds, MA

Jane E. Drenkhahn, M.D., Salisbury, NC

C Neill Epperson, M D.. North Haven. CT

Cathenne M Gordon, M.D., Wellesley MA

Partyn T Hatch, M.D,, Ormond Beach, FL

Robert S. Hatch, M.D., Omiond Beach, FL

Leon W. Hemdon, Jr, M.D., Hillsborough, NC

Drew A. Jones, M.D., GreenslMro, NC

Uurie 0. Jordan, M.D., Smithfield, NC

W. Evans Kemp, Jr., M.D., Nashvilto, TN

Hetone R Keyzer^Pollard, M.D., Gastonia,

NC

Michael J. Lucas, M.D., High Point NC

Scott R. McDuffie, M.D., Sumter, SC

Jobe C. Metts III, M.D., Mount Ptoasant, SC

Julien L Naytor M.D., Anchorage, AK

Bryan R. Neuwirth, M.D.. Hickory, NC

Linda M. Nicholas, M.D., Chapel Hill, NC

Vincent C. Phillips, M.D., Engtowood, OH

Rtohard J. Pollard, M.D., Gastonia, NC

Amy J. Robbins, M.D., Chartotte, NC

Danny Silver, M.D., Raleigh, NC

Michael F Soboeiro, M.D., Rnehurst NC

Anil K. Sood, M.D., Coratville, lA

Todd F Tanner, M.D., GokJslsoro, f\IC

Richard L Toothman, M.D., Canollton, GA

Gilbert R. Upchurch, Jr, M.D., Ann Arbor, Ml

Joseph B. Webster, M.D., Greenville, NC

Frederick M. Weeks, M.D., Vero Beach, FL

Margaret W. Weeks, M.D., Vero Beach, FL

Angela F Whitted, M.D., Virginia Beach, VA

Patrick A. Wilson, M.D., Wilmington, DE

Edward H. Wrenn, M.D., Pittsburgh, PA

CU\SSOF1992
Numtier in Class: 146
Percent Donors: 21%

Jorge A. Allende, Jr., M.D., Fort Collins, CO
Mary M. Bledsoe Felkner, M.D., Charlotte, NC
J. Wesley Boyd, M.D., Northampton, MA
Lisa A. Brone, M.D., Boulder CO
Nancy C. Clayton, M.D., Chapel Hill, NC
* Gerald E. Cooley M.D., Chartotte, NC
Billie F Cosgrove, M.D., Wilmington, NC
Christopher C. Cosgrove, M.D., Wilmington, NC
John F. Ende, M.D., Marion, NC
Margaret F Farmer, M.D., Johnson City, TM
Mary J. Forbes, M.D., Raleigh, NC
Cari J. Gassmann, M.D., Scottsdale, AZ
Andy C. Kiser, M.D., Whispering Pines, NC
Victoria D. Lackey M.D., Chartotte, NC
Robert W. Larkin, Jr, M.D., Lancaster, PA
Susan R. Marcinkus, M.D., Luthen/ille, MD
Jennifer E. Moore, M.D., Greenbrier, TN
' Walter S. Moms III, M.D., Southem Pines, NC
Martin T. November, M.D., Cambridge, MA
David M. Guillen, M.D., Gainesville, FL
Chinda H. Roach Costello, M.D., Seattle, WA
J. Cullen Ruff, M.D., Ariington, VA
Randolph P Sellers, M.D., Chapel Hill, NC
Scott V Smith, M.D., Apex, NC
Anjali M. Sues. M.D., Raleigh. NC
Thor 0. Svendsen, M.D., Chartotte. NC
Stephen L Tilley M.D., Chapel Hill, NC
Rita E Treanor-Plemmons, M.D,. Erwin, TN
Bradford T Winslow, M.D., Denver CO
Lisa C. Winslow. M.D., Denver, CO
Karen S Wood, M.D., Pinehurst NC

CLASS OF 1993
Number in Class: 134
Percent Donors: 22%

Aleta A. Bonrud, M.D., Rochester MN

John S. Chase, M.D., bwa City lA

Christopher D. Ingram, M.D., Durham, NC

Leigh G. Cicci, M.D., New Orieans, LA

William L Craig III, M.D., Raleigh, NC

* Richard H. Jones, M.D., Patuxent River, MD

Elizabeth C. Claris, M.D., Portland, OR

Carolyn J. Dalldorf, M.D., Charlottesville, VA

Nicklas B. Oldenburg, M.D., Cambridge, MA

J. Brian Clari<, M.D., Durtiam, NC

Cathy A. Donovan, M.D., Onamia, MN

■ Monica L Recyk, M.D., Canton, MA

Michael Todd Cross, M.D., Bimiingham, AL

Patrick L Fry, M.D., Mooresville, NC

Laura M. Robert, M.D., Lynchburg, VA

Sarita Kumar Cross, M.D., Birmingham, AL

* S. Lynn Gardner, M.D., Stone Mountain, GA

Elizabeth F Rostan, M.D., Chariotte, NC

Nicole M. D'Andrea, M.D., Morehead CiW, NC

J. Judd Green, Jr, M.D., Jamestown, NC

Wesley G. Schooler, M.D., Durham, NC

Canrie A. Dow-Smith, M.D., Peariand, TX

Raymond C. Hausch, M.D., Hermantown, MN

Susan K. Seo, M.D., New Yori<, NY

Mari< T Dransfield, M.D., Bimiingham, AL

Lauren R Johnson, M.D., Chapel Hill, NC

Carol G. Shores, M.D., Chapel Hill, NC

Janet R. Encamacion, M.D., Springfield, MO

C. Anthony Kim, M.D., Puyallup, WA

Dana L Simpson, M.D., Charieston, SC

Eric D. Ervin, M.D., Henderson, KY

Laura S. Lenholt, M.D., Naples, FL

Jawal Suleman, M.D., Columbia, SC

Thomas W Gansman, M.D., Indianapolis, IN

David T. May, M.D., Asheville, NC

H. Clayton Thomason III, M.D., Gastonia, NC

Cathryn A. Geary, M.D., Cincinnati, OH

Lisa L May, M.D., Asheville, NC

Deidra E. Woods, M.D., Washington, DC

Bradley C. Gehrs, M.D., Birmingham, AL

Eugene H. Maynard, Jr, M.D., Smithfield, NC

Chandra S. Ghosh, M.D., Atlanta, GA

Richelle L McDaniel, M.D., Macon, GA

CLASS OF 1996

Maura L Hamrick, M.D., Literty, NC

Teressa Y. McKoy M.D., Charlotte, NC

Number in Class: 140

Heather M. Henderson, M.D., Lexington, KY

John D. Phipps, M.D., Winston-Salem, NC

Percent Donors: 25%

Richard W. Hudspeth, M.D., Salt Lake City, LfT

* John B. Recyk, M.D., Canton, MA

Mark G. Amaya, M.D., Mableton, GA

Srikant B. Iyer, M.D., Cincinnati, OH

Lawrence M. Raines III. M.D., Chapel Hill, NC

Sharon C. Amaya, M.D., Mableton, GA

John P Hunt M.D., Brighton, MA

Ellison L Smith, Jr, M.D., Asheville, NC

Wendy S. Amiore Edds, M.D., Chapel Hill, NC

Paul H. Kartheiser, M.D., Durtiam, NC

* Holly A. Stevens, M.D., Charlotte, NC

Clinton K. Atkinson, Jr, M.D., Greenville, NC

Andrew L. Katz, M.D., Durtiam, NC

Melinda C. Taylor, M.D., Raleigh, NC

Katherine E. Barett, M.D., Raleigh, NC

Davm E. Kleinman, M.D., Cantwro, NC

Charles B. league, M.D., Columbus, GA

David K. Becker M.D., Chapel Hill, NC

Jennifer S. KlenzaK M.D., Cumberiand Foreside,

* Theodore T Thompson, M.D., Abingdon, VA

Brian R Benfield, M.D., Shelby, NC

ME

Brian R. Webster, M.D., Wilmington, NC

Andrea C. Best, M.D., Santa Monica, CA

Jerome R Lee, M.D., Haleiwa, HI

David A. Wells, M.D., Asheville, NC

Sara B. Beyer, M.D., Matthews, NC

Kathryn A. Lee, M.D., Denver, CO

William R. Westerkam, M.D., Columbia, SC

Michael Joseph Casey M.D., Winston-Salem, NC

Nancy L Linscott, M.D., Salem, OR

Kir1< L Woosley M.D., Charlotte, NC

Lonaine D. Comwell, M.D., Carrtxjro, NC

Erica A. Lyndrup, M.D., New Haven, CT

Uura A. Gulp, M.D., Chapel Hill, NC

Donna B. McGee, M.D., Horse Shoe, NC

CLASS OF 1994

Cory A. Dunnick, M.D., Nashville, TM

Dean S. Mon-ell, M.D., Brookfield, Wl

Number in Class: 140

Douglas K. Graham, M.D., Highlands Ranch, CO

Krista S. Monis, M.D., Birmingham, AL

Percent Donors: 1 7%

Brian E. Grogg, M.D., Rochester, MN

T. Christopher Monis, M.D., Birmingham, AL ,

Kurt C. Bachmann, M.D., Bimningham, AL

Julie A. Haizlip, M.D., Salt Lake City, LfT

Jeffrey S. Moyer, M.D., Ann Artx)r, Ml

Laura H. Bachmann, M.D., Bimiingham, AL

Shannon G. Hamrick, M.D., San Francisco, CA

* Julia K. Nelson, M.D., Durtiam, NC

David A. Bartholomew, M.D., Chapel Hill, NC

Ann E. Hiott, M.D., Chapel Hill, NC

Brian S. O'Kelley M.D., Gainesville, FL '

Jane H. Brice, M.D., Chapel Hill, NC

Scott M. Klenzak, M.D., Cumberland Foreside, ME

John C. Partner, M.D., Lexington, KY

Marlene S. Calderon, M.D., Ann Artxir, Ml

E. Allen Liles, Jr, M.D., Durinam, NC

Sarah B. Philp, M.D., Seattle, WA

Jennifer E. Charlton, M.D., Lynchburg, VA

Michael H. Lowry, M.D., Pine Knoll Shores, NC

Jennifer E. Rhodes-Kropf, M.D., New Yori<, NY

Peter T Chu, M.D., Fletcher, NC

Daniel F Maher, M.D., San Diego, CA

Austin S. Rose, M.D., Chapel Hill, NC

Sujata V Ghate, M.D., Greensboro, NC

John E. Milko, M.D., Myrtle Beach, SC

T Christopher Sanchez, M.D., Columbia, MO

Kathleen G. Hill. M.D., Takoma Park, MD

Tracey E. O'Connell, M.D., Durtiam, NC

Jeffrey D. Smith, M.D., Ann Artjor, Ml

Jeffrey C. Johnson, M.D., Raleigh, NC

Anne G. Pinto, M.D., Newton, MA

Vincent C. Smith, M.D., Peariand, TX

Laura H. Lee, M.D., Gary, NC

David N. Quinn, M.D., Columbus, OH

Anne H. Stephens, M.D., Durtiam, NC

Peter H. Lee, M.D., Cary, NC

Virgil C. Reid III, M.D., Chicago IL

John R. Stephens, M.D., Durtiam, NC

Roy S. Lewis, M.D., Houston, TX

Kathy W. Richardson, M.D., Oak Ridge, NC

Amy M. Ursano, M.D., Durtiam, NC

Melissa M. Lutz. M.D., Chapel Hill, NC

Lisa M. Roberts, M.D., Kinston, PA

Julie C. VerchicK M.D., Rnehurst, NC

John L Matthews, M.D., Durham, NC

Tena L. Rosser, M.D., Washington, DC

Ralph N. Vick, M.D., Chapel Hill, NC

J. Whitman Mims, M.D., Winston-Salem, NC

Jeffry R Simko, M.D., Ph.D., Boston, MA

Deepak R Vivekananthan, M.D., Shaker Height, OH

Jacqueline H. Mims, M.D., Winston-Salem, NC

William T Smith IV, M.D., Durtiam, NC

Lauren E. Wagner M.D., Chicago, IL

Carolyn R Misick, M.D., Springfield, OH

Alan W Story, M.D., Newton, NC

Melanie R Walker, M.D., Cincinnati, OH

Julia E. Norem-Coker, M.D., Fayetteville, NC

Carlos A. Vargas, M.D., Franklin, NC

* lllya L. Wilkerson, M.D., Greensboro, NC

Jose L Plaza, M.D., Charlotte, NC

David G. Whaley, Jr, M.D., Sumter, SC

Christopher R. Williams, M.D., Birmingham, AL

John W. Rusher, M.D., Raleigh, NC

Laura Clark Windham, M.D., Durtiam, NC

H. Ian Savage, M.D., Takoma ParK MD

CLASS OF 1997

Nitin R Shenoy, M.D., Hickory, NC

Number in Class: 157

CLASS OF 1998

Teny S. Strand, M.D., Greensboro, NC

Percent Donors: 40%

Number in Class: 131

Henry C. Baggett III, M.D., Anchorage, AK

Percent Donors: 39%

CLASS OF 1995

Michael L. Batten, M.D., Philadelphia, PA

John G. Alley, Jr, M.D., CarrtMro, NC

Number in Class: 163

Marsha W. Blount, M.D., LaJolla, CA

D. Michael Amistrong, M.D. , Charlottesville, VA

Percent Donors: 13%

Benjamin C. Brieger, M.D., Austin, TX

Christopher W. Baird, M.D., Pittsburg, PA

Helen B. Adams, M.D., North Branford, CT

George M. Brinson, M.D., Chapel Hill, NC

Elizabeth R. Bates, M.D., Oakland, CA

Paul H. Ijowman, M.D. , Augusta, GA

Debbie Ann Brown, M.D., Southfield, Ml

Michelle W. Beckham, M.D., Concord, NC

Christina L. Catlett. M.D., Ellicott City, MD

Richard C. Bumgardner, M.D., Wrightsville Beach,

Dalliah M. Black, M.D., Hillsborough, NC

Michele R. Casey M.D., Winston-Salem, NC

NC

Carol A. Borack, M.D., Rochester NY

Elizabeth C. Deterding, M.D., Summerfield, NC

Brett H. Cannon, M.D., Atlanta, GA

Stephen D. Brown, Jr., M.D., South

S. Bryan Durham, M.D., Wilmington, NC

Mari< D. Charison, M.D., Chapel Hill, NC

Burlington, VT

Richard Ryan Gessner, M.D., Charleston. SC

Steven V Chiavetta III, M.D., Rochester, MN

Natalie G. Cobum, M.D., Providence, Rl

Sarah Young Gessner, MD., Charleston, SC

Kathy N. Chism, M.D., Knoxville, TN

Alan Cook, M.D., Durtiam, NC

Christopher C. Coperhaver, M.D., Rochester, NY
Mary S. Crowder, M.D., Greenville, NC
Farr A. Curiin, M.D., Chicago, IL
Joseph G. Degenhanj, M.D., Lancaster, PA
Jason E. DeVente, M.D., Greenville, NC
William F Duriand, Jr., M.D., Maple Bluff, Wl
Amy D. Fairchikj, M.D., Chapel Hill, NC
Jonattian E. Rscher M.D., Cantioro, NC
Maxwell E. Rsher, M.D., Nashville, TM
Karolyn Forties, M.D,, Ann ArtxDr, Ml
• Angela B. Gantt-Holliday M.D., Dublin, OH
Nichole D. Grier, M.D., Chapel Hill, NC
Karen L Grogg, M.D., Rochester, MN
Chad Gunnlaugsson, M.D., Ypsilanti, Ml
Retjeccah A. Hoffman, M.D.. Pittsburgh, PA
Travis C. Honeycutt M.D., Norfolk, VA
Traci E Irwin, M.D., Chapel Hill, NC
Joseph T, Jenkins, M.D., Chapel Hill, NC
Charles N, Landen, M.D., Charieston, SC
Miriam W. Undrooth. M.D., Norlhfield, IL
Robert C. Miller, M.D., Wexford, PA
SiolDhan O'Conner, M.D., Louisville, KY
Rotiert S. Pari^ M.D., San Francisco, CA
Stephen J. Phillips, M.D., Baltimore, MD
William G. Pittman III, M.D., San Francisco, CA
Caroline C. Prochnau, M.D., AshetX)ro, NC
Maria H, Rothchild, M.D., Saint Louis, MO
Brian Shelley, M.D., Albuquerque, NM
William M. Shentxl, M.D., Augusta, GA
Mona A. Sinno, M.D., North Las Vegas, NV
Sheila D. Smith, M.D., Richmond, CA
Thomas E. Stephens, M.D., Asheville, NC
William H. Sturgill, M.D., Jacksonville, NC
Andrew J. Taytor, M.D, Wrightsville Beach, NC
Stephan D. Tfiiede, M.D., Chapel Hill. NC
Micfiael M. Walger, M.D., Loma Linda, CA
John W. Warner, M.D., Falls Church, VA
Alexandra T Whoriskey M.D., Larchmont NY
Paul L Winslow III, M.D.. Durham, NC
Rotjyn K. Zanard, M.D., Greenstxjro, NC
Adam J Zolotor, M.D,, Chapel Hill, NC

CLASS OF 1999
Number in Class: 118
Percent Donors: 39%

James M. Adams, M.D., Santa Monica, CA
Victor C. Archie. M.D.. Thousand Oaks, CA
Erin L Brackbill, M.D., Chicago, IL
Stephen P Brackbill, M.D., Chicago, IL
Daniel W. Bradford, M.D., Chapel Hill, NC
H. Scott Cameron II, M.D., Baltimore, MD
Nicole Chaisson, M.D., Saint Paul, MN
John B, Chiavetta, M.D,. Rochester, MN
Ellen C. Collett M.D., Monganton, NC
Jason D Conway, M.D.. Charlottesville. VA
Leigh M. Dodson, M.D,, Jeffersonville. IN
Stanley F Dover. M.D , Winston-Salem, NC
Robert A DuBose, M.D., Seattie, WA
Carrie L Dul, M.D., Portland, OR
S Sheppard Dunlevie, Jr, M.D,, Charlotte. NC
Michelle E. Elisburg, M.D., Kew Gardens, NY
Byron K. Evans, M.D.. Brooklyn, NY
William L Fan, M.D., Durtiam, NC
Lisa A. Flora. M.D., New Castle, DE
Cynthia L Gay M.D., Nashville, TN
Robert G. Goodrich, M.D., Chapel Hill, NC
Lisa J. Harrington, M.D., Providence, Rl
Angela L Helder, MD., Chapel Hill, NC

T Ryan Heider. M.D., Chapel Hill, NC

Claire E. Holland, M.D.. Albequerque, NM

Maija Holsti, M.D., Chapel Hill, NC

Winny W. L Hung, M.D., Providence Rl

Yewande J. Johnson, M.D., Birmingham, AL

John S. Kang, M.D., Cantxjro, NC

Thomas F Laney Jr, M.D., Boiling Springs, NC

Kevin J. Logel, MD., Salt Uke City, LfT

G. Marcus Lowry, M.D., Winston-Salem, NC

Allison S. McBride, M.D., Nashville, TM

Marion M. McCrary, M,D., Durtiam, NC

Ben M. Meares, Jr, M.D., Taylors, SC

Melinda Menezes-Sanchez, M.D., Kapaa, HI

Brian H, Mullis, M.D., Durtiam, NC

Michael C. Noone, M.D., Mount Pleasant, SC

Tara M. Rice, M.D., Durtiam, NC

Elizabeth C. Roede, M.D., New Yori<, NY

Latonya B. Thompson, M.D., AlalDaster, AL

Julia W. Tsang, M.D., Chapel Hill, NC

A. Elizabeth Underwood, M.D., Salt Lake City, LTT

Eric S. Winer, M.D., Newton, MA

Mark L Wood. M.D. Chapel Hill, NC

John J. Young, Jr, M.D.. Chapel Hill, NC

CLASS OF 2000
Number in Class: 130
Percent Donors: 21%

James R. Alexander, M.D., Chariotte, NC
Megan H. Bair-MenitL M.D., Media, PA
Myriam F Bauer, M.D., Durham, NC
Anne W. Beaven, M.D., Chapel Hill, NC
Seth M. Cohen. M.D.. Nashville, TTM
Brian W. Downs, M.D., Durtiam, NC
Cescili A. Drake, M.D., Durtiam, NC
William T Durtiam, M.D., Birmingham. AL
Sonja T France. M.D.. Gainesville. FL
Harvey J, Hamrick. Jr, M.D.. San Francisco. CA
Marie N. Hardy. M.D., Carttxjro, NC
Carolyn L Hess, M.D., Chariotte, NC
Shawn B. Hocker, M.D., Chapel Hill, NC

• Caroline M. Hoke, M.D., Durtiam, NC
Jennifer A. Hooker, M.D., Carrtxiro, NC
Skylar E. Kalady, M.D., Durtiam, NC
Dennis J. Kubinski, M.D., Winston-Salem, NC
Kevin M. Lee, M.D., Hillsborough. NC
Madelena M. Martin, M.D., Highland, CA
Peter H. McHugh, M.D., Memphis, TM
Jeffrey S, Mueller, M.D., Pittsburgh, PA
Michael K. Nevmnan, M.D., Richmond. VA
Wendy G. Owen, M.D., Durtiam, NC

Lisa Rahangdale, M.D,, Chicago, IL

* Heather N, Robertson White, M.D., Chariotte. NC
Douglas D. Rockacy. M.D.. Pittsburgh. PA
Elizabeth A. Steele. M.D., Menio Park, CA

CU\SS OF 2001
Number in Class: 111
Percent Donors: 9%

Faera L Byerly, M.D,. Ariington, MA
Donna R Childress, M.D , Salisbury, NC
Victoria L Cressman, M.D , Bronxville, NY
Stuart M, Hardy, M.D,. Canrboro, NC
Michael A, Houston. M.D., Statesville, NC
S. David Hsu, M.D.. Ph.D., Durtiam, NC
Brian C. Jensen, M.D., Boston, MA
Jonathon J, Juliano, M.D., Chapel Hill, NC
Michaux R, Kilpatrick, M.D., Ph D., Durtiam. NC
Ari Urakubo, MX).. El Granada. CA

Ariel S. Vincent. M.D., Santa Bartjara, CA

CLASS OF 2002
Brian L Cohen, Durtiam, NC
* denotes Loyalty Fund Junior Associate

ALLIED HEALTH SCIENCES GRADUATES

Duane S. Anderson, Jr, Staunton, VA
Denise G. Arnold, Jacksonville Beach, FL
Elizabeth A. Bridges,, Atlanta, GA
Laura L Chapman,, Birmingham, AL
Jane M. Cobum,, Durtiam, NC
Sharyn H. Davies, Little Rock. AR
Jason M. Denton. Concord, NC
Debra R. Emst West Bloomfield, Ml
Heather A. Ganabrant,, Raleigh, NC
Retiecca A. Hanson, Portland, OR
Leslie C. Hawley Corpus Christi, TX
Claire G. Herting, Ortando, FL
Geraldine K. Highsmith, Raleigh, NC
Todd B. Hoff, Newton, NC
Erin M. Ingram, New Yori^ NY
Tricia E. Jaworski, Clayton, NC
Emily Z. Johnson. Rndlay OH
Nobey C. Jones, Kalamazoo, Ml
Jeffrey E. Kingan, Chapel Hill, NC
Kimberly B. Klug. Menomonee Falls, Wl
Jeffrey L Krafft Waxhaw, NC
Esther G. Lawley Fayette, AL
Scott C. Livingston, Erie, PA
Susan G. Maness, Greenstwro, NC
Chiquetta S. Mangum, Durtiam, NC
Sheila R. McMahon, Raleigh, NC
Mary-Frances Menwin, Knoxville, TN
Mari< Miele M.D., Gastonia, NC
Kristi A. Morse, Duluth, MN
Virginia M. Nieland, Charieston, SC
Kelli H. O'Neil, Newton, NC
Jennifer P Pate, Wilmington, NC
Mary M. Rendleman, Raleigh. NC
Janet T Robbins, Lewisville, NC
Marjorie E. Robinson. Ocala, FL
Diosdado G, Salaveria, Birmingham, AL
Nancy Margaret Saleeby Chapel Hill, NC
Jane C. Schroeder, Chapel Hill, NC
Andrew M. Sever, Doraville, GA
Patricia S. Sikes, Durtiam, NC
Katharine C. Simmons, Acton, MA
Diane E. Travis, Cincinnati, OH
Laura E. Ward, Cockeysville, MD
Shelby T Weisberg, Setauket. NY

BASIC SCIENCES GRADUATES

Rotiert T Aartius, Hillsborough, NC
Michael Ackerman, PhD , Bethesda, MD
Nils B. Adey Ph.D., Salt Lake City, LfT
Alison J. Alaimo, Midland, Ml
Caroline H Aland, Stevensville, MD
Margaret C Anderson, Chatanooga, TN
Eric T Baldwin, Ph.D., Kalamazoo, Ml
Richard A, Banks, Ph.D., Nevirport News, VA
Nancy N. Belding, Hillsborough, NC
Pamela M. Bimlx), Asheboro, NC
William F Bird, Durtiam, NC
Debra D Bkxxn, PhD , Sun Prarie. Wl
Timothy J Boiling, Wilmington, DE
Joan R Boone, Efland, NC m

37

Carl D. Bortner, Pti.D, Durtiam, NC

Aziz A. Boxwala, Boston, MA

Susanne M. Breckenridge, Stafford, VA

Sharon M. Brown, Marion, SC

Suzanne C. Bullocl^, Blowing Rock, NC

BartMra A. Burkhart, Pti.D., Apex, NC

Margot G. Butchart, Ormond Beach, FL

Ronald K. Charlton, Ph.D., Jacksonville, FL

Nancy R. Clendenon, Ph.D., Arapahoe, NC

Maria M. Coble, East Bmnswick, NJ

G. Ray Collins, Rocky Mount, NC

Laurie B. Connell, Ph.D., Seattle, WA

Timothy W. Con^igan, Charlotte, NC

Bartara F Couch, Durtiam, NC

Debra K. Cowan, Chapel Hill, NC

Victoria Z. Coward, Jacksonville, FL

Merie M. Crawford, Hummelstown, PA

Bobbi P Crummett, Chapel Hill, NC

Michelle L. Cunningham, Ph.D., Chapel Hill, NC

Kimberiy C. Daeke, Gary, NC

Dorothy L Daley, Wilmington DE

Lloyd A. Dethloff, Ph.D., Ann Artwr Ml

Anne B. Deutsch, Greenstxiro, NC

Lori Ann Dostal, Ph.D., Brighton Ml

Stephen Alan Dovenitz, Durtiam, NC

Martha W. Easley, Amelia Island, FL

Andrea D. Eckhart, Ph.D., Durtiam, NC

Rorine D. Everton, Greenstxiro, NC

Elissa J. Falkenstein, Alpharetta, GA

Belinda K. Fetner, Raleigh, NC

James C. W. Finley, Ph.D., Cleveland OH

Katherine L. Fries, Ph.D., Atlanta, GA

George J. Galasso, Ph.D., Rockville, MD

Parul K. Galloway, Chapel Hill, NC

Perry A. Geneva, Ph.D., Chapel Hill, NC

Delores J. Grant, Ph.D., Chapel Hill, NC

Robert R Gmninger, Chapel Hill, NC

Harnett L Hargis, Durtiam, NC

Heidi A. Hari<ins, Ph.D., Chapel Hill, NC

Willard G. HanBlson, Jr, Ph.D., Pittsboro, NC

Janet L. Harrill, Forest City, NC

Marcia W. HertDert Virginia Beach, VA

Nancy M. Higgins, Moncure, NC

Edna D. Hodges, Washington, NC

Mou-Tuan Huang, Ph.D., Englewood Cliffs, NJ

Anne C. Huff, Ph.D., Collegeville, PA

Marthatou Hunter, Brevard, NC

Eric A. Jackson, Hartford, CT

Jane E. Jordan, The Woodlands, TX

Scott E. Justus. Chapel Hill, NC

Stephanie L Khan, Cleveland, OH

Deborah W. King, Bremerton, WA

Susan A. Klemm, Chariotte, NC

Stephen 8. Knisley, Ph.D., Bimningham, AL

Carolyn J. Koch, Chapel Hill, NC

Elizatjeth H. Kopiwoda, Knoxville, TN

Lauree M. Knjyer, Southern Pines, NC

Margaret W. LaManna, Shaker Heights, OH

Teresa C. Leavens, Ph.D., Cary, NC

Constance F Lefler, Ph.D., Fort Worth, TX

Robert A. Lerch, Ph.D., Spring Valley, NY

Chunnan Liu, Ph.D., Abington, PA

Carol J. Ludwig, HillstxDrough, NC

Amy H. Lumsden, Ariington Heights IL

Frankie W. Lyons, Salisbury, NC

Mart Manchester, Ph.D., San Diego, CA

Mary L Marazita, Ph.D., Wexford, RA

Melissa Maret, Ph.D., Yardley, PA

Sally A. Maser, Philadelphia, PA

Arthur Maslow, Tacoma, WA

Sheryl Venable Massey, Pendleton, SC

Bruce E. Miller, Ph.D., Collegeville, PA

Margaret B. Moore, Sanfonj, NC

Susan H. Moore, Raleigh, NC

Lynda S. Morrison, Henderson, KY

Virginia W. Morton, Houston, TX

Michelle M. Nicolle, Ph.D., Jacksonville, FL

Paula M. Oliver, Denver, CO

Wendy P Osheroff, Durtiam, NC

Ann W. Peace, Teppahannock, VA

Christopher A. Pennell, Ph.D., Mendota Heights, MN

Cynthia E. Phillips, Marietta, GA

Diane L Phillips, Auburn, CA

Nell N. Pressley, Lilbum, GA

Joyce J. Prillaman, Mocksville, NC

Emily A. Rantzos, Asheville, NC

Maijorie S. Read, Ph.D., Durtiam, NC

Pamela L Reading, Ph.D., Chapel Hill, NC

Julie Reuter, Ph.D., Durtiam, NC

Constance D. Rothermel, Ph.D., Essex Falls, NJ

Drusilla L Scott, Ph.D., Ann Artx)r, Ml

Patricia Scronce, Woodbridge, VA

RetDecca A. Shirty Ph.D., Malvern, PA

Caroline W. Silver, Apex, NC

Sheni C. Sindel, Mobile, AL

Dolores E. Sink, Mooresville, NC

Jennifer V Smith, Ph.D., West Chester, PA

Phillip G. Smith, Durtnam, NC

Retjecca A. Smith, Greenstwro, NC

Susan J. Smith, Newton, NC

Linda S. Soles, Hillsborough, NC

Milbrey C. Stames, Ph.D., Chapel Hill, NC

Sanford L. Steelman, Ph.D., Hickory, NC

Pamela Perry Stubbs, Fallbrook, CA

John T Swinson, Alexandria, VA

Faye C. Swofford, Elm City, NC

Ann W. Thomson, Asheville, NC

Tsong-Tseh Tsay, Ph.D., Orange, CA

Irene M. Vandiviere, Lancaster, KY

Charles J. Viviano, Ph.D., Beacon Falls, CT

Martha M. Voipe, Rochester, NY

Michael D. Waters, Ph.D., Chapel Hill, NC

Elizatieth C. Wilkinson, Youngsville, NC

Camille B. Williams, Milford, MA

Helen R. Williams, Tampa, FL

Paula K. Williams, Chicago, IL

Jennifer L. Womack, Durtiam, NC

Unda Lee Woodard, Chapel Hill, NC

Donna L. Wright, Ph.D., Wichita Falls, TX

Yuxin Yin, Ph.D., Tenafly, NJ

Dorothy C. Young, Ph.D., Collegeville, PA

Huabing Yuan, Chesterfield, MO

Franca R. Zaretzky, Ph.D., Chariottesville, VA

FACULTY

John Joseph Aluise, M.D., Chapel Hill, NC

Lany W. Arnold, M.D., Snow Camp, NC
Stephen R. Aylward, Ph.D., Chapel Hill, NC
Walter R. Benson, M.D., Chapel Hill, NC
Stuart O. Bondurant, Jr., M.D., Chapel Hill,
NC

Gary D. Bos, M.D., Chapel Hill, NC
IMalson A. Bowes, Jr., MJ)^ Chapel Hill,
NC

H. Robert Brashear, Jr., M.D., Chapel Hill,
NC

R. Alan Briggaman, M.D., Chapel Hill, HC
James A, Bryan II, M.D., Chapel Hill, NC
John B. Base, M.D^ PhJ)^ Chapel Hill, NC
Donald K. Bynum, M.D., Durtiam, NC
Culley C. Carson III, M.D., Durtiam, NC
Mauricio Castillo, M.D., Chapel Hill, NC
Robert C Cefakt, M.D^ Chapel Hill, NC
Richard L Claris, M.D., Chapel Hill, NC
Anna M. Connolly, M.D., Chapel Hill, NC
William J. Cromartie, MD., Chapel Hill, NC
Robert E. Cross, Ph.D., Durtiam, NC
Georgette A. Dent, M.D., Chapel Hill, NC
William Droegemueller, M.D., Chapel Hill, NC
Thomas M. Egan, M.D., Chapel Hill, NC
Frederic L Eldridge, M.D., Chapel Hill, NC
James E. Faber, M.D., Chapel Hill, NC
Paul B. Farel, Ph.D., Chapel Hill, NC
Janet Fischer, M.D., Chapel Hill, NC
Newton D. Fischer, M.D., Chapel Hill, NC
Donald T Forman, Ph.D., Chapel Hill, NC
Michael W. Fried, M.D., Chapel Hill, NC
William E. Garrett, M.D., Ph.D., Bahama,
NC

Peter H. Gilligan, Ph.D., Chapel Hill, NC
Joe W. Grisham, M.D., Chapel Hill, NC
John J. Haggerty, Jr., M.D., Chapel Hill, NC
William D. Heizer, M.D., Chapel Hill, NC
Jeffrey L Houpt, M.D., Chapel Hill, NC
David G. Kaufman, M.D., Ph.D., Chapel Hill,
NC

Ernest N. Kraybill, M.D., Chapel Hill, NC
Jan A. Kylstra, M.D., Chapel Hill, NC
H. R. Lesesne, M.D., Chapel Hill, NC
Kennetti J. Levin, M.D., Chapel Hill, NC
Jeffrey A. Liebeiman, M.D., Chapel Hill, NC
Carol N. Lucas, Ph.D., Chapel Hill, NC
G. Philip Manire, Ph.D., Chapel Hill, NC
Elizabeth S. Mann, M.D., Chapel Hill, NC
William D. Mattem. M.D., Chapel Hill, NC
Evelyn B. McCarthy, Ph.D., Chapel Hill, NC
Michael J. McMahon, M.D., Cantwro, NC
Campbell W. McMillan, M.D., Chapel Hill, NC
David F Merten, M.D., Pittstx)ro, NC
Anthony A. Meyer, M.D., Chapel Hill, NC
Don K. Nakayama, M.D., Chapel Hill, NC
Christian E. Newcomer Ph.D., Brookeville, MD
Tenry L. Noah, M.D., Carrboro, NC
Edward J. O'Keefe, M.D., Chapel Hill, NC
David A. Ontjes, M.D., Chapel Hill, NC
Anthony N. Passannante, M.D., Chapel Hill, NC
Edward R. Pert, MJ>^ Chapel Hill, NC
Joseph H. Perimutt, Ph.D., Chapel Hill, NC
Arthur J. Prange, Jr, M.D., Hillslxirough, NC

38

Desmond K. Runyan.M.D., Chapel Hill, NC
Robert S. Sandler, M.D,, Chapel Hill, NC
James H. Scatllff, M.D., Chapel Hill, NC
Eva Schaff, M.D., Pittstwro, NC

John T. Sessions, Jr., M.D., Chapel Hill, NC
George F Sheldon, M.D., Chapel Hill, NC
William W. Shocldey, M.D., Chapel Hill, NC
Sidney C. Smith, Jr, M.D., Chapel Hill, NC
Brian C. Stabler, Ph.D., Chapel Hill, NC
William G. Sullivan, M.D., Raleigh, NC
Timothy Taft, M.D., Chapel Hill, NC
Catherine A. Taylor, M.D., Chapel Hill, NC
Lesli A. Taylor, MD., Chapel Hill, NC
Joel E. Tepper M.D., Chapel Hill, NC
Colin G. Thomas, Jr., M.D., Chapel Hill, NC
Robert D, Valley M.D., Chapel Hill, NC
Charies M. Van Der Horsl M.D., Chapel Hill, NC
Judson J. Van Wyk, M.D., Chapel Hill, NC
Clarence E Whrtefield, Chapel Hill, NC
J. Kenneth Whitt, Ph.D., Chapel Hill, NC
Richard V Wolfenden, Ph.D., Chapel Hill, NC
Bonnie C. Yankastcas, Ph.D., Chapel Hill,
NC
James R Yanlcaslcas, M.D., Chapel Hill, NC

HOUSESTAFF
Robert l_ Abney III, M.D., Madison, MS
Nadia M. Anderson M.D., Durham, NC

James W. Asaph, lyl.D., Portland, OR

David E. Ballard, M.D., Albuquerque, NM

Thomas Ivl. Bashore, M.D., Durham, NC

Paul W. Biddinger, M.D., Cincinnati, OH

Pauline M. Blair, M.D., New Bern, NC

Robert S. Boger, M.D., Brookfiekj, CT

Leroy W. Bowersox, M.D., Oceanside, CA

Thomas A. Braci(t>iil, M.D., Greenstwro, NC

Marianne S, Breslin, M.D., Chapel Hill, NC

Maria T Britto, M.D., Cincinnati, OH

Boice R. Brodie. M.D,, Greenstwro, NC

Rotjert A. Brown, M.D,, Fort Myers, FL

Wallace D. Brown, M.D., Raleigh, NC

George F. Brumbacic, M.D., Greensboro, NC

Edwin L. Bryan, M.D., Greensboro, NC

Robert V Buccini, M.D., Greensboro, NC

William R. Bullock, M.D., Chariotte, NC

Holly J. Surge, M.D., Raleigh, NC

Leo B. Bustad, M.D., Anchorage, AK

Bnjce Cairns, M.D,. Chapel Hill, NC

Edmund R. Campion, M.D., Chapel Hill, NC

Robert L Carithers, Jr., M.D., Seattle, WA

G. Raybum Cheely, M.D., Raleigh, NC

David A. Ciaric, M.D., Delmar, NY

Thomas P Cornwall, M.D., Durtiam, NC

Ponjcla Coney, M.D., Springfield, IL

Stanley C. Cox 111, M.D., Southern Pines, NC

John T Cumes, M.D., Greenstxsro, NC

Frederic G. DaUdori, MJ>, Chapel Hill, NC

Joanna S. DaUdori, MJ>^ Chapel Hill, NC

Marsha L Davenport, M.D , Chapel Hill, NC

Donald G, Detweiler, M.D., Raleigh, NC

Thomas E. Digby, M.D., Newton, NJ

Edgar S. Douglas, Jr, M.D., Greenville, NC

Michael F Durfee, M.D., Raleigh, NC

James E Eadens, M.D., Sarasota, FL

Steven R. Feldman, M.D., Winston-Salem, NC

Timothy R. Fengler, M.D, Columbia, SC

Gary J. Fischer, M.D., Greensboro, NC

Catherine A. Fomeris, M.D., Chapel Hill, NC

Charies E. Frederick, M.D., Greensboro, NC

William A. Fricke, M.D., Rochester, NY

Giuliana G. Gage, M.D., Raleigh, NC

James C. Gartjutt M.D., Pittsboro, NC

Matthew W. Gillman, M.D., Jamaica Plain, MA

Brian M. Go, M.D., Raleigh, NC

Robert N. Golden, M.D., Chapel Hill, NC

Daniel Gottovl, M.D., Wilmington, NC

Lawrence H. Greentserg, M.D., Cary, NC

John D. Grizzard, M.D., Midtothian, VA

Lany D. Grubb, M.D., Florence, SC

Stephen A. Grubb, IM.D., Independence, VA

Jagmohan D. Gupta, M.D., GokJstxjro, NC

Robert D. Hagberg, M.D., Forest City, NC

D. Allen Hayes, M.D., Raleigh, NC

Glenn B. Hays, M.D., North Fort Myers, FL

Richard R. Henderson, M.D., Elon, NC

Michael A. Hill, M.D., Chapel Hill, NC

Charies J. Hodulik M.D., Madison, Wl

Robert P Hollowell, Jr, M.D., Cary, NC

Daniel T Howell, M.D., Cary, NC

Robert R. Huntley, M.D.,and Joan C.

Huntley, Ph.D., Chapel Hill, NC

Burton R. Hutto, M.D., Chapel Hill, NC

Susan L Hyman, M.D., Rochester, NY

Harold N. Jacklin, M.D., Greensboro, NC

Peter C. Jacobson, M.D., Virginia Beach, VA

All Jarrahi, M.D., Winston-Salem, NC

J, Jeff Johnson, M.D., Paducah, KY

F Douglas Jones, M.D., Greenville, NC

Janine C. Jones, M.D., Nicholasville, KY

Raleigh 0. Jones, Jr, M.D., Nicholasville, KY

Hisashi K^jiicuri, M.D., Monterey, CA

Jeffrey D. Katz, M.D., Greensboro, NC

Shannon C. Kenney, M.D., Chapel Hill, NC

Tong-Su Kim, M.D., Hickory, NC

Steven C. Klein, M.D., Greensboro, NC

John F. Koepice, M.D., Dunwoody, GA

Jonathan S. Krauss, M.D., Augusta, GA

Walter L Lantar, M.D^ Tiilsa, OK

Joseph J. Lawton III, M.D., Columbia, SC

Margaret W. Leigh, M.D., Chapel Hill, NC

John R. Una, M.D., Southern Pines, NC

Thomas B. Logan, M.D., Henderson, KY

Gerald J. Longa, M.D., Terre Haute, IN

Jane L Madison, M.D., Chapel Hill, NC

H. Raymond Madry, Jr., M.D., Raleigh, NC

Bruce T Malentaum, M.D., Durham, NC

Peter J. Massicott, M.D., Boston, MA

James G. McCiure, M.D., Memphis, TN

W. Elenson McCutcheon, Jr., M.D., Durham,

NC

tvlorton Meltzer, M.D., Cameron, NC

Steven L Mendelsohn, M.D , Asheville, NC

Donald B. Middleton, M.D., Pittsburgh, PA

Aftef A Mikhail, M.D., Pari< Hills, KY

David K. Mlllward, M.D., Raleigh, NC

James J Murphy M.D., Anden, NC

Albert J. Naftel, Jr, M.D , Chapel Hill, NC

Charies L Nance, Jr, M.D., Wilmington, NC

Keith A. Nance, M.D., Raleigh, NC

William E. Nelson, M,D., APO, AE

Andraos N. Nicola, M.D., Graham, NC

John W. Oglesby M.D., Nashville, TM

Jeffrey A. Okamoto, M.D., Letsanon, PA

Frederick H. Opper, M.D., Wilmington, NC

Louis V. Pacilio, M.D., Leeds, MA

Edward N. Pattishall, M.D., Chapel Hill, NC

Robert F Patton, M.D., Chapel Hill, NC

Herbert B. Peterson, M.D., Commugny

SWITZERLAND

George H. Pierson, Jr., M.D., Greensboro, NC

Cedric W. Porter, Jr, M.D., Asheville, NC

William C. Powell, M.D., Fayettevilie, NC

Robert K. Ramsey, M.D., Lakeland, FL

Bradley B. Randall, M.D., Sk>ux Fails, SD

Rupa C. Redding-Ullinger, M.D., Chapel Hill, NC

Mary B. Rippon, M.D., Greenville, SC

Hal J. Rollins, Jr, M.D., Greensboro, NC

Robert L Rollins, Jr, M,D., Raleigh, NC

Billy W. Royal, M,D., Chapel Hill, NC

William G. Ryan, M.D., Birmingham, AL

Nat H. Sandler, M.D., Lexington, KY

Peter L. Saviteer, M.D., Hopkinton, NH

Roland E. Schmidt M.D., Chapel Hill, NC

Stephen B. Schuster, M.D., Greensboro, NC

Katherine M. Shea, M.D., Chapel Hill, NC

Stephanie A. Skolik M.D., Huntington, WV

David A. Smith, M.D., Chapel Hill, NC

Bryan W. Smith, M.D., Chapel Hill, NC

John J. Solic, M.D., State College, PA

Dixie U Soo, M.D., Chapel Hill, NC

Liang Y. Soo, M.D., Chapel Hill, NC

Ernest B. Spangler, Jr^ M.D^ Greensboro,

NC

Stanley M. Spinola, M.D., Indianapolis, IN

Steven J. Stafford, M.D., Raleigh, NC

Hale H. Stephenson, M.D., Greenville, NC

Mary C. Steuterman, M.D., Greensboro, NC

Thomas M. Swantfcowski, M.D., Southern

Pines, NC

Bonnie S. Szymlk, M.D., Aiken, SC

Eugene E. Taylor, M.D., Milwaukie, OR

Norman A. Thome, M.D., Hertford, NC

R. Edgar Timberiake, Jr., M.D., Lexington,

NC

Steven I- THicy, M.D., Gastonia, NC

George P Vennart, M.D., Richmond, VA

Cheryl A. Viglione, M.D,, Greensboro, NC

George L Wallace, Jr, M.D., Martinsville, VA

Peter A. Wallenbom III, M.D., Asheville, NC

Torin P Walters, M.D., Huntington, WV

David I- WatMns M.D., Dallas, TX

Camngton W. White, M.D., Durtiam, NC

Robert W. Whrtener, M.D., Greensboro, NC

Frances K. Widmann, M.D., Chapel Hill, NC

Robert K. Wilson, Jr, M.D., Pensacola, FL

George T Wolff, M.D., GreenstDoro, NC

John T Woosley, M.D., Ph.D., Chapel Hill, NC

H. Unton Wray M.D., Chevy Chase, MD

Peter R. Young, Sr, M.D., Greenstwro, NC

Nakleh P. Zarzar, M.D., Raleigh, NC

Mary E. Zelenik, M.D., Cliflon Forge, VA

Thomas A. Zirker, M.D., Greenstwro, NC

By now, most of you have completed your vacations, have survived the heat
of summer, the kids are back in school, and it's time to settle into our usual routines.
For myself, there is a different sensation that has transpired because of more involve-
ment with the Medical Alumni Association. There is a certain renewal of spirit that
occurs when you see the enthusiasm and excitement of a new class of medical stu-
dents begin their journey that we have all experienced. The alumni reunion committees
are being formed, and the work begins for a new year.

For the majority of our alumni, this feeling of renewed commitment to the
School of Medicine occurs only once in every five years. We are all very busy and
wrapped up in our own worlds and do not have the annual stimulus of change that
occurs at our alma mater. Does it have to be this way? Certainly not. Just because we
are not on the actual scene of excitement that occurs in Chapel Hill does not mean we
cannot renew our commitments to the School of Medicine. Just because our classes
do not reunite every year has nothing to do with us examining our responsibilities for
supporting the institution that gave us our start.

In my previous letter, I mentioned the apathy that one sees in our profession.
It is easy to justify or write off this attitude when we continually are bombarded by a
host of acronymic organizations - HCFA, HMO, PPO, for example - that affect our pro-
fessional lives. Instead of giving in to these pressures, it is much more satisfying to
renew our efforts and commitments to those things most dear to us.

All of these rah-rah reminders of renewed spirit can mean that each of us will
make a commitment to become involved in alumni activities. What can we do to learn
more about what goes on at the School of Medicine? How can we strengthen our ties
and lend our support; become involved in committees and campaigns and
attend events and receptions that can rejuvenate our lives? Such interest not only
translates into a new vision for our school, but also can enrich and improve the life of
our community.

Before time slips away — and it has a habit of doing that - take this opportu-
nity to close your eyes and imagine you have been transposed to the past ... 10, 20,
even 50 years ago. Remember the excitement of that new beginning. Think of what this
has meant to you and take stock of what you can do to make things better — not just
every five years at a reunion, but each day of our lives

I look forward to seeing each of you at the next reunion or Dean's Reception.

(^-^

Thomas J. Koontz, MD, '66

Nov. 2-3 - Chapel Hill

11th Annual Vascular Surgery Symposium

Nov. 2-4 - Chapel Hill

UNC RSRC Clinical Instructor Seminar Series
2001 - Part II

Nov. 13 - Chapel Hill

Advances in Pediatric Pain Management

Nov. 16-18 -Chapel Hill

Psychiatry Across the Ages: 6th Annual Update in
Psychiatry and the 18th Annual George C. Ham
Symposium

Jan. 17-18 -Chapel Hill

Challenges in Geriatric Practice: 13th Annual
Conference

March 7. 12, 19, 26, April 2 - Chapel Hill

Mini Medical School Lecture Series 2002

April 4-5 - Charleston, S.C.

Bridging Research and Practice in Urinary
Incontinence

April 5-6 - Chapel Hill

Symposium on Tissue Factor and Factor VII

April 10-12 -Chapel Hill

26th Annual Internal Medicine Conference
The Friday Center

April 19-21 - Chapel Hill

Spring Medical Alumni Weekend

For more information, go to
www.med.unc.edu/alumni and
www.med.unc.edu/cme

r

Many individuals would like to make a major gift to the UNC
medical center, but cannot commit current assets for such a
purpose. Through a will, however, anyone can make a more
significant gift than they might ever have thought possible by
designating a specific sum, a percentage, or the residue of their
estate for the benefit of the medical center.

To provide a bequest, simply include a paragraph in your will
naming The Medical Foundation of North Carolina, Inc. as a
beneficiary. For example:

JorL

"I give, devise and bequeadi (the sum of$

% of my estate) or (the residue of my estate) to The Medical
Foundation of North Carolina, Inc, a 501(C)(3) created to maintain
funds for the UNC medical center with principal offices located at
880 Airport Road, Chapel Hill, North Carolina.

This language creates an unrestricted bequest for use by the
medical center when and where the need is greatest, or you may
specify that your gift t>e used for a partk:ular purpose.

For further information on t>equests, contact Jane McNeer at
(919) 966-1201, (800) 962-2543, orjmcneer@email.unc.edu.

II